GO:0060315

From wiki-pain
Jump to: navigation, search
Name negative regulation of ryanodine-sensitive calcium-release channel activity
Categary Process
Go Slim No
Go Link GO:0060315
Unique Molecular Interactions 47
Total Molecular Interactions 84
Total Single Events 167
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of ryanodine-sensitive calcium-release channel activity. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of ryanodine-sensitive calcium-release channel activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT97013 Negative_regulation of Binding of CALM3 and OPRM1 1 0.40 0 1.05
2 INT97011 Binding of CALM3 and OPRM1 1 0.35 0 1.05
3 INT309735 Binding of CALM3 and TRPV4 1 0.14 0 0.75
4 INT241247 Binding of Pkd2 and Trpv4 1 0.54 1.22 0.52
5 INT261058 Binding of CALM3 and CHR 1 0.04 0.14 0.38
6 INT279705 CALM3 Regulation of TRPV4 2 0.08 0 0.33
7 INT126942 Binding of PKD2 and ZACN 1 0.00 1.38 0.28
8 INT261056 Binding of CALM3 and PLA2G6 1 0.09 0 0.27
9 INT261045 Negative_regulation of Binding of CALM3 and PLA2G6 1 0.10 0 0.27
10 INT261052 CALM3 Regulation of VIP 1 0.00 0.06 0.25
11 INT309729 CALM3 Regulation of TRPV1 1 0.04 0 0.22
12 INT7332 CALM3 Positive_regulation of ADCY1 1 0.46 0.13 0.21
13 INT126944 Binding of PKD2 and Pkd1 2 0.08 2.09 0.19
14 INT241250 Binding of Pkd2 and Trpc1 1 0.23 0.3 0.17
15 INT261055 Negative_regulation of Binding of CALM3 and CHR 1 0.04 0 0.14
16 INT309743 Binding of CA2 and CALM3 1 0.04 0 0.13
17 INT309747 CALM3 Regulation of TRPV5 1 0.03 0 0.13
18 INT309742 CALM3 Regulation of TRPV3 1 0.04 0 0.13
19 INT309733 CALM3 Regulation of TRPV6 1 0.01 0 0.13
20 INT241248 Binding of Pkd1 and Pkd2 3 0.22 1.52 0.1
21 INT352751 Pkd2 Regulation of Localization of Vegfa 1 0.11 0.47 0.1
22 INT352750 Pkd2 Positive_regulation of Vegfa 1 0.20 0.47 0.1
23 INT309725 Gene_expression of CALM3 Negative_regulation of Positive_regulation of TRPC6 1 0.07 0 0.1
24 INT241249 Pkd2 Regulation of Trpc1 1 0.21 0.14 0.09
25 INT286565 Pkd2 Positive_regulation of Positive_regulation of Pkd1 1 0.21 0.11 0.09
26 INT309738 CALM3 Positive_regulation of CA2 1 0.04 0 0.08
27 INT309737 Binding of CALM3 and Positive_regulation of CA2 1 0.04 0 0.08
28 INT241246 Pkd2 Negative_regulation of Gene_expression of Trpv4 1 0.48 0.47 0.07
29 INT275105 CALM3 Positive_regulation of Prkcg 1 0.00 0 0.06
30 INT309748 CALM3 Regulation of CA2 1 0.02 0 0.06
31 INT309732 CALM3 Positive_regulation of Gene_expression of TRPV4 1 0.14 0 0.06
32 INT309752 CALM3 Positive_regulation of Gene_expression of CA2 1 0.04 0 0.06
33 INT309730 Binding of CALM3 and TYRP1 1 0.01 0 0.05
34 INT261057 Binding of CALM3 and CHGA 1 0.04 0.14 0.04
35 INT261042 Binding of CALM3 and VIP 1 0.00 0.14 0.04
36 INT241253 Gene_expression of Trpv4 Positive_regulation of Gene_expression of Pkd2 1 0.52 0.29 0.03
37 INT241251 Pkd2 Negative_regulation of Gene_expression of Gopc 1 0.12 0.24 0.03
38 INT309745 Negative_regulation of Binding of CALM3 and TRPV4 1 0.12 0 0
39 INT261883 PKD2 Positive_regulation of Localization of Ca2 1 0.02 0.67 0
40 INT309746 CALM3 Positive_regulation of CAMK2G 1 0.02 0 0
41 INT309734 Binding of CALM3 and RPLP2 1 0.01 0 0
42 INT286570 Pkd2 Positive_regulation of Binding of Pkd1 1 0.21 0.73 0
43 INT286589 Binding of PKHD1 and Pkd2 1 0.09 0.52 0
44 INT286573 Pkd2 Regulation of Pkd1 1 0.12 0.25 0
45 INT286590 Binding of ID2 and Pkd2 1 0.13 0.13 0
46 INT309753 Binding of CALM3 and GOPC 1 0.04 0 0
47 INT309741 Binding of C2 and CALM3 1 0.03 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of ryanodine-sensitive calcium-release channel activity. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of ryanodine-sensitive calcium-release channel activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT97018 Binding of CALM3 7 0.43 0.13 5.82
2 INT7333 Localization of CALM3 4 0.72 0.4 1.55
3 INT97017 Regulation of Binding of CALM3 2 0.40 0 1.06
4 INT7338 Negative_regulation of CALM3 5 0.34 0.19 1
5 INT97014 Regulation of CALM3 1 0.55 0 0.97
6 INT97020 Negative_regulation of Regulation of CALM3 1 0.52 0 0.97
7 INT7335 Positive_regulation of CALM3 6 0.36 0.28 0.79
8 INT83375 Gene_expression of CALM3 3 0.58 1.57 0.78
9 INT137850 Gene_expression of PKD2 9 0.65 6.68 0.63
10 INT241235 Binding of Pkd2 11 0.48 2.43 0.55
11 INT241243 Gene_expression of Pkd2 30 0.77 9.05 0.53
12 INT241236 Negative_regulation of Pkd2 11 0.43 1.82 0.39
13 INT261086 Positive_regulation of Negative_regulation of CALM3 1 0.16 0 0.26
14 INT241238 Positive_regulation of Pkd2 5 0.46 1.44 0.24
15 INT241244 Localization of Pkd2 1 0.74 0.35 0.24
16 INT354535 Regulation of Negative_regulation of Pkd2 1 0.15 1.03 0.14
17 INT7334 Positive_regulation of Localization of CALM3 1 0.42 0.17 0.12
18 INT309767 Negative_regulation of Gene_expression of CALM3 1 0.13 0 0.1
19 INT309756 Positive_regulation of Gene_expression of CALM3 1 0.14 0 0.09
20 INT286583 Localization of PKD2 1 0.35 0.17 0.06
21 INT261879 Binding of PKD2 3 0.13 2.59 0.05
22 INT241241 Positive_regulation of Gene_expression of Pkd2 3 0.50 1.3 0.03
23 INT241239 Regulation of Pkd2 2 0.27 0.55 0
24 INT241245 Negative_regulation of PKD2 2 0.42 2.35 0
25 INT286546 Negative_regulation of Gene_expression of Pkd2 2 0.27 0.57 0
26 INT352724 Regulation of Gene_expression of Pkd2 1 0.10 0 0
27 INT352716 Negative_regulation of Regulation of Pkd2 1 0.15 0.08 0
28 INT232493 Negative_regulation of Positive_regulation of PKD2 1 0.23 0.61 0
29 INT261087 Negative_regulation of Positive_regulation of CALM3 1 0.12 0 0
30 INT261878 Negative_regulation of Binding of PKD2 1 0.14 0.6 0
31 INT309760 Negative_regulation of Binding of CALM3 1 0.13 0 0
32 INT232491 Positive_regulation of PKD2 1 0.27 0.56 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox