GO:0051920

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Name peroxiredoxin activity
Categary Function
Go Slim No
Go Link GO:0051920
Unique Molecular Interactions 20
Total Molecular Interactions 24
Total Single Events 98
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for peroxiredoxin activity. They are ordered first by their pain relevance and then by number of times they were reported for peroxiredoxin activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT353285 Prdx2 Regulation of Gene_expression of Col1a2 1 0.02 0.73 0.21
2 INT208264 Park7 Negative_regulation of Pten 1 0.16 1.16 0.15
3 INT204996 Binding of Park7 and Pink1 2 0.34 1.09 0.11
4 INT273288 Psen1 Regulation of Prdx2 1 0.01 0.7 0.06
5 INT353284 Prdx2 Negative_regulation of Gene_expression of Smad2 1 0.16 0.07 0.05
6 INT143993 Prdx2 Positive_regulation of Atp13a4 1 0.00 0 0.05
7 INT353289 Prdx2 Negative_regulation of Positive_regulation of Smad2 1 0.18 0.17 0.04
8 INT353293 Prdx2 Negative_regulation of Localization of Smad2 1 0.16 0 0.04
9 INT353287 Prdx2 Positive_regulation of Phosphorylation of Smad7 1 0.22 0.06 0.03
10 INT353291 Prdx2 Positive_regulation of Smad7 1 0.31 0.06 0.03
11 INT353286 Prdx2 Positive_regulation of Phosphorylation of Smad2 1 0.24 0.06 0.03
12 INT353283 Prdx2 Positive_regulation of Phosphorylation of Tgif1 1 0.10 0.06 0.03
13 INT353292 Prdx2 Positive_regulation of Tgif1 1 0.10 0.06 0.03
14 INT354622 CTSB Regulation of PRDX5 1 0.00 0.38 0
15 INT317301 Binding of Park2 and Park7 1 0.36 0.62 0
16 INT317316 Park7 Positive_regulation of Protein_catabolism of Hmbs 1 0.11 0.68 0
17 INT317324 Park7 Positive_regulation of Protein_catabolism of SNCAIP 1 0.38 0.69 0
18 INT317308 Binding of Park7 and Mul1 1 0.01 0.62 0
19 INT349296 Binding of CSF2 and PARK7 1 0.24 1.24 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for peroxiredoxin activity. They are ordered first by their pain relevance and then by number of times they were reported in peroxiredoxin activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT108250 Regulation of Prdx2 5 0.25 2.02 2.08
2 INT108249 Negative_regulation of Prdx2 3 0.32 1.85 1.36
3 INT164706 Positive_regulation of Park7 2 0.50 2.28 1.28
4 INT108243 Positive_regulation of Prdx2 3 0.34 0.85 0.95
5 INT193672 Gene_expression of Prdx2 3 0.50 2.75 0.64
6 INT171928 Gene_expression of PRDX5 1 0.07 1.24 0.33
7 INT349301 Negative_regulation of PARK7 1 0.41 3.44 0.26
8 INT143991 Gene_expression of Prdx2 5 0.61 1.54 0.22
9 INT353278 Binding of Prdx2 1 0.21 0.05 0.18
10 INT353270 Regulation of Binding of Prdx2 1 0.25 0.05 0.18
11 INT353274 Transcription of Prdx2 1 0.39 0.51 0.16
12 INT181912 Binding of PRDX5 1 0.05 0.68 0.15
13 INT353264 Negative_regulation of Negative_regulation of Prdx2 1 0.24 0.45 0.15
14 INT281868 Negative_regulation of Park7 1 0.00 1.69 0.14
15 INT349300 Gene_expression of PARK7 1 0.75 8.65 0.12
16 INT204986 Gene_expression of Park7 5 0.38 5.48 0.1
17 INT173981 Gene_expression of Park7 2 0.56 0.73 0.1
18 INT193676 Positive_regulation of Gene_expression of Prdx2 2 0.06 1.31 0.09
19 INT243711 Binding of Park7 3 0.25 1.5 0.06
20 INT204990 Positive_regulation of Gene_expression of Park7 2 0.24 1.79 0.05
21 INT204973 Positive_regulation of Park7 2 0.23 1.62 0.03
22 INT143990 Regulation of Prdx2 1 0.22 0 0.03
23 INT204970 Localization of Park7 3 0.54 2.76 0
24 INT349303 Positive_regulation of Positive_regulation of PARK7 1 0.49 1 0
25 INT349298 Phosphorylation of PARK7 1 0.79 0.9 0
26 INT349304 Positive_regulation of PARK7 1 0.67 9.44 0
27 INT208272 Regulation of Gene_expression of Park7 1 0.19 0.27 0
28 INT349302 Localization of PARK7 1 0.78 3.09 0
29 INT349299 Binding of PARK7 1 0.41 1.86 0
30 INT190472 Regulation of PRDX5 1 0.44 0.69 0
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