GO:0051966

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Name regulation of synaptic transmission, glutamatergic
Categary Process
Go Slim No
Go Link GO:0051966
Unique Molecular Interactions 424
Total Molecular Interactions 551
Total Single Events 4987
Pain Genes Associated 16

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of synaptic transmission, glutamatergic. They are ordered first by their pain relevance and then by number of times they were reported for regulation of synaptic transmission, glutamatergic. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT296484 Binding of Gria2 and GRIP1 1 0.04 4.52 4.59
2 INT143270 Binding of Cnr1 and Gprasp1 4 0.54 0.64 4.18
3 INT127128 Binding of CNR1 and CNR2 8 0.39 3.98 3.97
4 INT136514 Binding of Grm1 and Grm5 4 0.12 1.8 3.9
5 INT130625 Prkcg Regulation of Prkaca 1 0.23 1.32 3.87
6 INT264929 Binding of Cnr1 and Gnaz 1 0.18 1.71 2.89
7 INT298456 Prkaca Positive_regulation of Phosphorylation of Adarb1 1 0.00 1.86 2.85
8 INT351444 Grin1 Positive_regulation of Gria2 1 0.22 1.5 2.64
9 INT104219 SCD Positive_regulation of Cnr1 1 0.00 2.67 2.54
10 INT143271 Binding of Gprasp1 and Positive_regulation of Negative_regulation of Cnr1 1 0.78 0.16 2.53
11 INT143272 Binding of CNR1 and Gprasp1 1 0.01 0.17 2.42
12 INT121746 Prkaca Positive_regulation of Ephb1 2 0.23 0.92 2.35
13 INT238914 Positive_regulation of CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 3.22 2.35
14 INT198958 Cnr1 Positive_regulation of Kcnj9 1 0.00 0.15 2.24
15 INT281084 Prkaca Positive_regulation of Mapk1 2 0.25 0 2.06
16 INT104855 Prkaca Regulation of TRPV1 3 0.06 1.52 1.92
17 INT264928 Binding of Cnr1 and Hrh1 1 0.01 1.61 1.92
18 INT112514 Binding of Prkaca and Trib3 1 0.03 1.18 1.9
19 INT186432 Prkaca Regulation of Creb1 1 0.14 0.45 1.9
20 INT112517 Binding of Ephb1 and Prkaca 3 0.18 0.58 1.85
21 INT332773 Positive_regulation of Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.04 0.73 1.75
22 INT139156 Binding of Gria1 and Gria2 1 0.23 0.64 1.72
23 INT264922 Binding of Cnr1 and Mors1 1 0.14 0.1 1.71
24 INT139433 Binding of Prkaca and Prkca 1 0.37 0.13 1.67
25 INT122286 Prkaca Negative_regulation of Negative_regulation of Calca 1 0.12 0.54 1.63
26 INT195930 OPRM1 Regulation of Prkaca 1 0.01 0 1.59
27 INT111076 Psen1 Regulation of Psenen 1 0.17 0.76 1.58
28 INT192081 Igkv11-125 Positive_regulation of Cnr1 1 0.10 0.23 1.51
29 INT121741 Prkaca Negative_regulation of Positive_regulation of Creb1 1 0.10 0.2 1.49
30 INT150069 Cnr1 Regulation of Cnr2 2 0.50 0.83 1.42
31 INT78974 Binding of Prkcg and Prkaca 2 0.31 0.35 1.4
32 INT262568 Prkaca Regulation of Trpv1 2 0.10 0.65 1.38
33 INT355252 Binding of Cacna1a and Cnr1 1 0.04 0 1.31
34 INT198957 Binding of Cnr1 and Mastl 1 0.00 0 1.31
35 INT192080 Foxm1 Positive_regulation of Cnr1 2 0.14 0.72 1.3
36 INT124926 Negative_regulation of Prkaca Negative_regulation of Localization of Pag1 1 0.00 0.61 1.3
37 INT169289 CNR1 Positive_regulation of EGFR 1 0.62 0.36 1.28
38 INT195929 Binding of OPRM1 and Prkaca 1 0.02 0.33 1.27
39 INT141244 Fos Regulation of Prkaca 1 0.18 0.07 1.24
40 INT195926 Prkaca Positive_regulation of Trpv1 1 0.10 0.44 1.24
41 INT75229 Prkaca Positive_regulation of Phosphorylation of Oprm1 1 0.44 0 1.22
42 INT76163 Prkaca Positive_regulation of Phosphorylation of Oprm1 1 0.02 0.08 1.22
43 INT210982 Binding of Cnr1 and Cfp 2 0.22 1.27 1.2
44 INT63384 Binding of Cnr1 and Insrr 1 0.03 0.24 1.2
45 INT281077 Binding of Gria2 and Gria3 2 0.24 0.35 1.19
46 INT141245 Prkaca Regulation of Gene_expression of Th 1 0.15 0.17 1.17
47 INT85780 Prkaca Regulation of Prkcg 1 0.29 0.47 1.17
48 INT238916 CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 1.61 1.17
49 INT212815 WAS Positive_regulation of CNR1 1 0.01 0.62 1.16
50 INT212824 WAS Positive_regulation of Cnr1 1 0.21 0.62 1.16
51 INT264930 Gnaz Positive_regulation of Negative_regulation of Cnr1 1 0.20 0 1.14
52 INT225104 CNR1 Positive_regulation of Gene_expression of RETNLB 1 0.01 1.41 1.14
53 INT123387 Binding of Camk2a and Gria2 1 0.13 0.32 1.14
54 INT110671 Binding of Cnr1 and Alox5 1 0.07 0.2 1.13
55 INT130627 Gnas Regulation of Prkaca 1 0.00 0 1.13
56 INT123454 CNR1 Regulation of Fos 1 0.00 0.06 1.12
57 INT123455 CNR1 Regulation of Positive_regulation of Fos 1 0.00 0.06 1.12
58 INT269200 Prkaca Positive_regulation of Phosphorylation of Ceacam3 1 0.03 0.65 1.09
59 INT352468 Calca Positive_regulation of Prkaca 1 0.11 0.8 1.08
60 INT96906 Plxna3 Regulation of Regulation of Prkaca 1 0.17 0.71 1.08
61 INT296458 Binding of Gria2 and Pick1 3 0.24 1.86 1.07
62 INT296460 Binding of Gria2 and Myo18a 1 0.01 1.49 1.06
63 INT269198 Prkaca Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
64 INT269199 Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.03 0.56 1.05
65 INT240453 Prkcg Positive_regulation of Positive_regulation of Prkaca 1 0.23 0.63 1.01
66 INT240455 Ephb1 Positive_regulation of Positive_regulation of Prkaca 1 0.22 0.63 1.01
67 INT186161 Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.11 1.05 1.01
68 INT320021 Prkaca Regulation of Positive_regulation of Kcnma1 1 0.00 0.54 1
69 INT351443 Cnr1 Regulation of Positive_regulation of Vta1 1 0.12 0.93 0.99
70 INT276864 Positive_regulation of Gpr65 Positive_regulation of Prkaca 1 0.16 0.74 0.97
71 INT281085 Binding of Gria2 and Nsf 2 0.26 0.4 0.94
72 INT264932 D2Mit212 Positive_regulation of Binding of Cnr1 1 0.06 0.2 0.94
73 INT252877 Prkaca Positive_regulation of Regulation of Grip2 1 0.01 0.22 0.94
74 INT252878 Prkaca Regulation of Regulation of Grip2 1 0.01 0.22 0.94
75 INT120380 Cnr1 Positive_regulation of Gene_expression of Fos 1 0.31 0.45 0.93
76 INT111078 Binding of Cnr1 and Cnr2 2 0.05 0 0.92
77 INT252880 Positive_regulation of Prkaca Positive_regulation of Gene_expression of Tacr1 1 0.02 0.29 0.92
78 INT195927 Binding of Prkaca and Trpv1 1 0.07 0.28 0.92
79 INT281082 Binding of Gria2 and Ltp 1 0.24 0.6 0.9
80 INT252876 Positive_regulation of Prkaca Regulation of Gene_expression of Tacr1 1 0.01 0.28 0.89
81 INT196834 Prkaca Positive_regulation of Phosphorylation of Ppp1r1b 2 0.15 0 0.87
82 INT112914 Ppp1r1b Negative_regulation of Prkaca 3 0.22 0.13 0.86
83 INT264925 D2Mit212 Negative_regulation of Cnr1 1 0.05 0 0.84
84 INT122191 Binding of Crh and Ucn 4 0.36 0.79 0.82
85 INT185937 NOS2 Regulation of Prkaca 1 0.03 1.08 0.82
86 INT78972 Prkaca Regulation of Ina 1 0.11 0.09 0.82
87 INT40610 Binding of Prkaca and Oprl1 1 0.02 0.09 0.8
88 INT72418 Binding of Cnr1 and Cnr2 3 0.42 0.07 0.79
89 INT186439 Prkaca Regulation of Phosphorylation of Creb1 1 0.06 0.08 0.79
90 INT240454 Ephb1 Regulation of Prkaca 1 0.14 0.51 0.79
91 INT111361 Cnr1 Negative_regulation of Localization of Calca 1 0.01 0 0.78
92 INT91239 Prkaca Regulation of Negative_regulation of Oprm1 1 0.43 0 0.76
93 INT164996 Ins1 Regulation of Gria2 1 0.05 0.05 0.76
94 INT226122 Ghrl Regulation of Cnr1 1 0.25 0.09 0.76
95 INT69692 Helt Regulation of Prkaca 1 0.00 0.33 0.76
96 INT292598 CNR1 Regulation of ABAT 1 0.08 0.32 0.75
97 INT166414 Gprasp1 Regulation of Negative_regulation of Cnr1 1 0.37 0.3 0.75
98 INT81011 CNR1 Positive_regulation of Gene_expression of PENK 1 0.54 0 0.75
99 INT292599 CNR1 Regulation of Localization of ABAT 1 0.08 0.32 0.75
100 INT262578 Prkaca Positive_regulation of Localization of Calca 1 0.03 0.71 0.75
101 INT127584 Binding of CNR1 and Ctbp1 1 0.00 0.6 0.75
102 INT144455 Binding of CNR1 and GPM6A 1 0.02 0 0.74
103 INT196799 Prkaca Positive_regulation of Phosphorylation of Trh 1 0.02 0 0.74
104 INT244025 Prkaca Regulation of Phosphorylation of Gabrg1 1 0.08 0.18 0.72
105 INT351350 Prkaca Regulation of Lpar1 1 0.04 0.58 0.72
106 INT102123 Ngf Regulation of Gene_expression of Cnr1 1 0.53 0.42 0.71
107 INT148449 Gene_expression of Inhbe Positive_regulation of Prkaca 1 0.05 0.68 0.71
108 INT102121 Gdnf Regulation of Gene_expression of Cnr1 1 0.45 0.42 0.71
109 INT161297 Ppp1r1b Negative_regulation of Prkaca 1 0.10 0.16 0.7
110 INT186162 Phosphorylation of Prkaca Positive_regulation of Phosphorylation of Prkcg 1 0.04 0.22 0.7
111 INT282139 Grm1 Regulation of Grip2 1 0.00 0.62 0.69
112 INT150067 Cnr1 Regulation of Gene_expression of Oprd1 1 0.01 0.23 0.69
113 INT307046 Tmie Positive_regulation of Cnr1 1 0.05 0.31 0.69
114 INT120381 Binding of CNR1 and Fos 1 0.00 0.52 0.68
115 INT210983 Calb1 Positive_regulation of Cnr1 1 0.01 0.81 0.68
116 INT122190 Binding of Crhr1 and Ucn 4 0.49 0.65 0.67
117 INT264927 Cnr1 Regulation of Gnaz 1 0.23 0.05 0.66
118 INT162223 Grin1 Positive_regulation of Localization of Gria2 1 0.23 0.07 0.66
119 INT213895 Mastl Regulation of Gene_expression of Cnr1 1 0.17 0.26 0.66
120 INT128978 Cnr1 Positive_regulation of Cnr2 1 0.56 0.96 0.65
121 INT150754 GTS Negative_regulation of Gene_expression of Prkaca 1 0.32 0.08 0.65
122 INT235881 Prkaca Positive_regulation of Creb1 2 0.10 0.16 0.64
123 INT104858 Prkaca Negative_regulation of Negative_regulation of TRPV1 2 0.10 0.41 0.64
124 INT112513 Binding of Prkaca and Prkce 1 0.04 0.4 0.64
125 INT102863 Prkaca Regulation of Srgn 1 0.50 0.05 0.64
126 INT110342 Binding of CNR1 and TRPV1 1 0.33 0 0.63
127 INT281081 Prkaca Positive_regulation of Gene_expression of Adcy1 1 0.12 0 0.63
128 INT324065 Ptger2 Positive_regulation of Prkaca 2 0.24 0.63 0.61
129 INT281086 Prkaca Positive_regulation of Mdk 1 0.08 0 0.61
130 INT111839 Binding of Cnr1 and Cnr2 1 0.05 0.53 0.6
131 INT169299 CNR1 Positive_regulation of Localization of IL8 1 0.20 0.11 0.59
132 INT169291 CNR1 Positive_regulation of Gene_expression of PTPLA 1 0.19 0.11 0.59
133 INT169292 Positive_regulation of CNR1 Positive_regulation of Gene_expression of PTPLA 1 0.19 0.11 0.59
134 INT244055 Prkaca Regulation of Gabrg1 1 0.08 0 0.58
135 INT102864 Prkaca Regulation of Twist1 1 0.48 0.05 0.58
136 INT169290 CNR1 Positive_regulation of Negative_regulation of TXK 1 0.10 0.18 0.58
137 INT169286 CNR1 Positive_regulation of Phosphorylation of EGFR 1 0.45 0.18 0.57
138 INT356320 ORF61 Positive_regulation of Positive_regulation of Prkaca 1 0.01 0.05 0.57
139 INT296472 Camk2a Positive_regulation of Prkaca 1 0.09 0.32 0.57
140 INT282142 Grm1 Positive_regulation of Positive_regulation of Trib3 1 0.01 0.27 0.57
141 INT296446 Binding of Gria2 and Gria4 1 0.13 0.55 0.57
142 INT98815 Binding of Crhr2 and Ucn 3 0.32 0.5 0.56
143 INT203033 Cnr1 Regulation of Cnr2 1 0.15 0.29 0.56
144 INT261485 Positive_regulation of Prkaca Positive_regulation of Phosphorylation of Ephb1 1 0.05 0.12 0.56
145 INT103184 Prkaca Positive_regulation of Phosphorylation of CRTC1 1 0.01 0.57 0.55
146 INT296293 Prkaca Regulation of Positive_regulation of Creb1 1 0.16 0.62 0.55
147 INT343597 Gys1 Regulation of Transcription of Gria2 1 0.00 0 0.55
148 INT296291 Prkaca Regulation of Localization of Calm3 1 0.09 0.62 0.55
149 INT296273 Prkaca Regulation of Localization of Camk4 1 0.16 0.62 0.55
150 INT296462 Prkca Positive_regulation of Phosphorylation of Gria2 1 0.15 0.3 0.55
151 INT311179 CNR1 Negative_regulation of Transcription of CNR2 1 0.41 2.05 0.55
152 INT259184 Binding of Gria2 and Gria1 2 0.26 0.28 0.54
153 INT141072 GPRASP1 Positive_regulation of Negative_regulation of CNR1 1 0.56 0.09 0.54
154 INT89059 Positive_regulation of Prkaca Positive_regulation of Gene_expression of Trpv1 1 0.07 0.16 0.54
155 INT155359 CNR2 Negative_regulation of CNR1 1 0.46 0.5 0.54
156 INT296485 Negative_regulation of Binding of Gria2 and GRIP1 1 0.05 0.3 0.54
157 INT156517 Binding of CNR1 and FAAH 3 0.38 1.53 0.53
158 INT291386 Cntf Regulation of Gene_expression of Gria2 1 0.11 0.13 0.53
159 INT111840 Binding of Cnr1 and sar 1 0.04 0.45 0.52
160 INT87559 Vip Positive_regulation of Prkaca 1 0.28 0 0.52
161 INT87557 Crh Positive_regulation of Prkaca 1 0.27 0 0.52
162 INT196830 Arpp21 Regulation of Prkaca 1 0.01 0 0.52
163 INT303720 Prkaca Regulation of Bdkrb1 1 0.02 0.33 0.52
164 INT89058 Prkaca Regulation of Phosphorylation of Trpv1 1 0.04 0.35 0.51
165 INT196824 Ppp1r1b Regulation of Prkaca 1 0.10 0 0.51
166 INT342689 Ptger4 Positive_regulation of Prkaca 1 0.03 0.24 0.51
167 INT87558 Calca Positive_regulation of Prkaca 1 0.35 0 0.51
168 INT262565 Prkaca Regulation of Negative_regulation of Trpv1 1 0.05 0.21 0.5
169 INT313376 Cnr1 Positive_regulation of Phosphorylation of Mapk14 1 0.20 0.38 0.5
170 INT313371 Cnr1 Positive_regulation of Gene_expression of Gfap 1 0.35 0.39 0.5
171 INT243998 Binding of Prkaca and Dnm1 1 0.11 0.24 0.49
172 INT244037 Positive_regulation of Binding of Prkaca and Tfap2a 1 0.01 0.24 0.49
173 INT244021 Positive_regulation of Binding of Cacnb3 and Prkaca 1 0.02 0.24 0.49
174 INT243999 Positive_regulation of Binding of Prkaca and Dnm1 1 0.14 0.24 0.49
175 INT244036 Binding of Cacnb3 and Prkaca 1 0.01 0.24 0.49
176 INT244035 Binding of Prkaca and Tfap2a 1 0.01 0.24 0.49
177 INT259183 Gria1 Positive_regulation of Phosphorylation of Gria2 1 0.30 0.39 0.49
178 INT77377 Binding of Cnr1 and Fbln5 1 0.02 0 0.48
179 INT268473 Negative_regulation of CNR1 Negative_regulation of Cysltr1 1 0.00 1.02 0.48
180 INT342693 Binding of Prkaca and Gopc 1 0.01 0.23 0.48
181 INT141729 NR3C1 Regulation of Positive_regulation of Cnr1 1 0.06 0.7 0.47
182 INT168110 Binding of Cnr1 and Dbh 1 0.04 0.64 0.47
183 INT101325 Binding of Cnr1 and Trpv1 1 0.32 0 0.47
184 INT351446 Gria2 Negative_regulation of Casp3 1 0.02 0.37 0.47
185 INT168111 Dbh Positive_regulation of Cnr1 1 0.05 0.64 0.47
186 INT101327 Binding of Cnr1 and Amt 1 0.25 0 0.47
187 INT307048 Cnr1 Positive_regulation of Casp3 1 0.08 0 0.47
188 INT123714 Binding of Cnr1 and oh 1 0.01 0.3 0.47
189 INT296451 Prkaca Regulation of Phosphorylation of Rbm39 1 0.00 0.27 0.47
190 INT226125 Ghrl Positive_regulation of Cnr1 1 0.44 0.06 0.46
191 INT235404 Positive_regulation of RTCA Positive_regulation of Positive_regulation of Prkaca 1 0.00 0.22 0.45
192 INT153994 Regulation of Prkaca Regulation of TRPV1 1 0.02 0.46 0.44
193 INT78975 Positive_regulation of Prkaca Regulation of Ina 1 0.09 0 0.43
194 INT102862 Prkaca Regulation of Phosphorylation of Twist1 1 0.19 0.1 0.42
195 INT139488 Oprm1 Positive_regulation of Cnr1 1 0.17 0.1 0.42
196 INT196821 Phosphorylation of Ppp1r1b Positive_regulation of Prkaca 1 0.09 0 0.41
197 INT261652 Binding of MAPK1 and PSEN1 1 0.22 1.25 0.41
198 INT78971 Positive_regulation of Prkaca Positive_regulation of Ina 1 0.09 0.09 0.41
199 INT196797 Trh Negative_regulation of Prkaca 1 0.01 0 0.41
200 INT97789 Positive_regulation of Cnr1 Negative_regulation of Gene_expression of Nos2 1 0.12 0.23 0.4

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of synaptic transmission, glutamatergic. They are ordered first by their pain relevance and then by number of times they were reported in regulation of synaptic transmission, glutamatergic. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT65731 Gene_expression of Cnr1 234 0.78 63.82 109.34
2 INT52651 Positive_regulation of Prkaca 136 0.67 40.82 99.16
3 INT69764 Positive_regulation of Cnr1 126 0.70 67.8 91.49
4 INT74376 Gene_expression of Cnr1 173 0.78 73.43 89.7
5 INT15898 Positive_regulation of Prkaca 199 0.70 50.89 87.54
6 INT49111 Negative_regulation of Prkaca 102 0.59 27.44 71.77
7 INT53964 Negative_regulation of Prkaca 131 0.58 38.76 69.52
8 INT65733 Positive_regulation of Cnr1 125 0.70 40.27 67.33
9 INT6894 Gene_expression of CNR1 168 0.78 74.07 62.84
10 INT50334 Negative_regulation of Cnr1 84 0.58 30.86 51.75
11 INT62630 Positive_regulation of CNR1 86 0.70 40.34 51.51
12 INT63383 Binding of Cnr1 77 0.48 22.28 44.61
13 INT66383 Phosphorylation of Prkaca 143 0.80 30.85 43.38
14 INT16194 Binding of CNR1 82 0.48 20.75 39.59
15 INT12608 Regulation of CNR1 62 0.60 24.36 36.02
16 INT66005 Regulation of Cnr1 47 0.61 19.21 34.52
17 INT50308 Binding of Cnr1 61 0.48 14.41 33.52
18 INT89055 Phosphorylation of Prkaca 60 0.61 13.41 32.49
19 INT64918 Gene_expression of Gria2 108 0.74 29.95 29.67
20 INT56525 Gene_expression of Gria2 74 0.75 23.15 28.6
21 INT66381 Regulation of Prkaca 40 0.62 13.38 27.96
22 INT111359 Localization of Cnr1 55 0.81 11.25 27.41
23 INT75418 Negative_regulation of Cnr1 41 0.59 14.65 27.28
24 INT74377 Regulation of Cnr1 38 0.59 16.93 24.77
25 INT96904 Regulation of Prkaca 33 0.44 10.86 24.51
26 INT101225 Positive_regulation of Gria2 62 0.64 28.1 23.93
27 INT89805 Gene_expression of Prkaca 45 0.77 11.03 20.77
28 INT10442 Negative_regulation of CNR1 47 0.59 20.88 20.2
29 INT79955 Localization of Cnr1 26 0.81 8.44 19.06
30 INT95930 Negative_regulation of Gria2 63 0.56 18.37 17.04
31 INT48055 Gene_expression of Grm1 27 0.78 14.29 17.01
32 INT87932 Positive_regulation of Gene_expression of Cnr1 28 0.69 8.86 16.38
33 INT62629 Localization of CNR1 35 0.76 11.86 16.3
34 INT62861 Regulation of Gria2 45 0.60 13.35 16.07
35 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83
36 INT143276 Phosphorylation of Gria2 42 0.80 16.07 15.2
37 INT114510 Positive_regulation of Gria2 36 0.57 14.91 14.85
38 INT77619 Gene_expression of Prkaca 43 0.75 8.55 14.13
39 INT74375 Positive_regulation of Gene_expression of Cnr1 24 0.70 14.25 13.66
40 INT69763 Positive_regulation of Positive_regulation of Cnr1 12 0.50 9.05 12.46
41 INT100919 Positive_regulation of Grm1 21 0.70 7.82 11.55
42 INT78970 Positive_regulation of Positive_regulation of Prkaca 14 0.47 3.06 11.49
43 INT259165 Phosphorylation of Gria2 4 0.65 11.65 11.07
44 INT57069 Regulation of Gria2 28 0.44 10.11 11.06
45 INT102370 Positive_regulation of Grm2 10 0.45 5.03 10.9
46 INT106565 Negative_regulation of Gene_expression of Cnr1 19 0.59 6.98 9.93
47 INT115614 Binding of Gria2 25 0.43 8.97 9.91
48 INT82769 Positive_regulation of Grm1 20 0.00 7.78 9.82
49 INT66382 Positive_regulation of Phosphorylation of Prkaca 33 0.49 7.05 9.69
50 INT259169 Positive_regulation of Phosphorylation of Gria2 3 0.40 9.98 9.34
51 INT40609 Binding of Prkaca 23 0.36 3.42 9.19
52 INT71478 Positive_regulation of Positive_regulation of Prkaca 21 0.37 5.14 8.85
53 INT91772 Gene_expression of PSEN1 115 0.75 38.12 8.48
54 INT78766 Negative_regulation of Gria2 20 0.52 6.27 8.12
55 INT142526 Positive_regulation of Gene_expression of Prkaca 12 0.46 2.48 8.05
56 INT10444 Positive_regulation of Gene_expression of CNR1 18 0.69 8.69 7.84
57 INT87976 Regulation of Gene_expression of Cnr1 9 0.58 6.87 7.51
58 INT114509 Transcription of Gria2 10 0.58 0.75 7.27
59 INT86898 Negative_regulation of Gene_expression of Cnr1 13 0.55 3.33 7.25
60 INT96969 Positive_regulation of Positive_regulation of CNR1 9 0.48 1.27 7.19
61 INT89052 Positive_regulation of Phosphorylation of Prkaca 13 0.37 2.92 7.05
62 INT68466 Negative_regulation of Positive_regulation of Prkaca 6 0.57 2.29 6.83
63 INT94649 Gene_expression of Grm1 19 0.77 5.11 6.58
64 INT10445 Transcription of CNR1 16 0.68 6.75 6.4
65 INT111069 Regulation of Psen1 19 0.44 7.78 5.87
66 INT85777 Regulation of Negative_regulation of Prkaca 7 0.46 1.85 5.76
67 INT85404 Transcription of Cnr1 12 0.72 3.15 5.73
68 INT71477 Negative_regulation of Positive_regulation of Prkaca 10 0.37 1.69 5.57
69 INT112102 Regulation of Gene_expression of Gria2 14 0.55 5.4 5.55
70 INT57068 Regulation of Gene_expression of Gria2 12 0.36 3.76 5.44
71 INT113153 Regulation of Grm1 6 0.44 4.11 5.41
72 INT90961 Negative_regulation of Positive_regulation of Cnr1 7 0.42 0.6 5.24
73 INT135998 Localization of Gria2 18 0.72 3.14 5.15
74 INT259167 Negative_regulation of Phosphorylation of Gria2 2 0.34 5.24 5.13
75 INT85946 Localization of Gria2 10 0.61 1.23 5.09
76 INT26042 Binding of Gria2 20 0.40 4.88 5.04
77 INT90962 Regulation of Positive_regulation of Cnr1 6 0.61 1.25 4.99
78 INT71244 Binding of Prkaca 8 0.30 2.64 4.96
79 INT100920 Positive_regulation of Gene_expression of Grm1 7 0.70 5.88 4.87
80 INT91055 Negative_regulation of Grm1 7 0.45 5.14 4.87
81 INT114511 Positive_regulation of Gene_expression of Gria2 14 0.41 3.9 4.71
82 INT111358 Regulation of Localization of Cnr1 3 0.39 0.09 4.53
83 INT100520 Regulation of Grm1 8 0.44 1.3 4.48
84 INT74373 Phosphorylation of Cnr1 3 0.79 1.88 4.45
85 INT108354 Negative_regulation of Phosphorylation of Prkaca 18 0.41 6.24 4.37
86 INT111067 Positive_regulation of Gene_expression of Psen1 32 0.68 21.2 4.19
87 INT74814 Binding of Grm1 5 0.45 2.69 4.1
88 INT90983 Regulation of Gene_expression of Cnr1 8 0.45 2.59 4.03
89 INT87974 Transcription of Cnr1 15 0.65 2.51 4.02
90 INT113204 Negative_regulation of Positive_regulation of Cnr1 6 0.40 4.89 4.02
91 INT120742 Negative_regulation of Gene_expression of Prkaca 6 0.24 3.76 3.86
92 INT95556 Negative_regulation of Binding of Cnr1 5 0.58 3.1 3.67
93 INT84005 Negative_regulation of Positive_regulation of CNR1 7 0.41 3.55 3.66
94 INT80923 Negative_regulation of Binding of CNR1 7 0.19 0.78 3.61
95 INT116623 Localization of Prkaca 15 0.73 2.89 3.59
96 INT95785 Positive_regulation of Positive_regulation of Grm1 6 0.49 3.59 3.3
97 INT78969 Regulation of Positive_regulation of Prkaca 5 0.37 1.38 3.29
98 INT170351 Positive_regulation of Gene_expression of Gria2 13 0.67 3.67 3.27
99 INT211591 Negative_regulation of PSEN1 14 0.57 5.73 3.26
100 INT10443 Regulation of Gene_expression of CNR1 10 0.50 3.96 3.06
101 INT106283 Regulation of Positive_regulation of Cnr1 3 0.37 2.61 3.05
102 INT193936 Positive_regulation of PSEN1 5 0.58 11.57 2.95
103 INT69099 Gene_expression of Serpine2 22 0.78 7.89 2.87
104 INT111422 Positive_regulation of Regulation of CNR1 3 0.03 0.56 2.76
105 INT143189 Positive_regulation of Binding of Cnr1 3 0.35 0.37 2.74
106 INT90982 Regulation of Transcription of Cnr1 3 0.26 1.37 2.7
107 INT74556 Negative_regulation of Binding of Cnr1 4 0.59 1.13 2.67
108 INT11283 Negative_regulation of Grm1 5 0.57 0.8 2.63
109 INT166411 Positive_regulation of Negative_regulation of Cnr1 4 0.50 0.84 2.62
110 INT114513 Negative_regulation of Gene_expression of Gria2 8 0.48 0.89 2.61
111 INT91311 Gene_expression of Grm2 6 0.45 0.89 2.58
112 INT97807 Negative_regulation of Regulation of CNR1 2 0.09 0.89 2.51
113 INT125345 Positive_regulation of Localization of Cnr1 6 0.50 1.47 2.44
114 INT163544 Binding of Psen1 40 0.36 15.28 2.42
115 INT153733 Negative_regulation of Transcription of Gria2 1 0.47 0 2.39
116 INT166412 Protein_catabolism of Cnr1 4 0.99 0.9 2.37
117 INT169300 Phosphorylation of CNR1 4 0.57 2.15 2.31
118 INT93341 Localization of Prkaca 7 0.59 2.04 2.28
119 INT281073 Negative_regulation of Gene_expression of Gria2 4 0.56 0.72 2.18
120 INT101229 Positive_regulation of Positive_regulation of Gria2 5 0.41 2.2 2.16
121 INT103179 Regulation of Phosphorylation of Prkaca 6 0.45 0.79 2.15
122 INT181507 Positive_regulation of Psen1 22 0.49 7.59 2.04
123 INT169874 Positive_regulation of Gene_expression of Prkaca 11 0.38 1.64 2.01
124 INT98927 Localization of Grm1 4 0.71 0.42 1.97
125 INT67237 Binding of Grm1 7 0.00 1.49 1.94
126 INT193939 Binding of PSEN1 10 0.36 6.16 1.93
127 INT259164 Positive_regulation of Binding of Gria2 4 0.40 2 1.91
128 INT143277 Regulation of Phosphorylation of Gria2 5 0.60 1.91 1.87
129 INT161098 Regulation of Positive_regulation of CNR1 3 0.45 2.22 1.87
130 INT87973 Regulation of Binding of Cnr1 7 0.58 0.33 1.86
131 INT111070 Negative_regulation of Gene_expression of Psen1 17 0.42 9.47 1.77
132 INT186427 Negative_regulation of Negative_regulation of Prkaca 2 0.11 0.48 1.73
133 INT80162 Localization of Ucn 6 0.80 0.6 1.66
134 INT114508 Positive_regulation of Negative_regulation of Gria2 2 0.36 0.98 1.64
135 INT102371 Positive_regulation of Gene_expression of Grm2 2 0.35 0.41 1.63
136 INT264897 Negative_regulation of Negative_regulation of Cnr1 2 0.37 0.14 1.61
137 INT210002 Positive_regulation of Positive_regulation of Cnr1 3 0.47 1 1.54
138 INT108352 Regulation of Phosphorylation of Prkaca 8 0.59 0.68 1.53
139 INT282434 Regulation of Gene_expression of Psen1 9 0.50 2.85 1.52
140 INT218807 Transcription of Gria2 6 0.69 3.08 1.46
141 INT123232 Protein_catabolism of CNR1 2 0.58 0.72 1.45
142 INT152371 Regulation of Gene_expression of Grm1 2 0.42 0.54 1.4
143 INT351302 Regulation of Regulation of Cnr1 1 0.10 0.78 1.39
144 INT181509 Negative_regulation of Psen1 17 0.57 11.53 1.35
145 INT213894 Positive_regulation of Transcription of Cnr1 3 0.69 0.81 1.34
146 INT142288 Negative_regulation of Grm2 4 0.42 0.81 1.32
147 INT102369 Regulation of Positive_regulation of Grm2 1 0.11 0.54 1.27
148 INT59908 Negative_regulation of Gene_expression of CNR1 7 0.39 1.36 1.24
149 INT100921 Positive_regulation of Positive_regulation of Grm1 2 0.47 1.01 1.24
150 INT155346 Negative_regulation of Negative_regulation of Prkaca 4 0.21 1.34 1.23
151 INT162222 Positive_regulation of Positive_regulation of Gria2 3 0.38 0.64 1.19
152 INT264905 Positive_regulation of Binding of Cnr1 1 0.50 0.12 1.19
153 INT135761 Positive_regulation of Localization of Cnr1 1 0.45 1.25 1.1
154 INT257210 Positive_regulation of Phosphorylation of Gria2 3 0.41 0.65 1.07
155 INT220732 Protein_catabolism of Prkaca 3 0.11 0.61 1.02
156 INT240463 Negative_regulation of Phosphorylation of Prkaca 2 0.23 0.59 0.99
157 INT101336 Positive_regulation of Regulation of Cnr1 1 0.40 0 0.96
158 INT127440 Positive_regulation of Negative_regulation of Cnr1 2 0.50 1.57 0.94
159 INT91771 Positive_regulation of Gene_expression of PSEN1 13 0.49 8.93 0.93
160 INT123233 Negative_regulation of Protein_catabolism of CNR1 1 0.06 0.64 0.92
161 INT91310 Negative_regulation of Gene_expression of Grm2 2 0.33 0.2 0.87
162 INT91309 Transcription of Grm2 4 0.69 1.57 0.86
163 INT223641 Transcription of Grm1 3 0.69 1.4 0.83
164 INT80159 Gene_expression of Ucn 3 0.67 0.47 0.82
165 INT157555 Positive_regulation of Regulation of Gria2 2 0.28 0.26 0.82
166 INT237406 Positive_regulation of Binding of Psen1 1 0.29 0 0.8
167 INT120996 Positive_regulation of Gene_expression of Grm1 2 0.00 0.81 0.77
168 INT286313 Transcription of Psen1 9 0.70 2.26 0.76
169 INT135102 Positive_regulation of Localization of Prkaca 3 0.17 1.21 0.75
170 INT170715 Regulation of Grm2 2 0.20 0.34 0.75
171 INT218805 Negative_regulation of Phosphorylation of Gria2 2 0.38 1.51 0.73
172 INT132868 Negative_regulation of Negative_regulation of CNR1 1 0.23 0 0.68
173 INT93340 Negative_regulation of Localization of Prkaca 1 0.10 0 0.68
174 INT112649 Negative_regulation of Serpine2 10 0.43 1.41 0.66
175 INT353152 Localization of PRKACA 1 0.01 1.15 0.66
176 INT313381 Negative_regulation of Phosphorylation of CNR1 1 0.00 0.59 0.66
177 INT150753 Negative_regulation of Gene_expression of Prkaca 1 0.41 0.08 0.65
178 INT193557 Positive_regulation of Negative_regulation of Grm2 1 0.35 0 0.63
179 INT162221 Positive_regulation of Localization of Gria2 2 0.38 0.09 0.61
180 INT349122 Regulation of Phosphorylation of Gria2 1 0.28 0.57 0.61
181 INT353901 Negative_regulation of Negative_regulation of Grm1 1 0.40 0.67 0.61
182 INT131513 Regulation of Regulation of Cnr1 1 0.25 0.64 0.6
183 INT91054 Negative_regulation of Gene_expression of Grm1 2 0.36 0.19 0.59
184 INT69100 Regulation of Gene_expression of Serpine2 1 0.18 0 0.59
185 INT259166 Protein_catabolism of Gria2 2 0.70 0.47 0.58
186 INT95932 Negative_regulation of Negative_regulation of Gria2 3 0.35 0.75 0.56
187 INT80160 Negative_regulation of Ucn 2 0.58 0.29 0.56
188 INT132867 Negative_regulation of Transcription of CNR1 3 0.41 2.23 0.55
189 INT98814 Negative_regulation of Ucn 2 0.27 0.14 0.55
190 INT87975 Positive_regulation of Transcription of Cnr1 1 0.47 0 0.55
191 INT311190 Positive_regulation of Transcription of CNR1 1 0.48 2.02 0.55
192 INT85726 Negative_regulation of Localization of CNR1 1 0.01 0 0.55
193 INT122186 Binding of Ucn 2 0.23 0.37 0.53
194 INT217394 Regulation of Binding of PSEN1 1 0.44 1.58 0.53
195 INT141073 Positive_regulation of Protein_catabolism of CNR1 1 0.41 0.08 0.53
196 INT80163 Positive_regulation of Gene_expression of Ucn 1 0.50 0.41 0.52
197 INT230982 Positive_regulation of Transcription of Gria2 1 0.28 0.65 0.51
198 INT296431 Negative_regulation of Binding of Gria2 1 0.38 0.6 0.5
199 INT296434 Regulation of Regulation of Gria2 1 0.40 0.43 0.49
200 INT218813 Positive_regulation of Transcription of Gria2 1 0.39 1.19 0.48
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