GO:0055089

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Name fatty acid homeostasis
Categary Process
Go Slim No
Go Link GO:0055089
Unique Molecular Interactions 351
Total Molecular Interactions 470
Total Single Events 7419
Pain Genes Associated 11

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for fatty acid homeostasis. They are ordered first by their pain relevance and then by number of times they were reported for fatty acid homeostasis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87
2 INT288731 Binding of Got1 and Gpt 1 0.23 1.25 1.61
3 INT41100 Mdk Positive_regulation of Localization of INS 1 0.01 0 1.55
4 INT340300 Ea1 Positive_regulation of Gene_expression of Sirt1 1 0.08 1.68 1.49
5 INT131462 NGF Regulation of Localization of INS 1 0.40 0.97 1.2
6 INT40424 CCK Regulation of Localization of INS 1 0.02 0 0.97
7 INT75283 SST Negative_regulation of Localization of INS 2 0.47 1.45 0.96
8 INT109103 MMP2 Positive_regulation of INS 1 0.33 1.07 0.89
9 INT340294 Ea1 Positive_regulation of Sirt1 1 0.06 0.53 0.83
10 INT131463 NTRK1 Regulation of Localization of INS 1 0.41 0.63 0.8
11 INT181616 INS Positive_regulation of IRS1 1 0.01 1 0.79
12 INT63588 Aap Positive_regulation of Positive_regulation of Got1 1 0.31 0.6 0.79
13 INT316544 BCL2L11 Regulation of INS 1 0.00 1.36 0.77
14 INT19577 Gabrg1 Negative_regulation of Got1 1 0.04 0.16 0.74
15 INT63589 Binding of Got1 and Gpt 1 0.36 0.56 0.74
16 INT75937 MLXIPL Regulation of Csf2 1 0.01 0.68 0.74
17 INT41165 Gtf3a Regulation of INS 1 0.00 0.15 0.74
18 INT41164 Binding of INS and SST 1 0.07 0.14 0.73
19 INT31643 POMC Regulation of INS 1 0.59 0.62 0.73
20 INT242883 INS Negative_regulation of Gene_expression of TLR2 1 0.17 2.35 0.6
21 INT29847 INS Regulation of Localization of AVP 1 0.23 0.24 0.59
22 INT291262 Positive_regulation of INS Positive_regulation of Mapk1 1 0.03 1.78 0.58
23 INT291258 INS Positive_regulation of Mapk1 1 0.04 1.77 0.58
24 INT103165 NGF Positive_regulation of Localization of INS 1 0.05 0 0.58
25 INT29252 Regulation of INS Positive_regulation of GH1 1 0.26 0.08 0.54
26 INT29253 INS Positive_regulation of GH1 1 0.44 0.08 0.53
27 INT311767 INS Negative_regulation of Gene_expression of SLC1A3 1 0.52 0 0.52
28 INT288729 Positive_regulation of Binding of Got1 and Gpt 1 0.25 0.61 0.49
29 INT101001 GHRH Regulation of Localization of INS 1 0.28 0 0.47
30 INT340296 Ea1 Regulation of Gene_expression of Sirt1 1 0.08 0.15 0.46
31 INT240618 Binding of INS and ADIPOQ 3 0.17 2.54 0.4
32 INT285725 Binding of IGF1R and INS 1 0.27 0.07 0.4
33 INT29052 Binding of INS and INSRR 1 0.02 0.23 0.4
34 INT29053 Regulation of Binding of INS and INSRR 1 0.01 0.24 0.4
35 INT78621 PRL Positive_regulation of Localization of INS 2 0.06 0.5 0.39
36 INT291256 INS Negative_regulation of Positive_regulation of Mdk 1 0.01 1.65 0.39
37 INT113040 IHH Regulation of Gene_expression of INS 1 0.12 0.37 0.37
38 INT89386 INS Positive_regulation of Phosphorylation of AKT1 3 0.43 1.48 0.36
39 INT4382 RIPK2 Regulation of INS 1 0.12 0.58 0.36
40 INT183786 IL6 Negative_regulation of INS 1 0.09 1.61 0.35
41 INT183784 INS Negative_regulation of Binding of TBK1 1 0.01 1.81 0.34
42 INT183783 INS Negative_regulation of TBK1 1 0.01 1.81 0.34
43 INT183793 INS Negative_regulation of Binding of Ros1 1 0.16 1.66 0.34
44 INT183785 INS Positive_regulation of Gene_expression of NFKBIB 1 0.03 1.83 0.34
45 INT183780 INS Negative_regulation of Gene_expression of CYBB 1 0.02 1.74 0.34
46 INT4381 RIPK2 Positive_regulation of Localization of INS 1 0.13 0.53 0.34
47 INT183782 INS Negative_regulation of Gene_expression of TBK1 1 0.01 1.81 0.34
48 INT89381 INS Positive_regulation of AKT1 6 0.43 3.06 0.33
49 INT190683 Binding of A2M and INS 4 0.11 4.97 0.32
50 INT238895 Binding of CRP and INS 1 0.00 0.93 0.32
51 INT191240 SAE1 Regulation of Localization of INS 1 0.08 1.15 0.3
52 INT51275 IGF1 Negative_regulation of INS 2 0.35 0.98 0.29
53 INT291202 Positive_regulation of INS Positive_regulation of AKT1 1 0.01 0.76 0.29
54 INT71550 GTPBP4 Regulation of Localization of INS 1 0.00 0.16 0.28
55 INT291201 Regulation of INS Positive_regulation of GOPC 1 0.00 0.35 0.28
56 INT291200 INS Positive_regulation of GOPC 1 0.01 0.3 0.28
57 INT242878 INS Negative_regulation of Gene_expression of SPI1 1 0.04 1.81 0.27
58 INT224406 INS Regulation of Localization of PYY 1 0.11 0.27 0.27
59 INT224405 INS Regulation of Localization of CCK 1 0.12 0.27 0.27
60 INT91449 Gpt Positive_regulation of Got1 1 0.01 3.26 0.26
61 INT74433 Binding of INS and Cpe 2 0.03 0 0.25
62 INT291261 INS Positive_regulation of Phosphorylation of Mdk 1 0.01 0.28 0.25
63 INT309888 INS Positive_regulation of Gene_expression of FAAH 1 0.04 1.19 0.25
64 INT308815 Got1 Positive_regulation of Ldha 1 0.09 0.71 0.24
65 INT308818 Got1 Positive_regulation of Tnf 1 0.08 0.71 0.24
66 INT242875 INS Negative_regulation of Gene_expression of TLR4 1 0.11 1.41 0.24
67 INT334390 ADIPOQ Positive_regulation of Localization of INS 1 0.09 1.3 0.23
68 INT87750 IGFBP3 Negative_regulation of INS 1 0.11 0.86 0.23
69 INT63196 INS Positive_regulation of IL2 1 0.10 0.3 0.23
70 INT63203 INS Positive_regulation of ESR1 1 0.09 0.3 0.23
71 INT63195 INS Positive_regulation of CD8A 1 0.19 0.3 0.23
72 INT63199 INS Positive_regulation of PGR 1 0.11 0.3 0.23
73 INT328382 Positive_regulation of Ghrl Positive_regulation of Localization of INS 1 0.03 1.08 0.23
74 INT108808 Binding of IAPP and INS 1 0.32 1.36 0.23
75 INT288732 Got1 Positive_regulation of Gene_expression of Gpt 1 0.31 0.52 0.23
76 INT207845 Binding of INS and Hypism 3 0.04 2.88 0.22
77 INT255044 GLP1R Positive_regulation of Localization of INS 3 0.49 1.47 0.22
78 INT214481 ROS1 Negative_regulation of Gene_expression of INS 1 0.00 0.37 0.22
79 INT39263 POMC Negative_regulation of INS 1 0.23 0.6 0.22
80 INT257397 Binding of FGD1 and INS 1 0.07 0.27 0.21
81 INT355103 Binding of Ins2 and Ins1 1 0.12 2 0.21
82 INT74437 Negative_regulation of Cpe Positive_regulation of Localization of INS 1 0.06 0 0.2
83 INT78622 POMC Positive_regulation of Localization of INS 1 0.07 0 0.2
84 INT3592 INS Positive_regulation of AVP 1 0.05 0.28 0.2
85 INT339901 Binding of INS and SCN5A 1 0.01 0.18 0.2
86 INT3591 Negative_regulation of INS Positive_regulation of AVP 1 0.04 0.28 0.2
87 INT74439 Negative_regulation of Cpe Positive_regulation of INS 1 0.06 0 0.2
88 INT217661 LEP Positive_regulation of INS 2 0.25 1.85 0.19
89 INT217665 ADIPOQ Positive_regulation of INS 2 0.06 1.8 0.19
90 INT110717 CGA Positive_regulation of Localization of INS 1 0.03 0.5 0.19
91 INT32395 POMC Positive_regulation of INS 1 0.41 0.52 0.19
92 INT190628 Negative_regulation of Binding of Rab7 and Sirt1 1 0.33 0.62 0.17
93 INT190638 Binding of Rab7 and Sirt1 1 0.29 0.62 0.17
94 INT15523 INS Negative_regulation of FFAR1 1 0.02 0.35 0.16
95 INT206059 IL6 Positive_regulation of INS 1 0.02 1.16 0.16
96 INT311227 INS Negative_regulation of HBA1 1 0.01 0.52 0.16
97 INT71548 ADRA2C Negative_regulation of Localization of INS 1 0.04 0.13 0.16
98 INT240620 Binding of INS and SHBG 4 0.12 3.35 0.15
99 INT207253 INS Negative_regulation of TXNIP 1 0.45 1.2 0.15
100 INT289525 Sirt1 Negative_regulation of Negative_regulation of Ucp2 1 0.32 0.86 0.15
101 INT194136 Binding of HLA-E and INS 1 0.01 0.95 0.15
102 INT31641 POMC Regulation of Gene_expression of INS 1 0.26 0.25 0.15
103 INT157275 Binding of PRKAA1 and Adipoq 1 0.01 1.13 0.15
104 INT217667 LEP Negative_regulation of Localization of INS 1 0.15 1.18 0.14
105 INT141001 Negative_regulation of CPOX Regulation of Localization of INS 1 0.17 0.07 0.14
106 INT217664 LEP Negative_regulation of INS 1 0.15 1.18 0.14
107 INT157273 Adipoq Positive_regulation of PRKAA1 1 0.03 1.16 0.14
108 INT321408 INS Positive_regulation of EGR1 1 0.03 2.36 0.13
109 INT117371 SUCLA2 Positive_regulation of Localization of INS 1 0.03 0 0.13
110 INT117372 SUCLA2 Regulation of Localization of INS 1 0.02 0 0.13
111 INT321414 INS Positive_regulation of Transcription of EGR1 1 0.03 2.36 0.13
112 INT3751 Binding of GOT1 and PIK3C2A 1 0.08 0.68 0.12
113 INT255710 Binding of INS and LOC691138 1 0.00 0.51 0.12
114 INT3752 Binding of GOT1 and LDHA 1 0.11 0.68 0.12
115 INT352501 PRKAB1 Positive_regulation of INS 1 0.04 1.36 0.12
116 INT270746 INS Regulation of LEP 1 0.07 0.72 0.11
117 INT164923 INS Positive_regulation of GIP 1 0.43 0.18 0.11
118 INT267124 IGF1 Negative_regulation of Gene_expression of INS 2 0.14 0.18 0.1
119 INT26176 POMC Negative_regulation of Localization of INS 1 0.36 0.06 0.1
120 INT352500 Binding of FAT1 and INS 1 0.01 1.38 0.1
121 INT102248 INS Positive_regulation of Binding of HIF1A 1 0.13 0.96 0.1
122 INT350820 INS Regulation of SELS 1 0.13 1.11 0.1
123 INT27844 Binding of INS and Gh 1 0.03 0.1 0.1
124 INT262996 ADIPOQ Regulation of INS 1 0.13 1.25 0.1
125 INT102246 Binding of HIF1A and INS 1 0.07 0.96 0.1
126 INT27841 Binding of INS and GAL 1 0.04 0.1 0.1
127 INT267684 Binding of INS and ARID1B 3 0.10 6.08 0.09
128 INT164925 GIP Positive_regulation of Localization of INS 2 0.59 0.86 0.09
129 INT341235 Negative_regulation of INS Positive_regulation of Phosphorylation of Eif4ebp1 1 0.01 0.24 0.09
130 INT114414 TF Regulation of INS 1 0.18 0.09 0.09
131 INT109959 INS Positive_regulation of FBF1 1 0.27 0.24 0.09
132 INT289539 Negative_regulation of Sirt1 Negative_regulation of Gene_expression of Agrp 1 0.29 0.47 0.09
133 INT251469 INS Negative_regulation of Gene_expression of SHBG 2 0.11 4.11 0.08
134 INT173130 Binding of INS and PPARA 2 0.04 1.8 0.08
135 INT246625 Sirt1 Positive_regulation of Negative_regulation of Trp53 1 0.10 0.96 0.08
136 INT172836 Binding of INS and T2dm2 1 0.00 1.65 0.08
137 INT289536 Sirt1 Negative_regulation of Localization of Pparg 1 0.13 0.43 0.08
138 INT157264 PPARA Positive_regulation of PRKAA1 1 0.03 0.92 0.08
139 INT157271 Adipor1 Positive_regulation of PRKAA1 1 0.01 0.89 0.08
140 INT291040 Binding of CFH and INS 1 0.25 1.32 0.08
141 INT289603 Sirt1 Negative_regulation of Localization of PPARG 1 0.02 0.43 0.08
142 INT289540 Sirt1 Negative_regulation of Localization of Ins1 1 0.03 0.43 0.08
143 INT279417 Binding of PPARA and MLXIPL 3 0.00 0.33 0.07
144 INT352517 Binding of INS and Adipoq 1 0.09 1.32 0.07
145 INT289533 Sirt1 Negative_regulation of Pparg 1 0.18 0.42 0.07
146 INT328306 GH1 Positive_regulation of Localization of INS 1 0.01 0.12 0.07
147 INT58648 Binding of HSD11B1 and INS 1 0.04 1.65 0.07
148 INT256160 Positive_regulation of Binding of Pgc and Sirt1 1 0.55 0.21 0.07
149 INT207824 KCNJ5 Regulation of Localization of INS 1 0.01 0 0.07
150 INT279421 Binding of NR1H4 and MLXIPL 1 0.00 0.27 0.07
151 INT289602 Sirt1 Negative_regulation of PPARG 1 0.02 0.37 0.07
152 INT279413 Binding of RARB and MLXIPL 1 0.00 0.27 0.07
153 INT256161 Binding of Pgc and Sirt1 1 0.38 0.21 0.07
154 INT58649 Binding of INS and Serpine1 1 0.01 1.64 0.07
155 INT207552 Binding of GH1 and INS 1 0.23 0.55 0.07
156 INT311225 GLP1R Positive_regulation of Gene_expression of INS 1 0.49 0.33 0.06
157 INT202244 Igfbp1 Regulation of Localization of INS 1 0.06 0 0.06
158 INT253377 Lep Negative_regulation of Phosphorylation of Prkaa2 1 0.24 1.24 0.06
159 INT328305 GHS Positive_regulation of Localization of INS 1 0.02 0.07 0.05
160 INT218614 INS Positive_regulation of Binding of IGF1 1 0.39 0.79 0.05
161 INT298733 INS Regulation of ACSBG1 1 0.00 0.97 0.05
162 INT328387 INS Negative_regulation of Gene_expression of Ghrl 1 0.01 0.6 0.05
163 INT328371 Ghrl Negative_regulation of INS 1 0.03 0.13 0.05
164 INT258084 Binding of IL6 and Regulation of Gene_expression of INS 1 0.11 0.62 0.05
165 INT280057 Zglp1 Positive_regulation of Transcription of INS 1 0.04 0.52 0.05
166 INT217666 ADIPOQ Regulation of Gene_expression of INS 1 0.03 1.99 0.05
167 INT218616 Binding of IGFBP3 and INS 1 0.07 0.68 0.05
168 INT340293 Binding of Ins1 and Sirt1 1 0.25 1.25 0.05
169 INT112644 INS Negative_regulation of OVGP1 1 0.43 0 0.05
170 INT89384 Negative_regulation of INS Positive_regulation of AKT1 2 0.36 1.37 0.04
171 INT213263 INS Positive_regulation of EDN1 1 0.12 0.54 0.04
172 INT207846 Hypism Regulation of INS 1 0.06 1.14 0.04
173 INT350015 ARID1B Regulation of Localization of INS 1 0.03 2.6 0.04
174 INT253413 ATIC Positive_regulation of Gene_expression of Prkaa2 1 0.02 0 0.04
175 INT341231 INS Positive_regulation of Phosphorylation of Eif4ebp1 1 0.01 0.13 0.04
176 INT314622 Binding of INS and Ex 1 0.08 0.44 0.04
177 INT267155 Binding of INS and SUGT1 1 0.02 0.81 0.04
178 INT253417 ATIC Positive_regulation of Prkaa2 1 0.02 0.31 0.04
179 INT350121 INS Negative_regulation of Positive_regulation of SHBG 1 0.09 1.48 0.04
180 INT199212 Binding of IGFBP1 and INS 1 0.05 1.77 0.04
181 INT253363 Lep Regulation of Prkaa2 1 0.15 0.08 0.04
182 INT289541 Sirt1 Regulation of Gene_expression of Agrp 1 0.41 0.52 0.04
183 INT350118 INS Negative_regulation of SHBG 1 0.09 1.42 0.04
184 INT253365 Il6 Negative_regulation of Prkaa2 1 0.23 0 0.04
185 INT228591 Adipoq Positive_regulation of Phosphorylation of Prkaa2 1 0.31 0.61 0.04
186 INT289538 Sirt1 Positive_regulation of Stat3 1 0.34 0.37 0.04
187 INT89385 INS Positive_regulation of Phosphorylation of PTK2B 1 0.15 0.59 0.04
188 INT202231 Binding of IGF1 and INS 2 0.28 1.38 0.03
189 INT352519 INS Positive_regulation of Localization of Slc2a4 1 0.07 0.97 0.03
190 INT207554 GH1 Negative_regulation of Phosphorylation of INS 1 0.26 0.28 0.03
191 INT230854 INS Regulation of Positive_regulation of SNAP47 1 0.09 1.03 0.03
192 INT253415 ATIC Regulation of Phosphorylation of Prkaa2 1 0.03 0 0.03
193 INT230851 INS Regulation of VCAM1 1 0.07 1.02 0.03
194 INT253418 ATIC Regulation of Prkaa2 1 0.02 0 0.03
195 INT230423 INS Negative_regulation of Lipg 1 0.03 0.74 0.03
196 INT289542 Sirt1 Negative_regulation of Stat3 1 0.32 0.31 0.03
197 INT289526 Binding of Arc and Sirt1 1 0.08 0.55 0.03
198 INT181618 NOS3 Positive_regulation of INS 1 0.02 0.59 0.03
199 INT289599 Sirt1 Positive_regulation of Ppargc1a 1 0.51 0.36 0.03
200 INT285726 Binding of ALB and INS 1 0.22 0.61 0.03

Single Events

The table below shows the top 100 pain related interactions that have been reported for fatty acid homeostasis. They are ordered first by their pain relevance and then by number of times they were reported in fatty acid homeostasis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT812 Localization of INS 1026 0.81 515.6 145.31
2 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01
3 INT251 Regulation of INS 398 0.62 232.47 55.04
4 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43
5 INT2604 Positive_regulation of Got1 223 0.70 154.78 49.51
6 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98
7 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52
8 INT3253 Negative_regulation of Localization of INS 205 0.59 130.39 36.61
9 INT2274 Regulation of Localization of INS 101 0.62 41.55 34.79
10 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38
11 INT3206 Positive_regulation of Got1 39 0.69 19.36 17.02
12 INT2480 Negative_regulation of Got1 43 0.51 14.47 16.09
13 INT14572 Binding of INS 205 0.48 175.43 13.38
14 INT8210 Positive_regulation of Gene_expression of INS 188 0.68 146.57 12.83
15 INT4605 Negative_regulation of Gene_expression of INS 220 0.58 139.66 10.75
16 INT3851 Gene_expression of Got1 58 0.65 29.15 10.52
17 INT4606 Regulation of Gene_expression of INS 67 0.61 54.69 7.53
18 INT4208 Regulation of Got1 23 0.44 6.72 6.62
19 INT17779 Negative_regulation of Got1 12 0.40 3.5 6.08
20 INT4613 Positive_regulation of Sirt1 32 0.67 18.19 5.53
21 INT27415 Negative_regulation of Positive_regulation of Got1 15 0.51 10.99 5.14
22 INT240934 Gene_expression of Sirt1 24 0.75 18.77 4.68
23 INT89394 Phosphorylation of INS 37 0.82 35.84 3.9
24 INT3919 Localization of Got1 10 0.71 2.95 3.28
25 INT31340 Positive_regulation of Gene_expression of Got1 20 0.46 10.5 3.17
26 INT7909 Positive_regulation of Positive_regulation of Got1 8 0.49 6.44 3.06
27 INT38987 Protein_catabolism of INS 21 0.99 11.92 2.91
28 INT32623 Negative_regulation of Regulation of INS 16 0.43 10.96 2.9
29 INT45971 Negative_regulation of GOT1 9 0.51 6.2 2.84
30 INT4419 Gene_expression of GOT1 20 0.65 22.53 2.53
31 INT3315 Negative_regulation of Positive_regulation of INS 31 0.57 14.73 2.27
32 INT26177 Regulation of Regulation of INS 19 0.44 11.32 2.18
33 INT38095 Negative_regulation of Positive_regulation of Got1 3 0.20 1.97 2.16
34 INT63598 Localization of Got1 2 0.70 0.87 2.11
35 INT221409 Regulation of Sirt1 8 0.58 5.53 2.1
36 INT17274 Gene_expression of Got1 11 0.58 3.98 2
37 INT3866 Positive_regulation of Positive_regulation of INS 30 0.59 21.58 1.86
38 INT75935 Regulation of MLXIPL 4 0.18 3.82 1.7
39 INT63599 Positive_regulation of Localization of Got1 2 0.46 0.67 1.57
40 INT255787 Positive_regulation of Gene_expression of Sirt1 9 0.67 7.61 1.5
41 INT289575 Gene_expression of Sirt1 47 0.77 29.29 1.47
42 INT36330 Positive_regulation of Positive_regulation of GOT1 4 0.32 4.42 1.26
43 INT109104 Positive_regulation of Protein_catabolism of INS 4 0.50 4.44 1.24
44 INT32120 Binding of Got1 3 0.29 1.98 1.16
45 INT3486 Positive_regulation of Regulation of INS 9 0.47 5.65 1.15
46 INT183046 Transcription of INS 25 0.70 11.14 1.13
47 INT63597 Negative_regulation of Localization of Got1 2 0.43 0.49 1.06
48 INT289553 Positive_regulation of Gene_expression of Sirt1 21 0.69 20.43 1.03
49 INT168065 Binding of Sirt1 13 0.47 4.55 1.02
50 INT58470 Negative_regulation of Binding of INS 14 0.43 7.2 1.01
51 INT3529 Regulation of GOT1 6 0.52 2.4 1.01
52 INT71747 Positive_regulation of Prkaa2 19 0.46 8.76 0.98
53 INT104390 Positive_regulation of Positive_regulation of Got1 3 0.26 1.34 0.83
54 INT167833 Positive_regulation of Ins2 4 0.50 6.52 0.82
55 INT289550 Positive_regulation of Sirt1 25 0.69 13.59 0.8
56 INT12190 Negative_regulation of Localization of Got1 2 0.21 0.98 0.8
57 INT12057 Regulation of Negative_regulation of INS 7 0.40 3.92 0.76
58 INT12099 Localization of GOT1 2 0.35 2.54 0.72
59 INT132497 Negative_regulation of Negative_regulation of Got1 1 0.20 0 0.71
60 INT312830 Regulation of Ins2 2 0.39 1.45 0.66
61 INT183789 Positive_regulation of Phosphorylation of INS 5 0.50 4.87 0.64
62 INT14570 Regulation of Positive_regulation of INS 8 0.45 4.97 0.62
63 INT23239 Positive_regulation of Regulation of Got1 2 0.10 0.27 0.54
64 INT14571 Regulation of Binding of INS 2 0.23 2.44 0.53
65 INT228570 Phosphorylation of Prkaa2 24 0.61 7.9 0.5
66 INT163114 Positive_regulation of Gene_expression of GOT1 7 0.24 8.93 0.5
67 INT289580 Negative_regulation of Sirt1 23 0.58 9.03 0.48
68 INT312821 Binding of Ins2 2 0.37 2.13 0.46
69 INT213286 Positive_regulation of Binding of INS 6 0.50 4.85 0.45
70 INT300291 Phosphorylation of Sirt1 1 0.77 6.07 0.45
71 INT53667 Gene_expression of Ins2 10 0.65 5.65 0.44
72 INT213272 Negative_regulation of Phosphorylation of INS 7 0.40 9.13 0.44
73 INT141799 Transcription of Got1 2 0.35 1.41 0.43
74 INT47387 Negative_regulation of Positive_regulation of GOT1 2 0.26 1.04 0.43
75 INT141796 Negative_regulation of Transcription of Got1 1 0.22 0.43 0.43
76 INT240935 Transcription of Sirt1 2 0.68 0.42 0.42
77 INT340290 Regulation of Transcription of Sirt1 1 0.43 0.13 0.42
78 INT312829 Positive_regulation of Positive_regulation of Ins2 1 0.50 1.73 0.4
79 INT48272 Negative_regulation of Protein_catabolism of Got1 1 0.15 0 0.39
80 INT231341 Negative_regulation of Gene_expression of Got1 2 0.12 1.21 0.38
81 INT48271 Protein_catabolism of Got1 1 0.31 0 0.38
82 INT14569 Positive_regulation of Negative_regulation of INS 4 0.36 3.52 0.37
83 INT70552 Regulation of Gene_expression of Got1 1 0.16 0.18 0.36
84 INT240914 Negative_regulation of Sirt1 9 0.46 3.16 0.34
85 INT183066 Positive_regulation of Transcription of INS 8 0.49 5.31 0.34
86 INT55801 Regulation of Positive_regulation of Got1 3 0.08 2.08 0.33
87 INT289546 Negative_regulation of Gene_expression of Sirt1 5 0.42 3.1 0.31
88 INT204368 Gene_expression of SIRT1 17 0.76 4.48 0.3
89 INT71752 Negative_regulation of Prkaa2 17 0.39 2.81 0.3
90 INT71750 Regulation of Prkaa2 12 0.41 2.98 0.29
91 INT226115 Positive_regulation of PRKAA1 2 0.15 0.45 0.29
92 INT32119 Positive_regulation of Binding of Got1 1 0.13 0.89 0.28
93 INT207293 Negative_regulation of Negative_regulation of INS 12 0.49 6 0.26
94 INT187504 Gene_expression of Prkaa2 5 0.65 1.3 0.22
95 INT55802 Regulation of Gene_expression of Got1 2 0.14 1.23 0.22
96 INT334589 Positive_regulation of Negative_regulation of Got1 1 0.08 1.15 0.21
97 INT253395 Negative_regulation of Phosphorylation of Prkaa2 9 0.39 1.35 0.2
98 INT289551 Regulation of Sirt1 8 0.61 4.46 0.2
99 INT55871 Binding of GOT1 1 0.04 2.22 0.19
100 INT312822 Regulation of Transcription of Ins2 1 0.45 0.71 0.18
101 INT312825 Transcription of Ins2 1 0.69 0.7 0.18
102 INT246620 Negative_regulation of Positive_regulation of Sirt1 2 0.39 1.9 0.17
103 INT253401 Positive_regulation of Positive_regulation of Prkaa2 2 0.33 1.39 0.15
104 INT256111 Regulation of Gene_expression of Sirt1 1 0.32 0.73 0.14
105 INT204365 Positive_regulation of Gene_expression of SIRT1 8 0.68 2.9 0.13
106 INT342900 Negative_regulation of Regulation of GOT1 1 0.04 0.42 0.12
107 INT312828 Negative_regulation of Gene_expression of Ins2 1 0.37 0.8 0.12
108 INT289543 Regulation of Gene_expression of Sirt1 3 0.45 1.81 0.11
109 INT289547 Positive_regulation of Positive_regulation of Sirt1 2 0.69 0.76 0.11
110 INT332681 Regulation of Positive_regulation of Sirt1 1 0.16 0.69 0.11
111 INT187495 Positive_regulation of Gene_expression of Prkaa2 1 0.49 0.09 0.11
112 INT253404 Positive_regulation of Phosphorylation of Prkaa2 3 0.29 1.23 0.09
113 INT355099 Localization of Ins2 1 0.44 0.83 0.09
114 INT289567 Regulation of Negative_regulation of Sirt1 1 0.45 0.74 0.09
115 INT312832 Negative_regulation of Ins2 1 0.37 0.64 0.09
116 INT253390 Negative_regulation of Positive_regulation of Prkaa2 4 0.28 0.76 0.08
117 INT228295 Negative_regulation of Transcription of INS 2 0.43 1.1 0.07
118 INT289574 Negative_regulation of Positive_regulation of Sirt1 1 0.42 0.42 0.07
119 INT256136 Negative_regulation of Binding of Sirt1 1 0.30 0.5 0.07
120 INT38981 Positive_regulation of Gene_expression of Got1 1 0.33 0.65 0.07
121 INT339991 Localization of SIRT1 1 0.34 0.3 0.06
122 INT256137 Positive_regulation of Regulation of Sirt1 1 0.36 0.32 0.05
123 INT318236 Negative_regulation of Gene_expression of SIRT1 1 0.42 0.59 0.05
124 INT289587 Negative_regulation of Negative_regulation of Sirt1 1 0.42 0.65 0.05
125 INT256129 Negative_regulation of Gene_expression of Sirt1 1 0.31 0.4 0.05
126 INT253387 Negative_regulation of Regulation of Prkaa2 1 0.28 0.08 0.05
127 INT297867 Positive_regulation of Gene_expression of Ins2 1 0.48 2.86 0.04
128 INT197485 Regulation of Positive_regulation of GOT1 1 0.01 0.44 0.04
129 INT197486 Positive_regulation of Regulation of GOT1 1 0.01 0.44 0.04
130 INT289584 Binding of Sirt1 3 0.48 1.35 0.03
131 INT270038 Positive_regulation of Positive_regulation of Sirt1 2 0.43 0.44 0.03
132 INT246622 Phosphorylation of Sirt1 2 0.74 0.56 0.03
133 INT204367 Positive_regulation of SIRT1 13 0.68 4.17 0
134 INT204349 Regulation of SIRT1 8 0.61 1.99 0
135 INT256134 Localization of Sirt1 5 0.50 2.99 0
136 INT204353 Transcription of SIRT1 3 0.68 0.67 0
137 INT253402 Binding of Prkaa2 2 0.24 0.43 0
138 INT183060 Regulation of Transcription of INS 2 0.44 0.34 0
139 INT253408 Positive_regulation of Negative_regulation of Prkaa2 1 0.33 0.44 0
140 INT204361 Negative_regulation of SIRT1 1 0.42 0.18 0
141 INT289569 Transcription of Sirt1 1 0.71 0.25 0
142 INT300686 Regulation of Binding of Sirt1 1 0.44 0.06 0
143 INT300287 Localization of Sirt1 1 0.66 1.46 0
144 INT330234 Localization of Prkaa2 1 0.21 0 0
145 INT289583 Regulation of Transcription of Sirt1 1 0.27 0.25 0
146 INT300683 Positive_regulation of Negative_regulation of Sirt1 1 0.45 0 0
147 INT204371 Positive_regulation of Transcription of SIRT1 1 0.49 0.13 0
148 INT253394 Negative_regulation of Negative_regulation of Prkaa2 1 0.28 0.33 0
149 INT318239 Regulation of Transcription of SIRT1 1 0.26 0.45 0
150 INT240932 Negative_regulation of Transcription of Sirt1 1 0.34 0.29 0
151 INT289594 Regulation of Regulation of Sirt1 1 0.45 0.15 0
152 INT350520 Phosphorylation of SIRT1 1 0.25 0.72 0
153 INT204356 Regulation of Gene_expression of SIRT1 1 0.61 0.29 0
154 INT204331 Binding of SIRT1 1 0.47 0.39 0
155 INT222960 Gene_expression of MLXIPL 1 0.01 0 0
156 INT238857 Phosphorylation of PRKAA1 1 0.01 1.73 0
157 INT300685 Positive_regulation of Binding of Sirt1 1 0.67 0 0
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