GO:0060395

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Name SMAD protein signal transduction
Categary Process
Go Slim No
Go Link GO:0060395
Unique Molecular Interactions 937
Total Molecular Interactions 1332
Total Single Events 22630
Pain Genes Associated 30

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for SMAD protein signal transduction. They are ordered first by their pain relevance and then by number of times they were reported for SMAD protein signal transduction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT11250 Cck Positive_regulation of Gene_expression of Fos 14 0.78 0.08 7.29
2 INT186566 Hpcl1 Positive_regulation of Fos 1 0.17 0.38 4.49
3 INT11252 Cck Positive_regulation of Fos 6 0.78 0 3.79
4 INT115690 Negative_regulation of Prkcg Negative_regulation of Gene_expression of Fos 1 0.47 0.72 3.63
5 INT17317 Binding of Jun and Fos 7 0.42 1.03 3.5
6 INT190167 Binding of JUN and MMP12 1 0.26 0.82 2.76
7 INT127621 Bst1 Regulation of Positive_regulation of Fos 1 0.26 0 2.73
8 INT54489 Binding of Jun and Rabep2 4 0.16 1.48 2.3
9 INT146520 Tmem132a Regulation of Gene_expression of Fos 1 0.69 0.5 2.18
10 INT117794 Hpcl1 Positive_regulation of Gene_expression of Fos 3 0.17 0.15 1.98
11 INT54488 Npepo Regulation of Gene_expression of Jun 1 0.30 0 1.98
12 INT125348 Decr1 Regulation of Gene_expression of Fos 1 0.00 0.1 1.92
13 INT50993 Il1b Positive_regulation of Fos 2 0.40 0.43 1.84
14 INT112526 D2Mit212 Negative_regulation of Gene_expression of Fos 1 0.03 0.28 1.8
15 INT146512 Tmem132a Negative_regulation of Gene_expression of Fos 1 0.23 0 1.76
16 INT139640 Jun Regulation of Gene_expression of Npy 1 0.21 1.98 1.75
17 INT94203 SP5 Positive_regulation of FOS 1 0.25 1.41 1.72
18 INT160304 Npy Regulation of Gene_expression of Fos 3 0.67 1.43 1.68
19 INT54484 Npepo Positive_regulation of Gene_expression of Fos 1 0.43 0 1.63
20 INT105112 Plat Positive_regulation of JUN 1 0.01 1.55 1.58
21 INT158877 PRS Positive_regulation of Gene_expression of Fos 1 0.09 5.14 1.54
22 INT79021 Regulation of Binding of Jun and Fos 2 0.50 0.66 1.5
23 INT3573 Tf Negative_regulation of Localization of Gh1 1 0.36 0 1.49
24 INT72319 Adarb1 Positive_regulation of Gene_expression of Fos 3 0.10 0.1 1.44
25 INT68723 Pomgnt1 Negative_regulation of Gene_expression of Fos 1 0.12 0 1.41
26 INT108583 Binding of Vip and Fos 1 0.36 0 1.39
27 INT94630 Positive_regulation of Adarb1 Positive_regulation of Gene_expression of Fos 2 0.03 0.1 1.32
28 INT120929 Prkcg Regulation of Gene_expression of Fos 2 0.50 0.34 1.31
29 INT66428 Dcc Positive_regulation of Fos 2 0.05 0.39 1.29
30 INT89873 Pdyn Positive_regulation of Gene_expression of Gata4 1 0.23 0 1.29
31 INT89876 Pdyn Positive_regulation of Gata4 1 0.23 0 1.28
32 INT70181 PRCP Positive_regulation of FOS 1 0.58 0.36 1.26
33 INT114635 Hmox2 Positive_regulation of Gene_expression of Fos 1 0.47 0.88 1.26
34 INT287104 Binding of Ntrk2 and T 1 0.20 3.29 1.26
35 INT141244 Fos Regulation of Prkaca 1 0.18 0.07 1.24
36 INT71443 CSAD Positive_regulation of Gene_expression of Fos 1 0.58 0.81 1.23
37 INT159837 Trim2 Negative_regulation of Transcription of Fos 1 0.10 1.92 1.22
38 INT109380 Binding of Adarb1 and Fos 1 0.02 0.38 1.19
39 INT73075 Adarb1 Regulation of Fos 1 0.01 0.07 1.18
40 INT150191 CEACAM3 Positive_regulation of Gene_expression of FOS 1 0.34 0.14 1.16
41 INT123454 CNR1 Regulation of Fos 1 0.00 0.06 1.12
42 INT130471 Prkcg Regulation of Regulation of Fos 1 0.45 0.27 1.12
43 INT112608 DNAJC15 Regulation of Gene_expression of Fos 1 0.02 0.14 1.12
44 INT123455 CNR1 Regulation of Positive_regulation of Fos 1 0.00 0.06 1.12
45 INT143941 Il1f5 Negative_regulation of Gene_expression of Fos 1 0.00 1.03 1.11
46 INT102421 POMC Regulation of Gene_expression of Fos 1 0.12 0.34 1.11
47 INT105423 Jun Positive_regulation of Gene_expression of Penk 1 0.43 0 1.09
48 INT164382 MAPK3 Positive_regulation of Gene_expression of Fos 1 0.75 0.2 1.08
49 INT164383 Positive_regulation of MAPK3 Positive_regulation of Gene_expression of Fos 1 0.54 0.2 1.08
50 INT132701 Adarb1 Negative_regulation of Gene_expression of Fos 1 0.01 0.73 1.07
51 INT100564 CRX Positive_regulation of Fos 1 0.04 0.89 1.06
52 INT105109 Cxcl12 Positive_regulation of JUN 1 0.01 1.07 1.05
53 INT270680 Fos Regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 1 0.03 0.39 1.05
54 INT214875 Ap3d1 Negative_regulation of Gene_expression of Fos 1 0.00 0.39 1.04
55 INT146518 Tmem132a Positive_regulation of Gene_expression of Fos 1 0.68 0.06 1.04
56 INT95378 Binding of Jun and Jund 5 0.20 2.06 1.02
57 INT74027 Creb1 Regulation of Jun 4 0.27 1.04 1.02
58 INT101065 MAP3K15 Positive_regulation of JUN 1 0.43 0.46 1.02
59 INT139636 Jun Negative_regulation of Phosphorylation of Npy 1 0.33 1.07 1.01
60 INT265070 Reln Positive_regulation of Gene_expression of Fos 1 0.02 0.51 1.01
61 INT143177 Apcs Negative_regulation of Gene_expression of Fos 1 0.02 0.36 1.01
62 INT113453 Ngf Positive_regulation of JUN 1 0.27 0.6 1.01
63 INT11251 Negative_regulation of Cck Positive_regulation of Fos 2 0.48 0 1
64 INT139639 Jun Negative_regulation of Positive_regulation of Vip 1 0.53 1.07 1
65 INT139643 Jun Negative_regulation of Positive_regulation of Npy 1 0.33 1.07 1
66 INT71319 Binding of Penk and Fos 3 0.40 0.15 0.99
67 INT139641 Positive_regulation of Jun Positive_regulation of Positive_regulation of Vip 1 0.37 0.95 0.99
68 INT94206 SP5 Regulation of Gene_expression of FOS 1 0.22 0.7 0.98
69 INT139642 Positive_regulation of Jun Regulation of Gene_expression of Npy 1 0.21 1.07 0.97
70 INT145823 Ngf Positive_regulation of Fos 1 0.52 0.95 0.97
71 INT281375 Il1r1 Negative_regulation of Gene_expression of Fos 1 0.47 0.61 0.97
72 INT145824 Negative_regulation of Ngf Positive_regulation of Fos 1 0.48 0.95 0.97
73 INT93234 Negative_regulation of Pde4b Negative_regulation of Gene_expression of Fos 1 0.41 0.1 0.96
74 INT281380 Fos Negative_regulation of Gene_expression of FSCN1 1 0.07 0.4 0.96
75 INT139638 Positive_regulation of Jun Positive_regulation of Positive_regulation of Npy 1 0.36 1.18 0.96
76 INT103833 Sp5 Positive_regulation of Fos 1 0.51 0 0.96
77 INT155044 Negative_regulation of Ceacam3 Negative_regulation of Gene_expression of Fos 1 0.61 0 0.95
78 INT127263 Adra2a Regulation of Gene_expression of Jun 1 0.07 1.1 0.95
79 INT165941 Bmp7 Positive_regulation of Penk 1 0.28 0.43 0.95
80 INT165942 Bmp7 Positive_regulation of Transcription of Pomc 1 0.29 0.43 0.95
81 INT155043 Vta1 Regulation of Gene_expression of Fos 1 0.08 0 0.95
82 INT165940 Bmp7 Positive_regulation of Pomc 1 0.29 0.43 0.95
83 INT210783 Bmp2 Positive_regulation of Tnip1 1 0.40 0.53 0.94
84 INT152390 Negative_regulation of Binding of JUN and OPRM1 1 0.13 0.14 0.94
85 INT80601 Akr1d1 Regulation of Positive_regulation of Fos 1 0.06 0 0.94
86 INT152387 Binding of JUN and OPRM1 1 0.15 0.14 0.94
87 INT330629 TP53 Negative_regulation of Gene_expression of Fos 1 0.30 1.76 0.94
88 INT48148 Fos Positive_regulation of Gene_expression of Pdyn 1 0.21 0 0.94
89 INT186568 Hpcl1 Regulation of Gene_expression of Fos 1 0.22 0.07 0.94
90 INT281377 FSCN1 Positive_regulation of Gene_expression of Fos 1 0.08 0.49 0.93
91 INT89514 Pnoc Regulation of Gene_expression of Fos 1 0.47 0.98 0.93
92 INT120380 Cnr1 Positive_regulation of Gene_expression of Fos 1 0.31 0.45 0.93
93 INT210791 Bmp2 Positive_regulation of Net1 1 0.38 0.52 0.93
94 INT143578 Olr404 Negative_regulation of Positive_regulation of Fos 1 0.01 0.39 0.93
95 INT210799 Bmp2 Positive_regulation of B2m 1 0.35 0.52 0.92
96 INT86350 Negative_regulation of Adarb1 Negative_regulation of Positive_regulation of Fos 1 0.04 0.8 0.92
97 INT151263 Jun Positive_regulation of S100a8 1 0.00 0.95 0.92
98 INT86349 Negative_regulation of Tacr1 Negative_regulation of Positive_regulation of Fos 1 0.42 0.8 0.92
99 INT66536 Il1a Regulation of Gene_expression of Fos 1 0.59 0 0.91
100 INT166221 Negative_regulation of Gls Negative_regulation of Gene_expression of Fos 1 0.50 0.37 0.9
101 INT249347 Binding of FOS and JUN 4 0.19 6.15 0.89
102 INT164677 Ngf Positive_regulation of Gene_expression of Fos 1 0.52 0.08 0.89
103 INT87416 SNORD50A Regulation of Positive_regulation of Fos 1 0.13 0 0.87
104 INT73653 Binding of Creb1 and Fos 1 0.40 1.49 0.87
105 INT161308 POMC Negative_regulation of Positive_regulation of JUN 1 0.12 0.27 0.86
106 INT124878 Gnat3 Negative_regulation of Gene_expression of FOS 1 0.09 0.16 0.85
107 INT60719 Insrr Positive_regulation of Fos 1 0.03 1.23 0.84
108 INT161307 JUN Positive_regulation of IL2 1 0.14 0.25 0.84
109 INT122833 AP1B1 Regulation of Gene_expression of Fos 1 0.16 0 0.83
110 INT108072 Grip2 Positive_regulation of Gene_expression of Fos 1 0.08 0.21 0.82
111 INT329278 Vta1 Positive_regulation of Gene_expression of Fos 1 0.22 0 0.82
112 INT186567 Negative_regulation of Hpcl1 Positive_regulation of Fos 1 0.11 0.07 0.82
113 INT124877 Gnat3 Negative_regulation of FOS 1 0.09 0.15 0.82
114 INT124876 Gnat3 Negative_regulation of Positive_regulation of FOS 1 0.09 0.15 0.82
115 INT341367 CRX Positive_regulation of Positive_regulation of FOS 1 0.04 0.83 0.8
116 INT190182 JUN Positive_regulation of MMP12 1 0.34 0.08 0.8
117 INT111129 Adarb1 Regulation of Gene_expression of Fos 1 0.09 0 0.79
118 INT200094 Negative_regulation of Jun Negative_regulation of Gene_expression of Ptgs2 1 0.01 2.87 0.78
119 INT166222 Gene_expression of Fos Positive_regulation of Col6a6 1 0.01 0.57 0.77
120 INT200097 Negative_regulation of Binding of Il1a and Jun 1 0.00 2.76 0.77
121 INT90120 Jun Positive_regulation of Gene_expression of Nos1 1 0.38 0.39 0.76
122 INT90118 Jun Regulation of Gene_expression of Nfkb1 1 0.18 0.39 0.76
123 INT73087 Adarb1 Positive_regulation of Fos 1 0.02 0 0.76
124 INT90117 Jun Regulation of Gene_expression of Nos1 1 0.21 0.39 0.76
125 INT108073 Pnoc Negative_regulation of Gene_expression of Fos 1 0.32 0.25 0.76
126 INT200093 Binding of Il1a and Jun 1 0.00 2.64 0.76
127 INT90123 Jun Positive_regulation of Gene_expression of Fos 1 0.47 0.39 0.76
128 INT142057 NLRP1 Regulation of Gene_expression of Fos 1 0.17 0 0.76
129 INT90122 Nfkb1 Positive_regulation of Gene_expression of Fos 1 0.39 0.39 0.75
130 INT83868 Oprd1 Positive_regulation of Gene_expression of Fos 1 0.01 0 0.75
131 INT151809 JUN Positive_regulation of Positive_regulation of OPRM1 1 0.32 0 0.74
132 INT168420 Positive_regulation of Mapk8 Positive_regulation of Phosphorylation of Jun 1 0.30 0.88 0.74
133 INT190169 Regulation of JUN Positive_regulation of Localization of MMP12 1 0.30 0.07 0.74
134 INT106527 Akt1 Positive_regulation of Jun 1 0.05 0.53 0.74
135 INT186436 Phosphorylation of Creb1 Regulation of Transcription of Jun 1 0.21 0.44 0.73
136 INT186445 Creb1 Regulation of Transcription of FOS 1 0.49 0.44 0.73
137 INT186443 Phosphorylation of Creb1 Regulation of Transcription of FOS 1 0.49 0.44 0.73
138 INT186438 Creb1 Regulation of Transcription of Jun 1 0.21 0.44 0.73
139 INT186444 Creb1 Regulation of FOS 1 0.49 0.43 0.72
140 INT108582 Binding of Grp and Fos 1 0.32 0 0.72
141 INT186442 Phosphorylation of Creb1 Regulation of FOS 1 0.49 0.43 0.72
142 INT186440 Phosphorylation of Creb1 Regulation of Jun 1 0.21 0.43 0.72
143 INT108584 Binding of GRP and Fos 1 0.04 0 0.72
144 INT772 Tf Positive_regulation of Positive_regulation of Oprl1 1 0.11 0 0.7
145 INT778 Tf Positive_regulation of Gh1 1 0.14 0 0.7
146 INT159569 Negative_regulation of Alox5 Negative_regulation of Gene_expression of Fos 1 0.37 0.4 0.7
147 INT60371 Fos Positive_regulation of Pdyn 1 0.41 0.1 0.7
148 INT782 Tf Positive_regulation of Prl 1 0.43 0 0.7
149 INT287099 Binding of Bdnf and T 1 0.10 1.1 0.69
150 INT141171 Ptz1a Positive_regulation of Gene_expression of Fos 1 0.07 0.5 0.69
151 INT66581 Binding of JUN and Rare2 1 0.00 0.07 0.69
152 INT66582 Binding of FOS and Rare2 1 0.00 0.07 0.69
153 INT120381 Binding of CNR1 and Fos 1 0.00 0.52 0.68
154 INT66537 IL1B Positive_regulation of Gene_expression of Fos 1 0.02 0 0.68
155 INT124257 Plat Positive_regulation of Jun 5 0.12 3.33 0.67
156 INT92025 Egr1 Positive_regulation of Jun 1 0.15 0.61 0.67
157 INT232622 Magi2 Regulation of Cysltr1 1 0.01 0.58 0.67
158 INT92026 Egr1 Positive_regulation of Fos 1 0.50 0.61 0.67
159 INT153532 NMS Regulation of Gene_expression of Fos 1 0.23 1.33 0.67
160 INT110407 Htr1a Positive_regulation of Gene_expression of Fos 1 0.50 0.52 0.66
161 INT62059 Positive_regulation of SCN5A Positive_regulation of Gene_expression of FOS 1 0.01 0.42 0.66
162 INT186569 Regulation of Hpcl1 Positive_regulation of Fos 1 0.07 0 0.65
163 INT82306 Bdnf Positive_regulation of Gene_expression of Fos 1 0.68 0.64 0.65
164 INT128869 Gabrg1 Positive_regulation of Transcription of Jun 1 0.09 0.55 0.62
165 INT54487 Rabep2 Regulation of Gene_expression of Jun 1 0.06 0 0.61
166 INT97916 Tinag Negative_regulation of Gene_expression of Fos 1 0.01 0.35 0.6
167 INT40901 Trf Regulation of Localization of POMC 1 0.07 0.56 0.6
168 INT81916 HSF1 Positive_regulation of FOS 1 0.76 0.66 0.59
169 INT128604 Casp1 Positive_regulation of Gene_expression of Fos 1 0.10 0.55 0.59
170 INT128606 Pomc Positive_regulation of Gene_expression of Fos 1 0.02 0.55 0.59
171 INT76237 Olr594 Positive_regulation of Gene_expression of Fos 1 0.05 0.09 0.59
172 INT81918 HSF1 Negative_regulation of FOS 1 0.64 0.66 0.59
173 INT178437 Mapk8 Positive_regulation of Jun 3 0.40 2.69 0.58
174 INT73654 Binding of Jun and Pim3 1 0.02 0.99 0.58
175 INT109065 Pdyn Positive_regulation of Gene_expression of Gata4 1 0.00 0 0.58
176 INT107523 Negative_regulation of Grm5 Negative_regulation of Gene_expression of Fos 1 0.37 0.09 0.58
177 INT213727 Ngf Regulation of Gene_expression of Fos 1 0.21 0.27 0.58
178 INT128603 Il1b Positive_regulation of Gene_expression of Fos 1 0.50 0.59 0.58
179 INT93063 Binding of gr and Jun 3 0.14 0.79 0.57
180 INT90115 Ntrk2 Regulation of Jun 1 0.01 0.27 0.57
181 INT11280 Fos Regulation of Transcription of Penk 1 0.04 0.55 0.57
182 INT333476 IL12B Positive_regulation of Localization of AFP 1 0.03 0.26 0.57
183 INT76248 Tac1 Positive_regulation of Gene_expression of Fos 1 0.34 0.34 0.56
184 INT87613 LMOD1 Positive_regulation of Fos 1 0.00 0.15 0.56
185 INT51568 Acyp2-ps1 Positive_regulation of Positive_regulation of Fos 1 0.35 0.19 0.56
186 INT253835 Binding of DST and Fos 1 0.02 0 0.55
187 INT105421 Fos Positive_regulation of Gene_expression of Penk 1 0.54 0 0.55
188 INT118513 Par2 Positive_regulation of Gene_expression of Fos 1 0.19 0.23 0.54
189 INT343913 Binding of FOS and Smad3 1 0.19 0.92 0.54
190 INT137246 Slc6a14 Negative_regulation of Gene_expression of Fos 1 0.10 1.24 0.54
191 INT253832 Binding of Fos and Nts 1 0.14 0 0.54
192 INT271902 Binding of KCNK1 and Jun 1 0.12 0.08 0.53
193 INT247265 Mecp2 Regulation of Fos 1 0.25 0.38 0.52
194 INT114647 Fos Positive_regulation of Gene_expression of PDYN 1 0.48 0.52 0.52
195 INT119546 Nfe2l2 Regulation of Gene_expression of Fos 1 0.48 0.94 0.52
196 INT98684 Tac2 Positive_regulation of Gene_expression of Fos 1 0.12 0.16 0.51
197 INT143939 Il1b Regulation of Gene_expression of Fos 1 0.10 0.44 0.49
198 INT90131 NOS1 Regulation of Fos 1 0.00 0.25 0.49
199 INT90121 Nos1 Regulation of Fos 1 0.27 0.25 0.49
200 INT121840 Sct Positive_regulation of Gene_expression of Fos 1 0.61 0 0.48

Single Events

The table below shows the top 100 pain related interactions that have been reported for SMAD protein signal transduction. They are ordered first by their pain relevance and then by number of times they were reported in SMAD protein signal transduction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02
2 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684
3 INT5228 Positive_regulation of Fos 934 0.70 209.8 503.87
4 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84
5 INT5379 Gene_expression of Fos 656 0.78 255.5 292.54
6 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78
7 INT6665 Gene_expression of FOS 520 0.77 165.31 217.66
8 INT5380 Positive_regulation of Gene_expression of Fos 243 0.70 105.65 131.05
9 INT5587 Regulation of Fos 191 0.62 40.81 99.7
10 INT7944 Positive_regulation of Fos 193 0.70 60.69 98.31
11 INT17459 Positive_regulation of Gene_expression of FOS 182 0.67 53.45 96.38
12 INT5590 Negative_regulation of Fos 144 0.59 40.94 81.98
13 INT9484 Gene_expression of Jun 175 0.78 34.89 68.54
14 INT6436 Positive_regulation of Positive_regulation of Fos 101 0.70 18.71 57.96
15 INT6669 Negative_regulation of Positive_regulation of Fos 98 0.59 23.5 56.82
16 INT5356 Positive_regulation of FOS 153 0.69 54.21 56.74
17 INT17458 Negative_regulation of Gene_expression of FOS 98 0.57 36.77 55.69
18 INT8528 Negative_regulation of Gene_expression of Fos 100 0.59 41.15 55.6
19 INT6796 Positive_regulation of Jun 165 0.70 37.18 49.64
20 INT666 Gene_expression of Jun 124 0.78 54.61 33.67
21 INT6053 Transcription of Fos 107 0.72 20.97 31.88
22 INT47764 Binding of Jun 106 0.48 22.62 31.39
23 INT6058 Localization of Fos 73 0.81 16.7 30.84
24 INT6660 Positive_regulation of Jun 148 0.69 67.58 29.73
25 INT17331 Positive_regulation of JUN 132 0.69 60.4 27.03
26 INT5378 Regulation of Gene_expression of Fos 47 0.60 14.47 26.41
27 INT48979 Regulation of Gene_expression of FOS 52 0.61 14.4 25.95
28 INT19949 Regulation of Positive_regulation of Fos 36 0.60 6.11 22.05
29 INT5586 Binding of Fos 47 0.48 12.7 21.33
30 INT9482 Positive_regulation of Gene_expression of Jun 60 0.69 9.95 18.61
31 INT11275 Regulation of Fos 37 0.60 5.79 18.18
32 INT8526 Negative_regulation of Positive_regulation of Fos 26 0.59 5.99 17.52
33 INT60197 Gene_expression of JUN 90 0.78 42.32 14.61
34 INT17593 Regulation of Jun 37 0.60 5.5 14.35
35 INT6794 Negative_regulation of Jun 37 0.53 8.04 13.37
36 INT15246 Regulation of FOS 32 0.60 15.34 12.94
37 INT15756 Positive_regulation of Gene_expression of Jun 29 0.69 16.58 12.06
38 INT6051 Positive_regulation of Transcription of Fos 27 0.69 6.3 11.48
39 INT70816 Negative_regulation of Fos 32 0.58 13 11.18
40 INT52233 Transcription of Jun 37 0.66 6.39 11.15
41 INT15597 Negative_regulation of Gene_expression of Jun 20 0.48 6.04 11.08
42 INT52657 Phosphorylation of Fos 20 0.80 6.36 10.64
43 INT60198 Binding of JUN 54 0.48 11.56 10.27
44 INT17592 Positive_regulation of Regulation of Fos 21 0.67 3.54 10.07
45 INT8527 Positive_regulation of Positive_regulation of Fos 20 0.70 6.87 9.62
46 INT6510 Gene_expression of AFP 130 0.78 119.2 9.19
47 INT48978 Negative_regulation of FOS 41 0.57 11.94 9.14
48 INT61264 Regulation of Jun 36 0.61 18.42 8.71
49 INT47769 Phosphorylation of Fos 20 0.61 3.03 8.68
50 INT64815 Binding of Jun 49 0.48 21.47 8.59
51 INT17333 Positive_regulation of Positive_regulation of FOS 17 0.67 6.06 8.4
52 INT53975 Positive_regulation of Binding of Jun 28 0.70 4.67 8.16
53 INT8669 Positive_regulation of Afp 66 0.70 58.21 7.67
54 INT64816 Transcription of Jun 31 0.69 16.01 7.64
55 INT47848 Negative_regulation of Positive_regulation of FOS 14 0.57 3.78 7.63
56 INT9476 Regulation of Gene_expression of Jun 14 0.43 4.25 7.61
57 INT10344 Localization of Jun 23 0.73 6.36 7.46
58 INT6511 Positive_regulation of AFP 76 0.70 70.15 7.28
59 INT75497 Regulation of JUN 28 0.61 11.04 7.09
60 INT60196 Binding of FOS 33 0.47 13.11 6.95
61 INT53491 Negative_regulation of Jun 28 0.57 14.2 6.9
62 INT47817 Positive_regulation of Positive_regulation of Jun 21 0.66 3.7 6.83
63 INT68653 Negative_regulation of JUN 34 0.58 14.27 6.56
64 INT5847 Transcription of FOS 31 0.69 11.11 6.41
65 INT47765 Negative_regulation of Binding of Jun 21 0.43 5.05 6.38
66 INT73649 Phosphorylation of Jun 28 0.80 11.01 5.87
67 INT8525 Regulation of Positive_regulation of Fos 9 0.60 4.04 5.75
68 INT93484 Negative_regulation of Positive_regulation of Jun 30 0.58 9.31 5.18
69 INT106524 Phosphorylation of Jun 23 0.80 15.35 4.78
70 INT204449 Gene_expression of T 17 0.32 9.77 4.77
71 INT12194 Gene_expression of Trf 38 0.69 18.1 4.56
72 INT54911 Localization of FOS 20 0.78 3.27 4.56
73 INT47766 Transcription of Fos 25 0.69 8.78 4.42
74 INT11565 Gene_expression of Tf 24 0.68 5.89 4.36
75 INT745 Gene_expression of Afp 65 0.78 52.89 4.24
76 INT11277 Localization of Fos 22 0.78 6.58 4.19
77 INT67936 Transcription of JUN 18 0.52 9.52 4.13
78 INT64163 Negative_regulation of Gene_expression of Jun 13 0.58 3.86 4.03
79 INT10808 Negative_regulation of Negative_regulation of Fos 3 0.57 1.08 3.92
80 INT6661 Positive_regulation of Positive_regulation of Jun 31 0.50 7.12 3.89
81 INT60924 Regulation of Regulation of Fos 6 0.44 1.04 3.89
82 INT110180 Phosphorylation of JUN 23 0.80 11.21 3.83
83 INT64817 Positive_regulation of Binding of Jun 16 0.69 6.78 3.81
84 INT84232 Negative_regulation of Transcription of Fos 9 0.58 1.84 3.78
85 INT25251 Binding of Fos 19 0.36 7.96 3.73
86 INT15776 Localization of Jun 10 0.74 3.9 3.69
87 INT61570 Positive_regulation of Transcription of Jun 10 0.35 1.62 3.45
88 INT141148 Gene_expression of BMP7 24 0.71 14.34 3.44
89 INT100295 Gene_expression of Bmp7 27 0.78 14.34 3.3
90 INT81453 Positive_regulation of Gene_expression of JUN 18 0.50 9.39 3.23
91 INT70387 Negative_regulation of Positive_regulation of Jun 14 0.37 3.76 3.23
92 INT50616 Positive_regulation of Regulation of Fos 4 0.49 0.72 3.17
93 INT169113 Negative_regulation of Phosphorylation of Fos 1 0.42 2.17 3.12
94 INT47768 Positive_regulation of Phosphorylation of Fos 6 0.11 0 3.11
95 INT8477 Negative_regulation of AFP 35 0.58 31.52 3.1
96 INT85809 Gene_expression of BMP2 46 0.78 9.91 3.05
97 INT39990 Negative_regulation of BMP6 1 0.59 0 3.05
98 INT68651 Negative_regulation of Positive_regulation of JUN 11 0.58 4.28 3.04
99 INT96423 Gene_expression of Bmp2 61 0.78 25.07 3.01
100 INT48605 Positive_regulation of Localization of Fos 4 0.49 1.26 2.94
101 INT46650 Localization of Trf 13 0.61 4.4 2.91
102 INT8670 Negative_regulation of Afp 27 0.58 19.85 2.87
103 INT108358 Phosphorylation of FOS 12 0.80 6.33 2.79
104 INT64819 Positive_regulation of Transcription of Jun 6 0.50 4.41 2.79
105 INT61096 Negative_regulation of Regulation of Fos 5 0.42 2.12 2.77
106 INT47770 Positive_regulation of Transcription of Fos 9 0.49 1.87 2.71
107 INT17033 Positive_regulation of Trf 21 0.62 11.76 2.68
108 INT60750 Gene_expression of HNF4A 12 0.65 8.29 2.68
109 INT194495 Regulation of Transcription of Jun 4 0.26 2.85 2.6
110 INT109378 Regulation of Phosphorylation of Fos 3 0.26 1.61 2.45
111 INT123682 Localization of JUN 8 0.50 4.15 2.38
112 INT61029 Positive_regulation of Binding of Fos 3 0.49 0.82 2.38
113 INT48980 Positive_regulation of Transcription of FOS 10 0.67 3.07 2.34
114 INT60199 Positive_regulation of Binding of JUN 5 0.49 1.3 2.34
115 INT50992 Regulation of Negative_regulation of Fos 2 0.26 0.73 2.22
116 INT53981 Regulation of Binding of Jun 5 0.44 0.63 2.12
117 INT59358 Regulation of Gene_expression of Jun 10 0.61 3.7 2.11
118 INT79020 Regulation of Binding of Fos 3 0.45 1.2 2.1
119 INT53434 Positive_regulation of T 7 0.07 3.67 2.09
120 INT110925 Positive_regulation of Positive_regulation of JUN 14 0.49 6.22 1.98
121 INT92522 Regulation of Regulation of Fos 3 0.23 0.25 1.98
122 INT83329 Regulation of Gene_expression of Tf 4 0.16 1.83 1.93
123 INT107178 Gene_expression of Smad4 12 0.65 9.85 1.92
124 INT130208 Positive_regulation of Phosphorylation of JUN 4 0.38 3.07 1.92
125 INT53982 Regulation of Positive_regulation of Jun 4 0.54 0.9 1.89
126 INT36499 Negative_regulation of Tf 6 0.38 3.02 1.85
127 INT120088 Gene_expression of Bmp4 37 0.73 13.89 1.73
128 INT89871 Gene_expression of Gata4 11 0.69 1.05 1.53
129 INT14971 Regulation of Afp 12 0.44 11.35 1.48
130 INT121970 Negative_regulation of Transcription of Fos 4 0.42 2.52 1.48
131 INT171029 Positive_regulation of Transcription of JUN 4 0.14 2.87 1.48
132 INT97560 Regulation of Transcription of Fos 6 0.44 2.71 1.46
133 INT130014 Positive_regulation of BMP2 11 0.66 5.34 1.42
134 INT5588 Positive_regulation of Negative_regulation of Fos 3 0.49 0.68 1.42
135 INT106142 Positive_regulation of Phosphorylation of Fos 4 0.49 0.71 1.4
136 INT165538 Binding of Bmp7 5 0.37 1.87 1.39
137 INT287241 Positive_regulation of BMP7 10 0.43 2.68 1.38
138 INT96063 Positive_regulation of Phosphorylation of Jun 7 0.67 4.06 1.38
139 INT90528 Negative_regulation of Binding of Fos 4 0.41 0.25 1.36
140 INT16239 Negative_regulation of Trf 9 0.32 4.06 1.35
141 INT47767 Negative_regulation of Phosphorylation of Fos 3 0.42 0.86 1.3
142 INT70619 Regulation of Bmp2 6 0.60 3.1 1.29
143 INT160606 Localization of AFP 6 0.74 3.39 1.29
144 INT36500 Negative_regulation of Gene_expression of Tf 4 0.38 1.22 1.29
145 INT52212 Gene_expression of Bmp6 6 0.64 2.38 1.27
146 INT68652 Regulation of Positive_regulation of JUN 4 0.54 4.95 1.26
147 INT39991 Negative_regulation of Negative_regulation of BMP6 1 0.43 0 1.24
148 INT120764 Negative_regulation of Binding of JUN 7 0.25 2.65 1.23
149 INT172630 Binding of HNF4A 16 0.05 7.78 1.22
150 INT36443 Regulation of Trf 4 0.61 1.65 1.18
151 INT769 Regulation of Tf 3 0.30 1 1.18
152 INT226407 Negative_regulation of T 2 0.21 1.81 1.18
153 INT64818 Regulation of Binding of Jun 3 0.33 1.06 1.17
154 INT17332 Regulation of Positive_regulation of FOS 6 0.44 0.78 1.11
155 INT75503 Regulation of Gene_expression of JUN 6 0.21 2.87 1.11
156 INT96424 Transcription of Bmp2 6 0.69 6.34 1.11
157 INT69394 Positive_regulation of Binding of FOS 6 0.49 3.54 1.11
158 INT48982 Positive_regulation of Regulation of FOS 2 0.45 0.15 1.11
159 INT208427 Regulation of T 3 0.25 3.28 1.08
160 INT160538 Binding of Bmp2 4 0.40 2.08 1.07
161 INT50409 Regulation of Localization of Fos 3 0.44 0.2 1.07
162 INT172616 Regulation of HNF4A 9 0.06 4.25 1.02
163 INT109069 Transcription of Gata4 4 0.64 0.52 1.01
164 INT109070 Positive_regulation of Transcription of Gata4 1 0.03 0 1.01
165 INT3568 Localization of Tf 4 0.62 1.27 1
166 INT155467 Negative_regulation of Regulation of Fos 1 0.42 1.18 0.96
167 INT52213 Regulation of Localization of Bmp6 1 0.44 0.39 0.93
168 INT114664 Binding of BMP2 12 0.37 6.54 0.91
169 INT52215 Localization of Bmp6 1 0.73 0.37 0.88
170 INT142122 Regulation of Gene_expression of Bmp4 5 0.43 2.69 0.86
171 INT287093 Positive_regulation of Gene_expression of T 1 0.28 1.47 0.86
172 INT287090 Regulation of Gene_expression of T 1 0.18 2.77 0.86
173 INT39357 Binding of Afp 5 0.48 3.58 0.85
174 INT89368 Positive_regulation of Tf 7 0.34 3.62 0.83
175 INT53978 Regulation of Regulation of Jun 4 0.38 0.18 0.83
176 INT66061 Positive_regulation of Gene_expression of AFP 6 0.70 8.67 0.81
177 INT210247 Positive_regulation of Bmp4 6 0.65 4.36 0.8
178 INT287094 Transcription of T 1 0.29 1.41 0.8
179 INT88179 Negative_regulation of Transcription of FOS 3 0.41 0.96 0.78
180 INT141150 Localization of BMP7 4 0.56 2.84 0.76
181 INT106523 Positive_regulation of Phosphorylation of Jun 7 0.45 3.1 0.74
182 INT124739 Negative_regulation of Binding of Jun 2 0.40 1.45 0.74
183 INT172960 Negative_regulation of Gene_expression of Smad4 7 0.39 5.88 0.71
184 INT41928 Binding of AFP 9 0.36 7.85 0.7
185 INT14973 Regulation of Gene_expression of AFP 3 0.44 4.16 0.69
186 INT226411 Binding of T 2 0.15 1.56 0.68
187 INT154019 Protein_catabolism of Jun 2 0.61 0.07 0.67
188 INT138479 Protein_catabolism of Fos 2 0.86 0.67 0.67
189 INT303710 Negative_regulation of Transcription of JUN 1 0.06 0.84 0.65
190 INT96422 Gene_expression of Bmp4 18 0.69 3.26 0.63
191 INT39994 Positive_regulation of BMP6 1 0.50 0 0.63
192 INT39992 Positive_regulation of Negative_regulation of BMP6 1 0.47 0 0.62
193 INT100294 Positive_regulation of Gene_expression of Bmp7 8 0.46 5.41 0.61
194 INT307186 Negative_regulation of Phosphorylation of Jun 4 0.10 2.91 0.61
195 INT89867 Negative_regulation of Gene_expression of Gata4 3 0.38 0.17 0.61
196 INT127262 Negative_regulation of Transcription of Jun 1 0.30 0.52 0.61
197 INT39993 Regulation of BMP6 2 0.39 0.29 0.6
198 INT238049 Positive_regulation of Gene_expression of BMP2 8 0.51 2.06 0.59
199 INT123681 Positive_regulation of Localization of JUN 2 0.25 1.3 0.59
200 INT89126 Regulation of BMP7 7 0.45 2.5 0.58
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