GO:0060042

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Name retina morphogenesis in camera-type eye
Categary Process
Go Slim No
Go Link GO:0060042
Unique Molecular Interactions 31
Total Molecular Interactions 45
Total Single Events 502
Pain Genes Associated 11

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for retina morphogenesis in camera-type eye. They are ordered first by their pain relevance and then by number of times they were reported for retina morphogenesis in camera-type eye. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT231533 IL4 Positive_regulation of LRP5 1 0.00 0.87 0.67
2 INT143619 Bhlhe22 Positive_regulation of Regulation of Msr1 1 0.40 0.93 0.46
3 INT309369 Ptf1a Positive_regulation of Pax2 1 0.10 0 0.3
4 INT335888 Lrp5 Negative_regulation of Gene_expression of Tph1 1 0.22 0.15 0.21
5 INT251665 LRP5 Negative_regulation of Ache 1 0.31 0.39 0.19
6 INT208207 Binding of Cadm1 and Pvrl3 1 0.12 1.06 0.12
7 INT167198 Binding of Prom1 and Ly6a 1 0.40 0 0.09
8 INT201173 Sox2 Positive_regulation of Localization of Ryr2 1 0.40 0.9 0.07
9 INT201172 Sox2 Positive_regulation of Localization of Ca2 1 0.47 0.9 0.07
10 INT355327 Binding of Nes and Prom1 1 0.11 1.49 0.06
11 INT213562 Ctnnd2 Regulation of Gene_expression of Sox2 1 0.35 0.07 0.05
12 INT254433 Binding of Lrp5 and Sost 2 0.39 1.51 0.03
13 INT167565 Binding of ERG and LRP5 1 0.02 0.94 0.03
14 INT254434 Binding of Lrp5 and Best1 3 0.29 2.53 0
15 INT286113 Binding of Fap and Rpe65 1 0.04 1.97 0
16 INT307602 Binding of ACHE and LRP5 1 0.01 0.17 0
17 INT342385 Positive_regulation of Binding of Lrp5 and Vdr 1 0.53 0.98 0
18 INT290590 Binding of Cdh5 and Prom1 1 0.05 0.08 0
19 INT302321 Negative_regulation of Binding of Lrp6 and SOST 1 0.16 0.26 0
20 INT302322 Negative_regulation of Binding of Lrp5 and SOST 1 0.16 0.26 0
21 INT260025 PROM1 Positive_regulation of Gene_expression of NES 1 0.56 0.74 0
22 INT286110 Binding of Rpe65 and Gopc 1 0.01 1.97 0
23 INT302320 Binding of Lrp6 and SOST 1 0.18 0.26 0
24 INT342381 Binding of Lrp5 and Vdr 1 0.55 0.97 0
25 INT335887 Akt1 Regulation of Lrp6 1 0.06 0.15 0
26 INT342382 Binding of Car1 and Lrp5 1 0.40 0.9 0
27 INT245722 Binding of Vsx2 and Mfrp 1 0.24 1.2 0
28 INT302319 Binding of Lrp5 and SOST 1 0.18 0.26 0
29 INT335883 Binding of Lrp6 and Wnt5a 1 0.27 0.08 0
30 INT335891 Binding of Dkk1 and Lrp5 1 0.39 0.57 0
31 INT260024 PROM1 Positive_regulation of NES 1 0.56 0.73 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for retina morphogenesis in camera-type eye. They are ordered first by their pain relevance and then by number of times they were reported in retina morphogenesis in camera-type eye. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT40368 Positive_regulation of LRP5 5 0.49 3.19 3.51
2 INT139366 Gene_expression of PROM1 98 0.77 67.84 3.39
3 INT117660 Gene_expression of Prom1 50 0.73 39.62 3.07
4 INT96575 Gene_expression of Bhlhe22 5 0.65 1.97 2.21
5 INT108519 Binding of Lrp6 8 0.44 1.47 1.19
6 INT104440 Localization of Bhlhe22 1 0.73 0.71 1.04
7 INT102739 Binding of Bhlhe22 3 0.36 0.95 0.83
8 INT72334 Negative_regulation of LRP5 7 0.35 1.71 0.81
9 INT40369 Gene_expression of LRP5 8 0.55 5.63 0.74
10 INT231558 Regulation of LRP5 2 0.24 1.02 0.68
11 INT185244 Gene_expression of Sox2 27 0.65 4.71 0.61
12 INT40367 Positive_regulation of Gene_expression of LRP5 1 0.09 0 0.57
13 INT88588 Positive_regulation of Bhlhe22 2 0.67 1.28 0.56
14 INT351538 Binding of Prom1 8 0.38 4.44 0.49
15 INT166278 Positive_regulation of PROM1 14 0.49 7.95 0.48
16 INT185255 Positive_regulation of Sox2 3 0.26 1.22 0.42
17 INT96573 Transcription of Bhlhe22 1 0.67 0.29 0.42
18 INT232506 Positive_regulation of Gene_expression of PROM1 6 0.50 3.25 0.34
19 INT202646 Gene_expression of Ptf1a 10 0.48 0.46 0.29
20 INT297804 Regulation of Lrp5 6 0.60 2.31 0.27
21 INT335875 Regulation of Lrp6 1 0.57 0.43 0.27
22 INT254427 Binding of Lrp5 10 0.48 5.43 0.26
23 INT201143 Regulation of Sox2 6 0.44 2.71 0.26
24 INT351540 Negative_regulation of Gene_expression of Prom1 4 0.53 3.44 0.26
25 INT334543 Negative_regulation of Positive_regulation of LRP5 1 0.23 1.81 0.25
26 INT202632 Negative_regulation of Ptf1a 2 0.27 0 0.23
27 INT309358 Positive_regulation of Ptf1a 1 0.17 0 0.23
28 INT309357 Negative_regulation of Positive_regulation of Ptf1a 1 0.14 0 0.23
29 INT173655 Binding of LRP5 10 0.39 3.06 0.22
30 INT102740 Positive_regulation of Binding of Bhlhe22 1 0.49 0.38 0.2
31 INT260174 Gene_expression of Rpe65 29 0.78 4.2 0.19
32 INT167197 Positive_regulation of Prom1 4 0.46 0.76 0.19
33 INT254429 Negative_regulation of Lrp5 4 0.57 1.95 0.18
34 INT351537 Regulation of Prom1 1 0.41 1.44 0.17
35 INT335861 Localization of Lrp6 1 0.69 0.54 0.17
36 INT232511 Regulation of PROM1 7 0.27 4.91 0.16
37 INT244784 Gene_expression of Vsx2 3 0.65 0.78 0.13
38 INT232505 Regulation of Gene_expression of PROM1 3 0.27 2.12 0.11
39 INT201144 Regulation of Gene_expression of Sox2 3 0.44 0.82 0.11
40 INT201140 Transcription of Sox2 4 0.67 1.31 0.1
41 INT186997 Negative_regulation of Gene_expression of PROM1 4 0.26 2.72 0.08
42 INT351541 Regulation of Gene_expression of Prom1 1 0.41 0.46 0.08
43 INT139363 Negative_regulation of PROM1 2 0.40 2.24 0.07
44 INT254426 Gene_expression of Lrp5 5 0.67 3.28 0.06
45 INT208205 Binding of Pvrl3 1 0.11 0.53 0.06
46 INT335865 Positive_regulation of Phosphorylation of Lrp6 1 0.64 0.46 0.05
47 INT335862 Phosphorylation of Lrp6 1 0.76 0.37 0.05
48 INT185260 Positive_regulation of Positive_regulation of Sox2 1 0.15 0 0.05
49 INT264714 Positive_regulation of Gene_expression of Prom1 4 0.46 1.67 0.04
50 INT213537 Positive_regulation of Gene_expression of Sox2 3 0.48 1.34 0.04
51 INT213528 Negative_regulation of Gene_expression of Sox2 1 0.30 0.07 0.04
52 INT242172 Protein_catabolism of LRP5 1 0.64 0.06 0.04
53 INT280925 Negative_regulation of Prom1 3 0.53 3.91 0.03
54 INT232512 Negative_regulation of Positive_regulation of PROM1 1 0.26 0.24 0.03
55 INT319131 Positive_regulation of Lrp5 1 0.43 0.36 0.03
56 INT260030 Localization of PROM1 5 0.70 4.36 0
57 INT201142 Negative_regulation of Sox2 4 0.57 0.59 0
58 INT201141 Binding of Sox2 3 0.36 0.53 0
59 INT297757 Transcription of Lrp5 2 0.68 0.82 0
60 INT245717 Binding of Vsx2 2 0.27 1.2 0
61 INT297820 Regulation of Transcription of Lrp5 2 0.44 0.83 0
62 INT307613 Phosphorylation of LRP5 1 0.08 0.1 0
63 INT327892 Phosphorylation of PROM1 1 0.21 0.99 0
64 INT260171 Regulation of Gene_expression of Rpe65 1 0.39 0 0
65 INT338714 Binding of PROM1 1 0.21 2.04 0
66 INT202647 Negative_regulation of Gene_expression of Ptf1a 1 0.36 0.28 0
67 INT173644 Negative_regulation of Gene_expression of LRP5 1 0.15 0.59 0
68 INT260173 Localization of Rpe65 1 0.66 0.18 0
69 INT260169 Positive_regulation of Rpe65 1 0.44 0.07 0
70 INT335872 Positive_regulation of Gene_expression of Lrp6 1 0.46 0.18 0
71 INT266215 Positive_regulation of Gene_expression of Vsx2 1 0.42 0.34 0
72 INT308293 Positive_regulation of Positive_regulation of PROM1 1 0.23 0.45 0
73 INT202630 Transcription of Ptf1a 1 0.43 0 0
74 INT342375 Positive_regulation of Binding of Lrp5 1 0.46 0.85 0
75 INT201146 Negative_regulation of Binding of Sox2 1 0.41 0.28 0
76 INT302465 Localization of LRP5 1 0.61 0 0
77 INT202637 Regulation of Ptf1a 1 0.17 0.17 0
78 INT260168 Negative_regulation of Gene_expression of Rpe65 1 0.43 0.22 0
79 INT202624 Positive_regulation of Gene_expression of Ptf1a 1 0.31 0 0
80 INT201139 Localization of Sox2 1 0.73 0.15 0
81 INT260027 Transcription of PROM1 1 0.71 0.73 0
82 INT347117 Negative_regulation of Binding of Lrp6 1 0.28 0.5 0
83 INT335866 Regulation of Transcription of Lrp6 1 0.42 0.25 0
84 INT260166 Positive_regulation of Gene_expression of Rpe65 1 0.61 0.43 0
85 INT307611 Positive_regulation of Phosphorylation of LRP5 1 0.05 0.1 0
86 INT335881 Gene_expression of Lrp6 1 0.62 0.09 0
87 INT335873 Transcription of Lrp6 1 0.64 0.25 0
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