GO:0055008

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Name cardiac muscle tissue morphogenesis
Categary Process
Go Slim No
Go Link GO:0055008
Unique Molecular Interactions 94
Total Molecular Interactions 121
Total Single Events 726
Pain Genes Associated 13

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cardiac muscle tissue morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported for cardiac muscle tissue morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT89878 Pdyn Positive_regulation of Gene_expression of Nkx2-5 1 0.35 0 1.29
2 INT210783 Bmp2 Positive_regulation of Tnip1 1 0.40 0.53 0.94
3 INT210791 Bmp2 Positive_regulation of Net1 1 0.38 0.52 0.93
4 INT210799 Bmp2 Positive_regulation of B2m 1 0.35 0.52 0.92
5 INT89877 Pdyn Positive_regulation of Nkx2-5 1 0.11 0 0.64
6 INT248172 Epo Regulation of Cysltr1 1 0.01 0.74 0.63
7 INT248170 Epo Regulation of Ltp 1 0.11 0.74 0.62
8 INT184111 Epo Positive_regulation of Il7 1 0.06 0.26 0.52
9 INT184130 Epo Positive_regulation of Stat5a 1 0.31 0.26 0.52
10 INT184088 Epo Positive_regulation of Il2 1 0.07 0.26 0.52
11 INT210793 Bmp2 Positive_regulation of Tsc22d3 1 0.32 0.26 0.46
12 INT224700 TNF Positive_regulation of Angpt1 1 0.00 0.63 0.34
13 INT224687 Il1 Positive_regulation of Bmp2 1 0.00 0.3 0.31
14 INT166165 Binding of TGFB3 and Bmp2 1 0.00 0 0.3
15 INT109067 Pdyn Positive_regulation of Gene_expression of NKX2-5 1 0.01 0 0.29
16 INT182817 EEF1A2 Positive_regulation of BMP2 1 0.26 1.62 0.28
17 INT271445 Thy1 Regulation of Acta2 1 0.02 0.62 0.25
18 INT248171 Epo Regulation of Sult1a1 1 0.08 0.11 0.21
19 INT343475 Epo Regulation of Akt1 1 0.18 0.41 0.16
20 INT343478 Epo Regulation of Gene_expression of Akt1 1 0.40 0.41 0.16
21 INT343484 Epo Regulation of Gene_expression of VEGFA 1 0.24 0.41 0.16
22 INT198671 HIF1A Regulation of Positive_regulation of Epo 1 0.00 1.37 0.13
23 INT343472 Epo Positive_regulation of Gene_expression of Mmp2 1 0.15 0.62 0.12
24 INT326974 BMP2 Positive_regulation of Gene_expression of COL2A1 1 0.07 0.27 0.11
25 INT208938 Positive_regulation of Tacr1 Positive_regulation of Nkx2-5 1 0.17 0 0.1
26 INT200811 Epo Positive_regulation of Akt1 2 0.30 1.77 0.09
27 INT343486 Epo Positive_regulation of Localization of VEGFA 1 0.25 0.41 0.09
28 INT238038 Binding of BMP2 and OPLL 1 0.20 2.45 0.09
29 INT343485 Epo Positive_regulation of Gene_expression of VEGFA 1 0.25 0.51 0.09
30 INT192249 Angpt1 Positive_regulation of Localization of NOS3 1 0.01 0.46 0.09
31 INT192248 Angpt1 Positive_regulation of NOS3 1 0.01 0.46 0.09
32 INT192250 Positive_regulation of Angpt1 Positive_regulation of NOS3 1 0.01 0.46 0.09
33 INT208943 Nfkb1 Positive_regulation of Nkx2-5 1 0.11 0.38 0.08
34 INT297968 Positive_regulation of Binding of BMP2 and IL17C 1 0.21 0.26 0.08
35 INT297970 Binding of BMP2 and IL17C 1 0.15 0.26 0.08
36 INT343481 Epo Positive_regulation of Igf1 1 0.15 0.31 0.06
37 INT343477 Epo Positive_regulation of Pdgfb 1 0.11 0.31 0.06
38 INT295122 Bmp2 Regulation of Grxcr1 1 0.02 0.66 0.06
39 INT343479 Epo Positive_regulation of Fgf2 1 0.33 0.3 0.06
40 INT343480 Epo Positive_regulation of Mmp2 1 0.15 0.31 0.06
41 INT295120 Bmp2 Regulation of Transcription of Pou1f1 1 0.24 0.66 0.06
42 INT343471 Epo Positive_regulation of Gene_expression of Pdgfb 1 0.11 0.31 0.06
43 INT226043 Epo Positive_regulation of Ecm1 1 0.04 1.35 0.05
44 INT254161 Epo Positive_regulation of Nos2 1 0.37 0.54 0.05
45 INT254162 Epo Positive_regulation of NOS1 1 0.01 0.53 0.05
46 INT208945 Nkx2-5 Positive_regulation of Gene_expression of Nppa 1 0.03 0.33 0.05
47 INT305383 Binding of NKX2-5 and FLNA 1 0.10 0.7 0.04
48 INT178501 Angpt1 Positive_regulation of Tek 1 0.06 0.78 0.04
49 INT298703 Angpt1 Regulation of Tek 1 0.12 0.27 0.03
50 INT200809 Binding of Akt1 and Epo 1 0.23 0.98 0.03
51 INT343487 Epo Positive_regulation of Gene_expression of EPOR 1 0.76 0.32 0.03
52 INT173613 BMP2 Positive_regulation of INCENP 1 0.00 0.28 0.03
53 INT200814 Epo Positive_regulation of Lyn 1 0.36 1.42 0.03
54 INT287233 PDLIM7 Positive_regulation of Gene_expression of BMP2 1 0.07 0.12 0.03
55 INT200815 Binding of Epo and Jak2 1 0.36 0.98 0.03
56 INT343476 Epo Positive_regulation of Kdr 1 0.11 0.31 0.03
57 INT200820 Epo Positive_regulation of Src 1 0.25 1.41 0.03
58 INT343474 Epo Positive_regulation of Gene_expression of Kdr 1 0.11 0.32 0.03
59 INT343488 Epo Positive_regulation of EPOR 1 0.24 0.31 0.03
60 INT189554 Binding of HIF1A and Positive_regulation of EGLN1 1 0.04 0.86 0
61 INT274435 Binding of Zfpm2 and Mir130a 1 0.30 0.26 0
62 INT343999 INCENP Positive_regulation of BMP2 1 0.01 0 0
63 INT278021 BMP2 Positive_regulation of Gene_expression of RUNX1T1 1 0.02 0.5 0
64 INT334644 Binding of PSEN1 and TTN 1 0.01 0 0
65 INT189555 EGLN1 Regulation of Gene_expression of VEGFA 1 0.07 0.57 0
66 INT288617 Binding of CSF2RB and Epor 1 0.19 0.73 0
67 INT205451 Binding of BMP2 and Acvr2a 1 0.02 0.05 0
68 INT303342 Binding of NPAT and TCAP 1 0.40 0 0
69 INT343473 Epo Positive_regulation of Gene_expression of Akt1 1 0.45 0.05 0
70 INT200819 Epo Positive_regulation of Gene_expression of Jak2 1 0.49 0.91 0
71 INT274432 Mir130a Regulation of Zfpm2 1 0.22 0.08 0
72 INT303404 Binding of TCAP and Jag1 1 0.39 0 0
73 INT247575 Binding of Epo and Hif1a 1 0.09 1.24 0
74 INT274431 Mir130a Regulation of Gene_expression of Zfpm2 1 0.50 0.79 0
75 INT220286 Epo Regulation of hb 1 0.23 0.21 0
76 INT109817 Ace2 Positive_regulation of Angpt1 1 0.05 0.31 0
77 INT196023 Bmp2 Negative_regulation of Gene_expression of Bmp4 1 0.09 0.07 0
78 INT205410 Binding of BMP2 and BMPR2 1 0.07 0.05 0
79 INT189552 EGLN1 Positive_regulation of HIF1A 1 0.05 0.98 0
80 INT344001 INCENP Positive_regulation of Gene_expression of BMP2 1 0.01 0 0
81 INT274434 Binding of Gata4 and Zfpm2 1 0.12 0.56 0
82 INT196021 Bmp2 Positive_regulation of Gene_expression of Bmp4 1 0.09 0.08 0
83 INT176096 Regulation of Binding of Angpt1 and Tek 1 0.07 0.54 0
84 INT295129 Proc Regulation of Bmp2 1 0.00 0.48 0
85 INT176097 Binding of Angpt1 and Tek 1 0.06 0.48 0
86 INT272520 Gene_expression of Dmpk Positive_regulation of Positive_regulation of Nkx2-5 1 0.02 0.43 0
87 INT274433 Binding of Zfpm2 and Uts2r 1 0.08 0.17 0
88 INT274436 Mir130a Regulation of Transcription of Zfpm2 1 0.22 0 0
89 INT270460 Shh Positive_regulation of Gene_expression of Angpt1 1 0.04 0.08 0
90 INT272521 Binding of DMPK and Nkx2-5 1 0.01 0.42 0
91 INT321594 Bmp2 Regulation of Gene_expression of Lxn 1 0.42 1.71 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cardiac muscle tissue morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported in cardiac muscle tissue morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT137702 Binding of TTN 7 0.35 4.48 3.62
2 INT85809 Gene_expression of BMP2 46 0.78 9.91 3.05
3 INT96423 Gene_expression of Bmp2 61 0.78 25.07 3.01
4 INT178030 Localization of Epo 11 0.78 6.03 1.86
5 INT144993 Gene_expression of Epor 4 0.75 5.7 1.61
6 INT89865 Gene_expression of Nkx2-5 14 0.75 2.99 1.58
7 INT144992 Positive_regulation of Epor 3 0.67 2.09 1.57
8 INT178029 Gene_expression of Epo 25 0.76 14.98 1.46
9 INT130014 Positive_regulation of BMP2 11 0.66 5.34 1.42
10 INT70619 Regulation of Bmp2 6 0.60 3.1 1.29
11 INT104636 Regulation of TTN 2 0.33 0 1.29
12 INT178494 Gene_expression of Angpt1 10 0.37 9.77 1.28
13 INT178023 Regulation of Epo 11 0.45 3.87 1.22
14 INT96424 Transcription of Bmp2 6 0.69 6.34 1.11
15 INT160538 Binding of Bmp2 4 0.40 2.08 1.07
16 INT161716 Localization of Nkx2-5 2 0.74 2.17 1.02
17 INT109075 Positive_regulation of Transcription of NKX2-5 1 0.67 0 1.02
18 INT109074 Transcription of NKX2-5 1 0.69 0 1.01
19 INT71916 Gene_expression of TTN 9 0.75 1.69 0.97
20 INT178026 Positive_regulation of Epo 12 0.70 8.14 0.95
21 INT114664 Binding of BMP2 12 0.37 6.54 0.91
22 INT109062 Gene_expression of NKX2-5 7 0.75 3.31 0.82
23 INT288606 Negative_regulation of Gene_expression of Epor 1 0.41 3.73 0.8
24 INT161034 Gene_expression of Acta2 3 0.75 2.69 0.79
25 INT89861 Negative_regulation of Nkx2-5 3 0.19 0.12 0.63
26 INT39728 Regulation of TCAP 1 0.00 0 0.61
27 INT238049 Positive_regulation of Gene_expression of BMP2 8 0.51 2.06 0.59
28 INT248166 Protein_catabolism of Epo 1 0.89 0.71 0.59
29 INT89869 Negative_regulation of Gene_expression of Nkx2-5 1 0.41 0 0.56
30 INT85808 Localization of BMP2 7 0.77 1.94 0.51
31 INT305390 Negative_regulation of NKX2-5 2 0.37 2.24 0.49
32 INT145301 Regulation of Gene_expression of Bmp2 1 0.32 1.16 0.48
33 INT120086 Gene_expression of Bmp2 5 0.27 2.34 0.43
34 INT96909 Regulation of Angpt1 2 0.17 0.37 0.43
35 INT178497 Positive_regulation of Gene_expression of Angpt1 4 0.19 3.65 0.39
36 INT288608 Localization of Epor 1 0.73 3.34 0.37
37 INT241717 Regulation of Localization of Epo 1 0.10 0.55 0.37
38 INT84945 Transcription of BMP2 5 0.61 1.8 0.36
39 INT196026 Positive_regulation of Gene_expression of Bmp2 14 0.69 3.19 0.35
40 INT226037 Binding of Epo 5 0.36 2.99 0.32
41 INT208915 Positive_regulation of Nkx2-5 3 0.29 1.02 0.25
42 INT181914 Positive_regulation of EGLN1 1 0.36 2.03 0.25
43 INT145305 Positive_regulation of Bmp2 12 0.69 8.65 0.24
44 INT271438 Regulation of Acta2 1 0.04 0.61 0.24
45 INT96908 Protein_catabolism of Angpt1 1 0.41 0.26 0.24
46 INT109699 Regulation of BMP2 5 0.43 2.21 0.23
47 INT220396 Negative_regulation of Angpt1 4 0.26 1.64 0.23
48 INT288607 Binding of Epor 1 0.36 0.44 0.21
49 INT305392 Binding of NKX2-5 1 0.22 0.93 0.21
50 INT248168 Positive_regulation of Transcription of Epor 1 0.36 0 0.19
51 INT248169 Positive_regulation of Transcription of Epo 1 0.50 0 0.19
52 INT248165 Transcription of Epo 1 0.69 0 0.19
53 INT248167 Transcription of Epor 1 0.49 0 0.19
54 INT200796 Negative_regulation of Epo 7 0.43 3.22 0.18
55 INT148064 Localization of Bmp2 2 0.29 0.14 0.17
56 INT208925 Positive_regulation of Localization of Nkx2-5 1 0.21 0.14 0.16
57 INT106010 Positive_regulation of Bmp2 2 0.26 0.91 0.15
58 INT288611 Protein_catabolism of Epor 1 0.64 0.3 0.14
59 INT228608 Positive_regulation of Gene_expression of Epo 5 0.68 2.85 0.13
60 INT146415 Regulation of Nkx2-5 3 0.44 0.91 0.13
61 INT189614 Gene_expression of EGLN1 6 0.49 4.3 0.12
62 INT254992 Negative_regulation of Gene_expression of BMP2 3 0.34 0.56 0.11
63 INT238044 Positive_regulation of Transcription of BMP2 2 0.43 0.83 0.11
64 INT288610 Negative_regulation of Epor 1 0.41 0.9 0.11
65 INT208922 Transcription of Nkx2-5 2 0.29 0.36 0.1
66 INT323415 Regulation of NKX2-5 1 0.39 0.71 0.1
67 INT208917 Positive_regulation of Transcription of Nkx2-5 1 0.21 0 0.1
68 INT323416 Localization of NKX2-5 1 0.65 1.75 0.1
69 INT326976 Regulation of Localization of BMP2 1 0.59 0.08 0.1
70 INT196035 Localization of Bmp2 3 0.63 0.23 0.09
71 INT208918 Positive_regulation of Gene_expression of Nkx2-5 3 0.23 0.48 0.09
72 INT278036 Negative_regulation of BMP2 2 0.34 0.64 0.09
73 INT355176 Regulation of Binding of TTN 1 0.29 0.78 0.09
74 INT114663 Regulation of Binding of BMP2 1 0.38 0.19 0.09
75 INT343457 Regulation of Binding of Epo 1 0.44 0 0.09
76 INT163072 Regulation of Binding of Bmp2 1 0.30 0.52 0.08
77 INT197520 Positive_regulation of Gene_expression of TTN 1 0.09 0 0.08
78 INT305387 Positive_regulation of Gene_expression of NKX2-5 1 0.31 0.72 0.07
79 INT158616 Localization of EGLN1 1 0.73 0.54 0.06
80 INT196025 Negative_regulation of Bmp2 2 0.34 0.14 0.05
81 INT229753 Positive_regulation of Gene_expression of Bmp2 2 0.11 1.22 0.04
82 INT287236 Positive_regulation of Positive_regulation of BMP2 1 0.29 0.08 0.04
83 INT226039 Positive_regulation of Positive_regulation of Epo 1 0.45 1.38 0.04
84 INT265497 Positive_regulation of TTN 2 0.04 0 0.03
85 INT220284 Phosphorylation of Epo 2 0.63 1.2 0.03
86 INT189593 Regulation of Gene_expression of BMP2 2 0.33 0.8 0
87 INT145300 Positive_regulation of Positive_regulation of Bmp2 2 0.34 1.03 0
88 INT196031 Binding of Bmp2 1 0.16 0 0
89 INT274420 Positive_regulation of Gene_expression of Zfpm2 1 0.49 0.51 0
90 INT189577 Negative_regulation of EGLN1 1 0.31 1.73 0
91 INT189603 Negative_regulation of Transcription of EGLN1 1 0.31 0.94 0
92 INT278735 Negative_regulation of Gene_expression of Bmp2 1 0.43 0.06 0
93 INT274412 Transcription of Zfpm2 1 0.53 0 0
94 INT274418 Regulation of Gene_expression of Zfpm2 1 0.45 1.42 0
95 INT274417 Negative_regulation of Zfpm2 1 0.43 6.99 0
96 INT274428 Regulation of Binding of Zfpm2 1 0.45 0.15 0
97 INT197519 Positive_regulation of Regulation of TTN 1 0.09 0 0
98 INT274405 Gene_expression of Zfpm2 1 0.77 6.51 0
99 INT274425 Negative_regulation of Gene_expression of Zfpm2 1 0.42 0.06 0
100 INT278737 Positive_regulation of Transcription of Bmp2 1 0.47 1.4 0
101 INT120087 Negative_regulation of Gene_expression of Bmp2 1 0.11 0.14 0
102 INT274411 Positive_regulation of Zfpm2 1 0.46 0.53 0
103 INT189605 Regulation of EGLN1 1 0.33 1.65 0
104 INT189617 Transcription of EGLN1 1 0.50 0.94 0
105 INT303380 Protein_catabolism of TCAP 1 0.64 0 0
106 INT197522 Localization of TTN 1 0.14 0 0
107 INT274414 Regulation of Zfpm2 1 0.61 0.59 0
108 INT278040 Negative_regulation of Localization of BMP2 1 0.32 0.32 0
109 INT228609 Negative_regulation of Localization of Epo 1 0.42 0.62 0
110 INT189572 Positive_regulation of Gene_expression of EGLN1 1 0.34 0.92 0
111 INT274408 Binding of Zfpm2 1 0.37 0.77 0
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