GO:0060416

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Name response to growth hormone stimulus
Categary Process
Go Slim No
Go Link GO:0060416
Unique Molecular Interactions 62
Total Molecular Interactions 77
Total Single Events 852
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to growth hormone stimulus. They are ordered first by their pain relevance and then by number of times they were reported for response to growth hormone stimulus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54
2 INT293200 Positive_regulation of Grin1 Positive_regulation of Phosphorylation of Grin2b 1 0.24 0.4 1.39
3 INT122267 Prkcg Positive_regulation of Grin2b 1 0.26 0.61 1.14
4 INT122268 Binding of Grin2b and Grm5 1 0.40 0.52 1.1
5 INT353690 Binding of Grin2b and Ca2 1 0.14 1.17 1.01
6 INT122269 Src Negative_regulation of Positive_regulation of Grin2b 1 0.27 0.44 0.92
7 INT122266 Src Negative_regulation of Grin2b 1 0.27 0.43 0.91
8 INT212290 Binding of Grin2a and Grin2b 2 0.20 1.36 0.82
9 INT186160 Negative_regulation of Grin2b Negative_regulation of Grin1 1 0.37 0.5 0.72
10 INT249485 Trib3 Negative_regulation of Phosphorylation of Grin2b 1 0.02 0.64 0.68
11 INT250084 Negative_regulation of Grin2b Negative_regulation of Positive_regulation of Ltp 1 0.18 0.07 0.66
12 INT249489 Src Negative_regulation of Phosphorylation of Grin2b 1 0.20 0.63 0.66
13 INT250078 Negative_regulation of Grin2b Negative_regulation of Ltp 1 0.18 0.07 0.66
14 INT302441 Binding of GRIN1 and Grin2b 1 0.10 1.27 0.63
15 INT186159 Grin2d Negative_regulation of Grin2b 1 0.21 0.82 0.62
16 INT249484 Trib3 Positive_regulation of Phosphorylation of Grin2b 1 0.01 0.57 0.61
17 INT249497 Efnb2 Positive_regulation of Phosphorylation of Grin2b 1 0.02 0.51 0.54
18 INT249479 Binding of Ephb1 and Grin2b 1 0.29 0.37 0.54
19 INT120852 PRL Positive_regulation of IRF1 1 0.44 0.99 0.51
20 INT250080 Grin2b Positive_regulation of Ltp 1 0.22 0.19 0.49
21 INT120854 IRF1 Positive_regulation of Localization of TNF 1 0.20 0.94 0.49
22 INT249486 Positive_regulation of Ephb1 Positive_regulation of Phosphorylation of Grin2b 1 0.33 0.4 0.46
23 INT105733 Grin2b Negative_regulation of Gene_expression of Grin2a 1 0.22 0.09 0.41
24 INT279620 Negative_regulation of Binding of Grin2a and Grin2b 1 0.18 0.99 0.4
25 INT56876 Regulation of Binding of Cd36 and Gtpbp4 1 0.00 0 0.4
26 INT56875 Binding of Cd36 and Gtpbp4 1 0.00 0 0.4
27 INT84521 Binding of F7 and TF 1 0.06 0.09 0.37
28 INT249492 Trib3 Regulation of Phosphorylation of Grin2b 1 0.01 0.23 0.35
29 INT236006 HTR1A Regulation of Grin2b 1 0.00 0 0.33
30 INT165580 Binding of Akt1 and Grin2b 1 0.02 0.2 0.32
31 INT250079 Grin2b Regulation of Ltp 1 0.18 0.31 0.29
32 INT247081 Binding of F5 and F7 1 0.00 0.87 0.28
33 INT249493 Binding of Grin2b and Src 1 0.17 0.15 0.26
34 INT120853 PRL Positive_regulation of Positive_regulation of IRF1 1 0.41 0.49 0.25
35 INT250074 Grin2b Positive_regulation of Gene_expression of Hpcal4 1 0.04 0.3 0.2
36 INT198382 Binding of AR and SRD5A1 2 0.06 0.84 0.17
37 INT247084 Binding of F7 and H1F0 1 0.00 0.38 0.17
38 INT343863 Binding of IRF1 and IRF3 1 0.03 0.12 0.17
39 INT281319 Binding of F7 and tf 1 0.24 1 0.16
40 INT186357 Binding of Irf1 and Stat6 1 0.04 2.09 0.14
41 INT186372 Binding of Irf1 and Stat1 1 0.04 2.06 0.14
42 INT249495 Binding of Grin2b and Efnb2 1 0.02 0.05 0.11
43 INT301613 Binding of Fabp4 and Cd36 1 0.05 0.38 0.08
44 INT301614 Binding of Slc27a1 and Cd36 1 0.09 0.38 0.08
45 INT186361 Binding of Gast and Irf1 1 0.01 1.03 0.07
46 INT186341 Binding of Irf1 and Irf2 1 0.02 1.04 0.07
47 INT186390 Binding of TNF and Irf1 1 0.02 0.99 0.05
48 INT250073 Grin2a Regulation of Grin2b 1 0.39 0.9 0.05
49 INT186377 Binding of Irf1 and GORASP1 1 0.12 0.87 0.05
50 INT186348 Irf1 Regulation of Positive_regulation of Nos2 1 0.02 0.91 0.04
51 INT229008 MIA3 Positive_regulation of Gene_expression of Cd36 1 0.02 0.49 0.03
52 INT191182 Binding of IRF1 and PRPF31 1 0.06 0.09 0.03
53 INT283630 Cd36 Regulation of Positive_regulation of Ie 1 0.00 0 0
54 INT186346 Binding of Irf8 and Irf1 1 0.05 1.25 0
55 INT313271 Binding of GRIN1 and GRIN2B 1 0.24 0.06 0
56 INT169858 Grin1 Regulation of Gene_expression of Grin2b 1 0.42 0 0
57 INT186343 Irf1 Positive_regulation of Nos2 1 0.04 0.83 0
58 INT283631 Positive_regulation of Binding of Cd36 and Ie 1 0.00 0 0
59 INT186365 Vcam1 Regulation of Binding of Irf1 1 0.05 0.83 0
60 INT186370 Regulation of Binding of Irf8 and Irf1 1 0.04 0.82 0
61 INT169856 Grin1 Positive_regulation of Grin2b 1 0.46 0 0
62 INT283629 Binding of Cd36 and Ie 1 0.00 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to growth hormone stimulus. They are ordered first by their pain relevance and then by number of times they were reported in response to growth hormone stimulus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT104000 Phosphorylation of Grin2b 73 0.82 48.34 93.48
2 INT79506 Gene_expression of Grin2b 122 0.78 43.71 73.42
3 INT82054 Positive_regulation of Grin2b 56 0.70 17.45 37.14
4 INT103998 Positive_regulation of Phosphorylation of Grin2b 33 0.69 19.08 36.08
5 INT93033 Negative_regulation of Grin2b 48 0.58 20.94 28.54
6 INT102281 Positive_regulation of Gene_expression of Grin2b 27 0.70 10.38 20.84
7 INT93037 Regulation of Grin2b 26 0.57 11.9 16.92
8 INT103996 Negative_regulation of Phosphorylation of Grin2b 11 0.58 7.81 12.85
9 INT122117 Negative_regulation of Gene_expression of Grin2b 20 0.59 11.3 12.55
10 INT80006 Regulation of Gene_expression of Grin2b 8 0.57 3.75 9.62
11 INT95342 Gene_expression of GRIN2B 21 0.75 4.99 9.32
12 INT99495 Gene_expression of SRD5A1 14 0.77 5 9.21
13 INT100658 Negative_regulation of Positive_regulation of Grin2b 7 0.41 1.39 6.17
14 INT74593 Transcription of Grin2b 10 0.66 1.21 5.98
15 INT127353 Regulation of Phosphorylation of Grin2b 5 0.45 1.6 5.29
16 INT92541 Localization of Grin2b 11 0.75 2.85 5.14
17 INT79505 Binding of Grin2b 9 0.36 1.43 4.61
18 INT118583 Positive_regulation of IRF1 10 0.68 3.75 3.91
19 INT99889 Transcription of SRD5A1 5 0.71 1.45 3.74
20 INT16616 Negative_regulation of SRD5A1 44 0.57 34.81 2.96
21 INT101055 Regulation of GRIN2B 4 0.61 1.39 2.5
22 INT9840 Positive_regulation of F7 17 0.57 17.83 2.08
23 INT342815 Positive_regulation of Transcription of SRD5A1 1 0.49 0.33 2.04
24 INT118884 Gene_expression of IRF1 5 0.66 2.71 2
25 INT151942 Regulation of Negative_regulation of Grin2b 2 0.41 0.41 1.92
26 INT118882 Positive_regulation of Gene_expression of IRF1 1 0.49 1.35 1.92
27 INT74594 Regulation of Transcription of Grin2b 1 0.42 0.17 1.8
28 INT130440 Phosphorylation of GRIN2B 2 0.79 2.93 1.79
29 INT107379 Localization of GRIN2B 2 0.73 0.86 1.48
30 INT73938 Gene_expression of Cd36 20 0.76 12.27 1.35
31 INT198387 Regulation of SRD5A1 2 0.60 1.29 1.26
32 INT249527 Positive_regulation of Positive_regulation of Grin2b 2 0.37 1.12 1.22
33 INT95347 Negative_regulation of GRIN2B 1 0.57 0 1.19
34 INT154493 Regulation of Gene_expression of SRD5A1 3 0.45 0.58 1.03
35 INT73939 Negative_regulation of Cd36 7 0.57 6.3 0.95
36 INT101056 Positive_regulation of GRIN2B 1 0.23 0.32 0.9
37 INT186168 Negative_regulation of Negative_regulation of Grin2b 2 0.35 0.54 0.85
38 INT165578 Regulation of Positive_regulation of Grin2b 3 0.41 1.07 0.74
39 INT114524 Binding of GRIN2B 3 0.36 0.44 0.74
40 INT107779 Negative_regulation of F7 3 0.30 2.99 0.66
41 INT139895 Positive_regulation of Gene_expression of GRIN2B 2 0.49 0.9 0.65
42 INT186266 Gene_expression of Irf1 4 0.36 3.26 0.64
43 INT122116 Negative_regulation of Transcription of Grin2b 1 0.43 0.34 0.62
44 INT271625 Protein_catabolism of Grin2b 1 0.38 0.26 0.57
45 INT156378 Regulation of Binding of Grin2b 1 0.28 0.17 0.52
46 INT342811 Positive_regulation of Gene_expression of SRD5A1 1 0.45 0.22 0.5
47 INT163895 Positive_regulation of Phosphorylation of GRIN2B 1 0.09 0.99 0.48
48 INT271632 Negative_regulation of Regulation of Grin2b 2 0.28 1.06 0.47
49 INT250065 Positive_regulation of Localization of Grin2b 1 0.45 0 0.47
50 INT280670 Localization of Cd36 1 0.61 0.65 0.41
51 INT280675 Regulation of Localization of Cd36 1 0.32 0.57 0.41
52 INT126571 Positive_regulation of Cd36 3 0.41 1.19 0.38
53 INT200523 Regulation of F7 2 0.01 1.82 0.38
54 INT247095 Binding of F7 2 0.03 1.91 0.37
55 INT271630 Negative_regulation of Localization of Grin2b 1 0.25 0 0.37
56 INT250062 Positive_regulation of Transcription of Grin2b 1 0.39 0.47 0.34
57 INT102992 Regulation of Negative_regulation of SRD5A1 4 0.60 3.59 0.29
58 INT163897 Negative_regulation of Phosphorylation of GRIN2B 1 0.08 0.39 0.28
59 INT271629 Positive_regulation of Protein_catabolism of Grin2b 1 0.27 0.13 0.28
60 INT126794 Binding of SRD5A1 2 0.36 3.26 0.22
61 INT221999 Gene_expression of F7 2 0.65 2.1 0.2
62 INT287790 Positive_regulation of Gene_expression of F7 1 0.49 1.55 0.2
63 INT186278 Binding of Irf1 7 0.16 3.99 0.19
64 INT186305 Positive_regulation of Gene_expression of Irf1 2 0.17 1.24 0.18
65 INT343899 Localization of IRF1 1 0.23 0.12 0.17
66 INT295243 Regulation of Irf1 1 0.16 0.46 0.15
67 INT236875 Localization of SRD5A1 2 0.73 0.8 0.11
68 INT129458 Regulation of Localization of F7 1 0.19 0.33 0.08
69 INT129459 Localization of F7 1 0.31 0.33 0.08
70 INT186289 Negative_regulation of Gene_expression of Irf1 1 0.10 0.99 0.07
71 INT9843 Negative_regulation of Positive_regulation of F7 1 0.48 0.83 0.06
72 INT236876 Negative_regulation of Localization of SRD5A1 1 0.41 0.81 0.06
73 INT186303 Transcription of Irf1 1 0.16 0.92 0.04
74 INT186280 Positive_regulation of Irf1 1 0.11 0.43 0.03
75 INT272182 Transcription of Cd36 3 0.56 1.45 0
76 INT272181 Positive_regulation of Transcription of Cd36 2 0.41 0.75 0
77 INT280644 Positive_regulation of Gene_expression of Cd36 2 0.49 0.96 0
78 INT178534 Positive_regulation of SRD5A1 2 0.44 1.23 0
79 INT236869 Negative_regulation of Negative_regulation of SRD5A1 2 0.41 2.68 0
80 INT280642 Negative_regulation of Gene_expression of Cd36 1 0.35 0.08 0
81 INT280549 Regulation of Gene_expression of IRF1 1 0.20 0.81 0
82 INT222000 Regulation of Gene_expression of F7 1 0.08 0.76 0
83 INT202320 Protein_catabolism of Cd36 1 0.96 0.3 0
84 INT186291 Localization of Irf1 1 0.17 0.83 0
85 INT222002 Negative_regulation of Gene_expression of F7 1 0.13 0.57 0
86 INT271827 Regulation of Cd36 1 0.18 0.94 0
87 INT256918 Negative_regulation of Irf1 1 0.24 1.71 0
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