GO:0060351

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Name cartilage development involved in endochondral bone morphogenesis
Categary Process
Go Slim No
Go Link GO:0060351
Unique Molecular Interactions 157
Total Molecular Interactions 188
Total Single Events 1979
Pain Genes Associated 12

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cartilage development involved in endochondral bone morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported for cartilage development involved in endochondral bone morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69823 Binding of GHR and RYBP 1 0.01 0 3.23
2 INT261831 Mapk1 Negative_regulation of Hspg2 1 0.00 1.26 1.42
3 INT157460 CX3CL1 Regulation of Gene_expression of COL1A1 1 0.11 1.57 1.37
4 INT311914 Il1 Negative_regulation of Gene_expression of Col2a1 1 0.01 1.94 1.23
5 INT69824 Negative_regulation of Binding of GHR and RYBP 1 0.01 0 1.14
6 INT204551 Binding of Col2a1 and Positive_regulation of Cia1 1 0.03 1.74 1.03
7 INT222979 Negative_regulation of Binding of COL1A1 and FN1 1 0.01 1.64 0.93
8 INT45279 Binding of CSF2 and GHR 1 0.05 0.07 0.93
9 INT222978 Binding of COL1A1 and FN1 1 0.01 1.64 0.92
10 INT222988 TNF Positive_regulation of Protein_catabolism of COL1A1 1 0.01 1.66 0.9
11 INT166983 Binding of HLA-B and HSPG2 4 0.08 4.66 0.88
12 INT73775 Binding of GH1 and GHR 4 0.35 0.68 0.8
13 INT135781 Cyp3a23/3a1 Positive_regulation of Positive_regulation of Col1a1 1 0.01 0.78 0.8
14 INT73776 Regulation of Binding of GH1 and GHR 2 0.26 0.16 0.75
15 INT262580 Ngf Positive_regulation of Hspg2 1 0.03 0.35 0.72
16 INT261830 Hspg2 Negative_regulation of Trpa1 1 0.01 0.58 0.63
17 INT202043 MMP13 Regulation of Protein_catabolism of COL2A1 1 0.01 0.54 0.54
18 INT223934 HSPG2 Negative_regulation of Gene_expression of Cux1 1 0.03 0 0.53
19 INT235876 Hspg2 Positive_regulation of Prkca 1 0.03 0.23 0.53
20 INT192159 Mmp14 Regulation of Protein_catabolism of Col1a1 1 0.02 1.01 0.52
21 INT120384 PRKCD Positive_regulation of Localization of HSPG2 1 0.29 0.42 0.51
22 INT261498 CBS Positive_regulation of DSE 1 0.00 0 0.5
23 INT88889 Binding of HSPG2 and CALCRL 1 0.00 0 0.48
24 INT280189 Binding of Cbs and P2rx3 1 0.01 1.03 0.47
25 INT280188 Binding of Cbs and Trpv1 1 0.26 1.03 0.47
26 INT223936 HSPG2 Positive_regulation of Gene_expression of Cux1 1 0.03 0 0.46
27 INT223935 HSPG2 Positive_regulation of Cux1 1 0.03 0 0.45
28 INT343642 Adp Positive_regulation of Localization of Hspg2 1 0.01 0 0.44
29 INT343643 Adp Positive_regulation of Positive_regulation of Hspg2 1 0.01 0 0.43
30 INT312122 ELANE Positive_regulation of Protein_catabolism of COL2A1 1 0.05 0.65 0.39
31 INT261499 CBS Positive_regulation of CNR1 1 0.01 0.48 0.35
32 INT254344 Binding of Col2a1 and Ncoa5 1 0.00 0.98 0.35
33 INT149896 Ihh Regulation of Gene_expression of Col1a1 1 0.06 0.89 0.33
34 INT280190 Cbs Regulation of Gene_expression of Hist1h1t 1 0.04 0.58 0.32
35 INT350214 Binding of GPER and HSPG2 1 0.00 0.12 0.32
36 INT207631 Hspg2 Positive_regulation of Gene_expression of Prkca 1 0.03 0.08 0.31
37 INT264523 PTGDS Positive_regulation of Gene_expression of COL2A1 1 0.03 1.24 0.3
38 INT220194 PTGER2 Negative_regulation of COL2A1 1 0.26 0.55 0.29
39 INT328224 Col2a1 Positive_regulation of Gene_expression of Mmp13 1 0.04 0.8 0.29
40 INT137033 Tgfb1 Positive_regulation of Gene_expression of Col1a1 1 0.01 0.42 0.28
41 INT225101 TGFB1 Positive_regulation of Localization of COL1A1 1 0.03 0.59 0.28
42 INT137014 Positive_regulation of Pscs Positive_regulation of Gene_expression of Col1a1 1 0.01 0.42 0.28
43 INT225100 TGFB1 Positive_regulation of Gene_expression of COL1A1 1 0.04 0.59 0.28
44 INT137012 Pscs Positive_regulation of Gene_expression of Col1a1 1 0.01 0.42 0.28
45 INT271446 Thy1 Regulation of Col1a1 1 0.05 0.61 0.25
46 INT252784 ROS1 Positive_regulation of Gene_expression of COL1A1 1 0.05 1.86 0.24
47 INT308084 Binding of HSPG2 and OXT 1 0.04 0.25 0.23
48 INT62090 CXCR1 Positive_regulation of HSPG2 1 0.54 0.18 0.23
49 INT316810 Sparc Regulation of Col1a1 1 0.13 0.48 0.21
50 INT60347 COL2A1 Positive_regulation of Gene_expression of Hras 1 0.05 0.92 0.2
51 INT225099 ZNF630 Positive_regulation of Gene_expression of COL1A1 1 0.00 0.17 0.2
52 INT220190 PTGER2 Regulation of COL2A1 1 0.32 0.92 0.18
53 INT220191 Binding of COL2A1 and PTGER2 1 0.22 0.35 0.18
54 INT193562 Nr1i3 Positive_regulation of Hspg2 1 0.00 0 0.17
55 INT346305 Binding of ELANE and Col2a1 1 0.00 0.98 0.17
56 INT315491 Hspg2 Negative_regulation of Gene_expression of Il4 1 0.04 0.22 0.17
57 INT336337 Glp2r Positive_regulation of Gene_expression of Col2a1 1 0.01 0.7 0.14
58 INT293867 Binding of COL2A1 and MEFV 1 0.01 0.52 0.14
59 INT315492 Hspg2 Negative_regulation of Gene_expression of Il2 1 0.06 0.14 0.14
60 INT220213 Mmp13 Regulation of Protein_catabolism of COL2A1 1 0.49 0.29 0.14
61 INT157602 Binding of COL1A1 and COL3A1 1 0.04 0 0.13
62 INT248259 Binding of HSPG2 and Gtf3a 1 0.00 0.33 0.12
63 INT354620 AR Positive_regulation of Hspg2 1 0.00 0 0.12
64 INT316813 Sparc Negative_regulation of Gene_expression of Col1a1 1 0.13 0.67 0.12
65 INT326974 BMP2 Positive_regulation of Gene_expression of COL2A1 1 0.07 0.27 0.11
66 INT294445 KLK4 Negative_regulation of COL1A1 1 0.01 0 0.1
67 INT179869 COL1A1 Positive_regulation of SOCS3 1 0.04 0.99 0.1
68 INT324583 Hspg2 Positive_regulation of Trpm5 1 0.19 0 0.09
69 INT315490 Hspg2 Negative_regulation of Il2 1 0.08 0 0.09
70 INT25285 CBS Negative_regulation of Localization of IL1RL1 1 0.05 0 0.09
71 INT350220 Positive_regulation of HSPG2 Positive_regulation of Localization of ITPR3 1 0.05 0.09 0.09
72 INT220195 PTGER2 Negative_regulation of Localization of COL2A1 1 0.26 0.51 0.09
73 INT346304 Col2a1 Positive_regulation of Localization of PTGER2 1 0.00 0.18 0.09
74 INT350217 Positive_regulation of HSPG2 Positive_regulation of ITPR3 1 0.05 0.09 0.09
75 INT174104 Binding of HSPG2 and Ache 1 0.16 0.98 0.09
76 INT58630 Calca Negative_regulation of Positive_regulation of COL1A1 1 0.02 0.23 0.08
77 INT350218 Positive_regulation of HSPG2 Positive_regulation of Gene_expression of ITPR3 1 0.04 0.09 0.08
78 INT222983 TNF Positive_regulation of Positive_regulation of COL1A1 1 0.01 0.71 0.08
79 INT218710 MMP1 Regulation of Positive_regulation of Col1a1 1 0.00 0.15 0.07
80 INT288003 Binding of COL2A1 and PADI1 1 0.09 0.11 0.06
81 INT346302 ELANE Regulation of Col2a1 1 0.00 0.3 0.05
82 INT220537 HSPG2 Positive_regulation of NOSTRIN 1 0.04 0 0.05
83 INT180668 Edn1 Positive_regulation of Gene_expression of Col1a1 1 0.02 0 0.05
84 INT220081 Binding of COL1A1 and MMRN1 1 0.00 0.36 0.05
85 INT27738 CBS Positive_regulation of EGF 1 0.33 0.85 0.05
86 INT220189 Binding of COL2A1 and TIMP1 1 0.04 0.1 0.05
87 INT27737 CBS Positive_regulation of Positive_regulation of EGF 1 0.36 0.85 0.05
88 INT323807 NFAT5 Regulation of Gene_expression of COL2A1 1 0.29 0.19 0.04
89 INT275125 Binding of HLA-DOA and HSPG2 1 0.01 1.42 0.04
90 INT346303 Binding of MR1 and Col2a1 1 0.00 0.09 0.04
91 INT220196 Binding of PTGER2 and Negative_regulation of Gene_expression of COL2A1 1 0.26 0.77 0.04
92 INT275124 Binding of HSPG2 and LTA 1 0.12 1.45 0.04
93 INT322891 Sox9 Regulation of Transcription of Col2a1 1 0.10 0.12 0.04
94 INT222980 TNF Positive_regulation of Localization of COL1A1 1 0.01 0.56 0.04
95 INT199526 Ceacam1 Negative_regulation of Col1a1 1 0.01 0.06 0.03
96 INT233397 Binding of ABCA4 and COL2A1 1 0.38 3.59 0.03
97 INT220245 IL1RN Regulation of Protein_catabolism of COL2A1 1 0.09 0 0.03
98 INT222977 Positive_regulation of COL1A1 Positive_regulation of MMP1 1 0.01 0.61 0.03
99 INT222987 Positive_regulation of COL1A1 Positive_regulation of Protein_catabolism of MMP1 1 0.01 0.61 0.03
100 INT170329 Binding of Col4a1 and Col1a1 1 0.03 0.14 0.03
101 INT180565 HEYL Positive_regulation of Negative_regulation of COL1A1 1 0.01 0 0.03
102 INT180571 HEYL Positive_regulation of Protein_catabolism of COL1A1 1 0.01 0 0.03
103 INT265881 GHRH Positive_regulation of GHR 1 0.05 0.05 0.03
104 INT330484 Binding of Cxadr and Hspg2 1 0.18 0.52 0.03
105 INT170331 Binding of Col7a1 and Col1a1 1 0.00 0.14 0.03
106 INT249159 HSPG2 Positive_regulation of Gene_expression of ITPR3 2 0.01 0.06 0
107 INT252820 ELANE Positive_regulation of Gene_expression of COL1A1 1 0.01 0.58 0
108 INT312224 INPP5K Regulation of Negative_regulation of COL1A1 1 0.08 0 0
109 INT293869 Binding of COL2A1 and GREM1 1 0.00 1.11 0
110 INT352756 Hspg2 Negative_regulation of Sms 1 0.21 0.08 0
111 INT263900 Binding of Col1a1 and Cea 1 0.01 0.63 0
112 INT252796 ELANE Regulation of COL1A1 1 0.01 0.57 0
113 INT180847 Binding of COL1A1 and NID2 1 0.05 0.91 0
114 INT288002 Binding of COL2A1 and GOPC 1 0.12 0 0
115 INT173769 Dlat Regulation of Ghr 1 0.04 0 0
116 INT165506 HSPG2 Negative_regulation of Gene_expression of CYBB 1 0.03 0.06 0
117 INT256103 Serpina3k Negative_regulation of Positive_regulation of Hspg2 1 0.02 0.15 0
118 INT63391 SLTM Regulation of Gene_expression of Col2a1 1 0.00 0 0
119 INT312230 INPP5K Regulation of Gene_expression of COL2A1 1 0.06 0 0
120 INT312214 INPP5K Regulation of Gene_expression of COL1A1 1 0.08 0 0
121 INT165511 Binding of HSPG2 and NOSTRIN 1 0.02 0.07 0
122 INT252773 ROS1 Positive_regulation of COL1A1 1 0.05 0.57 0
123 INT147529 TGFB1 Negative_regulation of Gene_expression of Col2a1 1 0.05 0.32 0
124 INT343639 Grm1 Positive_regulation of Hspg2 1 0.00 0 0
125 INT88567 COL2A1 Positive_regulation of A1cf 1 0.09 0.36 0
126 INT252800 ROS1 Regulation of COL1A1 1 0.05 0.57 0
127 INT97091 HSPG2 Regulation of PRKCA 1 0.04 0 0
128 INT312227 INPP5K Regulation of Negative_regulation of COL2A1 1 0.06 0 0
129 INT252813 ELANE Positive_regulation of COL1A1 1 0.01 0.57 0
130 INT165510 HSPG2 Negative_regulation of Gene_expression of NFKB1 1 0.01 0.06 0
131 INT118660 Binding of COL1A1 and GAPDH 1 0.16 0.09 0
132 INT256104 Binding of Serpina3k and Positive_regulation of Positive_regulation of Hspg2 1 0.03 1 0
133 INT354789 Tnc Regulation of HSPG2 1 0.02 1.38 0
134 INT96782 FAM176C Regulation of Gene_expression of COL1A1 1 0.32 0.05 0
135 INT180859 Binding of COL1A1 and NID1 1 0.01 0.9 0
136 INT165863 Binding of HSPG2 and PTGS2 1 0.01 0.19 0
137 INT312345 Binding of COL2A1 and COL5A2 1 0.00 1.21 0
138 INT323804 NFAT5 Regulation of Transcription of COL2A1 1 0.43 0.07 0
139 INT252802 ROS1 Regulation of Gene_expression of COL1A1 1 0.05 0.58 0
140 INT252776 ELANE Regulation of Gene_expression of COL1A1 1 0.01 0.58 0
141 INT206621 Col1a1 Positive_regulation of Col3a1 1 0.00 0.28 0
142 INT165508 Binding of HSPG2 and VEGFA 1 0.01 0.07 0
143 INT312213 INPP5K Regulation of COL2A1 1 0.06 0 0
144 INT256105 Serpina3k Negative_regulation of Phosphorylation of Hspg2 1 0.02 0.2 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cartilage development involved in endochondral bone morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported in cartilage development involved in endochondral bone morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT11659 Gene_expression of COL2A1 164 0.78 78.49 22.58
2 INT17313 Positive_regulation of HSPG2 57 0.67 55.78 16.65
3 INT19963 Gene_expression of COL1A1 118 0.59 42.11 15.15
4 INT96924 Positive_regulation of Hspg2 40 0.49 14.5 12.32
5 INT37618 Gene_expression of Col2a1 50 0.70 33.88 11.58
6 INT54834 Gene_expression of Col2a1 48 0.72 13.5 9.41
7 INT130497 Gene_expression of Cbs 5 0.77 16.93 9.34
8 INT130731 Protein_catabolism of COL2A1 47 0.96 21.86 9.28
9 INT76860 Gene_expression of HSPG2 32 0.65 37.14 9.06
10 INT261511 Localization of CBS 1 0.02 5.06 7.27
11 INT75382 Negative_regulation of HSPG2 20 0.57 15.18 7.03
12 INT19086 Negative_regulation of COL1A1 32 0.38 16.77 5.98
13 INT9895 Binding of GHR 18 0.36 4.8 5.65
14 INT112883 Gene_expression of Hspg2 22 0.65 6.54 4.95
15 INT17312 Binding of HSPG2 30 0.41 33.01 4.88
16 INT20552 Negative_regulation of Gene_expression of COL2A1 29 0.56 11.92 4.81
17 INT69215 Gene_expression of Col1a1 38 0.68 17.39 4.77
18 INT115927 Negative_regulation of Hspg2 27 0.57 4.16 4.53
19 INT4283 Positive_regulation of Cbs 10 0.46 6.85 4.44
20 INT19965 Positive_regulation of COL1A1 23 0.45 14.49 4.38
21 INT107771 Localization of HSPG2 10 0.78 8.47 4.3
22 INT217742 Positive_regulation of Gene_expression of COL2A1 20 0.67 9.76 4.23
23 INT95512 Transcription of Ghr 24 0.69 3.1 4.12
24 INT124815 Binding of Col2a1 9 0.37 10.27 3.93
25 INT280193 Positive_regulation of Gene_expression of Cbs 1 0.69 6.59 3.81
26 INT47678 Positive_regulation of Positive_regulation of HSPG2 7 0.49 3.94 3.56
27 INT53021 Positive_regulation of COL2A1 29 0.55 27.75 3.47
28 INT130729 Negative_regulation of Protein_catabolism of COL2A1 15 0.42 7.59 3.35
29 INT81229 Binding of COL1A1 24 0.35 12.07 3.3
30 INT39867 Binding of Col2a1 9 0.35 7.65 3.18
31 INT54832 Negative_regulation of Gene_expression of Col2a1 6 0.50 2.53 3.16
32 INT67719 Positive_regulation of Col1a1 21 0.44 8.87 3.12
33 INT171884 Positive_regulation of Gene_expression of Col2a1 11 0.23 8.04 3.02
34 INT20551 Negative_regulation of COL2A1 31 0.55 21.98 2.66
35 INT96693 Binding of COL2A1 45 0.46 37.11 2.61
36 INT68091 Localization of COL1A1 19 0.66 9.13 2.56
37 INT8890 Transcription of Col1a1 10 0.63 4.02 2.48
38 INT79261 Positive_regulation of Gene_expression of COL1A1 24 0.36 7.49 2.45
39 INT22019 Regulation of GHR 9 0.62 2.56 2.39
40 INT16286 Positive_regulation of GHR 8 0.60 4.04 2.31
41 INT97152 Protein_catabolism of COL1A1 11 0.74 8.03 2.3
42 INT126513 Gene_expression of Col1a1 23 0.75 10.92 2.18
43 INT95510 Regulation of Ghr 1 0.45 0.21 2.07
44 INT113717 Negative_regulation of Gene_expression of COL1A1 21 0.41 6.14 2.01
45 INT4643 Negative_regulation of GHR 10 0.45 3.01 2
46 INT120857 Localization of Col1a1 10 0.71 2.33 1.93
47 INT120407 Positive_regulation of Localization of HSPG2 2 0.49 2.11 1.92
48 INT96116 Transcription of COL1A1 10 0.44 4.57 1.81
49 INT164407 Negative_regulation of Gene_expression of Col2a1 6 0.39 4 1.78
50 INT75316 Gene_expression of Ghr 6 0.78 1.24 1.68
51 INT248253 Positive_regulation of Gene_expression of HSPG2 3 0.44 4.61 1.65
52 INT220992 Protein_catabolism of Col2a1 8 0.40 5.55 1.64
53 INT164410 Negative_regulation of Col2a1 4 0.39 3.75 1.53
54 INT153201 Negative_regulation of Gene_expression of Col1a1 7 0.38 6.37 1.52
55 INT28300 Gene_expression of GHR 10 0.78 4.29 1.5
56 INT142719 Binding of Col1a1 7 0.34 5.83 1.47
57 INT32184 Negative_regulation of Col2a1 9 0.42 3.05 1.43
58 INT262545 Positive_regulation of Positive_regulation of Hspg2 4 0.49 1.39 1.41
59 INT159378 Localization of Hspg2 6 0.80 0.9 1.35
60 INT120860 Positive_regulation of Gene_expression of Col1a1 12 0.44 4.84 1.34
61 INT54831 Regulation of Gene_expression of Col2a1 4 0.39 2.3 1.31
62 INT117232 Localization of COL2A1 11 0.72 7.34 1.3
63 INT112650 Positive_regulation of Col1a1 3 0.30 5.96 1.3
64 INT34626 Binding of Cbs 2 0.37 3.27 1.27
65 INT128714 Transcription of Col2a1 6 0.52 2.13 1.24
66 INT59473 Negative_regulation of Col1a1 4 0.25 1.33 1.24
67 INT71845 Positive_regulation of Positive_regulation of Col1a1 1 0.34 0.15 1.23
68 INT144645 Localization of Cbs 2 0.64 1.02 1.22
69 INT140033 Positive_regulation of Gene_expression of Col1a1 6 0.14 3.68 1.2
70 INT176463 Protein_catabolism of Col2a1 4 0.35 1.94 1.2
71 INT95511 Negative_regulation of Transcription of Ghr 1 0.43 0 1.15
72 INT11658 Regulation of Gene_expression of COL2A1 9 0.62 3.09 1.11
73 INT61512 Regulation of Binding of GHR 2 0.05 0.89 1.1
74 INT54835 Regulation of Col2a1 5 0.59 2.08 1.07
75 INT120395 Regulation of HSPG2 4 0.26 5.96 1.03
76 INT4971 Regulation of Cbs 2 0.44 1.66 1
77 INT156614 Regulation of Gene_expression of COL1A1 6 0.33 2.51 0.99
78 INT95514 Negative_regulation of Ghr 3 0.36 1.3 0.99
79 INT168233 Positive_regulation of Transcription of Col2a1 2 0.45 1.78 0.99
80 INT129997 Protein_catabolism of Col1a1 5 0.96 3.43 0.96
81 INT261514 Positive_regulation of Localization of CBS 1 0.01 0.67 0.91
82 INT235828 Binding of Hspg2 4 0.25 2.24 0.89
83 INT202190 Gene_expression of CBS 7 0.32 4.19 0.88
84 INT8888 Regulation of Col1a1 4 0.13 1.97 0.86
85 INT168089 Regulation of Localization of HSPG2 2 0.20 0.86 0.81
86 INT192156 Negative_regulation of Col1a1 6 0.39 3.92 0.8
87 INT173506 Positive_regulation of Col2a1 4 0.20 3.42 0.76
88 INT280194 Regulation of Gene_expression of Cbs 1 0.61 1.54 0.73
89 INT37617 Regulation of Gene_expression of Col2a1 3 0.31 1.48 0.7
90 INT73783 Regulation of Gene_expression of GHR 1 0.45 0 0.7
91 INT272706 Negative_regulation of Localization of Hspg2 2 0.18 0 0.68
92 INT89520 Regulation of COL1A1 8 0.32 3.21 0.66
93 INT261508 Negative_regulation of CBS 1 0.01 0.39 0.61
94 INT63389 Localization of Col2a1 7 0.68 1.95 0.6
95 INT95508 Negative_regulation of Gene_expression of Ghr 1 0.59 0 0.56
96 INT125583 Regulation of Positive_regulation of HSPG2 2 0.44 0.1 0.54
97 INT68092 Negative_regulation of Localization of COL1A1 1 0.48 0 0.53
98 INT354787 Regulation of Binding of HSPG2 1 0.23 1.63 0.53
99 INT235835 Negative_regulation of Gene_expression of Hspg2 3 0.15 1.26 0.52
100 INT8886 Regulation of Transcription of Col1a1 1 0.04 0 0.5
101 INT32183 Positive_regulation of Negative_regulation of Col2a1 2 0.46 1.01 0.49
102 INT75381 Positive_regulation of Negative_regulation of HSPG2 2 0.49 0.09 0.46
103 INT125840 Positive_regulation of Binding of Col2a1 1 0.43 1.21 0.45
104 INT9732 Regulation of COL2A1 9 0.58 6.93 0.44
105 INT343622 Positive_regulation of Localization of Hspg2 1 0.08 0 0.43
106 INT173752 Positive_regulation of Ghr 3 0.57 2.21 0.41
107 INT261515 Positive_regulation of CBS 2 0.47 2.63 0.41
108 INT300893 Protein_catabolism of HSPG2 1 0.27 1.1 0.41
109 INT320812 Positive_regulation of Localization of COL1A1 1 0.05 1.04 0.4
110 INT82331 Positive_regulation of Positive_regulation of GHR 1 0.00 0.06 0.4
111 INT223932 Regulation of Negative_regulation of HSPG2 1 0.03 0.06 0.38
112 INT98870 Negative_regulation of Positive_regulation of HSPG2 2 0.41 0 0.37
113 INT111345 Negative_regulation of Cbs 2 0.30 2.82 0.36
114 INT28299 Negative_regulation of Gene_expression of GHR 1 0.03 0.1 0.35
115 INT259859 Regulation of CBS 1 0.01 1.26 0.34
116 INT163709 Regulation of Negative_regulation of COL1A1 1 0.29 0.93 0.34
117 INT182549 Regulation of Positive_regulation of Hspg2 1 0.07 0.2 0.34
118 INT54833 Positive_regulation of Col2a1 5 0.52 1.1 0.32
119 INT180577 Positive_regulation of Protein_catabolism of COL2A1 2 0.12 0.91 0.31
120 INT254811 Localization of Col1a1 3 0.29 1.39 0.3
121 INT88899 Positive_regulation of Binding of HSPG2 1 0.01 0 0.3
122 INT291615 Negative_regulation of Localization of Col1a1 1 0.06 1.28 0.3
123 INT269370 Negative_regulation of Gene_expression of HSPG2 2 0.07 0.93 0.29
124 INT220209 Negative_regulation of Localization of COL2A1 1 0.41 0.48 0.29
125 INT126512 Negative_regulation of Gene_expression of Col1a1 3 0.39 2.2 0.27
126 INT259857 Regulation of Gene_expression of CBS 1 0.01 1.07 0.27
127 INT176464 Protein_catabolism of Col1a1 1 0.19 0.83 0.26
128 INT181524 Negative_regulation of Binding of Col2a1 1 0.13 1.05 0.25
129 INT271432 Positive_regulation of Regulation of Col1a1 1 0.10 0.61 0.24
130 INT76857 Transcription of HSPG2 6 0.60 5.07 0.23
131 INT225109 Regulation of Localization of COL1A1 1 0.05 0.41 0.23
132 INT275310 Positive_regulation of Protein_catabolism of Col2a1 1 0.16 0.88 0.22
133 INT218694 Binding of Col1a1 2 0.21 1.52 0.21
134 INT120859 Positive_regulation of Localization of Col1a1 1 0.16 0.05 0.18
135 INT187816 Positive_regulation of Transcription of Col1a1 1 0.06 0.82 0.17
136 INT220208 Regulation of Protein_catabolism of COL2A1 1 0.26 0.28 0.17
137 INT63646 Localization of Col2a1 3 0.77 0.37 0.16
138 INT130000 Positive_regulation of Protein_catabolism of Col1a1 1 0.49 1.15 0.15
139 INT187815 Transcription of Col1a1 1 0.09 0.76 0.15
140 INT73297 Positive_regulation of Transcription of Col1a1 2 0.32 3.12 0.14
141 INT259858 Protein_catabolism of CBS 1 0.03 1.46 0.14
142 INT220367 Regulation of Positive_regulation of Ghr 1 0.44 0.45 0.14
143 INT22020 Regulation of Positive_regulation of GHR 1 0.39 1.03 0.14
144 INT257290 Negative_regulation of Transcription of COL1A1 3 0.27 1.64 0.13
145 INT95278 Positive_regulation of Gene_expression of Col2a1 2 0.47 0.21 0.13
146 INT221000 Phosphorylation of COL2A1 1 0.19 0.18 0.12
147 INT203079 Regulation of Transcription of Col2a1 1 0.05 0.07 0.11
148 INT173756 Positive_regulation of Transcription of Ghr 3 0.36 0.83 0.09
149 INT173340 Phosphorylation of HSPG2 2 0.08 0 0.09
150 INT346288 Phosphorylation of Col2a1 1 0.02 0.73 0.08
151 INT231709 Negative_regulation of Negative_regulation of Col2a1 1 0.27 0.18 0.06
152 INT339669 Regulation of Col2a1 1 0.01 1.02 0.05
153 INT250505 Positive_regulation of Negative_regulation of COL2A1 1 0.41 0.57 0.05
154 INT179886 Negative_regulation of Negative_regulation of COL1A1 1 0.05 0.5 0.05
155 INT272249 Negative_regulation of Negative_regulation of COL2A1 1 0.06 0 0.05
156 INT256069 Phosphorylation of Hspg2 1 0.03 3.46 0.05
157 INT184168 Localization of GHR 1 0.08 0.34 0.05
158 INT201964 Transcription of Col2a1 2 0.38 0.55 0.04
159 INT346287 Regulation of Binding of Col2a1 1 0.01 0.07 0.04
160 INT248258 Regulation of Gene_expression of HSPG2 1 0.13 0.19 0.04
161 INT180589 Phosphorylation of COL1A1 3 0.34 0.37 0.03
162 INT222999 Positive_regulation of Positive_regulation of COL1A1 1 0.04 0.61 0.03
163 INT324579 Negative_regulation of Negative_regulation of Hspg2 1 0.18 0 0.03
164 INT180582 Negative_regulation of Phosphorylation of COL1A1 1 0.07 0 0.03
165 INT180579 Negative_regulation of Protein_catabolism of COL1A1 1 0.07 0 0.03
166 INT250026 Regulation of Hspg2 1 0.05 0.16 0.03
167 INT184729 Transcription of COL2A1 4 0.67 1.1 0
168 INT206617 Regulation of Gene_expression of Col1a1 2 0.06 0.49 0
169 INT165862 Positive_regulation of Binding of COL2A1 2 0.43 0 0
170 INT257285 Positive_regulation of Transcription of COL1A1 2 0.29 1.23 0
171 INT312246 Regulation of Negative_regulation of COL2A1 1 0.07 0 0
172 INT245725 Positive_regulation of Negative_regulation of Col1a1 1 0.21 0.7 0
173 INT256067 Negative_regulation of Phosphorylation of Hspg2 1 0.02 0.16 0
174 INT319565 Positive_regulation of Gene_expression of GHR 1 0.25 0.4 0
175 INT173755 Binding of Ghr 1 0.14 0 0
176 INT181205 Negative_regulation of Binding of GHR 1 0.07 0.2 0
177 INT252761 Positive_regulation of Regulation of COL1A1 1 0.08 0.17 0
178 INT176462 Positive_regulation of Protein_catabolism of Col2a1 1 0.16 0.21 0
179 INT249232 Regulation of Phosphorylation of HSPG2 1 0.03 0 0
180 INT75317 Regulation of Gene_expression of Ghr 1 0.03 0.26 0
181 INT349649 Negative_regulation of Localization of Col1a1 1 0.04 0 0
182 INT264310 Regulation of Col1a1 1 0.19 0 0
183 INT264309 Regulation of Localization of Col2a1 1 0.26 0 0
184 INT277704 Regulation of Regulation of COL1A1 1 0.08 0.61 0
185 INT256070 Positive_regulation of Phosphorylation of Hspg2 1 0.02 1.26 0
186 INT209434 Negative_regulation of Protein_catabolism of Col1a1 1 0.10 0 0
187 INT256068 Negative_regulation of Positive_regulation of Hspg2 1 0.02 1.38 0
188 INT322897 Negative_regulation of Transcription of COL2A1 1 0.17 0 0
189 INT63388 Positive_regulation of Localization of Col2a1 1 0.01 0.16 0
190 INT254803 Positive_regulation of Localization of Col1a1 1 0.10 0.11 0
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