GO:0060009

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Name Sertoli cell development
Categary Process
Go Slim No
Go Link GO:0060009
Unique Molecular Interactions 94
Total Molecular Interactions 155
Total Single Events 1006
Pain Genes Associated 12

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for Sertoli cell development. They are ordered first by their pain relevance and then by number of times they were reported for Sertoli cell development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26
2 INT88279 Ngf Positive_regulation of Ntrk1 5 0.76 3.06 5.23
3 INT82023 Binding of Ntrk1 and Ngf 5 0.53 3.48 3.92
4 INT221746 Ngf Positive_regulation of Ntrk1 1 0.02 0.92 2.88
5 INT83418 Binding of OPRL1 and Ntrk1 1 0.02 0 1.91
6 INT108385 Binding of Crygs and Ntrk1 1 0.01 0 1.67
7 INT83416 Binding of OPRK1 and Ntrk1 1 0.02 0 1.45
8 INT82025 Negative_regulation of Binding of Ntrk1 and Ngf 1 0.47 0.64 1.37
9 INT83197 Binding of Ntrk1 and Gdnf 1 0.01 1.05 1.36
10 INT351373 Ngf Positive_regulation of Gene_expression of Ntrk1 1 0.35 0.41 1.18
11 INT351378 Gene_expression of Ngf Positive_regulation of Ntrk1 1 0.35 0.41 1.18
12 INT351377 Gene_expression of Ngf Positive_regulation of Gene_expression of Ntrk1 1 0.35 0.41 1.18
13 INT256041 Binding of Ngfr and Ntrk1 3 0.14 0.9 1.13
14 INT93614 Ngf Positive_regulation of Ntrk1 2 0.52 0.85 1.05
15 INT83415 Binding of Oprm1 and Ntrk1 1 0.01 0 0.96
16 INT297463 Binding of Ntrk1 and Ngf 1 0.10 0.78 0.87
17 INT298295 Runx1 Negative_regulation of Gene_expression of Ntrk1 2 0.38 0.45 0.86
18 INT256045 Binding of BDNF and Ntrk1 3 0.34 0.65 0.83
19 INT78714 Ntrk1 Positive_regulation of Ngf 2 0.50 0.63 0.78
20 INT213726 Binding of Ngfr and Ntrk1 1 0.14 0.96 0.72
21 INT351376 Mir470 Negative_regulation of Ntrk1 1 0.01 1.54 0.7
22 INT221847 Binding of Calca and Ntrk1 1 0.03 0.9 0.65
23 INT79747 Ntf3 Regulation of Positive_regulation of Ntrk1 1 0.35 0 0.6
24 INT98035 Binding of Ntrk1 and Trpv1 1 0.54 0.41 0.57
25 INT242602 Binding of Ntf3 and Ntrk1 1 0.10 0.14 0.57
26 INT245553 Runx1 Positive_regulation of Gene_expression of Ntrk1 2 0.45 1.41 0.52
27 INT242631 Binding of Gfra2 and Ntrk1 1 0.01 0 0.52
28 INT256040 Ngf Regulation of Gene_expression of Ntrk1 1 0.36 0.73 0.5
29 INT118485 CST3 Regulation of CTSH 1 0.36 0 0.49
30 INT137416 Binding of SDC1 and Tnf 1 0.00 1.19 0.47
31 INT242634 Binding of Gfra1 and Ntrk1 1 0.02 0 0.46
32 INT242596 Binding of Ntrk1 and Ret 1 0.12 0 0.46
33 INT256042 Negative_regulation of Musk Negative_regulation of Ntrk1 1 0.08 0.48 0.44
34 INT298284 Runx3 Negative_regulation of Gene_expression of Ntrk1 1 0.26 0.39 0.43
35 INT298263 Pou4f1 Regulation of Gene_expression of Ntrk1 1 0.34 0.61 0.43
36 INT248242 Binding of COL7A1 and SDC1 1 0.00 0.76 0.41
37 INT248236 Binding of FN1 and SDC1 1 0.00 0.76 0.41
38 INT242607 Negative_regulation of Ntrk1 Positive_regulation of Ret 1 0.16 0 0.39
39 INT298266 Gene_expression of Runx1 Positive_regulation of Ntrk1 1 0.28 0.34 0.39
40 INT166247 Ngf Regulation of Ntrk1 1 0.05 0.09 0.38
41 INT223470 Ret Regulation of Ntrk1 1 0.21 0 0.36
42 INT148241 Binding of Kit and Ntrk1 1 0.25 0.44 0.35
43 INT129022 Ngf Positive_regulation of Phosphorylation of Ntrk1 1 0.39 0.37 0.31
44 INT242622 Binding of Bdnf and Ntrk1 1 0.05 0.07 0.29
45 INT245554 Tbx15 Positive_regulation of Gene_expression of Ntrk1 1 0.02 0.65 0.29
46 INT118652 Positive_regulation of Bdnf Positive_regulation of Ntrk1 1 0.31 0.24 0.29
47 INT118654 Bdnf Positive_regulation of Ntrk1 1 0.43 0.24 0.28
48 INT245567 Tbx15 Positive_regulation of Ntrk1 1 0.02 0.9 0.24
49 INT128986 Binding of CST3 and Phdlc1 1 0.01 1.96 0.22
50 INT280473 Binding of Ntrk1 and Ntf4 1 0.00 0.13 0.2
51 INT223477 Binding of Ntrk1 and Ntrk3 2 0.16 0.3 0.19
52 INT266046 Cstb Regulation of Gene_expression of Adrm1 1 0.00 0.7 0.18
53 INT298256 Runx1 Positive_regulation of Negative_regulation of Ntrk1 1 0.30 0.55 0.16
54 INT349861 Gfra1 Negative_regulation of Ntrk1 1 0.01 0.36 0.15
55 INT349852 Gfra2 Negative_regulation of Ntrk1 1 0.27 0.3 0.15
56 INT245566 Runx1 Negative_regulation of Ntrk1 1 0.39 0.65 0.15
57 INT349859 Gfra2 Negative_regulation of Ntrk1 1 0.02 0.3 0.15
58 INT349862 Gfra3 Negative_regulation of Ntrk1 1 0.02 0.3 0.15
59 INT236833 Binding of CD19 and SDC1 1 0.26 0.54 0.15
60 INT201728 Ntrk1 Regulation of Transcription of App 1 0.03 0.39 0.15
61 INT349856 Gfra3 Negative_regulation of Ntrk1 1 0.23 0.3 0.15
62 INT349854 Gfra1 Negative_regulation of Ntrk1 1 0.12 0.36 0.15
63 INT223475 Binding of Ntrk1 and Ntrk2 2 0.22 0.25 0.14
64 INT151925 Bdnf Negative_regulation of Ntrk1 1 0.10 0 0.14
65 INT153620 Binding of Ntrk1 and WNK1 1 0.02 0.85 0.12
66 INT280893 Gene_expression of Runx1 Positive_regulation of Gene_expression of Ntrk1 1 0.33 0.44 0.1
67 INT280492 Ntrk1 Regulation of Protein_catabolism of BDNF 1 0.03 0.14 0.1
68 INT222553 Binding of Sdc1 and Egf 1 0.02 0 0.1
69 INT122927 Ntrk1 Positive_regulation of SPTLC1 1 0.00 0.65 0.09
70 INT280894 Runx1 Positive_regulation of Transcription of Ntrk1 1 0.38 0.36 0.07
71 INT320440 Binding of Adrm1 and Psmb10 1 0.00 0 0.04
72 INT322891 Sox9 Regulation of Transcription of Col2a1 1 0.10 0.12 0.04
73 INT184208 IL1B Negative_regulation of SOX9 1 0.32 0 0.03
74 INT210260 Sox9 Negative_regulation of Cdx2 1 0.20 0 0.03
75 INT121225 Positive_regulation of Ngf Positive_regulation of Ntrk1 2 0.49 0 0
76 INT129874 Binding of CST3 and CTSS 1 0.42 2.45 0
77 INT165187 Positive_regulation of Binding of CST3 and IL18 1 0.03 0.28 0
78 INT320029 Gene_expression of SOX9 Positive_regulation of Gene_expression of COL7A1 1 0.03 0 0
79 INT245726 SOX9 Regulation of SGCG 1 0.00 0.29 0
80 INT321180 Ntrk2 Regulation of Ntrk1 1 0.16 0 0
81 INT208263 Binding of Sdc1 and Msn 1 0.08 0.15 0
82 INT333879 Shc1 Positive_regulation of SOX9 1 0.01 0 0
83 INT225570 Ncoa6 Regulation of Sox9 1 0.16 0.72 0
84 INT345506 Binding of EGFR and FNDC3A 1 0.00 0.08 0
85 INT324305 Binding of CST3 and UMOD 1 0.05 3.22 0
86 INT261840 Binding of Mtap7 and Trpv4 1 0.05 0.12 0
87 INT253945 Adrm1 Negative_regulation of Hdl1 1 0.00 1.18 0
88 INT145556 Binding of CST3 and TNNI3 1 0.25 0.11 0
89 INT324309 Binding of CST3 and GATM 1 0.00 1.6 0
90 INT124074 Binding of Ntrk1 and Ugt1a10 1 0.06 0 0
91 INT165189 Binding of CST3 and IL18 1 0.02 0.28 0
92 INT223478 Binding of Ntrk1 and Dok5 1 0.18 0.17 0
93 INT245735 SOX9 Regulation of COL5A2 1 0.07 0.29 0
94 INT324308 Binding of CST3 and SHROOM3 1 0.04 1.6 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for Sertoli cell development. They are ordered first by their pain relevance and then by number of times they were reported in Sertoli cell development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT50971 Gene_expression of Ntrk1 180 0.75 73.52 62.28
2 INT50970 Positive_regulation of Ntrk1 51 0.57 29.38 22.83
3 INT56769 Gene_expression of Ntrk1 36 0.77 15.79 20.75
4 INT50972 Negative_regulation of Ntrk1 39 0.51 32.22 17.29
5 INT108384 Binding of Ntrk1 28 0.39 10.73 9.09
6 INT50973 Negative_regulation of Gene_expression of Ntrk1 22 0.56 11.12 7.38
7 INT129020 Phosphorylation of Ntrk1 17 0.80 5.97 6.37
8 INT79737 Positive_regulation of Ntrk1 12 0.49 3.98 6.24
9 INT677 Positive_regulation of CST3 20 0.67 17.47 6
10 INT87470 Gene_expression of SDC1 27 0.78 24.86 5.81
11 INT14501 Gene_expression of CST3 28 0.75 25.77 5.16
12 INT78981 Regulation of Ntrk1 6 0.44 3.89 4.52
13 INT81750 Regulation of Ntrk1 13 0.52 6.03 4.37
14 INT79736 Negative_regulation of Ntrk1 11 0.57 2.31 4.14
15 INT56768 Positive_regulation of Gene_expression of Ntrk1 5 0.67 3.91 3.83
16 INT83411 Binding of Ntrk1 6 0.19 3.7 3.74
17 INT212563 Gene_expression of Adrm1 26 0.13 11.46 3.58
18 INT156189 Positive_regulation of Gene_expression of Ntrk1 11 0.49 2.81 2.89
19 INT62610 Phosphorylation of Ntrk1 5 0.56 1.64 2.68
20 INT221762 Regulation of Gene_expression of Adrm1 4 0.07 4.45 2.42
21 INT640 Regulation of CST3 9 0.60 4.04 2.26
22 INT14500 Positive_regulation of Gene_expression of CST3 9 0.67 7.46 1.87
23 INT107477 Positive_regulation of Phosphorylation of Ntrk1 3 0.30 0.88 1.86
24 INT223447 Regulation of Gene_expression of Ntrk1 7 0.34 1.29 1.82
25 INT183276 Negative_regulation of Adrm1 10 0.04 7.25 1.74
26 INT60975 Localization of CST3 6 0.78 2.4 1.58
27 INT129017 Negative_regulation of Phosphorylation of Ntrk1 3 0.41 1.5 1.42
28 INT245532 Negative_regulation of Positive_regulation of Ntrk1 2 0.34 1.56 1.34
29 INT214574 Positive_regulation of SDC1 4 0.32 3.24 1.28
30 INT93612 Transcription of Ntrk1 2 0.52 1.31 1.26
31 INT679 Negative_regulation of CST3 7 0.57 4.63 1.22
32 INT134663 Gene_expression of SOX9 40 0.75 9.07 1.2
33 INT93610 Negative_regulation of Gene_expression of Ntrk1 2 0.41 0.84 1.15
34 INT124069 Localization of Ntrk1 9 0.59 3.32 1.13
35 INT36064 Binding of CST3 14 0.47 16.38 1.12
36 INT106746 Gene_expression of Mtap7 1 0.39 2.09 0.95
37 INT166715 Gene_expression of Sox9 16 0.65 6.39 0.92
38 INT201635 Positive_regulation of Positive_regulation of Ntrk1 3 0.40 1.15 0.85
39 INT90363 Regulation of SDC1 3 0.45 3.68 0.83
40 INT90364 Positive_regulation of Gene_expression of SDC1 3 0.70 2.59 0.83
41 INT145306 Gene_expression of Sox9 5 0.54 2.47 0.8
42 INT93609 Positive_regulation of Transcription of Ntrk1 1 0.45 0.86 0.69
43 INT62608 Negative_regulation of Phosphorylation of Ntrk1 1 0.40 0.24 0.69
44 INT109603 Positive_regulation of Localization of CST3 1 0.45 0.61 0.67
45 INT78183 Negative_regulation of Adrm1 8 0.09 3.4 0.65
46 INT212562 Positive_regulation of Adrm1 16 0.10 5.08 0.62
47 INT90362 Negative_regulation of Gene_expression of SDC1 3 0.59 2.88 0.59
48 INT93613 Regulation of Gene_expression of Ntrk1 1 0.60 0.8 0.59
49 INT184222 Negative_regulation of SOX9 7 0.41 2.68 0.58
50 INT157103 Transcription of SOX9 6 0.59 1.2 0.58
51 INT118730 Regulation of Transcription of Ntrk1 1 0.43 0.45 0.57
52 INT157104 Positive_regulation of SOX9 6 0.66 1.66 0.52
53 INT157105 Positive_regulation of Transcription of SOX9 4 0.58 0.88 0.51
54 INT105210 Positive_regulation of Adrm1 7 0.06 4.09 0.5
55 INT145304 Regulation of Gene_expression of Sox9 1 0.43 1.04 0.46
56 INT97723 Negative_regulation of Regulation of Ntrk1 1 0.37 0.52 0.45
57 INT250468 Positive_regulation of Gene_expression of Adrm1 2 0.04 2.26 0.44
58 INT98419 Positive_regulation of Mtap7 3 0.38 2.66 0.41
59 INT297454 Negative_regulation of Negative_regulation of Ntrk1 1 0.09 0.23 0.41
60 INT137415 Regulation of Gene_expression of SDC1 2 0.02 2.53 0.4
61 INT242553 Positive_regulation of Negative_regulation of Ntrk1 1 0.21 0 0.39
62 INT212565 Regulation of Adrm1 3 0.04 2.41 0.36
63 INT156280 Gene_expression of Sdc1 6 0.43 0.55 0.34
64 INT212564 Negative_regulation of Gene_expression of Adrm1 3 0.05 1.7 0.34
65 INT148814 Localization of Ntrk1 1 0.78 0.16 0.34
66 INT109604 Negative_regulation of Localization of CST3 1 0.41 0.31 0.31
67 INT244625 Negative_regulation of Localization of Ntrk1 1 0.04 0.56 0.28
68 INT90361 Localization of SDC1 2 0.62 0.86 0.24
69 INT156282 Positive_regulation of Sdc1 1 0.50 0.17 0.24
70 INT145303 Regulation of Sox9 2 0.28 0.71 0.22
71 INT245763 Regulation of SOX9 4 0.43 1.68 0.21
72 INT280460 Positive_regulation of Localization of Ntrk1 2 0.11 0.32 0.21
73 INT20608 Positive_regulation of Regulation of CST3 1 0.01 1.23 0.21
74 INT134662 Positive_regulation of Gene_expression of SOX9 9 0.48 1.69 0.19
75 INT250467 Localization of Adrm1 2 0.06 0.97 0.19
76 INT250469 Positive_regulation of Localization of Adrm1 2 0.04 0.97 0.19
77 INT186140 Gene_expression of Adrm1 2 0.06 1.01 0.18
78 INT242558 Transcription of Ntrk1 2 0.37 0.66 0.17
79 INT222655 Binding of Sdc1 3 0.05 0.64 0.12
80 INT211949 Negative_regulation of Sox9 1 0.31 0.83 0.12
81 INT156281 Positive_regulation of Gene_expression of Sdc1 1 0.33 0.1 0.11
82 INT242544 Positive_regulation of Transcription of Ntrk1 1 0.29 0.3 0.1
83 INT212172 Binding of Adrm1 7 0.36 1.38 0.09
84 INT184220 Negative_regulation of Gene_expression of SOX9 4 0.36 0.58 0.09
85 INT314778 Regulation of Binding of CST3 1 0.26 1.5 0.09
86 INT678 Regulation of Negative_regulation of CST3 1 0.39 0.09 0.09
87 INT41924 Phosphorylation of CST3 1 0.57 0.23 0.09
88 INT211948 Regulation of Gene_expression of Sox9 2 0.33 0.94 0.08
89 INT39981 Positive_regulation of Binding of CST3 1 0.43 0.71 0.08
90 INT212476 Binding of FNDC3A 1 0.03 0.06 0.07
91 INT210242 Positive_regulation of Sox9 3 0.43 0.35 0.06
92 INT211939 Regulation of Sox9 1 0.33 0.35 0.06
93 INT215445 Transcription of Adrm1 2 0.08 0.08 0.05
94 INT225365 Binding of Sox9 2 0.28 0.48 0.03
95 INT145302 Positive_regulation of Sox9 2 0.48 1.42 0.03
96 INT288241 Regulation of Gene_expression of CST3 1 0.44 0.28 0.03
97 INT162339 Regulation of Gene_expression of SOX9 4 0.32 0.42 0
98 INT245757 Localization of SOX9 4 0.62 0.8 0
99 INT211945 Negative_regulation of Gene_expression of Sox9 3 0.44 0.63 0
100 INT94755 Binding of Mtap7 1 0.31 0 0
101 INT322883 Regulation of Transcription of Sox9 1 0.43 0.18 0
102 INT155405 Negative_regulation of Positive_regulation of Ntrk1 1 0.09 0.15 0
103 INT351372 Regulation of Localization of Ntrk1 1 0.34 0.92 0
104 INT130135 Regulation of Localization of CST3 1 0.26 0 0
105 INT356397 Negative_regulation of SDC1 1 0.01 2.75 0
106 INT267790 Binding of Adrm1 1 0.07 0 0
107 INT211943 Transcription of Sox9 1 0.50 0.3 0
108 INT323815 Negative_regulation of Transcription of SOX9 1 0.41 0.18 0
109 INT214927 Binding of SDC1 1 0.11 0 0
110 INT317587 Negative_regulation of Negative_regulation of Adrm1 1 0.03 0 0
111 INT322886 Transcription of Sox9 1 0.50 0.25 0
112 INT145307 Positive_regulation of Positive_regulation of Sox9 1 0.48 0.07 0
113 INT314777 Negative_regulation of Gene_expression of CST3 1 0.41 1.32 0
114 INT245752 Positive_regulation of Binding of SOX9 1 0.41 0.48 0
115 INT317588 Regulation of Adrm1 1 0.05 0 0
116 INT92060 Localization of Mtap7 1 0.22 0.07 0
117 INT92061 Phosphorylation of Mtap7 1 0.20 0.07 0
118 INT245765 Binding of SOX9 1 0.31 0.87 0
119 INT312245 Positive_regulation of Localization of SOX9 1 0.10 0 0
120 INT324333 Transcription of CST3 1 0.67 0.2 0
121 INT352010 Protein_catabolism of Sox9 1 0.22 0.07 0
122 INT308349 Positive_regulation of Gene_expression of Sox9 1 0.40 0.69 0
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