GO:0060068

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Name vagina development
Categary Process
Go Slim No
Go Link GO:0060068
Unique Molecular Interactions 398
Total Molecular Interactions 489
Total Single Events 4978
Pain Genes Associated 20

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for vagina development. They are ordered first by their pain relevance and then by number of times they were reported for vagina development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT108810 Esr1 Positive_regulation of Binding of Oprm1 1 0.51 1.79 3.22
2 INT158079 Binding of Esr1 and Gper 1 0.31 0.97 1.35
3 INT222182 Binding of ESR1 and HLA-DRB2 1 0.00 3.1 1.35
4 INT150890 Binding of Esr1 and Esr2 2 0.52 2.06 1.31
5 INT278292 Binding of CRP and ESR1 6 0.09 10.92 0.96
6 INT108811 Esr2 Positive_regulation of Binding of Oprm1 1 0.46 0.44 0.79
7 INT108812 Esr1 Positive_regulation of Positive_regulation of Oprm1 1 0.42 0.38 0.78
8 INT257745 SAGE1 Positive_regulation of AXL 1 0.07 1.96 0.69
9 INT38057 Binding of Crp and Esr1 2 0.04 1.21 0.65
10 INT296793 Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.75 0.65
11 INT296790 Tlr9 Regulation of Bax 1 0.14 0.76 0.65
12 INT296791 Positive_regulation of Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.8 0.65
13 INT309158 Binding of Esr1 and Dlat 1 0.04 1.39 0.61
14 INT112699 Bid Regulation of Bax 1 0.25 0.51 0.61
15 INT109802 Binding of Esr2 and Oprl1 1 0.22 0.1 0.59
16 INT341594 Binding of ESR1 and HLA-B 1 0.01 0.72 0.57
17 INT150833 Esr1 Positive_regulation of Localization of Prkce 1 0.08 0.29 0.51
18 INT291556 Binding of ESR1 and Sec22b 2 0.00 0.86 0.5
19 INT154014 Binding of Esr1 and Gabrg1 1 0.07 0.07 0.5
20 INT147179 Esr1 Regulation of Gene_expression of Penk 1 0.01 0.68 0.46
21 INT41174 Bak1 Regulation of Localization of Prl 1 0.02 0 0.46
22 INT238638 Gopc Negative_regulation of Gene_expression of Bax 1 0.04 0.85 0.45
23 INT323840 Binding of Esr1 and Il1 1 0.04 0.9 0.42
24 INT209231 Tg(Ngf)47Kma Regulation of Tyro3 1 0.03 0 0.41
25 INT261374 Nsdhl Regulation of Esr2 1 0.05 0.76 0.41
26 INT261370 Nsdhl Regulation of Esr1 1 0.01 0.75 0.41
27 INT117361 Binding of Esr1 and sea 1 0.02 1.38 0.38
28 INT199974 ESR1 Negative_regulation of Gene_expression of ITGB3BP 1 0.05 0.47 0.38
29 INT197591 Esr1 Regulation of Pgr 1 0.04 0 0.38
30 INT117359 Binding of Esr1 and Wbc1 1 0.00 1.38 0.37
31 INT245328 Binding of Esr2 and Pgr 1 0.03 0.41 0.37
32 INT291555 Binding of ESR1 and Dlat 1 0.01 0.6 0.35
33 INT155061 Stat3 Negative_regulation of Bax 1 0.22 3.71 0.34
34 INT291554 Binding of ESR1 and St8sia2 1 0.01 0.49 0.33
35 INT128756 Binding of Esr1 and Foxc1 1 0.01 0.43 0.32
36 INT309156 Esr1 Regulation of Gene_expression of Dlat 1 0.05 1.06 0.3
37 INT222301 Binding of ERBB2 and ESR1 5 0.36 5.07 0.29
38 INT158734 Esr1 Regulation of Esrrb 1 0.00 0.28 0.29
39 INT158733 Esr1 Regulation of Plxna3 1 0.03 0.27 0.29
40 INT162599 Wnt5a Regulation of Gene_expression of IL4I1 1 0.00 0.1 0.28
41 INT185092 CRP Positive_regulation of ESR1 1 0.06 2.83 0.28
42 INT199978 ESR1 Regulation of ITGB3BP 1 0.03 0.39 0.28
43 INT71904 Binding of ESR1 and PGR 6 0.34 3.79 0.27
44 INT323152 Binding of DBT and ESR1 2 0.02 1.29 0.27
45 INT257740 SAGE1 Positive_regulation of Gene_expression of AXL 1 0.07 0.72 0.27
46 INT346195 AMELX Negative_regulation of ESR1 1 0.02 0.36 0.26
47 INT263587 Pdia3 Negative_regulation of Binding of Esr1 1 0.07 1.86 0.26
48 INT186783 Binding of ESR1 and NRIP1 1 0.31 0.79 0.25
49 INT199970 CYP19A1 Positive_regulation of Gene_expression of ESR1 1 0.06 0.72 0.25
50 INT182346 Binding of Cd3e and Esr1 1 0.06 1.26 0.25
51 INT182349 Binding of Ms4a1 and Esr1 1 0.04 1.26 0.25
52 INT199971 IL6 Positive_regulation of ESR1 1 0.08 0.84 0.24
53 INT309160 Binding of Esr1 and Edc4 1 0.03 0.34 0.24
54 INT197590 Esr2 Positive_regulation of Negative_regulation of Pgr 1 0.16 0 0.24
55 INT159163 Binding of Esr2 and Regulation of Gper 1 0.41 0.27 0.23
56 INT63203 INS Positive_regulation of ESR1 1 0.09 0.3 0.23
57 INT261389 Nsdhl Positive_regulation of Esr2 1 0.06 1.04 0.23
58 INT63198 POMC Positive_regulation of ESR1 1 0.14 0.3 0.23
59 INT270135 Binding of ESR1 and RALA 1 0.11 0.37 0.22
60 INT312517 Rapgef1 Negative_regulation of Rbp4 1 0.01 0.9 0.22
61 INT63192 PTH Positive_regulation of ESR1 1 0.20 0.29 0.22
62 INT308645 Binding of Esr1 and Itpr3 1 0.00 0 0.2
63 INT351086 Negative_regulation of ERBB2 Positive_regulation of Gene_expression of ESR1 1 0.10 0.75 0.19
64 INT351089 FOXO3 Positive_regulation of Gene_expression of ESR1 1 0.04 0.74 0.19
65 INT192219 CASP3 Regulation of ESR1 1 0.03 1.19 0.19
66 INT197618 Binding of Esr1 and Ppt1 1 0.01 0 0.18
67 INT173932 Binding of Esr1 and Il6 1 0.03 0.11 0.18
68 INT256586 Binding of RBP4 and TTR 1 0.07 1.92 0.18
69 INT155063 Csf2 Negative_regulation of Gene_expression of Bax 1 0.27 1.46 0.18
70 INT285026 Bak1 Regulation of Bcl2 1 0.09 0.71 0.17
71 INT285022 Regulation of Bak1 Regulation of Bcl2 1 0.09 0.71 0.17
72 INT155066 Csf2 Negative_regulation of Bax 1 0.12 1.89 0.17
73 INT349475 Regulation of Bax Regulation of Bcl2 1 0.07 1.35 0.17
74 INT285024 Bcl2 Regulation of Bak1 1 0.09 0.71 0.17
75 INT19042 ESR1 Positive_regulation of GGT5 1 0.03 0.6 0.17
76 INT19045 ESR1 Positive_regulation of Salpa1 1 0.02 0.6 0.17
77 INT336891 Epo Negative_regulation of Transcription of Bax 1 0.10 0.68 0.16
78 INT238825 LTF Regulation of Localization of RBP4 1 0.05 1.08 0.16
79 INT349476 Bax Regulation of Bcl2 1 0.07 1.33 0.15
80 INT309154 Esr1 Positive_regulation of Gsdmc 1 0.01 0.44 0.15
81 INT309155 Negative_regulation of Esr1 Positive_regulation of Gsdmc 1 0.01 0.45 0.15
82 INT181752 Binding of CPOX and ESR1 1 0.02 0.89 0.14
83 INT291644 Binding of DST and ESR1 1 0.05 0.84 0.14
84 INT273040 Vip Regulation of Bax 1 0.23 1.69 0.13
85 INT297312 Esr1 Positive_regulation of Scap 1 0.00 1.58 0.13
86 INT267973 Binding of CHKB and ESR1 1 0.02 1.67 0.13
87 INT86429 Binding of Hspb1 and Esr1 1 0.19 0.26 0.13
88 INT273041 Adcyap1 Regulation of Bax 1 0.21 1.69 0.13
89 INT287884 WNT5A Positive_regulation of THEMIS 1 0.00 0.08 0.13
90 INT226192 Protein_catabolism of Bax Positive_regulation of Gtf3a 1 0.00 0.53 0.12
91 INT236588 Binding of Esr1 and Ins1 1 0.05 0.73 0.12
92 INT101339 ZAK Regulation of Gene_expression of AXL 1 0.01 0.32 0.12
93 INT341827 Binding of ESR1 and TNC 1 0.14 0.63 0.11
94 INT280484 Bdnf Positive_regulation of Gene_expression of Lhx1 1 0.48 1.49 0.11
95 INT309371 Lhx1 Positive_regulation of Gene_expression of Pax2 1 0.08 0.07 0.11
96 INT285030 Binding of Bax and Slc25a4 1 0.03 0.84 0.11
97 INT341775 DBT Regulation of Binding of ESR1 1 0.02 0.1 0.11
98 INT252779 Binding of ESR1 and RAF1 1 0.01 2.03 0.11
99 INT220114 Tnfrsf1a Positive_regulation of Esr1 1 0.14 1.14 0.1
100 INT237819 Binding of Esr1 and soc 1 0.04 0 0.1
101 INT279407 Binding of ESR1 and IGKV2-19 1 0.02 0.4 0.1
102 INT233510 Wnt5a Positive_regulation of Gene_expression of Il12a 1 0.03 0.33 0.1
103 INT125000 Binding of Esr1 and Tas2r108 1 0.04 0.33 0.1
104 INT237812 Esr1 Positive_regulation of Positive_regulation of soc 1 0.05 0.6 0.1
105 INT201747 Itpr3 Positive_regulation of Localization of Esr1 2 0.03 1.19 0.09
106 INT308662 Binding of Esr1 and Fdft1 1 0.00 0.05 0.09
107 INT232559 Map3k1 Positive_regulation of Esr1 1 0.19 0.26 0.09
108 INT261396 Nsdhl Positive_regulation of Transcription of Esr1 1 0.02 2.1 0.09
109 INT341776 ESR1 Positive_regulation of Gene_expression of SLC6A3 1 0.06 0.08 0.09
110 INT232557 Erbb2 Positive_regulation of Esr1 1 0.23 0.26 0.09
111 INT204300 Bcl2 Negative_regulation of Positive_regulation of Bak1 1 0.02 1.13 0.09
112 INT52836 ESR1 Positive_regulation of HSD17B7 1 0.43 0.41 0.09
113 INT247781 Binding of MERTK and Cmklr1 1 0.07 0 0.09
114 INT211960 Wnt5a Positive_regulation of Car2 1 0.13 0.38 0.08
115 INT192863 Binding of Ddit3 and Esr1 1 0.09 0.67 0.08
116 INT192860 Binding of Calr and Esr1 1 0.06 0.67 0.08
117 INT287879 Binding of WNT5A and FZD5 1 0.06 1.16 0.08
118 INT192865 Binding of Esr1 and Pdia3 1 0.07 0.67 0.08
119 INT192862 Binding of Esr1 and Hspa5 1 0.08 0.68 0.08
120 INT309159 Binding of Cav1 and Positive_regulation of Localization of Esr1 1 0.04 0 0.08
121 INT199973 ESR1 Negative_regulation of EEF1B2P2 1 0.01 0.46 0.08
122 INT302290 Birc5 Regulation of BAK1 1 0.21 1.22 0.07
123 INT204301 Positive_regulation of Hrk Positive_regulation of Positive_regulation of Bak1 1 0.00 1.17 0.07
124 INT38188 PGR Positive_regulation of Gene_expression of ESR1 1 0.42 0.22 0.07
125 INT302131 Negative_regulation of SOD2 Regulation of BAK1 1 0.09 1.22 0.07
126 INT302289 Negative_regulation of Birc5 Regulation of BAK1 1 0.20 1.22 0.07
127 INT285025 Bnip3 Positive_regulation of Bak1 1 0.11 0.78 0.07
128 INT285032 Bnip3 Positive_regulation of Bax 1 0.28 0.77 0.07
129 INT237811 Binding of Esr1 and Stim1 1 0.09 0 0.07
130 INT340401 Positive_regulation of Bax Positive_regulation of Binding of Hrk 1 0.01 0.79 0.07
131 INT302128 SOD2 Regulation of BAK1 1 0.09 1.22 0.07
132 INT339108 Binding of ESR1 and JUP 1 0.38 0.62 0.07
133 INT224293 AR Positive_regulation of Protein_catabolism of ESR1 1 0.24 0.4 0.07
134 INT237809 Esr1 Positive_regulation of Localization of Car2 1 0.09 0.66 0.07
135 INT206855 Binding of ESR1 and PPARA 1 0.03 1.21 0.07
136 INT340395 Binding of Bax and Tg(CAG-EGFP)D4Nagy 1 0.02 0.43 0.07
137 INT272388 Esr1 Regulation of Transcription of Trpv6 1 0.03 0.13 0.06
138 INT302147 PTGER2 Positive_regulation of BAK1 1 0.06 2.08 0.06
139 INT197594 Esr1 Regulation of Esr2 1 0.04 0 0.06
140 INT187845 Binding of ESR1 and Esr2 1 0.01 0.17 0.06
141 INT197592 Esr2 Regulation of Esr1 1 0.04 0 0.06
142 INT142744 Esr1 Regulation of Transcription of Trpv6 1 0.42 0 0.06
143 INT302138 PTGER2 Positive_regulation of Gene_expression of BAK1 1 0.06 2.08 0.06
144 INT197586 Esr2 Regulation of Pgr 1 0.09 0 0.06
145 INT206846 ESR1 Regulation of Gene_expression of PLP1 1 0.06 1.02 0.05
146 INT242974 Mapk8 Negative_regulation of Positive_regulation of Esr1 1 0.01 1.39 0.05
147 INT236591 Binding of Esr1 and Positive_regulation of Tmed4 1 0.04 0.52 0.05
148 INT240726 Binding of Esr1 and Ca2 1 0.02 0.57 0.05
149 INT316248 ESR1 Regulation of Gene_expression of TRPM8 1 0.34 0.17 0.05
150 INT244461 CS Positive_regulation of ESR1 1 0.06 1.15 0.05
151 INT225493 Binding of Esr1 and Pprc1 2 0.01 0.17 0.04
152 INT335702 Esr1 Regulation of Calr 1 0.03 0 0.04
153 INT206848 PLP1 Regulation of Gene_expression of ESR1 1 0.07 0.9 0.04
154 INT206853 ESR1 Positive_regulation of Gene_expression of PCP4 1 0.08 1.39 0.04
155 INT206845 ANXA1 Regulation of Gene_expression of ESR1 1 0.07 0.9 0.04
156 INT201445 ESR1 Regulation of Slc6a3 1 0.02 0.05 0.04
157 INT206851 NR4A1 Regulation of Gene_expression of ESR1 1 0.08 0.9 0.04
158 INT236595 Binding of Esr1 and PELP1 1 0.27 0.17 0.04
159 INT206896 ESR1 Positive_regulation of Gene_expression of Nr1i3 1 0.00 0.36 0.04
160 INT340394 Binding of Bax and Bbc3 1 0.01 0.36 0.04
161 INT206847 ESR1 Negative_regulation of Gene_expression of PTGER3 1 0.08 1.52 0.04
162 INT204298 Bid Positive_regulation of Binding of Bak1 1 0.05 0.57 0.04
163 INT197917 Binding of ESR1 and Sh2b2 1 0.01 0 0.04
164 INT335703 Esr1 Regulation of Localization of Calr 1 0.03 0 0.04
165 INT206849 ESR1 Regulation of Gene_expression of ALDH1A1 1 0.11 2.26 0.04
166 INT206852 ESR1 Regulation of Gene_expression of CRABP2 1 0.08 1.52 0.04
167 INT172902 Binding of Bax and Bcl2 5 0.30 3.19 0.03
168 INT192164 Binding of BAK1 and BCL2 3 0.04 2.8 0.03
169 INT192167 Negative_regulation of Binding of BAK1 and BCL2 2 0.05 1.89 0.03
170 INT183614 Binding of ESR1 and TMED4 2 0.02 0.13 0.03
171 INT192165 Binding of BAK1 and BCL2L1 2 0.06 1.35 0.03
172 INT278579 Esr1 Positive_regulation of Negative_regulation of Tac2 1 0.47 0.25 0.03
173 INT192166 Negative_regulation of Binding of BAK1 and BCL2L1 1 0.05 1.06 0.03
174 INT297737 Cbr1 Positive_regulation of Bax 1 0.06 0.53 0.03
175 INT187388 Esr2 Positive_regulation of Gene_expression of Pgr 1 0.00 0.8 0.03
176 INT224682 Mcl1 Regulation of Bak1 1 0.01 1.09 0.03
177 INT278289 Binding of DBP and ESR1 1 0.03 0.82 0.03
178 INT213902 ESR1 Positive_regulation of EGFR 1 0.48 0.31 0.03
179 INT331960 Positive_regulation of Binding of Esr1 and Tymp 1 0.00 0.15 0.03
180 INT331958 Binding of Esr1 and Tymp 1 0.00 0.15 0.03
181 INT245075 Binding of ESR1 and NR4A1 1 0.01 1.08 0.03
182 INT316773 Esr1 Positive_regulation of Ddit3 1 0.02 0.41 0.03
183 INT333259 Bcl2 Regulation of Bax 1 0.03 0.32 0.03
184 INT224689 Binding of Bak1 and Mcl1 1 0.01 1.09 0.03
185 INT278294 Binding of ESR1 and SHBG 1 0.01 0.82 0.03
186 INT224676 Binding of Bax and Mcl1 1 0.01 1.09 0.03
187 INT221682 Binding of Esr1 and FRTS 1 0.01 0.15 0.03
188 INT213905 ESR1 Positive_regulation of SRC 1 0.14 0.31 0.03
189 INT333249 Cxcl12 Positive_regulation of Positive_regulation of Bak1 1 0.30 0.32 0.03
190 INT215872 Atf4 Regulation of Esr1 1 0.30 0.42 0.03
191 INT224690 Mcl1 Regulation of Bax 1 0.00 1.09 0.03
192 INT333262 Bcl2 Regulation of Bak1 1 0.04 0.31 0.03
193 INT341376 Sod2 Regulation of Bax 1 0.09 0.99 0.03
194 INT283013 Binding of Bak1 and Bcl2 4 0.06 1.03 0
195 INT185852 Binding of BAK1 and BAX 3 0.29 2.5 0
196 INT172906 Binding of Bax and Bcl2l1 2 0.16 2.03 0
197 INT192914 Binding of ESR1 and GOPC 2 0.02 0.61 0
198 INT260342 Binding of Esr1 and Rcc1 1 0.05 0.99 0
199 INT198111 Binding of Esr1 and Esr2 1 0.05 0 0
200 INT335214 Binding of ESR1 and RARS 1 0.08 0.92 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for vagina development. They are ordered first by their pain relevance and then by number of times they were reported in vagina development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34
2 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64
3 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81
4 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69
5 INT37296 Binding of Esr1 117 0.43 62.51 27.33
6 INT20462 Binding of ESR1 210 0.44 102.7 26.34
7 INT100423 Gene_expression of Bax 141 0.75 98.43 24.48
8 INT823 Negative_regulation of ESR1 144 0.58 63.72 22.52
9 INT4067 Negative_regulation of Esr1 97 0.50 43.45 17.52
10 INT17237 Regulation of Esr1 74 0.43 49.09 17.25
11 INT92354 Localization of ESR1 77 0.75 33.04 15.51
12 INT73916 Gene_expression of Esr1 58 0.77 26.59 15.15
13 INT109511 Gene_expression of Bax 133 0.78 113.22 14.36
14 INT2038 Localization of Esr1 104 0.79 40.12 13.27
15 INT79545 Positive_regulation of Gene_expression of ESR1 82 0.64 39.42 12.18
16 INT102110 Positive_regulation of Gene_expression of Bax 42 0.67 35.77 9.51
17 INT102106 Positive_regulation of Bax 48 0.67 30.62 9.28
18 INT80037 Gene_expression of BAK1 58 0.75 39.49 9.08
19 INT15687 Regulation of ESR1 91 0.60 40.42 7.95
20 INT102107 Negative_regulation of Gene_expression of Bax 30 0.57 29.48 7.33
21 INT31333 Gene_expression of Esr2 19 0.69 8.78 6.83
22 INT110987 Transcription of ESR1 45 0.71 24.16 6.72
23 INT98837 Positive_regulation of Bax 72 0.61 63.14 6.41
24 INT22901 Negative_regulation of Gene_expression of Esr1 30 0.42 20.92 6.29
25 INT20280 Positive_regulation of Esr1 32 0.69 18.37 5.69
26 INT43997 Positive_regulation of Gene_expression of Esr1 57 0.51 36.66 5.51
27 INT145929 Regulation of Bax 20 0.60 18.12 5.35
28 INT109513 Positive_regulation of Gene_expression of Bax 37 0.67 29.52 5.06
29 INT16621 Negative_regulation of Esr1 20 0.54 8.2 4.84
30 INT133630 Negative_regulation of Gene_expression of ESR1 42 0.52 23.89 4.57
31 INT99504 Negative_regulation of Bax 19 0.56 8.89 4.44
32 INT103345 Positive_regulation of Gene_expression of BAK1 10 0.57 6.4 4.19
33 INT117205 Transcription of Esr1 23 0.65 9.4 4.14
34 INT123752 Regulation of Bax 19 0.60 16.45 4
35 INT112692 Localization of Bax 31 0.80 20.97 3.98
36 INT77385 Gene_expression of Esr2 18 0.75 4.69 3.92
37 INT15375 Gene_expression of AXL 21 0.65 18.5 3.74
38 INT218955 Protein_catabolism of ESR1 9 0.92 3.95 3.74
39 INT20461 Binding of Esr1 34 0.48 9.58 3.66
40 INT178631 Phosphorylation of ESR1 21 0.75 9.16 3.36
41 INT73918 Transcription of Esr1 21 0.66 8.74 3.12
42 INT31541 Regulation of Esr1 15 0.54 4.12 2.82
43 INT74293 Positive_regulation of BAK1 13 0.60 14.13 2.73
44 INT174727 Positive_regulation of Positive_regulation of ESR1 14 0.44 6.3 2.7
45 INT205081 Positive_regulation of Gene_expression of AXL 10 0.58 11.27 2.37
46 INT108796 Binding of ESR2 5 0.46 6.84 2.36
47 INT102146 Phosphorylation of Bax 4 0.66 3.48 2.35
48 INT102234 Gene_expression of ESR2 17 0.65 9.29 2.3
49 INT154970 Localization of Bax 15 0.74 11.12 2.11
50 INT98836 Transcription of Bax 6 0.69 5.04 1.96
51 INT109800 Binding of Esr2 8 0.42 1.79 1.93
52 INT73913 Regulation of Gene_expression of Esr1 2 0.41 2.24 1.92
53 INT134442 Transcription of Bax 14 0.67 7.6 1.9
54 INT218959 Negative_regulation of Protein_catabolism of ESR1 3 0.37 0.97 1.9
55 INT135540 Negative_regulation of Bax 16 0.48 11.8 1.89
56 INT134443 Binding of Bax 10 0.47 5.62 1.84
57 INT104883 Positive_regulation of Positive_regulation of Bax 4 0.45 4.05 1.74
58 INT153918 Binding of Esr2 3 0.33 2.56 1.7
59 INT96971 Positive_regulation of Gene_expression of Esr1 6 0.46 2.27 1.67
60 INT30076 Negative_regulation of Esr2 1 0.01 0 1.63
61 INT43637 Positive_regulation of AXL 11 0.58 11.71 1.59
62 INT222089 Positive_regulation of Localization of Esr1 19 0.49 8.73 1.58
63 INT103967 Negative_regulation of Gene_expression of BAK1 8 0.42 7.02 1.54
64 INT62800 Regulation of BAK1 7 0.41 10.12 1.47
65 INT146785 Positive_regulation of Localization of Bax 7 0.69 6.16 1.47
66 INT109512 Negative_regulation of Gene_expression of Bax 12 0.42 8.04 1.44
67 INT218313 Localization of RBP4 5 0.79 15.68 1.4
68 INT112695 Negative_regulation of Protein_catabolism of Bax 3 0.36 1.72 1.3
69 INT142017 Positive_regulation of Positive_regulation of BAK1 2 0.52 1.74 1.3
70 INT154969 Positive_regulation of Localization of Bax 4 0.64 3.42 1.27
71 INT8511 Localization of Esr1 6 0.80 3.27 1.26
72 INT128752 Negative_regulation of Localization of Esr1 11 0.43 4.8 1.23
73 INT112693 Protein_catabolism of Bax 5 0.74 3.17 1.2
74 INT824 Negative_regulation of Negative_regulation of ESR1 3 0.42 1.53 1.18
75 INT150074 Gene_expression of WNT5A 8 0.75 6.3 1.17
76 INT141189 Negative_regulation of Transcription of Bax 1 0.41 1.42 1.14
77 INT81945 Negative_regulation of Binding of Esr1 3 0.32 0.55 1.06
78 INT93094 Gene_expression of Bak1 13 0.52 13.94 1.02
79 INT66862 Regulation of Esr2 3 0.24 1.56 1.01
80 INT71906 Regulation of Gene_expression of ESR1 22 0.41 11.01 0.98
81 INT154468 Negative_regulation of Transcription of ESR1 3 0.29 1.14 0.96
82 INT175507 Regulation of Gene_expression of Bax 13 0.50 10.91 0.95
83 INT173747 Regulation of Positive_regulation of Esr1 4 0.37 4.85 0.95
84 INT236576 Positive_regulation of Binding of Esr1 3 0.41 2.39 0.92
85 INT154465 Negative_regulation of Transcription of Esr1 1 0.05 0 0.92
86 INT128755 Protein_catabolism of Esr1 10 0.57 4.61 0.9
87 INT135542 Positive_regulation of Bak1 17 0.43 16.12 0.88
88 INT218315 Gene_expression of RBP4 25 0.76 18.19 0.85
89 INT73914 Negative_regulation of Transcription of Esr1 3 0.39 0.75 0.84
90 INT174728 Positive_regulation of Transcription of ESR1 10 0.47 3.3 0.83
91 INT125092 Negative_regulation of Binding of ESR1 8 0.42 4.15 0.82
92 INT33818 Positive_regulation of Negative_regulation of Esr1 3 0.40 0.98 0.82
93 INT144697 Regulation of Gene_expression of Bax 8 0.37 9.5 0.81
94 INT158075 Positive_regulation of Esr2 1 0.28 0.5 0.77
95 INT161778 Regulation of Gene_expression of Esr1 13 0.51 9.46 0.73
96 INT92082 Regulation of Binding of ESR1 5 0.45 2.41 0.73
97 INT239494 Regulation of Localization of Esr1 4 0.19 1.15 0.72
98 INT14040 Binding of Bak1 2 0.30 0.55 0.72
99 INT73917 Regulation of Transcription of Esr1 4 0.25 1.5 0.7
100 INT14041 Regulation of Binding of Bak1 1 0.23 0 0.68
101 INT204290 Positive_regulation of Bak1 3 0.22 5.19 0.66
102 INT191177 Regulation of Localization of ESR1 7 0.42 2.04 0.64
103 INT9836 Negative_regulation of Negative_regulation of Esr1 3 0.29 0.95 0.63
104 INT150075 Positive_regulation of Gene_expression of WNT5A 2 0.67 2.53 0.59
105 INT238828 Regulation of RBP4 6 0.60 2.7 0.58
106 INT285007 Regulation of Bak1 1 0.20 3.46 0.56
107 INT173748 Phosphorylation of Esr1 11 0.77 5.7 0.55
108 INT176242 Binding of Bax 10 0.42 10.18 0.52
109 INT173744 Positive_regulation of Positive_regulation of Esr1 10 0.43 7.05 0.52
110 INT135541 Negative_regulation of Bak1 6 0.30 4.52 0.49
111 INT190899 Negative_regulation of Phosphorylation of ESR1 3 0.33 1.01 0.49
112 INT30075 Localization of Esr2 2 0.01 0.78 0.49
113 INT102108 Protein_catabolism of Bax 8 0.64 5.69 0.48
114 INT134446 Positive_regulation of Binding of Bax 1 0.49 0.72 0.48
115 INT240710 Positive_regulation of Regulation of Esr1 1 0.09 1.34 0.47
116 INT152059 Regulation of Transcription of Bax 1 0.26 0.07 0.42
117 INT174725 Positive_regulation of Localization of ESR1 8 0.47 2.45 0.41
118 INT109801 Transcription of Esr2 2 0.69 2.08 0.41
119 INT150946 Negative_regulation of Positive_regulation of Bak1 2 0.29 3.02 0.4
120 INT135802 Positive_regulation of Negative_regulation of Bax 2 0.41 0.57 0.4
121 INT348631 Regulation of Esr2 1 0.40 0.87 0.4
122 INT268930 Regulation of Regulation of Esr1 2 0.41 0.48 0.38
123 INT186535 Negative_regulation of Gene_expression of Esr2 2 0.25 1.07 0.38
124 INT178630 Positive_regulation of Negative_regulation of ESR1 2 0.04 0.64 0.35
125 INT194086 Negative_regulation of Gene_expression of ESR2 1 0.03 1.22 0.35
126 INT204069 Negative_regulation of Positive_regulation of Bax 5 0.31 3.08 0.34
127 INT236580 Regulation of Binding of Esr1 4 0.39 1.1 0.34
128 INT169538 Negative_regulation of Localization of Bax 3 0.49 1.41 0.34
129 INT176586 Positive_regulation of Binding of ESR1 11 0.41 4.64 0.33
130 INT218314 Binding of RBP4 9 0.36 6.27 0.33
131 INT184482 Positive_regulation of Positive_regulation of Bax 5 0.41 4.7 0.33
132 INT172216 Binding of Bak1 5 0.25 8.48 0.33
133 INT221191 Negative_regulation of Localization of Bax 4 0.38 2.85 0.33
134 INT93093 Regulation of Gene_expression of Bak1 3 0.30 2.09 0.32
135 INT183916 Negative_regulation of Binding of Esr1 1 0.06 0.91 0.32
136 INT122950 Binding of BAK1 16 0.41 12.85 0.31
137 INT140379 Positive_regulation of Gene_expression of Bak1 4 0.27 2.27 0.31
138 INT192845 Negative_regulation of Positive_regulation of Esr1 2 0.35 1.15 0.31
139 INT66863 Regulation of Gene_expression of Esr2 1 0.03 0 0.31
140 INT73915 Negative_regulation of Negative_regulation of Esr1 1 0.40 0.06 0.31
141 INT218316 Positive_regulation of RBP4 2 0.68 7.54 0.3
142 INT229853 Gene_expression of Bak1 2 0.25 2.04 0.29
143 INT185428 Gene_expression of Lhx1 4 0.75 2.6 0.28
144 INT153772 Negative_regulation of Localization of ESR1 7 0.54 4.42 0.27
145 INT209222 Gene_expression of Tyro3 3 0.22 0.47 0.27
146 INT102111 Positive_regulation of Protein_catabolism of Bax 2 0.45 1.14 0.27
147 INT102801 Regulation of ESR2 1 0.51 0 0.27
148 INT102800 Regulation of Gene_expression of ESR2 1 0.22 0 0.27
149 INT150947 Positive_regulation of Positive_regulation of Bak1 1 0.05 0.6 0.25
150 INT138751 Localization of ESR2 2 0.72 1.51 0.24
151 INT135543 Negative_regulation of Positive_regulation of Bax 5 0.30 6.4 0.23
152 INT96972 Positive_regulation of Binding of Esr1 4 0.22 1.35 0.21
153 INT187555 Transcription of BAK1 3 0.19 2.6 0.21
154 INT187556 Regulation of Transcription of BAK1 1 0.02 1.22 0.21
155 INT213914 Positive_regulation of NCOA3 1 0.44 1.34 0.2
156 INT282088 Localization of Bak1 6 0.54 3.78 0.19
157 INT186021 Positive_regulation of Positive_regulation of Esr1 1 0.08 0 0.19
158 INT161606 Positive_regulation of MERTK 1 0.67 0.9 0.18
159 INT300463 Regulation of Regulation of Bax 1 0.29 1.33 0.18
160 INT42242 Binding of MERTK 1 0.36 0.77 0.18
161 INT176571 Negative_regulation of Positive_regulation of ESR1 5 0.47 3.15 0.17
162 INT198036 Negative_regulation of BAK1 5 0.27 5.98 0.17
163 INT185427 Negative_regulation of Lhx1 4 0.42 3.48 0.17
164 INT233570 Gene_expression of Rbp4 4 0.66 3.4 0.17
165 INT291955 Positive_regulation of Protein_catabolism of Esr1 1 0.06 0.14 0.17
166 INT269777 Regulation of Regulation of Esr1 2 0.02 1.17 0.16
167 INT340373 Negative_regulation of Rbp4 1 0.17 1.96 0.16
168 INT176461 Protein_catabolism of Esr1 1 0.12 0.37 0.16
169 INT213912 Positive_regulation of Gene_expression of NCOA3 1 0.44 1.06 0.15
170 INT238831 Regulation of Localization of RBP4 1 0.27 1.71 0.15
171 INT183400 Positive_regulation of Transcription of Esr1 4 0.30 1.06 0.14
172 INT320315 Protein_catabolism of BAK1 3 0.76 3.13 0.13
173 INT70018 Localization of AXL 2 0.55 0.49 0.13
174 INT285005 Negative_regulation of Bak1 1 0.14 0.16 0.13
175 INT185872 Localization of BAK1 6 0.74 11.28 0.12
176 INT162109 Negative_regulation of Gene_expression of Esr1 4 0.16 2.41 0.12
177 INT265485 Positive_regulation of Localization of BAK1 4 0.50 5.17 0.12
178 INT286293 Binding of Rbp4 3 0.17 0.61 0.12
179 INT185907 Positive_regulation of Binding of BAK1 2 0.60 1.59 0.12
180 INT238490 Regulation of Regulation of BAK1 1 0.19 2.56 0.12
181 INT347724 Gene_expression of MERTK 1 0.58 0.65 0.12
182 INT232556 Positive_regulation of Phosphorylation of Esr1 1 0.20 0.41 0.12
183 INT336888 Negative_regulation of Transcription of Bax 1 0.07 0.68 0.11
184 INT162574 Gene_expression of Wnt5a 7 0.47 0.92 0.1
185 INT213913 Gene_expression of NCOA3 3 0.50 1.11 0.1
186 INT282594 Localization of WNT5A 2 0.18 0.89 0.1
187 INT233483 Regulation of Gene_expression of Wnt5a 1 0.19 0.33 0.1
188 INT213911 Positive_regulation of Positive_regulation of NCOA3 1 0.32 0.67 0.1
189 INT304137 Regulation of Localization of Bax 2 0.24 1.7 0.09
190 INT261361 Negative_regulation of Esr2 1 0.15 0.67 0.09
191 INT162576 Positive_regulation of Wnt5a 3 0.48 0.71 0.08
192 INT224299 Positive_regulation of Protein_catabolism of ESR1 3 0.64 1.43 0.07
193 INT327140 Regulation of Localization of BAK1 1 0.45 0.71 0.07
194 INT285012 Positive_regulation of Positive_regulation of Bak1 1 0.16 0.77 0.07
195 INT290078 Regulation of WNT5A 1 0.07 2.3 0.07
196 INT322649 Positive_regulation of Localization of Bak1 1 0.47 1.04 0.07
197 INT307466 Positive_regulation of Phosphorylation of Bax 1 0.15 0.76 0.07
198 INT285008 Negative_regulation of Regulation of Bak1 1 0.14 0.87 0.07
199 INT178868 Regulation of Positive_regulation of ESR1 1 0.42 0.52 0.07
200 INT253882 Positive_regulation of Localization of Esr1 1 0.30 1.21 0.06
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