GO:0060074

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Name synapse maturation
Categary Process
Go Slim No
Go Link GO:0060074
Unique Molecular Interactions 25
Total Molecular Interactions 41
Total Single Events 107
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for synapse maturation. They are ordered first by their pain relevance and then by number of times they were reported for synapse maturation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT309708 Palm Regulation of Positive_regulation of Penk 1 0.19 1.25 0.91
2 INT303179 Binding of Dlgap1 and Shank1 1 0.22 0.31 0.1
3 INT341008 Nrg1 Regulation of Binding of Erbb4 1 0.04 0 0.09
4 INT303180 Trim3 Negative_regulation of Shank1 1 0.40 0 0.09
5 INT303176 Gene_expression of Trim3 Positive_regulation of Protein_catabolism of Shank1 1 0.44 0 0.07
6 INT251776 Negative_regulation of TXK Negative_regulation of ERBB4 1 0.04 1.07 0.06
7 INT354963 Binding of Cttn and Shank1 1 0.12 0 0.04
8 INT354971 Binding of HOMER1 and Shank1 1 0.01 0 0.04
9 INT303170 Gene_expression of Trim3 Negative_regulation of Shank1 1 0.40 0.12 0.04
10 INT231276 Erbb4 Positive_regulation of Nrg1 2 0.35 0.06 0.03
11 INT316057 Binding of Erbb4 and Nrg1 2 0.03 0.38 0.03
12 INT316060 Binding of Erbb4 and Ncor2 1 0.12 0.41 0.03
13 INT316061 Positive_regulation of Binding of Erbb4 and Nrg1 1 0.03 0.38 0.03
14 INT231275 Erbb4 Positive_regulation of Gene_expression of Nrg1 1 0.35 0 0.03
15 INT272594 Binding of Dlg4 and Shank1 1 0.20 0 0.03
16 INT316055 Binding of Erbb4 and Tab2 1 0.23 0.4 0.03
17 INT294088 Binding of ERBB2 and ERBB4 2 0.13 0.88 0
18 INT294089 Negative_regulation of Binding of ERBB2 and ERBB4 1 0.08 0.6 0
19 INT303159 Trim3 Negative_regulation of Gene_expression of Shank1 1 0.40 0 0
20 INT80013 BTC Positive_regulation of ERBB4 1 0.31 0.26 0
21 INT303185 Binding of Shank1 and Trim3 1 0.35 0 0
22 INT303161 Gene_expression of Trim3 Positive_regulation of Shank1 1 0.44 0 0
23 INT303169 Trim3 Regulation of Gene_expression of Shank1 1 0.42 0 0
24 INT303163 Shank1 Positive_regulation of Trim3 1 0.47 0 0
25 INT303173 Negative_regulation of Trim3 Negative_regulation of Shank1 1 0.40 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for synapse maturation. They are ordered first by their pain relevance and then by number of times they were reported in synapse maturation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT237409 Localization of Erbb4 3 0.57 1.31 1.41
2 INT128413 Positive_regulation of Shank1 2 0.70 0.61 1.16
3 INT128411 Regulation of Shank1 2 0.45 0.81 0.95
4 INT237411 Negative_regulation of Localization of Erbb4 1 0.25 0.08 0.64
5 INT327693 Regulation of Palm 1 0.18 0 0.54
6 INT309707 Positive_regulation of Palm 1 0.39 0.28 0.46
7 INT283838 Gene_expression of Erbb4 5 0.59 2.37 0.42
8 INT303211 Gene_expression of Shank1 1 0.64 0.48 0.4
9 INT80017 Gene_expression of ERBB4 10 0.77 6.94 0.26
10 INT303216 Protein_catabolism of Shank1 1 0.83 0 0.15
11 INT303217 Binding of Shank1 1 0.36 0 0.11
12 INT303233 Negative_regulation of Gene_expression of Shank1 1 0.49 0.07 0.1
13 INT80018 Binding of ERBB4 5 0.35 2.84 0.09
14 INT80019 Regulation of ERBB4 2 0.27 1.52 0.09
15 INT231258 Binding of Erbb4 3 0.23 0.16 0.08
16 INT303212 Positive_regulation of Protein_catabolism of Shank1 1 0.42 0 0.08
17 INT251797 Positive_regulation of ERBB4 3 0.33 3.14 0.06
18 INT272574 Gene_expression of Shank1 2 0.61 0.22 0.06
19 INT303195 Positive_regulation of Gene_expression of Shank1 1 0.42 0.08 0.06
20 INT80014 Negative_regulation of Gene_expression of ERBB4 1 0.42 0.47 0.05
21 INT80016 Negative_regulation of Transcription of ERBB4 1 0.43 0.47 0.05
22 INT80015 Transcription of ERBB4 1 0.53 0.76 0.05
23 INT303204 Negative_regulation of Shank1 1 0.42 0.11 0.04
24 INT316038 Positive_regulation of Erbb4 2 0.45 0.22 0.03
25 INT283837 Phosphorylation of Erbb4 1 0.63 0.95 0.03
26 INT307588 Positive_regulation of Gene_expression of ERBB4 2 0.38 1.84 0
27 INT303227 Regulation of Negative_regulation of Shank1 1 0.26 0 0
28 INT340959 Negative_regulation of Erbb4 1 0.06 0 0
29 INT335225 Negative_regulation of ERBB4 1 0.11 0.94 0
30 INT303202 Negative_regulation of Protein_catabolism of Shank1 1 0.49 0 0
31 INT303209 Positive_regulation of Positive_regulation of Shank1 1 0.34 0 0
32 INT303193 Localization of Shank1 1 0.62 0.19 0
33 INT303199 Regulation of Gene_expression of Shank1 1 0.23 0 0
34 INT354939 Positive_regulation of Gene_expression of Shank1 1 0.45 0.14 0
35 INT340943 Negative_regulation of Gene_expression of Erbb4 1 0.06 0 0
36 INT340970 Positive_regulation of Gene_expression of Erbb4 1 0.08 0 0
37 INT303232 Regulation of Protein_catabolism of Shank1 1 0.38 0 0
38 INT286984 Phosphorylation of ERBB4 1 0.41 2.87 0
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