GO:0051902

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Name negative regulation of mitochondrial depolarization
Categary Process
Go Slim No
Go Link GO:0051902
Unique Molecular Interactions 99
Total Molecular Interactions 151
Total Single Events 1269
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of mitochondrial depolarization. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of mitochondrial depolarization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT73539 Binding of Ngf and Ngfr 5 0.45 3.99 4
2 INT222335 Binding of Bdnf and Ngfr 3 0.05 2.66 1.48
3 INT280480 Binding of Bdnf and Ngfr 5 0.25 3.14 1.27
4 INT256041 Binding of Ngfr and Ntrk1 3 0.14 0.9 1.13
5 INT82024 Binding of Ngfr and Ngf 2 0.33 1.48 1.05
6 INT76001 Ngf Positive_regulation of Ngfr 1 0.16 0.93 1.05
7 INT242642 Binding of BDNF and Ngfr 2 0.21 1.38 1.01
8 INT73538 Ngf Positive_regulation of Ngfr 2 0.41 1.05 0.85
9 INT213726 Binding of Ngfr and Ntrk1 1 0.14 0.96 0.72
10 INT289333 Binding of Ngfr and Rtn4r 1 0.03 2.35 0.72
11 INT289332 Binding of Ngfr and Lingo1 1 0.04 2.36 0.72
12 INT320633 Positive_regulation of MAPK1 Regulation of BCL2 1 0.04 1.21 0.7
13 INT82021 Negative_regulation of Binding of Ngfr and Ngf 1 0.29 0.32 0.69
14 INT289357 Ngfr Positive_regulation of Akt1 1 0.03 3.1 0.66
15 INT134532 Grin2a Regulation of Ngfr 1 0.02 0 0.57
16 INT134528 Grin1 Regulation of Ngfr 1 0.03 0 0.57
17 INT134531 Gria1 Regulation of Ngfr 1 0.01 0 0.57
18 INT76002 Ngf Positive_regulation of Ngfr 1 0.05 0.48 0.53
19 INT245558 Runx3 Regulation of Ngfr 1 0.06 1 0.53
20 INT161227 Binding of Ngfr and Tnf 1 0.06 0.41 0.49
21 INT120295 Ngf Positive_regulation of Positive_regulation of Ngfr 1 0.47 0.22 0.43
22 INT73537 Ntf3 Positive_regulation of Ngfr 1 0.21 0.1 0.38
23 INT73536 Ngf Regulation of Ngfr 1 0.22 0.08 0.37
24 INT264555 IL15 Positive_regulation of Gene_expression of BCL2 1 0.02 0.92 0.35
25 INT112283 Bdnf Regulation of Gene_expression of Ngfr 1 0.14 0.28 0.34
26 INT237927 BCL2 Positive_regulation of BAX 2 0.24 2.22 0.26
27 INT237928 BCL2 Positive_regulation of FAS 1 0.02 1.41 0.26
28 INT237925 BCL2 Positive_regulation of Protein_catabolism of PARP1 1 0.02 1.42 0.26
29 INT302170 PTGER2 Positive_regulation of Gene_expression of BCL2 1 0.04 3.76 0.23
30 INT241451 Mag Positive_regulation of Ngfr 1 0.09 0.1 0.21
31 INT308654 Binding of Ngfr and Nts 1 0.06 0.39 0.21
32 INT176133 AKT1 Regulation of BCL2 2 0.12 1.84 0.17
33 INT280486 Binding of Ngfr and Ntrk2 2 0.18 1.21 0.17
34 INT155233 TXNIP Regulation of BCL2 1 0.23 0.15 0.17
35 INT347445 CD99 Positive_regulation of BCL2 1 0.17 0.95 0.16
36 INT241462 Binding of OMG and Ngfr 1 0.11 0.15 0.15
37 INT241457 Binding of Mag and Ngfr 1 0.09 0.15 0.15
38 INT241453 Binding of Ngfr and Rtn4r 1 0.03 0.15 0.15
39 INT311666 Binding of BCL2 and TP53 1 0.19 1.26 0.14
40 INT95104 TGFBR2 Positive_regulation of BCL2 1 0.08 0.61 0.14
41 INT148594 Binding of BCL2 and CD34 1 0.39 1.17 0.13
42 INT342311 Binding of Tp53 and Positive_regulation of Gene_expression of BCL2 1 0.08 1.25 0.13
43 INT348542 BCL2 Negative_regulation of NLRP1 1 0.07 2.02 0.13
44 INT178101 EDN1 Negative_regulation of Phosphorylation of BCL2 1 0.03 1 0.12
45 INT349858 Binding of Ngfr and Ntrk2 1 0.09 0.32 0.11
46 INT265888 BCL2 Regulation of Gene_expression of BAD 1 0.04 1.08 0.1
47 INT280493 Ngfr Regulation of Protein_catabolism of BDNF 1 0.09 0.14 0.1
48 INT265890 BCL2 Regulation of Gene_expression of BAX 1 0.04 1.08 0.1
49 INT239643 Binding of BCL2 and BCL2L11 3 0.16 2.26 0.09
50 INT282094 Apoa2 Negative_regulation of BCL2 1 0.06 1.15 0.09
51 INT265887 IGF1 Negative_regulation of BCL2 1 0.09 1.02 0.09
52 INT164675 Binding of NGF and Ngfr 1 0.00 0.5 0.08
53 INT164676 Negative_regulation of Binding of NGF and Ngfr 1 0.00 0.5 0.08
54 INT302177 PTGER2 Positive_regulation of BCL2 1 0.04 2.08 0.06
55 INT352299 Regulation of Binding of BCL2 and VIM 1 0.10 1.07 0.06
56 INT352298 Binding of BCL2 and VIM 1 0.09 1.06 0.06
57 INT201766 Binding of RIPK2 and Ngfr 1 0.02 0.41 0.04
58 INT192164 Binding of BAK1 and BCL2 3 0.04 2.8 0.03
59 INT192167 Negative_regulation of Binding of BAK1 and BCL2 2 0.05 1.89 0.03
60 INT241449 Mag Positive_regulation of Protein_catabolism of Ngfr 1 0.09 0 0.03
61 INT217148 MIR21 Regulation of BCL2 1 0.32 0.98 0.03
62 INT201732 Ngfr Positive_regulation of Nfkb1 1 0.01 0.43 0.03
63 INT178861 Binding of BAX and BCL2 3 0.27 3.07 0
64 INT292454 Binding of BAD and BCL2 2 0.03 1.73 0
65 INT144032 STAT3 Regulation of BCL2 2 0.07 0.86 0
66 INT217150 MIR16-2 Regulation of BCL2 2 0.09 1.89 0
67 INT217137 MIR15B Regulation of BCL2 2 0.15 1.88 0
68 INT200063 Binding of MAGED1 and Ngfr 1 0.44 0.45 0
69 INT321406 VEGFA Regulation of BCL2 1 0.01 0.75 0
70 INT292503 Mlph Regulation of Gene_expression of BCL2 1 0.00 0.4 0
71 INT348531 Binding of BCL2 and BECN1 1 0.06 0.43 0
72 INT280566 Binding of ARAF and BCL2 1 0.02 0.69 0
73 INT338013 Binding of Ngfrap1 and Ngfr 1 0.06 1.3 0
74 INT200062 Binding of Ngfr and Bbs4 1 0.30 0.3 0
75 INT315060 PAR4 Regulation of BCL2 1 0.53 0.48 0
76 INT327972 Negative_regulation of BCL2 Positive_regulation of BAX 1 0.22 0.82 0
77 INT200053 Binding of Nuc and Ngfr 1 0.10 0.3 0
78 INT268516 Gene_expression of MIR16-2 Positive_regulation of Gene_expression of BCL2 1 0.00 1.15 0
79 INT335953 Binding of BCL2 and Bad 1 0.14 0.37 0
80 INT198021 Binding of BCL2 and MCL1 1 0.17 2.88 0
81 INT200057 Binding of Ndn and Ngfr 1 0.43 1.96 0
82 INT292458 Negative_regulation of Binding of BAD and BCL2 1 0.01 0.81 0
83 INT327977 TNFRSF11A Regulation of BCL2 1 0.05 0.67 0
84 INT320346 Binding of Ngfr and Np4 1 0.01 0 0
85 INT189673 BCL2 Positive_regulation of Transcription of TERT 1 0.09 0 0
86 INT201742 Binding of Ngfr and Gtf3a 1 0.00 0.77 0
87 INT201774 Binding of BCL2 and BCL2L1 1 0.00 0.37 0
88 INT292461 PTK2 Regulation of BCL2 1 0.02 0.76 0
89 INT200061 Binding of Ngfr and Fez1 1 0.31 0.3 0
90 INT217141 Binding of BCL2 and MIR15B 1 0.21 1.26 0
91 INT193965 Binding of BCL2 and Ps 1 0.05 0.59 0
92 INT327976 PNLIP Negative_regulation of Gene_expression of BCL2 1 0.29 0.53 0
93 INT217146 Binding of BCL2 and MIR16-2 1 0.12 1.25 0
94 INT290372 Binding of Ngfr and Scarb1 1 0.01 0.48 0
95 INT327974 GOPC Regulation of Gene_expression of BCL2 1 0.13 0.6 0
96 INT201538 Binding of BCL2 and NPC1 1 0.17 1.41 0
97 INT201741 Binding of Rhoa and Ngfr 1 0.01 1 0
98 INT200055 Binding of Ngfr and Mageh1 1 0.33 0.45 0
99 INT185853 Binding of BCL2 and BIK 1 0.36 0.59 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of mitochondrial depolarization. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of mitochondrial depolarization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73
2 INT55908 Gene_expression of Ngfr 74 0.78 34.46 28.8
3 INT46016 Gene_expression of Ngfr 69 0.77 41.22 19.8
4 INT66038 Positive_regulation of Ngfr 32 0.69 26.07 11.75
5 INT70017 Positive_regulation of BCL2 87 0.67 66.62 8.68
6 INT75921 Negative_regulation of Ngfr 13 0.59 8.58 8.35
7 INT65959 Positive_regulation of Gene_expression of BCL2 75 0.70 77.3 8.27
8 INT48310 Binding of Ngfr 25 0.48 9.72 8.16
9 INT61542 Positive_regulation of Ngfr 15 0.70 6.35 7.34
10 INT78713 Negative_regulation of Ngfr 9 0.54 7.07 6.73
11 INT84685 Regulation of BCL2 67 0.60 72.96 6.65
12 INT70613 Negative_regulation of Gene_expression of BCL2 48 0.59 38.91 5.22
13 INT73262 Negative_regulation of BCL2 67 0.57 61.01 5.07
14 INT64711 Regulation of Ngfr 10 0.45 3.12 4.33
15 INT121170 Positive_regulation of Gene_expression of Ngfr 10 0.64 9.32 3.94
16 INT121171 Negative_regulation of Gene_expression of Ngfr 6 0.58 3.46 3.89
17 INT55907 Binding of Ngfr 13 0.47 5.79 3.75
18 INT61540 Negative_regulation of Gene_expression of Ngfr 11 0.59 6.36 3.43
19 INT109403 Regulation of Gene_expression of BCL2 31 0.60 31.22 3.4
20 INT61541 Positive_regulation of Gene_expression of Ngfr 7 0.53 2.87 2.75
21 INT75225 Transcription of Ngfr 4 0.60 1.95 2.44
22 INT64712 Localization of Ngfr 4 0.78 1.19 1.91
23 INT137513 Negative_regulation of Positive_regulation of BCL2 6 0.35 5.3 1.62
24 INT140247 Negative_regulation of Negative_regulation of Ngfr 3 0.33 3.15 1.59
25 INT163594 Regulation of Ngfr 5 0.43 2.55 1.53
26 INT64713 Regulation of Gene_expression of Ngfr 4 0.50 2.04 1.36
27 INT138939 Positive_regulation of Transcription of Ngfr 3 0.43 0.89 1.31
28 INT164372 Positive_regulation of Positive_regulation of Ngfr 6 0.62 4.1 1.22
29 INT110392 Transcription of Ngfr 3 0.52 2.48 1.19
30 INT70021 Localization of BCL2 23 0.74 21.6 1.09
31 INT163595 Positive_regulation of Regulation of Ngfr 1 0.46 0.57 1.04
32 INT92117 Phosphorylation of BCL2 26 0.80 9.93 0.86
33 INT70019 Binding of BCL2 25 0.47 17.55 0.79
34 INT109404 Transcription of BCL2 6 0.69 4.49 0.77
35 INT317733 Positive_regulation of Binding of Ngfr 1 0.18 0.51 0.71
36 INT133018 Regulation of Gene_expression of Ngfr 2 0.43 1.47 0.7
37 INT70025 Positive_regulation of Positive_regulation of BCL2 3 0.27 0.96 0.58
38 INT139929 Phosphorylation of Ngfr 3 0.58 1.67 0.57
39 INT118729 Regulation of Transcription of Ngfr 1 0.36 0.45 0.57
40 INT178128 Negative_regulation of Phosphorylation of BCL2 7 0.27 3.94 0.56
41 INT155090 Regulation of Positive_regulation of BCL2 3 0.26 1.78 0.54
42 INT110393 Positive_regulation of Transcription of Ngfr 1 0.46 1 0.54
43 INT140295 Protein_catabolism of BCL2 4 0.64 5.7 0.44
44 INT165518 Positive_regulation of Regulation of Ngfr 2 0.47 0.47 0.37
45 INT178114 Positive_regulation of Phosphorylation of BCL2 11 0.49 4.44 0.28
46 INT297460 Regulation of Regulation of Ngfr 1 0.33 0.32 0.21
47 INT238507 Regulation of Regulation of BCL2 3 0.44 5.14 0.16
48 INT229235 Regulation of Localization of BCL2 2 0.29 3.7 0.15
49 INT297459 Protein_catabolism of Ngfr 1 0.21 0.5 0.1
50 INT302229 Negative_regulation of Negative_regulation of BCL2 3 0.21 2.69 0.04
51 INT258045 Positive_regulation of Regulation of BCL2 2 0.36 1.78 0.03
52 INT241405 Localization of Ngfr 2 0.56 0.4 0.03
53 INT241402 Protein_catabolism of Ngfr 1 0.39 0 0.03
54 INT310419 Negative_regulation of Localization of BCL2 3 0.41 2.51 0
55 INT185909 Regulation of Phosphorylation of BCL2 3 0.24 1.63 0
56 INT185887 Regulation of Binding of BCL2 2 0.24 2.22 0
57 INT183619 Negative_regulation of Regulation of BCL2 2 0.33 1.01 0
58 INT153083 Positive_regulation of Negative_regulation of BCL2 2 0.32 2.9 0
59 INT330962 Negative_regulation of Transcription of BCL2 1 0.10 1.21 0
60 INT193880 Regulation of Phosphorylation of Ngfr 1 0.02 0.25 0
61 INT201629 Negative_regulation of Positive_regulation of Ngfr 1 0.07 0.37 0
62 INT356124 Positive_regulation of Transcription of BCL2 1 0.45 0.3 0
63 INT184508 Positive_regulation of Localization of BCL2 1 0.07 0.87 0
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