GO:0060037

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Name pharyngeal system development
Categary Process
Go Slim No
Go Link GO:0060037
Unique Molecular Interactions 140
Total Molecular Interactions 195
Total Single Events 790
Pain Genes Associated 22

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for pharyngeal system development. They are ordered first by their pain relevance and then by number of times they were reported for pharyngeal system development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT250867 Fgf8 Positive_regulation of Protein_catabolism of Ecm1 1 0.06 4.35 2.14
2 INT95275 Binding of Edn1 and Ece1 1 0.32 2.09 1.3
3 INT95274 Regulation of Binding of Edn1 and Ece1 1 0.39 2.09 1.3
4 INT89878 Pdyn Positive_regulation of Gene_expression of Nkx2-5 1 0.35 0 1.29
5 INT168185 Binding of PLXNA2 and MRI1 1 0.25 0.78 1.08
6 INT133072 GATA3 Positive_regulation of Transcription of OPRM1 1 0.35 0 1.04
7 INT75486 Binding of Tgfbr1 and Tgfbr2 1 0.10 1.94 1.02
8 INT133071 STAT6 Positive_regulation of Gene_expression of GATA3 1 0.55 0 0.95
9 INT250868 Fgf8 Positive_regulation of Gene_expression of Mmp3 1 0.15 1.73 0.93
10 INT250861 Fgf8 Positive_regulation of Gene_expression of Ptger2 1 0.04 1.51 0.84
11 INT161951 Positive_regulation of TGFBR1 Positive_regulation of Gene_expression of Ngf 1 0.27 0.99 0.76
12 INT161945 TGFB2 Positive_regulation of TGFBR1 1 0.08 0.99 0.76
13 INT161950 TGFBR1 Negative_regulation of Localization of Ngf 1 0.23 1.01 0.72
14 INT89877 Pdyn Positive_regulation of Nkx2-5 1 0.11 0 0.64
15 INT139079 Tnip1 Negative_regulation of Ptch1 1 0.20 0.63 0.62
16 INT250852 Fgf8 Negative_regulation of Gene_expression of Ecm1 1 0.04 1.1 0.54
17 INT302644 ARSA Positive_regulation of Gene_expression of TGFBR1 1 0.04 0.29 0.51
18 INT302647 ARSA Positive_regulation of TGFBR1 1 0.03 0.29 0.51
19 INT173475 Bcar1 Regulation of Isl1 1 0.01 0 0.47
20 INT335850 Snrpc Negative_regulation of Gene_expression of Isl1 1 0.00 1.51 0.45
21 INT75488 Binding of TGFB1 and Tgfbr1 1 0.23 0.78 0.41
22 INT250870 Fgf8 Positive_regulation of Ecm1 1 0.04 0.79 0.38
23 INT161796 Binding of ECE1 and EDN1 2 0.21 2.23 0.34
24 INT67266 Edn1 Negative_regulation of Ece1 1 0.19 0.17 0.32
25 INT300752 GATA3 Regulation of Hand2 1 0.01 0.06 0.3
26 INT250856 Fgf8 Positive_regulation of Localization of Mmp3 1 0.11 0.51 0.3
27 INT109067 Pdyn Positive_regulation of Gene_expression of NKX2-5 1 0.01 0 0.29
28 INT191501 NLRP3 Positive_regulation of ECE1 1 0.01 1.09 0.28
29 INT250864 Fgf8 Positive_regulation of Positive_regulation of Ptger2 1 0.03 0.55 0.28
30 INT250854 Fgf8 Positive_regulation of Positive_regulation of Mmp3 1 0.11 0.55 0.28
31 INT191495 NLRP3 Positive_regulation of Protein_catabolism of ECE1 1 0.01 1.09 0.28
32 INT311918 Insrr Negative_regulation of Tgfbr1 1 0.00 0.87 0.26
33 INT311902 Acvrl1 Negative_regulation of Tgfbr1 1 0.13 0.87 0.26
34 INT317773 Positive_regulation of GATA3 Positive_regulation of HDAC1 1 0.23 0.69 0.25
35 INT317775 GATA3 Positive_regulation of HDAC1 1 0.23 0.69 0.25
36 INT250873 Fgf8 Positive_regulation of GAG 1 0.55 0.48 0.23
37 INT311911 Tgfbr1 Positive_regulation of Gene_expression of Mmp13 1 0.10 0.55 0.23
38 INT297545 Pou3f3 Regulation of Hes1 1 0.05 0.41 0.2
39 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19
40 INT339336 Binding of NKX3-1 and TAC4 1 0.03 0.08 0.18
41 INT306425 Positive_regulation of Binding of TBX1 and VCF 1 0.02 1.15 0.18
42 INT306426 Binding of TBX1 and VCF 1 0.01 1.09 0.17
43 INT194829 Gata3 Positive_regulation of IL13 1 0.01 0.12 0.15
44 INT194835 Gata3 Positive_regulation of IL5 1 0.01 0.12 0.15
45 INT194833 Binding of IL5 and Gata3 1 0.01 0.12 0.15
46 INT194827 Binding of IL13 and Gata3 1 0.01 0.12 0.15
47 INT161797 Binding of ECE1 and ING1 1 0.01 0.68 0.14
48 INT324898 Ece1 Regulation of Gene_expression of Edn1 1 0.17 0.8 0.14
49 INT161795 Positive_regulation of Binding of ECE1 and ING1 1 0.02 0.68 0.14
50 INT161799 Positive_regulation of Binding of ECE1 and EDN1 1 0.07 0.68 0.14
51 INT250863 Fgf8 Positive_regulation of Ptger2 1 0.03 0.19 0.14
52 INT338428 Il4 Positive_regulation of Gata3 1 0.06 0.75 0.13
53 INT345343 PTCH1 Regulation of Negative_regulation of SMO 1 0.09 2.3 0.13
54 INT250866 Binding of Fgfr4 and Fgf8 1 0.12 0.35 0.11
55 INT208938 Positive_regulation of Tacr1 Positive_regulation of Nkx2-5 1 0.17 0 0.1
56 INT297548 Neurod1 Regulation of Hes1 1 0.05 0.2 0.1
57 INT250860 Fgf8 Regulation of Localization of Ptger2 1 0.02 0.13 0.1
58 INT262751 Binding of PTCH1 and SMO 1 0.25 1.29 0.1
59 INT250862 Fgf8 Regulation of Localization of Mmp3 1 0.13 0.13 0.1
60 INT250859 Fgf8 Negative_regulation of Gene_expression of Mmp3 1 0.09 0.12 0.09
61 INT250872 Fgf8 Positive_regulation of Mmp3 1 0.11 0.12 0.09
62 INT270457 Binding of Ptch1 and Gli1 1 0.02 1.3 0.08
63 INT311917 Gene_expression of Tgfbr1 Positive_regulation of Gene_expression of Mmp13 1 0.10 0.31 0.08
64 INT208943 Nfkb1 Positive_regulation of Nkx2-5 1 0.11 0.38 0.08
65 INT324896 Ece1 Positive_regulation of Negative_regulation of Edn1 1 0.19 0.42 0.07
66 INT311915 Tgfbr1 Negative_regulation of Gene_expression of Mmp13 1 0.09 0.27 0.06
67 INT250865 Binding of Fgf8 and Fgfr3 1 0.18 0.3 0.05
68 INT250855 Binding of Fgfr2 and Fgf8 1 0.12 0.3 0.05
69 INT208945 Nkx2-5 Positive_regulation of Gene_expression of Nppa 1 0.03 0.33 0.05
70 INT235640 Binding of GATA3 and Mrgpre 1 0.01 0.8 0.04
71 INT305383 Binding of NKX2-5 and FLNA 1 0.10 0.7 0.04
72 INT255756 Ptch1 Positive_regulation of Phosphorylation of Pik3r1 1 0.16 1.08 0.03
73 INT265347 Binding of Ocln and Tgfbr1 1 0.18 0.06 0.03
74 INT265345 Binding of Tgfbr1 and Tjp1 1 0.09 0.06 0.03
75 INT255733 Ptch1 Positive_regulation of Pik3r1 1 0.16 1.08 0.03
76 INT311655 Shh Positive_regulation of Gene_expression of Fgf8 1 0.31 0.18 0.03
77 INT265343 Positive_regulation of Binding of Tgfbr1 and Tjp1 1 0.12 0.06 0.03
78 INT265348 Positive_regulation of Binding of Ocln and Tgfbr1 1 0.25 0.06 0.03
79 INT244856 Lbx1 Regulation of Isl1 1 0.60 0 0
80 INT255758 Ptch1 Positive_regulation of Akt1 1 0.21 1.14 0
81 INT265231 Binding of FKBP1A and TGFBR1 1 0.11 0.35 0
82 INT255732 Ptch1 Positive_regulation of hs 1 0.06 1.26 0
83 INT264735 Binding of Hes1 and Mir199b 1 0.08 0.93 0
84 INT205975 Binding of PTCH1 and Smo 1 0.02 0.72 0
85 INT264738 Mir199b Regulation of Gene_expression of Hes1 1 0.08 0.89 0
86 INT337915 Tgfbr1 Positive_regulation of Negative_regulation of Smad2 1 0.05 0.15 0
87 INT265344 sb Negative_regulation of Tgfbr1 1 0.00 0.06 0
88 INT255755 Ptch1 Regulation of Positive_regulation of Ins1 1 0.05 0.28 0
89 INT264736 Hes1 Regulation of Notch2 1 0.20 0.13 0
90 INT172838 Binding of ISL1 and T2dm2 1 0.00 2.41 0
91 INT205958 GLI1 Positive_regulation of Gene_expression of PTCH1 1 0.35 0.57 0
92 INT205960 Binding of PTCH1 and SHH 1 0.21 0.71 0
93 INT270461 Shh Regulation of Gene_expression of Ptch1 1 0.48 0.07 0
94 INT197316 Hes1 Regulation of Atoh1 1 0.01 0.14 0
95 INT255753 Ptch1 Positive_regulation of Phosphorylation of Gopc 1 0.13 1.33 0
96 INT323254 Binding of Ptprv and Isl1 1 0.00 0.6 0
97 INT244860 Lbx1 Negative_regulation of Isl1 1 0.16 0 0
98 INT314866 Binding of Six1 and Sall1 1 0.39 0.76 0
99 INT197304 Ahr Regulation of Hes1 1 0.06 0.17 0
100 INT264731 Gene_expression of Hes1 Negative_regulation of Positive_regulation of Musd1 1 0.00 0.18 0
101 INT260074 Binding of BRCA2 and PTCH1 1 0.40 0.15 0
102 INT323253 Binding of Ins1 and Isl1 1 0.00 0.59 0
103 INT256632 Binding of PTCH1 and Jkamp 1 0.00 2.32 0
104 INT272520 Gene_expression of Dmpk Positive_regulation of Positive_regulation of Nkx2-5 1 0.02 0.43 0
105 INT255744 Binding of hs and Ptch1 1 0.06 1.32 0
106 INT205965 Binding of Ptch1 and Smo 1 0.03 0.72 0
107 INT323251 Binding of Isl1 and Uchl1 1 0.00 0.6 0
108 INT270466 Ptch1 Regulation of Gene_expression of Shh 1 0.48 0.07 0
109 INT255750 Ptch1 Positive_regulation of Ins1 1 0.10 0.35 0
110 INT260073 Binding of FANCC and PTCH1 1 0.33 0.49 0
111 INT264729 Mir199b Regulation of Hes1 1 0.05 0.25 0
112 INT260067 Binding of PTCH1 and XPA 1 0.26 1.08 0
113 INT205976 Binding of Ptch1 and SMOX 1 0.21 0.72 0
114 INT205962 Binding of PTCH1 and SMOX 1 0.14 0.72 0
115 INT310192 Tgfbr1 Positive_regulation of Regulation of Acvrl1 1 0.01 0 0
116 INT213556 Binding of Eya1 and Six1 1 0.41 0.48 0
117 INT272521 Binding of DMPK and Nkx2-5 1 0.01 0.42 0
118 INT255734 Ptch1 Regulation of Ins1 1 0.09 1.46 0
119 INT197310 Hes1 Regulation of Ascl1 1 0.01 0.14 0
120 INT264725 Binding of Hes1 and Notch1 1 0.03 0.84 0
121 INT255760 Ptch1 Regulation of TNF 1 0.13 1.33 0
122 INT255741 Ptch1 Positive_regulation of Phosphorylation of Ins1 1 0.09 2.21 0
123 INT264734 Mir199b Negative_regulation of Negative_regulation of Hes1 1 0.07 0.1 0
124 INT205977 Binding of SHH and Ptch1 1 0.31 0.71 0
125 INT205961 GLI1 Positive_regulation of Negative_regulation of PTCH1 1 0.25 0.58 0
126 INT243232 Ighmbp2 Negative_regulation of Ptch1 1 0.02 0.22 0
127 INT255749 Ptch1 Positive_regulation of Phosphorylation of Slc2a4 1 0.15 1.32 0
128 INT255735 Ptch1 Positive_regulation of Phosphorylation of Akt1 1 0.27 2.83 0
129 INT337917 Binding of sb and Tgfbr1 1 0.00 1.06 0
130 INT255746 Hspa1a Positive_regulation of Positive_regulation of Ptch1 1 0.19 0.99 0
131 INT255739 Ptch1 Positive_regulation of Gene_expression of Hspa1a 1 0.18 0.75 0
132 INT264739 Mir199b Negative_regulation of Gene_expression of Hes1 1 0.07 0.82 0
133 INT264737 Hes1 Regulation of Shh 1 0.19 0.13 0
134 INT255759 Ptch1 Positive_regulation of Phosphorylation of hs 1 0.06 1.34 0
135 INT264733 Hes1 Regulation of Mir199b 1 0.05 0.43 0
136 INT323252 Binding of H2-Ab1 and Isl1 1 0.00 0.6 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for pharyngeal system development. They are ordered first by their pain relevance and then by number of times they were reported in pharyngeal system development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT250832 Gene_expression of Fgf8 1 0.77 13.36 6.2
2 INT203443 Gene_expression of Isl1 27 0.67 11.12 4.65
3 INT116011 Positive_regulation of Gata3 5 0.31 3.17 4.21
4 INT202417 Gene_expression of Gata3 16 0.61 7.84 4.12
5 INT75484 Gene_expression of Tgfbr1 21 0.64 13.36 3.15
6 INT133080 Gene_expression of GATA3 15 0.61 5.64 2.89
7 INT168188 Gene_expression of PLXNA2 13 0.58 9 2.73
8 INT202419 Positive_regulation of Gene_expression of Gata3 6 0.52 5.47 2.6
9 INT37294 Negative_regulation of Ece1 6 0.54 1.27 1.74
10 INT250841 Positive_regulation of Gene_expression of Fgf8 1 0.69 3.8 1.72
11 INT89865 Gene_expression of Nkx2-5 14 0.75 2.99 1.58
12 INT116014 Transcription of Gata3 4 0.63 2.24 1.46
13 INT116015 Regulation of Gata3 3 0.22 1.41 1.42
14 INT113151 Positive_regulation of Ptch1 7 0.64 3.8 1.41
15 INT116008 Binding of Gata3 2 0.34 1.37 1.41
16 INT92955 Gene_expression of Ece1 5 0.74 2.2 1.36
17 INT250850 Negative_regulation of Gene_expression of Fgf8 1 0.42 2.79 1.33
18 INT92954 Positive_regulation of Gene_expression of Ece1 2 0.48 2.16 1.32
19 INT95270 Regulation of Ece1 1 0.43 2.08 1.3
20 INT139077 Negative_regulation of Ptch1 5 0.56 5.22 1.29
21 INT116016 Positive_regulation of Positive_regulation of Gata3 2 0.21 0.5 1.28
22 INT200838 Positive_regulation of Isl1 6 0.60 0.73 1.19
23 INT310164 Negative_regulation of Gene_expression of Tgfbr1 9 0.40 6.11 1.17
24 INT172809 Gene_expression of ISL1 33 0.40 21.63 1.12
25 INT87233 Gene_expression of ECE1 12 0.65 3.54 1.12
26 INT133079 Positive_regulation of Gene_expression of GATA3 3 0.50 1.03 1.11
27 INT250840 Negative_regulation of Fgf8 1 0.43 1.92 1.11
28 INT277461 Positive_regulation of Gene_expression of Fgf8 1 0.24 0.47 1.05
29 INT161716 Localization of Nkx2-5 2 0.74 2.17 1.02
30 INT109075 Positive_regulation of Transcription of NKX2-5 1 0.67 0 1.02
31 INT109074 Transcription of NKX2-5 1 0.69 0 1.01
32 INT265313 Positive_regulation of Tgfbr1 8 0.66 2.95 0.87
33 INT297531 Negative_regulation of Ece1 5 0.32 5.49 0.87
34 INT135299 Binding of PTCH1 10 0.48 12.16 0.84
35 INT173472 Positive_regulation of Isl1 1 0.03 0.2 0.83
36 INT109062 Gene_expression of NKX2-5 7 0.75 3.31 0.82
37 INT258932 Positive_regulation of TBX1 3 0.39 2.73 0.82
38 INT161947 Positive_regulation of TGFBR1 2 0.52 1.6 0.76
39 INT84726 Gene_expression of NKX3-1 4 0.75 2.1 0.75
40 INT168189 Positive_regulation of PLXNA2 1 0.20 0.49 0.75
41 INT142416 Binding of Ptch1 6 0.34 4.92 0.74
42 INT116012 Regulation of Positive_regulation of Gata3 1 0.20 0.07 0.71
43 INT116006 Positive_regulation of Transcription of Gata3 1 0.21 0.07 0.7
44 INT116010 Positive_regulation of Binding of Gata3 1 0.31 0.07 0.7
45 INT243779 Negative_regulation of Gene_expression of Isl1 2 0.30 2.62 0.68
46 INT153257 Regulation of Ptch1 6 0.36 5.92 0.67
47 INT268451 Positive_regulation of Gene_expression of ECE1 3 0.49 1.99 0.67
48 INT342318 Localization of PLXNA2 1 0.25 0.75 0.67
49 INT202416 Negative_regulation of Gata3 2 0.32 1.17 0.64
50 INT264709 Gene_expression of Hes1 24 0.76 7.04 0.63
51 INT89861 Negative_regulation of Nkx2-5 3 0.19 0.12 0.63
52 INT17840 Negative_regulation of GATA3 3 0.41 1.96 0.63
53 INT205470 Positive_regulation of GATA3 4 0.33 2.53 0.61
54 INT226838 Transcription of Isl1 2 0.28 0.36 0.6
55 INT290660 Negative_regulation of Gene_expression of Gata3 1 0.25 1.52 0.6
56 INT144922 Gene_expression of TGFBR1 4 0.72 0.19 0.57
57 INT226481 Negative_regulation of Gene_expression of GATA3 1 0.06 1.41 0.57
58 INT65919 Gene_expression of Ptch1 11 0.75 6.47 0.56
59 INT89869 Negative_regulation of Gene_expression of Nkx2-5 1 0.41 0 0.56
60 INT88705 Localization of Ece1 2 0.22 2.07 0.55
61 INT144053 Transcription of GATA3 1 0.67 0.89 0.54
62 INT87230 Localization of ECE1 5 0.80 1.51 0.53
63 INT156254 Gene_expression of Six1 7 0.67 1.52 0.51
64 INT181281 Localization of NKX3-1 1 0.12 0.3 0.5
65 INT305390 Negative_regulation of NKX2-5 2 0.37 2.24 0.49
66 INT250845 Protein_catabolism of Fgf8 1 0.98 1.64 0.48
67 INT329319 Positive_regulation of Transcription of Ece1 1 0.08 2.64 0.48
68 INT268007 Gene_expression of Fgf8 8 0.72 1.38 0.47
69 INT299799 Negative_regulation of Negative_regulation of GATA3 1 0.09 1.32 0.47
70 INT248346 Binding of PLXNA2 4 0.29 1.38 0.46
71 INT84724 Negative_regulation of Gene_expression of NKX3-1 1 0.41 0.43 0.44
72 INT159221 Negative_regulation of TBX1 4 0.41 4.22 0.43
73 INT277465 Regulation of Gene_expression of Fgf8 2 0.25 0.43 0.43
74 INT93926 Gene_expression of Ece1 3 0.27 2.31 0.42
75 INT65606 Binding of TBX1 2 0.30 3.13 0.41
76 INT324886 Transcription of Ece1 2 0.37 1.95 0.4
77 INT292484 Negative_regulation of TGFBR1 3 0.19 0.75 0.39
78 INT17937 Gene_expression of Isl1 4 0.27 0.48 0.36
79 INT254816 Negative_regulation of Tgfbr1 20 0.55 9.24 0.34
80 INT250826 Transcription of Fgf8 1 0.71 0.71 0.34
81 INT61124 Localization of Ece1 1 0.58 0.08 0.32
82 INT172806 Localization of ISL1 4 0.26 2.64 0.29
83 INT311881 Regulation of Positive_regulation of Tgfbr1 1 0.22 0.97 0.29
84 INT269082 Gene_expression of TBX1 1 0.14 0.36 0.28
85 INT191535 Protein_catabolism of ECE1 1 0.07 1.03 0.28
86 INT78132 Binding of Isl1 1 0.16 0 0.27
87 INT183055 Gene_expression of PTCH1 10 0.77 15.54 0.26
88 INT25465 Positive_regulation of ISL1 6 0.15 3.59 0.26
89 INT173797 Negative_regulation of Isl1 3 0.37 0.15 0.26
90 INT173792 Negative_regulation of Negative_regulation of Isl1 1 0.08 0.15 0.26
91 INT208915 Positive_regulation of Nkx2-5 3 0.29 1.02 0.25
92 INT274104 Regulation of PLXNA2 2 0.33 2.66 0.25
93 INT250836 Binding of Fgf8 3 0.35 0.66 0.24
94 INT329320 Positive_regulation of Gene_expression of Ece1 1 0.09 1.31 0.24
95 INT306427 Localization of TBX1 1 0.20 1.08 0.23
96 INT306428 Positive_regulation of Localization of TBX1 1 0.14 1.08 0.23
97 INT324884 Positive_regulation of Ece1 2 0.37 0.86 0.22
98 INT248347 Negative_regulation of PLXNA2 1 0.38 0.24 0.22
99 INT305392 Binding of NKX2-5 1 0.22 0.93 0.21
100 INT250833 Localization of Fgf8 1 0.74 0.46 0.21
101 INT250842 Negative_regulation of Binding of Fgf8 1 0.43 0.33 0.21
102 INT205087 Positive_regulation of Gene_expression of ISL1 4 0.26 3.86 0.19
103 INT324882 Regulation of Transcription of Ece1 1 0.24 0.66 0.19
104 INT311886 Phosphorylation of Tgfbr1 1 0.40 0.7 0.19
105 INT243778 Binding of Isl1 1 0.26 0 0.19
106 INT264701 Negative_regulation of Gene_expression of Hes1 1 0.42 0.73 0.18
107 INT339342 Binding of NKX3-1 1 0.04 0.08 0.18
108 INT311446 Negative_regulation of Gene_expression of PLXNA2 1 0.12 1.1 0.18
109 INT87231 Binding of ECE1 4 0.37 0.47 0.16
110 INT98772 Localization of Isl1 2 0.65 0 0.16
111 INT201210 Negative_regulation of ISL1 2 0.02 0.4 0.16
112 INT208925 Positive_regulation of Localization of Nkx2-5 1 0.21 0.14 0.16
113 INT250835 Positive_regulation of Fgf8 1 0.50 0.42 0.14
114 INT146415 Regulation of Nkx2-5 3 0.44 0.91 0.13
115 INT302662 Negative_regulation of Negative_regulation of TGFBR1 1 0.14 0 0.13
116 INT161805 Positive_regulation of ECE1 1 0.12 0.61 0.13
117 INT98774 Regulation of Localization of Isl1 1 0.08 0 0.13
118 INT194746 Phosphorylation of Gata3 1 0.10 0.08 0.12
119 INT162568 Regulation of TBX1 3 0.35 1.54 0.11
120 INT258933 Protein_catabolism of TBX1 1 0.43 0.75 0.11
121 INT208922 Transcription of Nkx2-5 2 0.29 0.36 0.1
122 INT323415 Regulation of NKX2-5 1 0.39 0.71 0.1
123 INT208917 Positive_regulation of Transcription of Nkx2-5 1 0.21 0 0.1
124 INT87232 Regulation of ECE1 1 0.45 0.16 0.1
125 INT323416 Localization of NKX2-5 1 0.65 1.75 0.1
126 INT207829 Positive_regulation of Localization of ISL1 1 0.02 0.1 0.1
127 INT260083 Regulation of PTCH1 11 0.27 4.46 0.09
128 INT208918 Positive_regulation of Gene_expression of Nkx2-5 3 0.23 0.48 0.09
129 INT173473 Positive_regulation of Positive_regulation of Isl1 1 0.02 0.06 0.09
130 INT270454 Regulation of Transcription of Ptch1 1 0.25 0.55 0.09
131 INT254819 Regulation of Negative_regulation of Tgfbr1 1 0.15 1.2 0.09
132 INT173470 Positive_regulation of Phosphorylation of Isl1 1 0.02 0 0.09
133 INT173471 Phosphorylation of Isl1 1 0.04 0 0.09
134 INT270450 Transcription of Ptch1 1 0.49 0.55 0.09
135 INT49260 Negative_regulation of ECE1 7 0.57 0.24 0.08
136 INT165148 Regulation of Binding of Ptch1 1 0.22 0.08 0.08
137 INT270452 Regulation of Gene_expression of Ptch1 1 0.25 0.25 0.08
138 INT305387 Positive_regulation of Gene_expression of NKX2-5 1 0.31 0.72 0.07
139 INT354592 Positive_regulation of Gene_expression of PLXNA2 1 0.04 0.37 0.07
140 INT165154 Negative_regulation of Positive_regulation of Ptch1 1 0.34 0.09 0.07
141 INT183056 Positive_regulation of Transcription of PTCH1 1 0.28 0.46 0.07
142 INT311885 Positive_regulation of Gene_expression of Tgfbr1 2 0.44 0.35 0.06
143 INT255719 Phosphorylation of Ptch1 1 0.32 3.7 0.06
144 INT298237 Regulation of Isl1 1 0.03 0.24 0.06
145 INT208924 Gene_expression of Eya1 1 0.34 0.33 0.05
146 INT126436 Regulation of Gene_expression of Ece1 1 0.21 0.05 0.05
147 INT255726 Localization of Ptch1 1 0.33 1.74 0.05
148 INT354593 Regulation of Gene_expression of PLXNA2 1 0.04 0.34 0.05
149 INT197017 Binding of GATA3 2 0.36 0.94 0.04
150 INT183070 Transcription of PTCH1 2 0.68 0.95 0.04
151 INT264717 Negative_regulation of Hes1 7 0.42 0.77 0.03
152 INT264704 Regulation of Hes1 4 0.44 1.03 0.03
153 INT183064 Regulation of Gene_expression of PTCH1 1 0.34 0.22 0.03
154 INT352541 Transcription of ISL1 1 0.36 0.2 0.03
155 INT264702 Positive_regulation of Gene_expression of Hes1 1 0.68 1.39 0.03
156 INT205968 Negative_regulation of PTCH1 2 0.58 2.35 0
157 INT255723 Positive_regulation of Gene_expression of Ptch1 2 0.39 1.3 0
158 INT264719 Regulation of Gene_expression of Hes1 2 0.28 0.12 0
159 INT255789 Protein_catabolism of Ece1 2 0.35 1.06 0
160 INT265316 Binding of Tgfbr1 2 0.35 0.59 0
161 INT265326 Regulation of Tgfbr1 2 0.43 0.17 0
162 INT256631 Positive_regulation of PTCH1 2 0.13 1.97 0
163 INT180121 Phosphorylation of Isl1 1 0.27 0 0
164 INT264708 Transcription of Hes1 1 0.67 0.83 0
165 INT180097 Positive_regulation of Phosphorylation of Isl1 1 0.17 0 0
166 INT260088 Negative_regulation of Transcription of PTCH1 1 0.43 0.4 0
167 INT315214 Negative_regulation of Regulation of Tgfbr1 1 0.41 0 0
168 INT268388 Positive_regulation of Positive_regulation of TGFBR1 1 0.35 0.61 0
169 INT227625 Regulation of ISL1 1 0.05 0.35 0
170 INT213510 Localization of Eya1 1 0.65 0 0
171 INT260089 Localization of PTCH1 1 0.70 0.37 0
172 INT264705 Binding of Hes1 1 0.35 0.07 0
173 INT272228 Localization of TGFBR1 1 0.34 0.74 0
174 INT235637 Localization of GATA3 1 0.73 0.55 0
175 INT314739 Transcription of TBX1 1 0.32 0.8 0
176 INT264706 Positive_regulation of Hes1 1 0.40 0.14 0
177 INT270455 Negative_regulation of Gene_expression of Ptch1 1 0.39 0.66 0
178 INT265319 Positive_regulation of Negative_regulation of Tgfbr1 1 0.47 0.53 0
179 INT144920 Positive_regulation of Gene_expression of TGFBR1 1 0.65 0 0
180 INT243780 Positive_regulation of Gene_expression of Isl1 1 0.35 0 0
181 INT250830 Regulation of Protein_catabolism of Fgf8 1 0.45 0.08 0
182 INT311651 Positive_regulation of Fgf8 1 0.46 0.26 0
183 INT183071 Negative_regulation of Gene_expression of ISL1 1 0.20 0.34 0
184 INT213525 Regulation of Localization of Eya1 1 0.39 0 0
185 INT226248 Negative_regulation of Negative_regulation of ECE1 1 0.05 0 0
186 INT250846 Positive_regulation of Protein_catabolism of Fgf8 1 0.50 0.07 0
187 INT310176 Localization of Tgfbr1 1 0.11 0.83 0
188 INT233573 Negative_regulation of NKX3-1 1 0.42 1.49 0
189 INT310179 Positive_regulation of Positive_regulation of Tgfbr1 1 0.08 0 0
190 INT183052 Positive_regulation of Gene_expression of PTCH1 1 0.38 0.26 0
191 INT260080 Negative_regulation of Gene_expression of PTCH1 1 0.58 2.09 0
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