GO:0060053

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Name neurofilament cytoskeleton
Categary Component
Go Slim No
Go Link GO:0060053
Unique Molecular Interactions 52
Total Molecular Interactions 94
Total Single Events 335
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for neurofilament cytoskeleton. They are ordered first by their pain relevance and then by number of times they were reported for neurofilament cytoskeleton. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT229497 Binding of Vim and Ndel1 1 0.33 3.5 2.81
2 INT229496 Binding of Ndel1 and Gopc 1 0.08 2.05 1.36
3 INT253836 Cck Regulation of DST 1 0.03 0.42 0.95
4 INT89012 DST Positive_regulation of Insr 1 0.01 0.86 0.59
5 INT253835 Binding of DST and Fos 1 0.02 0 0.55
6 INT229507 Binding of Nefl and Ndel1 1 0.09 2.01 0.43
7 INT244421 Binding of DST and Ctss 1 0.02 0.42 0.41
8 INT67633 Binding of DST and Gabrd 1 0.03 0 0.41
9 INT25526 Dst Regulation of Gh 1 0.00 0.26 0.34
10 INT52333 Fos Regulation of Gene_expression of Synm 1 0.02 0 0.33
11 INT343569 Negative_regulation of Synm Positive_regulation of Gpt 1 0.01 0.96 0.29
12 INT244422 Binding of DST and Fig4 1 0.01 0.42 0.29
13 INT343571 Synm Positive_regulation of ALPP 1 0.01 1.28 0.28
14 INT343570 Synm Positive_regulation of Gpt 1 0.01 1.28 0.28
15 INT343573 Synm Positive_regulation of SLC17A5 1 0.17 1.28 0.28
16 INT291641 Binding of DST and ESRRG 1 0.16 1.8 0.28
17 INT274005 KCNK3 Positive_regulation of SYNM 1 0.06 0 0.23
18 INT52355 Cfp Negative_regulation of Ndel1 1 0.34 0.16 0.21
19 INT229513 Positive_regulation of Binding of Ndel1 and Gopc 1 0.09 0.2 0.2
20 INT291642 Binding of DST and GGT1 1 0.00 1.4 0.19
21 INT214170 Binding of DST and Lep 1 0.02 0.17 0.18
22 INT262359 Binding of DISC1 and NDEL1 1 0.04 0.56 0.18
23 INT274353 DST Regulation of Gopc 1 0.00 0 0.17
24 INT291644 Binding of DST and ESR1 1 0.05 0.84 0.14
25 INT229506 Negative_regulation of Binding of Ndel1 and Gopc 1 0.08 0.35 0.09
26 INT214168 Msx1 Positive_regulation of Gene_expression of DST 1 0.00 0.13 0.09
27 INT229504 Negative_regulation of Binding of Nefl and Ndel1 1 0.08 0.33 0.09
28 INT214166 DST Negative_regulation of Gene_expression of Npy 1 0.02 0.07 0.09
29 INT311083 DST Regulation of FOS 1 0.03 0.15 0.08
30 INT229493 Binding of Ndel1 and Disc1 1 0.13 0.68 0.06
31 INT135641 Binding of Dst and Ina 1 0.35 0.34 0.06
32 INT229505 Ndel1 Negative_regulation of Vim 1 0.29 0.14 0.04
33 INT311082 DST Regulation of MAPK8 1 0.02 0.07 0.04
34 INT229494 Binding of Ndel1 and Tsp1 1 0.03 0.24 0.04
35 INT229503 Binding of Ndel1 and Fez1 1 0.15 0.34 0.03
36 INT214167 Binding of DST and Pomc 1 0.03 0.22 0.03
37 INT214171 Binding of DST and Cartpt 1 0.01 0.21 0.03
38 INT222140 Binding of Cdh2 and Synm 1 0.00 0 0
39 INT229511 Ndel1 Regulation of Binding of Nefl 1 0.09 0.31 0
40 INT199367 DST Regulation of Igf2 1 0.03 1.03 0
41 INT282331 Binding of DST and Gopc 1 0.01 0.61 0
42 INT199368 DST Positive_regulation of Gene_expression of Igf2 1 0.04 1.51 0
43 INT199371 DST Regulation of Transcription of Igf2 1 0.05 1.47 0
44 INT282330 Binding of DST and Arc 1 0.04 1.1 0
45 INT199366 DST Positive_regulation of Macf1 1 0.01 1.14 0
46 INT343572 Negative_regulation of Synm Positive_regulation of SLC17A5 1 0.16 0.44 0
47 INT199370 DST Regulation of Gene_expression of Igf2 1 0.02 1.07 0
48 INT199369 DST Regulation of Igf1 1 0.02 0.8 0
49 INT222141 Binding of Serpina3f and Synm 1 0.03 0 0
50 INT282329 Regulation of Binding of DST and Arc 1 0.03 0.35 0
51 INT291643 Binding of DST and INS 1 0.07 0.38 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for neurofilament cytoskeleton. They are ordered first by their pain relevance and then by number of times they were reported in neurofilament cytoskeleton. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT67101 Gene_expression of DST 47 0.54 25.92 9.59
2 INT6758 Positive_regulation of Synm 12 0.43 2.57 6.83
3 INT38644 Positive_regulation of DST 30 0.53 12.48 6.59
4 INT11761 Negative_regulation of DST 13 0.42 7.66 3.65
5 INT102076 Regulation of DST 15 0.22 10 3.5
6 INT316829 Negative_regulation of SYNM 4 0.54 3.31 3.32
7 INT45303 Binding of SYNM 4 0.40 2.14 3.07
8 INT200833 Gene_expression of Ndel1 2 0.73 5.56 2.9
9 INT274527 Regulation of SYNM 3 0.20 2.68 2.7
10 INT242107 Positive_regulation of SYNM 8 0.38 2.82 2.39
11 INT6759 Regulation of Positive_regulation of Synm 1 0.21 0 2.19
12 INT229467 Binding of Ndel1 1 0.45 2.71 2
13 INT229463 Positive_regulation of Ndel1 1 0.66 1.87 1.64
14 INT134673 Gene_expression of SYNM 16 0.75 2.72 1.62
15 INT135640 Negative_regulation of Dst 5 0.57 2.25 1.56
16 INT274526 Localization of SYNM 1 0.33 1.36 1.34
17 INT38645 Negative_regulation of Positive_regulation of DST 3 0.29 1.05 1.29
18 INT101027 Binding of DST 20 0.41 10.9 1.17
19 INT229466 Localization of Ndel1 1 0.76 1.32 1.1
20 INT52330 Gene_expression of Synm 4 0.45 0.72 1
21 INT103944 Negative_regulation of Synm 3 0.41 2.17 0.83
22 INT95190 Gene_expression of NDEL1 1 0.29 0 0.81
23 INT52332 Binding of Synm 2 0.30 0.59 0.75
24 INT35943 Positive_regulation of NDEL1 1 0.31 0 0.62
25 INT244420 Positive_regulation of Gene_expression of DST 4 0.41 2.05 0.59
26 INT35942 Negative_regulation of NDEL1 1 0.27 0 0.47
27 INT229481 Positive_regulation of Gene_expression of Ndel1 1 0.47 0.73 0.47
28 INT214136 Localization of DST 7 0.65 2.59 0.42
29 INT95191 Protein_catabolism of NDEL1 1 0.22 0 0.39
30 INT103945 Regulation of Synm 1 0.37 0.59 0.39
31 INT135638 Binding of Dst 4 0.36 2.76 0.38
32 INT200744 Regulation of Gene_expression of DST 5 0.20 2.64 0.36
33 INT229482 Positive_regulation of Binding of Ndel1 1 0.47 0.37 0.32
34 INT75628 Gene_expression of Dst 4 0.60 0.78 0.31
35 INT229459 Negative_regulation of Gene_expression of Ndel1 1 0.41 0.75 0.29
36 INT229473 Transcription of Ndel1 1 0.65 0.49 0.29
37 INT75626 Positive_regulation of Dst 2 0.50 0.52 0.23
38 INT229476 Regulation of Ndel1 1 0.43 0.6 0.23
39 INT282322 Regulation of Binding of DST 1 0.04 0.35 0.22
40 INT52354 Regulation of Ndel1 1 0.19 0.16 0.21
41 INT52351 Positive_regulation of Ndel1 1 0.50 0.16 0.21
42 INT135637 Regulation of Dst 3 0.44 1.03 0.2
43 INT274007 Positive_regulation of Gene_expression of SYNM 2 0.27 0.12 0.2
44 INT86687 Gene_expression of Ndel1 1 0.25 0 0.19
45 INT343567 Localization of Synm 1 0.25 1.04 0.18
46 INT262360 Binding of NDEL1 1 0.04 0.56 0.18
47 INT200745 Negative_regulation of Gene_expression of DST 3 0.10 2.75 0.17
48 INT75625 Localization of Dst 1 0.75 0.15 0.13
49 INT242106 Positive_regulation of Positive_regulation of SYNM 1 0.24 0.54 0.12
50 INT221970 Phosphorylation of NDEL1 1 0.12 0.39 0.09
51 INT229472 Positive_regulation of Transcription of Ndel1 1 0.44 0.31 0.09
52 INT214135 Transcription of DST 1 0.05 0.41 0.06
53 INT244419 Positive_regulation of Binding of DST 1 0.02 0.15 0.06
54 INT326581 Positive_regulation of Gene_expression of Dst 1 0.36 0.17 0.05
55 INT229478 Negative_regulation of Ndel1 1 0.41 0.24 0.03
56 INT52352 Negative_regulation of Ndel1 1 0.42 0.12 0.03
57 INT134675 Negative_regulation of Gene_expression of SYNM 1 0.42 0.22 0
58 INT291645 Positive_regulation of Localization of DST 1 0.41 0.49 0
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