GO:0051938

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Name L-glutamate import
Categary Process
Go Slim No
Go Link GO:0051938
Unique Molecular Interactions 100
Total Molecular Interactions 145
Total Single Events 2214
Pain Genes Associated 11

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for L-glutamate import. They are ordered first by their pain relevance and then by number of times they were reported for L-glutamate import. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT142527 Binding of Slc1a2 and Slc1a3 2 0.31 0.12 2.13
2 INT352464 Gse1 Positive_regulation of Gene_expression of Slc1a3 1 0.05 1.55 1.83
3 INT187805 Ms18 Regulation of Positive_regulation of Slc1a3 1 0.26 0.87 1.12
4 INT250253 Binding of AQP4 and SLC1A2 1 0.30 2.95 1.09
5 INT297487 Negative_regulation of Slc1a2 Negative_regulation of Positive_regulation of Ltp 1 0.01 0.46 1.03
6 INT297486 Slc1a2 Negative_regulation of Positive_regulation of Ltp 1 0.01 0.45 1.02
7 INT250248 Binding of AQP4 and SLC1A3 1 0.11 1.55 0.77
8 INT74829 Oprd1 Regulation of Slc1a2 1 0.17 0 0.76
9 INT128276 ecs Regulation of Transcription of Slc17a7 1 0.01 0.29 0.65
10 INT127057 Ddc Positive_regulation of Gene_expression of Slc1a2 1 0.01 0.06 0.63
11 INT128275 Slc17a7 Positive_regulation of Transcription of Slc17a6 1 0.39 0.27 0.63
12 INT311766 INCENP Negative_regulation of Gene_expression of SLC1A3 1 0.04 0 0.55
13 INT311767 INS Negative_regulation of Gene_expression of SLC1A3 1 0.52 0 0.52
14 INT132242 NR3C1 Regulation of Gene_expression of Slc1a1 1 0.09 0.62 0.49
15 INT291384 Cntf Positive_regulation of Slc1a3 1 0.26 0.34 0.45
16 INT291387 Cntf Positive_regulation of Slc1a2 1 0.12 0.34 0.45
17 INT250251 Binding of SLC1A2 and SLC1A3 1 0.09 1.12 0.43
18 INT282505 Binding of ocd and Slc1a1 1 0.39 4.22 0.4
19 INT250250 Gene_expression of AQP4 Positive_regulation of Gene_expression of SLC1A2 1 0.37 1.1 0.39
20 INT64639 Slc1a1 Positive_regulation of Ddc 1 0.30 0.3 0.38
21 INT148515 Binding of Penk and Slc17a7 1 0.21 0 0.36
22 INT250252 Binding of SLC1A2 and GOPC 1 0.05 0.44 0.35
23 INT250254 Binding of SLC1A3 and GOPC 1 0.02 0.44 0.35
24 INT117789 Binding of CALCA and Slc17a7 1 0.09 0 0.35
25 INT291394 Gene_expression of HTT Negative_regulation of Gene_expression of Slc1a2 1 0.11 0.96 0.34
26 INT352461 Calca Regulation of Gene_expression of Slc1a3 1 0.03 0 0.27
27 INT352451 Gse1 Regulation of Slc1a3 1 0.01 0 0.27
28 INT352455 Gse1 Regulation of Gene_expression of Slc1a3 1 0.04 0 0.27
29 INT352449 Dusp1 Regulation of Gene_expression of Slc1a3 1 0.05 0 0.27
30 INT293505 Binding of Cnr1 and Slc17a7 1 0.11 0 0.23
31 INT305509 Slc17a7 Positive_regulation of Ex 1 0.05 0.09 0.23
32 INT309513 Binding of Xrcc6 and Htt 1 0.30 3.69 0.21
33 INT250241 SLC1A3 Positive_regulation of AQP4 1 0.13 0.21 0.16
34 INT250246 SLC1A2 Positive_regulation of AQP4 1 0.13 0.22 0.16
35 INT268733 Slc1a3 Regulation of Binding of Slc1a2 1 0.39 0.23 0.14
36 INT268735 Slc1a2 Regulation of Binding of Slc1a3 1 0.39 0.23 0.14
37 INT317162 Binding of Bdnf and Htt 1 0.51 0.2 0.12
38 INT319315 Binding of Ap2a2 and Htt 1 0.28 0.64 0.11
39 INT250249 Binding of SLC1A2 and Positive_regulation of SLC1A3 1 0.12 0.69 0.08
40 INT250244 Binding of AQP4 and Positive_regulation of SLC1A3 1 0.14 0.69 0.08
41 INT198079 Ass1 Positive_regulation of Gene_expression of Slc1a3 1 0.01 0 0.07
42 INT250243 FCGR3A Regulation of Gene_expression of SLC1A2 1 0.00 0.78 0.06
43 INT250245 Binding of FCGR3A and SLC1A3 1 0.00 0.18 0.05
44 INT317181 Binding of Htt and Uts2r 1 0.04 0 0.05
45 INT306527 Binding of Htt and Aifm1 1 0.20 0.82 0.04
46 INT317161 Htt Regulation of Transcription of Bdnf 1 0.48 0.41 0.03
47 INT200311 Htt Positive_regulation of Rest 1 0.05 0.75 0.03
48 INT314397 Binding of Ptpn6 and Slc17a7 1 0.05 0 0
49 INT121179 Binding of Htt and Rest 1 0.07 0.45 0
50 INT309515 Xrcc6 Regulation of Gene_expression of Htt 1 0.32 0.08 0
51 INT121177 Binding of Bdnf and Htt 1 0.23 0.44 0
52 INT309521 PRKDC Regulation of Gene_expression of Htt 1 0.41 0.08 0
53 INT121180 Htt Negative_regulation of Bdnf 1 0.43 0.47 0
54 INT309519 Xrcc5 Regulation of Gene_expression of Htt 1 0.18 0.08 0
55 INT282502 Negative_regulation of Binding of ocd and Slc1a1 1 0.30 0.48 0
56 INT261893 Binding of Htt and Hap1 1 0.13 0.49 0
57 INT314399 Binding of Slc17a7 and Slc17a6 1 0.14 0 0
58 INT317163 Htt Regulation of Bdnf 1 0.29 0.19 0
59 INT309516 Htt Positive_regulation of Gene_expression of Xrcc6 1 0.49 0.06 0
60 INT121176 Htt Regulation of Bdnf 1 0.17 0.77 0
61 INT309509 Negative_regulation of Binding of Xrcc6 and Htt 1 0.31 0.41 0
62 INT309510 Htt Regulation of Gene_expression of Xrcc6 1 0.19 0.15 0
63 INT309508 Htt Negative_regulation of Binding of Xrcc6 1 0.31 0.48 0
64 INT309514 Positive_regulation of Binding of Xrcc6 and Htt 1 0.33 0 0
65 INT215341 Binding of Htt and Sp1 1 0.03 0.25 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for L-glutamate import. They are ordered first by their pain relevance and then by number of times they were reported in L-glutamate import. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT74826 Gene_expression of Slc1a2 131 0.78 61.83 100.84
2 INT96533 Gene_expression of Slc1a3 72 0.78 26.85 55.31
3 INT74827 Positive_regulation of Gene_expression of Slc1a2 52 0.70 26.54 50.63
4 INT127013 Negative_regulation of Slc1a3 37 0.54 14.16 43.97
5 INT99539 Positive_regulation of Slc1a2 25 0.67 5.46 23.38
6 INT99538 Gene_expression of Slc1a1 26 0.75 9.3 21.57
7 INT135673 Positive_regulation of Slc1a3 23 0.57 5.45 21.45
8 INT93485 Negative_regulation of Slc1a2 27 0.59 10.65 20.9
9 INT107930 Gene_expression of Slc17a7 39 0.78 6.53 18.86
10 INT96532 Negative_regulation of Gene_expression of Slc1a2 24 0.59 14.22 17.91
11 INT98110 Regulation of Gene_expression of Slc1a2 16 0.62 11.76 17.31
12 INT128013 Negative_regulation of Gene_expression of Slc1a3 20 0.59 10.65 16.13
13 INT98109 Regulation of Slc1a3 15 0.52 6.87 14.43
14 INT105194 Negative_regulation of Slc1a1 11 0.56 3.05 14.19
15 INT135674 Positive_regulation of Gene_expression of Slc1a3 11 0.62 5.21 13.61
16 INT182574 Localization of Slc1a3 10 0.73 5.47 11.44
17 INT74828 Regulation of Slc1a2 12 0.61 3.92 10.3
18 INT53063 Positive_regulation of Slc1a1 10 0.70 3.23 9.89
19 INT179753 Gene_expression of SLC1A2 28 0.59 13.72 8.71
20 INT139930 Gene_expression of Slc17a7 35 0.75 6.22 8.33
21 INT155680 Gene_expression of Slc1a3 22 0.66 6.76 7.23
22 INT127014 Negative_regulation of Negative_regulation of Slc1a3 6 0.54 2.11 6.98
23 INT179744 Negative_regulation of SLC1A2 16 0.45 12.32 6.14
24 INT136153 Binding of Slc1a3 7 0.40 2.71 6.01
25 INT135675 Positive_regulation of Negative_regulation of Slc1a3 4 0.45 0.38 5.87
26 INT135672 Negative_regulation of Positive_regulation of Slc1a3 4 0.38 0.33 5.49
27 INT165460 Gene_expression of SLC1A3 15 0.75 7.19 5.43
28 INT99536 Regulation of Gene_expression of Slc1a3 6 0.60 1.76 5.04
29 INT155681 Negative_regulation of Gene_expression of Slc1a3 5 0.36 2.26 4.86
30 INT124920 Positive_regulation of Negative_regulation of Slc1a2 4 0.58 0.06 4.69
31 INT132237 Negative_regulation of Gene_expression of Slc1a1 4 0.56 2.05 4.45
32 INT111055 Localization of Slc1a2 4 0.71 2.04 4.41
33 INT267678 Positive_regulation of Positive_regulation of Slc1a1 1 0.07 1.34 3.65
34 INT99535 Transcription of Slc1a2 6 0.72 1.31 3.46
35 INT105195 Positive_regulation of Negative_regulation of Slc1a1 2 0.40 0.48 3.4
36 INT124921 Negative_regulation of Negative_regulation of Slc1a1 3 0.56 0.67 3.36
37 INT132239 Localization of Slc1a1 4 0.77 1.93 3.27
38 INT187803 Negative_regulation of Localization of Slc1a3 1 0.23 1.24 3.2
39 INT115407 Transcription of Slc17a7 2 0.72 1.28 3.12
40 INT198076 Gene_expression of Slc1a1 13 0.73 2.41 3.07
41 INT179756 Positive_regulation of Gene_expression of SLC1A2 8 0.38 2.95 3.06
42 INT87314 Gene_expression of Htt 112 0.78 55.82 3.03
43 INT132240 Positive_regulation of Gene_expression of Slc1a1 2 0.66 0.62 2.96
44 INT155685 Regulation of Gene_expression of Slc1a3 2 0.50 0.77 2.85
45 INT124922 Negative_regulation of Negative_regulation of Slc1a2 2 0.35 0.07 2.79
46 INT128268 Positive_regulation of Gene_expression of Slc17a7 4 0.70 1.34 2.78
47 INT142525 Binding of Slc1a2 4 0.45 0.94 2.65
48 INT250283 Positive_regulation of SLC1A2 5 0.53 3.22 2.29
49 INT195110 Positive_regulation of Gene_expression of Slc1a3 5 0.44 2.88 2.27
50 INT179750 Negative_regulation of Gene_expression of SLC1A2 3 0.45 3.05 2.15
51 INT129505 Regulation of Slc17a7 5 0.37 1.09 2.11
52 INT99534 Regulation of Gene_expression of Slc1a1 2 0.48 1.67 2.01
53 INT179749 Regulation of SLC1A2 3 0.34 2.28 1.99
54 INT127053 Transcription of Slc1a3 4 0.43 0.8 1.9
55 INT128267 Positive_regulation of Transcription of Slc17a7 1 0.70 0.82 1.9
56 INT128269 Positive_regulation of Slc17a7 3 0.50 1.06 1.82
57 INT137518 Regulation of Slc1a1 2 0.47 0.74 1.82
58 INT165459 Positive_regulation of SLC1A3 3 0.49 1.08 1.73
59 INT128273 Regulation of Gene_expression of Slc17a7 3 0.62 0.82 1.72
60 INT137519 Binding of Slc1a1 2 0.29 0.68 1.7
61 INT99537 Positive_regulation of Transcription of Slc1a2 4 0.70 0.8 1.69
62 INT151271 Positive_regulation of Positive_regulation of Slc1a2 1 0.32 0 1.69
63 INT151270 Positive_regulation of Positive_regulation of Slc1a3 1 0.57 0 1.69
64 INT198066 Negative_regulation of Slc1a3 2 0.41 1.25 1.68
65 INT138294 Regulation of Negative_regulation of Slc1a3 1 0.29 0.17 1.62
66 INT155829 Negative_regulation of Protein_catabolism of Slc1a3 1 0.34 0.1 1.6
67 INT155828 Protein_catabolism of Slc1a3 1 0.80 0.1 1.6
68 INT165457 Negative_regulation of SLC1A3 3 0.42 1.46 1.56
69 INT179752 Positive_regulation of Gene_expression of SLC1A3 3 0.17 2.35 1.56
70 INT56439 Regulation of Positive_regulation of Slc1a1 3 0.32 1.65 1.47
71 INT179754 Regulation of Gene_expression of SLC1A2 3 0.34 0.93 1.32
72 INT187801 Negative_regulation of Binding of Slc1a3 1 0.26 0.25 1.26
73 INT255271 Positive_regulation of Gene_expression of Slc17a7 3 0.59 1.48 1.19
74 INT305488 Binding of Slc17a7 2 0.32 2.61 1.13
75 INT116213 Regulation of Transcription of Slc1a2 1 0.61 0.41 1.12
76 INT354246 Negative_regulation of Slc17a7 1 0.40 0.28 1.09
77 INT165458 Regulation of Gene_expression of SLC1A3 1 0.23 0.26 1.08
78 INT108997 Localization of Htt 28 0.77 3.76 1.07
79 INT187804 Positive_regulation of Localization of Slc1a3 1 0.26 0.84 1.06
80 INT179751 Negative_regulation of Gene_expression of SLC1A3 1 0.19 0.75 1.05
81 INT266292 Localization of Slc17a7 3 0.51 0.73 0.98
82 INT254875 Positive_regulation of Htt 10 0.47 4.07 0.96
83 INT198074 Positive_regulation of Gene_expression of Slc1a1 2 0.65 0.25 0.89
84 INT127051 Positive_regulation of Transcription of Slc1a3 2 0.14 0.37 0.89
85 INT191831 Positive_regulation of Slc1a3 6 0.49 3.66 0.87
86 INT154886 Gene_expression of Htt 18 0.76 15.51 0.82
87 INT352657 Transcription of SLC1A2 1 0.06 0.76 0.8
88 INT352660 Transcription of SLC1A3 1 0.05 0.76 0.8
89 INT198064 Negative_regulation of Gene_expression of Slc1a1 1 0.39 0.26 0.76
90 INT255276 Positive_regulation of Slc17a7 5 0.59 1.88 0.68
91 INT179748 Regulation of SLC1A3 1 0.15 0.09 0.66
92 INT128271 Regulation of Transcription of Slc17a7 1 0.45 0.29 0.64
93 INT268729 Negative_regulation of Positive_regulation of Slc1a2 2 0.40 0.89 0.63
94 INT98239 Negative_regulation of Htt 13 0.43 7.84 0.6
95 INT261850 Regulation of Positive_regulation of Slc17a7 1 0.10 0.49 0.58
96 INT287206 Regulation of Gene_expression of Htt 6 0.50 3.27 0.57
97 INT215340 Localization of Htt 10 0.61 5.12 0.55
98 INT287204 Protein_catabolism of Htt 6 0.99 2.8 0.53
99 INT119230 Negative_regulation of Htt 5 0.42 2.99 0.5
100 INT319282 Positive_regulation of Slc1a1 1 0.43 0.17 0.5
101 INT319255 Positive_regulation of Transcription of Slc1a1 1 0.65 0.17 0.48
102 INT319272 Transcription of Slc1a1 1 0.67 0.16 0.47
103 INT208888 Transcription of Slc17a7 1 0.17 0 0.46
104 INT148512 Binding of Slc17a7 2 0.31 0 0.45
105 INT243418 Binding of Htt 14 0.30 5.94 0.44
106 INT165597 Positive_regulation of Htt 8 0.60 4.27 0.44
107 INT250276 Localization of SLC1A2 1 0.61 2.4 0.44
108 INT352656 Positive_regulation of Transcription of SLC1A2 1 0.04 0.39 0.43
109 INT352659 Positive_regulation of Transcription of SLC1A3 1 0.04 0.39 0.43
110 INT198072 Positive_regulation of Localization of Slc1a1 1 0.40 0.1 0.39
111 INT198070 Localization of Slc1a1 1 0.63 0.1 0.39
112 INT132864 Binding of Htt 15 0.46 2.34 0.38
113 INT198078 Positive_regulation of Negative_regulation of Slc1a3 1 0.40 0.15 0.38
114 INT150431 Regulation of Transcription of Slc1a3 1 0.10 0.33 0.37
115 INT198069 Regulation of Gene_expression of Slc1a1 1 0.56 0.12 0.36
116 INT287207 Regulation of Protein_catabolism of Htt 3 0.45 1.73 0.35
117 INT198071 Regulation of Slc1a3 1 0.36 0.08 0.35
118 INT313997 Regulation of Regulation of Slc1a2 1 0.06 0.66 0.29
119 INT254877 Positive_regulation of Gene_expression of Htt 15 0.64 6.29 0.28
120 INT117786 Localization of Slc17a7 2 0.17 0 0.28
121 INT250277 Regulation of Localization of SLC1A2 1 0.34 0.99 0.25
122 INT250278 Binding of SLC1A2 1 0.28 1.52 0.24
123 INT305493 Negative_regulation of Gene_expression of Slc17a7 1 0.41 0.1 0.24
124 INT287205 Regulation of Htt 5 0.45 3.56 0.22
125 INT198077 Regulation of Slc1a1 1 0.24 0.07 0.18
126 INT206487 Binding of SLC1A3 2 0.36 0.21 0.17
127 INT198075 Binding of Slc1a1 2 0.35 1.02 0.14
128 INT268732 Negative_regulation of Binding of Slc1a2 1 0.41 0.23 0.14
129 INT268731 Regulation of Binding of Slc1a2 1 0.26 0.23 0.14
130 INT255275 Negative_regulation of Positive_regulation of Slc17a7 1 0.26 0.08 0.13
131 INT270125 Transcription of Slc1a1 1 0.10 1.76 0.09
132 INT253783 Negative_regulation of Slc17a7 2 0.18 0 0.08
133 INT287203 Negative_regulation of Gene_expression of Htt 7 0.37 5.08 0.07
134 INT261890 Positive_regulation of Gene_expression of Htt 1 0.43 0.85 0.06
135 INT198065 Binding of Slc1a3 3 0.30 0 0.05
136 INT317175 Positive_regulation of Localization of Htt 1 0.48 0 0.05
137 INT266291 Positive_regulation of Localization of Slc17a7 1 0.34 0.07 0.05
138 INT306521 Transcription of Htt 1 0.69 4.13 0.05
139 INT277525 Transcription of Slc1a3 1 0.59 0.09 0.05
140 INT250271 Localization of SLC1A3 1 0.20 0.77 0.04
141 INT270126 Positive_regulation of Transcription of Slc1a1 1 0.10 0.8 0.04
142 INT331204 Negative_regulation of Binding of Htt 1 0.04 0.64 0.04
143 INT250268 Regulation of Localization of SLC1A3 1 0.12 0.77 0.04
144 INT261891 Negative_regulation of Gene_expression of Htt 1 0.37 1.12 0.04
145 INT154887 Transcription of Htt 3 0.66 0 0
146 INT261886 Regulation of Htt 2 0.43 2.06 0
147 INT313014 Positive_regulation of Binding of Htt 2 0.13 0.91 0
148 INT341938 Positive_regulation of Negative_regulation of Htt 1 0.07 0.65 0
149 INT254883 Negative_regulation of Positive_regulation of Htt 1 0.05 1.14 0
150 INT317177 Negative_regulation of Transcription of Htt 1 0.41 0 0
151 INT234093 Regulation of Slc17a7 1 0.15 0 0
152 INT309469 Negative_regulation of Localization of Htt 1 0.34 0.13 0
153 INT253782 Negative_regulation of Localization of Slc17a7 1 0.03 0 0
154 INT317170 Regulation of Binding of Htt 1 0.43 0 0
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