GO:0060253

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Name negative regulation of glial cell proliferation
Categary Process
Go Slim No
Go Link GO:0060253
Unique Molecular Interactions 132
Total Molecular Interactions 183
Total Single Events 1124
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of glial cell proliferation. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of glial cell proliferation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT93470 Notch1 Positive_regulation of Localization of Prkcg 2 0.09 0.31 1.65
2 INT142207 Adcyap1 Positive_regulation of Localization of Gh 1 0.07 0 1.3
3 INT69279 Regulation of Binding of TSPO and Gabrg1 1 0.00 2.05 1.26
4 INT99695 Binding of Tspo and Insrr 1 0.02 0.52 1.25
5 INT74467 Adcyap1 Positive_regulation of Localization of Gh1 1 0.37 0 1.25
6 INT59606 Binding of Tspo and Penk 1 0.04 0 1.12
7 INT48260 Binding of Adcyap1 and Calca 1 0.35 0 1.04
8 INT210015 Binding of Adcyap1 and Crh 1 0.47 0.88 1
9 INT310348 Binding of Tspo and Gabrd 1 0.00 0.43 0.88
10 INT120825 Adcyap1 Positive_regulation of Localization of Nos1 1 0.26 0.62 0.85
11 INT142208 Adcyap1 Positive_regulation of Transcription of Gh 1 0.05 0 0.77
12 INT142210 Adcyap1 Positive_regulation of Gh 1 0.05 0 0.77
13 INT74468 Adcyap1 Positive_regulation of Localization of Gnrhr 1 0.27 0 0.67
14 INT142209 Adcyap1 Positive_regulation of Gene_expression of Gh 1 0.05 0 0.63
15 INT69280 Negative_regulation of Binding of TSPO and Gabrg1 1 0.00 1.03 0.63
16 INT69278 Binding of TSPO and Gabrg1 1 0.00 1.01 0.62
17 INT59155 Binding of Adcyap1 and Vip 2 0.34 0.08 0.55
18 INT142206 Negative_regulation of Adcyap1 Positive_regulation of Gh 1 0.04 0 0.54
19 INT106662 Adcyap1 Regulation of Penk 1 0.00 0 0.49
20 INT106664 Adcyap1 Regulation of Gene_expression of Vip 1 0.00 0 0.49
21 INT106663 Adcyap1 Regulation of Vip 1 0.00 0 0.49
22 INT57391 Binding of Tspo and Oprl1 1 0.18 0.16 0.49
23 INT165078 Binding of CTSB and Notch1 1 0.00 1.08 0.48
24 INT148377 PDP1 Positive_regulation of NOTCH1 1 0.44 0.64 0.44
25 INT148378 CP Positive_regulation of NOTCH1 1 0.11 0.64 0.44
26 INT244280 Binding of Tspo and Ptz1a 1 0.02 0.49 0.41
27 INT190739 Adcyap1 Regulation of Gene_expression of Scn2a1 1 0.13 0 0.39
28 INT273045 Vip Regulation of Adcyap1 1 0.17 0.5 0.38
29 INT187230 Binding of Adcyap1 and Vipr1 1 0.11 0.92 0.38
30 INT187228 Binding of Adcyap1 and Vipr2 1 0.11 0.91 0.38
31 INT52632 Binding of TSPO and CCK 1 0.15 0.53 0.37
32 INT190751 Adcyap1 Positive_regulation of Vipr2 2 0.16 1.02 0.36
33 INT315385 Adcyap1 Positive_regulation of Phosphorylation of Bad 1 0.05 0.44 0.32
34 INT284689 Binding of Tspo and Map3k12 1 0.00 0.59 0.32
35 INT315387 Adcyap1 Positive_regulation of Phosphorylation of Gopc 1 0.03 0.44 0.32
36 INT84426 Binding of TSPO and INSRR 1 0.01 0.22 0.3
37 INT139125 Adcyap1 Regulation of Ier3 1 0.54 0.8 0.29
38 INT158922 Positive_regulation of Binding of TSPO and Tspo 1 0.54 0.83 0.28
39 INT58898 Adcyap1 Regulation of Localization of Acot1 1 0.17 0 0.28
40 INT158923 Binding of TSPO and Tspo 1 0.40 0.82 0.28
41 INT63654 VIP Positive_regulation of Adcyap1 1 0.27 0.15 0.27
42 INT74118 Adcyap1 Positive_regulation of Localization of Avp 1 0.33 0 0.26
43 INT106658 Adcyap1 Positive_regulation of Gene_expression of Npy 1 0.54 0.16 0.25
44 INT106660 Adcyap1 Positive_regulation of Gene_expression of Chga 1 0.54 0.16 0.25
45 INT190741 Adcyap1 Positive_regulation of Gria2 1 0.00 0 0.24
46 INT69073 Adcyap1 Regulation of Localization of Gnrh1 2 0.66 0 0.22
47 INT273046 Vip Negative_regulation of Gene_expression of Adcyap1 1 0.20 1.14 0.21
48 INT190745 Adcyap1 Regulation of Car2 1 0.08 0 0.21
49 INT297545 Pou3f3 Regulation of Hes1 1 0.05 0.41 0.2
50 INT315384 Adcyap1 Negative_regulation of Positive_regulation of Casp3 1 0.02 0.53 0.2
51 INT315386 Adcyap1 Positive_regulation of Bad 1 0.03 0.52 0.2
52 INT80049 Adcyap1 Positive_regulation of Positive_regulation of Slc4a4 1 0.19 0 0.2
53 INT273048 Adcyap1 Positive_regulation of Adcyap1r1 1 0.11 1.02 0.19
54 INT315396 Adcyap1 Regulation of IFNA1 1 0.02 0.14 0.17
55 INT190749 Adcyap1 Positive_regulation of Vipr1 1 0.11 0 0.17
56 INT190744 Adcyap1 Positive_regulation of Car2 1 0.10 0.08 0.16
57 INT191336 Binding of TSPO and GOPC 1 0.01 0.65 0.16
58 INT191338 Binding of TSPO and IDO1 1 0.02 0.65 0.16
59 INT316052 Notch1 Regulation of Binding of Cd8a 1 0.01 0.86 0.15
60 INT316053 Notch1 Regulation of Binding of Cd4 1 0.02 0.86 0.15
61 INT74030 Adcyap1 Positive_regulation of Transcription of Penk 1 0.56 0.24 0.15
62 INT316050 Binding of Notch1 and Regulation of Binding of Cd8a 1 0.01 0.86 0.15
63 INT316051 Binding of Notch1 and Regulation of Binding of Cd4 1 0.02 0.86 0.15
64 INT190747 Adcyap1 Regulation of Positive_regulation of Prkaca 1 0.05 0 0.14
65 INT273041 Adcyap1 Regulation of Bax 1 0.21 1.69 0.13
66 INT315388 Binding of Adcyap1r1 and Adcyap1 1 0.02 0.5 0.12
67 INT190743 Adcyap1 Regulation of Gene_expression of Car2 1 0.10 0.06 0.12
68 INT72729 Adcyap1 Positive_regulation of Localization of Slc4a4 1 0.23 0 0.12
69 INT93478 Adcyap1 Regulation of Vip 1 0.31 0 0.1
70 INT297548 Neurod1 Regulation of Hes1 1 0.05 0.2 0.1
71 INT315383 Adcyap1 Regulation of Stat1 1 0.10 0.07 0.09
72 INT234222 PSEN1 Regulation of Gene_expression of NOTCH1 1 0.03 0 0.08
73 INT171400 Binding of Adcyap1 and Prkcg 1 0.01 0.24 0.08
74 INT190742 Adcyap1 Regulation of Gria2 1 0.00 0 0.08
75 INT110952 Adcyap1 Regulation of Localization of LH 1 0.22 0 0.07
76 INT189557 Binding of NOTCH1 and ROBO4 1 0.01 0.22 0.06
77 INT315399 Adcyap1 Positive_regulation of Binding of IFNA1 1 0.02 0 0.06
78 INT190750 Adcyap1 Regulation of Positive_regulation of Adcyap1r1 1 0.11 0 0.06
79 INT206675 Adcyap1 Positive_regulation of Gene_expression of Per1 1 0.05 0 0.05
80 INT171401 Binding of Adcyap1 and Npr1 1 0.02 0.23 0.04
81 INT349314 Binding of Notch1 and Notch3 1 0.11 0.67 0.04
82 INT190738 Adcyap1 Positive_regulation of Gene_expression of Gnb2l1 1 0.08 0 0.03
83 INT347165 Binding of NOTCH1 and PAX5 1 0.05 0.86 0.03
84 INT347163 NOTCH1 Positive_regulation of MSC 1 0.03 0.85 0.03
85 INT347164 NOTCH1 Negative_regulation of Gene_expression of EBF1 1 0.03 0.85 0.03
86 INT190748 Adcyap1 Regulation of Gene_expression of Gopc 1 0.05 0 0.03
87 INT258529 Binding of JAG1 and NOTCH1 3 0.06 2.44 0
88 INT258528 Binding of NOTCH1 and DLL1 2 0.07 1.6 0
89 INT291330 Binding of ENO1 and NOTCH1 1 0.03 1.33 0
90 INT193946 Binding of Notch1 and Positive_regulation of Psen1 1 0.03 0.06 0
91 INT264735 Binding of Hes1 and Mir199b 1 0.08 0.93 0
92 INT215349 Binding of VDAC1 and Tspo 1 0.00 0.63 0
93 INT264738 Mir199b Regulation of Gene_expression of Hes1 1 0.08 0.89 0
94 INT291329 Binding of NOTCH1 and CERS1 1 0.06 1.42 0
95 INT356083 Binding of App and Notch1 1 0.02 0.2 0
96 INT193949 Alph1 Positive_regulation of Notch1 1 0.01 0.08 0
97 INT191614 Adcyap1 Positive_regulation of Rtcd1 1 0.01 0.93 0
98 INT264736 Hes1 Regulation of Notch2 1 0.20 0.13 0
99 INT193950 Alph1 Positive_regulation of Positive_regulation of Notch1 1 0.01 0.07 0
100 INT322661 Binding of Tspo and Pbrm1 1 0.00 1.08 0
101 INT197316 Hes1 Regulation of Atoh1 1 0.01 0.14 0
102 INT321882 Binding of TSPO and Lm370 1 0.01 0.4 0
103 INT193948 Binding of Psen1 and Notch1 1 0.02 0 0
104 INT264727 Binding of Notch1 and Mir199b 1 0.00 0.86 0
105 INT197304 Ahr Regulation of Hes1 1 0.06 0.17 0
106 INT264731 Gene_expression of Hes1 Negative_regulation of Positive_regulation of Musd1 1 0.00 0.18 0
107 INT343161 ACSL4 Regulation of Gene_expression of TSPO 1 0.25 0.75 0
108 INT264728 Mir199b Regulation of Notch1 1 0.01 0.85 0
109 INT74023 Adcyap1 Regulation of Transcription of Penk 1 0.32 0.2 0
110 INT193147 CRAMP1L Regulation of TSPO 1 0.01 0.27 0
111 INT285770 Binding of NOTCH1 and Das 1 0.00 1.14 0
112 INT264726 Binding of Notch1 and Gtf3a 1 0.00 1.68 0
113 INT356084 Binding of Notch1 and Ncstn 1 0.01 0.07 0
114 INT264729 Mir199b Regulation of Hes1 1 0.05 0.25 0
115 INT285769 Das Regulation of NOTCH1 1 0.00 0.78 0
116 INT343156 Binding of TSPO and DBI 1 0.04 0.63 0
117 INT197310 Hes1 Regulation of Ascl1 1 0.01 0.14 0
118 INT193947 Notch1 Positive_regulation of Alph1 1 0.01 0.07 0
119 INT291333 Binding of CSHL1 and NOTCH1 1 0.05 1.16 0
120 INT264725 Binding of Hes1 and Notch1 1 0.03 0.84 0
121 INT264734 Mir199b Negative_regulation of Negative_regulation of Hes1 1 0.07 0.1 0
122 INT219502 TSPO Positive_regulation of Positive_regulation of Ppib 1 0.01 0 0
123 INT258564 Binding of NOTCH1 and Crlf2 1 0.27 0.67 0
124 INT264739 Mir199b Negative_regulation of Gene_expression of Hes1 1 0.07 0.82 0
125 INT264737 Hes1 Regulation of Shh 1 0.19 0.13 0
126 INT219424 Binding of AHR and TSPO 1 0.01 0 0
127 INT283711 Sox11 Regulation of 4930579C15Rik 1 0.28 0.74 0
128 INT264733 Hes1 Regulation of Mir199b 1 0.05 0.43 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of glial cell proliferation. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of glial cell proliferation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT54077 Gene_expression of Adcyap1 62 0.78 23.17 16.75
2 INT58896 Localization of Adcyap1 35 0.81 4.57 14.77
3 INT48259 Positive_regulation of Adcyap1 33 0.67 10.94 14.39
4 INT65965 Gene_expression of Adcyap1 52 0.78 22.53 13.14
5 INT18088 Binding of Tspo 26 0.48 9.12 10.2
6 INT424 Positive_regulation of TSPO 34 0.61 15.04 10.02
7 INT106199 Positive_regulation of Adcyap1 32 0.68 13.68 9.14
8 INT52116 Regulation of Adcyap1 20 0.53 6.1 8.14
9 INT39170 Gene_expression of TSPO 76 0.78 24.11 8.05
10 INT6335 Binding of TSPO 39 0.44 10.88 7.66
11 INT65964 Regulation of Adcyap1 13 0.45 10.1 7.54
12 INT14258 Regulation of TSPO 32 0.60 10.16 6.24
13 INT43224 Negative_regulation of Adcyap1 17 0.54 3.69 6.19
14 INT123726 Positive_regulation of Notch1 23 0.70 7.2 5.65
15 INT16051 Regulation of Tspo 6 0.45 2.81 4.95
16 INT29809 Gene_expression of Tspo 8 0.75 4.12 4.54
17 INT66048 Positive_regulation of Gene_expression of Adcyap1 5 0.49 8.21 4.52
18 INT7841 Gene_expression of Tspo 10 0.75 7.63 4.45
19 INT69217 Gene_expression of Notch1 20 0.78 7.8 4.41
20 INT6881 Binding of Tspo 12 0.46 5.03 4.38
21 INT106548 Localization of Adcyap1 14 0.80 5.05 4.33
22 INT138209 Positive_regulation of Localization of Adcyap1 2 0.41 2.07 4.08
23 INT115877 Negative_regulation of Adcyap1 14 0.59 5.31 3.74
24 INT59154 Binding of Adcyap1 12 0.48 4.16 3.71
25 INT122323 Positive_regulation of NOTCH1 36 0.70 35.63 3.7
26 INT84427 Positive_regulation of Gene_expression of TSPO 15 0.64 5.05 3.58
27 INT36716 Positive_regulation of Gene_expression of Tspo 4 0.68 3.48 3.49
28 INT58897 Regulation of Localization of Adcyap1 4 0.45 1.82 3.48
29 INT120823 Positive_regulation of Gene_expression of Adcyap1 10 0.68 6.71 3.22
30 INT25745 Regulation of Tspo 6 0.45 0.25 3.1
31 INT139872 Regulation of Notch1 14 0.45 7.69 2.82
32 INT119025 Gene_expression of NOTCH1 46 0.75 31.32 2.64
33 INT74131 Positive_regulation of Tspo 7 0.50 0.92 2.11
34 INT54076 Transcription of Adcyap1 4 0.67 1.65 1.98
35 INT77300 Negative_regulation of Positive_regulation of Adcyap1 3 0.35 0 1.88
36 INT14257 Localization of TSPO 9 0.73 1.48 1.87
37 INT140036 Positive_regulation of Gene_expression of Notch1 6 0.61 2 1.86
38 INT66047 Regulation of Gene_expression of Adcyap1 2 0.58 3.36 1.84
39 INT19576 Negative_regulation of Tspo 3 0.42 1.02 1.75
40 INT6391 Positive_regulation of Tspo 2 0.50 0.93 1.63
41 INT163381 Transcription of Notch1 2 0.69 0.41 1.52
42 INT59153 Positive_regulation of Binding of Adcyap1 3 0.43 0.56 1.37
43 INT130098 Negative_regulation of NOTCH1 11 0.42 5.45 1.33
44 INT110784 Protein_catabolism of Notch1 8 0.21 2.32 1.31
45 INT149295 Regulation of NOTCH1 10 0.13 4.26 1.22
46 INT110780 Localization of Notch1 2 0.06 0.47 1.19
47 INT149292 Localization of NOTCH1 7 0.54 6.11 1.14
48 INT123727 Negative_regulation of Notch1 6 0.21 1.22 1.11
49 INT106549 Binding of Adcyap1 3 0.35 1.83 1.08
50 INT284686 Positive_regulation of Gene_expression of Tspo 1 0.66 2.55 0.9
51 INT43221 Negative_regulation of Negative_regulation of Adcyap1 1 0.18 0 0.85
52 INT6806 Localization of Tspo 3 0.70 0 0.82
53 INT125782 Positive_regulation of Binding of Tspo 1 0.67 1.51 0.79
54 INT125781 Negative_regulation of Binding of Tspo 2 0.41 1.21 0.74
55 INT210014 Regulation of Binding of Adcyap1 1 0.38 0.25 0.73
56 INT210012 Regulation of Transcription of Adcyap1 1 0.44 0.48 0.7
57 INT69003 Negative_regulation of Binding of TSPO 4 0.03 2.78 0.69
58 INT140037 Positive_regulation of Positive_regulation of Notch1 2 0.22 1.34 0.69
59 INT210011 Negative_regulation of Gene_expression of Adcyap1 1 0.36 1.22 0.69
60 INT21342 Negative_regulation of Tspo 1 0.11 0 0.68
61 INT191341 Negative_regulation of Gene_expression of TSPO 3 0.34 1.66 0.64
62 INT163859 Negative_regulation of Gene_expression of Tspo 1 0.41 0.17 0.64
63 INT264709 Gene_expression of Hes1 24 0.76 7.04 0.63
64 INT73850 Transcription of TSPO 6 0.59 0.83 0.61
65 INT204138 Regulation of Gene_expression of TSPO 2 0.36 0.99 0.6
66 INT136920 Positive_regulation of Gene_expression of NOTCH1 12 0.49 8.25 0.59
67 INT120054 Regulation of Gene_expression of Tspo 2 0.44 0.97 0.59
68 INT137580 Negative_regulation of Gene_expression of Adcyap1 3 0.43 0.15 0.57
69 INT178718 Phosphorylation of TSPO 1 0.79 0.91 0.56
70 INT178717 Negative_regulation of Localization of TSPO 1 0.41 0.92 0.56
71 INT110782 Negative_regulation of Localization of Notch1 1 0.03 0.33 0.56
72 INT149294 Regulation of Localization of NOTCH1 1 0.10 0.9 0.55
73 INT110785 Positive_regulation of Protein_catabolism of Notch1 1 0.05 0.33 0.55
74 INT73849 Negative_regulation of TSPO 8 0.59 2.4 0.53
75 INT149297 Protein_catabolism of NOTCH1 2 0.15 0.87 0.51
76 INT68358 Regulation of Positive_regulation of Adcyap1 1 0.44 0 0.5
77 INT159678 Transcription of Tspo 1 0.53 0.64 0.49
78 INT205265 Regulation of Transcription of TSPO 1 0.21 0.13 0.49
79 INT203480 Negative_regulation of Transcription of Adcyap1 1 0.41 0.81 0.47
80 INT203479 Transcription of Adcyap1 1 0.67 0.81 0.47
81 INT158426 Binding of NOTCH1 10 0.36 7.95 0.45
82 INT115876 Regulation of Gene_expression of Adcyap1 1 0.38 0.47 0.44
83 INT61831 Regulation of Regulation of TSPO 1 0.03 0.16 0.43
84 INT135139 Regulation of Positive_regulation of Tspo 1 0.05 0.17 0.37
85 INT283698 Gene_expression of Sox11 1 0.68 4.6 0.33
86 INT146646 Protein_catabolism of TSPO 3 0.86 0.58 0.32
87 INT258685 Regulation of Gene_expression of Notch1 2 0.40 1.45 0.3
88 INT159677 Positive_regulation of Transcription of Tspo 1 0.46 0.33 0.27
89 INT190727 Negative_regulation of Positive_regulation of Adcyap1 1 0.27 0 0.25
90 INT69072 Positive_regulation of Negative_regulation of Adcyap1 1 0.50 0 0.25
91 INT316049 Regulation of Regulation of Notch1 1 0.03 0.92 0.23
92 INT130099 Negative_regulation of Positive_regulation of NOTCH1 4 0.43 2.56 0.21
93 INT193945 Binding of Notch1 7 0.15 1.28 0.19
94 INT130096 Positive_regulation of Positive_regulation of NOTCH1 2 0.50 1.15 0.18
95 INT264701 Negative_regulation of Gene_expression of Hes1 1 0.42 0.73 0.18
96 INT284590 Regulation of Localization of Adcyap1 1 0.07 0 0.17
97 INT190732 Regulation of Positive_regulation of Adcyap1 1 0.33 0 0.13
98 INT338718 Positive_regulation of Localization of NOTCH1 1 0.04 0.6 0.13
99 INT116635 Positive_regulation of Localization of Adcyap1 1 0.70 0 0.11
100 INT73848 Positive_regulation of Transcription of TSPO 3 0.42 0.58 0.1
101 INT273033 Regulation of Binding of Adcyap1 1 0.31 0.63 0.1
102 INT315377 Negative_regulation of Binding of Adcyap1 1 0.18 0.07 0.09
103 INT141999 Regulation of Gene_expression of NOTCH1 2 0.04 0.97 0.08
104 INT87511 Regulation of Regulation of Adcyap1 1 0.23 0.57 0.08
105 INT283695 Binding of Sox11 1 0.32 0.18 0.08
106 INT283696 Localization of Sox11 1 0.65 0.37 0.05
107 INT298336 Phosphorylation of Notch1 1 0.02 0.13 0.04
108 INT264717 Negative_regulation of Hes1 7 0.42 0.77 0.03
109 INT264704 Regulation of Hes1 4 0.44 1.03 0.03
110 INT350959 Transcription of NOTCH1 2 0.05 0.84 0.03
111 INT264702 Positive_regulation of Gene_expression of Hes1 1 0.68 1.39 0.03
112 INT264719 Regulation of Gene_expression of Hes1 2 0.28 0.12 0
113 INT264708 Transcription of Hes1 1 0.67 0.83 0
114 INT264724 Negative_regulation of Positive_regulation of Notch1 1 0.03 0.77 0
115 INT283699 Positive_regulation of Sox11 1 0.35 0.62 0
116 INT300174 Negative_regulation of Gene_expression of NOTCH1 1 0.04 0.53 0
117 INT264705 Binding of Hes1 1 0.35 0.07 0
118 INT234247 Negative_regulation of Protein_catabolism of NOTCH1 1 0.05 0 0
119 INT130094 Regulation of Positive_regulation of NOTCH1 1 0.45 0.52 0
120 INT264706 Positive_regulation of Hes1 1 0.40 0.14 0
121 INT180906 Negative_regulation of Positive_regulation of TSPO 1 0.50 0 0
122 INT264723 Negative_regulation of Gene_expression of Notch1 1 0.03 0.83 0
123 INT273836 Positive_regulation of Regulation of Notch1 1 0.15 0.05 0
124 INT274728 Regulation of Binding of TSPO 1 0.02 0 0
125 INT293972 Positive_regulation of Binding of TSPO 1 0.04 1.01 0
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