GO:0051932

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Name synaptic transmission, GABAergic
Categary Process
Go Slim No
Go Link GO:0051932
Unique Molecular Interactions 38
Total Molecular Interactions 56
Total Single Events 499
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for synaptic transmission, GABAergic. They are ordered first by their pain relevance and then by number of times they were reported for synaptic transmission, GABAergic. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT136514 Binding of Grm1 and Grm5 4 0.12 1.8 3.9
2 INT140347 Binding of ATP1A2 and Cacna1a 1 0.11 2.88 2.73
3 INT74840 Binding of Cacna1a and Cacna1a 5 0.00 4.24 2.36
4 INT355251 Cacna1a Regulation of Gene_expression of Gabrg1 1 0.01 0.06 1.86
5 INT355249 Cacna1a Regulation of Gene_expression of Ltp 1 0.04 0.06 1.86
6 INT355254 Ltp Regulation of Cacna1a 1 0.04 0 1.58
7 INT74843 Binding of Cacna1a and Ea2 3 0.13 3.29 1.55
8 INT112033 Gabrb3 Positive_regulation of Plcg1 1 0.05 0.18 1.49
9 INT112034 Gabrb3 Positive_regulation of Pik3r1 1 0.08 0.18 1.48
10 INT355250 Ltp Regulation of Positive_regulation of Cacna1a 1 0.04 0 1.39
11 INT355253 Ltp Positive_regulation of Cacna1a 1 0.05 0 1.34
12 INT355252 Binding of Cacna1a and Cnr1 1 0.04 0 1.31
13 INT74841 Binding of Cacna1a and Ea2 2 0.01 2.33 1.27
14 INT108729 Binding of CACNA1A and Cacna1a 3 0.13 1.21 0.95
15 INT282139 Grm1 Regulation of Grip2 1 0.00 0.62 0.69
16 INT31416 Cacna1a Positive_regulation of Gene_expression of Gcg 1 0.03 0 0.65
17 INT282142 Grm1 Positive_regulation of Positive_regulation of Trib3 1 0.01 0.27 0.57
18 INT354986 Cacna1a Regulation of Localization of Mpo 1 0.01 1.15 0.49
19 INT354981 Cacna1a Negative_regulation of Gene_expression of Nos2 1 0.01 0.99 0.45
20 INT354984 Binding of Cacna1a and Tnf 1 0.01 0.83 0.4
21 INT158355 Cacna1a Regulation of Alox5 1 0.01 0.7 0.37
22 INT354985 Cacna1a Regulation of Nos2 1 0.01 0.73 0.34
23 INT354982 Cacna1a Regulation of Tnf 1 0.00 0.73 0.34
24 INT151258 Binding of Cacna1a and FCMTE1 1 0.00 0.57 0.3
25 INT142003 Binding of Cacna1a and Etax2 1 0.00 1.02 0.26
26 INT142004 Binding of Cacna1a and TGM6 1 0.00 1.02 0.26
27 INT356231 Binding of Gabrb3 and Gad1 1 0.32 1.25 0.23
28 INT71329 Cacna1a Regulation of Ea2 1 0.01 0.71 0.15
29 INT71328 Cacna1a Regulation of Atxn2 1 0.00 0.71 0.15
30 INT328143 Gabrb3 Positive_regulation of Ube3a 1 0.56 0.99 0.11
31 INT328146 Gabrb3 Negative_regulation of Ube3a 1 0.48 0.99 0.11
32 INT120559 Binding of Cacna1a and FCMTE1 1 0.02 0.25 0.1
33 INT354983 Cacna1a Regulation of Mpo 1 0.02 0.41 0.04
34 INT354987 Cacna1a Regulation of Localization of LDHA 1 0.00 0.23 0.03
35 INT261963 Binding of Cacna1a and Tgm2 1 0.08 1.19 0
36 INT250496 Gopc Regulation of Positive_regulation of Cacna1a 1 0.37 0 0
37 INT328141 Binding of Chrne and Gabrb3 1 0.41 0.08 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for synaptic transmission, GABAergic. They are ordered first by their pain relevance and then by number of times they were reported in synaptic transmission, GABAergic. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT66331 Gene_expression of Cacna1a 101 0.78 49.58 46.32
2 INT26698 Positive_regulation of Cacna1a 37 0.67 26.33 39.1
3 INT41487 Negative_regulation of Cacna1a 16 0.57 9.42 25.2
4 INT31136 Binding of Cacna1a 28 0.45 30.76 17.35
5 INT48055 Gene_expression of Grm1 27 0.78 14.29 17.01
6 INT30101 Regulation of Cacna1a 25 0.45 14.38 12.43
7 INT100919 Positive_regulation of Grm1 21 0.70 7.82 11.55
8 INT75765 Positive_regulation of Gene_expression of Cacna1a 17 0.70 17.51 10.91
9 INT91821 Binding of Cacna1a 16 0.48 13.1 6.37
10 INT113153 Regulation of Grm1 6 0.44 4.11 5.41
11 INT129508 Localization of Cacna1a 7 0.74 6.47 5.13
12 INT100920 Positive_regulation of Gene_expression of Grm1 7 0.70 5.88 4.87
13 INT91055 Negative_regulation of Grm1 7 0.45 5.14 4.87
14 INT110796 Positive_regulation of Positive_regulation of Cacna1a 1 0.49 0.51 4.84
15 INT82731 Transcription of Cacna1a 5 0.56 3.41 4.27
16 INT74814 Binding of Grm1 5 0.45 2.69 4.1
17 INT94045 Regulation of Cacna1a 5 0.42 3.56 3.33
18 INT85572 Gene_expression of Cacna1a 11 0.66 5.72 3.02
19 INT142940 Positive_regulation of Negative_regulation of Cacna1a 3 0.50 1.65 2.97
20 INT355244 Negative_regulation of Negative_regulation of Cacna1a 1 0.04 0 2.67
21 INT74361 Negative_regulation of Gabrb3 4 0.58 0.73 2.28
22 INT110795 Regulation of Positive_regulation of Cacna1a 2 0.26 0.65 2.07
23 INT98927 Localization of Grm1 4 0.71 0.42 1.97
24 INT354979 Positive_regulation of Localization of Cacna1a 2 0.05 0.86 1.79
25 INT355239 Negative_regulation of Positive_regulation of Cacna1a 1 0.04 0 1.79
26 INT71327 Localization of Cacna1a 3 0.60 2.51 1.7
27 INT74360 Gene_expression of Gabrb3 2 0.77 3.85 1.49
28 INT355242 Negative_regulation of Binding of Cacna1a 1 0.04 0.17 1.47
29 INT355245 Regulation of Localization of Cacna1a 1 0.04 0 1.43
30 INT152371 Regulation of Gene_expression of Grm1 2 0.42 0.54 1.4
31 INT90740 Negative_regulation of Cacna1a 3 0.23 1.43 1.38
32 INT82727 Positive_regulation of Transcription of Cacna1a 1 0.01 1.07 1.25
33 INT100921 Positive_regulation of Positive_regulation of Grm1 2 0.47 1.01 1.24
34 INT85571 Positive_regulation of Cacna1a 3 0.50 2.06 1.18
35 INT355243 Negative_regulation of Regulation of Cacna1a 1 0.04 0 1.16
36 INT321650 Negative_regulation of Gene_expression of Cacna1a 2 0.04 0.13 0.95
37 INT94046 Protein_catabolism of Cacna1a 1 0.70 0.83 0.9
38 INT223641 Transcription of Grm1 3 0.69 1.4 0.83
39 INT103336 Transcription of Cacna1a 2 0.69 1.17 0.68
40 INT353901 Negative_regulation of Negative_regulation of Grm1 1 0.40 0.67 0.61
41 INT91054 Negative_regulation of Gene_expression of Grm1 2 0.36 0.19 0.59
42 INT74362 Regulation of Gabrb3 1 0.28 0 0.58
43 INT86339 Positive_regulation of Gabrb3 1 0.14 0.14 0.51
44 INT99962 Positive_regulation of Gene_expression of Cacna1a 1 0.01 1.1 0.34
45 INT328133 Localization of Gabrb3 1 0.75 1.35 0.27
46 INT356219 Binding of Gabrb3 1 0.29 1.25 0.23
47 INT328139 Negative_regulation of Gene_expression of Gabrb3 1 0.43 0.1 0.15
48 INT223642 Negative_regulation of Transcription of Grm1 1 0.57 0.65 0.08
49 INT309389 Phosphorylation of Cacna1a 1 0.01 0.54 0.05
50 INT309386 Positive_regulation of Phosphorylation of Cacna1a 1 0.01 0.54 0.05
51 INT328126 Positive_regulation of Gene_expression of Gabrb3 1 0.50 1.08 0
52 INT328138 Protein_catabolism of Gabrb3 1 0.88 0 0
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