GO:0060317

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Name cardiac epithelial to mesenchymal transition
Categary Process
Go Slim No
Go Link GO:0060317
Unique Molecular Interactions 73
Total Molecular Interactions 96
Total Single Events 1016
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cardiac epithelial to mesenchymal transition. They are ordered first by their pain relevance and then by number of times they were reported for cardiac epithelial to mesenchymal transition. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT210783 Bmp2 Positive_regulation of Tnip1 1 0.40 0.53 0.94
2 INT210791 Bmp2 Positive_regulation of Net1 1 0.38 0.52 0.93
3 INT210799 Bmp2 Positive_regulation of B2m 1 0.35 0.52 0.92
4 INT161945 TGFB2 Positive_regulation of TGFBR1 1 0.08 0.99 0.76
5 INT161949 TGFB2 Positive_regulation of Gene_expression of Ngf 1 0.21 0.97 0.74
6 INT155254 Col4a4 Regulation of Rtn4 1 0.00 0 0.54
7 INT125086 LPA Positive_regulation of Rtn4 1 0.00 0.36 0.54
8 INT210793 Bmp2 Positive_regulation of Tsc22d3 1 0.32 0.26 0.46
9 INT72089 TGFB2 Positive_regulation of POMC 1 0.11 0 0.46
10 INT300609 Binding of Ctnnb1 and Wnt2 1 0.02 0.25 0.37
11 INT124380 Prodh2 Regulation of Wnt2 1 0.00 0.63 0.35
12 INT242162 Binding of Ccnd1 and Wnt2 1 0.10 0.23 0.34
13 INT242164 Wnt2 Positive_regulation of Localization of Apc 1 0.13 1.53 0.32
14 INT224687 Il1 Positive_regulation of Bmp2 1 0.00 0.3 0.31
15 INT69362 Binding of Pnoc and Rtn4 1 0.01 0 0.31
16 INT166165 Binding of TGFB3 and Bmp2 1 0.00 0 0.3
17 INT182817 EEF1A2 Positive_regulation of BMP2 1 0.26 1.62 0.28
18 INT325530 Positive_regulation of Gsk3b Negative_regulation of Gene_expression of Wnt2 1 0.03 0.63 0.28
19 INT141545 Binding of Bace1 and Rtn4 1 0.00 0.45 0.27
20 INT141550 Binding of Rtn4r and Rtn4 1 0.00 0.46 0.26
21 INT155158 Agtr2 Regulation of Rtn4 1 0.00 0.1 0.22
22 INT209851 TGFB2 Negative_regulation of Gene_expression of CD36 1 0.16 0.16 0.21
23 INT299435 Rspo3 Positive_regulation of Wnt2 1 0.06 0.35 0.19
24 INT314852 Binding of Cdkn2a and Tgfbr3 1 0.28 1.15 0.14
25 INT314859 Binding of Cdkn2b and Tgfbr3 1 0.33 1.16 0.14
26 INT242163 Wnt2 Positive_regulation of Regulation of Apc 1 0.13 0.71 0.13
27 INT326974 BMP2 Positive_regulation of Gene_expression of COL2A1 1 0.07 0.27 0.11
28 INT149178 IL4 Negative_regulation of Positive_regulation of TGFB2 1 0.15 0.29 0.1
29 INT352555 DKK1 Positive_regulation of Wnt2 1 0.01 0.25 0.1
30 INT238038 Binding of BMP2 and OPLL 1 0.20 2.45 0.09
31 INT297968 Positive_regulation of Binding of BMP2 and IL17C 1 0.21 0.26 0.08
32 INT297970 Binding of BMP2 and IL17C 1 0.15 0.26 0.08
33 INT329265 Binding of Ptk2 and Wnt2 1 0.05 1.04 0.07
34 INT295122 Bmp2 Regulation of Grxcr1 1 0.02 0.66 0.06
35 INT295120 Bmp2 Regulation of Transcription of Pou1f1 1 0.24 0.66 0.06
36 INT321891 Dkk1 Negative_regulation of Wnt2 1 0.12 0.94 0.05
37 INT210258 Wnt2 Regulation of Gene_expression of Tff3 1 0.03 0 0.05
38 INT173613 BMP2 Positive_regulation of INCENP 1 0.00 0.28 0.03
39 INT287233 PDLIM7 Positive_regulation of Gene_expression of BMP2 1 0.07 0.12 0.03
40 INT272528 THBS1 Positive_regulation of TGFB2 1 0.09 0.64 0.03
41 INT270938 Binding of Pick1 and Wnt2 1 0.00 0.18 0.03
42 INT314869 Binding of Gdf11 and Tgfbr3 1 0.29 0.14 0
43 INT343999 INCENP Positive_regulation of BMP2 1 0.01 0 0
44 INT203418 Enc1 Negative_regulation of Rtn4 1 0.08 0.58 0
45 INT278021 BMP2 Positive_regulation of Gene_expression of RUNX1T1 1 0.02 0.5 0
46 INT314871 Binding of Tgfbr3 and Atoh7 1 0.33 0.09 0
47 INT203406 Cap2 Negative_regulation of Rtn4 1 0.07 0.59 0
48 INT203410 Vsnl1 Negative_regulation of Rtn4 1 0.18 0.58 0
49 INT205451 Binding of BMP2 and Acvr2a 1 0.02 0.05 0
50 INT314862 Binding of Ltbp3 and Tgfb2 1 0.24 0.52 0
51 INT196023 Bmp2 Negative_regulation of Gene_expression of Bmp4 1 0.09 0.07 0
52 INT205410 Binding of BMP2 and BMPR2 1 0.07 0.05 0
53 INT344001 INCENP Positive_regulation of Gene_expression of BMP2 1 0.01 0 0
54 INT302323 Binding of SOST and Wnt2 1 0.02 0.26 0
55 INT242165 Wnt2 Positive_regulation of Gene_expression of Fzd1 1 0.15 0.26 0
56 INT196021 Bmp2 Positive_regulation of Gene_expression of Bmp4 1 0.09 0.08 0
57 INT295129 Proc Regulation of Bmp2 1 0.00 0.48 0
58 INT268398 Binding of LRP1 and Wnt2 1 0.01 0.36 0
59 INT335882 Dkk1 Negative_regulation of Wnt2 1 0.02 0.15 0
60 INT242166 Fzd1 Positive_regulation of Positive_regulation of Wnt2 1 0.13 0.24 0
61 INT203396 Mllt11 Negative_regulation of Rtn4 1 0.09 0.58 0
62 INT203399 Olfm1 Negative_regulation of Rtn4 1 0.09 0.58 0
63 INT321594 Bmp2 Regulation of Gene_expression of Lxn 1 0.42 1.71 0
64 INT242159 Wnt2 Positive_regulation of Localization of Casp3 1 0.05 0.25 0
65 INT314853 Binding of Cdc7 and Tgfbr3 1 0.24 0.09 0
66 INT325672 Wnt2 Positive_regulation of Gopc 1 0.01 0.58 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cardiac epithelial to mesenchymal transition. They are ordered first by their pain relevance and then by number of times they were reported in cardiac epithelial to mesenchymal transition. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5923 Negative_regulation of Rtn4 50 0.36 24.19 27.2
2 INT56239 Positive_regulation of Rtn4 20 0.26 14.05 18.8
3 INT5922 Gene_expression of Rtn4 27 0.48 12.7 17.86
4 INT53070 Regulation of Rtn4 15 0.22 9.35 13.77
5 INT75546 Transcription of Rtn4 1 0.06 2.87 5.03
6 INT124375 Gene_expression of Wnt2 67 0.56 38.03 4.67
7 INT156676 Gene_expression of Rtn4 14 0.65 5.78 3.16
8 INT85809 Gene_expression of BMP2 46 0.78 9.91 3.05
9 INT96423 Gene_expression of Bmp2 61 0.78 25.07 3.01
10 INT188047 Positive_regulation of Wnt2 51 0.58 31.41 2.94
11 INT129742 Regulation of Positive_regulation of Rtn4 2 0.05 2.51 2.33
12 INT130014 Positive_regulation of BMP2 11 0.66 5.34 1.42
13 INT235907 Regulation of Negative_regulation of Rtn4 1 0.07 2.93 1.42
14 INT242153 Negative_regulation of Wnt2 19 0.49 11.87 1.37
15 INT70619 Regulation of Bmp2 6 0.60 3.1 1.29
16 INT5920 Binding of Rtn4 6 0.36 0.66 1.21
17 INT96424 Transcription of Bmp2 6 0.69 6.34 1.11
18 INT160538 Binding of Bmp2 4 0.40 2.08 1.07
19 INT163963 Negative_regulation of Transcription of Rtn4 1 0.03 0.45 1.06
20 INT124374 Binding of Wnt2 21 0.31 10.16 0.99
21 INT81878 Gene_expression of TGFB2 3 0.42 2.02 0.97
22 INT114664 Binding of BMP2 12 0.37 6.54 0.91
23 INT242152 Transcription of Wnt2 8 0.57 5.22 0.88
24 INT104333 Negative_regulation of Positive_regulation of Rtn4 1 0.03 0.42 0.84
25 INT93737 Gene_expression of Tgfb2 2 0.03 1.16 0.77
26 INT93736 Positive_regulation of Gene_expression of Tgfb2 2 0.02 1.16 0.77
27 INT104457 Negative_regulation of Gene_expression of Rtn4 1 0.01 0.64 0.71
28 INT115297 Positive_regulation of TGFB2 4 0.29 1.91 0.65
29 INT124373 Positive_regulation of Gene_expression of Wnt2 14 0.42 8.28 0.6
30 INT238049 Positive_regulation of Gene_expression of BMP2 8 0.51 2.06 0.59
31 INT115292 Regulation of TGFB2 4 0.17 2.79 0.58
32 INT213503 Regulation of Wnt2 9 0.37 3.54 0.56
33 INT130047 Localization of TGFB2 3 0.16 3.65 0.53
34 INT85808 Localization of BMP2 7 0.77 1.94 0.51
35 INT145301 Regulation of Gene_expression of Bmp2 1 0.32 1.16 0.48
36 INT201524 Localization of Wnt2 14 0.62 9.24 0.46
37 INT188050 Regulation of Gene_expression of Wnt2 9 0.37 3.13 0.44
38 INT120086 Gene_expression of Bmp2 5 0.27 2.34 0.43
39 INT5921 Positive_regulation of Gene_expression of Rtn4 1 0.26 0.35 0.42
40 INT248931 Positive_regulation of Tgfb2 1 0.03 0 0.4
41 INT84945 Transcription of BMP2 5 0.61 1.8 0.36
42 INT196026 Positive_regulation of Gene_expression of Bmp2 14 0.69 3.19 0.35
43 INT242156 Positive_regulation of Transcription of Wnt2 2 0.42 0.23 0.34
44 INT242149 Negative_regulation of Transcription of Wnt2 2 0.35 1.8 0.33
45 INT242150 Positive_regulation of Positive_regulation of Wnt2 1 0.42 0.65 0.31
46 INT242154 Negative_regulation of Gene_expression of Wnt2 2 0.35 0.89 0.3
47 INT316692 Regulation of Localization of TGFB2 1 0.03 1.13 0.3
48 INT145305 Positive_regulation of Bmp2 12 0.69 8.65 0.24
49 INT109699 Regulation of BMP2 5 0.43 2.21 0.23
50 INT235908 Localization of Rtn4 1 0.08 0.25 0.23
51 INT352553 Negative_regulation of Binding of Wnt2 1 0.03 0.49 0.2
52 INT226977 Positive_regulation of Gene_expression of Rtn4 1 0.51 1.1 0.19
53 INT268392 Regulation of Positive_regulation of Wnt2 2 0.09 0.87 0.18
54 INT148064 Localization of Bmp2 2 0.29 0.14 0.17
55 INT106010 Positive_regulation of Bmp2 2 0.26 0.91 0.15
56 INT216038 Binding of Rtn4 1 0.40 0.8 0.13
57 INT242157 Regulation of Localization of Wnt2 3 0.37 1.08 0.11
58 INT254992 Negative_regulation of Gene_expression of BMP2 3 0.34 0.56 0.11
59 INT238044 Positive_regulation of Transcription of BMP2 2 0.43 0.83 0.11
60 INT326976 Regulation of Localization of BMP2 1 0.59 0.08 0.1
61 INT196035 Localization of Bmp2 3 0.63 0.23 0.09
62 INT278036 Negative_regulation of BMP2 2 0.34 0.64 0.09
63 INT114663 Regulation of Binding of BMP2 1 0.38 0.19 0.09
64 INT163072 Regulation of Binding of Bmp2 1 0.30 0.52 0.08
65 INT343551 Positive_regulation of Localization of TGFB2 1 0.10 1.48 0.08
66 INT251229 Negative_regulation of Tgfb2 1 0.34 0.06 0.07
67 INT216029 Positive_regulation of Binding of Rtn4 1 0.38 0.33 0.06
68 INT201777 Phosphorylation of Wnt2 2 0.03 1.31 0.05
69 INT196025 Negative_regulation of Bmp2 2 0.34 0.14 0.05
70 INT229753 Positive_regulation of Gene_expression of Bmp2 2 0.11 1.22 0.04
71 INT287236 Positive_regulation of Positive_regulation of BMP2 1 0.29 0.08 0.04
72 INT242148 Negative_regulation of Negative_regulation of Wnt2 1 0.35 1.06 0.04
73 INT258058 Phosphorylation of TGFB2 1 0.08 0.89 0.04
74 INT325493 Positive_regulation of Binding of Wnt2 1 0.08 0.5 0.04
75 INT216031 Positive_regulation of Rtn4 1 0.57 0.79 0.03
76 INT242158 Protein_catabolism of Wnt2 1 0.54 0.25 0.03
77 INT242151 Negative_regulation of Protein_catabolism of Wnt2 1 0.36 0.31 0.03
78 INT189593 Regulation of Gene_expression of BMP2 2 0.33 0.8 0
79 INT145300 Positive_regulation of Positive_regulation of Bmp2 2 0.34 1.03 0
80 INT196031 Binding of Bmp2 1 0.16 0 0
81 INT314821 Binding of Tgfb2 1 0.36 0.51 0
82 INT322563 Negative_regulation of Positive_regulation of Wnt2 1 0.06 1.76 0
83 INT278735 Negative_regulation of Gene_expression of Bmp2 1 0.43 0.06 0
84 INT159211 Positive_regulation of Gene_expression of TGFB2 1 0.06 0 0
85 INT278737 Positive_regulation of Transcription of Bmp2 1 0.47 1.4 0
86 INT120087 Negative_regulation of Gene_expression of Bmp2 1 0.11 0.14 0
87 INT351109 Transcription of TGFB2 1 0.24 0.94 0
88 INT314839 Binding of Tgfbr3 1 0.42 0.09 0
89 INT314836 Gene_expression of Tgfbr3 1 0.59 0.09 0
90 INT278040 Negative_regulation of Localization of BMP2 1 0.32 0.32 0
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