GO:0060325

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Name face morphogenesis
Categary Process
Go Slim No
Go Link GO:0060325
Unique Molecular Interactions 406
Total Molecular Interactions 494
Total Single Events 3597
Pain Genes Associated 28

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for face morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported for face morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
2 INT192161 Mmp14 Positive_regulation of Mmp2 2 0.19 1.23 1.81
3 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76
4 INT102160 Binding of Mmp2 and Mmp9 3 0.28 2.87 1.75
5 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 3 0.38 4.29 1.71
6 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63
7 INT157460 CX3CL1 Regulation of Gene_expression of COL1A1 1 0.11 1.57 1.37
8 INT187174 RPS3AP9 Negative_regulation of MMP2 1 0.00 0.9 1.22
9 INT75483 Binding of SGCG and TGFB1 1 0.52 2.27 1.19
10 INT142077 TGFB1 Negative_regulation of Binding of IDO1 1 0.15 2.07 1.19
11 INT91394 Negative_regulation of MMP2 Positive_regulation of CALCA 1 0.25 0.15 1.15
12 INT91395 MMP2 Positive_regulation of CALCA 1 0.36 0.17 1.07
13 INT120313 Gnrhr Negative_regulation of Mmp2 1 0.03 0.85 1.07
14 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
15 INT129206 RYBP Positive_regulation of Gene_expression of TGFB1 1 0.00 1.04 0.95
16 INT222979 Negative_regulation of Binding of COL1A1 and FN1 1 0.01 1.64 0.93
17 INT222978 Binding of COL1A1 and FN1 1 0.01 1.64 0.92
18 INT254242 TNF Positive_regulation of Gene_expression of DKK1 1 0.14 1.24 0.91
19 INT222988 TNF Positive_regulation of Protein_catabolism of COL1A1 1 0.01 1.66 0.9
20 INT169477 TGFB3 Positive_regulation of Spink3 1 0.02 1.83 0.89
21 INT109103 MMP2 Positive_regulation of INS 1 0.33 1.07 0.89
22 INT196523 Binding of MMP2 and TIMP1 3 0.43 1.94 0.85
23 INT190165 MMP12 Positive_regulation of MMP2 1 0.13 0.72 0.85
24 INT222985 CP Positive_regulation of Positive_regulation of TGFB1 1 0.00 1.57 0.85
25 INT192158 Binding of Mmp2 and Mmp9 1 0.21 0.94 0.83
26 INT106808 RECK Negative_regulation of MMP2 1 0.40 0.5 0.83
27 INT278690 LEF1 Negative_regulation of Gene_expression of IK 1 0.00 0.66 0.83
28 INT135781 Cyp3a23/3a1 Positive_regulation of Positive_regulation of Col1a1 1 0.01 0.78 0.8
29 INT196525 Binding of MMP2 and MMP9 2 0.32 2.49 0.78
30 INT278697 LEF1 Negative_regulation of STAT6 1 0.00 0.44 0.78
31 INT102161 Binding of TNF and Mmp2 1 0.10 0.88 0.78
32 INT161485 Il1b Regulation of Gene_expression of TGFB1 1 0.47 1.21 0.77
33 INT161483 Slc7a12 Regulation of Gene_expression of TGFB1 1 0.14 1.21 0.77
34 INT102159 Binding of Adam17 and Mmp2 1 0.18 0.87 0.77
35 INT161482 Il1b Negative_regulation of TGFB1 1 0.45 1.17 0.76
36 INT26497 TNF Positive_regulation of Gene_expression of MMP2 1 0.44 1.5 0.75
37 INT161484 Binding of TGFB1 and Il1b 1 0.37 1.16 0.73
38 INT207540 Tfap2a Regulation of Oprm1 1 0.13 0.06 0.7
39 INT135207 Gmeb1 Regulation of Gene_expression of Tfap2a 1 0.07 0.48 0.69
40 INT135206 Ighen Regulation of Gene_expression of Tfap2a 1 0.06 0.48 0.69
41 INT135202 Tfap2a Regulation of Gene_expression of Ighen 1 0.06 0.48 0.69
42 INT135213 Tfap2a Regulation of Gene_expression of Nfkb1 1 0.02 0.48 0.69
43 INT135211 Nfkb1 Regulation of Gene_expression of Tfap2a 1 0.02 0.48 0.69
44 INT135204 Tfap2a Regulation of Gene_expression of Gmeb1 1 0.10 0.48 0.69
45 INT263049 Positive_regulation of Binding of Mmp2 and Mmp9 1 0.35 0.83 0.69
46 INT302642 Binding of ARSA and TGFB1 1 0.05 0.28 0.68
47 INT207543 Tfap2a Regulation of Qsox1 1 0.04 0.06 0.67
48 INT354913 VDR Positive_regulation of TGFB1 1 0.05 1.33 0.67
49 INT152299 Mmp2 Negative_regulation of Tsc22d1 1 0.16 0.16 0.66
50 INT152297 Mmp2 Negative_regulation of Mmp9 1 0.39 0.16 0.65
51 INT99602 ZNF398 Negative_regulation of MMP2 1 0.14 0.85 0.63
52 INT314051 THL Negative_regulation of Localization of Mmp2 1 0.14 1.1 0.62
53 INT95431 Il1a Regulation of Mmp2 1 0.48 0.25 0.61
54 INT137017 Tgfb1 Positive_regulation of Gene_expression of Acta2 1 0.00 0.84 0.61
55 INT95433 Mmp3 Regulation of Mmp2 1 0.17 0.24 0.6
56 INT316831 CCL5 Positive_regulation of Gene_expression of MMP2 1 0.02 0.51 0.59
57 INT342624 VEGFA Negative_regulation of Mmp2 1 0.09 1.54 0.58
58 INT342619 Mmp2 Negative_regulation of Timp2 1 0.42 1.48 0.57
59 INT56088 TGFB1 Positive_regulation of Transcription of SERPINE1 1 0.46 0.83 0.57
60 INT345302 MMP15 Positive_regulation of MMP2 1 0.06 1.17 0.57
61 INT175627 TIMP1 Positive_regulation of MMP2 1 0.03 0.71 0.56
62 INT302645 ARSA Positive_regulation of Gene_expression of TGFB1 1 0.08 0.28 0.55
63 INT173553 TIMP1 Negative_regulation of MMP2 1 0.05 0 0.55
64 INT89144 TGFB1 Regulation of Gene_expression of Tcstv1 1 0.00 0.53 0.53
65 INT314043 THL Negative_regulation of Mmp2 1 0.22 2.11 0.53
66 INT150790 ZNF398 Positive_regulation of Localization of MMP2 1 0.04 0.51 0.53
67 INT92918 Atp6v0a2 Negative_regulation of Gene_expression of Tgfb1 1 0.01 0.83 0.52
68 INT192159 Mmp14 Regulation of Protein_catabolism of Col1a1 1 0.02 1.01 0.52
69 INT196521 Binding of MMP2 and TIMP2 1 0.30 0.68 0.52
70 INT150785 THBS1 Negative_regulation of MMP2 1 0.10 0.5 0.52
71 INT150792 THBS3 Negative_regulation of MMP2 1 0.11 0.49 0.51
72 INT196527 Positive_regulation of Binding of MMP1 and MMP2 1 0.44 0.74 0.51
73 INT196520 Binding of MMP1 and MMP2 1 0.33 0.74 0.51
74 INT150921 ZNF398 Negative_regulation of Gene_expression of Mmp2 1 0.00 0.46 0.5
75 INT230532 LILRB1 Positive_regulation of Gene_expression of Mmp2 1 0.14 1.04 0.5
76 INT244028 Positive_regulation of Binding of Cacnb3 and Tfap2a 1 0.01 0.24 0.49
77 INT244037 Positive_regulation of Binding of Prkaca and Tfap2a 1 0.01 0.24 0.49
78 INT89145 TGFB1 Positive_regulation of Tcstv1 1 0.00 0.49 0.49
79 INT244000 Positive_regulation of Binding of Tfap2a and Dnm1 1 0.04 0.24 0.49
80 INT244035 Binding of Prkaca and Tfap2a 1 0.01 0.24 0.49
81 INT302643 ARSA Positive_regulation of Localization of TGFB1 1 0.08 0.12 0.49
82 INT243997 Binding of Tfap2a and Dnm1 1 0.03 0.24 0.49
83 INT244060 Binding of Cacnb3 and Tfap2a 1 0.00 0.24 0.49
84 INT173597 Negative_regulation of Binding of MMP2 and Mmp13 1 0.14 0.83 0.48
85 INT173595 Binding of MMP2 and Mmp13 1 0.12 0.83 0.48
86 INT314053 VEGFA Positive_regulation of Gene_expression of Mmp2 1 0.02 0.2 0.47
87 INT138152 IL6 Positive_regulation of Transcription of Mmp2 1 0.00 0.23 0.46
88 INT138154 IL1B Positive_regulation of Transcription of Mmp2 1 0.04 0.23 0.46
89 INT138149 Tgfb1 Regulation of Mmp2 1 0.00 0.23 0.46
90 INT345304 MMP14 Positive_regulation of MMP2 1 0.08 0.2 0.45
91 INT169478 TGFB3 Positive_regulation of Tgfa 1 0.01 0.9 0.44
92 INT314050 THL Negative_regulation of Transcription of Mmp2 1 0.16 0.81 0.44
93 INT169466 TGFB3 Positive_regulation of HRAS 1 0.03 0.89 0.43
94 INT169465 TGFB3 Positive_regulation of MTG1 1 0.03 0.89 0.43
95 INT196348 PTGER2 Negative_regulation of Negative_regulation of MMP2 1 0.01 0.29 0.43
96 INT314042 THL Negative_regulation of Gene_expression of Mmp2 1 0.19 2.97 0.42
97 INT75488 Binding of TGFB1 and Tgfbr1 1 0.23 0.78 0.41
98 INT75487 Binding of TGFB1 and Tgfbr2 1 0.31 0.83 0.41
99 INT336340 Glp2r Positive_regulation of Gene_expression of TGFB1 1 0.14 0.67 0.39
100 INT94853 TGFB1 Positive_regulation of Gene_expression of COL7A1 3 0.06 0.57 0.38
101 INT179851 Il11 Positive_regulation of Mmp2 1 0.04 0 0.38
102 INT342622 Binding of MMP14 and Mmp2 1 0.39 1.15 0.37
103 INT185804 MMP2 Positive_regulation of SPP1 1 0.15 0.88 0.37
104 INT342617 Binding of Col18a1 and Mmp2 1 0.11 1.15 0.37
105 INT185798 SPP1 Positive_regulation of Gene_expression of MMP2 1 0.26 0.87 0.37
106 INT168202 Msx1 Negative_regulation of Gene_expression of Mc1r 1 0.21 0.49 0.35
107 INT137018 Tgfb1 Positive_regulation of Pscs 1 0.01 0.43 0.34
108 INT301054 Tfap2a Regulation of Gene_expression of Faslg 1 0.00 1.23 0.34
109 INT137013 Tgfb1 Positive_regulation of Gene_expression of Pscs 1 0.01 0.43 0.34
110 INT225119 Foxm1 Regulation of Localization of TGFB1 1 0.01 0.63 0.34
111 INT333457 Binding of PPARA and TGFB1 1 0.04 0 0.34
112 INT149896 Ihh Regulation of Gene_expression of Col1a1 1 0.06 0.89 0.33
113 INT56089 TGFB1 Regulation of SERPINE1 1 0.41 0.41 0.33
114 INT99603 ZNF398 Regulation of Transcription of MMP2 1 0.15 0.44 0.33
115 INT99598 ZNF398 Negative_regulation of Gene_expression of MMP2 1 0.10 0.44 0.33
116 INT299549 Binding of TGFB1 and Egf 1 0.02 0.32 0.32
117 INT340615 COL4A4 Regulation of MMP2 1 0.11 0.95 0.32
118 INT303446 Timp1 Negative_regulation of Mmp2 1 0.19 0.33 0.31
119 INT326090 Binding of Erbb2 and Mmp2 1 0.09 1.39 0.31
120 INT146893 TNF Negative_regulation of Dkk1 1 0.01 1.27 0.3
121 INT166165 Binding of TGFB3 and Bmp2 1 0.00 0 0.3
122 INT99601 ZNF398 Negative_regulation of Transcription of MMP2 1 0.10 0.41 0.3
123 INT200640 Agtr2 Positive_regulation of Gene_expression of TGFB1 1 0.03 1.35 0.29
124 INT200639 Ace Positive_regulation of Gene_expression of TGFB1 1 0.06 1.36 0.29
125 INT200631 AGT Positive_regulation of Gene_expression of TGFB1 1 0.06 1.36 0.29
126 INT75056 Binding of MC1R and Msx1 1 0.00 0.17 0.29
127 INT300552 Napa Positive_regulation of Gene_expression of TGFB1 1 0.01 0.88 0.29
128 INT137033 Tgfb1 Positive_regulation of Gene_expression of Col1a1 1 0.01 0.42 0.28
129 INT225101 TGFB1 Positive_regulation of Localization of COL1A1 1 0.03 0.59 0.28
130 INT137014 Positive_regulation of Pscs Positive_regulation of Gene_expression of Col1a1 1 0.01 0.42 0.28
131 INT225100 TGFB1 Positive_regulation of Gene_expression of COL1A1 1 0.04 0.59 0.28
132 INT137012 Pscs Positive_regulation of Gene_expression of Col1a1 1 0.01 0.42 0.28
133 INT328222 Mmp2 Regulation of Positive_regulation of Mmp13 1 0.05 0.69 0.28
134 INT137032 Il6 Positive_regulation of Localization of Tgfb1 1 0.04 0.51 0.27
135 INT139094 Csf2 Regulation of Tgfb1 1 0.42 0.58 0.26
136 INT148223 CXCL14 Regulation of Localization of Mmp2 1 0.01 0.71 0.26
137 INT271450 Thy1 Regulation of TGFB1 1 0.00 0.62 0.25
138 INT244687 Mmp14 Positive_regulation of Mmp2 1 0.23 0.48 0.25
139 INT222981 TGFB1 Positive_regulation of Gene_expression of MMRN1 1 0.09 1.62 0.25
140 INT271446 Thy1 Regulation of Col1a1 1 0.05 0.61 0.25
141 INT168203 Binding of Mc1r and Msx1 1 0.19 0.64 0.25
142 INT258521 EGFR Positive_regulation of MMP2 1 0.39 0.91 0.24
143 INT178076 EDN1 Positive_regulation of MMP2 1 0.04 0.88 0.24
144 INT225098 ZNF630 Regulation of Localization of TGFB1 1 0.01 0.44 0.24
145 INT225105 ZNF630 Regulation of TGFB1 1 0.01 0.44 0.24
146 INT252784 ROS1 Positive_regulation of Gene_expression of COL1A1 1 0.05 1.86 0.24
147 INT225118 Foxm1 Positive_regulation of Gene_expression of MMP2 1 0.01 0.34 0.23
148 INT9720 Binding of TGFB1 and Egf 1 0.01 0 0.23
149 INT168710 Ifng Regulation of TGFB1 1 0.00 0.3 0.23
150 INT163403 VEGFA Positive_regulation of MMP2 1 0.52 0.13 0.23
151 INT89475 TGFB1 Positive_regulation of Gene_expression of PTHLH 3 0.61 3.64 0.21
152 INT316810 Sparc Regulation of Col1a1 1 0.13 0.48 0.21
153 INT346458 ROS1 Regulation of Localization of TGFB1 1 0.00 1.71 0.21
154 INT114905 TGFB1 Positive_regulation of Transcription of COL7A1 1 0.02 0.08 0.21
155 INT75057 Binding of POMC and Msx1 2 0.39 0.6 0.2
156 INT205057 MMP3 Negative_regulation of MMP2 1 0.35 3.02 0.2
157 INT225099 ZNF630 Positive_regulation of Gene_expression of COL1A1 1 0.00 0.17 0.2
158 INT14869 Binding of EGF and TGFB3 1 0.14 0.69 0.19
159 INT153457 Tgfb1 Positive_regulation of Gene_expression of Ctgf 1 0.13 1.15 0.19
160 INT350718 Mir106b Regulation of TGFB1 1 0.00 0.42 0.18
161 INT350603 MIR25 Regulation of TGFB1 1 0.01 0.42 0.18
162 INT271451 TGFB1 Regulation of Serpine1 1 0.00 0.68 0.18
163 INT306425 Positive_regulation of Binding of TBX1 and VCF 1 0.02 1.15 0.18
164 INT306426 Binding of TBX1 and VCF 1 0.01 1.09 0.17
165 INT304279 ETS1 Positive_regulation of MMP2 1 0.05 1.83 0.17
166 INT185810 Binding of MMP2 and SPP1 1 0.14 0.34 0.17
167 INT304282 ETS1 Positive_regulation of Gene_expression of MMP2 1 0.05 1.83 0.17
168 INT296037 TGFB1 Positive_regulation of IL17A 1 0.02 0 0.17
169 INT220531 Atf3 Negative_regulation of Gene_expression of Mmp2 1 0.02 1.09 0.16
170 INT160083 TGFB1 Positive_regulation of Gene_expression of L1CAM 1 0.16 1.53 0.16
171 INT301121 Tgm7 Regulation of Gene_expression of Mmp2 1 0.52 2.53 0.16
172 INT85274 SGCG Positive_regulation of Mmp2 1 0.09 0.46 0.16
173 INT220515 Il10 Negative_regulation of Gene_expression of Mmp2 1 0.01 1.1 0.16
174 INT245314 Binding of HYAL1 and MMP2 1 0.16 0.29 0.15
175 INT250908 Binding of Mmp2 and Tsp1 1 0.04 0.09 0.15
176 INT97547 KITLG Negative_regulation of Msx1 1 0.00 0.08 0.15
177 INT245312 Negative_regulation of Binding of HYAL1 and MMP2 1 0.19 0.29 0.15
178 INT97542 Pomc Negative_regulation of Msx1 1 0.13 0.07 0.15
179 INT250906 Binding of Mmp2 and Thbs2 1 0.06 0.09 0.15
180 INT234801 RAB3GAP1 Regulation of RAB3A 1 0.08 1.64 0.15
181 INT350713 MIR219-1 Negative_regulation of Pdgfra 1 0.00 0.4 0.15
182 INT97545 Gtf3a Negative_regulation of Msx1 1 0.02 0.08 0.15
183 INT34484 FPR1 Positive_regulation of Localization of MMP2 1 0.36 0.15 0.15
184 INT195443 MMP2 Positive_regulation of Protein_catabolism of Mmp9 1 0.15 0.95 0.14
185 INT314039 THL Negative_regulation of Binding of Mmp2 1 0.16 1.62 0.14
186 INT299550 TGFB1 Negative_regulation of Glul 1 0.01 0.34 0.14
187 INT252902 PTTG1 Regulation of MMP2 1 0.01 1.5 0.14
188 INT250911 Thbs2 Regulation of Mmp2 1 0.05 0.3 0.13
189 INT296031 Negative_regulation of TGFB1 Regulation of IL10 1 0.01 1.01 0.13
190 INT296027 TGFB1 Regulation of TH1L 1 0.02 1 0.13
191 INT290443 Gene_expression of TIMP2 Negative_regulation of MMP2 1 0.06 1.56 0.13
192 INT157602 Binding of COL1A1 and COL3A1 1 0.04 0 0.13
193 INT299547 Negative_regulation of Binding of TGFB1 and Egf 1 0.02 0.1 0.13
194 INT296080 TGFB1 Regulation of Hand2 1 0.01 1 0.12
195 INT163404 Negative_regulation of VEGFA Positive_regulation of MMP2 1 0.48 0.07 0.12
196 INT214150 Binding of Mc3r and Msx1 1 0.03 0.5 0.12
197 INT331612 ETV4 Positive_regulation of Gene_expression of TGFB1 1 0.00 1.32 0.12
198 INT343472 Epo Positive_regulation of Gene_expression of Mmp2 1 0.15 0.62 0.12
199 INT296028 TGFB1 Regulation of IL10 1 0.01 1 0.12
200 INT316813 Sparc Negative_regulation of Gene_expression of Col1a1 1 0.13 0.67 0.12

Single Events

The table below shows the top 100 pain related interactions that have been reported for face morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported in face morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18
2 INT26500 Gene_expression of MMP2 201 0.78 110.57 46.9
3 INT29503 Gene_expression of Mmp2 95 0.77 56.92 31.68
4 INT55737 Positive_regulation of MMP2 101 0.68 59.11 27.71
5 INT86295 Gene_expression of Mmp2 114 0.76 73.68 24.25
6 INT34487 Localization of MMP2 56 0.81 31.41 23.61
7 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23
8 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2
9 INT74682 Positive_regulation of Mmp2 72 0.69 40.46 21.73
10 INT34488 Negative_regulation of MMP2 85 0.59 41.98 21.72
11 INT50814 Positive_regulation of Mmp2 72 0.68 51.37 20.42
12 INT12081 Localization of TGFB1 64 0.81 35.4 17.47
13 INT26501 Positive_regulation of Gene_expression of MMP2 51 0.67 39 15.16
14 INT19963 Gene_expression of COL1A1 118 0.59 42.11 15.15
15 INT36336 Gene_expression of Tgfb1 41 0.77 21.82 14.53
16 INT129883 Gene_expression of Dkk1 56 0.77 45.42 12.52
17 INT86291 Negative_regulation of Mmp2 33 0.57 20.38 10.76
18 INT74681 Positive_regulation of Gene_expression of Mmp2 23 0.55 15.58 10.74
19 INT34485 Negative_regulation of Localization of MMP2 17 0.50 9.96 10.49
20 INT26502 Negative_regulation of Gene_expression of MMP2 39 0.58 21.45 9.42
21 INT111903 Regulation of Mmp2 9 0.61 3.95 7.98
22 INT111398 Localization of Mmp2 37 0.76 23.78 7.17
23 INT67568 Positive_regulation of Localization of MMP2 14 0.31 8.58 6.79
24 INT108628 Regulation of MMP2 27 0.60 14.85 6.06
25 INT123551 Regulation of Mmp2 17 0.57 11.6 6
26 INT19086 Negative_regulation of COL1A1 32 0.38 16.77 5.98
27 INT87468 Negative_regulation of Mmp2 24 0.57 10.79 5.55
28 INT90202 Protein_catabolism of MMP2 15 0.94 7.47 5.41
29 INT89104 Binding of TGFB1 29 0.44 13.67 5.12
30 INT90374 Positive_regulation of Positive_regulation of MMP2 14 0.50 10.12 5.08
31 INT69215 Gene_expression of Col1a1 38 0.68 17.39 4.77
32 INT29502 Localization of Mmp2 18 0.79 3.49 4.64
33 INT19965 Positive_regulation of COL1A1 23 0.45 14.49 4.38
34 INT89103 Regulation of Gene_expression of TGFB1 15 0.56 8.11 4.37
35 INT111156 Negative_regulation of Dkk1 21 0.58 20.08 4.27
36 INT36335 Localization of Tgfb1 19 0.79 7.06 4.17
37 INT86293 Positive_regulation of Gene_expression of Mmp2 21 0.64 11.69 3.79
38 INT12083 Regulation of TGFB1 22 0.53 15.4 3.6
39 INT51848 Transcription of TGFB1 17 0.69 9.57 3.53
40 INT56300 Negative_regulation of Gene_expression of TGFB1 13 0.41 4.87 3.5
41 INT81229 Binding of COL1A1 24 0.35 12.07 3.3
42 INT69216 Positive_regulation of Tgfb1 14 0.49 5.84 3.29
43 INT85147 Positive_regulation of Gene_expression of Tgfb1 12 0.46 7.29 3.24
44 INT85149 Negative_regulation of Gene_expression of Tgfb1 11 0.42 4.73 3.19
45 INT67719 Positive_regulation of Col1a1 21 0.44 8.87 3.12
46 INT138141 Transcription of Mmp2 10 0.64 6.52 2.99
47 INT112667 Negative_regulation of Tgfb1 9 0.58 2.72 2.97
48 INT14872 Gene_expression of TGFB3 15 0.55 12.45 2.96
49 INT9130 Negative_regulation of TGFB1 16 0.41 12.21 2.92
50 INT106468 Regulation of Gene_expression of MMP2 11 0.50 3.53 2.77
51 INT111153 Positive_regulation of Dkk1 13 0.68 10.56 2.58
52 INT68091 Localization of COL1A1 19 0.66 9.13 2.56
53 INT8890 Transcription of Col1a1 10 0.63 4.02 2.48
54 INT103603 Negative_regulation of Gene_expression of Mmp2 16 0.51 12.29 2.47
55 INT79261 Positive_regulation of Gene_expression of COL1A1 24 0.36 7.49 2.45
56 INT32920 Gene_expression of Msx1 19 0.71 4.24 2.42
57 INT188255 Gene_expression of DKK1 19 0.60 12.69 2.39
58 INT97152 Protein_catabolism of COL1A1 11 0.74 8.03 2.3
59 INT55736 Transcription of MMP2 11 0.68 5.78 2.28
60 INT126513 Gene_expression of Col1a1 23 0.75 10.92 2.18
61 INT180923 Negative_regulation of Localization of Mmp2 6 0.46 7.84 2.17
62 INT263046 Negative_regulation of Gene_expression of Mmp2 7 0.34 5.98 2.09
63 INT12086 Regulation of Localization of TGFB1 4 0.43 1.65 2.09
64 INT185829 Negative_regulation of Positive_regulation of MMP2 7 0.40 4.93 2.02
65 INT113717 Negative_regulation of Gene_expression of COL1A1 21 0.41 6.14 2.01
66 INT46332 Binding of Mmp2 10 0.34 5.63 2
67 INT120857 Localization of Col1a1 10 0.71 2.33 1.93
68 INT74824 Positive_regulation of Transcription of TGFB1 6 0.67 2.58 1.84
69 INT96116 Transcription of COL1A1 10 0.44 4.57 1.81
70 INT91396 Positive_regulation of Negative_regulation of MMP2 3 0.33 0.97 1.8
71 INT139475 Negative_regulation of DKK1 14 0.52 9.2 1.76
72 INT152292 Regulation of Gene_expression of Mmp2 6 0.61 3.46 1.76
73 INT47889 Binding of MMP2 9 0.41 6.37 1.68
74 INT86712 Regulation of Gene_expression of Tgfb1 2 0.15 2.03 1.65
75 INT86294 Regulation of Gene_expression of Mmp2 3 0.60 1.12 1.62
76 INT133443 Transcription of Mmp2 8 0.69 2.48 1.61
77 INT344978 Negative_regulation of Gene_expression of Dkk1 1 0.58 4.38 1.59
78 INT278715 Gene_expression of LEF1 10 0.33 5.43 1.54
79 INT34486 Regulation of Localization of MMP2 4 0.35 2.19 1.54
80 INT153201 Negative_regulation of Gene_expression of Col1a1 7 0.38 6.37 1.52
81 INT110992 Positive_regulation of Positive_regulation of TGFB1 4 0.50 3.01 1.51
82 INT142719 Binding of Col1a1 7 0.34 5.83 1.47
83 INT278727 Negative_regulation of Gene_expression of LEF1 3 0.11 1.59 1.47
84 INT207521 Gene_expression of Tfap2a 7 0.48 1.89 1.45
85 INT321889 Negative_regulation of Dkk1 2 0.38 5.7 1.42
86 INT12085 Positive_regulation of Localization of TGFB1 7 0.42 4.9 1.4
87 INT86292 Positive_regulation of Positive_regulation of Mmp2 4 0.46 3.09 1.4
88 INT109105 Positive_regulation of Protein_catabolism of MMP2 3 0.46 1.98 1.38
89 INT317979 Positive_regulation of Transcription of Mmp2 4 0.46 2.63 1.37
90 INT120860 Positive_regulation of Gene_expression of Col1a1 12 0.44 4.84 1.34
91 INT152951 Negative_regulation of LEF1 5 0.41 3.22 1.31
92 INT238074 Negative_regulation of Positive_regulation of Mmp2 4 0.34 1.79 1.31
93 INT173892 Phosphorylation of TGFB1 8 0.79 2.63 1.3
94 INT112650 Positive_regulation of Col1a1 3 0.30 5.96 1.3
95 INT59473 Negative_regulation of Col1a1 4 0.25 1.33 1.24
96 INT71845 Positive_regulation of Positive_regulation of Col1a1 1 0.34 0.15 1.23
97 INT140033 Positive_regulation of Gene_expression of Col1a1 6 0.14 3.68 1.2
98 INT138726 Positive_regulation of Gene_expression of Msx1 5 0.53 1.73 1.2
99 INT108519 Binding of Lrp6 8 0.44 1.47 1.19
100 INT165338 Binding of Dkk1 4 0.37 3.64 1.04
101 INT96581 Negative_regulation of Negative_regulation of MMP2 4 0.57 3.1 1.04
102 INT84511 Positive_regulation of Tfap2a 3 0.27 0.72 1.04
103 INT120858 Positive_regulation of Localization of Tgfb1 7 0.68 1.46 1.03
104 INT156614 Regulation of Gene_expression of COL1A1 6 0.33 2.51 0.99
105 INT129997 Protein_catabolism of Col1a1 5 0.96 3.43 0.96
106 INT180925 Positive_regulation of Localization of Mmp2 4 0.54 3.21 0.95
107 INT128717 Regulation of Tgfb1 6 0.61 1.94 0.94
108 INT29501 Positive_regulation of Localization of Mmp2 3 0.60 0.42 0.94
109 INT123852 Negative_regulation of Positive_regulation of Tgfb1 3 0.28 1.69 0.94
110 INT243974 Binding of Tfap2a 7 0.18 1.36 0.93
111 INT29500 Regulation of Localization of Mmp2 3 0.53 0.47 0.92
112 INT55738 Positive_regulation of Transcription of MMP2 3 0.65 1.79 0.92
113 INT243611 Gene_expression of Twist2 5 0.67 2.85 0.86
114 INT8888 Regulation of Col1a1 4 0.13 1.97 0.86
115 INT139322 Negative_regulation of Negative_regulation of Tgfb1 1 0.53 0 0.86
116 INT85148 Transcription of Tgfb1 5 0.52 1.91 0.84
117 INT165337 Regulation of Dkk1 3 0.44 2.16 0.83
118 INT221796 Positive_regulation of Gene_expression of Tfap2a 2 0.10 1.19 0.83
119 INT258932 Positive_regulation of TBX1 3 0.39 2.73 0.82
120 INT278710 Phosphorylation of LEF1 1 0.05 0.76 0.82
121 INT119102 Gene_expression of PDGFRA 13 0.75 11.99 0.81
122 INT192156 Negative_regulation of Col1a1 6 0.39 3.92 0.8
123 INT152290 Regulation of Transcription of Mmp2 1 0.27 0.15 0.8
124 INT139323 Positive_regulation of Negative_regulation of Tgfb1 1 0.45 0 0.79
125 INT14871 Binding of TGFB3 3 0.13 1.2 0.78
126 INT188251 Localization of DKK1 6 0.50 3.26 0.77
127 INT242131 Localization of Dkk1 5 0.79 6 0.76
128 INT291617 Negative_regulation of Transcription of TGFB1 2 0.15 0.61 0.76
129 INT123773 Positive_regulation of Positive_regulation of Mmp2 2 0.17 1.83 0.75
130 INT207535 Transcription of Tfap2a 3 0.31 0.98 0.74
131 INT265557 Protein_catabolism of Mmp2 3 0.55 3.15 0.73
132 INT95617 Regulation of Msx1 2 0.56 1.05 0.73
133 INT344975 Regulation of Gene_expression of Dkk1 1 0.44 3.44 0.73
134 INT129882 Positive_regulation of Gene_expression of Dkk1 4 0.69 4.62 0.72
135 INT266797 Negative_regulation of Negative_regulation of Mmp2 1 0.05 0.96 0.7
136 INT143953 Regulation of Positive_regulation of MMP2 3 0.44 2.25 0.69
137 INT135197 Gene_expression of Tfap2a 1 0.45 0.48 0.69
138 INT89520 Regulation of COL1A1 8 0.32 3.21 0.66
139 INT114909 Negative_regulation of Localization of TGFB1 5 0.36 1.37 0.66
140 INT75043 Binding of Msx1 6 0.35 2.36 0.65
141 INT111891 Regulation of Transcription of Tgfb1 1 0.04 0.68 0.64
142 INT114910 Negative_regulation of Positive_regulation of TGFB1 3 0.34 0.92 0.6
143 INT207529 Localization of Tfap2a 2 0.34 0.13 0.6
144 INT173891 Positive_regulation of Phosphorylation of TGFB1 4 0.49 2 0.59
145 INT32921 Positive_regulation of Msx1 4 0.47 0.99 0.57
146 INT283569 Protein_catabolism of Mmp2 5 0.77 3.25 0.56
147 INT243970 Phosphorylation of Tfap2a 2 0.25 0.56 0.56
148 INT279846 Gene_expression of Nipbl 1 0.68 11.1 0.56
149 INT244679 Binding of Mmp2 4 0.30 3.75 0.54
150 INT342614 Positive_regulation of Binding of Mmp2 1 0.46 0.6 0.54
151 INT68092 Negative_regulation of Localization of COL1A1 1 0.48 0 0.53
152 INT108629 Negative_regulation of Regulation of MMP2 1 0.41 0.7 0.52
153 INT96580 Negative_regulation of Protein_catabolism of MMP2 2 0.55 0.6 0.51
154 INT166100 Phosphorylation of MMP2 1 0.32 0.56 0.51
155 INT8886 Regulation of Transcription of Col1a1 1 0.04 0 0.5
156 INT145144 Positive_regulation of Negative_regulation of Mmp2 1 0.11 0.7 0.46
157 INT159221 Negative_regulation of TBX1 4 0.41 4.22 0.43
158 INT244683 Regulation of Positive_regulation of Mmp2 2 0.36 0.78 0.43
159 INT247307 Negative_regulation of Msx1 3 0.22 0.11 0.42
160 INT65606 Binding of TBX1 2 0.30 3.13 0.41
161 INT27659 Localization of TGFB3 3 0.29 0.52 0.4
162 INT320812 Positive_regulation of Localization of COL1A1 1 0.05 1.04 0.4
163 INT163709 Regulation of Negative_regulation of COL1A1 1 0.29 0.93 0.34
164 INT111230 Transcription of LEF1 3 0.30 1.72 0.33
165 INT242130 Positive_regulation of Positive_regulation of Dkk1 2 0.49 1.71 0.33
166 INT344976 Positive_regulation of Negative_regulation of Dkk1 1 0.49 1.13 0.33
167 INT156411 Gene_expression of Pdgfra 8 0.75 5.5 0.3
168 INT254811 Localization of Col1a1 3 0.29 1.39 0.3
169 INT344977 Negative_regulation of Localization of Dkk1 2 0.42 2.57 0.3
170 INT291615 Negative_regulation of Localization of Col1a1 1 0.06 1.28 0.3
171 INT14873 Positive_regulation of Gene_expression of TGFB3 2 0.25 1.14 0.29
172 INT19917 Regulation of DKK1 3 0.24 1.61 0.28
173 INT269082 Gene_expression of TBX1 1 0.14 0.36 0.28
174 INT126512 Negative_regulation of Gene_expression of Col1a1 3 0.39 2.2 0.27
175 INT335875 Regulation of Lrp6 1 0.57 0.43 0.27
176 INT214128 Negative_regulation of Gene_expression of Msx1 3 0.53 1.25 0.26
177 INT176464 Protein_catabolism of Col1a1 1 0.19 0.83 0.26
178 INT29504 Negative_regulation of Localization of Mmp2 1 0.58 0.13 0.26
179 INT156410 Positive_regulation of Pdgfra 3 0.08 1.51 0.25
180 INT148219 Regulation of Localization of Mmp2 1 0.02 0.69 0.25
181 INT271432 Positive_regulation of Regulation of Col1a1 1 0.10 0.61 0.24
182 INT306427 Localization of TBX1 1 0.20 1.08 0.23
183 INT306428 Positive_regulation of Localization of TBX1 1 0.14 1.08 0.23
184 INT225109 Regulation of Localization of COL1A1 1 0.05 0.41 0.23
185 INT299545 Positive_regulation of Binding of TGFB1 2 0.06 1.08 0.22
186 INT147840 Gene_expression of Tgfb3 1 0.03 0 0.22
187 INT147841 Positive_regulation of Gene_expression of Tgfb3 1 0.02 0 0.22
188 INT218694 Binding of Col1a1 2 0.21 1.52 0.21
189 INT61823 Positive_regulation of TGFB3 2 0.01 1.64 0.2
190 INT243604 Localization of Twist2 1 0.65 0.54 0.2
191 INT243599 Positive_regulation of Localization of Twist2 1 0.43 0.54 0.2
192 INT291081 Positive_regulation of Protein_catabolism of Mmp2 1 0.29 0.96 0.2
193 INT114371 Negative_regulation of Tcf7l2 1 0.05 0.7 0.2
194 INT291083 Negative_regulation of Protein_catabolism of Mmp2 1 0.24 0.96 0.2
195 INT279853 Negative_regulation of Gene_expression of Nipbl 1 0.51 2.37 0.19
196 INT159231 Positive_regulation of PDGFRA 3 0.47 2.39 0.18
197 INT120859 Positive_regulation of Localization of Col1a1 1 0.16 0.05 0.18
198 INT162939 Binding of Tfap2a 1 0.26 0.34 0.17
199 INT162940 Negative_regulation of Tfap2a 1 0.32 0.34 0.17
200 INT187816 Positive_regulation of Transcription of Col1a1 1 0.06 0.82 0.17
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