GO:0060391

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Name positive regulation of SMAD protein import into nucleus
Categary Process
Go Slim No
Go Link GO:0060391
Unique Molecular Interactions 264
Total Molecular Interactions 328
Total Single Events 2096
Pain Genes Associated 12

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of SMAD protein import into nucleus. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of SMAD protein import into nucleus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
2 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76
3 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 3 0.38 4.29 1.71
4 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63
5 INT75483 Binding of SGCG and TGFB1 1 0.52 2.27 1.19
6 INT142077 TGFB1 Negative_regulation of Binding of IDO1 1 0.15 2.07 1.19
7 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
8 INT75486 Binding of Tgfbr1 and Tgfbr2 1 0.10 1.94 1.02
9 INT129206 RYBP Positive_regulation of Gene_expression of TGFB1 1 0.00 1.04 0.95
10 INT169477 TGFB3 Positive_regulation of Spink3 1 0.02 1.83 0.89
11 INT149559 Tgfb1 Positive_regulation of Gene_expression of Ccr5 1 0.00 0 0.88
12 INT149562 Tgfb1 Positive_regulation of CXCL10 1 0.00 0 0.88
13 INT149564 Tgfb1 Positive_regulation of Gene_expression of CXCL10 1 0.00 0 0.88
14 INT149560 Tgfb1 Positive_regulation of Ccr5 1 0.00 0 0.88
15 INT222985 CP Positive_regulation of Positive_regulation of TGFB1 1 0.00 1.57 0.85
16 INT149561 Tgfb1 Positive_regulation of Gene_expression of CCL2 1 0.00 0 0.83
17 INT149563 Tgfb1 Positive_regulation of CCL2 1 0.00 0 0.83
18 INT149558 Tgfb1 Positive_regulation of Gene_expression of Cxcr4 1 0.00 0 0.82
19 INT149557 Tgfb1 Positive_regulation of Gene_expression of Ccl5 1 0.00 0 0.82
20 INT161485 Il1b Regulation of Gene_expression of TGFB1 1 0.47 1.21 0.77
21 INT161483 Slc7a12 Regulation of Gene_expression of TGFB1 1 0.14 1.21 0.77
22 INT161951 Positive_regulation of TGFBR1 Positive_regulation of Gene_expression of Ngf 1 0.27 0.99 0.76
23 INT161945 TGFB2 Positive_regulation of TGFBR1 1 0.08 0.99 0.76
24 INT161482 Il1b Negative_regulation of TGFB1 1 0.45 1.17 0.76
25 INT161484 Binding of TGFB1 and Il1b 1 0.37 1.16 0.73
26 INT161950 TGFBR1 Negative_regulation of Localization of Ngf 1 0.23 1.01 0.72
27 INT302642 Binding of ARSA and TGFB1 1 0.05 0.28 0.68
28 INT354913 VDR Positive_regulation of TGFB1 1 0.05 1.33 0.67
29 INT137017 Tgfb1 Positive_regulation of Gene_expression of Acta2 1 0.00 0.84 0.61
30 INT335995 Il10 Negative_regulation of Tgfb1 1 0.06 0.83 0.57
31 INT56088 TGFB1 Positive_regulation of Transcription of SERPINE1 1 0.46 0.83 0.57
32 INT302645 ARSA Positive_regulation of Gene_expression of TGFB1 1 0.08 0.28 0.55
33 INT89144 TGFB1 Regulation of Gene_expression of Tcstv1 1 0.00 0.53 0.53
34 INT92918 Atp6v0a2 Negative_regulation of Gene_expression of Tgfb1 1 0.01 0.83 0.52
35 INT302644 ARSA Positive_regulation of Gene_expression of TGFBR1 1 0.04 0.29 0.51
36 INT302647 ARSA Positive_regulation of TGFBR1 1 0.03 0.29 0.51
37 INT138151 Tgfb1 Regulation of IL1B 1 0.01 0.29 0.49
38 INT89145 TGFB1 Positive_regulation of Tcstv1 1 0.00 0.49 0.49
39 INT138153 Tgfb1 Regulation of IL6 1 0.01 0.29 0.49
40 INT302643 ARSA Positive_regulation of Localization of TGFB1 1 0.08 0.12 0.49
41 INT138146 Tgfb1 Regulation of Mmp3 1 0.00 0.23 0.46
42 INT138149 Tgfb1 Regulation of Mmp2 1 0.00 0.23 0.46
43 INT164415 Tgfb1 Regulation of Crlf1 1 0.01 0.78 0.45
44 INT169478 TGFB3 Positive_regulation of Tgfa 1 0.01 0.9 0.44
45 INT169466 TGFB3 Positive_regulation of HRAS 1 0.03 0.89 0.43
46 INT169465 TGFB3 Positive_regulation of MTG1 1 0.03 0.89 0.43
47 INT75488 Binding of TGFB1 and Tgfbr1 1 0.23 0.78 0.41
48 INT75487 Binding of TGFB1 and Tgfbr2 1 0.31 0.83 0.41
49 INT92690 Tgfb1 Positive_regulation of Transcription of Fgf2 1 0.32 1.8 0.4
50 INT165567 Tnf Regulation of Gene_expression of Tgfb1 1 0.41 1.15 0.39
51 INT336340 Glp2r Positive_regulation of Gene_expression of TGFB1 1 0.14 0.67 0.39
52 INT94853 TGFB1 Positive_regulation of Gene_expression of COL7A1 3 0.06 0.57 0.38
53 INT285935 IL6 Positive_regulation of Gene_expression of POU5F1 1 0.14 2.68 0.37
54 INT354886 Thbs1 Regulation of Positive_regulation of Tgfb1 1 0.17 2.18 0.34
55 INT137018 Tgfb1 Positive_regulation of Pscs 1 0.01 0.43 0.34
56 INT137013 Tgfb1 Positive_regulation of Gene_expression of Pscs 1 0.01 0.43 0.34
57 INT225119 Foxm1 Regulation of Localization of TGFB1 1 0.01 0.63 0.34
58 INT333457 Binding of PPARA and TGFB1 1 0.04 0 0.34
59 INT56089 TGFB1 Regulation of SERPINE1 1 0.41 0.41 0.33
60 INT299549 Binding of TGFB1 and Egf 1 0.02 0.32 0.32
61 INT102849 Tgfb1 Positive_regulation of Gene_expression of Col3a1 1 0.04 0.85 0.3
62 INT166165 Binding of TGFB3 and Bmp2 1 0.00 0 0.3
63 INT200640 Agtr2 Positive_regulation of Gene_expression of TGFB1 1 0.03 1.35 0.29
64 INT200639 Ace Positive_regulation of Gene_expression of TGFB1 1 0.06 1.36 0.29
65 INT200631 AGT Positive_regulation of Gene_expression of TGFB1 1 0.06 1.36 0.29
66 INT300552 Napa Positive_regulation of Gene_expression of TGFB1 1 0.01 0.88 0.29
67 INT137033 Tgfb1 Positive_regulation of Gene_expression of Col1a1 1 0.01 0.42 0.28
68 INT225101 TGFB1 Positive_regulation of Localization of COL1A1 1 0.03 0.59 0.28
69 INT225100 TGFB1 Positive_regulation of Gene_expression of COL1A1 1 0.04 0.59 0.28
70 INT137032 Il6 Positive_regulation of Localization of Tgfb1 1 0.04 0.51 0.27
71 INT83395 Binding of IL1RN and Tgfb1 1 0.01 0.17 0.26
72 INT311918 Insrr Negative_regulation of Tgfbr1 1 0.00 0.87 0.26
73 INT311902 Acvrl1 Negative_regulation of Tgfbr1 1 0.13 0.87 0.26
74 INT139094 Csf2 Regulation of Tgfb1 1 0.42 0.58 0.26
75 INT271450 Thy1 Regulation of TGFB1 1 0.00 0.62 0.25
76 INT222981 TGFB1 Positive_regulation of Gene_expression of MMRN1 1 0.09 1.62 0.25
77 INT225098 ZNF630 Regulation of Localization of TGFB1 1 0.01 0.44 0.24
78 INT225105 ZNF630 Regulation of TGFB1 1 0.01 0.44 0.24
79 INT9720 Binding of TGFB1 and Egf 1 0.01 0 0.23
80 INT168710 Ifng Regulation of TGFB1 1 0.00 0.3 0.23
81 INT311911 Tgfbr1 Positive_regulation of Gene_expression of Mmp13 1 0.10 0.55 0.23
82 INT112596 Tgfb1 Negative_regulation of Negative_regulation of Mptp1 1 0.26 0.72 0.22
83 INT112595 Tgfb1 Negative_regulation of Gene_expression of Mptp1 1 0.27 0.72 0.22
84 INT89475 TGFB1 Positive_regulation of Gene_expression of PTHLH 3 0.61 3.64 0.21
85 INT346458 ROS1 Regulation of Localization of TGFB1 1 0.00 1.71 0.21
86 INT114905 TGFB1 Positive_regulation of Transcription of COL7A1 1 0.02 0.08 0.21
87 INT92691 Tgfb1 Positive_regulation of Ctgf 1 0.16 0.91 0.2
88 INT287894 VEGFA Positive_regulation of Localization of BMP4 1 0.04 2.49 0.2
89 INT92692 Tgfb1 Positive_regulation of Gene_expression of Fn1 1 0.27 0.91 0.2
90 INT92693 Tgfb1 Positive_regulation of Fgf2 1 0.32 0.9 0.2
91 INT280260 Tgfb1 Positive_regulation of Cxcr1 1 0.07 1.78 0.19
92 INT280270 Tgfb1 Positive_regulation of Gene_expression of Cxcr4 1 0.08 1.81 0.19
93 INT14869 Binding of EGF and TGFB3 1 0.14 0.69 0.19
94 INT92694 Tgfb1 Positive_regulation of Positive_regulation of Col3a1 1 0.31 0.89 0.19
95 INT280275 Tgfb1 Positive_regulation of VEGFA 1 0.02 2.46 0.19
96 INT153457 Tgfb1 Positive_regulation of Gene_expression of Ctgf 1 0.13 1.15 0.19
97 INT280268 Tgfb1 Positive_regulation of Gene_expression of Vegfa 1 0.06 1.81 0.19
98 INT280266 Tgfb1 Positive_regulation of Vegfa 1 0.09 1.8 0.19
99 INT280261 Tgfb1 Positive_regulation of Gene_expression of Cxcr1 1 0.05 1.81 0.19
100 INT280267 Tgfb1 Positive_regulation of Cxcr4 1 0.11 2.45 0.19
101 INT280274 Tgfb1 Positive_regulation of Gene_expression of VEGFA 1 0.02 2.58 0.19
102 INT350718 Mir106b Regulation of TGFB1 1 0.00 0.42 0.18
103 INT350603 MIR25 Regulation of TGFB1 1 0.01 0.42 0.18
104 INT271451 TGFB1 Regulation of Serpine1 1 0.00 0.68 0.18
105 INT224680 Tgfb1 Negative_regulation of Pten 1 0.00 1.19 0.18
106 INT333449 Binding of SMAD2 and SMAD4 1 0.23 0 0.17
107 INT85334 Agtr2 Regulation of Regulation of Tgfb1 1 0.23 0.68 0.17
108 INT296037 TGFB1 Positive_regulation of IL17A 1 0.02 0 0.17
109 INT160083 TGFB1 Positive_regulation of Gene_expression of L1CAM 1 0.16 1.53 0.16
110 INT85333 Aqp1 Positive_regulation of Negative_regulation of Tgfb1 1 0.25 0.67 0.15
111 INT239323 Binding of Nr1h2 and Positive_regulation of Positive_regulation of Tgfb1 1 0.00 3.71 0.14
112 INT299550 TGFB1 Negative_regulation of Glul 1 0.01 0.34 0.14
113 INT254855 Agt Positive_regulation of Tgfb1 1 0.03 0.18 0.13
114 INT296031 Negative_regulation of TGFB1 Regulation of IL10 1 0.01 1.01 0.13
115 INT296027 TGFB1 Regulation of TH1L 1 0.02 1 0.13
116 INT299547 Negative_regulation of Binding of TGFB1 and Egf 1 0.02 0.1 0.13
117 INT69687 Tgfb1 Positive_regulation of Gene_expression of Il4 1 0.23 0 0.12
118 INT296080 TGFB1 Regulation of Hand2 1 0.01 1 0.12
119 INT331612 ETV4 Positive_regulation of Gene_expression of TGFB1 1 0.00 1.32 0.12
120 INT172976 Mras Regulation of Gene_expression of Smad4 1 0.00 0.83 0.12
121 INT296028 TGFB1 Regulation of IL10 1 0.01 1 0.12
122 INT69688 Tgfb1 Positive_regulation of Rel 1 0.50 0 0.12
123 INT296038 TGFB1 Positive_regulation of Gene_expression of IL23R 1 0.02 0.05 0.11
124 INT299551 Regulation of Binding of TGFB1 and Egf 1 0.03 0.21 0.11
125 INT300313 TGFB1 Positive_regulation of Mapk14 1 0.01 1.5 0.11
126 INT269788 Binding of FN1 and TGFB1 1 0.00 0.29 0.1
127 INT287887 WNT1 Positive_regulation of Localization of BMP4 1 0.04 1.13 0.1
128 INT299555 Lifr Positive_regulation of Gene_expression of TGFB1 1 0.03 0.23 0.09
129 INT116789 Bsg Positive_regulation of Gene_expression of Tgfb1 1 0.00 0.18 0.09
130 INT127143 Binding of IL6 and TGFB1 2 0.01 0.16 0.08
131 INT296041 Binding of TGFB1 and IL21 1 0.01 0.05 0.08
132 INT134832 TGFB1 Regulation of YAP1 1 0.16 0.68 0.08
133 INT134837 TGFB1 Regulation of SMAD7 1 0.34 0.68 0.08
134 INT311917 Gene_expression of Tgfbr1 Positive_regulation of Gene_expression of Mmp13 1 0.10 0.31 0.08
135 INT134833 TGFB1 Regulation of Gene_expression of SMAD7 1 0.34 0.69 0.08
136 INT304330 TGFB1 Positive_regulation of ECM1 1 0.00 0.31 0.08
137 INT251232 Slc17a6 Positive_regulation of Tgfb1 1 0.03 0 0.08
138 INT134835 TGFB1 Regulation of Gene_expression of YAP1 1 0.49 0.69 0.08
139 INT134834 TGFB1 Positive_regulation of YAP1 1 0.55 0.81 0.08
140 INT134838 TGFB1 Positive_regulation of SMAD7 1 0.52 0.79 0.08
141 INT299548 Binding of TGFB1 and Lif 1 0.02 0 0.07
142 INT331629 Binding of TGFB1 and Positive_regulation of Gene_expression of Itk 1 0.00 0.84 0.07
143 INT311915 Tgfbr1 Negative_regulation of Gene_expression of Mmp13 1 0.09 0.27 0.06
144 INT311906 Binding of Smad4 and Insrr 1 0.00 0.18 0.06
145 INT94851 TGFB1 Regulation of Gene_expression of COL7A1 1 0.03 0.06 0.06
146 INT312228 INPP5K Regulation of TGFB1 1 0.06 0.08 0.05
147 INT282552 POU5F1 Positive_regulation of FGF4 1 0.29 0.29 0.05
148 INT343538 TGFB1 Positive_regulation of Gene_expression of GLI2 1 0.08 0.2 0.05
149 INT210261 Bmp4 Regulation of Gene_expression of Tff3 1 0.64 0 0.05
150 INT232206 Binding of Tgfb1 and Tnfsf11 1 0.02 0.52 0.04
151 INT282555 POU5F1 Positive_regulation of Positive_regulation of MAPK1 1 0.11 0.28 0.04
152 INT282556 POU5F1 Positive_regulation of GOPC 1 0.06 0.06 0.04
153 INT353290 Binding of Smad2 and Smad4 1 0.20 0.08 0.04
154 INT232207 Binding of Tgfb1 and Tnfrsf11a 1 0.02 0.51 0.04
155 INT285936 IL17A Positive_regulation of Gene_expression of POU5F1 1 0.10 0.34 0.04
156 INT353295 Binding of Smad3 and Smad4 1 0.17 0.08 0.04
157 INT271452 Binding of TGFB1 and Eln 1 0.00 0.38 0.04
158 INT271449 Binding of TGFB1 and Lox 1 0.01 0.38 0.04
159 INT282561 POU5F1 Positive_regulation of Gene_expression of NANOG 1 0.11 0.26 0.04
160 INT306560 BMP4 Positive_regulation of MAPK1 1 0.09 0.09 0.03
161 INT282543 KDM4C Regulation of POU5F1 1 0.06 0.08 0.03
162 INT265347 Binding of Ocln and Tgfbr1 1 0.18 0.06 0.03
163 INT265345 Binding of Tgfbr1 and Tjp1 1 0.09 0.06 0.03
164 INT280263 Binding of Smad4 and Proc 1 0.00 1.26 0.03
165 INT282542 KDM3A Regulation of POU5F1 1 0.06 0.08 0.03
166 INT282553 POU5F1 Positive_regulation of REXO1 1 0.21 0.1 0.03
167 INT265343 Positive_regulation of Binding of Tgfbr1 and Tjp1 1 0.12 0.06 0.03
168 INT265348 Positive_regulation of Binding of Ocln and Tgfbr1 1 0.25 0.06 0.03
169 INT277927 WIF1 Negative_regulation of SMAD4 1 0.23 0.37 0
170 INT340086 Binding of Tgfb1 and Cndp2 1 0.04 0.38 0
171 INT157811 TGFB1 Positive_regulation of Timp2 1 0.02 0.06 0
172 INT314865 Binding of Ltbp3 and Tgfb1 1 0.24 0.51 0
173 INT265231 Binding of FKBP1A and TGFBR1 1 0.11 0.35 0
174 INT312221 Binding of TGFB1 and INPP5K 1 0.09 0 0
175 INT280262 Binding of Tgfb1 and Positive_regulation of Cxcr4 1 0.07 1.27 0
176 INT280276 Binding of Tgfb1 and Positive_regulation of VEGFA 1 0.02 1.27 0
177 INT121314 Tgfb1 Positive_regulation of Egfr 1 0.08 0.16 0
178 INT180855 TGFB1 Regulation of S100A10 1 0.06 0.69 0
179 INT282559 NANOG Regulation of POU5F1 1 0.14 0.45 0
180 INT282554 Binding of POU5F1 and SOX2 1 0.19 0.1 0
181 INT121316 Tgfb1 Negative_regulation of Xrcc1 1 0.06 0.08 0
182 INT121318 Tgfb1 Negative_regulation of Ercc1 1 0.06 0.08 0
183 INT193308 Binding of PRNP and TGFB1 1 0.01 0 0
184 INT184955 EGR1 Regulation of Regulation of TGFB1 1 0.39 0.3 0
185 INT337915 Tgfbr1 Positive_regulation of Negative_regulation of Smad2 1 0.05 0.15 0
186 INT265344 sb Negative_regulation of Tgfbr1 1 0.00 0.06 0
187 INT280265 Binding of Cxcr4 and Tgfb1 1 0.06 0.89 0
188 INT180860 TGFB1 Regulation of Transcription of NID2 1 0.23 0.77 0
189 INT212770 Binding of CTD and TGFB1 1 0.01 3.95 0
190 INT268345 Binding of TGFB1 and TGFBR2 1 0.27 0.62 0
191 INT254848 Tgfb1 Negative_regulation of Rhoa 1 0.02 0 0
192 INT282551 SOX2 Regulation of POU5F1 1 0.24 0.45 0
193 INT254863 Tgfb1 Positive_regulation of Transcription of Smad3 1 0.03 0.23 0
194 INT248948 Binding of Klrd1 and Tgfb1 1 0.04 0.16 0
195 INT157813 TGFB1 Positive_regulation of Gene_expression of Tagln 1 0.11 0.06 0
196 INT121313 Tgfb1 Positive_regulation of Ercc1 1 0.07 0.08 0
197 INT196023 Bmp2 Negative_regulation of Gene_expression of Bmp4 1 0.09 0.07 0
198 INT282541 SOX2 Regulation of Transcription of POU5F1 1 0.24 0.05 0
199 INT268341 SMAD2 Positive_regulation of SMAD4 1 0.31 0.56 0
200 INT248947 Binding of Cd8a and Tgfb1 1 0.05 0.16 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of SMAD protein import into nucleus. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of SMAD protein import into nucleus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18
2 INT48202 Gene_expression of Tgfb1 146 0.78 89.93 27.76
3 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23
4 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2
5 INT12081 Localization of TGFB1 64 0.81 35.4 17.47
6 INT36336 Gene_expression of Tgfb1 41 0.77 21.82 14.53
7 INT48203 Positive_regulation of Tgfb1 67 0.70 41.31 11.07
8 INT61120 Positive_regulation of Gene_expression of Tgfb1 34 0.70 21.15 6.93
9 INT48201 Localization of Tgfb1 27 0.59 13.65 5.54
10 INT48200 Transcription of Tgfb1 13 0.69 3.85 5.24
11 INT67868 Negative_regulation of Gene_expression of Tgfb1 18 0.43 14.27 5.16
12 INT89104 Binding of TGFB1 29 0.44 13.67 5.12
13 INT89103 Regulation of Gene_expression of TGFB1 15 0.56 8.11 4.37
14 INT154527 Gene_expression of POU5F1 180 0.78 34.01 4.34
15 INT36335 Localization of Tgfb1 19 0.79 7.06 4.17
16 INT69681 Negative_regulation of Tgfb1 42 0.51 22.28 4
17 INT12083 Regulation of TGFB1 22 0.53 15.4 3.6
18 INT51848 Transcription of TGFB1 17 0.69 9.57 3.53
19 INT56300 Negative_regulation of Gene_expression of TGFB1 13 0.41 4.87 3.5
20 INT69216 Positive_regulation of Tgfb1 14 0.49 5.84 3.29
21 INT85147 Positive_regulation of Gene_expression of Tgfb1 12 0.46 7.29 3.24
22 INT85149 Negative_regulation of Gene_expression of Tgfb1 11 0.42 4.73 3.19
23 INT75484 Gene_expression of Tgfbr1 21 0.64 13.36 3.15
24 INT112667 Negative_regulation of Tgfb1 9 0.58 2.72 2.97
25 INT14872 Gene_expression of TGFB3 15 0.55 12.45 2.96
26 INT9130 Negative_regulation of TGFB1 16 0.41 12.21 2.92
27 INT48199 Regulation of Tgfb1 17 0.54 9.57 2.74
28 INT48198 Binding of Tgfb1 29 0.47 19.59 2.46
29 INT12086 Regulation of Localization of TGFB1 4 0.43 1.65 2.09
30 INT107178 Gene_expression of Smad4 12 0.65 9.85 1.92
31 INT74824 Positive_regulation of Transcription of TGFB1 6 0.67 2.58 1.84
32 INT120088 Gene_expression of Bmp4 37 0.73 13.89 1.73
33 INT86712 Regulation of Gene_expression of Tgfb1 2 0.15 2.03 1.65
34 INT84310 Regulation of Gene_expression of Tgfb1 7 0.29 6.6 1.63
35 INT120071 Negative_regulation of Positive_regulation of Tgfb1 4 0.16 4.06 1.55
36 INT110992 Positive_regulation of Positive_regulation of TGFB1 4 0.50 3.01 1.51
37 INT228040 Negative_regulation of Transcription of Tgfb1 1 0.04 0.49 1.42
38 INT12085 Positive_regulation of Localization of TGFB1 7 0.42 4.9 1.4
39 INT282590 Positive_regulation of Gene_expression of POU5F1 40 0.70 8.42 1.32
40 INT173892 Phosphorylation of TGFB1 8 0.79 2.63 1.3
41 INT310164 Negative_regulation of Gene_expression of Tgfbr1 9 0.40 6.11 1.17
42 INT282572 Positive_regulation of POU5F1 24 0.70 5.8 1.13
43 INT120858 Positive_regulation of Localization of Tgfb1 7 0.68 1.46 1.03
44 INT128717 Regulation of Tgfb1 6 0.61 1.94 0.94
45 INT123852 Negative_regulation of Positive_regulation of Tgfb1 3 0.28 1.69 0.94
46 INT265313 Positive_regulation of Tgfbr1 8 0.66 2.95 0.87
47 INT142122 Regulation of Gene_expression of Bmp4 5 0.43 2.69 0.86
48 INT139322 Negative_regulation of Negative_regulation of Tgfb1 1 0.53 0 0.86
49 INT85148 Transcription of Tgfb1 5 0.52 1.91 0.84
50 INT102848 Negative_regulation of Localization of Tgfb1 3 0.10 1.81 0.83
51 INT210247 Positive_regulation of Bmp4 6 0.65 4.36 0.8
52 INT139323 Positive_regulation of Negative_regulation of Tgfb1 1 0.45 0 0.79
53 INT14871 Binding of TGFB3 3 0.13 1.2 0.78
54 INT161947 Positive_regulation of TGFBR1 2 0.52 1.6 0.76
55 INT291617 Negative_regulation of Transcription of TGFB1 2 0.15 0.61 0.76
56 INT90790 Regulation of Localization of Tgfb1 2 0.29 0.46 0.75
57 INT282599 Regulation of Gene_expression of POU5F1 10 0.62 4.89 0.71
58 INT172960 Negative_regulation of Gene_expression of Smad4 7 0.39 5.88 0.71
59 INT337046 Positive_regulation of Binding of Tgfb1 1 0.30 1.1 0.69
60 INT121302 Positive_regulation of Localization of Tgfb1 5 0.07 1.91 0.67
61 INT114909 Negative_regulation of Localization of TGFB1 5 0.36 1.37 0.66
62 INT111891 Regulation of Transcription of Tgfb1 1 0.04 0.68 0.64
63 INT96422 Gene_expression of Bmp4 18 0.69 3.26 0.63
64 INT114910 Negative_regulation of Positive_regulation of TGFB1 3 0.34 0.92 0.6
65 INT173891 Positive_regulation of Phosphorylation of TGFB1 4 0.49 2 0.59
66 INT138140 Protein_catabolism of Tgfb1 2 0.09 0.87 0.59
67 INT144922 Gene_expression of TGFBR1 4 0.72 0.19 0.57
68 INT103781 Negative_regulation of Smad4 9 0.42 4.42 0.54
69 INT69683 Positive_regulation of Transcription of Tgfb1 1 0.67 0 0.53
70 INT230634 Negative_regulation of POU5F1 10 0.43 1.03 0.46
71 INT142124 Binding of Bmp4 1 0.35 0.46 0.45
72 INT71019 Negative_regulation of SMAD4 12 0.42 6.88 0.43
73 INT180688 Transcription of Bmp4 3 0.58 0.35 0.41
74 INT180702 Positive_regulation of Transcription of Bmp4 3 0.42 0.35 0.41
75 INT27659 Localization of TGFB3 3 0.29 0.52 0.4
76 INT292484 Negative_regulation of TGFBR1 3 0.19 0.75 0.39
77 INT117564 Gene_expression of SMAD4 12 0.71 8.7 0.37
78 INT69680 Positive_regulation of Positive_regulation of Tgfb1 3 0.67 1.04 0.35
79 INT254816 Negative_regulation of Tgfbr1 20 0.55 9.24 0.34
80 INT92100 Binding of Smad4 5 0.31 2.23 0.3
81 INT14873 Positive_regulation of Gene_expression of TGFB3 2 0.25 1.14 0.29
82 INT311881 Regulation of Positive_regulation of Tgfbr1 1 0.22 0.97 0.29
83 INT159213 Gene_expression of BMP4 8 0.74 2.1 0.28
84 INT159212 Positive_regulation of Gene_expression of BMP4 2 0.66 0.91 0.28
85 INT282571 Negative_regulation of Positive_regulation of POU5F1 1 0.38 0 0.28
86 INT185009 Negative_regulation of BMP4 2 0.56 1.04 0.25
87 INT251228 Phosphorylation of Tgfb1 4 0.15 1.18 0.24
88 INT299545 Positive_regulation of Binding of TGFB1 2 0.06 1.08 0.22
89 INT142121 Positive_regulation of Gene_expression of Bmp4 3 0.47 7 0.21
90 INT61823 Positive_regulation of TGFB3 2 0.01 1.64 0.2
91 INT311886 Phosphorylation of Tgfbr1 1 0.40 0.7 0.19
92 INT120085 Negative_regulation of Gene_expression of Bmp4 5 0.55 0.61 0.17
93 INT277935 Binding of SMAD4 4 0.28 1.12 0.17
94 INT85330 Positive_regulation of Regulation of Tgfb1 1 0.41 0.67 0.17
95 INT122201 Binding of Tgfb1 1 0.16 0.17 0.17
96 INT282576 Negative_regulation of Gene_expression of POU5F1 12 0.43 2.79 0.16
97 INT133100 Negative_regulation of Localization of Tgfb1 2 0.28 1.48 0.15
98 INT139977 Regulation of Smad4 1 0.16 1.41 0.15
99 INT302662 Negative_regulation of Negative_regulation of TGFBR1 1 0.14 0 0.13
100 INT278790 Binding of POU5F1 8 0.43 0.67 0.11
101 INT81940 Regulation of TGFB3 3 0.14 0.45 0.1
102 INT287912 Localization of BMP4 1 0.18 1.13 0.1
103 INT196033 Negative_regulation of Gene_expression of Bmp4 3 0.21 0.45 0.09
104 INT14738 Negative_regulation of Regulation of TGFB1 2 0.41 0.81 0.09
105 INT254819 Regulation of Negative_regulation of Tgfbr1 1 0.15 1.2 0.09
106 INT325510 Transcription of Smad4 1 0.67 0.16 0.09
107 INT331623 Negative_regulation of Binding of TGFB1 1 0.02 1.02 0.08
108 INT278785 Positive_regulation of Binding of POU5F1 2 0.45 0.19 0.07
109 INT210243 Negative_regulation of Bmp4 1 0.55 0.55 0.07
110 INT311885 Positive_regulation of Gene_expression of Tgfbr1 2 0.44 0.35 0.06
111 INT254790 Localization of Smad4 2 0.37 0.54 0.06
112 INT139093 Regulation of Negative_regulation of Tgfb1 1 0.27 0.44 0.06
113 INT216377 Transcription of POU5F1 9 0.69 0.58 0.05
114 INT251230 Positive_regulation of Negative_regulation of Tgfb1 1 0.09 0 0.05
115 INT136115 Positive_regulation of Regulation of TGFB1 1 0.11 0.16 0.05
116 INT282603 Positive_regulation of Positive_regulation of POU5F1 1 0.45 0 0.05
117 INT196030 Positive_regulation of Bmp4 6 0.62 2.55 0.04
118 INT210238 Positive_regulation of Negative_regulation of Bmp4 1 0.47 0 0.04
119 INT253182 Positive_regulation of Positive_regulation of Bmp4 1 0.45 0.58 0.04
120 INT334291 Positive_regulation of Gene_expression of SMAD4 1 0.18 0 0.04
121 INT185020 Positive_regulation of Negative_regulation of TGFB1 1 0.43 0.44 0.04
122 INT268360 Positive_regulation of SMAD4 3 0.55 1.55 0.03
123 INT180881 Regulation of Positive_regulation of TGFB1 2 0.32 1.32 0.03
124 INT282944 Negative_regulation of Negative_regulation of POU5F1 1 0.11 0 0.03
125 INT117563 Negative_regulation of Gene_expression of SMAD4 6 0.54 3.87 0
126 INT282605 Regulation of POU5F1 4 0.55 0.4 0
127 INT196034 Positive_regulation of Gene_expression of Bmp4 4 0.45 0.63 0
128 INT260779 Negative_regulation of Bmp4 4 0.23 0.94 0
129 INT282585 Localization of POU5F1 3 0.67 0.08 0
130 INT196027 Binding of Bmp4 2 0.13 0.97 0
131 INT334327 Regulation of SMAD4 2 0.35 1.73 0
132 INT142119 Regulation of Bmp4 2 0.58 0.29 0
133 INT265316 Binding of Tgfbr1 2 0.35 0.59 0
134 INT265326 Regulation of Tgfbr1 2 0.43 0.17 0
135 INT278808 Regulation of Binding of POU5F1 1 0.01 0 0
136 INT268368 Transcription of SMAD4 1 0.54 1.7 0
137 INT315214 Negative_regulation of Regulation of Tgfbr1 1 0.41 0 0
138 INT133097 Positive_regulation of Phosphorylation of Tgfb1 1 0.05 0.07 0
139 INT268388 Positive_regulation of Positive_regulation of TGFBR1 1 0.35 0.61 0
140 INT309646 Negative_regulation of Transcription of POU5F1 1 0.43 0 0
141 INT339667 Localization of Bmp4 1 0.38 0.27 0
142 INT173000 Negative_regulation of Localization of SMAD4 1 0.22 0.98 0
143 INT173008 Localization of SMAD4 1 0.38 0.97 0
144 INT254788 Negative_regulation of Regulation of Tgfb1 1 0.06 0.61 0
145 INT272228 Localization of TGFBR1 1 0.34 0.74 0
146 INT254800 Positive_regulation of Phosphorylation of Tgfb1 1 0.04 0.24 0
147 INT133099 Negative_regulation of Phosphorylation of Tgfb1 1 0.04 0.08 0
148 INT334289 Regulation of Binding of SMAD4 1 0.16 0 0
149 INT294842 Positive_regulation of Negative_regulation of POU5F1 1 0.41 0.49 0
150 INT265319 Positive_regulation of Negative_regulation of Tgfbr1 1 0.47 0.53 0
151 INT334288 Regulation of Negative_regulation of SMAD4 1 0.16 0 0
152 INT144920 Positive_regulation of Gene_expression of TGFBR1 1 0.65 0 0
153 INT133098 Phosphorylation of Tgfb1 1 0.06 0.07 0
154 INT128712 Positive_regulation of Regulation of Tgfb1 1 0.15 0 0
155 INT228250 Positive_regulation of Smad4 1 0.45 1.93 0
156 INT310176 Localization of Tgfbr1 1 0.11 0.83 0
157 INT310179 Positive_regulation of Positive_regulation of Tgfbr1 1 0.08 0 0
158 INT351554 Negative_regulation of Gene_expression of BMP4 1 0.26 0 0
159 INT228247 Regulation of Positive_regulation of Smad4 1 0.26 0.97 0
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