GO:0060137

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Name maternal process involved in parturition
Categary Process
Go Slim No
Go Link GO:0060137
Unique Molecular Interactions 359
Total Molecular Interactions 521
Total Single Events 4427
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for maternal process involved in parturition. They are ordered first by their pain relevance and then by number of times they were reported for maternal process involved in parturition. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT149492 PNOC Negative_regulation of Gene_expression of CCL2 1 0.15 0.68 3.17
2 INT124121 IL6 Positive_regulation of CCL2 1 0.26 1.84 2.25
3 INT124120 IL6 Regulation of CCL2 1 0.15 1.8 2.22
4 INT128997 Cxcl1 Positive_regulation of Localization of Ccl2 1 0.72 1.54 2.16
5 INT128996 Ccl2 Positive_regulation of Localization of Calca 1 0.68 1.43 2
6 INT91607 Binding of EDN1 and POMC 1 0.12 0 1.9
7 INT136034 Edn1 Regulation of Trpv1 2 0.66 0.39 1.58
8 INT31772 Ednra Positive_regulation of Nppa 1 0.05 0.13 1.33
9 INT95275 Binding of Edn1 and Ece1 1 0.32 2.09 1.3
10 INT95274 Regulation of Binding of Edn1 and Ece1 1 0.39 2.09 1.3
11 INT62596 Binding of Edn1 and Nppa 1 0.27 1.77 1.22
12 INT200455 OPRK1 Positive_regulation of Gene_expression of CCL2 1 0.19 0.07 1.21
13 INT172500 Ednra Positive_regulation of Coc 1 0.01 1 1.2
14 INT201067 Binding of Edn1 and Ednra 2 0.18 1.36 1.18
15 INT260810 Binding of CXCL10 and CCL2 1 0.10 1.37 1.12
16 INT29874 OXTR Negative_regulation of POMC 1 0.22 0 1.1
17 INT10238 Binding of EDN1 and Calca 1 0.00 1.07 1.06
18 INT167173 Binding of Ccl2 and Ccr2 2 0.30 1.15 0.98
19 INT54972 Binding of EDNRA and EDNRB 7 0.52 3.31 0.97
20 INT135585 CSF2 Regulation of CCL2 1 0.13 2.51 0.95
21 INT136033 Edn1 Positive_regulation of Trpv1 1 0.50 0.34 0.95
22 INT77859 EDN1 Positive_regulation of MC1R 2 0.64 0.34 0.94
23 INT123023 Ednra Regulation of Adarb1 1 0.00 0 0.93
24 INT129003 Ccl2 Positive_regulation of ANTXRL 1 0.00 0.68 0.92
25 INT123024 Csf2 Regulation of Ednra 1 0.06 0 0.92
26 INT128701 Ednra Regulation of EDNRB 1 0.17 0.58 0.84
27 INT146919 Tnf Positive_regulation of Gene_expression of Ccl2 1 0.16 1.44 0.84
28 INT128702 Ednra Regulation of EDNRA 1 0.00 0.58 0.84
29 INT287494 CRP Positive_regulation of Gene_expression of CCL2 2 0.30 2.33 0.83
30 INT149561 Tgfb1 Positive_regulation of Gene_expression of CCL2 1 0.00 0 0.83
31 INT149563 Tgfb1 Positive_regulation of CCL2 1 0.00 0 0.83
32 INT106859 EDN1 Positive_regulation of Transcription of MC1R 1 0.22 0 0.82
33 INT87489 CALCA Positive_regulation of Gene_expression of CCL2 1 0.43 0.14 0.81
34 INT219911 Edn1 Regulation of Gene_expression of Trpv1 1 0.23 0.57 0.8
35 INT239671 Binding of Ccl2 and Gtf3a 1 0.02 1.34 0.79
36 INT149495 PNOC Negative_regulation of CCL2 1 0.11 0.16 0.77
37 INT258644 Binding of CCL2 and CCL5 1 0.36 1.6 0.74
38 INT258643 Positive_regulation of Binding of CCL2 and CCL5 1 0.49 1.61 0.74
39 INT123229 OXTR Regulation of Localization of PRL 2 0.30 0 0.73
40 INT64117 Binding of Edn1 and Ins1 1 0.06 0.85 0.71
41 INT222493 Edn1 Positive_regulation of Localization of Prl 1 0.10 0 0.71
42 INT29875 OXTR Negative_regulation of Positive_regulation of POMC 1 0.31 0 0.7
43 INT120017 CCL2 Positive_regulation of CCL3 1 0.01 0.99 0.7
44 INT120020 VEGFA Positive_regulation of CCL2 1 0.00 1 0.7
45 INT120035 CCL2 Positive_regulation of Prap1 1 0.00 0.99 0.7
46 INT63557 Binding of Edn1 and Edn3 1 0.23 0.63 0.7
47 INT130717 Binding of OPRM1 and Positive_regulation of Localization of CCL2 1 0.00 0.72 0.68
48 INT278827 Binding of EDN1 and EDNRB 3 0.17 2.7 0.67
49 INT134286 PLD2 Regulation of Regulation of EDNRA 1 0.10 0 0.67
50 INT116441 IL1B Positive_regulation of Gene_expression of CCL2 2 0.04 0.62 0.65
51 INT313702 Binding of Edn1 and Fig4 1 0.16 0 0.65
52 INT153750 Binding of CCL2 and Crp 1 0.02 1.8 0.65
53 INT313698 Binding of Calca and Edn1 1 0.30 0 0.65
54 INT153751 Regulation of Binding of CCL2 and Crp 1 0.03 1.8 0.65
55 INT281130 Ccl2 Regulation of Gene_expression of Ccr2 1 0.04 1.09 0.64
56 INT264329 Binding of IL-17 and Positive_regulation of Localization of Ccl2 1 0.13 1.65 0.64
57 INT281134 Ccl2 Positive_regulation of Gene_expression of Ccr2 1 0.08 1.09 0.64
58 INT281122 Ccl2 Regulation of Ccr2 1 0.04 1.09 0.63
59 INT219921 EDNRA Negative_regulation of Trpv1 1 0.13 0.36 0.63
60 INT182266 EDN1 Positive_regulation of Gene_expression of MMP13 1 0.35 2.03 0.63
61 INT174860 VEGFA Positive_regulation of Localization of CCL2 1 0.21 1.68 0.63
62 INT219919 EDNRA Negative_regulation of Edn1 1 0.15 0.36 0.63
63 INT178097 Binding of EDN1 and EDNRA 7 0.21 5.97 0.62
64 INT252772 ELANE Regulation of Gene_expression of CCL2 1 0.05 2.16 0.62
65 INT252826 ROS1 Regulation of Gene_expression of CCL2 1 0.20 2.17 0.62
66 INT230734 Negative_regulation of Binding of EDNRA and Pah 1 0.02 3.26 0.61
67 INT230735 Binding of EDNRA and Pah 1 0.02 3.22 0.6
68 INT178087 EDN1 Positive_regulation of MMP13 2 0.23 1.58 0.59
69 INT176470 TNF Positive_regulation of Gene_expression of CCL2 1 0.15 0.62 0.58
70 INT130162 Pomc Positive_regulation of Gene_expression of Edn1 1 0.25 0 0.58
71 INT147201 Binding of CCL2 and Hsp70-2os 1 0.00 0.76 0.57
72 INT147575 Binding of Ahr and Cyp1a1 2 0.15 0.15 0.54
73 INT62597 Binding of Edn1 and Vip 1 0.23 0.79 0.54
74 INT147579 Binding of ATF4 and Cyp1a1 1 0.01 0.15 0.54
75 INT278824 Positive_regulation of Binding of EDNRA and EDNRB 1 0.12 1.65 0.53
76 INT110474 YY1 Positive_regulation of Positive_regulation of EDN1 1 0.56 0.15 0.53
77 INT130160 Pomc Regulation of Edn1 1 0.25 0 0.53
78 INT132438 Binding of AGT and OXTR 1 0.08 1.03 0.53
79 INT162500 AHR Regulation of CYP1A1 3 0.19 0.18 0.51
80 INT278825 Positive_regulation of Binding of EDN1 and EDNRB 3 0.16 1.24 0.49
81 INT94015 Binding of EDN1 and INSRR 1 0.04 0 0.49
82 INT94024 Binding of EDN1 and EDN3 1 0.27 0 0.49
83 INT295708 Binding of EGF and CCL2 1 0.01 0.79 0.49
84 INT99571 Edn1 Positive_regulation of Localization of Ednra 1 0.01 0.32 0.47
85 INT217040 Negative_regulation of IRF6 Positive_regulation of CCL2 1 0.00 1.24 0.47
86 INT217039 IRF6 Positive_regulation of CCL2 1 0.00 1.24 0.47
87 INT110476 EDN1 Positive_regulation of Localization of PRKCZ 1 0.25 0.07 0.46
88 INT110475 EDN1 Regulation of PRKCA 1 0.05 0.07 0.45
89 INT219910 EDN1 Positive_regulation of Positive_regulation of EDNRA 1 0.00 0.3 0.45
90 INT94093 Pnoc Positive_regulation of EDNRA 1 0.03 0.1 0.44
91 INT112800 CASP1 Positive_regulation of Gene_expression of CCL2 1 0.04 0.48 0.43
92 INT184543 Agt Positive_regulation of Ccl2 1 0.16 3.18 0.43
93 INT345288 AGT Positive_regulation of Localization of CCL2 1 0.01 1.5 0.43
94 INT345291 AGT Positive_regulation of CCL2 1 0.01 1.39 0.43
95 INT313704 Smn1 Negative_regulation of Gene_expression of Edn1 1 0.32 0 0.42
96 INT230724 EDN1 Positive_regulation of EDNRA 3 0.24 4.12 0.39
97 INT77683 Ednra Negative_regulation of LH 1 0.03 0.23 0.39
98 INT185530 Binding of AGT and EDNRA 1 0.00 0.31 0.38
99 INT116678 Binding of ARRB1 and Oxtr 1 0.13 0.15 0.38
100 INT173704 Binding of PCOS1 and Edn1 1 0.01 0.99 0.37
101 INT313701 Calca Negative_regulation of Binding of Edn1 1 0.30 0.14 0.37
102 INT163909 CCL2 Positive_regulation of Positive_regulation of Ccr2 1 0.05 0.19 0.36
103 INT80444 Binding of EDNRA and SPR 1 0.05 0.1 0.36
104 INT42560 OXTR Positive_regulation of Gene_expression of PGF 1 0.50 0.36 0.36
105 INT201068 Binding of Edn1 and Ednrb 2 0.18 1.23 0.35
106 INT163906 CCL2 Positive_regulation of CCR2 1 0.18 0.2 0.35
107 INT163908 CCL2 Positive_regulation of Ccr2 1 0.05 0.2 0.35
108 INT161796 Binding of ECE1 and EDN1 2 0.21 2.23 0.34
109 INT207576 RETN Positive_regulation of Gene_expression of EDN1 1 0.05 0.78 0.33
110 INT134888 Negative_regulation of TNFRSF11A Negative_regulation of Gene_expression of CCL2 1 0.24 0.38 0.33
111 INT143567 Edn1 Regulation of Ptgs2 1 0.26 0.17 0.33
112 INT303030 Binding of Ednra and MCPH1 1 0.00 1.02 0.32
113 INT99842 Edn1 Negative_regulation of Localization of Ren 1 0.24 0.43 0.32
114 INT119603 H2-Ab1 Regulation of EDNRA 1 0.00 0.07 0.32
115 INT119602 EDNRA Regulation of H2-Ab1 1 0.00 0.07 0.32
116 INT303005 Binding of Ednra and Pah 1 0.06 1.02 0.32
117 INT67266 Edn1 Negative_regulation of Ece1 1 0.19 0.17 0.32
118 INT104932 AHR Positive_regulation of CYP1A1 1 0.43 0.83 0.31
119 INT182262 EDN1 Positive_regulation of Gene_expression of NOS2 1 0.28 0.79 0.31
120 INT69365 Binding of EDNRA and Pnoc 1 0.00 0 0.31
121 INT71519 Edn1 Positive_regulation of Gene_expression of Adarb1 1 0.02 0.48 0.31
122 INT313740 Negative_regulation of NOS1 Positive_regulation of Gene_expression of Ccl2 1 0.02 0.38 0.3
123 INT284137 EDNRB Regulation of EDNRA 1 0.07 0.09 0.3
124 INT116680 Binding of ADRBK1 and Oxtr 1 0.18 0.14 0.3
125 INT117588 Binding of C5AR1 and EDNRA 1 0.40 0.38 0.3
126 INT171257 TNFSF12 Positive_regulation of CCL2 1 0.01 0.3 0.29
127 INT191505 NLRP3 Positive_regulation of Protein_catabolism of EDN1 1 0.00 1.1 0.28
128 INT178102 EDNRA Positive_regulation of Localization of TIMP1 1 0.06 0.97 0.28
129 INT335134 PPARA Negative_regulation of Cyp1a1 1 0.47 0 0.28
130 INT178088 EDNRA Positive_regulation of Transcription of TIMP1 1 0.06 0.97 0.28
131 INT306107 Binding of CCL2 and Ccr2 1 0.06 0 0.28
132 INT294709 IRF6 Positive_regulation of Gene_expression of CCL2 1 0.08 0.14 0.28
133 INT252806 F2 Positive_regulation of Gene_expression of CCL2 1 0.01 0.8 0.27
134 INT306941 Tnfsf12 Positive_regulation of Gene_expression of CCL2 1 0.03 1.65 0.27
135 INT132363 Lgals1 Positive_regulation of Gene_expression of Ccl2 1 0.26 0.14 0.27
136 INT342458 CSF1 Positive_regulation of Gene_expression of CCL2 1 0.17 0.84 0.27
137 INT353448 BRCA1 Positive_regulation of CCL2 1 0.01 1.37 0.26
138 INT120896 Binding of CCL2 and Il6 1 0.08 1.2 0.26
139 INT124117 Apcs Negative_regulation of Ednra 1 0.09 0 0.26
140 INT312768 Pon1 Negative_regulation of Gene_expression of Ccl2 1 0.06 1.42 0.26
141 INT219918 Positive_regulation of EDNRA Positive_regulation of Trpv1 1 0.13 0 0.26
142 INT162502 NEUROD1 Regulation of CYP1A1 2 0.07 0.09 0.25
143 INT115413 Binding of Penk and Oxtr 1 0.00 0 0.25
144 INT252822 CCL2 Positive_regulation of Positive_regulation of FOS 1 0.04 0.75 0.25
145 INT342456 AGT Positive_regulation of Gene_expression of CCL2 1 0.07 0.63 0.25
146 INT252786 CCL2 Regulation of Positive_regulation of FOS 1 0.05 0.75 0.25
147 INT256227 Binding of EDN1 and VEGFA 1 0.18 2.92 0.25
148 INT178095 EDN1 Positive_regulation of MMP3 1 0.04 0.88 0.24
149 INT178076 EDN1 Positive_regulation of MMP2 1 0.04 0.88 0.24
150 INT178085 EDN1 Positive_regulation of MMP7 1 0.06 0.89 0.24
151 INT178141 EDN1 Positive_regulation of Timp1 1 0.30 0.89 0.24
152 INT36875 Binding of EDNRA and SYNCRIP 1 0.01 0 0.24
153 INT178075 EDN1 Positive_regulation of PLAU 1 0.06 0.95 0.24
154 INT178104 EDN1 Positive_regulation of Localization of TIMP1 1 0.05 0.83 0.24
155 INT178094 Positive_regulation of EDN1 Positive_regulation of PLAU 1 0.06 0.95 0.24
156 INT178142 EDN1 Positive_regulation of Localization of Timp1 1 0.28 0.89 0.24
157 INT178077 EDN1 Positive_regulation of MMP9 1 0.06 0.88 0.24
158 INT281133 Binding of Ccl2 and Cxcr4 1 0.06 0.63 0.24
159 INT6641 Negative_regulation of Binding of Avpr2 and Oxtr 1 0.04 0.06 0.23
160 INT6642 Binding of Avpr2 and Oxtr 1 0.03 0.06 0.23
161 INT6644 Binding of Avpr1a and Oxtr 1 0.14 0.05 0.23
162 INT252777 ROS1 Positive_regulation of Gene_expression of CCL2 1 0.31 0.77 0.23
163 INT57171 Binding of RYBP and Cyp1a1 1 0.01 0 0.23
164 INT6643 Negative_regulation of Binding of Avpr1a and Oxtr 1 0.16 0.05 0.23
165 INT112796 IL4I1 Positive_regulation of Gene_expression of CCL2 1 0.07 0 0.23
166 INT112801 IL4I1 Positive_regulation of CCL2 1 0.03 0 0.23
167 INT182272 EDN1 Regulation of Gene_expression of MMP13 1 0.26 0.87 0.22
168 INT120376 Bad Positive_regulation of Gene_expression of Oxtr 1 0.08 0 0.22
169 INT91686 Mb Positive_regulation of Edn1 1 0.03 0.29 0.22
170 INT284139 EDNRB Positive_regulation of Gene_expression of EDNRA 1 0.12 0.45 0.22
171 INT182265 EDN1 Positive_regulation of NOS2 1 0.24 0.56 0.22
172 INT36876 EDNRA Regulation of Negative_regulation of PRB1 1 0.00 0 0.21
173 INT112798 CASP1 Positive_regulation of CCL2 1 0.02 0.19 0.21
174 INT182263 EDN1 Positive_regulation of MMP1 1 0.15 0.43 0.21
175 INT57964 Myo5a Regulation of Negative_regulation of Cyp1a1 1 0.00 0.1 0.2
176 INT106825 Ednra Negative_regulation of Igf1 1 0.07 0.07 0.2
177 INT178074 EDN1 Positive_regulation of Phosphorylation of PXN 1 0.05 0.82 0.2
178 INT178086 Binding of EDNRA and PTK2 1 0.07 0.82 0.2
179 INT252814 ELANE Positive_regulation of Positive_regulation of CCL2 1 0.05 0.8 0.2
180 INT59459 Binding of OXTR and ISYNA1 1 0.05 0.47 0.2
181 INT274094 EDN1 Positive_regulation of AGT 1 0.16 0.95 0.2
182 INT306108 CCL2 Positive_regulation of Positive_regulation of Mapk3 1 0.03 0.15 0.2
183 INT252782 ROS1 Positive_regulation of Positive_regulation of CCL2 1 0.22 0.8 0.2
184 INT182258 EDN1 Positive_regulation of Positive_regulation of MMP1 1 0.15 0.47 0.19
185 INT182271 EDN1 Positive_regulation of Localization of MMP13 1 0.27 0.47 0.19
186 INT219915 Edn1 Regulation of Positive_regulation of Trpv1 1 0.33 0 0.18
187 INT140096 Gtf3a Positive_regulation of Gene_expression of Edn1 1 0.02 0.44 0.18
188 INT184540 Agt Regulation of Gene_expression of Ccl2 1 0.08 1.66 0.18
189 INT60778 Edn1 Positive_regulation of EDNRA 1 0.00 0 0.18
190 INT140094 Ifng Regulation of Gene_expression of Edn1 1 0.18 0.44 0.18
191 INT178073 EDN1 Positive_regulation of PTK2 1 0.03 1.02 0.17
192 INT116440 LY9 Negative_regulation of Gene_expression of CCL2 1 0.14 0.09 0.16
193 INT203759 Binding of EDN1 and TNF 1 0.16 0.71 0.16
194 INT94022 Positive_regulation of Binding of EDN1 and INSRR 1 0.06 0 0.16
195 INT178079 EDN1 Positive_regulation of Positive_regulation of AKT1 1 0.05 0.91 0.16
196 INT303941 CCL2 Positive_regulation of Protein_catabolism of GLI2 1 0.01 0 0.16
197 INT94021 Binding of EDN1 and EDN2 1 0.26 0 0.16
198 INT94014 Positive_regulation of Binding of EDN1 and EDN3 1 0.36 0 0.16
199 INT134196 Ahr Regulation of Transcription of Cyp1a1 1 0.11 0.14 0.16
200 INT106641 Binding of AVP and OXTR 1 0.22 0.47 0.16

Single Events

The table below shows the top 100 pain related interactions that have been reported for maternal process involved in parturition. They are ordered first by their pain relevance and then by number of times they were reported in maternal process involved in parturition. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02
2 INT82878 Gene_expression of Ccl2 201 0.78 164.95 101.35
3 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85
4 INT5781 Gene_expression of Edn1 190 0.78 99.1 46
5 INT81498 Positive_regulation of Gene_expression of CCL2 107 0.70 53.89 45.22
6 INT82883 Positive_regulation of Ccl2 105 0.69 84.96 42.27
7 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19
8 INT65698 Localization of CCL2 118 0.81 77.54 32.69
9 INT84170 Positive_regulation of Gene_expression of Ccl2 58 0.69 48.79 32.43
10 INT82882 Localization of Ccl2 61 0.80 41.96 28
11 INT23937 Gene_expression of EDNRA 103 0.65 55.63 24.67
12 INT6726 Positive_regulation of Edn1 118 0.70 65.96 24.07
13 INT8662 Positive_regulation of EDN1 144 0.70 125.34 19.59
14 INT5048 Binding of Edn1 55 0.47 18.86 19.16
15 INT66857 Regulation of CCL2 39 0.53 28.55 18.35
16 INT84171 Negative_regulation of Gene_expression of Ccl2 30 0.58 26.37 18.28
17 INT55880 Negative_regulation of Gene_expression of CCL2 49 0.59 22.37 18.09
18 INT55878 Regulation of Gene_expression of CCL2 34 0.62 15.71 17.97
19 INT6728 Gene_expression of Ednra 43 0.65 13.41 17.38
20 INT129 Localization of OXTR 51 0.80 11.08 15.36
21 INT9191 Localization of EDN1 94 0.81 57.01 14.78
22 INT8904 Positive_regulation of Gene_expression of EDN1 66 0.70 65.4 14.42
23 INT5806 Regulation of Edn1 63 0.62 23.46 13.88
24 INT6365 Localization of Edn1 56 0.81 18.84 13.83
25 INT21979 Negative_regulation of EDN1 52 0.58 24.65 12.55
26 INT96850 Negative_regulation of CCL2 42 0.59 24.89 12.55
27 INT70905 Positive_regulation of EDNRA 49 0.67 24.33 11.79
28 INT1708 Gene_expression of OXTR 56 0.78 6.92 10.69
29 INT10184 Regulation of EDN1 44 0.62 23.78 10.06
30 INT83450 Positive_regulation of Localization of CCL2 28 0.70 22.14 9.83
31 INT106200 Binding of Ccl2 22 0.42 16.7 9.75
32 INT78038 Gene_expression of Oxtr 43 0.78 18.72 9.38
33 INT6727 Positive_regulation of Ednra 27 0.64 18.75 8.71
34 INT10237 Binding of EDN1 40 0.48 16 8.48
35 INT30382 Negative_regulation of Ednra 21 0.42 12.06 8.19
36 INT54978 Binding of EDNRA 36 0.41 14.97 7.86
37 INT6957 Positive_regulation of OXTR 38 0.70 6.55 7.81
38 INT10899 Positive_regulation of Gene_expression of Edn1 32 0.70 24.88 7.65
39 INT10104 Negative_regulation of Edn1 43 0.59 15.63 7.2
40 INT82881 Regulation of Ccl2 19 0.57 15.29 7.19
41 INT81493 Transcription of CCL2 20 0.65 13.63 6.78
42 INT120895 Binding of CCL2 22 0.37 15.86 6.55
43 INT92504 Negative_regulation of Ccl2 17 0.43 8.98 6.29
44 INT69974 Positive_regulation of Oxtr 30 0.70 2.44 5.73
45 INT185 Regulation of Cyp1a1 18 0.54 2.71 5.56
46 INT83290 Regulation of Gene_expression of Ccl2 8 0.59 9.06 5.56
47 INT70907 Negative_regulation of EDNRA 30 0.36 19.68 5.49
48 INT60776 Regulation of EDNRA 20 0.51 16.62 5.36
49 INT2435 Negative_regulation of Cyp1a1 15 0.58 3.32 5.16
50 INT186 Positive_regulation of Cyp1a1 30 0.70 5 5.02
51 INT130 Negative_regulation of OXTR 19 0.43 4.63 4.96
52 INT21650 Regulation of OXTR 29 0.61 5.99 4.91
53 INT103073 Positive_regulation of Positive_regulation of Ccl2 10 0.50 6.74 4.7
54 INT96851 Negative_regulation of Localization of CCL2 14 0.53 5.98 4.57
55 INT21953 Binding of Ednra 12 0.33 4.72 4.56
56 INT75440 Regulation of Binding of Edn1 4 0.38 1.41 4.33
57 INT78033 Positive_regulation of Gene_expression of Oxtr 10 0.70 2.5 4.15
58 INT17975 Positive_regulation of Localization of OXTR 11 0.69 1.72 3.72
59 INT117518 Transcription of Ccl2 12 0.68 11.12 3.61
60 INT95272 Regulation of Gene_expression of Edn1 19 0.53 17.85 3.42
61 INT115203 Negative_regulation of Positive_regulation of Ednra 5 0.33 1.27 3.32
62 INT49971 Regulation of Ednra 10 0.35 2.4 3.06
63 INT19206 Regulation of Gene_expression of OXTR 5 0.62 0.58 2.96
64 INT93058 Positive_regulation of Gene_expression of Ednra 8 0.28 4.11 2.88
65 INT128 Negative_regulation of Localization of OXTR 7 0.59 2.92 2.86
66 INT22212 Gene_expression of CYP1A1 34 0.76 10.11 2.77
67 INT100014 Negative_regulation of Gene_expression of EDN1 17 0.42 7.85 2.71
68 INT117519 Positive_regulation of Transcription of Ccl2 5 0.49 6.01 2.54
69 INT6638 Binding of Oxtr 14 0.34 1.52 2.43
70 INT30857 Binding of OXTR 10 0.48 2.27 2.42
71 INT82880 Positive_regulation of Localization of Ccl2 4 0.49 2.65 2.31
72 INT55853 Positive_regulation of Positive_regulation of Edn1 11 0.61 6.5 2.21
73 INT113906 Regulation of Positive_regulation of CCL2 4 0.27 3.2 2.17
74 INT128993 Negative_regulation of Localization of Ccl2 1 0.42 1.5 2.1
75 INT49253 Regulation of Gene_expression of EDN1 11 0.61 3.92 2.07
76 INT113907 Regulation of Localization of CCL2 5 0.62 2.46 2.05
77 INT156677 Regulation of Gene_expression of Ednra 4 0.15 0.25 2.05
78 INT36267 Positive_regulation of CYP1A1 29 0.69 11.09 2.01
79 INT19409 Binding of Cyp1a1 12 0.48 2.58 1.97
80 INT100490 Negative_regulation of Positive_regulation of CCL2 6 0.23 1.48 1.96
81 INT49259 Regulation of Localization of EDN1 8 0.61 6.29 1.92
82 INT67980 Positive_regulation of Positive_regulation of CCL2 7 0.49 5.89 1.85
83 INT79815 Positive_regulation of Localization of Edn1 7 0.68 2.07 1.79
84 INT8661 Positive_regulation of Positive_regulation of EDN1 10 0.66 10.9 1.76
85 INT173700 Negative_regulation of Binding of Edn1 2 0.58 0.41 1.76
86 INT14842 Negative_regulation of Binding of EDN1 4 0.57 0.67 1.66
87 INT12062 Positive_regulation of Gene_expression of OXTR 9 0.69 1.04 1.63
88 INT72021 Localization of Ednra 7 0.58 3.13 1.53
89 INT181579 Phosphorylation of Edn1 1 0.71 8.59 1.51
90 INT24768 Negative_regulation of Gene_expression of Edn1 10 0.43 2.85 1.48
91 INT23938 Positive_regulation of Gene_expression of EDNRA 8 0.45 9.82 1.47
92 INT129488 Regulation of Gene_expression of EDNRA 5 0.51 3.39 1.44
93 INT322712 Negative_regulation of Binding of Ccl2 4 0.32 1.29 1.44
94 INT78034 Localization of Oxtr 7 0.81 1.09 1.36
95 INT17862 Localization of Cyp1a1 5 0.74 0.34 1.34
96 INT13674 Gene_expression of Cyp1a1 13 0.65 2.22 1.25
97 INT81497 Positive_regulation of Transcription of CCL2 4 0.63 2 1.25
98 INT49258 Negative_regulation of Positive_regulation of EDN1 10 0.43 7.24 1.12
99 INT294735 Positive_regulation of Binding of Ccl2 2 0.34 0.69 1.11
100 INT78032 Regulation of Oxtr 12 0.62 0.72 1.09
101 INT68220 Binding of CYP1A1 8 0.48 0.8 0.99
102 INT69803 Regulation of Localization of Edn1 3 0.62 0.79 0.98
103 INT72024 Localization of EDNRA 11 0.57 8.22 0.96
104 INT49255 Protein_catabolism of EDN1 5 0.99 2.66 0.95
105 INT69422 Positive_regulation of Negative_regulation of EDN1 2 0.43 0.96 0.95
106 INT49254 Transcription of EDN1 5 0.69 2.42 0.94
107 INT21651 Regulation of Regulation of OXTR 2 0.31 0.57 0.93
108 INT178133 Negative_regulation of Positive_regulation of EDNRA 2 0.35 2.18 0.88
109 INT61591 Negative_regulation of Localization of EDN1 11 0.59 2.09 0.85
110 INT61329 Positive_regulation of Positive_regulation of OXTR 1 0.38 0.49 0.85
111 INT85182 Transcription of Oxtr 5 0.68 1.27 0.83
112 INT57433 Positive_regulation of Binding of EDN1 3 0.49 0.62 0.82
113 INT117552 Regulation of Regulation of CCL2 1 0.13 0.57 0.8
114 INT61121 Regulation of Regulation of Edn1 1 0.43 0.2 0.75
115 INT66961 Regulation of Localization of OXTR 3 0.24 0 0.73
116 INT120010 Negative_regulation of Transcription of CCL2 1 0.02 0.99 0.72
117 INT59970 Positive_regulation of Binding of Edn1 2 0.40 1.11 0.71
118 INT313697 Phosphorylation of Ednra 1 0.18 0 0.7
119 INT32758 Regulation of Negative_regulation of OXTR 1 0.27 0 0.7
120 INT21957 Negative_regulation of Negative_regulation of Edn1 5 0.43 1.34 0.69
121 INT352413 Phosphorylation of Ccl2 1 0.42 0 0.69
122 INT49252 Positive_regulation of Localization of EDN1 17 0.69 6.55 0.66
123 INT100396 Transcription of Edn1 7 0.69 2.48 0.66
124 INT49256 Regulation of Positive_regulation of EDN1 2 0.45 2.5 0.65
125 INT136363 Negative_regulation of Positive_regulation of Ccl2 3 0.32 1.46 0.64
126 INT105484 Protein_catabolism of OXTR 3 0.90 0.73 0.59
127 INT222998 Positive_regulation of Negative_regulation of CCL2 1 0.12 1.11 0.59
128 INT7153 Positive_regulation of Regulation of Edn1 2 0.35 1.97 0.57
129 INT135715 Negative_regulation of Localization of Edn1 5 0.42 1.7 0.56
130 INT102776 Phosphorylation of CCL2 1 0.65 1.55 0.56
131 INT115826 Transcription of Cyp1a1 4 0.52 1.15 0.53
132 INT2438 Regulation of Regulation of Cyp1a1 1 0.27 0 0.52
133 INT186686 Regulation of Positive_regulation of EDNRA 5 0.22 2.35 0.51
134 INT181581 Regulation of Positive_regulation of Edn1 4 0.23 3.76 0.51
135 INT126442 Negative_regulation of Gene_expression of Ednra 3 0.33 1.94 0.51
136 INT302877 Regulation of Localization of Ccl2 2 0.19 1.08 0.49
137 INT115202 Positive_regulation of Positive_regulation of Ednra 2 0.39 2.88 0.49
138 INT120405 Phosphorylation of EDNRA 1 0.61 0.38 0.48
139 INT29880 Negative_regulation of Positive_regulation of OXTR 2 0.38 0.34 0.47
140 INT281138 Regulation of Binding of Ccl2 1 0.07 0.92 0.47
141 INT78035 Regulation of Gene_expression of Oxtr 5 0.62 0.26 0.46
142 INT78037 Positive_regulation of Positive_regulation of Oxtr 4 0.69 0.26 0.46
143 INT290397 Positive_regulation of Binding of CCL2 1 0.22 0.99 0.46
144 INT57434 Regulation of Regulation of EDN1 1 0.40 0.47 0.44
145 INT119574 Regulation of Regulation of Ccl2 1 0.04 0.35 0.43
146 INT63100 Phosphorylation of OXTR 2 0.73 0.63 0.42
147 INT134259 Negative_regulation of Transcription of Ccl2 2 0.11 0.93 0.42
148 INT158057 Positive_regulation of Positive_regulation of EDNRA 2 0.15 0 0.41
149 INT27414 Positive_regulation of Negative_regulation of Cyp1a1 1 0.49 0.44 0.41
150 INT81433 Negative_regulation of Positive_regulation of Edn1 4 0.39 0.81 0.38
151 INT115835 Negative_regulation of Positive_regulation of Cyp1a1 2 0.32 1.35 0.36
152 INT113368 Regulation of Negative_regulation of Edn1 1 0.45 0.71 0.35
153 INT29881 Negative_regulation of Negative_regulation of OXTR 1 0.35 0 0.34
154 INT109497 Negative_regulation of Binding of Oxtr 2 0.39 0.05 0.33
155 INT115409 Regulation of Binding of Oxtr 1 0.12 0 0.31
156 INT72022 Positive_regulation of Localization of Ednra 2 0.32 0.07 0.3
157 INT350970 Negative_regulation of Binding of EDNRA 1 0.41 0.86 0.29
158 INT13676 Negative_regulation of Gene_expression of Cyp1a1 1 0.33 0.1 0.29
159 INT96886 Positive_regulation of Gene_expression of CYP1A1 8 0.64 3.15 0.27
160 INT99628 Positive_regulation of Gene_expression of Cyp1a1 4 0.25 1.3 0.27
161 INT115926 Negative_regulation of Positive_regulation of CYP1A1 1 0.30 0.16 0.27
162 INT84038 Protein_catabolism of Edn1 2 0.86 0.69 0.26
163 INT52176 Positive_regulation of Binding of Cyp1a1 1 0.44 0 0.26
164 INT115834 Positive_regulation of Transcription of Cyp1a1 2 0.38 0.64 0.23
165 INT116673 Phosphorylation of Oxtr 1 0.40 0.1 0.22
166 INT116674 Negative_regulation of Phosphorylation of Oxtr 1 0.21 0.1 0.22
167 INT302487 Negative_regulation of Gene_expression of OXTR 1 0.02 0.54 0.21
168 INT67265 Positive_regulation of Negative_regulation of Edn1 1 0.61 0.05 0.21
169 INT65885 Negative_regulation of CYP1A1 2 0.18 0.64 0.2
170 INT96884 Regulation of Gene_expression of CYP1A1 2 0.60 0.54 0.2
171 INT96889 Negative_regulation of Gene_expression of CYP1A1 2 0.42 0.9 0.2
172 INT156920 Phosphorylation of EDN1 4 0.61 0.66 0.19
173 INT58763 Regulation of Positive_regulation of OXTR 2 0.42 0.12 0.18
174 INT72023 Positive_regulation of Localization of EDNRA 1 0.02 0.07 0.18
175 INT72025 Negative_regulation of Localization of EDNRA 1 0.01 0.07 0.18
176 INT72020 Negative_regulation of Localization of Ednra 1 0.24 0.07 0.18
177 INT173335 Negative_regulation of Gene_expression of EDNRA 2 0.19 0.71 0.17
178 INT134195 Regulation of Transcription of Cyp1a1 1 0.13 0.14 0.16
179 INT306938 Regulation of Transcription of CCL2 1 0.05 0.81 0.13
180 INT284152 Regulation of Transcription of EDN1 1 0.32 0.44 0.13
181 INT239550 Negative_regulation of Binding of CCL2 1 0.18 0 0.13
182 INT155668 Negative_regulation of Oxtr 2 0.50 0.28 0.12
183 INT17866 Positive_regulation of Localization of Cyp1a1 1 0.49 0 0.12
184 INT70908 Transcription of EDNRA 1 0.08 0.33 0.12
185 INT349935 Transcription of CYP1A1 1 0.47 1.22 0.12
186 INT70906 Negative_regulation of Transcription of EDNRA 1 0.05 0.33 0.12
187 INT68218 Regulation of Positive_regulation of CYP1A1 3 0.45 2.35 0.1
188 INT100781 Positive_regulation of Regulation of OXTR 1 0.50 0.49 0.1
189 INT17863 Regulation of Positive_regulation of Cyp1a1 1 0.27 0 0.09
190 INT184550 Positive_regulation of Regulation of Ccl2 1 0.46 1.11 0.09
191 INT328841 Transcription of OXTR 1 0.10 0.62 0.09
192 INT49257 Positive_regulation of Transcription of EDN1 2 0.46 1.1 0.08
193 INT85183 Regulation of Transcription of Oxtr 1 0.12 0.17 0.08
194 INT126441 Negative_regulation of Transcription of Edn1 1 0.40 0.17 0.08
195 INT78036 Negative_regulation of Regulation of Oxtr 1 0.43 0 0.08
196 INT78039 Negative_regulation of Positive_regulation of Oxtr 1 0.43 0 0.08
197 INT85184 Negative_regulation of Gene_expression of Oxtr 2 0.26 1.19 0.07
198 INT274054 Localization of CYP1A1 1 0.12 0 0.07
199 INT274056 Protein_catabolism of CYP1A1 1 0.15 0 0.06
200 INT68219 Positive_regulation of Binding of CYP1A1 1 0.50 0 0.05
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