GO:0060363

From wiki-pain
Jump to: navigation, search
Name cranial suture morphogenesis
Categary Process
Go Slim No
Go Link GO:0060363
Unique Molecular Interactions 86
Total Molecular Interactions 108
Total Single Events 948
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cranial suture morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported for cranial suture morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT48881 TWIST1 Positive_regulation of Localization of Abat 1 0.02 0.44 1.29
2 INT275097 Twist1 Regulation of Ltp 1 0.01 0.37 0.96
3 INT142709 Binding of TWIST1 and CEBPZ 2 0.17 1.16 0.95
4 INT243626 Twist1 Regulation of Hand1 1 0.15 1.55 0.72
5 INT243639 Twist1 Negative_regulation of Gene_expression of Il2 1 0.24 1.28 0.65
6 INT102864 Prkaca Regulation of Twist1 1 0.48 0.05 0.58
7 INT102364 BRD1 Positive_regulation of Twist1 1 0.00 0 0.47
8 INT117531 Twist1 Regulation of CSAD 1 0.00 0.85 0.47
9 INT102862 Prkaca Regulation of Phosphorylation of Twist1 1 0.19 0.1 0.42
10 INT152158 NENF Regulation of TWIST1 1 0.01 0.33 0.4
11 INT243627 Twist1 Regulation of Gene_expression of Ik 1 0.01 0.13 0.34
12 INT243622 Twist1 Regulation of Jak2 1 0.30 0.2 0.32
13 INT243641 Twist1 Positive_regulation of Socs1 1 0.14 0.13 0.31
14 INT243634 Twist1 Regulation of Socs1 1 0.14 0.13 0.31
15 INT243625 Stat4 Positive_regulation of Gene_expression of Twist1 1 0.39 0.75 0.3
16 INT243630 Il12a Positive_regulation of Gene_expression of Twist1 1 0.18 0.69 0.3
17 INT275092 Twist1 Regulation of stm 1 0.00 0 0.25
18 INT243640 Binding of Twist1 and Stub1 1 0.08 0.34 0.24
19 INT235125 PDE2A Negative_regulation of Twist1 1 0.00 0.99 0.24
20 INT115148 PPARG Negative_regulation of Gene_expression of INSIG2 1 0.01 0.34 0.21
21 INT209581 Twist1 Positive_regulation of Gene_expression of VEGFA 6 0.06 7.86 0.16
22 INT219601 Pde4a Negative_regulation of Twist1 1 0.10 0 0.16
23 INT219598 Pde4a Negative_regulation of Gene_expression of Twist1 1 0.10 0 0.16
24 INT208458 TWIST1 Positive_regulation of Localization of Bdnf 1 0.01 0.19 0.15
25 INT301414 Binding of Enpp2 and Twist1 1 0.08 1.26 0.13
26 INT262197 Nr1i2 Positive_regulation of Insig1 2 0.23 0 0.12
27 INT243642 Binding of Nfatc1 and Twist1 1 0.08 0.23 0.12
28 INT281192 Casr Positive_regulation of Insig1 1 0.23 0 0.12
29 INT302287 Twist1 Positive_regulation of Positive_regulation of PTGER2 1 0.03 1.16 0.1
30 INT302288 Twist1 Positive_regulation of PTGER2 1 0.03 1.16 0.1
31 INT340505 Binding of Twist1 and Mgat4b 1 0.01 0.45 0.08
32 INT350909 Binding of Pcsk4 and Twist1 1 0.02 1.91 0.08
33 INT350908 Binding of Bcl2 and Twist1 1 0.04 1.9 0.08
34 INT273372 IL6 Regulation of Regulation of TWIST1 1 0.10 0.1 0.07
35 INT273366 IL6 Regulation of TWIST1 1 0.06 0.1 0.07
36 INT84751 Binding of HRAS and TWIST1 1 0.29 2.6 0.07
37 INT335129 PPARA Positive_regulation of Gene_expression of Insig1 1 0.20 0.15 0.07
38 INT349886 Negative_regulation of Binding of Pcyt1a and Twist1 1 0.02 1.21 0.06
39 INT243637 Il12a Positive_regulation of Transcription of Twist1 1 0.18 0.12 0.06
40 INT349887 Binding of Pcyt1a and Twist1 1 0.02 1.21 0.06
41 INT282552 POU5F1 Positive_regulation of FGF4 1 0.29 0.29 0.05
42 INT287223 Pdx1 Regulation of Transcription of Insig1 1 0.03 0.56 0.05
43 INT287222 Cytip Regulation of Transcription of Insig1 1 0.02 0.56 0.05
44 INT273353 Pde4d Regulation of Gene_expression of Twist1 1 0.26 0.25 0.05
45 INT243633 Il23a Positive_regulation of Gene_expression of Twist1 1 0.14 0.11 0.05
46 INT210261 Bmp4 Regulation of Gene_expression of Tff3 1 0.64 0 0.05
47 INT287221 Tcf3 Regulation of Transcription of Insig1 1 0.03 0.56 0.05
48 INT233849 Twist1 Positive_regulation of Snai2 1 0.07 0.58 0.04
49 INT233852 Twist1 Positive_regulation of Snai1 1 0.02 0.58 0.04
50 INT275090 Twist1 Positive_regulation of Gene_expression of Pde5a 1 0.02 0.62 0.04
51 INT233851 Twist1 Positive_regulation of Zeb1 1 0.06 0.58 0.04
52 INT275095 Twist1 Positive_regulation of Pde5a 1 0.03 0.62 0.04
53 INT233854 Twist1 Positive_regulation of Itk 1 0.03 0.58 0.04
54 INT243636 Stat1 Positive_regulation of Gene_expression of Twist1 1 0.46 0.05 0.03
55 INT301413 Positive_regulation of Binding of Enpp2 and Twist1 1 0.11 0.18 0.03
56 INT301415 Positive_regulation of Binding of Twist1 and IL19 1 0.11 0.18 0.03
57 INT301416 Binding of Twist1 and IL19 1 0.08 0.18 0.03
58 INT301408 Positive_regulation of Binding of Enpp1 and Twist1 1 0.06 0.18 0.03
59 INT301406 Binding of Enpp1 and Twist1 1 0.04 0.18 0.03
60 INT235800 Twist1 Positive_regulation of VEGFA 1 0.02 0.62 0.03
61 INT209580 Twist1 Positive_regulation of Localization of VEGFA 1 0.05 0.53 0
62 INT280164 Twist1 Negative_regulation of Mod2 1 0.06 1.76 0
63 INT262212 Positive_regulation of Nr1i2 Positive_regulation of Insig1 1 0.12 0 0
64 INT273770 VEGFA Negative_regulation of Localization of Twist1 1 0.07 0.58 0
65 INT350906 Twist1 Positive_regulation of Gene_expression of Cd4 1 0.10 1.49 0
66 INT286988 Twist1 Positive_regulation of EGFR 1 0.17 2.01 0
67 INT331700 Fgf4 Positive_regulation of Gene_expression of Mmp9 1 0.30 0.41 0
68 INT196023 Bmp2 Negative_regulation of Gene_expression of Bmp4 1 0.09 0.07 0
69 INT275091 Negative_regulation of Twist1 Positive_regulation of Pde5a 1 0.02 0.06 0
70 INT121479 Twist1 Negative_regulation of Ins1 1 0.10 0 0
71 INT196021 Bmp2 Positive_regulation of Gene_expression of Bmp4 1 0.09 0.08 0
72 INT286188 Twist1 Positive_regulation of Serpina5 1 0.02 0 0
73 INT350907 Twist1 Positive_regulation of Gene_expression of Cd7 1 0.05 1.49 0
74 INT280166 Binding of MAPK8 and Twist1 1 0.19 0.78 0
75 INT243623 Il12a Positive_regulation of Twist1 1 0.17 0 0
76 INT243624 Stat6 Negative_regulation of Gene_expression of Twist1 1 0.30 0 0
77 INT6131 INSIG1 Positive_regulation of POMC 1 0.06 0.61 0
78 INT196022 Bmp7 Regulation of Bmp4 1 0.06 0.06 0
79 INT280167 Twist1 Positive_regulation of MAPK8 1 0.29 0.94 0
80 INT280163 Twist1 Positive_regulation of Mod2 1 0.07 1.67 0
81 INT326726 Twist1 Regulation of Itk 1 0.02 0.84 0
82 INT260529 Twist1 Positive_regulation of Gene_expression of Vegfa 1 0.04 0.54 0
83 INT331701 Fgf4 Positive_regulation of Gene_expression of Kdr 1 0.11 0.54 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cranial suture morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported in cranial suture morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT79395 Gene_expression of Twist1 193 0.77 100.06 26.34
2 INT10874 Negative_regulation of Twist1 89 0.50 36.84 11.32
3 INT43820 Positive_regulation of Twist1 75 0.59 42.15 8.47
4 INT136664 Positive_regulation of Gene_expression of Twist1 49 0.69 25.91 5.41
5 INT94028 Regulation of Twist1 37 0.44 22.41 5.33
6 INT64766 Gene_expression of TWIST1 41 0.76 37.89 3.4
7 INT116540 Binding of Twist1 35 0.48 16.32 2.85
8 INT48880 Positive_regulation of TWIST1 15 0.59 8.6 1.98
9 INT102861 Phosphorylation of Twist1 6 0.70 0.86 1.81
10 INT120088 Gene_expression of Bmp4 37 0.73 13.89 1.73
11 INT101707 Gene_expression of FGF4 9 0.78 3.99 1.73
12 INT180238 Regulation of Gene_expression of Twist1 13 0.61 4.87 1.59
13 INT270631 Gene_expression of Insig1 15 0.32 5.19 1.43
14 INT102860 Positive_regulation of Phosphorylation of Twist1 1 0.35 0.15 1.42
15 INT10873 Localization of Twist1 21 0.74 10.43 1.37
16 INT219579 Negative_regulation of Gene_expression of Twist1 12 0.43 9.07 1.36
17 INT243621 Transcription of Twist1 13 0.71 4.08 1.23
18 INT141475 Negative_regulation of Gene_expression of TWIST1 5 0.41 3.94 0.97
19 INT142122 Regulation of Gene_expression of Bmp4 5 0.43 2.69 0.86
20 INT210247 Positive_regulation of Bmp4 6 0.65 4.36 0.8
21 INT96422 Gene_expression of Bmp4 18 0.69 3.26 0.63
22 INT243616 Positive_regulation of Transcription of Twist1 6 0.69 2.09 0.6
23 INT62104 Localization of INSIG2 1 0.01 0 0.5
24 INT140436 Binding of TWIST1 5 0.39 2.34 0.47
25 INT142124 Binding of Bmp4 1 0.35 0.46 0.45
26 INT180688 Transcription of Bmp4 3 0.58 0.35 0.41
27 INT180702 Positive_regulation of Transcription of Bmp4 3 0.42 0.35 0.41
28 INT231199 Positive_regulation of Localization of Twist1 3 0.50 1.45 0.38
29 INT281177 Regulation of Insig1 2 0.25 0.93 0.33
30 INT114473 Regulation of Gene_expression of FGF4 1 0.45 0.81 0.32
31 INT297865 Positive_regulation of Gene_expression of Insig1 2 0.21 0.4 0.28
32 INT114474 Binding of FGF4 1 0.32 0.66 0.28
33 INT121475 Regulation of Negative_regulation of Twist1 3 0.14 2.43 0.24
34 INT262077 Positive_regulation of Insig1 3 0.29 0.34 0.21
35 INT142121 Positive_regulation of Gene_expression of Bmp4 3 0.47 7 0.21
36 INT270625 Regulation of Gene_expression of Insig1 2 0.19 1.4 0.21
37 INT297868 Regulation of Regulation of Insig1 1 0.11 0.82 0.21
38 INT115158 Gene_expression of INSIG2 1 0.01 0.33 0.21
39 INT120085 Negative_regulation of Gene_expression of Bmp4 5 0.55 0.61 0.17
40 INT135054 Negative_regulation of Negative_regulation of Twist1 2 0.42 0.46 0.17
41 INT295673 Regulation of FGF4 1 0.05 0.83 0.17
42 INT102354 Localization of TWIST1 3 0.75 0.17 0.15
43 INT186632 Regulation of TWIST1 4 0.37 5.28 0.14
44 INT273333 Negative_regulation of Regulation of Twist1 1 0.18 0.3 0.12
45 INT196033 Negative_regulation of Gene_expression of Bmp4 3 0.21 0.45 0.09
46 INT210243 Negative_regulation of Bmp4 1 0.55 0.55 0.07
47 INT287201 Transcription of Insig1 2 0.29 2.87 0.05
48 INT350900 Protein_catabolism of Twist1 1 0.22 0.78 0.05
49 INT196030 Positive_regulation of Bmp4 6 0.62 2.55 0.04
50 INT273406 Positive_regulation of Gene_expression of TWIST1 4 0.57 8.42 0.04
51 INT141476 Regulation of Gene_expression of TWIST1 2 0.50 2.57 0.04
52 INT210238 Positive_regulation of Negative_regulation of Bmp4 1 0.47 0 0.04
53 INT253182 Positive_regulation of Positive_regulation of Bmp4 1 0.45 0.58 0.04
54 INT282588 Positive_regulation of Gene_expression of FGF4 1 0.30 0.25 0.04
55 INT331697 Gene_expression of Fgf4 6 0.58 1.57 0
56 INT196034 Positive_regulation of Gene_expression of Bmp4 4 0.45 0.63 0
57 INT260779 Negative_regulation of Bmp4 4 0.23 0.94 0
58 INT149440 Negative_regulation of TWIST1 4 0.41 1.5 0
59 INT263106 Positive_regulation of Binding of Twist1 3 0.35 1.21 0
60 INT280152 Positive_regulation of Positive_regulation of Twist1 3 0.43 1.95 0
61 INT196027 Binding of Bmp4 2 0.13 0.97 0
62 INT142119 Regulation of Bmp4 2 0.58 0.29 0
63 INT331699 Positive_regulation of Fgf4 2 0.45 0.69 0
64 INT304047 Positive_regulation of Transcription of TWIST1 1 0.10 0.57 0
65 INT338245 Positive_regulation of Positive_regulation of TWIST1 1 0.38 2.95 0
66 INT280151 Positive_regulation of Regulation of Twist1 1 0.41 0.67 0
67 INT349880 Regulation of Binding of Twist1 1 0.31 0.98 0
68 INT331696 Localization of Fgf4 1 0.68 1.38 0
69 INT339667 Localization of Bmp4 1 0.38 0.27 0
70 INT349873 Regulation of Regulation of Twist1 1 0.31 0.97 0
71 INT262064 Negative_regulation of Positive_regulation of Insig1 1 0.09 0.05 0
72 INT275080 Positive_regulation of Negative_regulation of Twist1 1 0.05 0.11 0
73 INT335001 Positive_regulation of Gene_expression of Fgf4 1 0.13 0 0
74 INT243609 Negative_regulation of Transcription of Twist1 1 0.42 0 0
75 INT243602 Regulation of Localization of Twist1 1 0.45 0 0
76 INT297864 Positive_regulation of Transcription of Insig1 1 0.21 2.31 0
77 INT273393 Phosphorylation of TWIST1 1 0.16 0.4 0
78 INT286717 Regulation of Fgf4 1 0.26 0 0
79 INT6132 Regulation of INSIG1 1 0.03 1.23 0
80 INT304055 Transcription of TWIST1 1 0.14 0.57 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox