GO:0060058

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Name positive regulation of apoptosis involved in mammary gland involution
Categary Process
Go Slim No
Go Link GO:0060058
Unique Molecular Interactions 90
Total Molecular Interactions 103
Total Single Events 1096
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of apoptosis involved in mammary gland involution. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of apoptosis involved in mammary gland involution. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT296793 Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.75 0.65
2 INT296790 Tlr9 Regulation of Bax 1 0.14 0.76 0.65
3 INT296791 Positive_regulation of Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.8 0.65
4 INT112699 Bid Regulation of Bax 1 0.25 0.51 0.61
5 INT238638 Gopc Negative_regulation of Gene_expression of Bax 1 0.04 0.85 0.45
6 INT155061 Stat3 Negative_regulation of Bax 1 0.22 3.71 0.34
7 INT130803 MC1R Regulation of Positive_regulation of Cdkn2a 1 0.17 0.82 0.34
8 INT335027 Binding of Vdr and Fgf23 1 0.24 0.34 0.29
9 INT262151 Vdr Regulation of Cyp24a1 1 0.24 0.24 0.23
10 INT155063 Csf2 Negative_regulation of Gene_expression of Bax 1 0.27 1.46 0.18
11 INT335018 Vdr Positive_regulation of Gene_expression of Fgf23 1 0.44 0.36 0.17
12 INT155066 Csf2 Negative_regulation of Bax 1 0.12 1.89 0.17
13 INT349475 Regulation of Bax Regulation of Bcl2 1 0.07 1.35 0.17
14 INT336891 Epo Negative_regulation of Transcription of Bax 1 0.10 0.68 0.16
15 INT136855 Arf5 Positive_regulation of Cdkn2a 1 0.07 1.8 0.15
16 INT349476 Bax Regulation of Bcl2 1 0.07 1.33 0.15
17 INT314856 Binding of Cdc7 and Cdkn2a 1 0.28 1.34 0.14
18 INT314852 Binding of Cdkn2a and Tgfbr3 1 0.28 1.15 0.14
19 INT273040 Vip Regulation of Bax 1 0.23 1.69 0.13
20 INT273041 Adcyap1 Regulation of Bax 1 0.21 1.69 0.13
21 INT226192 Protein_catabolism of Bax Positive_regulation of Gtf3a 1 0.00 0.53 0.12
22 INT333765 Positive_regulation of Vdr Regulation of Gene_expression of Ccr6 1 0.21 0.48 0.12
23 INT285030 Binding of Bax and Slc25a4 1 0.03 0.84 0.11
24 INT166723 Binding of Vdr and Rxrb 1 0.11 0.31 0.09
25 INT166724 Binding of Vdr and Rxra 1 0.28 0.32 0.09
26 INT262216 Positive_regulation of Nr1i2 Positive_regulation of Gene_expression of Vdr 1 0.29 0.44 0.08
27 INT136856 Cdkn2a Positive_regulation of Arf5 1 0.01 0.9 0.08
28 INT285032 Bnip3 Positive_regulation of Bax 1 0.28 0.77 0.07
29 INT340401 Positive_regulation of Bax Positive_regulation of Binding of Hrk 1 0.01 0.79 0.07
30 INT340395 Binding of Bax and Tg(CAG-EGFP)D4Nagy 1 0.02 0.43 0.07
31 INT204073 Binding of Cdkn2a and Cdk4 1 0.02 0.78 0.05
32 INT204072 Binding of Cdkn2a and Cdk6 1 0.02 0.78 0.05
33 INT262196 Nr1i2 Negative_regulation of Vdr 1 0.27 0.14 0.04
34 INT262166 Binding of Nr1i2 and Vdr 1 0.23 0.14 0.04
35 INT340394 Binding of Bax and Bbc3 1 0.01 0.36 0.04
36 INT262154 Vdr Negative_regulation of Cyp24a1 1 0.16 0.14 0.04
37 INT172902 Binding of Bax and Bcl2 5 0.30 3.19 0.03
38 INT297737 Cbr1 Positive_regulation of Bax 1 0.06 0.53 0.03
39 INT333259 Bcl2 Regulation of Bax 1 0.03 0.32 0.03
40 INT224676 Binding of Bax and Mcl1 1 0.01 1.09 0.03
41 INT224690 Mcl1 Regulation of Bax 1 0.00 1.09 0.03
42 INT341376 Sod2 Regulation of Bax 1 0.09 0.99 0.03
43 INT172906 Binding of Bax and Bcl2l1 2 0.16 2.03 0
44 INT225228 Binding of Cdk4 and Cdkn2a 1 0.21 1.24 0
45 INT215707 Cdkn2a Negative_regulation of Cdkn1b 1 0.01 0 0
46 INT342385 Positive_regulation of Binding of Lrp5 and Vdr 1 0.53 0.98 0
47 INT285029 Binding of Bax and Bcl2l1 1 0.25 0.1 0
48 INT330047 Binding of Bax and Bcl2l11 1 0.13 0.62 0
49 INT191058 Binding of Bcl2 and Positive_regulation of Gene_expression of Bax 1 0.21 0.49 0
50 INT342378 Binding of Vdr and Best1 1 0.05 0.4 0
51 INT242483 Negative_regulation of Ciapin1 Negative_regulation of Positive_regulation of Bax 1 0.17 1.76 0
52 INT136914 Mapk8 Positive_regulation of Localization of Bax 1 0.51 0.12 0
53 INT225229 Binding of Cdk6 and Cdkn2a 1 0.19 1.25 0
54 INT353437 Negative_regulation of Trp53 Positive_regulation of Gene_expression of Cdkn2a 1 0.24 0.59 0
55 INT322664 Prdm8 Positive_regulation of Gene_expression of Bax 1 0.01 1.1 0
56 INT285028 Binding of Bcl2 and Bax 1 0.32 0.1 0
57 INT229821 Fos Positive_regulation of Bax 1 0.15 0.27 0
58 INT342381 Binding of Lrp5 and Vdr 1 0.55 0.97 0
59 INT309517 Binding of Bax and Xrcc6 1 0.15 0.5 0
60 INT201761 BIK Positive_regulation of Positive_regulation of Bax 1 0.01 0.43 0
61 INT330052 Binding of Bax and Bid 1 0.15 0.62 0
62 INT322662 Binding of Bax and Pbrm1 1 0.08 0.9 0
63 INT172908 Binding of Bad and Bax 1 0.01 1.34 0
64 INT330057 Bid Positive_regulation of Bax 1 0.19 0.62 0
65 INT342388 Binding of CALCR and Vdr 1 0.12 0.83 0
66 INT215699 Cdkn2a Negative_regulation of Cdkn1c 1 0.01 0 0
67 INT313426 Positive_regulation of Ppp2ca Positive_regulation of Bax 1 0.46 0.36 0
68 INT267252 Bax Regulation of Bak1 1 0.05 1.09 0
69 INT201765 Binding of BCL2L1 and Bax 1 0.00 0.28 0
70 INT215696 Cdkn2a Negative_regulation of Kras 1 0.00 0 0
71 INT201763 BID Positive_regulation of Positive_regulation of Bax 1 0.01 0.43 0
72 INT242476 Negative_regulation of Ciapin1 Positive_regulation of Bax 1 0.19 1.29 0
73 INT322670 Prdm8 Positive_regulation of Bax 1 0.01 1.1 0
74 INT225578 Binding of Vdr and Pprc1 1 0.00 0 0
75 INT275753 xn Regulation of Bax 1 0.05 1.31 0
76 INT333681 Trp53 Regulation of Negative_regulation of Bax 1 0.15 1.17 0
77 INT334718 Binding of NOS1 and Bax 1 0.02 0.87 0
78 INT330054 Bcl2l11 Positive_regulation of Bax 1 0.25 0.62 0
79 INT254090 EPO Negative_regulation of Gene_expression of Bax 1 0.10 0.63 0
80 INT340400 Binding of Bax and Mom6 1 0.04 0.28 0
81 INT275746 Binding of xn and Bax 1 0.05 2.57 0
82 INT340399 Binding of Bak1 and Bax 1 0.12 0.91 0
83 INT309518 Negative_regulation of Binding of Bax and Xrcc6 1 0.16 0.25 0
84 INT201768 BCL2L11 Positive_regulation of Positive_regulation of Bax 1 0.00 0.43 0
85 INT201743 Bad Positive_regulation of Positive_regulation of Bax 1 0.00 0.43 0
86 INT136915 RYBP Positive_regulation of Localization of Bax 1 0.01 0.12 0
87 INT322660 Binding of Bax and Prdm8 1 0.01 0.89 0
88 INT100425 Bax Regulation of Pcbd1 1 0.06 0.06 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of apoptosis involved in mammary gland involution. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of apoptosis involved in mammary gland involution. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT100423 Gene_expression of Bax 141 0.75 98.43 24.48
2 INT109511 Gene_expression of Bax 133 0.78 113.22 14.36
3 INT102110 Positive_regulation of Gene_expression of Bax 42 0.67 35.77 9.51
4 INT102106 Positive_regulation of Bax 48 0.67 30.62 9.28
5 INT102107 Negative_regulation of Gene_expression of Bax 30 0.57 29.48 7.33
6 INT98837 Positive_regulation of Bax 72 0.61 63.14 6.41
7 INT13295 Positive_regulation of Cdkn2a 18 0.68 13.02 5.47
8 INT145929 Regulation of Bax 20 0.60 18.12 5.35
9 INT109513 Positive_regulation of Gene_expression of Bax 37 0.67 29.52 5.06
10 INT99504 Negative_regulation of Bax 19 0.56 8.89 4.44
11 INT123752 Regulation of Bax 19 0.60 16.45 4
12 INT112692 Localization of Bax 31 0.80 20.97 3.98
13 INT78248 Negative_regulation of Cdkn2a 17 0.59 15.15 2.8
14 INT160633 Gene_expression of Vdr 21 0.77 10.01 2.73
15 INT102146 Phosphorylation of Bax 4 0.66 3.48 2.35
16 INT154970 Localization of Bax 15 0.74 11.12 2.11
17 INT94772 Gene_expression of Cdkn2a 14 0.75 8.25 2.04
18 INT98836 Transcription of Bax 6 0.69 5.04 1.96
19 INT134442 Transcription of Bax 14 0.67 7.6 1.9
20 INT135540 Negative_regulation of Bax 16 0.48 11.8 1.89
21 INT134443 Binding of Bax 10 0.47 5.62 1.84
22 INT104883 Positive_regulation of Positive_regulation of Bax 4 0.45 4.05 1.74
23 INT146785 Positive_regulation of Localization of Bax 7 0.69 6.16 1.47
24 INT109512 Negative_regulation of Gene_expression of Bax 12 0.42 8.04 1.44
25 INT112695 Negative_regulation of Protein_catabolism of Bax 3 0.36 1.72 1.3
26 INT154969 Positive_regulation of Localization of Bax 4 0.64 3.42 1.27
27 INT112693 Protein_catabolism of Bax 5 0.74 3.17 1.2
28 INT141189 Negative_regulation of Transcription of Bax 1 0.41 1.42 1.14
29 INT112214 Gene_expression of Vdr 4 0.33 3.59 1.11
30 INT42104 Regulation of Cdkn2a 4 0.44 5.67 1.06
31 INT175507 Regulation of Gene_expression of Bax 13 0.50 10.91 0.95
32 INT144697 Regulation of Gene_expression of Bax 8 0.37 9.5 0.81
33 INT144429 Positive_regulation of Cdkn2a 7 0.58 4.05 0.78
34 INT129115 Negative_regulation of Cdkn2a 16 0.50 17.03 0.76
35 INT262107 Binding of Vdr 9 0.48 6.56 0.71
36 INT262060 Positive_regulation of Vdr 8 0.58 2.84 0.67
37 INT177886 Positive_regulation of Gene_expression of Cdkn2a 3 0.67 3.42 0.62
38 INT124270 Positive_regulation of Gene_expression of Vdr 2 0.29 1.1 0.58
39 INT242011 Localization of Cdkn2a 4 0.73 2.49 0.54
40 INT144701 Gene_expression of Cdkn2a 15 0.75 8.42 0.53
41 INT176242 Binding of Bax 10 0.42 10.18 0.52
42 INT144431 Positive_regulation of Transcription of Cdkn2a 1 0.41 1.11 0.51
43 INT144426 Transcription of Cdkn2a 1 0.42 1.11 0.51
44 INT102108 Protein_catabolism of Bax 8 0.64 5.69 0.48
45 INT134446 Positive_regulation of Binding of Bax 1 0.49 0.72 0.48
46 INT112215 Binding of Vdr 4 0.31 2.43 0.44
47 INT160642 Positive_regulation of Gene_expression of Vdr 5 0.62 1.61 0.42
48 INT42105 Regulation of Positive_regulation of Cdkn2a 1 0.44 0.33 0.42
49 INT152059 Regulation of Transcription of Bax 1 0.26 0.07 0.42
50 INT135802 Positive_regulation of Negative_regulation of Bax 2 0.41 0.57 0.4
51 INT204069 Negative_regulation of Positive_regulation of Bax 5 0.31 3.08 0.34
52 INT169538 Negative_regulation of Localization of Bax 3 0.49 1.41 0.34
53 INT184482 Positive_regulation of Positive_regulation of Bax 5 0.41 4.7 0.33
54 INT221191 Negative_regulation of Localization of Bax 4 0.38 2.85 0.33
55 INT262063 Localization of Vdr 3 0.75 1.76 0.33
56 INT196323 Localization of Cdkn2a 8 0.73 9.1 0.32
57 INT228477 Positive_regulation of Gene_expression of Cdkn2a 2 0.11 1.3 0.29
58 INT102111 Positive_regulation of Protein_catabolism of Bax 2 0.45 1.14 0.27
59 INT102637 Positive_regulation of Vdr 3 0.48 2.82 0.24
60 INT135543 Negative_regulation of Positive_regulation of Bax 5 0.30 6.4 0.23
61 INT262040 Negative_regulation of Gene_expression of Vdr 1 0.25 0.26 0.21
62 INT241687 Binding of Cdkn2a 5 0.31 5.26 0.18
63 INT300463 Regulation of Regulation of Bax 1 0.29 1.33 0.18
64 INT160641 Transcription of Vdr 5 0.71 3.1 0.16
65 INT225216 Negative_regulation of Negative_regulation of Cdkn2a 1 0.42 3.16 0.15
66 INT333738 Regulation of Positive_regulation of Vdr 1 0.38 0.48 0.12
67 INT336888 Negative_regulation of Transcription of Bax 1 0.07 0.68 0.11
68 INT112001 Binding of Cdkn2a 1 0.24 0.35 0.1
69 INT304137 Regulation of Localization of Bax 2 0.24 1.7 0.09
70 INT273604 Regulation of Negative_regulation of Cdkn2a 1 0.12 0.68 0.09
71 INT307466 Positive_regulation of Phosphorylation of Bax 1 0.15 0.76 0.07
72 INT211082 Regulation of Positive_regulation of Vdr 1 0.30 1.18 0.07
73 INT211079 Positive_regulation of Positive_regulation of Vdr 1 0.33 0.59 0.05
74 INT268622 Regulation of Negative_regulation of Bax 1 0.12 0.81 0.05
75 INT315215 Negative_regulation of Binding of Cdkn2a 1 0.35 0.11 0.05
76 INT309494 Negative_regulation of Binding of Bax 2 0.38 1.31 0.04
77 INT262079 Negative_regulation of Vdr 2 0.42 0.71 0.04
78 INT340387 Regulation of Positive_regulation of Bax 1 0.27 0.61 0.04
79 INT211080 Negative_regulation of Positive_regulation of Vdr 1 0.29 0.6 0.04
80 INT340390 Regulation of Binding of Bax 1 0.54 0.59 0.04
81 INT123525 Phosphorylation of Bax 3 0.41 1.18 0.03
82 INT176247 Positive_regulation of Phosphorylation of Bax 1 0.12 0.42 0.03
83 INT94773 Negative_regulation of Gene_expression of Cdkn2a 3 0.41 0.65 0
84 INT282090 Regulation of Cdkn2a 2 0.33 2.02 0
85 INT308355 Negative_regulation of Gene_expression of Cdkn2a 2 0.48 1.42 0
86 INT288196 Negative_regulation of Transcription of Vdr 1 0.23 0 0
87 INT330041 Positive_regulation of Regulation of Bax 1 0.29 1.63 0
88 INT333213 Regulation of Transcription of Bax 1 0.11 0.14 0
89 INT140704 Transcription of Vdr 1 0.12 0.38 0
90 INT322640 Positive_regulation of Binding of Bax 1 0.12 0.88 0
91 INT247424 Transcription of Cdkn2a 1 0.47 0.82 0
92 INT342376 Positive_regulation of Binding of Vdr 1 0.46 0.86 0
93 INT234056 Positive_regulation of Transcription of Bax 1 0.35 0.36 0
94 INT160644 Positive_regulation of Transcription of Vdr 1 0.62 0 0
95 INT247425 Regulation of Transcription of Cdkn2a 1 0.18 0.82 0
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