GO:0060021

From wiki-pain
Jump to: navigation, search
Name palate development
Categary Process
Go Slim No
Go Link GO:0060021
Unique Molecular Interactions 511
Total Molecular Interactions 593
Total Single Events 4576
Pain Genes Associated 66

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for palate development. They are ordered first by their pain relevance and then by number of times they were reported for palate development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT311914 Il1 Negative_regulation of Gene_expression of Col2a1 1 0.01 1.94 1.23
2 INT281373 Tcf21 Regulation of Fig4 1 0.03 0.67 1.2
3 INT281379 Tcf21 Regulation of FSCN1 1 0.01 0.66 1.19
4 INT125284 FSCN1 Positive_regulation of Positive_regulation of EPHB2 1 0.04 0.4 1.14
5 INT107938 POMC Positive_regulation of Gene_expression of TGFBR2 1 0.42 1.09 1.07
6 INT221 Chd7 Negative_regulation of Th 1 0.02 0 1.04
7 INT204551 Binding of Col2a1 and Positive_regulation of Cia1 1 0.03 1.74 1.03
8 INT75486 Binding of Tgfbr1 and Tgfbr2 1 0.10 1.94 1.02
9 INT154236 Binding of TBX3 and Ugt2b7 1 0.41 0.74 1
10 INT316128 TCF21 Negative_regulation of Gene_expression of HLA-DRA 1 0.07 0.13 0.99
11 INT141276 Negative_regulation of Il18 Negative_regulation of Gene_expression of Hand2 1 0.25 0.8 0.92
12 INT169477 TGFB3 Positive_regulation of Spink3 1 0.02 1.83 0.89
13 INT74872 Igh-Dex Positive_regulation of Chd7 1 0.01 0.5 0.89
14 INT140985 Gli3 Regulation of Ihh 1 0.29 0.85 0.85
15 INT278690 LEF1 Negative_regulation of Gene_expression of IK 1 0.00 0.66 0.83
16 INT328501 Sumo1 Negative_regulation of Gene_expression of Pglyrp1 1 0.00 1.54 0.83
17 INT63594 Snai1 Negative_regulation of Binding of Ugt1a2 1 0.05 0.32 0.82
18 INT63596 Snai1 Negative_regulation of ITS 1 0.00 0.31 0.81
19 INT107937 POMC Regulation of Gene_expression of TGFBR2 1 0.28 0.82 0.81
20 INT86150 Inhba Positive_regulation of Gene_expression of Calca 1 0.09 0.61 0.81
21 INT278697 LEF1 Negative_regulation of STAT6 1 0.00 0.44 0.78
22 INT161951 Positive_regulation of TGFBR1 Positive_regulation of Gene_expression of Ngf 1 0.27 0.99 0.76
23 INT161945 TGFB2 Positive_regulation of TGFBR1 1 0.08 0.99 0.76
24 INT314203 Nos2 Positive_regulation of Gli3 1 0.19 1.27 0.73
25 INT161950 TGFBR1 Negative_regulation of Localization of Ngf 1 0.23 1.01 0.72
26 INT207540 Tfap2a Regulation of Oprm1 1 0.13 0.06 0.7
27 INT222811 Binding of Hand2 and TH1L 4 0.03 8.26 0.69
28 INT135207 Gmeb1 Regulation of Gene_expression of Tfap2a 1 0.07 0.48 0.69
29 INT135206 Ighen Regulation of Gene_expression of Tfap2a 1 0.06 0.48 0.69
30 INT135202 Tfap2a Regulation of Gene_expression of Ighen 1 0.06 0.48 0.69
31 INT135213 Tfap2a Regulation of Gene_expression of Nfkb1 1 0.02 0.48 0.69
32 INT135211 Nfkb1 Regulation of Gene_expression of Tfap2a 1 0.02 0.48 0.69
33 INT135204 Tfap2a Regulation of Gene_expression of Gmeb1 1 0.10 0.48 0.69
34 INT68561 Binding of Gli3 and Ust 1 0.01 0.68 0.68
35 INT207543 Tfap2a Regulation of Qsox1 1 0.04 0.06 0.67
36 INT83804 Binding of EPHB3 and DRGX 1 0.00 0.62 0.62
37 INT222246 Binding of Ccr2 and Tcf21 1 0.29 0.67 0.55
38 INT222249 Positive_regulation of Binding of Ccr2 and Tcf21 1 0.39 0.67 0.55
39 INT281124 Tcf21 Positive_regulation of Binding of Ddc 1 0.04 1.21 0.54
40 INT281129 Tcf21 Positive_regulation of Binding of Cd4 1 0.04 1.21 0.54
41 INT202043 MMP13 Regulation of Protein_catabolism of COL2A1 1 0.01 0.54 0.54
42 INT281152 Tcf21 Positive_regulation of Binding of ITIH4 1 0.03 1.21 0.54
43 INT281131 Tcf21 Positive_regulation of Rent1 1 0.00 1.19 0.53
44 INT120383 PRKCD Positive_regulation of Localization of EPHB2 1 0.29 0.42 0.52
45 INT281374 Tcf21 Positive_regulation of Gene_expression of Sds 1 0.03 0 0.51
46 INT302644 ARSA Positive_regulation of Gene_expression of TGFBR1 1 0.04 0.29 0.51
47 INT302647 ARSA Positive_regulation of TGFBR1 1 0.03 0.29 0.51
48 INT244028 Positive_regulation of Binding of Cacnb3 and Tfap2a 1 0.01 0.24 0.49
49 INT244037 Positive_regulation of Binding of Prkaca and Tfap2a 1 0.01 0.24 0.49
50 INT244000 Positive_regulation of Binding of Tfap2a and Dnm1 1 0.04 0.24 0.49
51 INT244035 Binding of Prkaca and Tfap2a 1 0.01 0.24 0.49
52 INT243997 Binding of Tfap2a and Dnm1 1 0.03 0.24 0.49
53 INT244060 Binding of Cacnb3 and Tfap2a 1 0.00 0.24 0.49
54 INT108329 EGF Positive_regulation of Phosphorylation of EPHB2 4 0.48 3.96 0.48
55 INT338426 Binding of Hand1 and Hand2 2 0.06 2 0.46
56 INT275549 Il10 Positive_regulation of Localization of Hand2 1 0.01 1.3 0.46
57 INT20761 INHBA Regulation of Localization of GNRH1 1 0.02 0 0.46
58 INT275550 Hand1 Positive_regulation of Localization of Hand2 1 0.00 1.29 0.46
59 INT169478 TGFB3 Positive_regulation of Tgfa 1 0.01 0.9 0.44
60 INT169466 TGFB3 Positive_regulation of HRAS 1 0.03 0.89 0.43
61 INT278950 MAPK8 Negative_regulation of Localization of EPHB2 1 0.25 0.47 0.43
62 INT278964 MAPK14 Negative_regulation of Localization of EPHB2 1 0.15 0.47 0.43
63 INT169465 TGFB3 Positive_regulation of MTG1 1 0.03 0.89 0.43
64 INT75488 Binding of TGFB1 and Tgfbr1 1 0.23 0.78 0.41
65 INT75489 Binding of SGCG and Tgfbr2 1 0.23 0.83 0.41
66 INT75487 Binding of TGFB1 and Tgfbr2 1 0.31 0.83 0.41
67 INT312122 ELANE Positive_regulation of Protein_catabolism of COL2A1 1 0.05 0.65 0.39
68 INT342783 Prdm16 Positive_regulation of Gene_expression of Gal 1 0.02 0.72 0.37
69 INT340609 Bdnf Regulation of Gene_expression of Wnt3a 1 0.53 0.31 0.36
70 INT305853 Polk Regulation of Gene_expression of Hand2 1 0.12 0.93 0.35
71 INT168202 Msx1 Negative_regulation of Gene_expression of Mc1r 1 0.21 0.49 0.35
72 INT254344 Binding of Col2a1 and Ncoa5 1 0.00 0.98 0.35
73 INT300751 Binding of IGHE and Hand2 1 0.04 0 0.34
74 INT301054 Tfap2a Regulation of Gene_expression of Faslg 1 0.00 1.23 0.34
75 INT266806 Hand2 Regulation of Gene_expression of IL10 1 0.00 1.23 0.32
76 INT241139 Ighg1 Positive_regulation of Hand2 1 0.06 0.65 0.32
77 INT181435 Binding of Ccr2 and Hand2 1 0.17 1.81 0.32
78 INT181433 Hand2 Regulation of Gene_expression of Ccl2 1 0.12 0.68 0.32
79 INT222251 Negative_regulation of Binding of Cxcl10 and Tcf21 1 0.23 0.34 0.32
80 INT266804 Hand2 Regulation of Gene_expression of IL13 1 0.00 1.23 0.32
81 INT266805 Hand2 Regulation of Gene_expression of IL4 1 0.00 1.23 0.32
82 INT222247 Binding of Cxcl10 and Tcf21 1 0.20 0.34 0.32
83 INT253073 Il4 Positive_regulation of Hand2 1 0.10 0.59 0.31
84 INT300742 Stat6 Regulation of Hand2 1 0.01 0.06 0.3
85 INT300752 GATA3 Regulation of Hand2 1 0.01 0.06 0.3
86 INT166165 Binding of TGFB3 and Bmp2 1 0.00 0 0.3
87 INT93988 Rab8a Regulation of Hand2 1 0.09 0.78 0.3
88 INT281127 Tcf21 Positive_regulation of Gene_expression of Cxcr4 1 0.08 0.42 0.3
89 INT264523 PTGDS Positive_regulation of Gene_expression of COL2A1 1 0.03 1.24 0.3
90 INT220194 PTGER2 Negative_regulation of COL2A1 1 0.26 0.55 0.29
91 INT328224 Col2a1 Positive_regulation of Gene_expression of Mmp13 1 0.04 0.8 0.29
92 INT328500 Sumo1 Positive_regulation of Negative_regulation of Cebpz 1 0.11 1.06 0.29
93 INT137023 Gene_expression of SMAD2 Negative_regulation of Gene_expression of Acta2 1 0.00 0.43 0.29
94 INT181442 Ccl2 Positive_regulation of Localization of Hand2 1 0.26 0.63 0.29
95 INT75056 Binding of MC1R and Msx1 1 0.00 0.17 0.29
96 INT185076 Bpifa2 Positive_regulation of Hand2 1 0.16 0.36 0.28
97 INT278209 Ciita Regulation of Hand2 1 0.36 1.53 0.28
98 INT194821 MAPK1 Regulation of Hand2 1 0.03 1.27 0.28
99 INT18499 Binding of SUMO1 and SEC1 1 0.12 0 0.28
100 INT162599 Wnt5a Regulation of Gene_expression of IL4I1 1 0.00 0.1 0.28
101 INT278216 Ciita Regulation of Gene_expression of Hand2 1 0.36 1.53 0.28
102 INT246442 Hand2 Positive_regulation of Gene_expression of Cd79a 1 0.03 0.78 0.27
103 INT328499 Binding of Cebpz and Sumo1 1 0.08 0.84 0.27
104 INT305849 Polk Positive_regulation of Gene_expression of Hand2 1 0.08 0.76 0.27
105 INT311918 Insrr Negative_regulation of Tgfbr1 1 0.00 0.87 0.26
106 INT311902 Acvrl1 Negative_regulation of Tgfbr1 1 0.13 0.87 0.26
107 INT226537 Hand2 Positive_regulation of IL22 1 0.02 0.86 0.26
108 INT168203 Binding of Mc1r and Msx1 1 0.19 0.64 0.25
109 INT311911 Tgfbr1 Positive_regulation of Gene_expression of Mmp13 1 0.10 0.55 0.23
110 INT115148 PPARG Negative_regulation of Gene_expression of INSIG2 1 0.01 0.34 0.21
111 INT195212 Binding of CCR4 and Hand2 1 0.03 0.46 0.21
112 INT75057 Binding of POMC and Msx1 2 0.39 0.6 0.2
113 INT265603 Msc Positive_regulation of Gene_expression of Il6 1 0.16 1.79 0.2
114 INT60347 COL2A1 Positive_regulation of Gene_expression of Hras 1 0.05 0.92 0.2
115 INT226511 Gene_expression of Il25 Positive_regulation of Gene_expression of Hand2 1 0.01 0.95 0.2
116 INT226514 BTPs Negative_regulation of Gene_expression of Hand2 1 0.03 0.22 0.2
117 INT338767 Positive_regulation of Binding of Hand1 and Hand2 1 0.07 0.5 0.2
118 INT226510 BTPs Negative_regulation of Hand2 1 0.03 0.22 0.2
119 INT175464 Hand2 Positive_regulation of Gene_expression of Sftpd 1 0.19 1.05 0.2
120 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19
121 INT14869 Binding of EGF and TGFB3 1 0.14 0.69 0.19
122 INT153460 Inhba Positive_regulation of Gene_expression of Ctgf 1 0.77 1.14 0.19
123 INT228737 Rae1 Negative_regulation of Hand2 1 0.08 1.07 0.19
124 INT220190 PTGER2 Regulation of COL2A1 1 0.32 0.92 0.18
125 INT222025 Gpx3 Regulation of EPHB2 1 0.01 1.41 0.18
126 INT316748 IL18 Positive_regulation of Regulation of Hand2 1 0.14 1.11 0.18
127 INT220191 Binding of COL2A1 and PTGER2 1 0.22 0.35 0.18
128 INT329843 Il4 Regulation of Hand2 1 0.04 0.87 0.18
129 INT181457 Binding of CCL16 and Hand2 1 0.04 0.92 0.17
130 INT333449 Binding of SMAD2 and SMAD4 1 0.23 0 0.17
131 INT346305 Binding of ELANE and Col2a1 1 0.00 0.98 0.17
132 INT222877 Chrm2 Negative_regulation of EPHB2 1 0.05 0.66 0.17
133 INT291354 CXCL12 Positive_regulation of EPHB2 1 0.42 2.02 0.16
134 INT333447 Binding of SMAD2 and RXRA 1 0.04 0 0.16
135 INT171871 Binding of FAS and Sumo1 1 0.02 1.43 0.16
136 INT171870 Binding of Ltbr and Sumo1 1 0.00 1.44 0.16
137 INT294766 Cerk Regulation of Gene_expression of Hand2 1 0.13 0.32 0.15
138 INT97547 KITLG Negative_regulation of Msx1 1 0.00 0.08 0.15
139 INT97542 Pomc Negative_regulation of Msx1 1 0.13 0.07 0.15
140 INT316479 Il6 Positive_regulation of Snai1 1 0.24 0.33 0.15
141 INT350713 MIR219-1 Negative_regulation of Pdgfra 1 0.00 0.4 0.15
142 INT97545 Gtf3a Negative_regulation of Msx1 1 0.02 0.08 0.15
143 INT347012 Hand2 Positive_regulation of Il4 1 0.01 0 0.14
144 INT336337 Glp2r Positive_regulation of Gene_expression of Col2a1 1 0.01 0.7 0.14
145 INT340608 Binding of Creb1 and Wnt3a 1 0.30 0.24 0.14
146 INT95103 TGFBR2 Positive_regulation of CD34 1 0.11 0.61 0.14
147 INT287890 THEMIS Regulation of Gene_expression of EPHB2 1 0.00 0.87 0.14
148 INT293867 Binding of COL2A1 and MEFV 1 0.01 0.52 0.14
149 INT95104 TGFBR2 Positive_regulation of BCL2 1 0.08 0.61 0.14
150 INT347015 Hand2 Regulation of Cd86 1 0.06 0 0.14
151 INT294764 Binding of Hand2 and Cerk 1 0.17 0.31 0.14
152 INT287883 FOS Regulation of Gene_expression of EPHB2 1 0.01 0.87 0.14
153 INT314852 Binding of Cdkn2a and Tgfbr3 1 0.28 1.15 0.14
154 INT235546 Stat6 Positive_regulation of Positive_regulation of Hand2 1 0.02 0.9 0.14
155 INT220213 Mmp13 Regulation of Protein_catabolism of COL2A1 1 0.49 0.29 0.14
156 INT314859 Binding of Cdkn2b and Tgfbr3 1 0.33 1.16 0.14
157 INT347018 Cd80 Regulation of Hand2 1 0.03 0.05 0.13
158 INT333652 Binding of Ccr5 and Msc 1 0.10 0.07 0.13
159 INT323430 Binding of Vhl and Osr1 1 0.02 0.78 0.13
160 INT326249 Prkcg Positive_regulation of EPHB2 1 0.06 0.63 0.13
161 INT347007 Cd86 Regulation of Hand2 1 0.06 0.05 0.13
162 INT326252 EPHB2 Positive_regulation of ras 1 0.03 0.62 0.13
163 INT291349 CXCR4 Positive_regulation of EPHB2 1 0.42 1.87 0.13
164 INT287884 WNT5A Positive_regulation of THEMIS 1 0.00 0.08 0.13
165 INT108330 EGF Negative_regulation of EPHB2 1 0.41 1.15 0.13
166 INT323434 Osr1 Regulation of Hif1a 1 0.01 0.79 0.13
167 INT333653 Binding of Msc and Tg(CAG-EGFP)D4Nagy 1 0.01 0.07 0.13
168 INT323435 Binding of Osr1 and Gtf3a 1 0.00 0.78 0.13
169 INT323433 Osr1 Regulation of Protein_catabolism of Hif1a 1 0.01 0.8 0.13
170 INT262197 Nr1i2 Positive_regulation of Insig1 2 0.23 0 0.12
171 INT296080 TGFB1 Regulation of Hand2 1 0.01 1 0.12
172 INT294760 Cerk Positive_regulation of Hand2 1 0.23 0.16 0.12
173 INT214150 Binding of Mc3r and Msx1 1 0.03 0.5 0.12
174 INT172976 Mras Regulation of Gene_expression of Smad4 1 0.00 0.83 0.12
175 INT253077 Prok2 Regulation of Gene_expression of Hand2 1 0.10 0.11 0.12
176 INT294758 Regulation of Cerk Positive_regulation of Hand2 1 0.21 0.16 0.12
177 INT281192 Casr Positive_regulation of Insig1 1 0.23 0 0.12
178 INT228746 Hspa9 Negative_regulation of Positive_regulation of Hand2 1 0.11 0.31 0.11
179 INT326974 BMP2 Positive_regulation of Gene_expression of COL2A1 1 0.07 0.27 0.11
180 INT228760 Rae1 Negative_regulation of Positive_regulation of Hand2 1 0.08 0.31 0.11
181 INT175463 Sftpd Negative_regulation of Gene_expression of Hand2 1 0.17 0.96 0.11
182 INT214152 Binding of Mc4r and Msx1 1 0.03 0.24 0.11
183 INT316823 Sparc Positive_regulation of Phosphorylation of Smad2 1 0.44 0.49 0.1
184 INT215245 Binding of Myo1f and Chd7 1 0.00 0.64 0.1
185 INT233510 Wnt5a Positive_regulation of Gene_expression of Il12a 1 0.03 0.33 0.1
186 INT224021 PIK3CG Negative_regulation of EPHB2 1 0.03 0.5 0.09
187 INT263495 Hand1 Regulation of Localization of Hand2 1 0.12 0.5 0.09
188 INT263496 Hand2 Regulation of Localization of Hand1 1 0.12 0.5 0.09
189 INT239559 MSC Regulation of Gene_expression of BDNF 1 0.05 1 0.09
190 INT220195 PTGER2 Negative_regulation of Localization of COL2A1 1 0.26 0.51 0.09
191 INT214168 Msx1 Positive_regulation of Gene_expression of DST 1 0.00 0.13 0.09
192 INT224020 MAPK1 Negative_regulation of EPHB2 1 0.08 0.56 0.09
193 INT346304 Col2a1 Positive_regulation of Localization of PTGER2 1 0.00 0.18 0.09
194 INT201349 Binding of Hand2 and Il4 1 0.17 0.67 0.09
195 INT211960 Wnt5a Positive_regulation of Car2 1 0.13 0.38 0.08
196 INT238628 Mef2c Regulation of Gene_expression of Arc 1 0.09 0.16 0.08
197 INT270464 Binding of Shh and Smo 1 0.07 1.3 0.08
198 INT311917 Gene_expression of Tgfbr1 Positive_regulation of Gene_expression of Mmp13 1 0.10 0.31 0.08
199 INT238625 Mef2c Regulation of Gene_expression of Syngap1 1 0.10 0.16 0.08
200 INT288374 Binding of MLANA and Msx1 1 0.09 0 0.08

Single Events

The table below shows the top 100 pain related interactions that have been reported for palate development. They are ordered first by their pain relevance and then by number of times they were reported in palate development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05
2 INT11659 Gene_expression of COL2A1 164 0.78 78.49 22.58
3 INT84732 Positive_regulation of Hand2 81 0.69 62.07 22
4 INT112017 Regulation of Hand2 77 0.36 62.23 18.04
5 INT173505 Localization of Hand2 63 0.57 45.32 13.66
6 INT37618 Gene_expression of Col2a1 50 0.70 33.88 11.58
7 INT215353 Gene_expression of Tcf21 16 0.59 9.71 9.49
8 INT54834 Gene_expression of Col2a1 48 0.72 13.5 9.41
9 INT130731 Protein_catabolism of COL2A1 47 0.96 21.86 9.28
10 INT132586 Negative_regulation of Hand2 40 0.30 26.58 9.28
11 INT93045 Negative_regulation of Gene_expression of Hand2 31 0.43 25.26 9.24
12 INT340600 Gene_expression of Wnt3a 1 0.68 2.14 9.14
13 INT1223 Negative_regulation of Snai1 15 0.38 2.05 8.46
14 INT87650 Positive_regulation of EPHB2 49 0.67 22.77 8.25
15 INT108336 Phosphorylation of EPHB2 41 0.80 22.25 8.21
16 INT39301 Gene_expression of Chd7 50 0.26 27.06 8.13
17 INT20914 Positive_regulation of Snai1 13 0.41 3.41 7.69
18 INT93046 Positive_regulation of Gene_expression of Hand2 27 0.47 24.54 7.01
19 INT125143 Gene_expression of EPHB2 40 0.71 13.27 6.97
20 INT28122 Gene_expression of MSC 111 0.58 26.83 6.57
21 INT127112 Phosphorylation of Smad2 19 0.80 11.01 5.36
22 INT68559 Negative_regulation of Gli3 5 0.37 4.56 4.93
23 INT72834 Negative_regulation of Tcf21 10 0.58 5.8 4.84
24 INT20552 Negative_regulation of Gene_expression of COL2A1 29 0.56 11.92 4.81
25 INT108342 Negative_regulation of EPHB2 18 0.57 9.48 4.46
26 INT94466 Regulation of Gene_expression of Hand2 14 0.28 7.97 4.46
27 INT37912 Negative_regulation of Chd7 10 0.26 5.84 4.46
28 INT217742 Positive_regulation of Gene_expression of COL2A1 20 0.67 9.76 4.23
29 INT38066 Binding of MSC 14 0.41 5.28 4.12
30 INT156131 Binding of Hand2 14 0.25 10.35 3.99
31 INT124815 Binding of Col2a1 9 0.37 10.27 3.93
32 INT75485 Gene_expression of Tgfbr2 10 0.57 10.98 3.76
33 INT22566 Positive_regulation of Tcf21 8 0.65 3.06 3.75
34 INT340603 Regulation of Gene_expression of Wnt3a 1 0.54 0.49 3.75
35 INT9144 Localization of MSC 18 0.56 10.17 3.69
36 INT64919 Gene_expression of Prdm16 6 0.75 11.63 3.5
37 INT53021 Positive_regulation of COL2A1 29 0.55 27.75 3.47
38 INT117836 Gene_expression of EPHB3 13 0.29 0.62 3.44
39 INT130729 Negative_regulation of Protein_catabolism of COL2A1 15 0.42 7.59 3.35
40 INT127111 Regulation of Inhba 5 0.60 2.85 3.28
41 INT39867 Binding of Col2a1 9 0.35 7.65 3.18
42 INT54832 Negative_regulation of Gene_expression of Col2a1 6 0.50 2.53 3.16
43 INT75484 Gene_expression of Tgfbr1 21 0.64 13.36 3.15
44 INT340595 Positive_regulation of Gene_expression of Wnt3a 1 0.61 0.86 3.11
45 INT171884 Positive_regulation of Gene_expression of Col2a1 11 0.23 8.04 3.02
46 INT14872 Gene_expression of TGFB3 15 0.55 12.45 2.96
47 INT37715 Positive_regulation of MSC 34 0.48 10.52 2.92
48 INT108338 Positive_regulation of Phosphorylation of EPHB2 13 0.67 5.42 2.92
49 INT281367 Regulation of Gene_expression of Tcf21 1 0.09 1.39 2.89
50 INT132773 Negative_regulation of Acvr2b 3 0.41 1.55 2.87
51 INT95105 Gene_expression of TGFBR2 15 0.64 16.36 2.74
52 INT1225 Regulation of Snai1 10 0.30 1.05 2.72
53 INT20551 Negative_regulation of COL2A1 31 0.55 21.98 2.66
54 INT96693 Binding of COL2A1 45 0.46 37.11 2.61
55 INT77852 Binding of Chd7 8 0.31 4.1 2.51
56 INT127113 Positive_regulation of Phosphorylation of Smad2 1 0.68 2.38 2.51
57 INT127108 Gene_expression of Inhba 12 0.65 3.21 2.48
58 INT126581 Positive_regulation of Gli3 6 0.35 1.59 2.48
59 INT281369 Negative_regulation of Gene_expression of Tcf21 1 0.08 1.4 2.44
60 INT32920 Gene_expression of Msx1 19 0.71 4.24 2.42
61 INT86147 Positive_regulation of Inhba 8 0.63 1.94 2.39
62 INT269217 Gene_expression of SNAI1 81 0.76 80.49 2.26
63 INT194504 Gene_expression of Smad2 27 0.65 7.45 2.25
64 INT55090 Positive_regulation of Wnt7a 13 0.37 2.25 2.2
65 INT116077 Positive_regulation of Positive_regulation of EPHB2 4 0.67 2.32 2.13
66 INT126374 Gene_expression of Gli3 6 0.77 3.67 2.02
67 INT90004 Gene_expression of TCF21 4 0.65 2.48 2.02
68 INT144973 Gene_expression of Shh 9 0.77 4.32 1.96
69 INT80798 Positive_regulation of Chd7 16 0.14 7.95 1.95
70 INT129239 Positive_regulation of Positive_regulation of Hand2 5 0.43 2.81 1.93
71 INT107178 Gene_expression of Smad4 12 0.65 9.85 1.92
72 INT173641 Regulation of MSC 13 0.39 2.85 1.82
73 INT164407 Negative_regulation of Gene_expression of Col2a1 6 0.39 4 1.78
74 INT208561 Gene_expression of Shh 51 0.78 9.57 1.77
75 INT316162 Localization of TCF21 1 0.18 0.28 1.71
76 INT32024 Positive_regulation of Positive_regulation of Snai1 2 0.25 0.32 1.7
77 INT220992 Protein_catabolism of Col2a1 8 0.40 5.55 1.64
78 INT55302 Binding of Snai1 2 0.31 1.94 1.63
79 INT127110 Transcription of Inhba 3 0.58 1.44 1.59
80 INT28123 Positive_regulation of Gene_expression of MSC 17 0.43 4.02 1.54
81 INT278715 Gene_expression of LEF1 10 0.33 5.43 1.54
82 INT164410 Negative_regulation of Col2a1 4 0.39 3.75 1.53
83 INT127115 Regulation of Phosphorylation of Smad2 1 0.60 1.74 1.53
84 INT18503 Binding of SUMO1 7 0.27 6.21 1.48
85 INT100672 Transcription of Hand2 9 0.42 2.84 1.47
86 INT278727 Negative_regulation of Gene_expression of LEF1 3 0.11 1.59 1.47
87 INT254330 Regulation of Msc 10 0.16 7.59 1.46
88 INT140245 Binding of Gli3 3 0.36 2.65 1.46
89 INT207521 Gene_expression of Tfap2a 7 0.48 1.89 1.45
90 INT255251 Negative_regulation of Smad2 12 0.32 5.69 1.44
91 INT270631 Gene_expression of Insig1 15 0.32 5.19 1.43
92 INT32184 Negative_regulation of Col2a1 9 0.42 3.05 1.43
93 INT340596 Negative_regulation of Gene_expression of Wnt3a 1 0.51 0.38 1.4
94 INT224501 Positive_regulation of Gene_expression of EPHB2 9 0.49 4.29 1.39
95 INT222228 Positive_regulation of Gene_expression of Tcf21 4 0.38 0.84 1.39
96 INT110485 Binding of Tcf21 2 0.36 0.76 1.37
97 INT203491 Gene_expression of Msc 40 0.64 36.05 1.35
98 INT129619 Phosphorylation of Smad2 34 0.61 11.6 1.34
99 INT152951 Negative_regulation of LEF1 5 0.41 3.22 1.31
100 INT54831 Regulation of Gene_expression of Col2a1 4 0.39 2.3 1.31
101 INT117232 Localization of COL2A1 11 0.72 7.34 1.3
102 INT109924 Localization of EPHB2 6 0.73 2.07 1.28
103 INT38067 Transcription of MSC 1 0.55 0.55 1.25
104 INT128714 Transcription of Col2a1 6 0.52 2.13 1.24
105 INT316154 Positive_regulation of TCF21 4 0.17 1.22 1.23
106 INT20764 Localization of INHBA 3 0.71 0.94 1.22
107 INT175452 Negative_regulation of Positive_regulation of Hand2 4 0.21 3.78 1.21
108 INT138726 Positive_regulation of Gene_expression of Msx1 5 0.53 1.73 1.2
109 INT176463 Protein_catabolism of Col2a1 4 0.35 1.94 1.2
110 INT108519 Binding of Lrp6 8 0.44 1.47 1.19
111 INT83805 Binding of EPHB3 1 0.00 1.15 1.19
112 INT310164 Negative_regulation of Gene_expression of Tgfbr1 9 0.40 6.11 1.17
113 INT150074 Gene_expression of WNT5A 8 0.75 6.3 1.17
114 INT108334 Negative_regulation of Phosphorylation of EPHB2 4 0.57 2.27 1.16
115 INT20762 Negative_regulation of Localization of INHBA 1 0.03 0 1.15
116 INT253191 Positive_regulation of Gene_expression of Shh 2 0.66 2.57 1.14
117 INT11658 Regulation of Gene_expression of COL2A1 9 0.62 3.09 1.11
118 INT54835 Regulation of Col2a1 5 0.59 2.08 1.07
119 INT332771 Phosphorylation of Tcf21 1 0.09 0.21 1.07
120 INT332772 Positive_regulation of Phosphorylation of Tcf21 1 0.06 0.21 1.07
121 INT165530 Positive_regulation of Shh 4 0.69 1.21 1.05
122 INT84511 Positive_regulation of Tfap2a 3 0.27 0.72 1.04
123 INT97032 Gene_expression of Snai1 3 0.52 0.58 1.04
124 INT238596 Gene_expression of Sumo1 1 0.44 0.25 1.02
125 INT127647 Regulation of Wnt7a 3 0.07 1.28 1.01
126 INT37914 Regulation of Negative_regulation of Chd7 1 0.12 0 1
127 INT168233 Positive_regulation of Transcription of Col2a1 2 0.45 1.78 0.99
128 INT235516 Positive_regulation of Localization of Hand2 4 0.36 3.04 0.97
129 INT226419 Negative_regulation of Localization of Hand2 4 0.30 3.17 0.96
130 INT20763 Positive_regulation of Localization of INHBA 1 0.03 0 0.96
131 INT340604 Regulation of Wnt3a 1 0.24 0 0.95
132 INT243974 Binding of Tfap2a 7 0.18 1.36 0.93
133 INT218696 Negative_regulation of Phosphorylation of Smad2 3 0.42 4.36 0.92
134 INT171851 Gene_expression of Sumo1 13 0.30 10.7 0.89
135 INT102677 Negative_regulation of TCF21 2 0.41 0.22 0.89
136 INT127109 Negative_regulation of Regulation of Inhba 1 0.38 0.5 0.88
137 INT173626 Negative_regulation of MSC 9 0.47 3.28 0.87
138 INT265313 Positive_regulation of Tgfbr1 8 0.66 2.95 0.87
139 INT277586 Negative_regulation of Mef2c 36 0.59 11.03 0.86
140 INT181812 Positive_regulation of Msc 20 0.66 13.47 0.86
141 INT112014 Negative_regulation of Regulation of Hand2 3 0.34 2.07 0.86
142 INT107939 Regulation of TGFBR2 1 0.37 0.98 0.84
143 INT221796 Positive_regulation of Gene_expression of Tfap2a 2 0.10 1.19 0.83
144 INT278710 Phosphorylation of LEF1 1 0.05 0.76 0.82
145 INT119102 Gene_expression of PDGFRA 13 0.75 11.99 0.81
146 INT267095 Regulation of Gene_expression of Smad2 3 0.44 1.77 0.8
147 INT14871 Binding of TGFB3 3 0.13 1.2 0.78
148 INT20765 Negative_regulation of INHBA 6 0.34 1.91 0.77
149 INT109912 Positive_regulation of Localization of EPHB2 2 0.49 0.56 0.77
150 INT196325 Positive_regulation of Gene_expression of Chd7 7 0.14 4.28 0.76
151 INT173506 Positive_regulation of Col2a1 4 0.20 3.42 0.76
152 INT161947 Positive_regulation of TGFBR1 2 0.52 1.6 0.76
153 INT137007 Gene_expression of SMAD2 6 0.75 2.53 0.75
154 INT207535 Transcription of Tfap2a 3 0.31 0.98 0.74
155 INT95617 Regulation of Msx1 2 0.56 1.05 0.73
156 INT47481 Localization of SUMO1 1 0.01 0 0.73
157 INT265318 Negative_regulation of Gene_expression of Smad2 8 0.26 2.16 0.72
158 INT172960 Negative_regulation of Gene_expression of Smad4 7 0.39 5.88 0.71
159 INT37617 Regulation of Gene_expression of Col2a1 3 0.31 1.48 0.7
160 INT269896 Positive_regulation of Gene_expression of Smad2 9 0.40 2.15 0.69
161 INT135197 Gene_expression of Tfap2a 1 0.45 0.48 0.69
162 INT68560 Regulation of Gli3 3 0.18 1.51 0.68
163 INT202361 Gene_expression of Mef2c 28 0.78 5.53 0.67
164 INT271488 Negative_regulation of Negative_regulation of Hand2 3 0.18 2.36 0.67
165 INT137009 Negative_regulation of Gene_expression of SMAD2 4 0.42 1.76 0.66
166 INT268377 Phosphorylation of SMAD2 7 0.80 0.85 0.65
167 INT75043 Binding of Msx1 6 0.35 2.36 0.65
168 INT28958 Negative_regulation of Wnt7a 3 0.45 0.49 0.65
169 INT302664 Positive_regulation of SMAD2 2 0.49 0.85 0.64
170 INT197832 Localization of MEN1 1 0.80 11.01 0.63
171 INT63389 Localization of Col2a1 7 0.68 1.95 0.6
172 INT207529 Localization of Tfap2a 2 0.34 0.13 0.6
173 INT80300 Gene_expression of TFAP2A 5 0.54 2.76 0.59
174 INT150075 Positive_regulation of Gene_expression of WNT5A 2 0.67 2.53 0.59
175 INT281366 Regulation of Tcf21 1 0.09 0.23 0.59
176 INT54000 Positive_regulation of SNAI1 7 0.49 5.37 0.58
177 INT132588 Positive_regulation of Negative_regulation of Hand2 1 0.03 0.47 0.58
178 INT32921 Positive_regulation of Msx1 4 0.47 0.99 0.57
179 INT144922 Gene_expression of TGFBR1 4 0.72 0.19 0.57
180 INT127648 Gene_expression of Wnt7a 2 0.13 1.11 0.56
181 INT243970 Phosphorylation of Tfap2a 2 0.25 0.56 0.56
182 INT316161 Negative_regulation of Gene_expression of TCF21 1 0.10 0.11 0.56
183 INT3831 Negative_regulation of TGFBR2 4 0.28 4.99 0.55
184 INT103781 Negative_regulation of Smad4 9 0.42 4.42 0.54
185 INT278982 Regulation of EPHB2 6 0.44 1.97 0.53
186 INT127114 Regulation of Phosphorylation of Inhba 1 0.41 0.52 0.53
187 INT127107 Phosphorylation of Inhba 1 0.73 0.52 0.53
188 INT125139 Regulation of Gene_expression of EPHB2 3 0.44 1.07 0.52
189 INT135062 Transcription of Gli3 1 0.05 0 0.52
190 INT224498 Regulation of Positive_regulation of EPHB2 1 0.26 0.46 0.52
191 INT158889 Gene_expression of Smad2 5 0.65 1.25 0.51
192 INT120403 Regulation of Phosphorylation of EPHB2 2 0.60 1.92 0.5
193 INT62104 Localization of INSIG2 1 0.01 0 0.5
194 INT100698 Regulation of Chd7 6 0.34 1.85 0.49
195 INT32183 Positive_regulation of Negative_regulation of Col2a1 2 0.46 1.01 0.49
196 INT20766 Positive_regulation of INHBA 4 0.66 5.66 0.48
197 INT206484 Localization of Shh 2 0.75 1.14 0.46
198 INT340598 Binding of Wnt3a 1 0.33 0.15 0.46
199 INT125840 Positive_regulation of Binding of Col2a1 1 0.43 1.21 0.45
200 INT222229 Localization of Tcf21 1 0.57 0.45 0.45
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox