GO:0051964

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Name negative regulation of synapse assembly
Categary Process
Go Slim No
Go Link GO:0051964
Unique Molecular Interactions 55
Total Molecular Interactions 76
Total Single Events 724
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of synapse assembly. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of synapse assembly. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT116930 OPRK1 Positive_regulation of Binding of PTK2 1 0.28 0.35 0.93
2 INT116109 VEGFA Positive_regulation of PTK2 1 0.13 0.3 0.83
3 INT111936 Binding of PIK3CA and PTK2 1 0.19 0.67 0.65
4 INT111937 Binding of PIK3CG and PTK2 1 0.08 0.67 0.64
5 INT116932 PTK2 Negative_regulation of Positive_regulation of MAPK8 1 0.35 0.17 0.48
6 INT116935 Positive_regulation of OPRK1 Positive_regulation of Phosphorylation of PTK2 1 0.39 0.17 0.47
7 INT116939 OPRK1 Positive_regulation of Phosphorylation of PTK2 1 0.39 0.17 0.46
8 INT116928 PTK2 Positive_regulation of JUN 1 0.20 0.15 0.46
9 INT117776 Binding of Ptk2 and Regulation of Phosphorylation of Ddr1 1 0.10 0.17 0.46
10 INT295360 Ntn1 Positive_regulation of Ptk2 1 0.09 0.51 0.29
11 INT162599 Wnt5a Regulation of Gene_expression of IL4I1 1 0.00 0.1 0.28
12 INT283858 Binding of PTK2 and APOA5 1 0.00 0.67 0.21
13 INT178086 Binding of EDNRA and PTK2 1 0.07 0.82 0.2
14 INT178092 EDN3 Positive_regulation of PTK2 1 0.01 1.02 0.17
15 INT178073 EDN1 Positive_regulation of PTK2 1 0.03 1.02 0.17
16 INT147727 Phosphorylation of PTK2 Regulation of Positive_regulation of RAC1 1 0.34 0.32 0.14
17 INT147726 Phosphorylation of PTK2 Regulation of Positive_regulation of PIK3CA 1 0.09 0.32 0.14
18 INT287884 WNT5A Positive_regulation of THEMIS 1 0.00 0.08 0.13
19 INT327405 Lox Positive_regulation of Ptk2 1 0.42 1.3 0.1
20 INT233510 Wnt5a Positive_regulation of Gene_expression of Il12a 1 0.03 0.33 0.1
21 INT178089 Binding of EDNRA and Positive_regulation of PTK2 1 0.09 0.74 0.09
22 INT211960 Wnt5a Positive_regulation of Car2 1 0.13 0.38 0.08
23 INT287879 Binding of WNT5A and FZD5 1 0.06 1.16 0.08
24 INT355582 VEGFA Regulation of Positive_regulation of PTK2 1 0.05 1.46 0.08
25 INT329265 Binding of Ptk2 and Wnt2 1 0.05 1.04 0.07
26 INT333260 Gene_expression of Cxcl12 Negative_regulation of Gene_expression of Ptk2 1 0.21 1 0.07
27 INT333257 Gene_expression of Cxcl12 Negative_regulation of Ptk2 1 0.21 1 0.07
28 INT346280 Binding of COL5A2 and PTK2 1 0.01 0.1 0.05
29 INT269249 Ptk2 Positive_regulation of Phosphorylation of Src 1 0.13 0.93 0.04
30 INT269250 Ptk2 Positive_regulation of Src 1 0.13 0.86 0.04
31 INT271526 Binding of ESB3 and Ptk2 1 0.01 0.97 0.03
32 INT351680 Fut1 Regulation of Ptk2 1 0.01 1.68 0
33 INT292464 Binding of PTK2 and MMRN1 1 0.03 0.26 0
34 INT292505 PTK2 Regulation of Birc5 1 0.29 0.76 0
35 INT292444 BAD Positive_regulation of Phosphorylation of PTK2 1 0.13 0.9 0
36 INT292463 LAMB2 Positive_regulation of Phosphorylation of PTK2 1 0.01 0.7 0
37 INT335884 Akt1 Regulation of Positive_regulation of Wnt5a 1 0.03 0.15 0
38 INT292497 Mlph Positive_regulation of Phosphorylation of PTK2 1 0.05 7.24 0
39 INT269248 Lox Negative_regulation of Ptk2 1 0.24 1.02 0
40 INT292498 Mlph Regulation of Phosphorylation of PTK2 1 0.02 0.33 0
41 INT292452 Gene_expression of PTK2 Negative_regulation of Positive_regulation of AKT1 1 0.14 0.6 0
42 INT292453 PTK2 Regulation of Gene_expression of GEM 1 0.16 0.42 0
43 INT283863 Binding of MAPK1 and PTK2 1 0.12 0.97 0
44 INT295409 Ptk2 Positive_regulation of Phosphorylation of Oprk1 1 0.01 0 0
45 INT335883 Binding of Lrp6 and Wnt5a 1 0.27 0.08 0
46 INT292495 Mlph Regulation of Gene_expression of PTK2 1 0.03 0.21 0
47 INT292461 PTK2 Regulation of BCL2 1 0.02 0.76 0
48 INT292451 PTK2 Regulation of BAX 1 0.02 0.76 0
49 INT292448 Positive_regulation of PTK2 Positive_regulation of Phosphorylation of AKT1 1 0.15 0.28 0
50 INT295402 Ptk2 Positive_regulation of Localization of Oprk1 1 0.01 0 0
51 INT292457 PTK2 Regulation of BAD 1 0.03 0.76 0
52 INT351676 Fut1 Negative_regulation of Ptk2 1 0.01 4.39 0
53 INT292506 Mlph Regulation of PTK2 1 0.01 0.21 0
54 INT351677 Fut1 Negative_regulation of Gene_expression of Ptk2 1 0.01 3.64 0
55 INT292460 GEM Positive_regulation of Phosphorylation of PTK2 1 0.20 0.52 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of synapse assembly. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of synapse assembly. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT83597 Phosphorylation of Ptk2 20 0.82 3.24 5.7
2 INT87345 Phosphorylation of PTK2 110 0.82 59.39 4.28
3 INT117773 Positive_regulation of Phosphorylation of Ptk2 9 0.69 0.89 3.71
4 INT83596 Gene_expression of Ptk2 6 0.76 2.22 1.84
5 INT116110 Positive_regulation of PTK2 20 0.66 10.53 1.64
6 INT206471 Positive_regulation of Ptk2 34 0.51 25.75 1.61
7 INT111946 Positive_regulation of Phosphorylation of PTK2 8 0.66 11.5 1.53
8 INT131115 Regulation of Phosphorylation of Ptk2 2 0.61 0.3 1.34
9 INT87343 Negative_regulation of Phosphorylation of PTK2 34 0.59 18.38 1.19
10 INT87346 Binding of PTK2 6 0.37 4.03 1.18
11 INT150074 Gene_expression of WNT5A 8 0.75 6.3 1.17
12 INT87342 Regulation of Phosphorylation of PTK2 3 0.59 5.7 1.05
13 INT87344 Gene_expression of PTK2 90 0.78 59.03 0.87
14 INT131113 Negative_regulation of Ptk2 3 0.58 0.17 0.85
15 INT134207 Gene_expression of Ptk2 56 0.73 31.97 0.78
16 INT87341 Regulation of Gene_expression of PTK2 2 0.62 8.34 0.77
17 INT150075 Positive_regulation of Gene_expression of WNT5A 2 0.67 2.53 0.59
18 INT134208 Negative_regulation of Ptk2 19 0.58 23.59 0.52
19 INT117772 Binding of Ptk2 1 0.37 0.17 0.46
20 INT271521 Phosphorylation of Ptk2 10 0.59 11.45 0.39
21 INT83594 Negative_regulation of Phosphorylation of Ptk2 5 0.42 1.62 0.29
22 INT271522 Negative_regulation of Phosphorylation of Ptk2 3 0.19 2.09 0.26
23 INT119080 Negative_regulation of PTK2 15 0.56 8.88 0.23
24 INT87338 Regulation of PTK2 10 0.62 4.75 0.21
25 INT308522 Positive_regulation of Positive_regulation of Ptk2 2 0.22 2.37 0.21
26 INT292483 Negative_regulation of Positive_regulation of PTK2 2 0.41 3.51 0.18
27 INT283561 Regulation of Gene_expression of Ptk2 5 0.42 1.1 0.17
28 INT147730 Regulation of Positive_regulation of PTK2 1 0.35 0.33 0.15
29 INT83595 Negative_regulation of Gene_expression of Ptk2 1 0.23 1.62 0.14
30 INT131114 Positive_regulation of Gene_expression of Ptk2 1 0.49 0.27 0.14
31 INT327399 Negative_regulation of Positive_regulation of Ptk2 7 0.43 4.75 0.13
32 INT269240 Regulation of Ptk2 6 0.42 2.84 0.13
33 INT283567 Regulation of Regulation of Ptk2 1 0.42 0.3 0.13
34 INT162574 Gene_expression of Wnt5a 7 0.47 0.92 0.1
35 INT282594 Localization of WNT5A 2 0.18 0.89 0.1
36 INT233483 Regulation of Gene_expression of Wnt5a 1 0.19 0.33 0.1
37 INT283560 Negative_regulation of Gene_expression of Ptk2 6 0.40 4.84 0.09
38 INT271523 Positive_regulation of Gene_expression of Ptk2 6 0.65 8 0.08
39 INT162576 Positive_regulation of Wnt5a 3 0.48 0.71 0.08
40 INT147735 Regulation of Binding of PTK2 1 0.35 0.23 0.08
41 INT290078 Regulation of WNT5A 1 0.07 2.3 0.07
42 INT144400 Positive_regulation of Gene_expression of PTK2 33 0.70 21.24 0.06
43 INT333217 Regulation of Positive_regulation of Ptk2 1 0.12 0.36 0.05
44 INT329775 Regulation of Regulation of PTK2 1 0.11 0.49 0.05
45 INT238180 Binding of Ptk2 5 0.35 2.99 0.04
46 INT327396 Positive_regulation of Negative_regulation of Ptk2 1 0.37 0.95 0.04
47 INT295374 Positive_regulation of Ptk2 1 0.34 0.06 0.04
48 INT292474 Negative_regulation of Gene_expression of PTK2 8 0.41 5.17 0
49 INT283566 Localization of Ptk2 5 0.75 0.93 0
50 INT262779 Localization of PTK2 3 0.71 2.75 0
51 INT292478 Negative_regulation of Negative_regulation of PTK2 1 0.41 0.97 0
52 INT283564 Positive_regulation of Localization of Ptk2 1 0.47 0 0
53 INT329769 Positive_regulation of Localization of PTK2 1 0.17 1.42 0
54 INT295392 Positive_regulation of Localization of Ptk2 1 0.37 0 0
55 INT335880 Regulation of Wnt5a 1 0.32 0.07 0
56 INT351669 Negative_regulation of Binding of Ptk2 1 0.40 0.73 0
57 INT295387 Localization of Ptk2 1 0.55 0 0
58 INT206472 Transcription of Ptk2 1 0.52 0.46 0
59 INT238159 Regulation of Binding of Ptk2 1 0.03 0.06 0
60 INT292481 Negative_regulation of Localization of PTK2 1 0.41 0.07 0
61 INT162572 Positive_regulation of Gene_expression of Wnt5a 1 0.02 0.3 0
62 INT329766 Positive_regulation of Positive_regulation of PTK2 1 0.11 0.51 0
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