GO:0060335

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Name positive regulation of interferon-gamma-mediated signaling pathway
Categary Process
Go Slim No
Go Link GO:0060335
Unique Molecular Interactions 54
Total Molecular Interactions 73
Total Single Events 301
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of interferon-gamma-mediated signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of interferon-gamma-mediated signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT192332 UBR7 Negative_regulation of TXK 1 0.00 1.38 0.63
2 INT169290 CNR1 Positive_regulation of Negative_regulation of TXK 1 0.10 0.18 0.58
3 INT156833 Binding of MED1 and TRPV6 1 0.32 0 0.15
4 INT156837 Binding of CYP24A1 and MED1 1 0.47 0 0.15
5 INT309904 Binding of ERBB2 and TXK 1 0.01 0.23 0.08
6 INT110856 TXK Negative_regulation of Egf 1 0.02 1.2 0.08
7 INT251777 Negative_regulation of TXK Positive_regulation of PDGFA 1 0.04 1 0.08
8 INT251773 TXK Positive_regulation of PDGFA 1 0.04 1 0.08
9 INT309903 Binding of EGF and TXK 1 0.03 0.23 0.08
10 INT279286 Binding of TXK and VEGFA 3 0.05 2.35 0.07
11 INT251776 Negative_regulation of TXK Negative_regulation of ERBB4 1 0.04 1.07 0.06
12 INT279275 PDGFA Positive_regulation of TXK 1 0.05 1.02 0.06
13 INT225490 Med1 Positive_regulation of Ppara 1 0.12 0.26 0.06
14 INT251774 Negative_regulation of TXK Negative_regulation of EGFR 1 0.07 1.06 0.06
15 INT279281 TXK Regulation of CDCP1 1 0.00 1.61 0.05
16 INT251778 Negative_regulation of TXK Positive_regulation of KDR 1 0.03 0.99 0.05
17 INT251779 TXK Positive_regulation of KDR 1 0.03 0.99 0.05
18 INT279284 TXK Regulation of KDR 3 0.05 2.22 0.04
19 INT292089 Binding of KIT and TXK 1 0.02 1.54 0.04
20 INT292084 Binding of FLT3 and TXK 1 0.02 1.53 0.04
21 INT292090 Negative_regulation of Binding of KIT and TXK 1 0.02 1.54 0.04
22 INT292083 Binding of KDR and TXK 1 0.04 1.52 0.04
23 INT292092 Binding of PDGFRB and TXK 1 0.05 1.53 0.04
24 INT292085 Negative_regulation of Binding of FLT3 and TXK 1 0.02 1.54 0.04
25 INT261393 Binding of Nsdhl and Med1 1 0.02 1 0.04
26 INT292094 Binding of FLT4 and TXK 1 0.02 1.53 0.04
27 INT292095 Negative_regulation of Binding of KDR and TXK 1 0.04 1.53 0.04
28 INT292080 Binding of FLT1 and TXK 1 0.04 1.47 0.04
29 INT292079 Negative_regulation of Binding of PDGFRB and TXK 1 0.06 1.54 0.04
30 INT292086 Negative_regulation of Binding of FLT1 and TXK 1 0.04 1.48 0.04
31 INT292093 Negative_regulation of Binding of FLT4 and TXK 1 0.03 1.53 0.04
32 INT279285 PDGFB Positive_regulation of TXK 1 0.05 0.52 0.03
33 INT208410 IGF1 Positive_regulation of TXK 1 0.08 0.9 0.03
34 INT351090 Phosphorylation of TXK Positive_regulation of EGFR 1 0.04 0.33 0
35 INT225585 Regulation of Binding of Med1 and Tpr 1 0.00 0.07 0
36 INT292680 Negative_regulation of TXK Negative_regulation of ABL1 1 0.00 0.26 0
37 INT223577 TXK Negative_regulation of EGFR 1 0.08 0.18 0
38 INT351602 TXK Positive_regulation of ERBB2 1 0.02 0.58 0
39 INT341631 EGFR Positive_regulation of TXK 1 0.05 0.42 0
40 INT177262 Binding of MED1 and SV2A 1 0.23 0 0
41 INT279289 TXK Regulation of SRC 1 0.04 0.68 0
42 INT351604 TXK Positive_regulation of EGFR 1 0.02 1.78 0
43 INT294095 Binding of TXK and Gtf3a 1 0.00 2.33 0
44 INT268599 Mir10a Regulation of TXK 1 0.01 1.09 0
45 INT225481 Binding of Med1 and Acp5 1 0.16 0 0
46 INT177286 Binding of CXADR and MED1 1 0.27 0 0
47 INT223583 TXK Negative_regulation of ERBB2 1 0.07 0.18 0
48 INT279283 TXK Regulation of PDGFRB 1 0.06 0.68 0
49 INT223581 TXK Negative_regulation of DBP 1 0.00 0.47 0
50 INT303947 Binding of LEPR and TXK 1 0.00 0.63 0
51 INT225541 Binding of Med1 and Tpr 1 0.00 0.07 0
52 INT177280 Binding of MED1 and FAUP1 1 0.01 0 0
53 INT351085 Binding of EGFR and Positive_regulation of Phosphorylation of TXK 1 0.04 0.35 0
54 INT294094 Binding of TXK and Eltd1 1 0.00 0.56 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of interferon-gamma-mediated signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of interferon-gamma-mediated signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT70134 Negative_regulation of TXK 124 0.23 81.96 9.59
2 INT118291 Binding of TXK 19 0.10 11.77 1.94
3 INT119520 Gene_expression of TXK 19 0.19 17.54 1.45
4 INT51264 Positive_regulation of TXK 21 0.54 10.69 1.1
5 INT119519 Positive_regulation of Gene_expression of TXK 3 0.09 2.92 1.02
6 INT142184 Regulation of TXK 10 0.11 8.25 0.59
7 INT171683 Negative_regulation of Negative_regulation of TXK 3 0.06 1.28 0.46
8 INT145045 Gene_expression of Med1 29 0.65 5.37 0.39
9 INT233917 Gene_expression of MED1 2 0.20 0.17 0.38
10 INT192343 Positive_regulation of Phosphorylation of TXK 4 0.06 1.42 0.37
11 INT192347 Phosphorylation of TXK 12 0.22 6.71 0.36
12 INT106734 Phosphorylation of MED1 4 0.74 1.65 0.28
13 INT279293 Localization of TXK 3 0.18 1.52 0.22
14 INT106730 Regulation of Phosphorylation of MED1 2 0.24 0.7 0.16
15 INT277845 Negative_regulation of Gene_expression of TXK 2 0.04 0.92 0.16
16 INT106731 Negative_regulation of Phosphorylation of MED1 1 0.02 0.96 0.12
17 INT156864 Positive_regulation of Phosphorylation of MED1 1 0.45 0 0.07
18 INT176589 Negative_regulation of Binding of TXK 6 0.09 2.06 0.05
19 INT279299 Positive_regulation of Localization of TXK 1 0.12 0.5 0.03
20 INT307189 Localization of Med1 3 0.53 0.32 0
21 INT225400 Positive_regulation of Gene_expression of Med1 2 0.35 0.82 0
22 INT225358 Negative_regulation of Gene_expression of Med1 2 0.30 1.16 0
23 INT177336 Positive_regulation of Binding of MED1 1 0.24 0 0
24 INT307197 Negative_regulation of Med1 1 0.30 0.7 0
25 INT307188 Transcription of Med1 1 0.48 0.7 0
26 INT266933 Regulation of Gene_expression of TXK 1 0.08 0.31 0
27 INT225389 Regulation of Binding of Med1 1 0.17 0.07 0
28 INT177320 Binding of MED1 1 0.25 0 0
29 INT225457 Binding of Med1 1 0.35 0.28 0
30 INT341851 Positive_regulation of MED1 1 0.01 0.5 0
31 INT266929 Positive_regulation of Negative_regulation of TXK 1 0.07 0.2 0
32 INT334482 Regulation of Gene_expression of Med1 1 0.17 0.1 0
33 INT279300 Negative_regulation of Phosphorylation of TXK 1 0.11 0.92 0
34 INT176568 Protein_catabolism of TXK 1 0.01 0.13 0
35 INT266930 Positive_regulation of Positive_regulation of TXK 1 0.12 0 0
36 INT334481 Negative_regulation of Localization of Med1 1 0.16 0.09 0
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