GO:0060192

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Name negative regulation of lipase activity
Categary Process
Go Slim No
Go Link GO:0060192
Unique Molecular Interactions 61
Total Molecular Interactions 70
Total Single Events 620
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of lipase activity. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of lipase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT307781 Apoa1 Positive_regulation of LCAT 1 0.76 1.19 0.45
2 INT213027 Binding of Apoa1 and Scarb1 6 0.09 7.52 0.43
3 INT307780 Apoa1 Positive_regulation of Soat1 1 0.04 1.14 0.42
4 INT5935 Por Regulation of Oprm1 1 0.19 0.51 0.28
5 INT213029 Positive_regulation of Binding of Apoa1 and Scarb1 1 0.09 3.38 0.27
6 INT307207 Ppara Positive_regulation of Apoa2 1 0.10 0.94 0.25
7 INT189321 Binding of Apoa1 and Hdlcl1 1 0.00 0.68 0.2
8 INT43510 Apoa2 Positive_regulation of Localization of POMC 1 0.03 0 0.16
9 INT33752 Apoa2 Regulation of Localization of POMC 1 0.06 0 0.12
10 INT33750 Apoa2 Regulation of Agt 1 0.07 0 0.12
11 INT33751 Apoa2 Positive_regulation of Positive_regulation of POMC 1 0.09 0 0.11
12 INT2458 Apoa2 Positive_regulation of Localization of Avp 1 0.10 0 0.11
13 INT213042 Apoa1 Positive_regulation of Nos3 1 0.10 2.17 0.11
14 INT282094 Apoa2 Negative_regulation of BCL2 1 0.06 1.15 0.09
15 INT238472 Binding of AVP and POR 1 0.02 0.85 0.09
16 INT342232 Binding of POR and SEPP1 1 0.02 0.75 0.08
17 INT43121 Apoa2 Regulation of Smc1b 1 0.02 0 0.08
18 INT190885 Binding of Apoa2 and Hdl1 1 0.02 0.73 0.07
19 INT279652 PPARA Positive_regulation of Gene_expression of Apoa1 1 0.00 0.75 0.07
20 INT239348 Binding of Apoa1 and Hdl1 1 0.03 3.34 0.05
21 INT296023 Positive_regulation of Apoa2 Negative_regulation of APOA1 1 0.50 0.35 0.05
22 INT296024 Apoa2 Negative_regulation of CETP 1 0.39 0.35 0.05
23 INT43124 Apoa2 Positive_regulation of Positive_regulation of NA 1 0.07 0 0.05
24 INT296025 Apoa2 Negative_regulation of APOA1 1 0.47 0.35 0.05
25 INT236722 Ppara Positive_regulation of Binding of Apoa1 1 0.10 0.18 0.04
26 INT288908 Apoa1 Positive_regulation of Gene_expression of HSD11B1 1 0.03 0.53 0.04
27 INT325025 Apoa2 Positive_regulation of Hdl1 1 0.05 1.03 0.04
28 INT239345 Apoa1 Positive_regulation of RCT 1 0.02 1.15 0.03
29 INT308658 Binding of Apoa2 and Apoe 1 0.17 0.15 0.03
30 INT264979 Binding of POR and BAG3 1 0.15 0.38 0
31 INT10903 Apoa2 Positive_regulation of Nppb 1 0.08 0.17 0
32 INT239332 Hdl1 Positive_regulation of Gene_expression of Apoa1 1 0.04 0.84 0
33 INT47454 ras Positive_regulation of Apoa2 1 0.12 0.21 0
34 INT10907 Apoa2 Positive_regulation of Localization of Nppb 1 0.09 0.23 0
35 INT213017 Apoa1 Negative_regulation of Positive_regulation of Gtf3a 1 0.00 1.16 0
36 INT239353 CETP Regulation of Apoa1 1 0.16 0.65 0
37 INT239342 Lcat Regulation of Apoa1 1 0.16 0.65 0
38 INT213043 Regulation of Binding of Apoa1 and Scarb1 1 0.05 1.12 0
39 INT239321 Binding of Abca1 and Apoa1 1 0.11 1.61 0
40 INT239319 Pltp Regulation of Apoa1 1 0.22 0.65 0
41 INT239350 Eef1a2 Positive_regulation of Apoa1 1 0.22 0.86 0
42 INT304270 Binding of Apoa1 and Scarb1 1 0.00 0.39 0
43 INT185161 Binding of APOA2 and Retn 1 0.03 1.01 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of lipase activity. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of lipase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT8579 Gene_expression of Apoa1 13 0.76 35.89 7.21
2 INT19146 Negative_regulation of Apoa2 19 0.36 5.34 6.73
3 INT74614 Positive_regulation of Apoa1 16 0.68 23.95 5.04
4 INT181886 Gene_expression of Apoa1 40 0.64 40.53 4.56
5 INT2453 Positive_regulation of Apoa2 20 0.54 3.49 4.08
6 INT10830 Regulation of Apoa1 11 0.44 15.1 3.04
7 INT10556 Regulation of Apoa2 5 0.44 0.51 2.8
8 INT181880 Positive_regulation of Apoa1 19 0.66 21.19 2.43
9 INT38384 Regulation of Por 5 0.47 0.58 2.4
10 INT2452 Localization of Apoa2 9 0.55 0 2.3
11 INT12131 Gene_expression of POR 17 0.77 9.42 2.17
12 INT49313 Positive_regulation of Gene_expression of Apoa1 3 0.68 9.55 2.01
13 INT59302 Positive_regulation of POR 19 0.49 15.18 1.95
14 INT22863 Negative_regulation of Apoa1 10 0.57 10.68 1.86
15 INT21813 Gene_expression of Apoa2 10 0.61 3.68 1.81
16 INT156484 Binding of Apoa1 4 0.47 6.78 1.63
17 INT181881 Positive_regulation of Gene_expression of Apoa1 13 0.48 14.31 1.45
18 INT181882 Localization of Apoa1 8 0.71 7.94 1.37
19 INT151 Positive_regulation of Por 5 0.62 0.42 1.31
20 INT49013 Gene_expression of Por 6 0.75 2.19 1.22
21 INT181879 Negative_regulation of Apoa1 8 0.55 8.18 1.11
22 INT115821 Transcription of Por 1 0.33 0.51 1.02
23 INT49012 Regulation of Gene_expression of Por 1 0.44 0 1.02
24 INT180451 Positive_regulation of Apoa2 15 0.67 12.65 0.89
25 INT181885 Binding of Apoa1 7 0.35 5.66 0.84
26 INT58960 Regulation of POR 5 0.25 1.04 0.68
27 INT25374 Negative_regulation of Negative_regulation of Apoa2 1 0.30 0.24 0.67
28 INT181888 Regulation of Apoa1 5 0.26 5.07 0.6
29 INT213118 Negative_regulation of Gene_expression of Apoa1 2 0.42 2.86 0.6
30 INT10983 Binding of Apoa2 7 0.45 4.21 0.52
31 INT40164 Binding of Por 2 0.37 0.5 0.51
32 INT43397 Positive_regulation of Localization of Apoa2 1 0.09 0 0.48
33 INT190882 Regulation of Gene_expression of Apoa1 4 0.23 3.67 0.43
34 INT174753 Gene_expression of Apoa2 15 0.75 13.82 0.41
35 INT265 Negative_regulation of Por 4 0.59 0.34 0.41
36 INT181883 Negative_regulation of Negative_regulation of Apoa1 1 0.40 1.24 0.39
37 INT12249 Binding of POR 5 0.35 2.76 0.35
38 INT261209 Localization of Apoa1 4 0.73 2.61 0.33
39 INT47453 Positive_regulation of Positive_regulation of Apoa2 3 0.31 1.17 0.32
40 INT307779 Positive_regulation of Localization of Apoa1 1 0.49 0.88 0.31
41 INT43396 Regulation of Localization of Apoa2 1 0.09 0 0.3
42 INT12132 Positive_regulation of Gene_expression of POR 5 0.31 1.96 0.27
43 INT297322 Binding of Apoa2 3 0.36 1.7 0.27
44 INT67227 Positive_regulation of Binding of Apoa2 2 0.26 1.31 0.25
45 INT2450 Negative_regulation of Positive_regulation of Apoa2 1 0.21 0 0.24
46 INT2449 Negative_regulation of Localization of Apoa2 1 0.19 0 0.22
47 INT323965 Protein_catabolism of Apoa2 1 0.01 0.34 0.22
48 INT180454 Negative_regulation of Apoa2 6 0.42 7.42 0.2
49 INT190874 Negative_regulation of Gene_expression of Apoa1 1 0.15 0.9 0.2
50 INT10984 Negative_regulation of Binding of Apoa2 2 0.35 0.7 0.19
51 INT64189 Protein_catabolism of POR 1 0.37 0.16 0.18
52 INT239275 Regulation of Localization of Apoa1 1 0.19 1.62 0.18
53 INT67225 Positive_regulation of Gene_expression of Apoa2 2 0.28 1.3 0.17
54 INT252219 Negative_regulation of Binding of Apoa1 1 0.16 0.95 0.15
55 INT115825 Positive_regulation of Gene_expression of Por 2 0.22 0.47 0.12
56 INT264861 Regulation of Apoa2 5 0.44 4.25 0.11
57 INT167018 Negative_regulation of POR 3 0.37 1.9 0.11
58 INT279650 Transcription of Apoa2 1 0.02 0.79 0.1
59 INT279651 Positive_regulation of Transcription of Apoa2 1 0.02 0.84 0.1
60 INT180452 Localization of Apoa2 2 0.73 2.83 0.09
61 INT115833 Negative_regulation of Transcription of Por 1 0.20 0.52 0.09
62 INT115828 Negative_regulation of Gene_expression of Por 1 0.20 0.52 0.09
63 INT67224 Negative_regulation of Gene_expression of Apoa2 1 0.32 0.47 0.08
64 INT282084 Negative_regulation of Gene_expression of Apoa2 1 0.04 1.17 0.07
65 INT67226 Regulation of Gene_expression of Apoa2 1 0.15 0.51 0.07
66 INT67606 Localization of POR 3 0.68 1.22 0.06
67 INT35232 Regulation of Positive_regulation of Apoa2 1 0.48 0.18 0.05
68 INT335124 Positive_regulation of APOA2 1 0.15 0.43 0.05
69 INT325024 Regulation of Gene_expression of Apoa2 1 0.21 1.23 0.03
70 INT323616 Phosphorylation of POR 1 0.05 0.7 0
71 INT308624 Positive_regulation of Gene_expression of Apoa2 1 0.49 0.49 0
72 INT323617 Positive_regulation of Phosphorylation of POR 1 0.03 0.7 0
73 INT264980 Transcription of POR 1 0.38 0.73 0
74 INT180453 Positive_regulation of Localization of Apoa2 1 0.49 1.84 0
75 INT309803 Negative_regulation of Binding of Apoa2 1 0.41 1.02 0
76 INT213117 Negative_regulation of Positive_regulation of Apoa1 1 0.07 0.54 0
77 INT308631 Negative_regulation of Positive_regulation of Apoa2 1 0.42 0.5 0
78 INT309802 Positive_regulation of Binding of Apoa2 1 0.49 1.03 0
79 INT288894 Regulation of Localization of Apoa1 1 0.14 0.42 0
80 INT191529 Negative_regulation of Positive_regulation of POR 1 0.02 1.5 0
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