GO:0060333

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Name interferon-gamma-mediated signaling pathway
Categary Process
Go Slim No
Go Link GO:0060333
Unique Molecular Interactions 886
Total Molecular Interactions 1365
Total Single Events 8781
Pain Genes Associated 61

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for interferon-gamma-mediated signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for interferon-gamma-mediated signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65
2 INT220623 Binding of Stat1 and Bace1 11 0.25 10.33 3.81
3 INT180984 IRF6 Positive_regulation of Localization of IL8 7 0.11 2.13 3.47
4 INT152035 Binding of HLA-A and MRAP 2 0.31 6.95 3.4
5 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81
6 INT319581 Binding of PIAS1 and TNFSF14 1 0.02 1.58 2.13
7 INT88883 IRF6 Positive_regulation of Nfkb1 1 0.11 0.53 2.01
8 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95
9 INT205152 Binding of CD44 and MMP9 23 0.35 17.13 1.85
10 INT267133 Binding of ICAM1 and VCAM1 25 0.32 25.43 1.83
11 INT172047 Binding of HLA-A and LRRC23 1 0.22 3.32 1.64
12 INT174503 Binding of HLA-B and KIR3DL1 6 0.37 3.48 1.61
13 INT107965 Binding of HLA-B and Mefv 2 0.34 3.91 1.61
14 INT113337 EPO Positive_regulation of JAK2 1 0.76 2.8 1.55
15 INT174508 Binding of CD4 and HLA-B 1 0.14 4.68 1.53
16 INT293009 IRF6 Positive_regulation of Positive_regulation of CA2 1 0.04 0.66 1.49
17 INT318491 IRF6 Positive_regulation of FPR2 1 0.10 6.14 1.44
18 INT55837 Binding of HLA-B and PHB2 3 0.20 3.52 1.37
19 INT160587 IFNG Positive_regulation of Gene_expression of OPRM1 1 0.18 0.54 1.35
20 INT294775 IRF6 Positive_regulation of TLR4 6 0.08 2.04 1.32
21 INT112961 NGF Positive_regulation of ICAM1 1 0.40 0.96 1.28
22 INT177232 ICAM1 Regulation of Gene_expression of Vcam1 1 0.03 5.52 1.28
23 INT34052 POMC Regulation of Gene_expression of IFNG 1 0.11 0 1.27
24 INT151648 TLR4 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
25 INT151657 Vcam1 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
26 INT151658 F3 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
27 INT172141 IL10 Negative_regulation of Gene_expression of HLA-DRA 2 0.14 0.89 1.23
28 INT184402 Binding of HLA-DRB4 and HLA-E 1 0.00 3.1 1.19
29 INT289465 IRF6 Positive_regulation of IL1B 3 0.05 0.9 1.16
30 INT340439 Binding of HLA-DMA and SUGT1 1 0.00 4.1 1.16
31 INT197051 Binding of HLA-E and ATP8A1 1 0.00 6.52 1.14
32 INT107269 Binding of HLA-A and NCR3 1 0.35 1.42 1.1
33 INT107266 Binding of HLA-DRB1 and TNF 1 0.29 1.41 1.1
34 INT122889 Ifng Positive_regulation of Gene_expression of HLA-E 1 0.02 0.97 1.1
35 INT107265 Binding of HLA-DRB1 and ITGAL 1 0.01 1.41 1.1
36 INT230019 Binding of HLA-B and ERAL1 1 0.00 2.23 1.1
37 INT107263 Binding of HLA-DRB1 and NCR3 1 0.40 1.42 1.1
38 INT107267 Binding of HLA-A and TNF 1 0.34 1.41 1.1
39 INT71176 Binding of ICAM1 and ITGB2 4 0.21 4.93 1.07
40 INT185373 IRF6 Positive_regulation of Gene_expression of TLR2 1 0.08 2.96 1.04
41 INT318490 IRF6 Positive_regulation of LTB4R 1 0.01 4.39 1.03
42 INT88881 Negative_regulation of IRF6 Positive_regulation of Nfkb1 1 0.09 0.27 1.03
43 INT293014 IRF6 Positive_regulation of Localization of CA2 1 0.04 0.71 1.02
44 INT74934 Regulation of IRF6 Positive_regulation of Nfkb1 1 0.01 0.52 1.02
45 INT88887 IRF6 Positive_regulation of Transcription of Nos2 1 0.21 0.27 1.02
46 INT74933 IRF6 Positive_regulation of Nfkb1 1 0.02 0.52 1.01
47 INT88884 IRF6 Regulation of Nos2 1 0.12 0.26 1
48 INT88886 IRF6 Positive_regulation of Nos2 1 0.22 0.26 1
49 INT88888 Regulation of IRF6 Positive_regulation of Nos2 1 0.20 0.26 1
50 INT316128 TCF21 Negative_regulation of Gene_expression of HLA-DRA 1 0.07 0.13 0.99
51 INT77142 Binding of IFNG and IL4 2 0.03 1.16 0.95
52 INT133050 TNF Positive_regulation of Gene_expression of ICAM1 3 0.67 1.91 0.94
53 INT139330 Binding of SGCG and Stat1 1 0.37 0.75 0.94
54 INT285418 IRF6 Positive_regulation of Localization of IL6 3 0.05 0.66 0.93
55 INT227325 Binding of IRF6 and Cd14 1 0.01 2.51 0.93
56 INT143323 Binding of HLA-B and HP 1 0.04 0.95 0.93
57 INT289461 IRF6 Positive_regulation of ICAM1 1 0.08 0.61 0.91
58 INT343834 Binding of CD14 and IRF6 1 0.02 2.08 0.9
59 INT80132 Binding of HLA-B and TNF 1 0.04 1.15 0.89
60 INT272144 PTAFR Positive_regulation of HRASLS 1 0.08 1.08 0.89
61 INT166983 Binding of HLA-B and HSPG2 4 0.08 4.66 0.88
62 INT343847 IRF6 Positive_regulation of TBCE 1 0.01 1.11 0.87
63 INT97795 IRF6 Positive_regulation of Localization of TNF 3 0.09 1.57 0.86
64 INT167947 Binding of STAT1 and Oprm1 1 0.00 0 0.86
65 INT342986 PTAFR Positive_regulation of Gene_expression of IL6 1 0.14 0.39 0.84
66 INT340437 Binding of SERPINH1 and HLA-DRB4 1 0.00 2.26 0.84
67 INT94331 IFNG Positive_regulation of CXCL10 4 0.11 1.31 0.82
68 INT188567 IRF6 Positive_regulation of Gene_expression of CD28 1 0.05 1.28 0.82
69 INT88885 IRF6 Positive_regulation of Gene_expression of Nos2 1 0.21 0.1 0.81
70 INT286346 IRF6 Positive_regulation of IL8 3 0.03 0.88 0.8
71 INT342992 Negative_regulation of PTAFR Negative_regulation of Gene_expression of HIST2H2AA3 1 0.01 0.4 0.78
72 INT182814 Binding of ICAM1 and PECAM1 2 0.02 3.32 0.77
73 INT134049 Jak2 Positive_regulation of Gsk3b 1 0.37 0.22 0.77
74 INT149192 TNF Positive_regulation of Gene_expression of VCAM1 3 0.57 1.4 0.76
75 INT173112 IL1B Positive_regulation of Gene_expression of VCAM1 2 0.43 1.34 0.76
76 INT134043 Jak2 Positive_regulation of Akt1 1 0.31 0.22 0.76
77 INT134051 Jak2 Positive_regulation of Stat3 1 0.44 0.22 0.76
78 INT221415 IRF6 Positive_regulation of Gene_expression of IL10 2 0.05 1.73 0.75
79 INT250959 Binding of HLA-B and SOD1 1 0.05 0.75 0.75
80 INT142847 IRF6 Positive_regulation of IL6 5 0.07 1.09 0.73
81 INT121843 HLA-DRB5 Negative_regulation of Accn4 1 0.00 0.54 0.73
82 INT146460 IFNG Positive_regulation of Gene_expression of TNFRSF10D 1 0.03 1.46 0.72
83 INT172097 Binding of HLA-E and Trav6-3 10 0.02 3.71 0.71
84 INT272147 PTAFR Positive_regulation of CA2 1 0.13 0 0.71
85 INT146461 IFNG Positive_regulation of NFKB1 1 0.01 1.44 0.71
86 INT240729 Binding of CRP and HLA-A 1 0.11 2.18 0.71
87 INT99818 IFNG Positive_regulation of Gene_expression of APP 1 0.04 0.82 0.7
88 INT104835 IRF6 Positive_regulation of IL10 4 0.32 0.91 0.69
89 INT28711 Binding of HLA-B and MRAP 2 0.23 0.96 0.69
90 INT73823 TFF2 Positive_regulation of Gene_expression of VCAM1 1 0.04 0.59 0.69
91 INT79937 TAC1 Positive_regulation of Gene_expression of VCAM1 1 0.20 0.15 0.68
92 INT119105 Binding of FCGR1A and TNF 1 0.03 1.16 0.67
93 INT119106 Negative_regulation of Binding of FCGR1A and TNF 1 0.03 1.16 0.67
94 INT343851 Positive_regulation of Binding of IRF6 and TLR4 1 0.07 1.96 0.66
95 INT103868 IFNG Positive_regulation of Hmox1 1 0.09 0.83 0.65
96 INT318476 IRF6 Positive_regulation of Localization of RETNLB 1 0.00 1.42 0.65
97 INT66603 TFF2 Positive_regulation of Gene_expression of ICAM1 1 0.02 0 0.64
98 INT231534 Binding of JAK1 and SOAT1 1 0.01 0.6 0.64
99 INT142076 IL4 Negative_regulation of Gene_expression of IFNG 1 0.01 1.58 0.64
100 INT103870 IRF6 Positive_regulation of Hmox1 1 0.14 0.83 0.64
101 INT64956 IRF6 Positive_regulation of Gene_expression of IL6 4 0.19 1.4 0.63
102 INT223155 Binding of Mapk14 and Stat4 1 0.36 0.84 0.63
103 INT169101 Binding of HLA-A and HLA-DRB1 1 0.24 1.09 0.63
104 INT174500 Positive_regulation of Binding of CD4 and HLA-B 1 0.21 2.33 0.63
105 INT346141 ADM Positive_regulation of Gene_expression of ICAM1 1 0.19 1.75 0.63
106 INT66601 WDR87 Positive_regulation of Gene_expression of ICAM1 1 0.00 0 0.63
107 INT66604 SARDH Positive_regulation of Gene_expression of ICAM1 1 0.01 0 0.63
108 INT31942 Binding of FCGR1A and Oprd1 1 0.00 0 0.62
109 INT176475 IL1B Positive_regulation of Gene_expression of ICAM1 1 0.02 0.56 0.62
110 INT115592 IRF6 Positive_regulation of Gene_expression of FAS 1 0.34 0.34 0.62
111 INT182815 Binding of CD63 and ICAM1 1 0.00 1.63 0.61
112 INT85489 IRF6 Negative_regulation of PLOD1 1 0.01 0.16 0.61
113 INT85488 Negative_regulation of IRF6 Negative_regulation of PLOD1 1 0.01 0.16 0.61
114 INT122096 Binding of HLA-B and SFTPA1 2 0.04 1.81 0.6
115 INT342981 PTAFR Regulation of SFTPA1 1 0.03 0.38 0.6
116 INT92996 Binding of VCAM1 and GORASP1 1 0.39 0.33 0.6
117 INT272146 PTAFR Positive_regulation of Localization of IL8 3 0.38 0.28 0.59
118 INT174504 Binding of HLA-B and KIR3DL2 2 0.24 1.69 0.59
119 INT318481 IRF6 Positive_regulation of Gene_expression of FPR2 1 0.14 5.09 0.59
120 INT318487 Negative_regulation of IRF6 Positive_regulation of FPR2 1 0.09 1.39 0.59
121 INT263454 Negative_regulation of IRF6 Positive_regulation of TNF 1 0.12 0.49 0.59
122 INT87683 Binding of HLA-B and Prnd 1 0.00 0.59 0.59
123 INT87024 Positive_regulation of ZAK Positive_regulation of Localization of IFNG 2 0.05 0.81 0.58
124 INT197050 Binding of HLA-DOA and HLA-E 2 0.08 1.73 0.58
125 INT184100 Il6 Positive_regulation of Stat1 1 0.16 0.68 0.58
126 INT162742 Binding of HLA-A and KIR3DL1 1 0.40 0.68 0.58
127 INT277828 Negative_regulation of Binding of ICAM1 and ITGAL 2 0.22 1.27 0.57
128 INT92999 Binding of CD40 and VCAM1 1 0.39 0.33 0.57
129 INT236783 IRF6 Negative_regulation of Gene_expression of TLR4 1 0.01 1.17 0.57
130 INT341594 Binding of ESR1 and HLA-B 1 0.01 0.72 0.57
131 INT294708 CRP Positive_regulation of Gene_expression of VCAM1 2 0.31 1.92 0.56
132 INT27871 Binding of FCGR1B and HSPD1 1 0.01 1.93 0.56
133 INT66600 TFF2 Regulation of Positive_regulation of ICAM1 1 0.01 0 0.56
134 INT27872 Positive_regulation of Binding of FCGR1B and HSPD1 1 0.01 1.93 0.56
135 INT91428 CD44 Positive_regulation of Binding of MMRN1 1 0.24 0.85 0.55
136 INT286349 IRF6 Positive_regulation of Localization of IL10 1 0.03 1.22 0.55
137 INT133049 TNF Positive_regulation of ICAM1 4 0.47 2.49 0.54
138 INT137162 IFNG Positive_regulation of Gene_expression of CXCL9 1 0.45 0.62 0.54
139 INT318478 Negative_regulation of IRF6 Positive_regulation of LTB4R 1 0.01 2.38 0.53
140 INT120383 PRKCD Positive_regulation of Localization of EPHB2 1 0.29 0.42 0.52
141 INT120384 PRKCD Positive_regulation of Localization of HSPG2 1 0.29 0.42 0.51
142 INT137137 Binding of HIVEP1 and ICAM1 1 0.01 0.68 0.51
143 INT254356 Binding of IFNG and IL1B 1 0.00 1.87 0.51
144 INT33415 KNG1 Positive_regulation of GBP1 1 0.02 0.43 0.51
145 INT143504 IFNG Positive_regulation of Gene_expression of Aif1 1 0.04 1.26 0.51
146 INT92997 Positive_regulation of SFTPA1 Positive_regulation of Binding of ICAM1 1 0.15 0.26 0.51
147 INT120852 PRL Positive_regulation of IRF1 1 0.44 0.99 0.51
148 INT36084 Binding of HLA-DRB4 and Igkv16-104 1 0.04 1.01 0.51
149 INT120382 PRKCD Positive_regulation of Localization of DYT10 1 0.29 0.42 0.51
150 INT343859 Binding of IRF6 and TBCE 1 0.01 1.1 0.51
151 INT121821 Binding of STAT1 and Olr1583 1 0.00 0.21 0.51
152 INT97800 Gm5564 Regulation of IRF6 1 0.00 0.07 0.5
153 INT343825 IRF6 Regulation of Gene_expression of FUT1 1 0.00 1.74 0.5
154 INT341593 Binding of HLA-E and IL23R 1 0.15 1.15 0.5
155 INT217037 Binding of IRF6 and Il12a 1 0.01 0.08 0.5
156 INT169400 Negative_regulation of IRF6 Positive_regulation of Gene_expression of Il1b 1 0.50 0.62 0.5
157 INT289464 Negative_regulation of IRF6 Positive_regulation of ICAM1 1 0.07 0.31 0.5
158 INT36143 Binding of SERPINH1 and HLA-B 1 0.00 0.66 0.49
159 INT120854 IRF1 Positive_regulation of Localization of TNF 1 0.20 0.94 0.49
160 INT84515 IRF6 Positive_regulation of Gene_expression of F2 1 0.02 0.15 0.49
161 INT348173 Binding of HLA-B and IL23R 1 0.15 0.92 0.49
162 INT135586 CSF2 Regulation of ICAM1 1 0.13 1.3 0.49
163 INT138927 Ifng Positive_regulation of Gene_expression of Stat1 1 0.29 0.7 0.49
164 INT348177 Binding of HLA-B and ERAP1 1 0.14 0.92 0.49
165 INT289462 Negative_regulation of IRF6 Positive_regulation of IL1B 2 0.04 0.31 0.48
166 INT172096 Binding of HLA-E and Il27ra 2 0.01 1.32 0.48
167 INT127663 IRF6 Positive_regulation of PDE4A 1 0.14 0.76 0.48
168 INT289463 IRF6 Positive_regulation of Localization of IL1B 1 0.05 0.52 0.48
169 INT328936 Binding of HLA-B and KIR3DS1 1 0.25 0.7 0.48
170 INT263977 PROC Negative_regulation of JAK2 1 0.00 0.93 0.47
171 INT134048 Jak2 Regulation of Pik3cb 1 0.23 0.13 0.47
172 INT134045 Jak2 Regulation of Stat3 1 0.26 0.13 0.47
173 INT134042 Jak2 Regulation of Akt1 1 0.18 0.13 0.47
174 INT134046 Jak2 Regulation of Gsk3b 1 0.22 0.13 0.47
175 INT217040 Negative_regulation of IRF6 Positive_regulation of CCL2 1 0.00 1.24 0.47
176 INT340440 Binding of HLA-B and BTG3 1 0.05 1.57 0.47
177 INT342983 HCL1 Positive_regulation of PTAFR 1 0.03 0.07 0.47
178 INT217039 IRF6 Positive_regulation of CCL2 1 0.00 1.24 0.47
179 INT196634 IFNG Negative_regulation of DNAH8 1 0.03 1.49 0.47
180 INT134050 Positive_regulation of Jak2 Regulation of Stat3 1 0.44 0.13 0.47
181 INT193480 Binding of ABCA1 and IRF6 1 0.00 1.08 0.46
182 INT48848 Binding of HLA-B and HLA-E 3 0.34 1.95 0.45
183 INT103871 Negative_regulation of IRF6 Positive_regulation of Hmox1 1 0.12 0.61 0.45
184 INT45035 Binding of HLA-B and HLA-DRB4 2 0.16 0.74 0.44
185 INT79151 Binding of HLA-B and OLAH 1 0.01 0.79 0.44
186 INT84517 IRF6 Positive_regulation of TF 1 0.14 0.19 0.44
187 INT279360 ADA Negative_regulation of Gene_expression of IFNG 1 0.06 0.51 0.44
188 INT188564 IRF6 Positive_regulation of Gene_expression of PRF1 1 0.01 0.44 0.44
189 INT188565 IRF6 Regulation of Gene_expression of CD28 1 0.03 0.7 0.43
190 INT157343 Binding of AQP4 and HLA-DPB1 1 0.30 0.89 0.43
191 INT189154 MTNR1B Positive_regulation of Gene_expression of IFNG 1 0.01 0.06 0.43
192 INT340438 Binding of HLA-DMA and MRAP 1 0.02 1.69 0.43
193 INT342987 TRPV1 Positive_regulation of Localization of PTAFR 1 0.33 0.84 0.43
194 INT174507 Binding of HLA-B and LILRB4 1 0.02 1.16 0.43
195 INT243682 IRF6 Positive_regulation of NEU2 1 0.01 0.18 0.43
196 INT343853 IRF6 Positive_regulation of PECAM1 1 0.00 0.53 0.43
197 INT188562 IRF6 Regulation of Gene_expression of PRF1 1 0.01 0.7 0.43
198 INT79150 HLA-B Positive_regulation of OLAH 1 0.02 0.77 0.43
199 INT174501 Binding of HLA-B and HLA-DOA 2 0.03 1.84 0.42
200 INT316121 IL10 Regulation of Gene_expression of HLA-DRA 1 0.09 0.46 0.42

Single Events

The table below shows the top 100 pain related interactions that have been reported for interferon-gamma-mediated signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in interferon-gamma-mediated signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT1878 Binding of HLA-B 440 0.48 321.16 127.36
2 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6
3 INT749 Gene_expression of HLA-B 341 0.75 224.12 77.37
4 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57
5 INT16364 Gene_expression of HLA-DRA 234 0.78 118.81 45.01
6 INT62827 Positive_regulation of ICAM1 184 0.70 180.95 36.28
7 INT11325 Gene_expression of HLA-E 209 0.76 98.05 33.72
8 INT62830 Gene_expression of VCAM1 149 0.78 125.23 32.4
9 INT10506 Gene_expression of PTAFR 86 0.76 37.57 28.58
10 INT22045 Gene_expression of IRF6 158 0.75 58.07 27.81
11 INT64499 Positive_regulation of IRF6 123 0.49 52.73 27.51
12 INT5055 Positive_regulation of IFNG 89 0.69 64.03 23.05
13 INT19330 Binding of HLA-A 99 0.48 76.26 22.85
14 INT1876 Positive_regulation of HLA-B 82 0.69 52.16 21.08
15 INT11161 Gene_expression of HLA-DRB1 121 0.78 75.33 20.96
16 INT97798 Localization of IRF6 86 0.73 33.27 20.94
17 INT63340 Positive_regulation of Gene_expression of ICAM1 109 0.70 90.82 20.61
18 INT5160 Localization of PTAFR 61 0.80 42.6 19.16
19 INT62826 Negative_regulation of Gene_expression of ICAM1 75 0.58 46.39 17.72
20 INT25223 Positive_regulation of Gene_expression of IFNG 41 0.67 36.97 15.89
21 INT37722 Gene_expression of NCAM1 103 0.75 81.57 14.18
22 INT22046 Negative_regulation of IRF6 52 0.43 25.69 14.13
23 INT11696 Gene_expression of HLA-A 50 0.78 41.25 14.1
24 INT56651 Binding of HLA-DRB1 58 0.48 52.25 13.68
25 INT4931 Localization of IFNG 53 0.78 33.25 13.65
26 INT11699 Binding of HLA-E 85 0.47 52.51 13.41
27 INT99586 Binding of IRF6 60 0.36 27.87 13.2
28 INT63361 Gene_expression of CD44 126 0.77 71.58 12.96
29 INT5057 Negative_regulation of Gene_expression of IFNG 23 0.58 8.33 12.3
30 INT73829 Positive_regulation of Gene_expression of VCAM1 41 0.61 35.96 11.92
31 INT13303 Positive_regulation of PTAFR 40 0.69 16.27 11.56
32 INT65713 Localization of ICAM1 42 0.81 39.55 11.49
33 INT56448 Regulation of ICAM1 52 0.60 55.1 10.96
34 INT19944 Negative_regulation of IFNG 39 0.58 22.35 10.91
35 INT23402 Binding of HLA-DOA 74 0.48 52.01 10.89
36 INT23177 Negative_regulation of Gene_expression of HLA-DRA 50 0.44 16.99 10.55
37 INT80549 Binding of ICAM1 53 0.47 42.76 9.72
38 INT63341 Negative_regulation of ICAM1 42 0.59 30.45 9.5
39 INT3925 Negative_regulation of HLA-B 29 0.42 20.19 9.46
40 INT62829 Positive_regulation of VCAM1 39 0.70 38.42 9.15
41 INT63338 Regulation of Gene_expression of ICAM1 42 0.62 28.26 9.06
42 INT3353 Localization of HLA-B 25 0.75 16.05 8.62
43 INT28671 Positive_regulation of Gene_expression of HLA-E 43 0.67 22.85 8.39
44 INT30526 Negative_regulation of PTAFR 15 0.58 8.15 8.19
45 INT846 Positive_regulation of B2M 42 0.70 29.78 8.06
46 INT5284 Regulation of HLA-B 25 0.59 12.91 7.74
47 INT6596 Positive_regulation of HLA-DRB1 33 0.61 27.01 7.26
48 INT138922 Positive_regulation of Stat1 57 0.69 28.35 7.2
49 INT13520 Binding of HLA-DRB4 30 0.42 32.65 6.74
50 INT17618 Gene_expression of B2M 36 0.66 16.39 6.68
51 INT23246 Gene_expression of HLA-DRB4 37 0.64 36.79 6.61
52 INT10507 Positive_regulation of Gene_expression of PTAFR 15 0.61 10.24 6.61
53 INT76096 Positive_regulation of Gene_expression of IRF6 37 0.49 14.24 6.39
54 INT150417 Negative_regulation of Gene_expression of IRF6 20 0.41 11.48 6.28
55 INT57256 Gene_expression of HLA-DQA2 52 0.55 23.87 6.27
56 INT48234 Negative_regulation of Gene_expression of PTAFR 11 0.57 3.97 6.25
57 INT163756 Phosphorylation of Stat1 45 0.82 14.51 6.11
58 INT17551 Positive_regulation of Gene_expression of HLA-DRA 31 0.70 15.39 6
59 INT18967 Positive_regulation of Gene_expression of HLA-DRB1 14 0.49 13.56 5.99
60 INT15803 Regulation of IFNG 21 0.44 12.57 5.98
61 INT4697 Positive_regulation of Gene_expression of HLA-B 32 0.61 17.32 5.97
62 INT52907 Regulation of Gene_expression of HLA-DRA 28 0.34 5.94 5.96
63 INT138915 Gene_expression of Stat1 144 0.77 69.53 5.85
64 INT23401 Gene_expression of HLA-DOA 91 0.30 38.21 5.52
65 INT65712 Positive_regulation of Localization of ICAM1 14 0.70 16.72 5.5
66 INT118870 Positive_regulation of STAT1 36 0.67 26.18 5.46
67 INT14357 Positive_regulation of FCGR1A 10 0.44 7.14 5.4
68 INT64767 Negative_regulation of Gene_expression of HLA-E 18 0.57 12.64 5.23
69 INT15797 Positive_regulation of HLA-E 36 0.67 15.17 5.07
70 INT113161 Gene_expression of Jak2 50 0.77 42.52 4.76
71 INT56032 Positive_regulation of NCAM1 38 0.49 26.01 4.68
72 INT138779 Positive_regulation of Localization of IRF6 25 0.45 11.51 4.51
73 INT10896 Regulation of PTAFR 16 0.61 4.22 4.5
74 INT62821 Negative_regulation of Gene_expression of VCAM1 21 0.54 12.24 4.41
75 INT223153 Binding of Stat4 5 0.34 7.98 4.28
76 INT153410 Negative_regulation of Jak2 5 0.59 10.71 3.98
77 INT118583 Positive_regulation of IRF1 10 0.68 3.75 3.91
78 INT15133 Regulation of HLA-DRA 19 0.34 5.84 3.9
79 INT174195 Negative_regulation of HLA-E 31 0.42 11.98 3.88
80 INT96071 Localization of PIAS1 6 0.71 4.44 3.79
81 INT34054 Regulation of Gene_expression of IFNG 8 0.42 3.69 3.76
82 INT97799 Regulation of IRF6 23 0.26 6.54 3.75
83 INT123908 Positive_regulation of HLA-DQB1 12 0.21 10.5 3.71
84 INT13302 Binding of PTAFR 20 0.48 7.03 3.7
85 INT79477 Binding of HLA-DMA 19 0.26 13.78 3.47
86 INT10586 Localization of B2M 15 0.68 8.67 3.46
87 INT8481 Regulation of PIAS1 4 0.45 0.47 3.44
88 INT76098 Positive_regulation of Positive_regulation of IRF6 16 0.27 6.05 3.35
89 INT87027 Positive_regulation of Localization of IFNG 12 0.67 5.78 3.35
90 INT118035 Positive_regulation of JAK1 23 0.67 10.57 3.29
91 INT19331 Positive_regulation of HLA-A 12 0.49 7.72 3.28
92 INT28249 Positive_regulation of HLA-DRA 25 0.70 13.63 3.25
93 INT184060 Negative_regulation of Stat1 28 0.58 17.44 3.19
94 INT31940 Binding of FCGR1A 6 0.35 2.16 3.1
95 INT77604 Positive_regulation of Binding of VCAM1 4 0.47 6.54 3.06
96 INT181008 Negative_regulation of Localization of IRF6 13 0.14 2.32 2.96
97 INT16959 Positive_regulation of Binding of HLA-B 8 0.50 6.77 2.96
98 INT2249 Negative_regulation of Binding of HLA-B 5 0.54 6.82 2.94
99 INT77602 Binding of VCAM1 8 0.41 8.66 2.86
100 INT94327 Phosphorylation of Stat1 9 0.80 2.06 2.8
101 INT271447 Positive_regulation of Positive_regulation of HLA-DQB1 1 0.06 5.87 2.8
102 INT79476 Gene_expression of HLA-DMA 23 0.38 9.5 2.76
103 INT119839 Gene_expression of STAT1 17 0.75 8.36 2.7
104 INT79938 Regulation of Gene_expression of VCAM1 12 0.61 11.22 2.64
105 INT95164 Localization of NCAM1 13 0.78 6.06 2.62
106 INT65472 Binding of HLA-G 9 0.36 6.06 2.6
107 INT51683 Regulation of Gene_expression of PTAFR 11 0.60 5.06 2.59
108 INT51680 Protein_catabolism of PTAFR 7 0.64 3.69 2.59
109 INT91669 Negative_regulation of Localization of IFNG 5 0.57 4.1 2.58
110 INT237700 Regulation of Negative_regulation of IRF6 2 0.11 1.08 2.58
111 INT113160 Negative_regulation of Jak2 26 0.58 20.3 2.57
112 INT19492 Regulation of B2M 16 0.60 10.97 2.55
113 INT89281 Negative_regulation of Gene_expression of HLA-DRB1 10 0.30 5.9 2.55
114 INT18969 Gene_expression of HLA-DQA1 29 0.65 12.19 2.54
115 INT91429 Binding of CD44 34 0.41 17.67 2.51
116 INT54720 Positive_regulation of HLA-DRB5 9 0.34 6.7 2.51
117 INT337317 Positive_regulation of Localization of PTAFR 2 0.51 3.88 2.5
118 INT16964 Binding of IFNG 27 0.48 14.31 2.45
119 INT41549 Positive_regulation of Localization of B2M 5 0.59 4.26 2.42
120 INT113339 Binding of JAK2 6 0.40 5.31 2.4
121 INT184063 Positive_regulation of Jak2 17 0.69 10.97 2.37
122 INT50006 Regulation of HLA-E 12 0.44 8.78 2.37
123 INT96070 Negative_regulation of PIAS1 3 0.35 1.08 2.23
124 INT34644 Binding of HLA-C 19 0.47 9.41 2.2
125 INT14854 Regulation of Gene_expression of HLA-DRB1 10 0.39 5.27 2.19
126 INT112784 Positive_regulation of Positive_regulation of IFNG 11 0.49 7.84 2.18
127 INT55469 Positive_regulation of Positive_regulation of PTAFR 9 0.47 3 2.17
128 INT118871 Negative_regulation of JAK2 15 0.57 11.4 2.16
129 INT91519 Negative_regulation of Positive_regulation of PTAFR 4 0.41 1.52 2.15
130 INT27878 Gene_expression of FCGR1B 22 0.26 20.62 2.04
131 INT118884 Gene_expression of IRF1 5 0.66 2.71 2
132 INT117545 Regulation of Gene_expression of HLA-A 2 0.33 2.3 1.99
133 INT107448 Positive_regulation of Jak2 8 0.50 5.33 1.98
134 INT57339 Negative_regulation of HLA-DRA 17 0.49 7.67 1.96
135 INT142461 Positive_regulation of Positive_regulation of Stat1 7 0.54 5.06 1.94
136 INT57431 Binding of PIAS1 4 0.30 4.35 1.94
137 INT85178 Gene_expression of OAS2 10 0.21 4.17 1.93
138 INT173116 Regulation of VCAM1 14 0.33 11.85 1.92
139 INT21782 Negative_regulation of B2M 11 0.46 5.49 1.92
140 INT155015 Positive_regulation of HLA-DOA 6 0.23 4.45 1.92
141 INT118882 Positive_regulation of Gene_expression of IRF1 1 0.49 1.35 1.92
142 INT100689 Negative_regulation of JAK1 8 0.57 5.36 1.87
143 INT61627 Transcription of IFNG 6 0.69 4.28 1.83
144 INT101013 Regulation of HLA-A 7 0.33 6.7 1.8
145 INT89639 Phosphorylation of CAMK2G 5 0.48 0.66 1.78
146 INT91430 Positive_regulation of CD44 25 0.69 15.43 1.76
147 INT94534 Gene_expression of MT2A 8 0.75 11.28 1.76
148 INT84548 Positive_regulation of HLA-DQA1 5 0.49 1.68 1.75
149 INT119837 Positive_regulation of Gene_expression of STAT1 6 0.49 3.66 1.73
150 INT138917 Positive_regulation of Gene_expression of Stat1 63 0.69 36.76 1.71
151 INT93004 Positive_regulation of Positive_regulation of VCAM1 3 0.47 2.93 1.66
152 INT82398 Binding of HLA-DMB 3 0.35 3.82 1.66
153 INT97062 Binding of PML 10 0.41 11.63 1.65
154 INT122951 Regulation of Binding of HLA-B 4 0.39 3.08 1.65
155 INT206144 Phosphorylation of JAK1 6 0.57 1.77 1.64
156 INT62430 Negative_regulation of HLA-A 5 0.32 4.3 1.63
157 INT113340 Phosphorylation of JAK2 17 0.78 5.69 1.6
158 INT99150 Localization of VCAM1 7 0.79 6.2 1.6
159 INT167692 Binding of NCAM1 11 0.36 6.73 1.59
160 INT186309 Binding of Stat1 18 0.48 5.31 1.58
161 INT140089 Positive_regulation of Stat1 5 0.68 3.42 1.58
162 INT8480 Gene_expression of PIAS1 3 0.78 1.73 1.57
163 INT78816 Positive_regulation of Positive_regulation of ICAM1 9 0.68 8.36 1.55
164 INT153409 Negative_regulation of Negative_regulation of Jak2 2 0.34 1.01 1.52
165 INT150156 Positive_regulation of Gene_expression of HLA-DOA 7 0.20 4.07 1.5
166 INT186064 Phosphorylation of STAT1 19 0.59 7.14 1.48
167 INT18503 Binding of SUMO1 7 0.27 6.21 1.48
168 INT189302 Positive_regulation of Gene_expression of HLA-DQA2 6 0.06 4.44 1.48
169 INT188397 Regulation of Positive_regulation of IRF6 4 0.12 1.34 1.47
170 INT131457 Gene_expression of FCGR1A 11 0.75 4.88 1.45
171 INT9784 Binding of B2M 9 0.47 6.18 1.44
172 INT93005 Positive_regulation of Binding of ICAM1 5 0.68 4.55 1.42
173 INT139326 Gene_expression of Stat1 6 0.76 2.49 1.41
174 INT121820 Binding of STAT1 9 0.46 2.54 1.4
175 INT65153 Binding of HLA-DPB1 5 0.34 3.29 1.4
176 INT271448 Regulation of HLA-DQB1 1 0.06 2.73 1.4
177 INT64952 Binding of HLA-DQA2 11 0.10 7.23 1.39
178 INT62824 Negative_regulation of Positive_regulation of ICAM1 7 0.53 2.94 1.39
179 INT63339 Transcription of ICAM1 6 0.69 3.92 1.37
180 INT134041 Phosphorylation of Jak2 6 0.75 3.71 1.37
181 INT6706 Phosphorylation of GBP1 3 0.59 0.37 1.37
182 INT95367 Negative_regulation of Positive_regulation of IRF6 7 0.21 3.5 1.34
183 INT89426 Binding of HLA-DRB3 2 0.41 1.77 1.32
184 INT69398 Regulation of Gene_expression of HLA-E 14 0.60 3.54 1.27
185 INT124943 Regulation of NCAM1 10 0.44 5.25 1.27
186 INT109243 Regulation of Positive_regulation of IFNG 1 0.45 1.27 1.23
187 INT119827 Gene_expression of PTPN11 31 0.75 24.21 1.22
188 INT74443 Positive_regulation of PML 11 0.53 12.52 1.21
189 INT100621 Localization of HLA-DRA 7 0.40 2.86 1.2
190 INT155846 Transcription of JAK1 4 0.67 1.93 1.19
191 INT119187 Gene_expression of HLA-DRB5 5 0.02 4.47 1.18
192 INT59024 Regulation of Regulation of B2M 2 0.03 0.31 1.17
193 INT37679 Positive_regulation of HLA-DRB4 12 0.34 11.93 1.16
194 INT121814 Regulation of STAT1 3 0.43 0.83 1.15
195 INT234422 Gene_expression of PML 14 0.75 15.93 1.14
196 INT179884 Gene_expression of SOCS3 10 0.67 16.57 1.14
197 INT58042 Binding of HLA-DQA1 8 0.24 5.03 1.14
198 INT91431 Positive_regulation of Gene_expression of CD44 18 0.69 9.25 1.12
199 INT178262 Transcription of Stat1 4 0.59 4.73 1.12
200 INT8482 Positive_regulation of PIAS1 2 0.40 0.73 1.12
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