GO:0051918

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Name negative regulation of fibrinolysis
Categary Process
Go Slim No
Go Link GO:0051918
Unique Molecular Interactions 319
Total Molecular Interactions 485
Total Single Events 3044
Pain Genes Associated 18

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of fibrinolysis. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of fibrinolysis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT24689 Binding of PLAT and Serpine1 1 0.00 3.77 1.64
2 INT56093 FGFR1 Regulation of Gene_expression of SERPINE1 1 0.23 1.71 1.37
3 INT56087 TNF Regulation of Gene_expression of SERPINE1 1 0.43 1.67 1.33
4 INT150794 ZNF398 Positive_regulation of Localization of THBS1 1 0.09 1.02 1.07
5 INT150789 THBS3 Negative_regulation of THBS1 1 0.18 1.01 1.06
6 INT195668 Binding of F2 and THBD 7 0.08 5.67 0.98
7 INT195219 Binding of CPB2 and CSRP1 1 0.03 0.99 0.96
8 INT107001 F2 Positive_regulation of PAR1 4 0.05 2.15 0.92
9 INT138602 Negative_regulation of BCL2L2 Positive_regulation of F2 1 0.00 0.67 0.92
10 INT138601 BCL2L2 Positive_regulation of F2 1 0.00 0.66 0.91
11 INT111924 Cpb2 Negative_regulation of Positive_regulation of Plg 1 0.02 1.29 0.9
12 INT153516 PLG Positive_regulation of Pas5a 1 0.57 0.05 0.83
13 INT16488 Binding of Serpinf2 and Crp 1 0.00 0.78 0.78
14 INT16491 Binding of ADRA1D and Serpinf2 1 0.02 0.78 0.78
15 INT16494 Binding of LPA and Serpinf2 1 0.00 0.78 0.78
16 INT16492 Positive_regulation of Binding of LPA and Serpinf2 1 0.00 0.78 0.78
17 INT16493 Positive_regulation of Binding of ADRA1D and Serpinf2 1 0.02 0.78 0.78
18 INT16489 Positive_regulation of Binding of Serpinf2 and Crp 1 0.00 0.78 0.78
19 INT106999 F2 Positive_regulation of PAR4 3 0.06 1.83 0.72
20 INT106992 F2 Positive_regulation of PARD3 3 0.05 1.83 0.72
21 INT150338 Binding of F2 and F2R 1 0.11 0.4 0.67
22 INT130355 spc Regulation of Serpine1 1 0.14 0.2 0.66
23 INT130354 Adcy10 Regulation of Serpine1 1 0.17 0.2 0.66
24 INT99728 Binding of F13A1 and PLG 4 0.02 2.51 0.63
25 INT302469 F2 Positive_regulation of Gene_expression of MMP9 1 0.01 1.82 0.62
26 INT284089 Binding of NTRK2 and SERPINE1 1 0.27 0.73 0.61
27 INT56088 TGFB1 Positive_regulation of Transcription of SERPINE1 1 0.46 0.83 0.57
28 INT195666 Binding of PROC and THBD 2 0.40 2.42 0.56
29 INT99736 Binding of PLG and Serpinf2 1 0.01 0.73 0.55
30 INT150791 THBS1 Negative_regulation of TIMP2 1 0.17 0.5 0.52
31 INT130561 NCKIPSD Regulation of SERPINF2 1 0.22 0 0.52
32 INT150796 ZNF398 Positive_regulation of THBS1 1 0.06 0.5 0.52
33 INT150785 THBS1 Negative_regulation of MMP2 1 0.10 0.5 0.52
34 INT195220 Binding of CPB2 and IL6 1 0.04 0.5 0.49
35 INT84515 IRF6 Positive_regulation of Gene_expression of F2 1 0.02 0.15 0.49
36 INT84520 Gene_expression of F2 Positive_regulation of F13A1 1 0.03 0.16 0.49
37 INT341622 Binding of F2 and CTRC 1 0.06 1.22 0.46
38 INT173295 F2 Positive_regulation of OR1S1 1 0.01 0.15 0.46
39 INT22674 Binding of SERPINE1 and PLAT 7 0.04 0.65 0.45
40 INT48715 PTGER2 Regulation of Gene_expression of SERPINE1 1 0.21 0.6 0.44
41 INT48716 IL1B Regulation of Gene_expression of SERPINE1 1 0.42 0.59 0.44
42 INT162043 F2 Positive_regulation of Gene_expression of OSM 1 0.44 1.13 0.41
43 INT162041 F2 Positive_regulation of Positive_regulation of FOS 1 0.13 1.14 0.41
44 INT48714 PTGER2 Negative_regulation of Gene_expression of SERPINE1 1 0.15 0.28 0.38
45 INT130930 Egr1 Negative_regulation of Positive_regulation of Thbs1 1 0.58 0.64 0.38
46 INT198652 F2 Positive_regulation of Gene_expression of CD36 1 0.03 1.32 0.37
47 INT161004 Binding of Cpe and Cpb2 1 0.03 0.53 0.37
48 INT99738 Binding of F13A1 and Serpinf2 1 0.00 0.49 0.37
49 INT161006 Itgam Regulation of Cpb2 1 0.07 0.52 0.37
50 INT161003 Binding of Itgam and Cpb2 1 0.10 0.52 0.37
51 INT161007 Gfap Regulation of Cpb2 1 0.04 0.52 0.37
52 INT160999 Binding of Gfap and Cpb2 1 0.14 0.52 0.37
53 INT302466 Positive_regulation of F2 Positive_regulation of Gene_expression of MMP9 1 0.01 1.1 0.35
54 INT354886 Thbs1 Regulation of Positive_regulation of Tgfb1 1 0.17 2.18 0.34
55 INT126531 Adra1a Positive_regulation of Serpine1 1 0.03 0.31 0.34
56 INT214854 SERPINE1 Positive_regulation of PLAT 1 0.24 0.42 0.33
57 INT56089 TGFB1 Regulation of SERPINE1 1 0.41 0.41 0.33
58 INT56090 TNF Regulation of SERPINE1 1 0.43 0.41 0.33
59 INT318299 Binding of F2 and PRTN3 1 0.01 1.92 0.33
60 INT312803 F2 Positive_regulation of NPEPPS 1 0.01 1.32 0.32
61 INT138469 Cpb2 Negative_regulation of Gene_expression of Ryr2 1 0.04 0.25 0.32
62 INT312802 F2 Positive_regulation of Binding of NPEPPS 1 0.01 1.33 0.32
63 INT123397 F2 Positive_regulation of Gene_expression of PTAFR 1 0.05 0.51 0.32
64 INT15685 Binding of PLAT and Serpine1 3 0.36 1.01 0.31
65 INT142286 Binding of PLG and Plat 2 0.52 0.7 0.31
66 INT162042 F2 Regulation of OSM 1 0.17 1.17 0.31
67 INT195669 Binding of F2 and PROC 1 0.04 1.44 0.31
68 INT265826 Binding of ACE and SERPINE1 1 0.24 1.08 0.3
69 INT162045 F2 Positive_regulation of Phosphorylation of MAPK3 1 0.30 0.99 0.3
70 INT56092 FGFR1 Positive_regulation of Transcription of SERPINE1 1 0.29 0.41 0.29
71 INT162039 F2 Regulation of Gene_expression of OSM 1 0.29 0.94 0.29
72 INT162044 F2 Positive_regulation of Localization of FOS 1 0.32 0.9 0.28
73 INT56091 FGF2 Positive_regulation of Transcription of SERPINE1 1 0.43 0.41 0.28
74 INT162040 F2 Positive_regulation of Localization of JUN 1 0.20 0.9 0.28
75 INT171050 Negative_regulation of F13A1 Regulation of PLG 1 0.02 0.55 0.28
76 INT252806 F2 Positive_regulation of Gene_expression of CCL2 1 0.01 0.8 0.27
77 INT171048 F13A1 Regulation of PLG 1 0.02 0.55 0.27
78 INT231025 Cpb2 Positive_regulation of Gene_expression of Fos 1 0.20 0.19 0.27
79 INT231030 Cpb2 Regulation of Gene_expression of Fos 1 0.11 0.31 0.27
80 INT203733 Thbs1 Positive_regulation of Negative_regulation of Ppara 1 0.36 1.55 0.26
81 INT282649 Binding of THBD and PROCR 1 0.40 0.97 0.26
82 INT76081 Plg Positive_regulation of Gene_expression of IL6 1 0.03 0.18 0.26
83 INT76082 Plg Regulation of Gene_expression of IL6 1 0.01 0.19 0.26
84 INT308120 Binding of F2 and F10 2 0.07 1.25 0.25
85 INT180964 PLG Positive_regulation of MMP13 1 0.24 0.45 0.25
86 INT31097 Binding of Penk and Plg 1 0.29 0.07 0.24
87 INT252356 Binding of THBS1 and Cd47 1 0.00 0.44 0.24
88 INT341538 F2 Positive_regulation of F2RL1 1 0.02 0.68 0.24
89 INT230751 Agtr2 Positive_regulation of Gene_expression of Serpine1 1 0.03 1.3 0.23
90 INT63420 F2 Positive_regulation of Gene_expression of ITGA2B 1 0.14 0.45 0.23
91 INT216911 Positive_regulation of P2rx7 Positive_regulation of Localization of Plg 1 0.02 0.13 0.23
92 INT250783 APC Negative_regulation of SERPINE1 1 0.06 0.86 0.23
93 INT63421 F2 Positive_regulation of Gene_expression of SELP 1 0.09 0.45 0.23
94 INT250782 APC Negative_regulation of F2 1 0.00 0.86 0.23
95 INT173292 F2 Positive_regulation of EGF 1 0.00 0.07 0.23
96 INT175910 SERPINE1 Negative_regulation of PLAU 1 0.06 1.01 0.22
97 INT175911 Binding of SERPINE1 and CNBP 1 0.01 1.02 0.22
98 INT48713 PTGER1 Negative_regulation of Gene_expression of SERPINE1 1 0.02 0.28 0.22
99 INT252357 Binding of THBS1 and Cd36 2 0.01 2.4 0.21
100 INT202184 SERPINE1 Regulation of Protein_catabolism of PLAUR 1 0.23 1.25 0.21
101 INT255257 Binding of Serpine1 and Tsp1 1 0.07 0.85 0.2
102 INT115006 Binding of Serpine1 and Cpb2 1 0.09 1.53 0.2
103 INT255259 Binding of Plg and Tsp1 1 0.05 0.84 0.2
104 INT27675 Plg Positive_regulation of Protein_catabolism of F13A1 1 0.00 0.75 0.2
105 INT99735 Binding of PLG and Ppp1r1a 1 0.00 0.24 0.19
106 INT338391 Thim Positive_regulation of Cpb2 1 0.08 0.37 0.19
107 INT99731 Binding of Serpinf2 and Ppp1r1a 1 0.00 0.24 0.19
108 INT99727 Binding of SERPINE1 and PLG 1 0.02 0.24 0.19
109 INT99734 Binding of SERPINE1 and Serpinf2 1 0.00 0.25 0.19
110 INT46306 Asrgl1 Positive_regulation of Negative_regulation of Plg 1 0.01 1.07 0.19
111 INT305003 HIF1A Regulation of SERPINE1 1 0.11 2.3 0.19
112 INT253776 Binding of THBD and F2 1 0.00 1.15 0.18
113 INT337260 ELL Positive_regulation of Gene_expression of THBS1 1 0.11 0.82 0.18
114 INT271451 TGFB1 Regulation of Serpine1 1 0.00 0.68 0.18
115 INT337263 ELL Regulation of Gene_expression of THBS1 1 0.10 0.82 0.18
116 INT97820 Serpine1 Negative_regulation of TIMP1 1 0.00 0.29 0.17
117 INT83514 SERPINC1 Negative_regulation of F2 2 0.16 0.62 0.16
118 INT158613 Binding of Serpine1 and Vtn 1 0.02 0.95 0.16
119 INT301907 Binding of THBD and VWF 1 0.02 1.71 0.16
120 INT231677 Binding of CD47 and THBS1 1 0.18 0 0.16
121 INT83512 F2 Negative_regulation of PLAU 1 0.27 0.57 0.16
122 INT109887 F2 Negative_regulation of F8 1 0.00 1.32 0.16
123 INT83513 Negative_regulation of SERPINC1 Negative_regulation of F2 1 0.16 0.64 0.16
124 INT83515 F2 Positive_regulation of PLAU 1 0.31 0.57 0.16
125 INT294207 Serpine1 Regulation of Gene_expression of Plat 1 0.50 0.92 0.16
126 INT83511 F2 Negative_regulation of PRH1 1 0.01 0.6 0.15
127 INT270416 PLAT Negative_regulation of Positive_regulation of PLG 1 0.00 0.48 0.15
128 INT37659 IGHG3 Negative_regulation of F2 1 0.06 0.79 0.15
129 INT240768 Binding of F2 and F13A1 1 0.07 2.25 0.15
130 INT252352 Binding of THBS1 and Sirpa 1 0.00 0.26 0.15
131 INT109886 F2 Negative_regulation of Serpinc1 1 0.00 1.18 0.15
132 INT319119 SERPINE1 Negative_regulation of Positive_regulation of PLG 1 0.11 1.56 0.15
133 INT188249 PLAT Positive_regulation of PLG 2 0.10 0.86 0.14
134 INT191001 F3 Positive_regulation of F2 1 0.00 0.62 0.14
135 INT180671 Binding of Plat and Regulation of Serpine1 1 0.16 0.06 0.14
136 INT11641 Binding of SERPINE1 and Serpinc1 1 0.00 0.78 0.13
137 INT174917 Negative_regulation of PLG Negative_regulation of Positive_regulation of FUT1 1 0.01 0.68 0.13
138 INT11632 Binding of SERPINE1 and TAT 1 0.11 0.78 0.13
139 INT300513 Binding of Serpine1 and Vtn 1 0.17 2.27 0.13
140 INT107005 F2 Positive_regulation of PRSS1 1 0.00 0.28 0.13
141 INT321404 Positive_regulation of MAP3K5 Positive_regulation of Gene_expression of SERPINE1 1 0.02 2.2 0.12
142 INT99737 Serpinf2 Negative_regulation of Localization of SERPINE1 1 0.00 0.24 0.12
143 INT99732 Serpinf2 Negative_regulation of PLG 1 0.01 0.24 0.12
144 INT213144 TIMP1 Negative_regulation of THBD 1 0.04 1.16 0.12
145 INT213147 DAK Negative_regulation of THBD 1 0.00 1.16 0.12
146 INT294208 Gene_expression of Serpine1 Negative_regulation of Plat 1 0.47 0.94 0.12
147 INT253772 Binding of THBD and Hmgb1 1 0.05 0.95 0.12
148 INT253775 Negative_regulation of Binding of THBD and Hmgb1 1 0.06 0.69 0.12
149 INT307075 Tbxas1 Negative_regulation of Negative_regulation of PLG 1 0.01 1.22 0.11
150 INT195710 SERPINC1 Positive_regulation of F2 1 0.08 0.69 0.11
151 INT305002 Binding of HIF1A and SERPINE1 1 0.07 1.17 0.11
152 INT195711 Negative_regulation of SERPINC1 Positive_regulation of F2 1 0.08 0.7 0.11
153 INT232017 F12 Positive_regulation of PLG 1 0.03 0.52 0.11
154 INT22670 PLAT Positive_regulation of SERPINE1 1 0.03 0.1 0.1
155 INT246478 Binding of SERPINE1 and ANGPTL5 1 0.01 1.32 0.1
156 INT294450 KLK4 Negative_regulation of SERPINE1 1 0.01 0 0.1
157 INT8673 Binding of F2 and F8 1 0.08 0.48 0.1
158 INT294439 KLK4 Negative_regulation of THBS1 1 0.01 0 0.1
159 INT22672 Positive_regulation of Binding of SERPINE1 and PLAT 1 0.03 0.1 0.1
160 INT8672 Positive_regulation of Binding of F2 and F8 1 0.11 0.48 0.1
161 INT158615 Binding of Serpine1 and Plaur 1 0.04 0.38 0.1
162 INT8675 Positive_regulation of Binding of F2 and F3 2 0.17 0.43 0.09
163 INT8671 Binding of F2 and F3 2 0.13 0.42 0.09
164 INT158614 Negative_regulation of Binding of Serpine1 and Vtn 1 0.03 0.48 0.09
165 INT348686 Plg Positive_regulation of Protein_catabolism of Ecm1 1 0.02 0.17 0.09
166 INT232010 PLG Positive_regulation of TRGC1 1 0.08 0.51 0.09
167 INT230746 Crp Positive_regulation of Localization of Serpine1 1 0.16 0.27 0.09
168 INT61217 Negative_regulation of PRTN3 Negative_regulation of F2 1 0.01 0.16 0.08
169 INT348167 Thbs1 Positive_regulation of RAC1 1 0.04 0.71 0.08
170 INT195777 THBD Positive_regulation of PROC 1 0.00 1.26 0.08
171 INT199031 Binding of ALB and F2 1 0.05 1.78 0.08
172 INT239237 TCN2 Positive_regulation of Gene_expression of Serpine1 1 0.00 0.68 0.08
173 INT253774 THBD Regulation of F2 1 0.00 0.61 0.08
174 INT294220 INCENP Positive_regulation of Gene_expression of Serpine1 1 0.00 0.41 0.08
175 INT232011 SERPING1 Regulation of Negative_regulation of SERPINE1 1 0.01 0.45 0.07
176 INT247079 Gene_expression of PLAT Positive_regulation of Gene_expression of PLG 1 0.36 0.3 0.07
177 INT348168 Thbs1 Positive_regulation of PIK3CD 1 0.00 0.65 0.07
178 INT58649 Binding of INS and Serpine1 1 0.01 1.64 0.07
179 INT57268 SERPINE1 Positive_regulation of SERPINC1 1 0.07 0.94 0.07
180 INT122480 Binding of SERPINE1 and PLAU 4 0.40 2.75 0.06
181 INT191002 F2 Positive_regulation of Gene_expression of IL8 1 0.02 0.46 0.06
182 INT259635 Plau Positive_regulation of PLG 1 0.13 0.22 0.06
183 INT58586 IFNG Positive_regulation of Gene_expression of PLG 1 0.41 0.38 0.06
184 INT203732 Thbs1 Regulation of Gene_expression of Ppara 1 0.33 0.94 0.05
185 INT344703 Hdl1 Negative_regulation of Gene_expression of Serpine1 1 0.07 1.26 0.05
186 INT341535 F2RL1 Positive_regulation of Gene_expression of THBS1 1 0.28 0.75 0.04
187 INT279895 Binding of ABCC6 and USF1 1 0.31 0.8 0.04
188 INT245833 Plg Negative_regulation of VEGFA 1 0.05 2.21 0.04
189 INT240769 Positive_regulation of Binding of F13A1 and PLG 1 0.02 0.9 0.04
190 INT245826 Plg Regulation of Gene_expression of Serpinf1 1 0.09 1.57 0.04
191 INT328498 Sumo1 Positive_regulation of Plg 1 0.07 0.61 0.04
192 INT213037 Hdl1 Positive_regulation of Gene_expression of Serpine1 1 0.19 1.19 0.04
193 INT180955 PLG Regulation of Positive_regulation of TIMP1 1 0.21 0.38 0.04
194 INT279899 Binding of HSD11B1 and USF1 1 0.31 0.79 0.04
195 INT180956 PLG Regulation of Positive_regulation of MMP13 1 0.32 0.38 0.04
196 INT323675 Binding of THBD and BDNF-AS 1 0.02 2.45 0.04
197 INT279903 Binding of EMR1 and USF1 1 0.01 2.24 0.04
198 INT245825 Plg Positive_regulation of Gene_expression of Serpinf1 1 0.21 1.01 0.04
199 INT323674 Binding of TFPI and THBD 1 0.02 2.45 0.04
200 INT207997 Bel Regulation of Gene_expression of Plg 1 0.00 0 0.04

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of fibrinolysis. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of fibrinolysis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT11361 Gene_expression of SERPINE1 183 0.78 136.45 27.97
2 INT11636 Positive_regulation of SERPINE1 85 0.69 68.73 14.8
3 INT15684 Positive_regulation of Serpine1 65 0.70 43.51 13.67
4 INT15921 Positive_regulation of Serpine1 85 0.68 81.24 13.4
5 INT2129 Positive_regulation of F2 83 0.70 58.95 12.63
6 INT20102 Gene_expression of Serpine1 102 0.78 65.99 12.61
7 INT13287 Gene_expression of Cpb2 27 0.56 7.84 11.95
8 INT18334 Positive_regulation of Cpb2 24 0.69 2.98 11.22
9 INT4498 Gene_expression of F2 83 0.65 57.4 10.8
10 INT2378 Negative_regulation of SERPINE1 47 0.59 34.55 9.9
11 INT15918 Gene_expression of Serpine1 60 0.62 41.73 7.72
12 INT17501 Negative_regulation of F2 70 0.58 32.23 7.51
13 INT10145 Gene_expression of Plg 28 0.62 12.68 7.46
14 INT50990 Regulation of Cpb2 12 0.37 2.71 7.07
15 INT16389 Gene_expression of Plg 80 0.67 36.88 6.74
16 INT10610 Negative_regulation of Plg 22 0.40 11.81 6.74
17 INT117142 Gene_expression of Thbs1 58 0.72 45.02 6.51
18 INT4561 Gene_expression of PLG 32 0.75 17.59 6.21
19 INT11360 Localization of SERPINE1 41 0.80 33.98 5.61
20 INT15941 Negative_regulation of Serpine1 42 0.58 21.07 4.95
21 INT15920 Regulation of Serpine1 34 0.42 17.36 4.89
22 INT12104 Positive_regulation of PLG 45 0.68 28.94 4.81
23 INT9842 Binding of F2 36 0.47 22.79 4.42
24 INT11354 Regulation of Gene_expression of SERPINE1 11 0.61 8.66 4.42
25 INT11635 Positive_regulation of Gene_expression of SERPINE1 35 0.68 24.57 4.26
26 INT11634 Regulation of SERPINE1 24 0.62 20.06 4.26
27 INT16478 Positive_regulation of Plg 29 0.45 18.07 4.07
28 INT17324 Negative_regulation of Plg 26 0.38 13.5 4.05
29 INT17548 Negative_regulation of Serpine1 30 0.57 24.69 3.93
30 INT78737 Positive_regulation of Gene_expression of Cpb2 5 0.38 1.77 3.84
31 INT16644 Positive_regulation of Plg 16 0.60 6.38 3.62
32 INT16263 Regulation of Serpine1 13 0.45 5.24 3.6
33 INT25344 Localization of Plg 10 0.57 5 3.27
34 INT93343 Gene_expression of Cpb2 10 0.58 4.63 3.24
35 INT16390 Regulation of Plg 13 0.48 6.72 3.2
36 INT14447 Localization of F2 20 0.79 12.77 2.67
37 INT71933 Positive_regulation of Gene_expression of F2 19 0.56 14.24 2.53
38 INT137135 Gene_expression of THBS1 28 0.75 11.55 2.45
39 INT80329 Positive_regulation of THBD 12 0.47 20.96 2.45
40 INT104041 Positive_regulation of Cpb2 7 0.59 2.88 2.39
41 INT22679 Binding of SERPINE1 25 0.36 17.33 2.36
42 INT4560 Protein_catabolism of PLG 18 0.96 11.64 2.32
43 INT111922 Binding of Cpb2 3 0.41 3.12 2.3
44 INT15922 Positive_regulation of Positive_regulation of Serpine1 6 0.31 8.34 2.16
45 INT17268 Localization of PLG 9 0.78 11.71 2.06
46 INT46109 Binding of SERPINF2 6 0.37 1.08 2.06
47 INT50896 Negative_regulation of Cpb2 6 0.37 0.6 2.01
48 INT35146 Negative_regulation of PLG 27 0.57 17.63 1.98
49 INT71115 Positive_regulation of Gene_expression of Serpine1 20 0.70 15.32 1.97
50 INT130364 Positive_regulation of Thbs1 7 0.62 7.73 1.97
51 INT59283 Positive_regulation of Gene_expression of Plg 6 0.25 2.36 1.97
52 INT23188 Localization of Serpine1 22 0.79 16.06 1.96
53 INT17326 Binding of Plg 14 0.43 11.72 1.94
54 INT48722 Negative_regulation of Gene_expression of SERPINE1 12 0.43 7.66 1.85
55 INT60337 Positive_regulation of THBS1 8 0.46 4.69 1.83
56 INT16391 Regulation of Serpinf2 5 0.03 4.22 1.82
57 INT48720 Transcription of SERPINE1 11 0.68 4.76 1.67
58 INT14405 Gene_expression of SERPINF2 14 0.65 3 1.64
59 INT88667 Negative_regulation of Gene_expression of F2 11 0.41 5.53 1.62
60 INT14835 Regulation of CPB2 1 0.37 1.79 1.48
61 INT12035 Regulation of F2 21 0.45 12.66 1.47
62 INT14404 Negative_regulation of SERPINF2 11 0.47 3.15 1.47
63 INT16388 Protein_catabolism of Plg 6 0.79 3.46 1.4
64 INT157067 Regulation of Regulation of Cpb2 2 0.22 1.29 1.39
65 INT17325 Negative_regulation of Protein_catabolism of Plg 1 0.32 0 1.37
66 INT24685 Localization of Serpine1 12 0.59 7.76 1.32
67 INT41381 Positive_regulation of Gene_expression of Plg 8 0.44 3.29 1.3
68 INT128061 Negative_regulation of Gene_expression of Serpine1 16 0.43 13.13 1.29
69 INT288546 Regulation of Positive_regulation of THBS1 1 0.36 2.65 1.27
70 INT155992 Gene_expression of THBD 16 0.66 17 1.24
71 INT138343 Positive_regulation of Localization of F2 5 0.41 5.06 1.24
72 INT150805 Localization of THBS1 4 0.46 2.88 1.23
73 INT18422 Regulation of Plg 6 0.45 1.71 1.22
74 INT20100 Binding of Serpine1 16 0.29 6.78 1.18
75 INT191586 Localization of THBD 7 0.58 9.44 1.17
76 INT15919 Positive_regulation of Gene_expression of Serpine1 6 0.41 4.5 1.15
77 INT203729 Binding of Thbs1 1 0.27 3.83 1.1
78 INT16393 Gene_expression of Serpinf2 4 0.08 3.39 1.09
79 INT5643 Positive_regulation of SERPINF2 3 0.35 0.94 1.09
80 INT130928 Positive_regulation of Gene_expression of Thbs1 7 0.62 5.62 1.08
81 INT111923 Regulation of Cpb2 1 0.33 1.3 1.08
82 INT54137 Positive_regulation of Positive_regulation of Serpine1 4 0.70 0.79 1.06
83 INT99767 Regulation of THBS1 18 0.42 11.51 1.03
84 INT174273 Positive_regulation of Binding of F2 3 0.08 2.99 1.02
85 INT101841 Localization of SERPINF2 4 0.68 1.27 1.01
86 INT20156 Positive_regulation of Negative_regulation of Serpine1 4 0.49 2.89 0.97
87 INT169235 Negative_regulation of USF1 4 0.37 2.69 0.91
88 INT16479 Positive_regulation of Serpinf2 2 0.05 1.2 0.9
89 INT97768 Positive_regulation of Gene_expression of PLG 5 0.49 2.49 0.89
90 INT35318 Binding of CPB2 2 0.02 0 0.88
91 INT35141 Regulation of PLG 6 0.44 2.64 0.85
92 INT44221 Negative_regulation of CPB2 3 0.03 0.46 0.85
93 INT48717 Positive_regulation of Localization of SERPINE1 6 0.66 2.64 0.83
94 INT160993 Negative_regulation of Cpb2 2 0.18 1.68 0.83
95 INT83577 Negative_regulation of Gene_expression of Cpb2 1 0.35 0 0.81
96 INT73030 Regulation of SERPINF2 10 0.39 5.69 0.8
97 INT30926 Regulation of Gene_expression of Plg 11 0.45 2.14 0.78
98 INT112336 Binding of Serpine1 8 0.41 4.62 0.78
99 INT130363 Localization of Thbs1 9 0.75 4.99 0.76
100 INT118669 Binding of Cpb2 4 0.31 0.97 0.76
101 INT198669 Binding of THBD 5 0.10 4.45 0.75
102 INT138606 Negative_regulation of Positive_regulation of F2 2 0.12 0.54 0.74
103 INT79169 Binding of PLG 10 0.47 5.88 0.72
104 INT13702 Protein_catabolism of Plg 4 0.12 0.88 0.69
105 INT11362 Regulation of Localization of SERPINE1 3 0.39 1.55 0.69
106 INT83194 Binding of APOH 4 0.17 3.92 0.66
107 INT23348 Negative_regulation of Serpinf2 8 0.38 3.02 0.65
108 INT157066 Regulation of Gene_expression of Cpb2 1 0.22 0.47 0.64
109 INT16392 Protein_catabolism of Serpinf2 1 0.03 1.38 0.64
110 INT40281 Localization of CPB2 1 0.02 0.35 0.64
111 INT168000 Protein_catabolism of F2 6 0.63 2.19 0.63
112 INT189586 Regulation of THBD 5 0.17 5.15 0.61
113 INT252993 Negative_regulation of THBS1 8 0.55 6.93 0.59
114 INT142625 Negative_regulation of Localization of SERPINF2 1 0.31 0.16 0.59
115 INT70971 Negative_regulation of Positive_regulation of SERPINE1 3 0.40 2.65 0.58
116 INT59012 Negative_regulation of Positive_regulation of Cpb2 1 0.37 0 0.58
117 INT117145 Negative_regulation of Gene_expression of Thbs1 11 0.43 5.67 0.57
118 INT46340 Positive_regulation of Negative_regulation of Plg 2 0.15 1.71 0.54
119 INT150808 Negative_regulation of Localization of THBS1 1 0.25 0.5 0.53
120 INT20099 Regulation of Positive_regulation of Serpine1 2 0.40 1.75 0.52
121 INT58591 Negative_regulation of Positive_regulation of PLG 4 0.42 2.46 0.51
122 INT320172 Negative_regulation of Binding of F2 2 0.41 1.92 0.5
123 INT96864 Localization of Plg 7 0.67 2.07 0.48
124 INT151903 Positive_regulation of Positive_regulation of PLG 3 0.45 1.53 0.48
125 INT58015 Regulation of Gene_expression of Serpine1 3 0.41 2.61 0.47
126 INT56094 Protein_catabolism of SERPINE1 2 0.61 1.66 0.47
127 INT268576 Positive_regulation of Gene_expression of THBS1 2 0.64 2.26 0.47
128 INT35435 Negative_regulation of Positive_regulation of Serpine1 5 0.42 2.26 0.46
129 INT17269 Negative_regulation of Localization of PLG 1 0.03 0.54 0.45
130 INT20101 Regulation of Positive_regulation of Serpine1 1 0.10 0.94 0.44
131 INT158577 Negative_regulation of Gene_expression of Plg 7 0.17 3.36 0.43
132 INT203728 Regulation of Binding of Thbs1 1 0.33 2.76 0.42
133 INT133379 Negative_regulation of APOH 1 0.07 0.09 0.42
134 INT203726 Regulation of Thbs1 2 0.33 1.41 0.41
135 INT18335 Positive_regulation of Positive_regulation of Cpb2 1 0.28 0 0.4
136 INT162049 Phosphorylation of F2 3 0.47 0.99 0.39
137 INT39640 Negative_regulation of Gene_expression of Plg 2 0.25 1.13 0.39
138 INT126530 Negative_regulation of Positive_regulation of Serpine1 3 0.43 2.62 0.38
139 INT48721 Negative_regulation of Localization of SERPINE1 3 0.43 2.4 0.38
140 INT92242 Binding of Plg 2 0.32 1.09 0.37
141 INT130927 Negative_regulation of Thbs1 19 0.59 3.72 0.36
142 INT187606 Negative_regulation of Gene_expression of Serpine1 3 0.05 1.78 0.36
143 INT161436 Transcription of F2 2 0.69 1.21 0.36
144 INT81221 Positive_regulation of APOH 1 0.02 1.24 0.36
145 INT96865 Regulation of Positive_regulation of Plg 1 0.01 0.05 0.36
146 INT200606 Regulation of Gene_expression of Serpine1 4 0.38 2.07 0.35
147 INT274379 Negative_regulation of Binding of SERPINE1 1 0.03 0.91 0.33
148 INT172783 Regulation of Localization of Serpine1 3 0.30 3.83 0.32
149 INT130344 Gene_expression of APOH 3 0.34 2.87 0.32
150 INT152276 Regulation of Positive_regulation of PLG 2 0.44 1.53 0.32
151 INT83195 Regulation of Binding of APOH 1 0.13 0.88 0.31
152 INT162051 Positive_regulation of Phosphorylation of F2 1 0.29 0.99 0.3
153 INT99739 Protein_catabolism of Serpine1 4 0.87 1.71 0.29
154 INT212382 Positive_regulation of USF1 2 0.50 3.14 0.27
155 INT180969 Positive_regulation of Protein_catabolism of PLG 1 0.36 0.47 0.27
156 INT295320 Positive_regulation of Localization of THBD 1 0.26 1.31 0.27
157 INT162802 Regulation of Gene_expression of F2 3 0.37 1.56 0.26
158 INT48719 Negative_regulation of Transcription of SERPINE1 1 0.42 0.17 0.26
159 INT127616 Positive_regulation of CPB2 3 0.44 0.72 0.24
160 INT180280 Positive_regulation of Phosphorylation of SERPINE1 2 0.48 0 0.24
161 INT180281 Phosphorylation of SERPINE1 2 0.78 0 0.24
162 INT200522 Negative_regulation of Negative_regulation of PLG 2 0.41 1.53 0.24
163 INT202186 Negative_regulation of Phosphorylation of SERPINE1 1 0.41 0 0.24
164 INT130368 Transcription of Thbs1 2 0.69 1.39 0.23
165 INT153877 Positive_regulation of Binding of Plg 1 0.44 0.41 0.23
166 INT130360 Positive_regulation of Transcription of Thbs1 1 0.46 1.41 0.23
167 INT125772 Positive_regulation of Negative_regulation of Serpine1 1 0.42 0.4 0.22
168 INT216887 Positive_regulation of Localization of Plg 1 0.04 0.13 0.22
169 INT152680 Negative_regulation of THBD 3 0.29 1.87 0.21
170 INT100870 Positive_regulation of Binding of SERPINE1 2 0.49 1.24 0.21
171 INT222635 Gene_expression of Thbs1 4 0.39 15.2 0.2
172 INT48723 Regulation of Transcription of SERPINE1 1 0.27 0.26 0.2
173 INT125773 Transcription of Serpine1 4 0.53 2.35 0.19
174 INT178504 Positive_regulation of Localization of THBS1 2 0.05 1.9 0.19
175 INT25345 Negative_regulation of Localization of Plg 1 0.08 0.81 0.19
176 INT230983 Transcription of Cpb2 1 0.30 0 0.19
177 INT45721 Transcription of Plg 1 0.20 0.16 0.18
178 INT94854 Regulation of Negative_regulation of F2 1 0.11 0.18 0.18
179 INT25009 Regulation of Localization of Serpine1 2 0.36 0.15 0.17
180 INT270426 Regulation of Binding of SERPINE1 1 0.06 0.42 0.17
181 INT231474 Binding of THBS1 4 0.34 2.04 0.16
182 INT82636 Negative_regulation of Localization of Serpine1 1 0.29 1.01 0.16
183 INT212989 Negative_regulation of Localization of Serpine1 1 0.26 2.2 0.16
184 INT212957 Positive_regulation of Localization of Serpine1 2 0.50 1.89 0.15
185 INT348150 Binding of Thbs1 1 0.24 2.06 0.15
186 INT284156 Positive_regulation of Negative_regulation of F2 1 0.01 1.71 0.15
187 INT67181 Positive_regulation of Positive_regulation of SERPINE1 3 0.49 3.02 0.14
188 INT39633 Negative_regulation of Positive_regulation of Plg 2 0.22 0.4 0.14
189 INT250576 Gene_expression of USF1 3 0.77 18.99 0.13
190 INT79414 Binding of Serpinf2 1 0.24 0.35 0.13
191 INT119931 Positive_regulation of Positive_regulation of Cpb2 1 0.05 0.44 0.13
192 INT145018 Binding of USF1 4 0.42 15.42 0.11
193 INT305016 Positive_regulation of Negative_regulation of SERPINE1 1 0.10 1.13 0.11
194 INT216835 Positive_regulation of Localization of Plg 1 0.03 0.27 0.11
195 INT200599 Positive_regulation of Positive_regulation of Plg 3 0.07 2.11 0.1
196 INT348149 Regulation of Gene_expression of Thbs1 1 0.31 1.94 0.1
197 INT348145 Localization of Thbs1 1 0.41 6.72 0.1
198 INT28108 Protein_catabolism of SERPINF2 1 0.96 0 0.1
199 INT277070 Negative_regulation of Negative_regulation of SERPINE1 1 0.12 0.55 0.1
200 INT51990 Transcription of Serpine1 3 0.45 2.01 0.09
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