GO:0060374

From wiki-pain
Jump to: navigation, search
Name mast cell differentiation
Categary Process
Go Slim No
Go Link GO:0060374
Unique Molecular Interactions 51
Total Molecular Interactions 69
Total Single Events 569
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for mast cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported for mast cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT237154 LGALS4 Positive_regulation of KIT 1 0.10 1.99 0.47
2 INT337326 PIK3CD Positive_regulation of Localization of ITPR3 1 0.02 0 0.43
3 INT337325 PIK3CD Positive_regulation of Phosphorylation of IL2RG 1 0.00 0 0.43
4 INT337324 PIK3CD Positive_regulation of Gene_expression of ITPR3 1 0.02 0 0.43
5 INT237201 Cd3e Positive_regulation of KIT 1 0.03 0 0.21
6 INT298196 EGFR Positive_regulation of PIK3CD 1 0.04 0.65 0.18
7 INT249962 Binding of KIT and KITLG 6 0.19 3.69 0.17
8 INT194829 Gata3 Positive_regulation of IL13 1 0.01 0.12 0.15
9 INT194835 Gata3 Positive_regulation of IL5 1 0.01 0.12 0.15
10 INT194833 Binding of IL5 and Gata3 1 0.01 0.12 0.15
11 INT194827 Binding of IL13 and Gata3 1 0.01 0.12 0.15
12 INT139538 Binding of CD34 and KIT 2 0.39 2.73 0.14
13 INT338428 Il4 Positive_regulation of Gata3 1 0.06 0.75 0.13
14 INT335460 FPR1 Positive_regulation of PIK3CD 1 0.17 0 0.13
15 INT328435 PIK3CD Positive_regulation of Gene_expression of VEGFA 1 0.23 0.64 0.09
16 INT244640 AGK Negative_regulation of KIT 1 0.00 0.69 0.08
17 INT348168 Thbs1 Positive_regulation of PIK3CD 1 0.00 0.65 0.07
18 INT237197 KIT Positive_regulation of LPT 1 0.00 0.15 0.06
19 INT302164 PTEN Regulation of PIK3CD 1 0.16 1.13 0.06
20 INT328438 PRB4 Negative_regulation of PIK3CD 1 0.06 0.29 0.05
21 INT292089 Binding of KIT and TXK 1 0.02 1.54 0.04
22 INT292090 Negative_regulation of Binding of KIT and TXK 1 0.02 1.54 0.04
23 INT337727 ADAMTS2 Positive_regulation of Gene_expression of KIT 1 0.02 0 0.03
24 INT332286 PIK3CD Positive_regulation of MTOR 1 0.14 0.73 0.03
25 INT328436 PRB4 Negative_regulation of Gene_expression of PIK3CD 1 0.07 0.24 0.03
26 INT328430 PRB4 Regulation of Positive_regulation of PIK3CD 1 0.06 0.4 0.03
27 INT332284 IRS1 Regulation of PIK3CD 1 0.15 0.72 0.03
28 INT321402 Binding of NPHS1 and PIK3CD 1 0.02 0.73 0.03
29 INT332288 Positive_regulation of IRS1 Regulation of PIK3CD 1 0.07 0.73 0.03
30 INT322849 Binding of PIK3CD and PDCD10 1 0.16 0 0
31 INT234612 Binding of KIT and STIP1 1 0.04 1 0
32 INT328431 PIK3CD Negative_regulation of Gene_expression of VEGFA 1 0.22 0.29 0
33 INT186999 Binding of KIT and Gtf3a 1 0.00 0.25 0
34 INT217136 Negative_regulation of MIR221 Negative_regulation of Gene_expression of KIT 1 0.18 0.74 0
35 INT322844 Binding of KDR and PIK3CD 1 0.04 0 0
36 INT320712 Binding of NRAS and PIK3CD 1 0.21 1.66 0
37 INT192956 Binding of CD2 and KIT 1 0.03 0.62 0
38 INT192955 Binding of KIT and VCAM1 1 0.05 0.63 0
39 INT280546 Binding of KIT and TP63 1 0.01 1.19 0
40 INT328427 PIK3CD Negative_regulation of Phosphorylation of AKT1 1 0.09 0.29 0
41 INT322848 VEGFA Positive_regulation of PIK3CD 1 0.09 0 0
42 INT322843 Positive_regulation of PIK3CD Positive_regulation of Positive_regulation of RHOA 1 0.03 0 0
43 INT320715 NRAS Positive_regulation of PIK3CD 1 0.27 1.66 0
44 INT217138 Negative_regulation of MIR222 Negative_regulation of Gene_expression of KIT 1 0.16 0.74 0
45 INT237153 LGALS4 Regulation of KIT 1 0.09 0 0
46 INT150180 KIT Negative_regulation of Gene_expression of HLA-B 1 0.39 0.09 0
47 INT337732 KITLG Positive_regulation of KIT 1 0.03 0 0
48 INT295426 Binding of KIT and PDGFRB 1 0.24 0.4 0
49 INT312379 KIT Positive_regulation of Positive_regulation of Kit 1 0.01 1.37 0
50 INT337731 Binding of KIT and ADAMTS2 1 0.01 0.12 0
51 INT211882 Binding of KIT and CDCP1 1 0.00 2.1 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for mast cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported in mast cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69264 Gene_expression of KIT 207 0.78 179.41 8.95
2 INT120401 Positive_regulation of PIK3CD 33 0.45 14.89 7.37
3 INT116011 Positive_regulation of Gata3 5 0.31 3.17 4.21
4 INT110343 Negative_regulation of PIK3CD 22 0.40 5.84 4.2
5 INT202417 Gene_expression of Gata3 16 0.61 7.84 4.12
6 INT202419 Positive_regulation of Gene_expression of Gata3 6 0.52 5.47 2.6
7 INT85085 Positive_regulation of KIT 36 0.53 30.08 2.17
8 INT109327 Negative_regulation of KIT 42 0.57 43.2 2.15
9 INT264967 Positive_regulation of Positive_regulation of PIK3CD 4 0.18 1.97 2.13
10 INT243799 Gene_expression of PIK3CD 15 0.45 6.63 1.5
11 INT116014 Transcription of Gata3 4 0.63 2.24 1.46
12 INT116015 Regulation of Gata3 3 0.22 1.41 1.42
13 INT116008 Binding of Gata3 2 0.34 1.37 1.41
14 INT116016 Positive_regulation of Positive_regulation of Gata3 2 0.21 0.5 1.28
15 INT264969 Localization of PIK3CD 5 0.50 0.64 1.13
16 INT116012 Regulation of Positive_regulation of Gata3 1 0.20 0.07 0.71
17 INT116006 Positive_regulation of Transcription of Gata3 1 0.21 0.07 0.7
18 INT116010 Positive_regulation of Binding of Gata3 1 0.31 0.07 0.7
19 INT202416 Negative_regulation of Gata3 2 0.32 1.17 0.64
20 INT264964 Positive_regulation of Localization of PIK3CD 1 0.13 0.05 0.62
21 INT204254 Localization of KIT 8 0.73 6.78 0.61
22 INT290660 Negative_regulation of Gene_expression of Gata3 1 0.25 1.52 0.6
23 INT129783 Positive_regulation of Gene_expression of KIT 16 0.50 18.12 0.58
24 INT128376 Binding of KIT 26 0.48 14.24 0.47
25 INT186998 Negative_regulation of Gene_expression of KIT 20 0.43 16.77 0.46
26 INT154565 Regulation of Positive_regulation of PIK3CD 2 0.09 1.59 0.45
27 INT337345 Regulation of Gene_expression of PIK3CD 1 0.20 0 0.43
28 INT337344 Negative_regulation of Negative_regulation of PIK3CD 1 0.19 0 0.4
29 INT124944 Regulation of KIT 15 0.60 11.84 0.24
30 INT234614 Phosphorylation of KIT 6 0.78 4.85 0.23
31 INT192957 Transcription of KIT 5 0.69 2.19 0.23
32 INT237188 Negative_regulation of Localization of KIT 1 0.08 0 0.22
33 INT302261 Regulation of PIK3CD 7 0.29 5.34 0.15
34 INT243793 Phosphorylation of PIK3CD 5 0.42 1.74 0.13
35 INT194746 Phosphorylation of Gata3 1 0.10 0.08 0.12
36 INT328448 Negative_regulation of Gene_expression of PIK3CD 1 0.21 0.84 0.08
37 INT295429 Positive_regulation of Phosphorylation of KIT 1 0.42 0.84 0.07
38 INT179325 Negative_regulation of Regulation of KIT 1 0.43 0.82 0.04
39 INT295428 Negative_regulation of Binding of KIT 1 0.36 1.01 0.04
40 INT234613 Positive_regulation of Positive_regulation of KIT 1 0.49 2.41 0.04
41 INT320732 Binding of PIK3CD 3 0.20 1.66 0
42 INT192960 Regulation of Gene_expression of KIT 3 0.45 4.16 0
43 INT192962 Positive_regulation of Transcription of KIT 1 0.46 2.74 0
44 INT217234 Negative_regulation of Transcription of KIT 1 0.24 0.57 0
45 INT292123 Positive_regulation of Negative_regulation of KIT 1 0.10 1.08 0
46 INT234615 Regulation of Positive_regulation of KIT 1 0.44 1.38 0
47 INT311855 Regulation of Negative_regulation of PIK3CD 1 0.04 0.28 0
48 INT337747 Positive_regulation of Localization of KIT 1 0.32 0 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox