GO:0055072

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Name iron ion homeostasis
Categary Process
Go Slim No
Go Link GO:0055072
Unique Molecular Interactions 229
Total Molecular Interactions 318
Total Single Events 3840
Pain Genes Associated 24

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for iron ion homeostasis. They are ordered first by their pain relevance and then by number of times they were reported for iron ion homeostasis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT132465 Ltf Positive_regulation of Nos1 1 0.35 0.05 1.24
2 INT283426 Binding of Lcn2 and Nt5e 1 0.08 5.8 1.24
3 INT111221 MMEL1 Negative_regulation of HMOX1 1 0.01 1 1.16
4 INT231769 TNF Negative_regulation of Gene_expression of HMOX1 1 0.26 4.75 1.15
5 INT132464 Ltf Negative_regulation of Positive_regulation of Nos1 1 0.33 0 1.03
6 INT152490 Slc40a1 Negative_regulation of Faah 1 0.01 0.73 0.98
7 INT147474 Nfe2l2 Positive_regulation of Hmox1 1 0.43 0.38 0.9
8 INT209043 Binding of Fn1 and Slc11a1 3 0.03 1.91 0.78
9 INT81299 Ifng Positive_regulation of Gene_expression of Hmox1 1 0.52 0.75 0.76
10 INT99743 Olr1742 Regulation of Gene_expression of Hmox1 1 0.00 0 0.68
11 INT86519 Binding of Hmox1 and Hmox2 1 0.08 0.1 0.66
12 INT103868 IFNG Positive_regulation of Hmox1 1 0.09 0.83 0.65
13 INT209063 Slc11a1 Positive_regulation of Il17a 1 0.11 0.4 0.65
14 INT99744 Calca Positive_regulation of Positive_regulation of Hmox1 1 0.48 0 0.64
15 INT103870 IRF6 Positive_regulation of Hmox1 1 0.14 0.83 0.64
16 INT158362 Tnf Positive_regulation of Steap4 1 0.55 1.6 0.61
17 INT40901 Trf Regulation of Localization of POMC 1 0.07 0.56 0.6
18 INT81303 Tlr4 Positive_regulation of Gene_expression of Hmox1 1 0.03 0.55 0.56
19 INT270044 Il10 Positive_regulation of Positive_regulation of Hmox1 1 0.20 1.59 0.53
20 INT283434 Lcn2 Positive_regulation of Localization of IL8 1 0.07 1.33 0.51
21 INT117483 SFXN3 Negative_regulation of THRB 1 0.15 0.15 0.51
22 INT350076 Positive_regulation of Hmox1 Negative_regulation of Gene_expression of Ptger2 1 0.02 1.29 0.5
23 INT197380 Tbs1 Positive_regulation of Sfxn1 1 0.00 0 0.5
24 INT145435 Binding of CPOX and HMOX1 1 0.01 0.42 0.49
25 INT209046 Slc11a1 Positive_regulation of Regulation of Tlr4 1 0.07 0.09 0.48
26 INT145434 Binding of HMOX1 and PTGS2 1 0.02 0.41 0.47
27 INT148466 Ccl4 Positive_regulation of Hmox1 1 0.28 0.06 0.47
28 INT242402 Negative_regulation of Bdkrb1 Positive_regulation of Hmox1 1 0.17 1.44 0.45
29 INT103871 Negative_regulation of IRF6 Positive_regulation of Hmox1 1 0.12 0.61 0.45
30 INT209049 Slc11a1 Positive_regulation of Localization of Il12a 1 0.04 0.09 0.44
31 INT165677 NFE2L2 Negative_regulation of Positive_regulation of HMOX1 1 0.40 0.32 0.44
32 INT165678 NFE2L2 Negative_regulation of HMOX1 1 0.40 0.31 0.43
33 INT216881 Binding of Apoc4 and Hmox1 1 0.01 1.78 0.4
34 INT147473 Nfe2l2 Positive_regulation of Gene_expression of Hmox1 1 0.74 0.49 0.39
35 INT293204 Binding of CNR2 and SLC25A37 1 0.01 0 0.36
36 INT209047 Slc11a1 Positive_regulation of Localization of Il10 1 0.10 0.52 0.36
37 INT147472 co Positive_regulation of Gene_expression of Hmox1 1 0.01 0.57 0.36
38 INT272412 VSX1 Positive_regulation of Gene_expression of Slc11a1 1 0.00 0.57 0.35
39 INT91751 Binding of PTGS2 and Hmox1 1 0.00 0.21 0.27
40 INT262809 Il10 Positive_regulation of Regulation of Slc11a1 1 0.17 1.12 0.27
41 INT351391 Binding of Sod2 and Gtf3a 1 0.00 0.18 0.27
42 INT262810 Slc11a1 Positive_regulation of Gene_expression of Il10 1 0.20 0.97 0.27
43 INT270046 Ido1 Positive_regulation of Positive_regulation of Hmox1 1 0.15 0.8 0.27
44 INT216880 Apoc4 Positive_regulation of Hmox1 1 0.03 1.06 0.25
45 INT349652 Positive_regulation of Hmox1 Negative_regulation of Positive_regulation of Itk 1 0.01 0.85 0.25
46 INT209066 Slc11a1 Positive_regulation of Binding of TNF 1 0.01 1.11 0.24
47 INT226911 Slc11a1 Positive_regulation of Gene_expression of Il6 1 0.09 1.12 0.24
48 INT350099 Gene_expression of Hmox1 Positive_regulation of Gene_expression of MRXS5 1 0.01 0.51 0.24
49 INT328228 Binding of Cpox and Hmox1 1 0.03 0.83 0.23
50 INT350065 Gene_expression of Hmox1 Negative_regulation of Gene_expression of Tlr4 1 0.18 0.35 0.22
51 INT260397 Positive_regulation of Hmox1 Positive_regulation of Gene_expression of Adipoq 1 0.37 0.78 0.22
52 INT103867 SFTPA1 Positive_regulation of Hmox1 1 0.00 0.35 0.22
53 INT64340 Zc3h15 Negative_regulation of Hmox1 1 0.12 0.47 0.22
54 INT350078 Hmox1 Negative_regulation of Gene_expression of Ptger2 1 0.02 0.35 0.22
55 INT103869 Binding of IRF6 and Positive_regulation of Hmox1 1 0.10 0.27 0.21
56 INT309513 Binding of Xrcc6 and Htt 1 0.30 3.69 0.21
57 INT276241 Slc11a1 Positive_regulation of Gene_expression of Hand1 1 0.02 1.24 0.21
58 INT349647 Eif2ak1 Positive_regulation of Positive_regulation of Hmox1 1 0.00 1.07 0.2
59 INT350096 Hmox1 Negative_regulation of Gene_expression of MRXS5 1 0.01 0.32 0.2
60 INT158466 FECH Negative_regulation of Fech 1 0.23 0.57 0.2
61 INT283431 Lcn2 Regulation of Gene_expression of Cxcr1 1 0.01 0.22 0.2
62 INT266646 HMOX2 Regulation of Gene_expression of Hmox1 1 0.00 0.87 0.2
63 INT349646 Eif2ak1 Regulation of Gene_expression of Hmox1 1 0.00 0.78 0.2
64 INT260394 Positive_regulation of Hmox1 Positive_regulation of Adipoq 1 0.37 0.78 0.19
65 INT199191 Negative_regulation of Sod2 Positive_regulation of Ros1 1 0.08 0 0.19
66 INT199192 Gnat3 Positive_regulation of Hmox1 1 0.27 0.23 0.19
67 INT319173 TXN Positive_regulation of Gene_expression of SOD2 1 0.23 0.1 0.18
68 INT81296 Positive_regulation of Pparg Regulation of Gene_expression of Hmox1 1 0.25 0.17 0.17
69 INT351565 Binding of LPAR6 and SFXN5 1 0.00 1.1 0.17
70 INT178269 Slc11a2 Regulation of a 1 0.06 0.97 0.16
71 INT350072 Ptger2 Positive_regulation of Hmox1 1 0.02 0.2 0.15
72 INT226901 Slc11a1 Regulation of Hist1h3f 1 0.02 0.41 0.15
73 INT231757 TLR4 Positive_regulation of Negative_regulation of HMOX1 1 0.26 1.37 0.15
74 INT283428 Negative_regulation of Binding of Lcn2 and Nt5e 1 0.06 1.09 0.15
75 INT216882 Tlr4 Positive_regulation of Hmox1 1 0.17 0.19 0.15
76 INT350081 Pik3r1 Positive_regulation of Hmox1 1 0.07 0.2 0.15
77 INT350069 Prkaca Positive_regulation of Hmox1 1 0.05 0.2 0.15
78 INT199195 Gnat3 Regulation of Transcription of Hmox1 1 0.24 0.12 0.14
79 INT204159 Slc11a2 Regulation of Gene_expression of HAMP 1 0.11 1.08 0.14
80 INT295267 Binding of Hmox1 and Gtf3a 1 0.01 0.49 0.13
81 INT295261 Binding of Hmox1 and Nfe2l2 1 0.17 0.49 0.13
82 INT75739 Ltf Negative_regulation of Il6 1 0.35 0.39 0.13
83 INT288701 Epas1 Regulation of Transcription of Slc11a2 1 0.29 0.38 0.13
84 INT295264 Positive_regulation of Binding of Hmox1 and Nfe2l2 1 0.25 0.5 0.13
85 INT75738 Ltf Negative_regulation of Tnf 1 0.31 0.39 0.13
86 INT231761 TNF Negative_regulation of HMOX1 1 0.19 1.2 0.12
87 INT75737 Ltf Negative_regulation of Gene_expression of Il6 1 0.35 0.32 0.12
88 INT317162 Binding of Bdnf and Htt 1 0.51 0.2 0.12
89 INT226899 Slc11a1 Positive_regulation of Localization of Gtf3a 1 0.00 0.54 0.11
90 INT204883 gr Negative_regulation of Lcn2 1 0.07 0.15 0.11
91 INT226910 Slc11a1 Positive_regulation of Localization of Nfkb1 1 0.11 0.62 0.11
92 INT231764 TLR4 Negative_regulation of HMOX1 1 0.27 1.54 0.11
93 INT266900 Gene_expression of Sod2 Negative_regulation of Gene_expression of Sod1 1 0.11 0.41 0.11
94 INT231768 Binding of HMOX1 and TLR4 1 0.23 0.95 0.11
95 INT319315 Binding of Ap2a2 and Htt 1 0.28 0.64 0.11
96 INT231772 TNF Positive_regulation of Gene_expression of HMOX1 1 0.21 0.96 0.1
97 INT311009 Binding of LCN2 and SNRPB 1 0.01 0.35 0.1
98 INT231773 IRF6 Negative_regulation of Gene_expression of HMOX1 1 0.06 1.27 0.09
99 INT283427 Lcn2 Positive_regulation of Nt5e 1 0.08 0.21 0.09
100 INT226912 Slc11a1 Positive_regulation of Localization of IL8 1 0.05 0.58 0.08
101 INT318387 Binding of Slc40a1 and Hrct1 1 0.02 0.88 0.08
102 INT309390 Gene_expression of Sod2 Negative_regulation of Nos3 1 0.31 0.2 0.08
103 INT201456 Hmox1 Positive_regulation of Gene_expression of Bcl2 1 0.06 0.74 0.08
104 INT201736 Nfkb1 Positive_regulation of Transcription of Sod2 1 0.01 0.93 0.08
105 INT302131 Negative_regulation of SOD2 Regulation of BAK1 1 0.09 1.22 0.07
106 INT226913 Slc11a1 Positive_regulation of Gene_expression of IL8 1 0.05 0.63 0.07
107 INT302128 SOD2 Regulation of BAK1 1 0.09 1.22 0.07
108 INT260392 Hmox1 Positive_regulation of Adipoq 1 0.32 0.65 0.07
109 INT345292 Binding of Lcn2 and Havcr1 1 0.00 1.17 0.07
110 INT244290 Il6 Positive_regulation of Hmox1 1 0.38 0.09 0.07
111 INT283425 Lcn2 Positive_regulation of Gene_expression of Nt5e 1 0.07 0.13 0.07
112 INT297735 Cbr1 Positive_regulation of Sod2 1 0.11 1.28 0.07
113 INT345297 Binding of NAGLU and Lcn2 1 0.01 1.24 0.07
114 INT244291 Nos2 Positive_regulation of Positive_regulation of Hmox1 1 0.34 0.07 0.07
115 INT243119 Binding of amd and Sod2 1 0.29 3.25 0.06
116 INT23749 Ltf Positive_regulation of Sct 1 0.02 0.33 0.06
117 INT231760 TNF Positive_regulation of Protein_catabolism of HMOX1 1 0.31 0.41 0.06
118 INT349645 Eif2ak1 Positive_regulation of Hmox1 1 0.00 0.18 0.05
119 INT231758 IRF6 Regulation of Gene_expression of HMOX1 1 0.08 0.23 0.05
120 INT317181 Binding of Htt and Uts2r 1 0.04 0 0.05
121 INT341375 Sod2 Regulation of Bcl2 1 0.08 1.96 0.05
122 INT231766 TLR4 Negative_regulation of Gene_expression of HMOX1 1 0.28 0.71 0.05
123 INT338827 Binding of Slc40a1 and HAMP 1 0.00 0.27 0.05
124 INT231771 Binding of HMOX1 and TNF 2 0.14 1.41 0.04
125 INT231759 IL10 Positive_regulation of Gene_expression of HMOX1 1 0.06 0.7 0.04
126 INT266902 Nfe2l2 Positive_regulation of Sod2 1 0.16 0.19 0.04
127 INT326625 Binding of ALB and Trf 1 0.01 0.64 0.04
128 INT349648 Eif2ak1 Positive_regulation of Gene_expression of Hmox1 1 0.00 0.17 0.04
129 INT227333 Il2 Positive_regulation of Hmox1 1 0.05 0.93 0.04
130 INT226897 Binding of Slc11a1 and Tg(CAG-EGFP)D4Nagy 1 0.01 0.17 0.04
131 INT231775 TLR4 Regulation of Gene_expression of HMOX1 1 0.29 0.68 0.04
132 INT266898 Gtf3a Positive_regulation of Sod2 1 0.00 0 0.04
133 INT231774 Gene_expression of TLR4 Positive_regulation of Gene_expression of HMOX1 1 0.30 0.68 0.04
134 INT306527 Binding of Htt and Aifm1 1 0.20 0.82 0.04
135 INT231762 TLR4 Positive_regulation of Gene_expression of HMOX1 1 0.30 0.68 0.04
136 INT220677 Binding of Mfi2 and Gtf3a 1 0.00 0.77 0.04
137 INT317161 Htt Regulation of Transcription of Bdnf 1 0.48 0.41 0.03
138 INT266903 Binding of Sod2 and Trp53 1 0.05 0 0.03
139 INT226905 Slc11a1 Regulation of Nfkb1 1 0.04 0.41 0.03
140 INT335492 CREM Positive_regulation of Transcription of HMOX1 1 0.00 0.9 0.03
141 INT199665 Binding of Fxn and Lamtor3 1 0.00 0.16 0.03
142 INT200311 Htt Positive_regulation of Rest 1 0.05 0.75 0.03
143 INT298053 Binding of Ltf and Bpifa2 1 0.01 0.58 0.03
144 INT350071 Hmox1 Regulation of Tlr4 1 0.22 0.33 0.03
145 INT341376 Sod2 Regulation of Bax 1 0.09 0.99 0.03
146 INT268199 Rab22a Regulation of Trf 1 0.11 0.17 0
147 INT229818 Fos Positive_regulation of Hmox1 1 0.43 0.37 0
148 INT350098 Gene_expression of PSEN2 Positive_regulation of Gene_expression of Hmox1 1 0.39 0 0
149 INT121179 Binding of Htt and Rest 1 0.07 0.45 0
150 INT338828 Binding of Trf and TMPRSS6 1 0.05 0.1 0
151 INT309515 Xrcc6 Regulation of Gene_expression of Htt 1 0.32 0.08 0
152 INT272441 Binding of IFNA2 and Slc11a1 1 0.02 0.97 0
153 INT121177 Binding of Bdnf and Htt 1 0.23 0.44 0
154 INT309521 PRKDC Regulation of Gene_expression of Htt 1 0.41 0.08 0
155 INT260395 Positive_regulation of Adipoq Negative_regulation of Gene_expression of Hmox1 1 0.34 1.4 0
156 INT165190 Binding of IL18 and LCN2 1 0.00 0.28 0
157 INT259670 CSE Positive_regulation of Hmox1 1 0.06 0.97 0
158 INT221113 Slc11a1 Negative_regulation of Upk1b 1 0.19 0.37 0
159 INT121180 Htt Negative_regulation of Bdnf 1 0.43 0.47 0
160 INT309519 Xrcc5 Regulation of Gene_expression of Htt 1 0.18 0.08 0
161 INT330735 GSTK1 Regulation of HMOX1 1 0.08 0.25 0
162 INT260398 Dclk2 Regulation of Gene_expression of Hmox1 1 0.01 1.02 0
163 INT226896 Slc11a1 Positive_regulation of Binding of Nfkb1 1 0.11 0.08 0
164 INT261893 Binding of Htt and Hap1 1 0.13 0.49 0
165 INT317163 Htt Regulation of Bdnf 1 0.29 0.19 0
166 INT221114 Slc11a1 Negative_regulation of Upk1a 1 0.23 0.37 0
167 INT226909 Positive_regulation of Binding of Nfkb1 and Slc11a1 1 0.07 0.18 0
168 INT306943 TF Positive_regulation of Gene_expression of Trf 1 0.01 0.9 0
169 INT309516 Htt Positive_regulation of Gene_expression of Xrcc6 1 0.49 0.06 0
170 INT121176 Htt Regulation of Bdnf 1 0.17 0.77 0
171 INT309509 Negative_regulation of Binding of Xrcc6 and Htt 1 0.31 0.41 0
172 INT226898 Binding of Nfkb1 and Slc11a1 1 0.06 0.2 0
173 INT309510 Htt Regulation of Gene_expression of Xrcc6 1 0.19 0.15 0
174 INT309508 Htt Negative_regulation of Binding of Xrcc6 1 0.31 0.48 0
175 INT268181 Binding of Trf and Erc1 1 0.02 0.07 0
176 INT353797 Binding of Ldlr and Trf 1 0.04 0.19 0
177 INT268179 Negative_regulation of Binding of Trf and Erc1 1 0.03 0.07 0
178 INT260393 Hmox1 Regulation of Positive_regulation of Bcl2 1 0.22 0.86 0
179 INT309514 Positive_regulation of Binding of Xrcc6 and Htt 1 0.33 0 0
180 INT301906 Binding of HMOX1 and HSD11B1 1 0.05 2.41 0
181 INT350068 Positive_regulation of Hmox1 Negative_regulation of Gene_expression of Ptgs2 1 0.03 0.16 0
182 INT215341 Binding of Htt and Sp1 1 0.03 0.25 0
183 INT165188 Positive_regulation of Binding of IL18 and LCN2 1 0.00 0.28 0
184 INT311011 SNRPB Positive_regulation of Gene_expression of LCN2 1 0.02 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for iron ion homeostasis. They are ordered first by their pain relevance and then by number of times they were reported in iron ion homeostasis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT73982 Gene_expression of Hmox1 141 0.78 119.43 32.17
2 INT86780 Positive_regulation of Hmox1 145 0.70 117.09 31.18
3 INT80223 Positive_regulation of Hmox1 128 0.68 77.71 17.64
4 INT76406 Gene_expression of Hmox1 140 0.78 85.86 17.15
5 INT80228 Positive_regulation of Gene_expression of Hmox1 68 0.70 62.88 14.01
6 INT116528 Gene_expression of HMOX1 106 0.78 86.13 12.8
7 INT111223 Positive_regulation of HMOX1 47 0.70 39.14 10.92
8 INT82450 Negative_regulation of Hmox1 33 0.55 19.07 8.12
9 INT124297 Gene_expression of Sod2 112 0.77 65.65 7.64
10 INT81293 Positive_regulation of Gene_expression of Hmox1 53 0.70 41.54 7.25
11 INT103824 Positive_regulation of SOD2 26 0.70 17.42 7.17
12 INT39282 Negative_regulation of SOD2 27 0.59 16.89 7.03
13 INT88245 Gene_expression of Slc11a1 42 0.53 18.86 6.2
14 INT82451 Negative_regulation of HMOX1 18 0.51 13.29 5.74
15 INT59723 Binding of Slc40a1 5 0.35 1.31 5.17
16 INT116527 Positive_regulation of Gene_expression of HMOX1 29 0.70 25.79 4.87
17 INT44066 Gene_expression of Ltf 20 0.77 15.09 4.57
18 INT12194 Gene_expression of Trf 38 0.69 18.1 4.56
19 INT64338 Negative_regulation of Hmox1 16 0.56 12.72 4.2
20 INT57525 Negative_regulation of Ltf 9 0.50 4.2 4.03
21 INT79723 Positive_regulation of Sod2 34 0.70 24.61 3.92
22 INT97096 Regulation of Hmox1 18 0.61 6.42 3.9
23 INT209018 Positive_regulation of Slc11a1 11 0.55 7.12 3.83
24 INT141658 Positive_regulation of Gene_expression of Sod2 51 0.69 35.6 3.71
25 INT142753 Gene_expression of Lcn2 28 0.76 10.03 3.62
26 INT99453 Gene_expression of SOD2 25 0.77 13.28 3.6
27 INT80224 Regulation of Hmox1 19 0.32 10.53 3.52
28 INT135773 Negative_regulation of Gene_expression of HMOX1 31 0.53 28.31 3.32
29 INT102634 Transcription of Hmox1 22 0.62 4.5 3.3
30 INT87314 Gene_expression of Htt 112 0.78 55.82 3.03
31 INT146758 Gene_expression of LCN2 45 0.78 38.29 2.97
32 INT46650 Localization of Trf 13 0.61 4.4 2.91
33 INT127904 Negative_regulation of Gene_expression of Hmox1 11 0.42 9.54 2.8
34 INT45253 Positive_regulation of Ltf 20 0.69 10.22 2.77
35 INT17033 Positive_regulation of Trf 21 0.62 11.76 2.68
36 INT151029 Positive_regulation of Gene_expression of Lcn2 8 0.68 4.04 2.65
37 INT81291 Regulation of Gene_expression of Hmox1 11 0.60 8.78 2.46
38 INT138785 Gene_expression of Lcn2 9 0.56 9.88 2.41
39 INT209019 Localization of Slc11a1 12 0.33 4.33 2.33
40 INT209027 Positive_regulation of Positive_regulation of Slc11a1 3 0.14 2.41 2.18
41 INT69080 Positive_regulation of Sfxn1 13 0.03 1.28 2.17
42 INT109334 Regulation of SOD2 13 0.60 7.48 2.14
43 INT96841 Regulation of Slc11a1 9 0.36 6.83 2.14
44 INT23748 Localization of Ltf 15 0.79 5.43 2.07
45 INT151036 Positive_regulation of Lcn2 13 0.49 8.57 2
46 INT40215 Negative_regulation of Fech 9 0.57 8.39 1.85
47 INT99742 Negative_regulation of Gene_expression of Hmox1 12 0.58 9.94 1.77
48 INT59722 Negative_regulation of Slc40a1 3 0.11 0.56 1.73
49 INT96842 Binding of Slc11a1 16 0.34 7.15 1.66
50 INT80227 Regulation of Gene_expression of Hmox1 12 0.44 11.04 1.61
51 INT283399 Binding of Lcn2 1 0.47 5.48 1.61
52 INT132882 Gene_expression of Slc40a1 4 0.17 1.35 1.6
53 INT194896 Gene_expression of Mfi2 14 0.15 6.65 1.59
54 INT138786 Positive_regulation of Lcn2 7 0.51 3.41 1.59
55 INT91232 Regulation of Positive_regulation of Hmox1 5 0.45 2.43 1.55
56 INT124299 Negative_regulation of Gene_expression of Sod2 15 0.53 13.8 1.51
57 INT178615 Binding of SOD2 12 0.48 6.93 1.51
58 INT103305 Positive_regulation of Positive_regulation of Hmox1 8 0.49 4.81 1.49
59 INT100420 Regulation of HMOX1 10 0.35 6.68 1.48
60 INT165680 Transcription of HMOX1 7 0.71 11.2 1.41
61 INT16239 Negative_regulation of Trf 9 0.32 4.06 1.35
62 INT138782 Negative_regulation of Lcn2 3 0.31 1.21 1.34
63 INT151038 Localization of Lcn2 4 0.79 1.87 1.32
64 INT127283 Regulation of Gene_expression of HMOX1 14 0.61 11.8 1.28
65 INT91320 Localization of Hmox1 8 0.81 4.06 1.28
66 INT82345 Regulation of Slc40a1 2 0.23 0.33 1.28
67 INT146755 Regulation of Lcn2 6 0.26 2.5 1.22
68 INT134061 Transcription of Sod2 5 0.68 3.46 1.19
69 INT36443 Regulation of Trf 4 0.61 1.65 1.18
70 INT115831 Transcription of Hmox1 16 0.66 5.31 1.14
71 INT138784 Positive_regulation of Gene_expression of Lcn2 3 0.49 4.44 1.13
72 INT199187 Localization of Hmox1 2 0.78 3.36 1.11
73 INT146759 Positive_regulation of LCN2 18 0.69 18.44 1.08
74 INT108997 Localization of Htt 28 0.77 3.76 1.07
75 INT116529 Binding of HMOX1 10 0.47 15.38 1.04
76 INT105445 Localization of HMOX1 5 0.71 3.11 0.98
77 INT254875 Positive_regulation of Htt 10 0.47 4.07 0.96
78 INT151035 Negative_regulation of Lcn2 5 0.42 1.99 0.96
79 INT201454 Positive_regulation of Positive_regulation of Hmox1 6 0.35 5.2 0.94
80 INT148461 Positive_regulation of Transcription of Hmox1 6 0.33 1.83 0.93
81 INT124300 Negative_regulation of Sod2 17 0.45 12.54 0.9
82 INT132883 Gene_expression of Slc11a2 5 0.75 2.96 0.89
83 INT154886 Gene_expression of Htt 18 0.76 15.51 0.82
84 INT103823 Positive_regulation of Gene_expression of SOD2 10 0.68 4.69 0.79
85 INT82568 Protein_catabolism of Hmox1 5 0.86 1.03 0.79
86 INT199649 Gene_expression of Fxn 12 0.72 20.9 0.74
87 INT146757 Positive_regulation of Gene_expression of LCN2 5 0.69 7.21 0.72
88 INT221108 Negative_regulation of Slc11a1 5 0.33 3.76 0.69
89 INT266894 Positive_regulation of Positive_regulation of Sod2 5 0.41 3.26 0.67
90 INT112173 Regulation of Transcription of SOD2 3 0.60 2.25 0.67
91 INT108857 Transcription of SOD2 5 0.70 3.51 0.66
92 INT270033 Regulation of Gene_expression of Sod2 5 0.45 2.34 0.63
93 INT287003 Negative_regulation of Positive_regulation of Hmox1 2 0.34 3.1 0.63
94 INT45252 Positive_regulation of Localization of Ltf 2 0.50 1.47 0.62
95 INT168552 Protein_catabolism of Ltf 1 0.46 0.23 0.61
96 INT98239 Negative_regulation of Htt 13 0.43 7.84 0.6
97 INT164595 Binding of LCN2 8 0.37 6.03 0.6
98 INT209023 Positive_regulation of Gene_expression of Slc11a1 3 0.22 1.19 0.6
99 INT111960 Binding of Sod2 4 0.37 2.03 0.59
100 INT158358 Positive_regulation of Steap4 1 0.48 1.55 0.59
101 INT108856 Regulation of Gene_expression of SOD2 3 0.44 0.79 0.58
102 INT287206 Regulation of Gene_expression of Htt 6 0.50 3.27 0.57
103 INT57526 Regulation of Ltf 8 0.45 2.73 0.56
104 INT215340 Localization of Htt 10 0.61 5.12 0.55
105 INT79725 Regulation of Sod2 8 0.61 4.95 0.54
106 INT209015 Positive_regulation of Localization of Slc11a1 1 0.14 0.45 0.54
107 INT197370 Gene_expression of Sfxn1 1 0.01 0.05 0.54
108 INT287204 Protein_catabolism of Htt 6 0.99 2.8 0.53
109 INT165681 Positive_regulation of Transcription of HMOX1 2 0.69 4.29 0.53
110 INT119230 Negative_regulation of Htt 5 0.42 2.99 0.5
111 INT209020 Negative_regulation of Gene_expression of Slc11a1 3 0.16 0.78 0.49
112 INT270030 Negative_regulation of Positive_regulation of Hmox1 3 0.30 2.49 0.47
113 INT220664 Positive_regulation of Gene_expression of Mfi2 2 0.10 1.23 0.47
114 INT306939 Transcription of LCN2 4 0.63 3.32 0.45
115 INT243418 Binding of Htt 14 0.30 5.94 0.44
116 INT165597 Positive_regulation of Htt 8 0.60 4.27 0.44
117 INT151030 Regulation of Gene_expression of Lcn2 1 0.41 0 0.42
118 INT168249 Localization of Lcn2 2 0.14 1.9 0.4
119 INT293210 Negative_regulation of SLC25A37 1 0.01 0 0.39
120 INT132864 Binding of Htt 15 0.46 2.34 0.38
121 INT124298 Localization of Sod2 8 0.74 3.5 0.37
122 INT157157 Negative_regulation of Localization of HMOX1 1 0.37 0.74 0.37
123 INT159542 Localization of SOD2 5 0.80 1.91 0.36
124 INT130073 Regulation of Sfxn1 2 0.42 0.14 0.36
125 INT187778 Gene_expression of Slc11a1 12 0.33 7.37 0.35
126 INT46843 Binding of Trf 10 0.47 3.45 0.35
127 INT11941 Binding of Slc11a1 3 0.14 2.18 0.35
128 INT287207 Regulation of Protein_catabolism of Htt 3 0.45 1.73 0.35
129 INT281659 Regulation of Transcription of HMOX1 2 0.27 2.12 0.33
130 INT144475 Protein_catabolism of Sod2 1 0.17 0.58 0.33
131 INT226881 Regulation of Positive_regulation of Slc11a1 1 0.09 0.95 0.32
132 INT216879 Binding of Hmox1 4 0.36 2.82 0.31
133 INT283406 Negative_regulation of Binding of Lcn2 1 0.42 0.98 0.3
134 INT135772 Regulation of Positive_regulation of HMOX1 3 0.39 1.52 0.29
135 INT130074 Positive_regulation of Positive_regulation of Sfxn1 2 0.01 0.07 0.29
136 INT254877 Positive_regulation of Gene_expression of Htt 15 0.64 6.29 0.28
137 INT173117 Binding of Ltf 4 0.12 1.85 0.28
138 INT45236 Positive_regulation of Gene_expression of Trf 3 0.62 1.67 0.28
139 INT328227 Positive_regulation of Localization of Hmox1 1 0.45 0.67 0.28
140 INT91231 Binding of Hmox1 4 0.36 0.29 0.27
141 INT319179 Positive_regulation of Positive_regulation of SOD2 1 0.68 0.51 0.27
142 INT162252 Positive_regulation of Slc40a1 4 0.36 0.79 0.25
143 INT245281 Negative_regulation of Gene_expression of Lcn2 2 0.44 1.68 0.24
144 INT109333 Negative_regulation of Gene_expression of SOD2 2 0.42 0.71 0.24
145 INT201453 Protein_catabolism of Hmox1 3 0.95 4.25 0.23
146 INT350048 Negative_regulation of Regulation of Hmox1 1 0.30 0.37 0.23
147 INT287205 Regulation of Htt 5 0.45 3.56 0.22
148 INT180525 Regulation of LCN2 4 0.54 4.37 0.18
149 INT288188 Negative_regulation of Mfi2 1 0.01 0.14 0.18
150 INT311017 Localization of LCN2 1 0.75 1.83 0.18
151 INT319182 Positive_regulation of Negative_regulation of SOD2 1 0.46 0.95 0.17
152 INT115829 Regulation of Transcription of Hmox1 1 0.35 1.03 0.17
153 INT232580 Protein_catabolism of SOD2 2 0.97 1.22 0.16
154 INT124301 Negative_regulation of Localization of Sod2 1 0.38 1.25 0.16
155 INT204148 Regulation of Gene_expression of Slc11a2 1 0.15 1.1 0.15
156 INT199642 Positive_regulation of Fxn 3 0.41 3.6 0.14
157 INT199640 Positive_regulation of Positive_regulation of Fxn 2 0.41 2.97 0.14
158 INT354092 Positive_regulation of Positive_regulation of Trf 1 0.07 0.38 0.14
159 INT311013 Negative_regulation of Gene_expression of LCN2 1 0.43 0.94 0.14
160 INT201467 Protein_catabolism of HMOX1 2 0.77 0.83 0.13
161 INT288681 Regulation of Transcription of Slc11a2 1 0.44 0.37 0.13
162 INT288683 Transcription of Slc11a2 1 0.69 0.37 0.13
163 INT311015 Regulation of Gene_expression of LCN2 1 0.54 0.83 0.13
164 INT270029 Negative_regulation of Phosphorylation of Sod2 1 0.26 1.3 0.12
165 INT288682 Binding of Slc11a2 1 0.47 0 0.12
166 INT311014 Positive_regulation of Localization of LCN2 1 0.50 1.36 0.12
167 INT270035 Phosphorylation of Sod2 1 0.50 1.29 0.12
168 INT173118 Negative_regulation of Binding of Ltf 1 0.11 0.2 0.12
169 INT283397 Positive_regulation of Binding of Lcn2 1 0.49 0.33 0.12
170 INT199652 Negative_regulation of Fxn 3 0.54 12.37 0.11
171 INT266895 Positive_regulation of Negative_regulation of Sod2 2 0.46 1.36 0.11
172 INT204146 Localization of Slc40a1 1 0.05 0.99 0.11
173 INT319178 Regulation of Negative_regulation of SOD2 1 0.27 0.53 0.11
174 INT245269 Negative_regulation of Localization of Lcn2 1 0.24 0.35 0.11
175 INT204144 Negative_regulation of Localization of Slc40a1 1 0.03 0.99 0.11
176 INT318386 Negative_regulation of Gene_expression of Slc40a1 1 0.11 0.48 0.09
177 INT3782 Regulation of Fech 1 0.00 1.05 0.09
178 INT61207 Regulation of Gene_expression of Trf 1 0.02 0.79 0.09
179 INT311016 Regulation of Binding of LCN2 1 0.39 0.35 0.09
180 INT199646 Transcription of Fxn 2 0.67 4.78 0.08
181 INT309388 Regulation of Positive_regulation of Sod2 1 0.41 0.26 0.08
182 INT164594 Binding of Lcn2 1 0.35 0.8 0.08
183 INT122944 Positive_regulation of Positive_regulation of Ltf 1 0.17 0.89 0.08
184 INT220665 Negative_regulation of Gene_expression of Mfi2 1 0.01 0.78 0.08
185 INT199643 Phosphorylation of Fxn 1 0.40 1.04 0.08
186 INT279438 Negative_regulation of Localization of Ltf 1 0.09 0.35 0.08
187 INT287203 Negative_regulation of Gene_expression of Htt 7 0.37 5.08 0.07
188 INT220660 Regulation of Mfi2 2 0.05 0.94 0.07
189 INT199655 Negative_regulation of Gene_expression of Fxn 2 0.47 3.34 0.07
190 INT146756 Regulation of Regulation of Lcn2 1 0.17 0.59 0.07
191 INT333947 Regulation of Regulation of SOD2 1 0.42 0.14 0.07
192 INT115824 Positive_regulation of Transcription of Hmox1 3 0.45 0.43 0.06
193 INT241701 Positive_regulation of Positive_regulation of Lcn2 1 0.34 2.17 0.06
194 INT261890 Positive_regulation of Gene_expression of Htt 1 0.43 0.85 0.06
195 INT150703 Positive_regulation of Gene_expression of Ltf 1 0.08 1.83 0.06
196 INT351572 Gene_expression of SFXN5 1 0.04 1.26 0.06
197 INT199654 Positive_regulation of Gene_expression of Fxn 3 0.64 2.95 0.05
198 INT341615 Binding of SLC25A37 1 0.36 0 0.05
199 INT237126 Negative_regulation of Sfxn1 1 0.01 1.32 0.05
200 INT317175 Positive_regulation of Localization of Htt 1 0.48 0 0.05
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