GO:0055086

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Name nucleobase-containing small molecule metabolic process
Categary Process
Go Slim No
Go Link GO:0055086
Unique Molecular Interactions 150
Total Molecular Interactions 199
Total Single Events 1827
Pain Genes Associated 26

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for nucleobase-containing small molecule metabolic process. They are ordered first by their pain relevance and then by number of times they were reported for nucleobase-containing small molecule metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91
2 INT73116 TYMS Negative_regulation of DNMT3B 1 0.24 0 1.6
3 INT73115 TYMS Negative_regulation of Positive_regulation of DNMT3B 1 0.24 0 1.6
4 INT111828 UPB1 Positive_regulation of Oprm1 1 0.00 0.85 1.53
5 INT253863 Binding of LBP and PNP 1 0.13 1.5 1.5
6 INT42580 CAT Negative_regulation of POMC 1 0.20 0.42 1.26
7 INT164722 Avp Regulation of NT5C 1 0.06 0.88 1.15
8 INT341897 Positive_regulation of NT5C3 Positive_regulation of Positive_regulation of Oxt 1 0.32 0.42 1.07
9 INT100283 TXN Negative_regulation of Gene_expression of POMC 1 0.54 0.5 0.85
10 INT243678 Binding of GSR and Ugcg 2 0.03 2.84 0.83
11 INT164607 Positive_regulation of GSR Positive_regulation of Gpx1 1 0.01 0.33 0.81
12 INT164606 GSR Positive_regulation of Gpx1 1 0.01 0.32 0.8
13 INT178576 CNTN2 Positive_regulation of DPYD 1 0.05 2.18 0.76
14 INT15221 RRM1 Regulation of Localization of VIP 1 0.12 0.08 0.74
15 INT15222 RRM1 Regulation of VIP 1 0.12 0.08 0.74
16 INT287132 Binding of NT5E and Comt 1 0.03 0.11 0.73
17 INT187522 ATIC Negative_regulation of Gene_expression of Nos2 1 0.02 1.46 0.7
18 INT26230 Binding of GSR and HTR1D 1 0.12 0.15 0.69
19 INT26231 Binding of GSR and HTR1B 1 0.12 0.15 0.66
20 INT164721 Binding of NT5C and Acot1 1 0.04 0.45 0.65
21 INT164723 Binding of Avp and NT5C 1 0.07 0.45 0.65
22 INT150965 NT5C2 Positive_regulation of PRKG1 1 0.04 0.07 0.62
23 INT347362 RYBP Regulation of Gene_expression of GSR 1 0.01 0 0.57
24 INT84861 Rps6ka3 Positive_regulation of Transcription of APRT 1 0.28 0.19 0.55
25 INT347369 RYBP Positive_regulation of GSR 1 0.01 0.43 0.51
26 INT210160 Binding of TNFRSF8 and TXN 1 0.47 4.16 0.48
27 INT347367 RYBP Negative_regulation of GSR 1 0.01 0.09 0.48
28 INT347364 RYBP Regulation of GSR 1 0.01 0.06 0.48
29 INT162932 TXNRD1 Negative_regulation of Phosphorylation of AKT1 1 0.14 1.01 0.47
30 INT279360 ADA Negative_regulation of Gene_expression of IFNG 1 0.06 0.51 0.44
31 INT100282 TXN Negative_regulation of Transcription of POMC 1 0.54 0.39 0.43
32 INT168435 Positive_regulation of Binding of GLRX and Gpx1 1 0.05 0.91 0.42
33 INT168434 Binding of GLRX and Gpx1 1 0.04 0.9 0.42
34 INT187519 ATIC Negative_regulation of Gene_expression of Ros1 1 0.00 1.48 0.39
35 INT13715 PDYN Positive_regulation of TYMS 1 0.27 0 0.39
36 INT187521 ATIC Positive_regulation of Prkag1 1 0.01 1.07 0.37
37 INT279369 Binding of ADA and Ifx 1 0.29 0.27 0.35
38 INT5388 PTGS1 Negative_regulation of APRT 1 0.21 0.4 0.34
39 INT83348 GSR Negative_regulation of JUND 1 0.20 0.72 0.33
40 INT83347 GSR Negative_regulation of NFKB1 1 0.25 0.72 0.33
41 INT336936 Binding of GSR and Nr3c2 1 0.06 2.29 0.31
42 INT26235 Binding of GSR and Htr1a 1 0.12 0.09 0.31
43 INT346957 HDAC9 Positive_regulation of Gene_expression of GSR 1 0.03 1.28 0.27
44 INT179233 IRF6 Negative_regulation of Binding of GSR 1 0.03 0.83 0.25
45 INT317771 GSR Positive_regulation of HDAC1 1 0.10 0.69 0.25
46 INT187518 Positive_regulation of ATIC Positive_regulation of Prkag1 1 0.01 0.99 0.25
47 INT317776 Positive_regulation of GSR Positive_regulation of HDAC1 1 0.10 0.69 0.25
48 INT100279 TXN Negative_regulation of Gene_expression of HSP90B2P 1 0.13 0.3 0.24
49 INT100280 TXN Positive_regulation of Gene_expression of MC1R 1 0.33 0.22 0.24
50 INT287131 Negative_regulation of Binding of NT5E and Comt 1 0.03 0.06 0.23
51 INT183247 ADA Negative_regulation of ADORA1 1 0.01 0 0.23
52 INT162931 TXNRD1 Negative_regulation of Phosphorylation of NQO1 1 0.13 0.5 0.23
53 INT179230 Binding of MAPK14 and GSR 1 0.03 0.5 0.23
54 INT179229 Binding of GSR and NR3C2 1 0.03 0.37 0.23
55 INT21576 NT5C3 Negative_regulation of Gene_expression of TIMP1 1 0.03 0.25 0.2
56 INT100284 TXN Positive_regulation of Gene_expression of POMC 1 0.65 0 0.19
57 INT21578 NT5C3 Regulation of Gene_expression of IL4I1 1 0.01 0.24 0.19
58 INT319173 TXN Positive_regulation of Gene_expression of SOD2 1 0.23 0.1 0.18
59 INT48595 NT5C3 Positive_regulation of CA2 1 0.01 0 0.13
60 INT48594 NT5C3 Positive_regulation of NA 1 0.00 0 0.13
61 INT287130 Positive_regulation of Binding of NT5E and Comt 1 0.04 0 0.12
62 INT146743 Positive_regulation of Binding of GSR and PLA2G4A 1 0.40 0.14 0.11
63 INT146742 Binding of GSR and PLA2G4A 1 0.28 0.14 0.11
64 INT62775 Regulation of Binding of NT5E and OPRK1 1 0.03 0 0.1
65 INT302883 Binding of TXN and Alb 1 0.06 4.13 0.1
66 INT186246 Binding of CAT and SCN5A 1 0.03 0.47 0.1
67 INT305534 Binding of HPRT1 and Tg(CAG-EGFP)D4Nagy 1 0.03 0.7 0.1
68 INT62776 Binding of NT5E and OPRK1 1 0.02 0 0.1
69 INT186245 Binding of AGRP and CAT 1 0.02 0.53 0.1
70 INT305535 Binding of HPRT1 and Runx1 1 0.41 0.7 0.1
71 INT301921 UCK2 Regulation of Gene_expression of FGF2 1 0.01 1.22 0.08
72 INT157263 PPARA Positive_regulation of APRT 1 0.54 0.92 0.08
73 INT31987 NTS Positive_regulation of Binding of GDA 1 0.50 0 0.08
74 INT157272 Adipor1 Positive_regulation of APRT 1 0.12 0.88 0.07
75 INT166919 Binding of CAT and GSTK1 1 0.09 0.16 0.07
76 INT278604 GSR Regulation of Gene_expression of SULT2A1 1 0.02 0.05 0.07
77 INT107727 ASIP Negative_regulation of RRM2 1 0.29 0.43 0.07
78 INT179232 Binding of CREM and GSR 1 0.00 0 0.06
79 INT267998 Binding of XDH and Nos1 1 0.02 0.46 0.06
80 INT210146 Binding of EGFR and TXN 1 0.15 0.09 0.06
81 INT56584 B2M Regulation of CDA 1 0.00 0.39 0.05
82 INT210155 TXN Positive_regulation of Gene_expression of TNFRSF8 1 0.49 0.22 0.05
83 INT210156 Binding of TNFSF8 and TXN 1 0.10 0.4 0.04
84 INT329226 Negative_regulation of ATIC Positive_regulation of Psmd9 1 0.01 0.58 0.04
85 INT253413 ATIC Positive_regulation of Gene_expression of Prkaa2 1 0.02 0 0.04
86 INT329229 ATIC Positive_regulation of Tpt1 1 0.01 0.58 0.04
87 INT329230 Negative_regulation of ATIC Positive_regulation of Trp53 1 0.00 0.58 0.04
88 INT155231 Positive_regulation of PPARA Positive_regulation of TXN 1 0.37 0.17 0.04
89 INT253417 ATIC Positive_regulation of Prkaa2 1 0.02 0.31 0.04
90 INT329231 ATIC Positive_regulation of Psmd9 1 0.01 0.58 0.04
91 INT329228 ATIC Positive_regulation of Trp53 1 0.01 0.58 0.04
92 INT329227 Negative_regulation of ATIC Positive_regulation of Tpt1 1 0.01 0.58 0.04
93 INT252767 CAT Regulation of Gpx1 1 0.00 0.25 0.04
94 INT187520 ATIC Positive_regulation of Phosphorylation of Prkag1 1 0.01 0 0.03
95 INT253415 ATIC Regulation of Phosphorylation of Prkaa2 1 0.03 0 0.03
96 INT253418 ATIC Regulation of Prkaa2 1 0.02 0 0.03
97 INT311144 CAT Positive_regulation of APRT 1 0.01 0 0.03
98 INT210154 TXN Regulation of Gene_expression of FASLG 1 0.09 0.23 0.03
99 INT253416 ATIC Negative_regulation of Phosphorylation of Eif4ebp1 1 0.00 0 0.03
100 INT253411 ATIC Negative_regulation of Eif4ebp1 1 0.00 0 0.03
101 INT297374 Binding of TXNRD1 and Rxra 1 0.01 0.2 0.03
102 INT253412 ATIC Negative_regulation of Rps6kb1 1 0.02 0 0.03
103 INT286268 Binding of GSR and Gpx1 2 0.02 0 0
104 INT337066 Binding of DPYD and FRA1E 1 0.19 0.8 0
105 INT197808 Binding of MEN1 and NME1 1 0.00 1.81 0
106 INT210159 Binding of PRDX1 and TXN 1 0.21 0 0
107 INT218308 Binding of HPRT1 and Grb10 1 0.26 0.07 0
108 INT98354 TXNRD1 Positive_regulation of Positive_regulation of ESR1 1 0.00 0.05 0
109 INT210163 Binding of FAS and TXN 1 0.19 0 0
110 INT285403 Binding of CAT and MPO 1 0.30 0.9 0
111 INT311145 CAT Positive_regulation of Protein_catabolism of APRT 1 0.01 0 0
112 INT36328 Binding of AMPD1 and Hmgcl 1 0.01 1.02 0
113 INT308132 Binding of RRM1 and F2 1 0.01 0 0
114 INT322607 Binding of RRM2 and TF 1 0.02 0.09 0
115 INT336713 Binding of CDA and GNPTAB 1 0.02 0.77 0
116 INT210162 TXN Negative_regulation of TNFRSF8 1 0.37 0.15 0
117 INT79644 CTNNBL1 Positive_regulation of Binding of GSR 1 0.08 0 0
118 INT79652 RIMS3 Regulation of GSR 1 0.03 0 0
119 INT294880 DPYD Positive_regulation of Ephb1 1 0.00 0.53 0
120 INT177298 Binding of GSR and GMEB1 1 0.01 0 0
121 INT210153 Regulation of Binding of TNFRSF8 and TXN 1 0.44 0.49 0
122 INT210147 Binding of TXN and TNFRSF6B 1 0.01 0 0
123 INT351623 APRT Positive_regulation of Pfkm 1 0.00 0.15 0
124 INT302882 Positive_regulation of Binding of TXN and Alb 1 0.05 1.51 0
125 INT232056 Binding of DDR1 and PNP 1 0.01 0.55 0
126 INT265023 Gsr Negative_regulation of Binding of GSR 1 0.04 0.13 0
127 INT210150 TXN Regulation of TNFRSF8 1 0.26 0.2 0
128 INT294828 DPYD Positive_regulation of PIK3CB 1 0.00 0.51 0
129 INT79645 RIMS3 Positive_regulation of Phosphorylation of GSR 1 0.04 0 0
130 INT351596 Regulation of Binding of GSR and Gpx1 1 0.02 0 0
131 INT273495 GBP4 Negative_regulation of IMPDH1 1 0.03 0.2 0
132 INT310320 GSR Negative_regulation of COQ10A 1 0.01 0.06 0
133 INT98355 TXNRD1 Negative_regulation of Positive_regulation of ESR1 1 0.00 0.09 0
134 INT330060 GSR Positive_regulation of Gene_expression of Ros1 1 0.00 0.61 0
135 INT312950 Binding of ADA and HBN1 1 0.01 0.49 0
136 INT351614 APRT Positive_regulation of MTAP 1 0.00 0.22 0
137 INT253410 ATIC Regulation of Lep 1 0.03 0.7 0
138 INT95055 Binding of CYP1A2 and TXNRD1 1 0.04 0 0
139 INT210152 Positive_regulation of Binding of TNFRSF8 and TXN 1 0.49 0.49 0
140 INT79650 CTNNBL1 Regulation of GSR 1 0.07 0 0
141 INT147144 E2F1 Positive_regulation of Transcription of TYMS 1 0.26 0 0
142 INT177266 GSR Positive_regulation of Gene_expression of CXADR 1 0.13 0 0
143 INT79647 RIMS3 Positive_regulation of Binding of GSR 1 0.04 0 0
144 INT294827 DPYD Positive_regulation of Gene_expression of REXO1 1 0.01 0.47 0
145 INT274705 Binding of TXNRD1 and Dh 1 0.00 0 0
146 INT294831 DPYD Positive_regulation of Positive_regulation of RASGRP1 1 0.00 0.53 0
147 INT210164 Binding of TXN and TXNRD1 1 0.04 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for nucleobase-containing small molecule metabolic process. They are ordered first by their pain relevance and then by number of times they were reported in nucleobase-containing small molecule metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT39507 Positive_regulation of TXNRD1 37 0.68 12.47 14.25
2 INT3845 Gene_expression of GSR 79 0.76 44.69 11.19
3 INT22132 Positive_regulation of CAT 41 0.67 18.64 10.67
4 INT11238 Positive_regulation of ADA 33 0.70 39.7 9.98
5 INT3846 Positive_regulation of GSR 60 0.50 35.16 9.37
6 INT52924 Negative_regulation of GSR 49 0.58 28.08 9.28
7 INT4228 Gene_expression of CAT 50 0.75 20.62 7.18
8 INT24800 Negative_regulation of AMPD1 44 0.59 21.19 6.76
9 INT253864 Negative_regulation of PNP 13 0.26 6.84 6.67
10 INT30206 Negative_regulation of ADA 17 0.59 10.03 5.63
11 INT35536 Negative_regulation of CAT 26 0.57 14.39 5.38
12 INT68202 Gene_expression of ADA 26 0.68 23.15 5.18
13 INT100772 Negative_regulation of TXNRD1 10 0.41 3.47 4.74
14 INT125378 Gene_expression of UPB1 4 0.59 0.25 4.49
15 INT35765 Gene_expression of TXNRD1 47 0.56 9.16 4.43
16 INT33951 Regulation of TXNRD1 18 0.51 6.97 4.02
17 INT134590 Localization of ADA 7 0.65 8.43 3.96
18 INT26233 Binding of GSR 45 0.46 18.22 3.74
19 INT62784 Gene_expression of NT5E 46 0.65 15.95 3.72
20 INT91070 Regulation of GSR 27 0.59 16.64 3.42
21 INT72798 Binding of ADA 12 0.47 7.84 3.39
22 INT174232 Gene_expression of PNP 36 0.30 8.74 3.17
23 INT83351 Positive_regulation of Gene_expression of GSR 15 0.64 12.03 2.97
24 INT131494 Regulation of ADA 8 0.52 7.37 2.97
25 INT41545 Negative_regulation of APRT 8 0.57 2.99 2.88
26 INT77339 Positive_regulation of RRM2 5 0.41 1.36 2.88
27 INT53707 Negative_regulation of RRM1 4 0.59 0.44 2.87
28 INT14902 Negative_regulation of XDH 38 0.55 24.19 2.86
29 INT57957 Localization of TXNRD1 14 0.64 4.01 2.7
30 INT145126 Positive_regulation of GLRX 5 0.12 4.55 2.53
31 INT213681 Gene_expression of TYMS 9 0.33 8.96 2.45
32 INT22129 Positive_regulation of Gene_expression of CAT 11 0.67 4.23 2.37
33 INT79658 Transcription of GSR 8 0.68 3.59 2.19
34 INT29393 Positive_regulation of APRT 18 0.67 5.28 2.13
35 INT57115 Negative_regulation of NT5E 8 0.57 4.35 2.03
36 INT69703 Gene_expression of TXN 20 0.71 3.57 2.01
37 INT110580 Regulation of Transcription of GSR 2 0.27 0.98 1.94
38 INT3496 Negative_regulation of HPRT1 7 0.58 25.05 1.92
39 INT48035 Positive_regulation of NT5C2 5 0.67 2.42 1.91
40 INT187492 Positive_regulation of ATIC 9 0.05 1.74 1.88
41 INT213676 Negative_regulation of Gene_expression of TYMS 2 0.08 1.95 1.83
42 INT174240 Negative_regulation of TYMS 12 0.57 6.35 1.82
43 INT187489 Localization of ATIC 1 0.07 4.03 1.81
44 INT48596 Positive_regulation of NT5C3 3 0.45 0.53 1.79
45 INT26416 Regulation of APRT 2 0.44 0.67 1.74
46 INT38931 Localization of APRT 3 0.78 0.87 1.7
47 INT111112 Negative_regulation of UPB1 2 0.32 0.1 1.68
48 INT88726 Gene_expression of HPRT1 36 0.78 10.12 1.58
49 INT3892 Positive_regulation of XDH 8 0.67 8.57 1.5
50 INT100286 Localization of TXN 21 0.73 5.13 1.48
51 INT181873 Regulation of Localization of ADA 1 0.07 1.98 1.41
52 INT164720 Positive_regulation of Localization of NT5C 1 0.06 0.87 1.39
53 INT96420 Positive_regulation of NT5E 9 0.49 3.7 1.38
54 INT155036 Localization of NT5E 6 0.73 4.1 1.35
55 INT110569 Gene_expression of XDH 31 0.75 18.35 1.34
56 INT70615 Binding of TXNRD1 25 0.36 12.15 1.27
57 INT187494 Gene_expression of ATIC 6 0.06 5.45 1.27
58 INT106261 Negative_regulation of DPYD 16 0.59 15.02 1.19
59 INT110582 Localization of GSR 10 0.79 4.03 1.19
60 INT91122 Localization of CAT 6 0.78 4.13 1.19
61 INT88568 Positive_regulation of RRM1 4 0.41 1.81 1.14
62 INT192073 Positive_regulation of Gene_expression of ADA 8 0.47 10.35 1.12
63 INT94690 Gene_expression of DPYD 12 0.75 4.6 1.07
64 INT281849 Binding of RRM2 5 0.17 0.43 1.07
65 INT341885 Positive_regulation of Localization of NT5C3 1 0.49 0.41 1.07
66 INT231528 Localization of NT5C3 2 0.73 1.78 1.06
67 INT164416 Gene_expression of CDA 8 0.64 5.17 1.02
68 INT53682 Regulation of Gene_expression of CAT 2 0.60 0.36 0.96
69 INT44122 Positive_regulation of AMPD1 4 0.44 1.88 0.92
70 INT66314 Negative_regulation of Positive_regulation of CAT 4 0.42 0.8 0.91
71 INT1189 Gene_expression of AMPD1 7 0.59 4.1 0.9
72 INT165982 Regulation of UPB1 1 0.33 0.08 0.9
73 INT69705 Positive_regulation of TXN 8 0.63 2.35 0.89
74 INT58405 Gene_expression of GDA 3 0.75 0.24 0.86
75 INT132912 Phosphorylation of APRT 2 0.61 0.63 0.84
76 INT110859 Negative_regulation of Positive_regulation of TXNRD1 1 0.41 0.65 0.82
77 INT210193 Binding of TXN 31 0.44 6.88 0.78
78 INT239499 Positive_regulation of Positive_regulation of ATIC 1 0.05 0.53 0.77
79 INT287128 Protein_catabolism of NT5E 2 0.11 0.64 0.76
80 INT279366 Positive_regulation of Localization of ADA 2 0.42 4.37 0.76
81 INT132914 Positive_regulation of Phosphorylation of APRT 1 0.45 0 0.75
82 INT57008 Positive_regulation of HPRT1 11 0.50 2.81 0.74
83 INT178587 Positive_regulation of DPYD 4 0.50 4.7 0.74
84 INT115293 Regulation of Gene_expression of TXN 2 0.19 0.78 0.73
85 INT294133 Regulation of Gene_expression of NT5E 4 0.12 1.36 0.71
86 INT170772 Negative_regulation of Gene_expression of GSR 8 0.41 3.05 0.7
87 INT110581 Positive_regulation of Localization of GSR 1 0.68 0.33 0.7
88 INT164717 Localization of NT5C 1 0.09 0.43 0.69
89 INT150966 Positive_regulation of Positive_regulation of NT5C2 1 0.49 0.07 0.63
90 INT164718 Regulation of NT5C 3 0.19 1.36 0.62
91 INT210028 Protein_catabolism of ADA 1 0.07 0.13 0.62
92 INT107417 Regulation of CAT 8 0.60 2.4 0.61
93 INT155035 Binding of NT5E 3 0.36 1.78 0.61
94 INT42882 Positive_regulation of GDA 2 0.45 1.26 0.58
95 INT164719 Regulation of Regulation of NT5C 1 0.03 0.44 0.58
96 INT32062 Regulation of Negative_regulation of AMPD1 1 0.14 0.5 0.58
97 INT106382 Gene_expression of NME1 13 0.66 5.18 0.56
98 INT179248 Positive_regulation of Positive_regulation of GSR 3 0.40 4.65 0.56
99 INT130387 Binding of CAT 4 0.36 2.39 0.55
100 INT84859 Transcription of APRT 1 0.69 0.19 0.55
101 INT58188 Localization of CDA 1 0.62 0.09 0.55
102 INT84860 Negative_regulation of Transcription of APRT 1 0.42 0.19 0.55
103 INT200072 Gene_expression of APRT 8 0.65 1 0.54
104 INT179373 Localization of XDH 3 0.20 1.97 0.54
105 INT119483 Negative_regulation of Gene_expression of AMPD1 2 0.04 1.95 0.5
106 INT187491 Phosphorylation of ATIC 6 0.07 1.67 0.49
107 INT13717 Positive_regulation of TYMS 3 0.40 1.64 0.49
108 INT83349 Negative_regulation of Binding of GSR 3 0.39 1.48 0.49
109 INT77338 Negative_regulation of RRM2 2 0.38 0 0.49
110 INT168045 Negative_regulation of ATIC 3 0.10 1.2 0.48
111 INT107683 Positive_regulation of Negative_regulation of NME1 1 0.49 0.93 0.48
112 INT107684 Phosphorylation of NME1 1 0.61 0.92 0.48
113 INT107687 Negative_regulation of NME1 1 0.57 0.91 0.48
114 INT155236 Negative_regulation of TXN 5 0.53 0.66 0.46
115 INT251661 Phosphorylation of NT5E 2 0.21 1.59 0.46
116 INT351236 Negative_regulation of Negative_regulation of TXNRD1 1 0.22 0.06 0.44
117 INT143683 Negative_regulation of Gene_expression of ADA 1 0.09 0.28 0.44
118 INT301932 Negative_regulation of UCK2 1 0.03 5.03 0.43
119 INT210194 Positive_regulation of Gene_expression of TXN 1 0.46 1.17 0.43
120 INT100287 Regulation of TXN 2 0.41 0.62 0.42
121 INT178586 Localization of DPYD 1 0.36 0.76 0.42
122 INT96419 Positive_regulation of Gene_expression of NT5E 3 0.49 1.46 0.41
123 INT94691 Binding of DPYD 2 0.47 0 0.39
124 INT201844 Transcription of GDA 1 0.05 1.2 0.38
125 INT201848 Negative_regulation of GDA 1 0.06 1.21 0.38
126 INT201849 Negative_regulation of Transcription of GDA 1 0.04 1.21 0.38
127 INT84981 Negative_regulation of Gene_expression of CAT 3 0.41 0.35 0.35
128 INT126817 Phosphorylation of GDA 1 0.79 0 0.35
129 INT20856 Binding of APRT 2 0.36 0 0.34
130 INT168433 Regulation of GLRX 1 0.05 0.66 0.34
131 INT25725 Positive_regulation of NME1 1 0.01 0.25 0.34
132 INT258059 Negative_regulation of Positive_regulation of GSR 3 0.41 1.79 0.33
133 INT286267 Positive_regulation of Negative_regulation of GSR 1 0.12 0.9 0.33
134 INT279365 Regulation of Regulation of ADA 1 0.23 0 0.33
135 INT287129 Regulation of NT5E 3 0.12 1.02 0.32
136 INT261239 Binding of XDH 10 0.34 3.16 0.31
137 INT83354 Positive_regulation of Binding of GSR 2 0.43 0.69 0.31
138 INT271882 Protein_catabolism of TXN 1 0.09 0.17 0.31
139 INT183814 Transcription of HPRT1 6 0.69 1.04 0.29
140 INT301935 Gene_expression of UCK2 5 0.13 4.4 0.27
141 INT129470 Regulation of RRM2 4 0.22 0.36 0.27
142 INT274774 Regulation of RRM1 2 0.16 0.07 0.27
143 INT354743 Gene_expression of NT5C 1 0.20 1.72 0.25
144 INT98363 Positive_regulation of Gene_expression of TXNRD1 8 0.35 0.29 0.24
145 INT88725 Regulation of HPRT1 5 0.62 1.28 0.24
146 INT308129 Positive_regulation of Positive_regulation of RRM1 2 0.04 0.82 0.24
147 INT184652 Binding of RRM1 5 0.22 0.55 0.23
148 INT237464 Positive_regulation of Negative_regulation of TYMS 2 0.20 0.53 0.23
149 INT88721 Positive_regulation of Gene_expression of HPRT1 7 0.49 2.16 0.21
150 INT294138 Positive_regulation of Localization of NT5E 1 0.14 0.41 0.21
151 INT294141 Regulation of Localization of NT5E 1 0.12 0.42 0.21
152 INT210191 Positive_regulation of Positive_regulation of TXN 1 0.46 1.16 0.21
153 INT185899 Phosphorylation of HPRT1 1 0.68 0.66 0.21
154 INT311146 Protein_catabolism of APRT 1 0.01 0.39 0.2
155 INT44173 Regulation of GDA 1 0.44 0 0.19
156 INT301934 Regulation of UCK2 1 0.02 1.74 0.19
157 INT21580 Negative_regulation of NT5C3 1 0.04 0.23 0.19
158 INT179250 Negative_regulation of Transcription of GSR 2 0.56 1.7 0.18
159 INT179247 Negative_regulation of Localization of GSR 1 0.24 0.65 0.18
160 INT58908 Positive_regulation of Negative_regulation of AMPD1 2 0.44 0.86 0.17
161 INT184651 Gene_expression of RRM1 6 0.48 3.46 0.15
162 INT284968 Positive_regulation of CDA 2 0.05 0.34 0.15
163 INT267995 Negative_regulation of Negative_regulation of XDH 2 0.30 0.77 0.15
164 INT223026 Regulation of XDH 2 0.32 2.38 0.15
165 INT274773 Gene_expression of RRM2 1 0.08 0.21 0.15
166 INT7632 Protein_catabolism of AMPD1 1 0.70 0.56 0.15
167 INT310770 Positive_regulation of Transcription of HPRT1 1 0.49 0.48 0.14
168 INT184649 Localization of RRM1 3 0.07 1.08 0.13
169 INT279806 Regulation of TYMS 2 0.05 1 0.12
170 INT330011 Positive_regulation of Gene_expression of APRT 1 0.02 0 0.12
171 INT181919 Protein_catabolism of CAT 1 0.15 0.54 0.12
172 INT197840 Binding of NME1 2 0.04 1.14 0.11
173 INT258071 Positive_regulation of Negative_regulation of APRT 1 0.02 1.19 0.11
174 INT144156 Negative_regulation of Localization of TXNRD1 1 0.47 0 0.11
175 INT187490 Regulation of ATIC 1 0.04 0 0.11
176 INT263205 Negative_regulation of Gene_expression of XDH 2 0.41 0.63 0.1
177 INT320095 Negative_regulation of Binding of XDH 1 0.16 0.46 0.1
178 INT323226 Negative_regulation of Localization of ADA 1 0.35 3.05 0.1
179 INT315821 Regulation of Transcription of RRM1 1 0.21 0.67 0.1
180 INT284953 Protein_catabolism of CDA 1 0.07 1.18 0.1
181 INT110170 Positive_regulation of Positive_regulation of ADA 1 0.49 0.46 0.1
182 INT110568 Positive_regulation of Gene_expression of XDH 7 0.49 5.14 0.09
183 INT266463 Positive_regulation of Positive_regulation of CAT 2 0.49 1.85 0.09
184 INT315817 Transcription of RRM1 2 0.42 0.67 0.09
185 INT88724 Regulation of Gene_expression of HPRT1 2 0.27 1.04 0.09
186 INT23647 Negative_regulation of CDA 3 0.38 1.48 0.08
187 INT301933 Binding of UCK2 1 0.02 2.58 0.08
188 INT187493 Binding of ATIC 1 0.04 0.07 0.08
189 INT31988 Binding of GDA 1 0.36 0 0.08
190 INT354744 Binding of NT5C 1 0.10 0.29 0.08
191 INT212593 Negative_regulation of IMPDH1 4 0.10 3.01 0.07
192 INT264609 Regulation of Gene_expression of GSR 3 0.43 2.44 0.07
193 INT276800 Transcription of TXNRD1 2 0.19 0.36 0.07
194 INT212587 Phosphorylation of IMPDH1 1 0.06 0.87 0.07
195 INT184647 Regulation of Localization of RRM1 1 0.04 0.07 0.07
196 INT267994 Positive_regulation of Negative_regulation of XDH 1 0.33 0.37 0.07
197 INT16298 Binding of AMPD1 1 0.04 0.45 0.07
198 INT212597 Positive_regulation of Phosphorylation of IMPDH1 1 0.04 0.87 0.07
199 INT273506 Gene_expression of IMPDH1 5 0.18 0.45 0.06
200 INT242044 Protein_catabolism of GSR 3 0.88 0.05 0.06
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