GO:0052794

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Name exo-alpha-(2->3)-sialidase activity
Categary Function
Go Slim No
Go Link GO:0052794
Unique Molecular Interactions 17
Total Molecular Interactions 18
Total Single Events 337
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for exo-alpha-(2->3)-sialidase activity. They are ordered first by their pain relevance and then by number of times they were reported for exo-alpha-(2->3)-sialidase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT317538 Binding of Neu3 and Mors1 1 0.00 0 1.51
2 INT115272 Neu1 Positive_regulation of Coq10a 1 0.43 0.41 1.35
3 INT115271 Neu1 Positive_regulation of Coq10a 1 0.01 0.41 1.35
4 INT243682 IRF6 Positive_regulation of NEU2 1 0.01 0.18 0.43
5 INT61131 NEU2 Positive_regulation of CPQ 1 0.01 0 0.41
6 INT134615 Binding of Neu3 and Trpv1 1 0.01 0.06 0.11
7 INT214957 Vamp2 Regulation of Neu3 1 0.00 0 0.1
8 INT214954 Vamp1 Regulation of Neu3 1 0.00 0 0.1
9 INT14440 Binding of GLB1 and NEU1 1 0.00 0.09 0.05
10 INT280616 Binding of Neu2 and Mpl 1 0.00 0.12 0.04
11 INT327465 Binding of Cd4 and Neu1 1 0.06 0.73 0
12 INT191097 Neu1 Positive_regulation of Shc1 1 0.04 1.96 0
13 INT288588 Binding of Cav1 and Neu3 1 0.01 0 0
14 INT257341 Binding of Neu2 and Cyba 1 0.00 0.29 0
15 INT328422 Protein_catabolism of Neu1 Positive_regulation of Dnase2b 1 0.01 0.67 0
16 INT254044 Binding of BGLAP and NEU4 1 0.04 0.29 0
17 INT314679 NEU1 Negative_regulation of TP53 1 0.12 1.23 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for exo-alpha-(2->3)-sialidase activity. They are ordered first by their pain relevance and then by number of times they were reported in exo-alpha-(2->3)-sialidase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT78199 Gene_expression of Neu1 65 0.75 62.88 7.16
2 INT3731 Negative_regulation of Neu1 17 0.39 8.35 5.67
3 INT78524 Positive_regulation of Neu1 6 0.67 8.9 4.4
4 INT1701 Localization of Neu1 11 0.69 6.36 4.18
5 INT49006 Gene_expression of Neu3 13 0.08 1.22 3.63
6 INT127006 Phosphorylation of Neu3 3 0.02 0.43 3.61
7 INT118887 Positive_regulation of Neu3 3 0.01 8.39 2.62
8 INT39266 Negative_regulation of Localization of Neu1 6 0.30 4.66 2.6
9 INT3735 Localization of Neu1 9 0.73 3.83 2.46
10 INT2606 Localization of NEU1 10 0.41 4.6 1.82
11 INT104672 Negative_regulation of Neu3 4 0.14 4.67 1.82
12 INT41805 Localization of Neu3 4 0.10 0.33 1.28
13 INT291800 Positive_regulation of NEU2 2 0.01 0.57 1.26
14 INT80174 Positive_regulation of Gene_expression of Neu1 23 0.37 17.82 1.12
15 INT62377 Regulation of Neu2 2 0.01 0.51 1.11
16 INT127003 Binding of Neu3 7 0.02 1.57 1.05
17 INT185501 Localization of NEU2 4 0.02 1.08 1.04
18 INT127005 Positive_regulation of Localization of Neu3 1 0.02 0.33 0.97
19 INT2607 Negative_regulation of Localization of NEU1 3 0.30 1.52 0.88
20 INT3732 Negative_regulation of Localization of Neu1 3 0.01 1 0.75
21 INT58866 Regulation of Neu1 3 0.08 1.13 0.75
22 INT181867 Positive_regulation of Positive_regulation of Neu1 1 0.49 0.93 0.72
23 INT72654 Regulation of Localization of Neu1 1 0.02 0.34 0.72
24 INT118886 Regulation of Positive_regulation of Neu3 1 0.01 0.61 0.72
25 INT20316 Regulation of Neu1 1 0.05 0.19 0.7
26 INT166920 Binding of Neu1 2 0.21 2.67 0.63
27 INT45208 Regulation of NEU1 2 0.10 3.79 0.58
28 INT71414 Binding of Neu2 1 0.02 0 0.57
29 INT214945 Regulation of Neu3 11 0.01 1.65 0.51
30 INT67848 Localization of Neu2 5 0.07 1.17 0.51
31 INT14450 Binding of NEU1 7 0.14 5.1 0.5
32 INT45878 Gene_expression of NEU1 14 0.65 7.28 0.47
33 INT2610 Positive_regulation of Localization of NEU1 2 0.12 0.7 0.44
34 INT350224 Regulation of NEU2 1 0.00 0.25 0.35
35 INT55784 Negative_regulation of Neu1 4 0.24 1.93 0.33
36 INT32138 Positive_regulation of Neu2 3 0.02 0.86 0.33
37 INT350226 Negative_regulation of Positive_regulation of NEU2 1 0.00 0.14 0.31
38 INT83288 Negative_regulation of NEU4 12 0.51 3.58 0.28
39 INT350225 Positive_regulation of Positive_regulation of NEU2 1 0.00 0.17 0.26
40 INT3525 Protein_catabolism of NEU1 2 0.58 0.62 0.23
41 INT45210 Regulation of Localization of NEU1 1 0.06 0.15 0.22
42 INT350222 Positive_regulation of Localization of NEU2 1 0.00 0 0.17
43 INT46192 Gene_expression of Neu1 1 0.03 0.42 0.16
44 INT46193 Positive_regulation of Gene_expression of Neu1 1 0.02 0.42 0.16
45 INT221134 Positive_regulation of NEU1 1 0.19 2.51 0.11
46 INT94176 Negative_regulation of NEU1 1 0.11 1.09 0.11
47 INT125096 Gene_expression of NEU2 2 0.03 0.14 0.1
48 INT3734 Regulation of Localization of Neu1 1 0.00 0.07 0.09
49 INT155113 Positive_regulation of Gene_expression of NEU1 1 0.29 0.45 0.08
50 INT221135 Regulation of Binding of NEU1 1 0.17 0.61 0.06
51 INT115996 Gene_expression of Neu2 3 0.52 0.91 0.03
52 INT224233 Phosphorylation of NEU2 1 0.01 0.7 0.03
53 INT237342 Regulation of Binding of Neu3 1 0.00 0.43 0.03
54 INT300175 Positive_regulation of NEU4 1 0.01 0.48 0
55 INT283547 Positive_regulation of Regulation of Neu3 1 0.01 0 0
56 INT328421 Protein_catabolism of Neu1 1 0.02 0.67 0
57 INT208283 Negative_regulation of Gene_expression of Neu2 1 0.01 0.33 0
58 INT300176 Localization of NEU4 1 0.01 0.47 0
59 INT115997 Regulation of Gene_expression of Neu2 1 0.23 0 0
60 INT328419 Positive_regulation of Protein_catabolism of Neu1 1 0.01 0.67 0
61 INT247407 Gene_expression of NEU4 1 0.20 0.22 0
62 INT83289 Binding of NEU4 1 0.02 0.1 0
63 INT134705 Negative_regulation of NEU2 1 0.12 0.47 0
64 INT300168 Binding of Neu1 1 0.07 0.27 0
65 INT229442 Negative_regulation of Localization of Neu2 1 0.01 0.3 0
66 INT232210 Regulation of Gene_expression of Neu1 1 0.06 0.97 0
67 INT113297 Positive_regulation of Neu1 1 0.00 0.67 0
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