GO:0060155

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Name platelet dense granule organization
Categary Process
Go Slim No
Go Link GO:0060155
Unique Molecular Interactions 73
Total Molecular Interactions 92
Total Single Events 521
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for platelet dense granule organization. They are ordered first by their pain relevance and then by number of times they were reported for platelet dense granule organization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT80199 Ngf Regulation of Transcription of Rab38 1 0.01 1.48 1.68
2 INT351366 LPA Positive_regulation of Rab38 1 0.00 0.95 1.53
3 INT80200 Negative_regulation of Ngf Negative_regulation of Gene_expression of Rab38 1 0.01 0.68 0.8
4 INT284481 Binding of ABCA1 and Ighg1 1 0.00 1.39 0.7
5 INT150338 Binding of F2 and F2R 1 0.11 0.4 0.67
6 INT125699 CR1 Negative_regulation of Positive_regulation of ABCA1 1 0.03 0.64 0.53
7 INT345308 Binding of ABCA1 and TIMP2 1 0.00 0.21 0.52
8 INT187114 TIMP2 Negative_regulation of ABCA1 1 0.02 0.28 0.51
9 INT187108 TIMP1 Negative_regulation of ABCA1 1 0.02 0.28 0.51
10 INT193480 Binding of ABCA1 and IRF6 1 0.00 1.08 0.46
11 INT124088 Rab38 Negative_regulation of Mapk14 1 0.00 0.89 0.42
12 INT104992 Ptger3 Regulation of Rab38 1 0.02 0.79 0.38
13 INT123663 F2R Positive_regulation of MAPK14 1 0.12 0.42 0.26
14 INT123662 Negative_regulation of F2R Positive_regulation of MAPK14 1 0.08 0.42 0.26
15 INT239337 Abca1 Positive_regulation of RCT 1 0.07 3.11 0.24
16 INT123660 F2R Positive_regulation of PAR1 2 0.10 1.96 0.22
17 INT112205 Pck1 Regulation of Rab38 1 0.00 0 0.2
18 INT123664 F2R Positive_regulation of PAR4 1 0.03 0.51 0.19
19 INT239316 Nr1h2 Positive_regulation of Transcription of Abca1 1 0.15 0.67 0.18
20 INT335046 PPARA Positive_regulation of Gene_expression of ABCA1 1 0.33 0.25 0.18
21 INT207345 PTGDS Negative_regulation of Gene_expression of ABCA1 1 0.21 0 0.17
22 INT207359 ZNF398 Negative_regulation of ABCA1 1 0.01 0 0.17
23 INT208360 Binding of Abca1 and Apoe 1 0.15 0.74 0.17
24 INT207344 PTGER2 Negative_regulation of Gene_expression of ABCA1 1 0.04 0 0.17
25 INT207350 TBXA2R Regulation of Gene_expression of ABCA1 1 0.10 0 0.17
26 INT207338 Negative_regulation of CPOX Negative_regulation of ABCA1 1 0.11 0 0.16
27 INT335459 ABCA1 Positive_regulation of ITPR3 1 0.00 0 0.15
28 INT156531 Binding of ABCA1 and HSD11B1 1 0.22 1.06 0.14
29 INT207360 PTGDS Negative_regulation of Negative_regulation of ABCA1 1 0.25 0 0.14
30 INT207337 PTGER2 Negative_regulation of Negative_regulation of ABCA1 1 0.04 0 0.14
31 INT207353 ZNF398 Regulation of ABCA1 1 0.00 0 0.14
32 INT234104 Binding of Snap25 and DTNBP1 1 0.29 0.09 0.13
33 INT344706 Nr1h2 Regulation of Abca1 1 0.03 2.39 0.12
34 INT293236 IDO1 Regulation of ABCA1 1 0.00 0 0.11
35 INT262255 Binding of APC and F2R 1 0.05 3 0.1
36 INT42224 ABCA1 Positive_regulation of CYBB 1 0.01 0 0.09
37 INT42225 Binding of ABCA1 and DECR1 1 0.02 0 0.08
38 INT289258 Binding of ABCA1 and Il6ra 1 0.00 0.33 0.07
39 INT262175 Nr1i2 Positive_regulation of Gene_expression of Abca1 1 0.24 0.21 0.06
40 INT229423 Atp6v0a2 Regulation of Rab38 1 0.00 1.73 0.06
41 INT293233 IDO1 Positive_regulation of ABCA1 1 0.01 0 0.06
42 INT339583 Binding of ABCA1 and RPE 1 0.03 1.38 0.05
43 INT339587 Positive_regulation of Binding of ABCA1 and RPE 1 0.04 1.38 0.05
44 INT188432 Negative_regulation of Binding of ABCA1 and IL6 1 0.02 0.47 0.05
45 INT188431 Binding of ABCA1 and IL6 1 0.02 0.47 0.05
46 INT261728 PSMB6 Negative_regulation of Transcription of F2R 1 0.01 0.17 0.03
47 INT175628 F2R Positive_regulation of F2RL1 1 0.04 1.46 0.03
48 INT230136 OSBPL8 Regulation of Binding of ABCA1 1 0.07 0.17 0.03
49 INT207343 Negative_regulation of CPOX Negative_regulation of Gene_expression of ABCA1 1 0.09 0 0.03
50 INT284392 Binding of ABCA1 and Vegfa 1 0.00 0.71 0
51 INT261729 COL5A2 Regulation of Gene_expression of F2R 1 0.18 0 0
52 INT229927 CD59 Negative_regulation of Binding of ABCA1 1 0.01 0 0
53 INT229923 Binding of ABCA1 and C9 1 0.00 0.74 0
54 INT284372 Binding of ABCA1 and AMT 1 0.00 0 0
55 INT239341 Binding of Abca1 and Hdl1 1 0.04 4.78 0
56 INT297056 Binding of ABCA1 and Oas1b 1 0.00 0.13 0
57 INT117795 ABCA1 Regulation of GHRL 1 0.00 0 0
58 INT284393 Positive_regulation of Binding of ABCA1 and Vegfa 1 0.00 0.36 0
59 INT326085 Prkaca Regulation of Phosphorylation of ABCA1 1 0.02 0.44 0
60 INT229981 Binding of ABCA1 and Cdca3 1 0.00 0.74 0
61 INT261732 F2 Positive_regulation of F2R 1 0.14 0 0
62 INT144760 Binding of ABCA1 and Insr 1 0.00 0 0
63 INT339580 TIMP3 Positive_regulation of ABCA1 1 0.16 0.73 0
64 INT234098 Positive_regulation of Binding of Gopc and Dtnbp1 1 0.27 0 0
65 INT326060 Binding of ABCA1 and APOA1 1 0.39 1.5 0
66 INT307283 Binding of ABCA1 and PMP2 1 0.00 0 0
67 INT234097 Binding of Gopc and Dtnbp1 1 0.20 0 0
68 INT326084 Prkaca Positive_regulation of Phosphorylation of ABCA1 1 0.06 0.44 0
69 INT217396 Binding of Abca1 and App 1 0.26 0.83 0
70 INT344712 Nr1h3 Regulation of Abca1 1 0.03 1.68 0
71 INT239321 Binding of Abca1 and Apoa1 1 0.11 1.61 0
72 INT261730 ROCK1 Positive_regulation of Positive_regulation of F2R 1 0.37 0 0
73 INT261735 Positive_regulation of F2 Positive_regulation of F2R 1 0.14 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for platelet dense granule organization. They are ordered first by their pain relevance and then by number of times they were reported in platelet dense granule organization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT49089 Gene_expression of Rab38 22 0.45 6.79 13.76
2 INT49087 Positive_regulation of Rab38 20 0.00 8.01 12
3 INT36453 Binding of ABCA1 48 0.45 19.9 10.84
4 INT28312 Gene_expression of ABCA1 85 0.72 37.69 9.27
5 INT9968 Negative_regulation of Rab38 15 0.00 10.45 8.64
6 INT25467 Regulation of Rab38 19 0.00 8.68 6.73
7 INT2848 Localization of ABCA1 23 0.70 10.64 4.73
8 INT18670 Negative_regulation of ABCA1 16 0.54 5.8 3.39
9 INT25466 Binding of Rab38 6 0.00 2.23 3.28
10 INT28130 Positive_regulation of ABCA1 18 0.61 7.08 3.22
11 INT150339 Gene_expression of F2R 10 0.73 3.59 2.46
12 INT190081 Gene_expression of Abca1 21 0.65 18.18 2.45
13 INT80194 Transcription of Rab38 4 0.04 1.85 2.35
14 INT234090 Gene_expression of Dtnbp1 11 0.67 3.09 1.86
15 INT207370 Negative_regulation of Gene_expression of ABCA1 1 0.54 2.75 1.78
16 INT80195 Regulation of Gene_expression of Rab38 2 0.04 2.23 1.66
17 INT145201 Negative_regulation of Binding of Rab38 1 0.37 0.06 1.61
18 INT155801 Negative_regulation of Dtnbp1 4 0.59 3.97 1.5
19 INT146659 Negative_regulation of Negative_regulation of Rab38 1 0.00 0.45 1.3
20 INT111935 Negative_regulation of Positive_regulation of Rab38 2 0.08 1.37 1.09
21 INT239302 Positive_regulation of Gene_expression of Abca1 9 0.32 9.1 1.06
22 INT234087 Negative_regulation of Gene_expression of Dtnbp1 4 0.42 2.07 1.05
23 INT21546 Regulation of ABCA1 16 0.40 4.21 1.04
24 INT49088 Positive_regulation of Gene_expression of Rab38 1 0.12 0.17 1.02
25 INT145200 Positive_regulation of Binding of Rab38 1 0.59 0.07 0.99
26 INT234079 Positive_regulation of Dtnbp1 4 0.61 1.29 0.85
27 INT155803 Transcription of Dtnbp1 3 0.71 3.09 0.85
28 INT190089 Binding of Abca1 5 0.36 2.21 0.83
29 INT323368 Binding of Dtnbp1 1 0.48 6.03 0.79
30 INT135646 Negative_regulation of Transcription of Rab38 1 0.01 0.55 0.77
31 INT80192 Positive_regulation of Transcription of Rab38 1 0.01 0.58 0.77
32 INT164627 Positive_regulation of Gene_expression of ABCA1 9 0.61 3.95 0.67
33 INT155802 Negative_regulation of Transcription of Dtnbp1 3 0.58 2.26 0.63
34 INT123672 Positive_regulation of F2R 9 0.47 0.77 0.58
35 INT277710 Regulation of Localization of ABCA1 1 0.04 1.73 0.56
36 INT167468 Regulation of Gene_expression of ABCA1 5 0.52 0.08 0.43
37 INT323370 Regulation of Dtnbp1 1 0.45 0.83 0.42
38 INT209180 Transcription of ABCA1 4 0.47 1.09 0.39
39 INT345322 Regulation of Transcription of ABCA1 1 0.01 0 0.39
40 INT234102 Binding of DTNBP1 3 0.35 0.8 0.37
41 INT167122 Protein_catabolism of ABCA1 3 0.02 0.27 0.37
42 INT144981 Binding of F2R 3 0.36 1.66 0.35
43 INT323369 Negative_regulation of Negative_regulation of Dtnbp1 1 0.43 0.87 0.33
44 INT239295 Positive_regulation of Abca1 3 0.30 2.18 0.32
45 INT230435 Negative_regulation of DTNBP1 2 0.08 3.11 0.32
46 INT239279 Regulation of Gene_expression of Abca1 2 0.44 2.42 0.26
47 INT344685 Positive_regulation of Binding of Abca1 1 0.12 0.76 0.26
48 INT284385 Positive_regulation of Localization of ABCA1 2 0.02 0.22 0.25
49 INT239287 Transcription of Abca1 1 0.32 1.87 0.21
50 INT300227 Positive_regulation of Binding of ABCA1 1 0.41 1.85 0.19
51 INT277709 Regulation of Binding of ABCA1 1 0.04 0.52 0.19
52 INT239308 Positive_regulation of Transcription of Abca1 1 0.28 0.67 0.18
53 INT234085 Localization of Dtnbp1 1 0.75 1.58 0.18
54 INT261745 Regulation of F2R 1 0.43 0.22 0.16
55 INT261739 Regulation of Gene_expression of F2R 1 0.26 0.22 0.16
56 INT217387 Regulation of Abca1 3 0.27 2.01 0.15
57 INT42227 Negative_regulation of Positive_regulation of ABCA1 1 0.03 0 0.09
58 INT42226 Positive_regulation of Positive_regulation of ABCA1 1 0.02 0 0.09
59 INT307530 Negative_regulation of Binding of F2R 1 0.03 0 0.09
60 INT262061 Negative_regulation of Gene_expression of Abca1 1 0.19 0.68 0.08
61 INT234101 Localization of DTNBP1 1 0.73 0.79 0.07
62 INT261737 Transcription of F2R 1 0.50 0.31 0.05
63 INT239296 Negative_regulation of Abca1 3 0.26 3.83 0.04
64 INT253595 Localization of Abca1 2 0.37 0.35 0.03
65 INT234103 Gene_expression of DTNBP1 1 0.58 0 0.03
66 INT229430 Localization of Rab38 1 0.01 0.75 0.03
67 INT326077 Positive_regulation of Transcription of ABCA1 1 0.41 0.22 0
68 INT326076 Phosphorylation of ABCA1 1 0.73 0.66 0
69 INT326083 Positive_regulation of Phosphorylation of ABCA1 1 0.61 0.66 0
70 INT261741 Negative_regulation of Positive_regulation of F2R 1 0.40 0 0
71 INT261743 Positive_regulation of Positive_regulation of F2R 1 0.44 0 0
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