GO:0060412

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Name ventricular septum morphogenesis
Categary Process
Go Slim No
Go Link GO:0060412
Unique Molecular Interactions 46
Total Molecular Interactions 51
Total Single Events 306
Pain Genes Associated 12

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for ventricular septum morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported for ventricular septum morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT89878 Pdyn Positive_regulation of Gene_expression of Nkx2-5 1 0.35 0 1.29
2 INT154236 Binding of TBX3 and Ugt2b7 1 0.41 0.74 1
3 INT89877 Pdyn Positive_regulation of Nkx2-5 1 0.11 0 0.64
4 INT291616 Cby1 Positive_regulation of Gene_expression of Smad7 1 0.00 0.79 0.38
5 INT109067 Pdyn Positive_regulation of Gene_expression of NKX2-5 1 0.01 0 0.29
6 INT208938 Positive_regulation of Tacr1 Positive_regulation of Nkx2-5 1 0.17 0 0.1
7 INT228808 Smad7 Regulation of Rgs1 1 0.19 0.24 0.09
8 INT228812 Smad7 Regulation of Stap1 1 0.00 0.24 0.09
9 INT134837 TGFB1 Regulation of SMAD7 1 0.34 0.68 0.08
10 INT208943 Nfkb1 Positive_regulation of Nkx2-5 1 0.11 0.38 0.08
11 INT134833 TGFB1 Regulation of Gene_expression of SMAD7 1 0.34 0.69 0.08
12 INT134838 TGFB1 Positive_regulation of SMAD7 1 0.52 0.79 0.08
13 INT333847 Binding of E2f5 and Mir17 1 0.03 0.52 0.05
14 INT333849 Binding of Mcm4 and Mir17 1 0.03 0.52 0.05
15 INT333846 Binding of Wee1 and Mir17 1 0.03 0.52 0.05
16 INT333840 Binding of Cables1 and Mir17 1 0.03 0.52 0.05
17 INT333851 Binding of Ccna1 and Mir17 1 0.04 0.52 0.05
18 INT208945 Nkx2-5 Positive_regulation of Gene_expression of Nppa 1 0.03 0.33 0.05
19 INT333841 Binding of Rad51 and Mir17 1 0.02 0.52 0.05
20 INT305383 Binding of NKX2-5 and FLNA 1 0.10 0.7 0.04
21 INT353287 Prdx2 Positive_regulation of Phosphorylation of Smad7 1 0.22 0.06 0.03
22 INT353291 Prdx2 Positive_regulation of Smad7 1 0.31 0.06 0.03
23 INT353288 Smad7 Negative_regulation of Phosphorylation of Tgif1 1 0.08 0.06 0.03
24 INT120077 Gene_expression of Smad7 Negative_regulation of Positive_regulation of Itk 1 0.02 0.27 0
25 INT189554 Binding of HIF1A and Positive_regulation of EGLN1 1 0.04 0.86 0
26 INT274435 Binding of Zfpm2 and Mir130a 1 0.30 0.26 0
27 INT314692 Binding of TBX2 and TBX3 1 0.27 0.84 0
28 INT189555 EGLN1 Regulation of Gene_expression of VEGFA 1 0.07 0.57 0
29 INT218663 Olr811 Positive_regulation of Gene_expression of Smad7 1 0.01 0.45 0
30 INT134836 Binding of SMAD7 and YAP1 1 0.53 0.89 0
31 INT233520 Tlr4 Positive_regulation of Fzd1 1 0.03 0.09 0
32 INT314862 Binding of Ltbp3 and Tgfb2 1 0.24 0.52 0
33 INT274432 Mir130a Regulation of Zfpm2 1 0.22 0.08 0
34 INT274431 Mir130a Regulation of Gene_expression of Zfpm2 1 0.50 0.79 0
35 INT310188 Binding of Adcyap1r1 and Smad7 1 0.00 0 0
36 INT189552 EGLN1 Positive_regulation of HIF1A 1 0.05 0.98 0
37 INT347155 Mirlet7a-1 Negative_regulation of Smad7 1 0.10 0 0
38 INT274434 Binding of Gata4 and Zfpm2 1 0.12 0.56 0
39 INT242165 Wnt2 Positive_regulation of Gene_expression of Fzd1 1 0.15 0.26 0
40 INT272520 Gene_expression of Dmpk Positive_regulation of Positive_regulation of Nkx2-5 1 0.02 0.43 0
41 INT274433 Binding of Zfpm2 and Uts2r 1 0.08 0.17 0
42 INT242166 Fzd1 Positive_regulation of Positive_regulation of Wnt2 1 0.13 0.24 0
43 INT274436 Mir130a Regulation of Transcription of Zfpm2 1 0.22 0 0
44 INT272521 Binding of DMPK and Nkx2-5 1 0.01 0.42 0
45 INT283711 Sox11 Regulation of 4930579C15Rik 1 0.28 0.74 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for ventricular septum morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported in ventricular septum morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT120072 Gene_expression of Smad7 38 0.74 20.87 3.69
2 INT174924 Gene_expression of Smad7 6 0.41 3.59 1.76
3 INT174923 Positive_regulation of Gene_expression of Smad7 3 0.37 2.3 1.73
4 INT89865 Gene_expression of Nkx2-5 14 0.75 2.99 1.58
5 INT120076 Positive_regulation of Gene_expression of Smad7 16 0.65 11.33 1.25
6 INT161716 Localization of Nkx2-5 2 0.74 2.17 1.02
7 INT109075 Positive_regulation of Transcription of NKX2-5 1 0.67 0 1.02
8 INT109074 Transcription of NKX2-5 1 0.69 0 1.01
9 INT109062 Gene_expression of NKX2-5 7 0.75 3.31 0.82
10 INT93737 Gene_expression of Tgfb2 2 0.03 1.16 0.77
11 INT93736 Positive_regulation of Gene_expression of Tgfb2 2 0.02 1.16 0.77
12 INT272878 Negative_regulation of Smad7 4 0.41 3.86 0.72
13 INT89861 Negative_regulation of Nkx2-5 3 0.19 0.12 0.63
14 INT89869 Negative_regulation of Gene_expression of Nkx2-5 1 0.41 0 0.56
15 INT120074 Regulation of Gene_expression of Smad7 1 0.58 2.05 0.5
16 INT305390 Negative_regulation of NKX2-5 2 0.37 2.24 0.49
17 INT224538 Negative_regulation of Gene_expression of Smad7 1 0.09 0.25 0.43
18 INT248931 Positive_regulation of Tgfb2 1 0.03 0 0.4
19 INT283698 Gene_expression of Sox11 1 0.68 4.6 0.33
20 INT134840 Gene_expression of SMAD7 1 0.74 2.74 0.31
21 INT184716 Binding of Smad7 2 0.34 0.91 0.29
22 INT272890 Regulation of Negative_regulation of Smad7 1 0.19 1.33 0.29
23 INT164226 Regulation of TBX3 1 0.23 0.57 0.26
24 INT208915 Positive_regulation of Nkx2-5 3 0.29 1.02 0.25
25 INT181914 Positive_regulation of EGLN1 1 0.36 2.03 0.25
26 INT228793 Negative_regulation of Gene_expression of Smad7 5 0.25 2.33 0.23
27 INT242141 Gene_expression of Fzd1 1 0.21 2.5 0.21
28 INT305392 Binding of NKX2-5 1 0.22 0.93 0.21
29 INT208925 Positive_regulation of Localization of Nkx2-5 1 0.21 0.14 0.16
30 INT228790 Positive_regulation of Smad7 4 0.41 0.58 0.15
31 INT146415 Regulation of Nkx2-5 3 0.44 0.91 0.13
32 INT189614 Gene_expression of EGLN1 6 0.49 4.3 0.12
33 INT208922 Transcription of Nkx2-5 2 0.29 0.36 0.1
34 INT323415 Regulation of NKX2-5 1 0.39 0.71 0.1
35 INT208917 Positive_regulation of Transcription of Nkx2-5 1 0.21 0 0.1
36 INT323416 Localization of NKX2-5 1 0.65 1.75 0.1
37 INT208918 Positive_regulation of Gene_expression of Nkx2-5 3 0.23 0.48 0.09
38 INT283695 Binding of Sox11 1 0.32 0.18 0.08
39 INT353267 Negative_regulation of Positive_regulation of Smad7 1 0.25 0.32 0.08
40 INT233462 Regulation of Fzd1 1 0.45 0.33 0.08
41 INT305387 Positive_regulation of Gene_expression of NKX2-5 1 0.31 0.72 0.07
42 INT251229 Negative_regulation of Tgfb2 1 0.34 0.06 0.07
43 INT158616 Localization of EGLN1 1 0.73 0.54 0.06
44 INT347149 Localization of Smad7 1 0.67 0 0.05
45 INT283696 Localization of Sox11 1 0.65 0.37 0.05
46 INT333799 Gene_expression of Mir17 1 0.12 0.32 0.03
47 INT350515 Transcription of SMAD7 1 0.07 0.38 0.03
48 INT353280 Phosphorylation of Smad7 1 0.48 0.06 0.03
49 INT274420 Positive_regulation of Gene_expression of Zfpm2 1 0.49 0.51 0
50 INT189577 Negative_regulation of EGLN1 1 0.31 1.73 0
51 INT314821 Binding of Tgfb2 1 0.36 0.51 0
52 INT189603 Negative_regulation of Transcription of EGLN1 1 0.31 0.94 0
53 INT352836 Transcription of Mir17 1 0.04 0 0
54 INT283699 Positive_regulation of Sox11 1 0.35 0.62 0
55 INT320726 Negative_regulation of Gene_expression of TBX3 1 0.16 0.66 0
56 INT347148 Regulation of Smad7 1 0.26 0 0
57 INT274412 Transcription of Zfpm2 1 0.53 0 0
58 INT274418 Regulation of Gene_expression of Zfpm2 1 0.45 1.42 0
59 INT320733 Negative_regulation of TBX3 1 0.16 0.66 0
60 INT274417 Negative_regulation of Zfpm2 1 0.43 6.99 0
61 INT274428 Regulation of Binding of Zfpm2 1 0.45 0.15 0
62 INT218701 Negative_regulation of Binding of Smad7 1 0.14 0.15 0
63 INT166121 Binding of SMAD7 1 0.30 0.39 0
64 INT274405 Gene_expression of Zfpm2 1 0.77 6.51 0
65 INT353273 Negative_regulation of Phosphorylation of Smad7 1 0.25 0 0
66 INT320727 Positive_regulation of TBX3 1 0.19 0.84 0
67 INT242143 Regulation of Gene_expression of Fzd1 1 0.14 0.25 0
68 INT274425 Negative_regulation of Gene_expression of Zfpm2 1 0.42 0.06 0
69 INT236702 Positive_regulation of Mir17 1 0.06 0.52 0
70 INT274411 Positive_regulation of Zfpm2 1 0.46 0.53 0
71 INT189605 Regulation of EGLN1 1 0.33 1.65 0
72 INT189617 Transcription of EGLN1 1 0.50 0.94 0
73 INT347145 Transcription of Smad7 1 0.68 0 0
74 INT233478 Negative_regulation of Fzd1 1 0.31 0.09 0
75 INT320720 Gene_expression of TBX3 1 0.29 3.53 0
76 INT274414 Regulation of Zfpm2 1 0.61 0.59 0
77 INT189572 Positive_regulation of Gene_expression of EGLN1 1 0.34 0.92 0
78 INT218685 Binding of Smad7 1 0.13 0.15 0
79 INT274408 Binding of Zfpm2 1 0.37 0.77 0
80 INT242126 Positive_regulation of Fzd1 1 0.16 0.25 0
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