GO:0055093

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Name response to hyperoxia
Categary Process
Go Slim No
Go Link GO:0055093
Unique Molecular Interactions 780
Total Molecular Interactions 1098
Total Single Events 10551
Pain Genes Associated 40

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to hyperoxia. They are ordered first by their pain relevance and then by number of times they were reported for response to hyperoxia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69229 Ngf Positive_regulation of Gene_expression of Bdnf 6 0.76 8.19 6.66
2 INT131249 Binding of Bdnf and Ntrk2 11 0.41 4 6.25
3 INT240653 Ngf Positive_regulation of Positive_regulation of Bdnf 1 0.55 2.97 4.23
4 INT69032 IL18 Positive_regulation of IFNA1 12 0.23 7.87 3.83
5 INT132862 Ngf Positive_regulation of Bdnf 4 0.46 4.05 3.65
6 INT152699 Bdnf Positive_regulation of Ltp 5 0.05 1.22 2.95
7 INT69030 IL18 Positive_regulation of IL12A 3 0.31 5.57 2.72
8 INT180779 Bdnf Regulation of Calca 1 0.09 0.23 2.71
9 INT128044 Bdnf Positive_regulation of Ephb1 2 0.31 1.89 2.57
10 INT184262 Binding of AGER and HMGB1 1 0.34 4.49 2.17
11 INT205152 Binding of CD44 and MMP9 23 0.35 17.13 1.85
12 INT122964 FSCN1 Positive_regulation of Bdnf 1 0.01 1.14 1.79
13 INT102160 Binding of Mmp2 and Mmp9 3 0.28 2.87 1.75
14 INT278223 Binding of NOS3 and ACSM3 1 0.41 6.32 1.65
15 INT24689 Binding of PLAT and Serpine1 1 0.00 3.77 1.64
16 INT113337 EPO Positive_regulation of JAK2 1 0.76 2.8 1.55
17 INT222335 Binding of Bdnf and Ngfr 3 0.05 2.66 1.48
18 INT180767 Bdnf Positive_regulation of Gene_expression of Calca 1 0.17 0 1.45
19 INT180804 Bdnf Positive_regulation of Gene_expression of Sorbs1 1 0.01 0 1.44
20 INT180768 Bdnf Regulation of Localization of Trpv1 1 0.13 1.21 1.43
21 INT134764 Ghrl Regulation of Gene_expression of NOS3 1 0.02 2.66 1.4
22 INT56093 FGFR1 Regulation of Gene_expression of SERPINE1 1 0.23 1.71 1.37
23 INT176368 IL18 Positive_regulation of Gene_expression of IFNA1 1 0.16 2.53 1.35
24 INT160585 IL18 Positive_regulation of Gene_expression of OPRM1 1 0.09 0.54 1.35
25 INT261463 Binding of Drd1a and Sftpd 1 0.12 0.13 1.35
26 INT178986 Binding of MMP9 and TIMP1 4 0.47 2.58 1.33
27 INT56087 TNF Regulation of Gene_expression of SERPINE1 1 0.43 1.67 1.33
28 INT180771 Calca Regulation of Positive_regulation of Bdnf 1 0.18 0 1.32
29 INT96708 Bdnf Positive_regulation of Localization of SST 1 0.01 0 1.3
30 INT113844 CDKN1A Negative_regulation of CDK2 4 0.49 1.18 1.27
31 INT42580 CAT Negative_regulation of POMC 1 0.20 0.42 1.26
32 INT202042 CAMK2N2 Negative_regulation of MMP9 1 0.01 0.73 1.25
33 INT50386 Bdnf Regulation of Npy 1 0.21 0.47 1.24
34 INT50385 Bdnf Positive_regulation of Pomc 1 0.22 0.47 1.23
35 INT52955 Binding of Slc6a3 and Pdpn 1 0.17 1.11 1.22
36 INT187172 RPS3AP9 Negative_regulation of MMP9 1 0.00 0.89 1.2
37 INT334351 Bdnf Regulation of Positive_regulation of Ephb1 1 0.18 1.27 1.2
38 INT148437 Binding of Bdnf and Ngf 2 0.32 1.9 1.17
39 INT148435 Binding of Bdnf and Gdnf 2 0.35 1.9 1.17
40 INT60990 Bdnf Negative_regulation of Th 1 0.15 0 1.17
41 INT68160 Alox5 Positive_regulation of Positive_regulation of Pla2g1b 1 0.03 0.64 1.13
42 INT110671 Binding of Cnr1 and Alox5 1 0.07 0.2 1.13
43 INT68164 Mthfs Positive_regulation of Positive_regulation of Alox5 1 0.00 0.64 1.13
44 INT68167 Alox5 Positive_regulation of Positive_regulation of Mthfs 1 0.00 0.64 1.13
45 INT110669 Binding of Alox5 and Trpv1 1 0.07 0.2 1.13
46 INT68157 Alox5 Positive_regulation of Positive_regulation of Pdpk1 1 0.01 0.64 1.13
47 INT68156 Pla2g1b Positive_regulation of Positive_regulation of Alox5 1 0.03 0.64 1.13
48 INT68165 Alox5 Positive_regulation of Pdpk1 1 0.01 0.63 1.12
49 INT132683 Bdnf Positive_regulation of Phosphorylation of Grin2a 1 0.00 0.93 1.11
50 INT120313 Gnrhr Negative_regulation of Mmp2 1 0.03 0.85 1.07
51 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
52 INT87320 Ngf Regulation of Gene_expression of Bdnf 2 0.38 0.97 1.06
53 INT73311 Binding of Oprm1 and Pdpn 1 0.08 0.71 1.06
54 INT56990 Cat Regulation of Efs 1 0.26 0 1.05
55 INT134534 Binding of Bdnf and Psds1 1 0.01 0 1.05
56 INT312097 ELANE Regulation of ALOX5 1 0.08 1.75 1.05
57 INT133650 Epo Negative_regulation of TNF 1 0.35 2.7 1.04
58 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02
59 INT203178 IL18 Positive_regulation of Gene_expression of Lts1 1 0.01 1.98 1.02
60 INT224856 Binding of Bdnf and Eef2 1 0.14 0 1.02
61 INT130232 Binding of Cat and Sod1 1 0.35 0.3 0.98
62 INT130231 Positive_regulation of Binding of Cat and Sod1 1 0.46 0.3 0.98
63 INT187111 TIMP2 Regulation of MMP9 1 0.23 1.47 0.97
64 INT133652 Epo Negative_regulation of Gene_expression of TNF 1 0.35 2.64 0.96
65 INT266659 Binding of MMP9 and MOCS1 1 0.01 1.71 0.94
66 INT220031 Casp3 Positive_regulation of Gene_expression of Nos3 1 0.04 0 0.92
67 INT185417 Binding of ALOX5 and PLA2G2A 4 0.16 3.13 0.9
68 INT219037 Creb1 Positive_regulation of Transcription of Bdnf 2 0.43 1.07 0.9
69 INT180772 Bdnf Regulation of Trpv1 1 0.11 0.29 0.9
70 INT180777 Bdnf Regulation of Gene_expression of Trpv1 1 0.18 0.29 0.9
71 INT92404 PSRC1 Regulation of CDKN1A 1 0.33 0.66 0.89
72 INT152700 Negative_regulation of Nfkb1 Negative_regulation of Bdnf 1 0.04 0.15 0.89
73 INT152701 Nfkb1 Negative_regulation of Bdnf 1 0.04 0.15 0.89
74 INT152694 Negative_regulation of Nfkb1 Negative_regulation of Bdnf 1 0.24 0.15 0.88
75 INT48463 Bdnf Positive_regulation of Gene_expression of Sst 1 0.25 0 0.88
76 INT152695 Nfkb1 Negative_regulation of Bdnf 1 0.24 0.15 0.88
77 INT261783 Bdnf Regulation of Gene_expression of Slc12a5 1 0.09 0 0.87
78 INT215596 Bdnf Positive_regulation of Negative_regulation of Slc12a5 1 0.14 0.76 0.86
79 INT91992 IGKV1-22 Negative_regulation of Sell 1 0.40 0.31 0.86
80 INT261461 Positive_regulation of Akr1d1 Regulation of Sftpd 1 0.01 0 0.86
81 INT110315 Negative_regulation of ALOX5 Negative_regulation of Gene_expression of TNF 1 0.47 0.74 0.85
82 INT261786 Bdnf Negative_regulation of Slc12a5 1 0.14 0.05 0.85
83 INT102931 Nos3 Positive_regulation of Nos2 1 0.43 1.63 0.83
84 INT261458 Akr1d1 Regulation of Sftpd 1 0.01 0 0.82
85 INT322266 Binding of LIG4 and NOS3 1 0.02 2.35 0.82
86 INT102932 Nos3 Positive_regulation of NOS1 1 0.03 1.63 0.82
87 INT271193 Creb1 Regulation of Bdnf 1 0.15 0.28 0.81
88 INT352201 Negative_regulation of ALOX5 Negative_regulation of Cpox 1 0.02 0.89 0.81
89 INT128042 Bdnf Positive_regulation of Phosphorylation of Ephb1 1 0.22 0.2 0.8
90 INT180782 Bdnf Positive_regulation of Calca 1 0.16 0.77 0.8
91 INT226371 IL18 Positive_regulation of IL4 4 0.05 2.49 0.79
92 INT128041 Bdnf Positive_regulation of Trib3 1 0.10 0.29 0.79
93 INT196525 Binding of MMP2 and MMP9 2 0.32 2.49 0.78
94 INT102163 Binding of TNF and Mmp9 1 0.12 0.88 0.78
95 INT102161 Binding of TNF and Mmp2 1 0.10 0.88 0.78
96 INT203164 PTGER2 Regulation of ALOX5 1 0.00 0.9 0.78
97 INT224280 Bdnf Positive_regulation of Creb1 3 0.30 0.62 0.77
98 INT203171 PTGER2 Negative_regulation of ALOX5 1 0.01 0.89 0.77
99 INT224281 Bdnf Regulation of Gene_expression of Gap43 1 0.36 0.4 0.77
100 INT261447 Sftpd Positive_regulation of Akr1d1 1 0.01 0 0.77
101 INT102159 Binding of Adam17 and Mmp2 1 0.18 0.87 0.77
102 INT224283 Bdnf Regulation of Gene_expression of Calca 1 0.19 0.35 0.76
103 INT295711 MMP9 Positive_regulation of Localization of VEGFA 1 0.06 0.29 0.74
104 INT113552 Binding of PLAU and PLAUR 4 0.31 3.09 0.72
105 INT180765 Calca Regulation of Binding of Bdnf 1 0.15 0.15 0.72
106 INT224580 Gene_expression of IL18 Positive_regulation of SERPINH1 1 0.00 1.34 0.7
107 INT159569 Negative_regulation of Alox5 Negative_regulation of Gene_expression of Fos 1 0.37 0.4 0.7
108 INT295720 PTGER2 Regulation of MMP9 1 0.01 0.53 0.7
109 INT219035 Nkx1-1 Regulation of Gene_expression of Bdnf 1 0.13 0.88 0.7
110 INT224892 Bdnf Regulation of Localization of Ltp 1 0.03 0.17 0.69
111 INT224893 Bdnf Regulation of Ltp 1 0.03 0.17 0.69
112 INT263049 Positive_regulation of Binding of Mmp2 and Mmp9 1 0.35 0.83 0.69
113 INT161186 Bdnf Regulation of Gene_expression of Ntrk2 1 0.44 1.05 0.68
114 INT180805 Bdnf Regulation of Sorbs1 1 0.01 0.14 0.67
115 INT161183 NMS Positive_regulation of Gene_expression of Bdnf 1 0.40 1.3 0.67
116 INT180961 Binding of MOCS1 and PLAU 1 0.00 0.61 0.67
117 INT220032 Nos1 Positive_regulation of Nos3 1 0.32 0.45 0.66
118 INT152298 Mmp9 Negative_regulation of Tsc22d1 1 0.13 0.16 0.66
119 INT152299 Mmp2 Negative_regulation of Tsc22d1 1 0.16 0.16 0.66
120 INT152296 Regulation of Mmp9 Negative_regulation of Tsc22d1 1 0.08 0.16 0.66
121 INT152297 Mmp2 Negative_regulation of Mmp9 1 0.39 0.16 0.65
122 INT82306 Bdnf Positive_regulation of Gene_expression of Fos 1 0.68 0.64 0.65
123 INT160119 EPO Regulation of Gene_expression of NFKB1 1 0.02 0.2 0.64
124 INT261457 Sftpd Positive_regulation of Vta1 1 0.10 0 0.63
125 INT113338 Binding of EPO and KNCN 1 0.02 1.39 0.62
126 INT302469 F2 Positive_regulation of Gene_expression of MMP9 1 0.01 1.82 0.62
127 INT166398 CDKN1B Regulation of Gene_expression of CDKN1A 1 0.46 0.83 0.61
128 INT95431 Il1a Regulation of Mmp2 1 0.48 0.25 0.61
129 INT166399 CDKN1A Regulation of Gene_expression of CDKN1B 1 0.46 0.83 0.61
130 INT166395 CDKN1A Regulation of Gene_expression of IFI27 1 0.32 0.83 0.61
131 INT93690 Bdnf Regulation of Localization of Tacr1 1 0.10 0.28 0.61
132 INT166402 CDKN1A Regulation of Gene_expression of TP53 1 0.27 0.83 0.61
133 INT257717 Binding of Bdnf and Vgf 1 0.25 0.86 0.61
134 INT166392 IFI27 Regulation of Gene_expression of CDKN1A 1 0.32 0.83 0.61
135 INT284089 Binding of NTRK2 and SERPINE1 1 0.27 0.73 0.61
136 INT95434 Mmp9 Positive_regulation of Positive_regulation of Il1a 1 0.42 0.23 0.61
137 INT95433 Mmp3 Regulation of Mmp2 1 0.17 0.24 0.6
138 INT271194 Binding of Bdnf and Gopc 1 0.03 0.49 0.6
139 INT92403 PSRC1 Regulation of Positive_regulation of CDKN1A 1 0.33 0.45 0.6
140 INT295724 CXCL12 Positive_regulation of MMP9 1 0.02 0.32 0.6
141 INT95432 Il1a Positive_regulation of Positive_regulation of Mmp9 1 0.37 0.25 0.6
142 INT95430 Mmp9 Positive_regulation of Mmp3 1 0.38 0.24 0.6
143 INT295721 CSF2 Positive_regulation of MMP9 1 0.06 0.32 0.6
144 INT270100 Negative_regulation of Binding of ALOX5 and PLA2G2A 1 0.01 0.51 0.59
145 INT175700 Nos3 Negative_regulation of smc 1 0.01 1.05 0.59
146 INT202038 MMP9 Positive_regulation of IL8 1 0.05 0.29 0.59
147 INT164455 Ngf Negative_regulation of Bdnf 1 0.05 0.59 0.59
148 INT257715 Bdnf Positive_regulation of Transcription of Vgf 1 0.35 0.66 0.57
149 INT56088 TGFB1 Positive_regulation of Transcription of SERPINE1 1 0.46 0.83 0.57
150 INT270102 ALOX5 Negative_regulation of PLA2G2A 1 0.01 0.49 0.57
151 INT175626 TIMP1 Positive_regulation of Gene_expression of MMP9 1 0.03 0.72 0.57
152 INT176370 IL18BP Negative_regulation of IL18 1 0.15 0.76 0.56
153 INT173556 TIMP1 Negative_regulation of MMP9 1 0.02 0 0.56
154 INT175623 TIMP1 Positive_regulation of MMP9 1 0.03 0.71 0.56
155 INT145718 Positive_regulation of Plat Positive_regulation of Bdnf 1 0.20 0 0.56
156 INT147273 Bdnf Regulation of Syp 1 0.24 0 0.56
157 INT261481 Positive_regulation of Binding of Bdnf and Ntrk2 1 0.02 0.21 0.56
158 INT113548 NFKB1 Regulation of Localization of PLAU 1 0.26 1.93 0.55
159 INT147274 Bdnf Regulation of Gap43 1 0.37 0 0.55
160 INT147575 Binding of Ahr and Cyp1a1 2 0.15 0.15 0.54
161 INT147579 Binding of ATF4 and Cyp1a1 1 0.01 0.15 0.54
162 INT226360 IL18 Positive_regulation of Gene_expression of IL4 1 0.05 2.66 0.54
163 INT278228 Binding of MBNL1 and NOS3 1 0.05 2.06 0.54
164 INT226348 IL18 Positive_regulation of Gene_expression of IL13 1 0.03 2.66 0.54
165 INT143854 Ngf Regulation of Transcription of Bdnf 1 0.09 0.61 0.53
166 INT143862 Bdnf Positive_regulation of Gene_expression of NUP214 1 0.27 0.61 0.52
167 INT205728 Mmp9 Positive_regulation of Gene_expression of Mmp3 1 0.29 0 0.52
168 INT205727 Mmp3 Positive_regulation of Gene_expression of Mmp9 1 0.29 0 0.52
169 INT143859 Bdnf Positive_regulation of Gene_expression of Nfatc1 1 0.00 0.61 0.52
170 INT162500 AHR Regulation of CYP1A1 3 0.19 0.18 0.51
171 INT196524 Binding of MMP1 and MMP9 1 0.31 0.74 0.51
172 INT196519 Positive_regulation of Binding of MMP1 and MMP9 1 0.42 0.74 0.51
173 INT271191 Bdnf Regulation of Slc6a4 1 0.03 0.29 0.51
174 INT187116 TIMP2 Negative_regulation of MMP9 1 0.36 1.37 0.5
175 INT224853 Binding of Bdnf and Eif4e 1 0.10 0 0.5
176 INT230532 LILRB1 Positive_regulation of Gene_expression of Mmp2 1 0.14 1.04 0.5
177 INT230533 LILRB1 Positive_regulation of Positive_regulation of Mmp9 1 0.20 1.03 0.5
178 INT114543 Bdnf Positive_regulation of Prkcg 1 0.21 0 0.49
179 INT257720 Bdnf Regulation of Vgf 1 0.19 0.64 0.49
180 INT219038 Creb1 Regulation of Gene_expression of Bdnf 1 0.25 0.25 0.49
181 INT341428 EPO Positive_regulation of NGF 1 0.52 0.37 0.48
182 INT127664 Negative_regulation of PDE4A Negative_regulation of MMP9 1 0.37 0.76 0.48
183 INT341427 EPO Positive_regulation of BDNF 1 0.52 0.36 0.48
184 INT127665 Negative_regulation of PDE4A Negative_regulation of Transcription of MMP9 1 0.37 0.76 0.48
185 INT251163 Gene_expression of Alox5 Positive_regulation of Trpv1 1 0.02 0.11 0.48
186 INT273110 Bdnf Regulation of Positive_regulation of Gria1 1 0.43 0 0.47
187 INT341426 EPO Regulation of NGF 1 0.51 0.5 0.47
188 INT341425 EPO Regulation of BDNF 1 0.51 0.5 0.47
189 INT309127 Edc4 Positive_regulation of Bdnf 1 0.04 0.37 0.47
190 INT303445 Mmp3 Positive_regulation of Mmp9 1 0.01 1.19 0.47
191 INT312112 ELANE Regulation of Transcription of ALOX5 1 0.09 0.82 0.47
192 INT261450 Binding of Sftpd and Ptgdr 1 0.08 0.19 0.47
193 INT103025 Calca Positive_regulation of Nos3 1 0.25 0.41 0.46
194 INT103027 Ptgis Positive_regulation of Nos3 1 0.06 0.42 0.46
195 INT95276 Obfc2a Negative_regulation of Nos3 1 0.02 1.02 0.46
196 INT222284 Negative_regulation of Casp1 Negative_regulation of Il18 1 0.01 0.79 0.46
197 INT184291 Binding of AGER and Crp 1 0.01 1.23 0.46
198 INT103030 Calca Positive_regulation of Positive_regulation of Nos3 1 0.26 0.41 0.46
199 INT22674 Binding of SERPINE1 and PLAT 7 0.04 0.65 0.45
200 INT354395 TNFSF12 Regulation of Gene_expression of IL18 1 0.47 0.79 0.45

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to hyperoxia. They are ordered first by their pain relevance and then by number of times they were reported in response to hyperoxia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT16260 Gene_expression of Bdnf 671 0.78 283.44 339.1
2 INT16259 Positive_regulation of Bdnf 336 0.70 183.48 209.82
3 INT16253 Positive_regulation of Gene_expression of Bdnf 196 0.70 92.67 113.01
4 INT67682 Localization of Bdnf 204 0.81 72.36 88.92
5 INT47690 Regulation of Bdnf 118 0.62 53.02 64.5
6 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81
7 INT47680 Regulation of Gene_expression of Bdnf 92 0.62 41.61 53.24
8 INT83199 Gene_expression of Nos3 193 0.78 100.72 51.57
9 INT47683 Negative_regulation of Bdnf 92 0.59 47.53 43.55
10 INT16261 Transcription of Bdnf 101 0.72 49.41 40.64
11 INT68975 Gene_expression of Mmp9 111 0.78 79.57 38.55
12 INT99610 Localization of MMP9 126 0.79 48.46 32.67
13 INT29503 Gene_expression of Mmp2 95 0.77 56.92 31.68
14 INT5418 Negative_regulation of Alox5 108 0.57 42.09 31.17
15 INT68973 Positive_regulation of Mmp9 89 0.52 58.56 30.04
16 INT9053 Negative_regulation of ALOX5 97 0.58 40.34 29.94
17 INT67620 Negative_regulation of Gene_expression of Bdnf 53 0.59 22.45 28.5
18 INT11361 Gene_expression of SERPINE1 183 0.78 136.45 27.97
19 INT47685 Positive_regulation of Positive_regulation of Bdnf 32 0.70 20.05 27.03
20 INT73047 Positive_regulation of MMP9 133 0.68 73.22 26.42
21 INT69036 Gene_expression of IL18 99 0.77 77.92 25.95
22 INT96557 Binding of Bdnf 46 0.47 21.74 24.26
23 INT74682 Positive_regulation of Mmp2 72 0.69 40.46 21.73
24 INT12951 Negative_regulation of Cat 126 0.57 64.39 20.61
25 INT87861 Gene_expression of Il18 33 0.78 30.44 18.42
26 INT28215 Gene_expression of CDKN1A 196 0.76 113.9 18.3
27 INT17442 Gene_expression of ALOX5 110 0.75 51.55 18.29
28 INT9246 Positive_regulation of Cat 113 0.70 52.73 18.04
29 INT83198 Positive_regulation of Nos3 78 0.64 35.69 17.71
30 INT139830 Gene_expression of AGER 47 0.75 41.71 16.53
31 INT96299 Positive_regulation of Localization of Bdnf 35 0.70 15.67 16.09
32 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
33 INT12950 Gene_expression of Cat 85 0.75 35.94 15.76
34 INT103245 Positive_regulation of Gene_expression of MMP9 64 0.68 36.86 15.7
35 INT11636 Positive_regulation of SERPINE1 85 0.69 68.73 14.8
36 INT75502 Positive_regulation of CDKN1A 123 0.68 70.75 14.74
37 INT2843 Gene_expression of Epo 100 0.78 62.01 14.66
38 INT23344 Gene_expression of Alox5 60 0.75 28.2 13.82
39 INT18012 Gene_expression of EPO 169 0.78 108.36 13.75
40 INT15921 Positive_regulation of Serpine1 85 0.68 81.24 13.4
41 INT47692 Negative_regulation of Positive_regulation of Bdnf 18 0.59 9.64 13.14
42 INT83200 Positive_regulation of Gene_expression of Nos3 48 0.70 24.75 12.99
43 INT83201 Gene_expression of NOS3 93 0.78 47.16 12.48
44 INT11359 Gene_expression of PLAU 84 0.76 49.54 12.31
45 INT21160 Gene_expression of Sell 28 0.64 19.37 12.18
46 INT56048 Positive_regulation of Transcription of Bdnf 24 0.70 8.33 11.83
47 INT93715 Negative_regulation of MMP9 69 0.55 36.05 11.73
48 INT68976 Positive_regulation of Gene_expression of Mmp9 34 0.42 28.21 11.28
49 INT74681 Positive_regulation of Gene_expression of Mmp2 23 0.55 15.58 10.74
50 INT22132 Positive_regulation of CAT 41 0.67 18.64 10.67
51 INT89282 Regulation of MMP9 39 0.60 25.45 10.34
52 INT2378 Negative_regulation of SERPINE1 47 0.59 34.55 9.9
53 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
54 INT126031 Negative_regulation of Gene_expression of MMP9 40 0.57 22.71 9.79
55 INT95271 Negative_regulation of Nos3 46 0.53 24.1 9.71
56 INT57162 Positive_regulation of Gene_expression of CDKN1A 64 0.68 35.3 9.69
57 INT87863 Positive_regulation of IL18 40 0.69 34.08 9.53
58 INT125247 Negative_regulation of Mmp9 42 0.43 23.68 9.37
59 INT187190 Positive_regulation of Localization of MMP9 27 0.68 8.1 8.93
60 INT111903 Regulation of Mmp2 9 0.61 3.95 7.98
61 INT76091 Positive_regulation of NOS3 48 0.61 18.4 7.92
62 INT15918 Gene_expression of Serpine1 60 0.62 41.73 7.72
63 INT124297 Gene_expression of Sod2 112 0.77 65.65 7.64
64 INT94127 Positive_regulation of Il18 14 0.69 14 7.47
65 INT184281 Binding of AGER 25 0.37 23.06 7.32
66 INT4228 Gene_expression of CAT 50 0.75 20.62 7.18
67 INT103824 Positive_regulation of SOD2 26 0.70 17.42 7.17
68 INT39282 Negative_regulation of SOD2 27 0.59 16.89 7.03
69 INT3098 Positive_regulation of Epo 46 0.70 28.27 7
70 INT15872 Positive_regulation of EPO 74 0.70 45.35 6.67
71 INT21161 Positive_regulation of Sell 11 0.58 8.64 6.57
72 INT91721 Binding of IL18 21 0.48 21.17 6.56
73 INT71116 Gene_expression of Plau 29 0.77 4.94 6.45
74 INT83712 Transcription of Nos3 19 0.69 13.09 6.31
75 INT3738 Regulation of Epo 25 0.61 13.73 6.18
76 INT91065 Regulation of Transcription of Bdnf 13 0.62 12.48 6.13
77 INT91657 Negative_regulation of IL18 20 0.48 15.97 6.12
78 INT152293 Regulation of Mmp9 9 0.49 6.57 6.01
79 INT104330 Negative_regulation of CDKN1A 57 0.58 39.93 5.88
80 INT56047 Negative_regulation of Transcription of Bdnf 16 0.59 8.02 5.67
81 INT11360 Localization of SERPINE1 41 0.80 33.98 5.61
82 INT185 Regulation of Cyp1a1 18 0.54 2.71 5.56
83 INT87468 Negative_regulation of Mmp2 24 0.57 10.79 5.55
84 INT113420 Positive_regulation of Gene_expression of IL18 22 0.69 19.96 5.53
85 INT28164 Regulation of ALOX5 25 0.60 12.76 5.47
86 INT99606 Negative_regulation of Localization of MMP9 23 0.57 7.15 5.47
87 INT35536 Negative_regulation of CAT 26 0.57 14.39 5.38
88 INT28165 Positive_regulation of ALOX5 38 0.47 10.8 5.37
89 INT38366 Regulation of Cat 45 0.62 23.45 5.34
90 INT110666 Phosphorylation of Bdnf 12 0.69 5.67 5.21
91 INT2435 Negative_regulation of Cyp1a1 15 0.58 3.32 5.16
92 INT67681 Negative_regulation of Localization of Bdnf 12 0.50 4.37 5.07
93 INT6577 Regulation of Alox5 18 0.47 9.19 5.06
94 INT186 Positive_regulation of Cyp1a1 30 0.70 5 5.02
95 INT15920 Regulation of Serpine1 34 0.42 17.36 4.89
96 INT160055 Localization of CDKN1A 15 0.78 12.56 4.83
97 INT52952 Binding of Pdpn 8 0.13 3.57 4.79
98 INT62942 Negative_regulation of Gene_expression of Sell 5 0.49 8.22 4.71
99 INT30355 Positive_regulation of Gene_expression of Alox5 10 0.67 14.61 4.69
100 INT29502 Localization of Mmp2 18 0.79 3.49 4.64
101 INT15995 Positive_regulation of Alox5 18 0.49 3.94 4.63
102 INT54895 Binding of Epo 24 0.48 11.38 4.48
103 INT11354 Regulation of Gene_expression of SERPINE1 11 0.61 8.66 4.42
104 INT11635 Positive_regulation of Gene_expression of SERPINE1 35 0.68 24.57 4.26
105 INT11634 Regulation of SERPINE1 24 0.62 20.06 4.26
106 INT125896 Negative_regulation of Gene_expression of Mmp9 15 0.43 13.73 4.18
107 INT99608 Transcription of MMP9 18 0.65 9.67 4.11
108 INT83991 Regulation of Nos3 25 0.44 9.89 4.06
109 INT102515 Binding of Nos3 19 0.45 9.41 4.01
110 INT17548 Negative_regulation of Serpine1 30 0.57 24.69 3.93
111 INT79723 Positive_regulation of Sod2 34 0.70 24.61 3.92
112 INT133312 Binding of MMP9 25 0.42 16.79 3.83
113 INT35175 Localization of IL18 18 0.80 12.96 3.83
114 INT141658 Positive_regulation of Gene_expression of Sod2 51 0.69 35.6 3.71
115 INT44254 Regulation of Gene_expression of ALOX5 12 0.43 7.06 3.65
116 INT82305 Regulation of Localization of Bdnf 10 0.40 3 3.62
117 INT17716 Gene_expression of Aldh2 14 0.77 4.38 3.61
118 INT99453 Gene_expression of SOD2 25 0.77 13.28 3.6
119 INT105222 Positive_regulation of Plau 18 0.54 8.52 3.5
120 INT148151 Regulation of Il18 7 0.28 5.4 3.5
121 INT184270 Negative_regulation of AGER 8 0.32 10.48 3.45
122 INT68974 Localization of Mmp9 10 0.80 4.84 3.35
123 INT82796 Regulation of CDKN1A 22 0.53 9.83 3.33
124 INT70958 Binding of NOS3 19 0.37 11.84 3.29
125 INT10476 Binding of ALOX5 26 0.36 7.69 3.2
126 INT48462 Positive_regulation of Negative_regulation of Bdnf 8 0.70 1 3.2
127 INT183212 Positive_regulation of Regulation of Bdnf 4 0.45 1.57 3.14
128 INT12948 Positive_regulation of Gene_expression of Cat 17 0.67 6.46 3.12
129 INT53065 Negative_regulation of Gene_expression of EPO 15 0.49 16.39 3.12
130 INT92814 Negative_regulation of NOS3 25 0.51 20.67 3.07
131 INT75505 Regulation of Gene_expression of CDKN1A 24 0.60 12.24 3.07
132 INT35448 Negative_regulation of Gene_expression of ALOX5 11 0.57 5.28 3.03
133 INT184286 Regulation of AGER 1 0.46 6.7 3
134 INT71117 Positive_regulation of Gene_expression of Plau 9 0.69 0.22 2.92
135 INT176383 Negative_regulation of Binding of IL18 1 0.35 5.91 2.91
136 INT45503 Binding of EPO 42 0.48 24.85 2.88
137 INT91869 Transcription of NOS3 13 0.67 6.81 2.86
138 INT75499 Positive_regulation of Positive_regulation of CDKN1A 12 0.60 7.28 2.84
139 INT67580 Regulation of Gene_expression of Sell 5 0.51 1.86 2.8
140 INT22212 Gene_expression of CYP1A1 34 0.76 10.11 2.77
141 INT8112 Regulation of EPO 38 0.58 22.04 2.76
142 INT143952 Regulation of Gene_expression of MMP9 14 0.53 10.16 2.73
143 INT101883 Regulation of Gene_expression of Nos3 11 0.52 6.71 2.73
144 INT139562 Transcription of IL18 10 0.68 6.14 2.73
145 INT64791 Negative_regulation of Sell 8 0.57 4.17 2.73
146 INT90675 Negative_regulation of Gene_expression of Nos3 15 0.46 11.11 2.7
147 INT119516 Positive_regulation of Phosphorylation of Bdnf 3 0.21 2.81 2.68
148 INT67884 Positive_regulation of PLAU 15 0.68 11.21 2.61
149 INT222289 Localization of Il18 4 0.30 3.24 2.58
150 INT8111 Localization of EPO 32 0.81 19.53 2.54
151 INT34905 Positive_regulation of Gene_expression of ALOX5 18 0.50 7.46 2.46
152 INT183810 Positive_regulation of Positive_regulation of MMP9 9 0.52 4.15 2.46
153 INT184280 Positive_regulation of AGER 8 0.52 9.05 2.43
154 INT11357 Negative_regulation of Gene_expression of PLAU 10 0.56 5.3 2.38
155 INT186456 Gene_expression of SFTPC 2 0.75 11.46 2.38
156 INT22129 Positive_regulation of Gene_expression of CAT 11 0.67 4.23 2.37
157 INT22679 Binding of SERPINE1 25 0.36 17.33 2.36
158 INT45597 Negative_regulation of Epo 22 0.59 12.47 2.35
159 INT133567 Regulation of IL18 11 0.50 9.54 2.31
160 INT148152 Binding of Il18 4 0.46 4.44 2.19
161 INT15922 Positive_regulation of Positive_regulation of Serpine1 6 0.31 8.34 2.16
162 INT152286 Regulation of Gene_expression of Mmp9 5 0.36 3.95 2.15
163 INT109334 Regulation of SOD2 13 0.60 7.48 2.14
164 INT168945 Positive_regulation of Binding of Bdnf 4 0.50 1.7 2.14
165 INT184284 Regulation of Gene_expression of AGER 1 0.34 4.95 2.11
166 INT26736 Localization of Alox5 7 0.49 3.72 2.09
167 INT263046 Negative_regulation of Gene_expression of Mmp2 7 0.34 5.98 2.09
168 INT125246 Negative_regulation of Positive_regulation of Mmp9 5 0.27 5.34 2.09
169 INT82166 Regulation of NOS3 14 0.54 7.57 2.08
170 INT97558 Gene_expression of Sftpd 6 0.47 3.35 2.07
171 INT94128 Positive_regulation of Gene_expression of Il18 6 0.50 3.64 2.06
172 INT118305 Negative_regulation of Gene_expression of IL18 7 0.39 6.52 2.05
173 INT91594 Localization of NOS3 12 0.78 5.39 2.02
174 INT98888 Negative_regulation of Gene_expression of Il18 3 0.43 1.72 2.02
175 INT36267 Positive_regulation of CYP1A1 29 0.69 11.09 2.01
176 INT103244 Protein_catabolism of MMP9 12 0.72 11.81 2.01
177 INT11905 Protein_catabolism of EPO 6 1.00 2.36 2
178 INT19409 Binding of Cyp1a1 12 0.48 2.58 1.97
179 INT28926 Negative_regulation of Aldh2 11 0.58 1.25 1.97
180 INT146793 Positive_regulation of Tp53 30 0.70 32.93 1.94
181 INT20251 Binding of Alox5 7 0.32 5.33 1.93
182 INT11364 Regulation of Gene_expression of PLAU 4 0.58 3.23 1.92
183 INT102158 Protein_catabolism of Mmp9 7 0.65 5.43 1.91
184 INT48722 Negative_regulation of Gene_expression of SERPINE1 12 0.43 7.66 1.85
185 INT15742 Negative_regulation of EPO 37 0.59 17.44 1.84
186 INT100874 Protein_catabolism of Plau 4 0.77 1.51 1.83
187 INT92622 Regulation of Positive_regulation of Bdnf 4 0.39 2.16 1.81
188 INT152292 Regulation of Gene_expression of Mmp2 6 0.61 3.46 1.76
189 INT60999 Localization of Nos3 12 0.74 5.28 1.75
190 INT107923 Regulation of Gene_expression of NOS3 11 0.61 2.73 1.73
191 INT48720 Transcription of SERPINE1 11 0.68 4.76 1.67
192 INT184273 Localization of AGER 1 0.60 3.59 1.67
193 INT48813 Negative_regulation of Plau 12 0.44 3.46 1.66
194 INT23176 Gene_expression of Pdpn 6 0.75 4.06 1.65
195 INT104331 Negative_regulation of Gene_expression of CDKN1A 24 0.57 13.68 1.63
196 INT133443 Transcription of Mmp2 8 0.69 2.48 1.61
197 INT186724 Negative_regulation of Transcription of MMP9 5 0.37 1.59 1.57
198 INT115721 Positive_regulation of Gene_expression of PLAU 11 0.67 7.66 1.55
199 INT83466 Localization of Sell 3 0.08 3.44 1.54
200 INT83467 Positive_regulation of Localization of Sell 2 0.07 3.45 1.54
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