GO:0060425

From wiki-pain
Jump to: navigation, search
Name lung morphogenesis
Categary Process
Go Slim No
Go Link GO:0060425
Unique Molecular Interactions 113
Total Molecular Interactions 155
Total Single Events 728
Pain Genes Associated 20

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for lung morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported for lung morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT250867 Fgf8 Positive_regulation of Protein_catabolism of Ecm1 1 0.06 4.35 2.14
2 INT89873 Pdyn Positive_regulation of Gene_expression of Gata4 1 0.23 0 1.29
3 INT89876 Pdyn Positive_regulation of Gata4 1 0.23 0 1.28
4 INT281373 Tcf21 Regulation of Fig4 1 0.03 0.67 1.2
5 INT281379 Tcf21 Regulation of FSCN1 1 0.01 0.66 1.19
6 INT75486 Binding of Tgfbr1 and Tgfbr2 1 0.10 1.94 1.02
7 INT316128 TCF21 Negative_regulation of Gene_expression of HLA-DRA 1 0.07 0.13 0.99
8 INT250868 Fgf8 Positive_regulation of Gene_expression of Mmp3 1 0.15 1.73 0.93
9 INT250861 Fgf8 Positive_regulation of Gene_expression of Ptger2 1 0.04 1.51 0.84
10 INT109065 Pdyn Positive_regulation of Gene_expression of Gata4 1 0.00 0 0.58
11 INT222246 Binding of Ccr2 and Tcf21 1 0.29 0.67 0.55
12 INT222249 Positive_regulation of Binding of Ccr2 and Tcf21 1 0.39 0.67 0.55
13 INT281124 Tcf21 Positive_regulation of Binding of Ddc 1 0.04 1.21 0.54
14 INT250852 Fgf8 Negative_regulation of Gene_expression of Ecm1 1 0.04 1.1 0.54
15 INT281129 Tcf21 Positive_regulation of Binding of Cd4 1 0.04 1.21 0.54
16 INT281152 Tcf21 Positive_regulation of Binding of ITIH4 1 0.03 1.21 0.54
17 INT281131 Tcf21 Positive_regulation of Rent1 1 0.00 1.19 0.53
18 INT171914 MAPK8IP3 Positive_regulation of Gene_expression of MAPK1 1 0.06 1.55 0.52
19 INT281374 Tcf21 Positive_regulation of Gene_expression of Sds 1 0.03 0 0.51
20 INT135751 Pomc Positive_regulation of Positive_regulation of Id1 1 0.19 0 0.5
21 INT135753 Pomc Positive_regulation of Gene_expression of Id1 1 0.17 0 0.5
22 INT135754 Pomc Positive_regulation of Id1 1 0.17 0 0.5
23 INT75489 Binding of SGCG and Tgfbr2 1 0.23 0.83 0.41
24 INT75487 Binding of TGFB1 and Tgfbr2 1 0.31 0.83 0.41
25 INT250870 Fgf8 Positive_regulation of Ecm1 1 0.04 0.79 0.38
26 INT348016 Binding of Mapk8 and Mapk8ip3 1 0.04 2.09 0.32
27 INT222251 Negative_regulation of Binding of Cxcl10 and Tcf21 1 0.23 0.34 0.32
28 INT222247 Binding of Cxcl10 and Tcf21 1 0.20 0.34 0.32
29 INT281127 Tcf21 Positive_regulation of Gene_expression of Cxcr4 1 0.08 0.42 0.3
30 INT250856 Fgf8 Positive_regulation of Localization of Mmp3 1 0.11 0.51 0.3
31 INT250864 Fgf8 Positive_regulation of Positive_regulation of Ptger2 1 0.03 0.55 0.28
32 INT250854 Fgf8 Positive_regulation of Positive_regulation of Mmp3 1 0.11 0.55 0.28
33 INT171912 MAPK8IP3 Positive_regulation of MAPK9 1 0.06 0.78 0.26
34 INT171911 MAPK8IP3 Positive_regulation of Gene_expression of MAPK14 1 0.05 0.77 0.26
35 INT250873 Fgf8 Positive_regulation of GAG 1 0.55 0.48 0.23
36 INT287894 VEGFA Positive_regulation of Localization of BMP4 1 0.04 2.49 0.2
37 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19
38 INT348034 Mapk8ip3 Negative_regulation of Mapk8 1 0.05 0.98 0.16
39 INT348019 Negative_regulation of Binding of Mapk8 and Mapk8ip3 1 0.05 1.04 0.16
40 INT250863 Fgf8 Positive_regulation of Ptger2 1 0.03 0.19 0.14
41 INT65267 Igf1 Regulation of Gene_expression of Plod3 1 0.07 0 0.13
42 INT65271 Igf1 Positive_regulation of Gene_expression of Plod3 1 0.12 0 0.13
43 INT250866 Binding of Fgfr4 and Fgf8 1 0.12 0.35 0.11
44 INT250860 Fgf8 Regulation of Localization of Ptger2 1 0.02 0.13 0.1
45 INT287887 WNT1 Positive_regulation of Localization of BMP4 1 0.04 1.13 0.1
46 INT250862 Fgf8 Regulation of Localization of Mmp3 1 0.13 0.13 0.1
47 INT250859 Fgf8 Negative_regulation of Gene_expression of Mmp3 1 0.09 0.12 0.09
48 INT250872 Fgf8 Positive_regulation of Mmp3 1 0.11 0.12 0.09
49 INT270464 Binding of Shh and Smo 1 0.07 1.3 0.08
50 INT290906 Shh Positive_regulation of Egfr 1 0.23 0 0.08
51 INT343792 Binding of TCF21 and CORO7 1 0.01 0.51 0.07
52 INT298349 HES3 Positive_regulation of Shh 1 0.12 0.14 0.07
53 INT303562 Binding of Fgf10 and Fgfr2 1 0.40 0.88 0.07
54 INT22568 Cyp1a1 Positive_regulation of Tcf21 1 0.04 0 0.06
55 INT290905 Gene_expression of Shh Positive_regulation of Gene_expression of Angpt1 1 0.14 0 0.06
56 INT22567 Cyp1a2 Positive_regulation of Tcf21 1 0.04 0 0.06
57 INT250865 Binding of Fgf8 and Fgfr3 1 0.18 0.3 0.05
58 INT250855 Binding of Fgfr2 and Fgf8 1 0.12 0.3 0.05
59 INT181814 Gsk3b Regulation of Gata4 1 0.06 0.37 0.05
60 INT210261 Bmp4 Regulation of Gene_expression of Tff3 1 0.64 0 0.05
61 INT213563 Binding of Ctnnd2 and Shh 1 0.27 0.09 0.04
62 INT270459 Binding of Shh and Gli1 1 0.02 0.65 0.04
63 INT306560 BMP4 Positive_regulation of MAPK1 1 0.09 0.09 0.03
64 INT352014 Shh Positive_regulation of Gene_expression of Pax1 1 0.29 0.07 0.03
65 INT303563 Binding of Fgf10 and Dysf 1 0.00 0.44 0.03
66 INT311655 Shh Positive_regulation of Gene_expression of Fgf8 1 0.31 0.18 0.03
67 INT270462 Shh Positive_regulation of Ccnd1 1 0.10 0.6 0.03
68 INT213559 Binding of Egf and Shh 1 0.17 0.07 0.03
69 INT290910 Pkm2 Negative_regulation of Shh 1 0.07 0.06 0
70 INT314850 Shh Regulation of Atoh7 1 0.45 0.22 0
71 INT290908 Regulation of Shh Positive_regulation of Ntn1 1 0.12 0 0
72 INT290911 Gene_expression of Shh Positive_regulation of Pkm2 1 0.07 0 0
73 INT310191 Flt3 Positive_regulation of Gene_expression of Id1 1 0.03 0.81 0
74 INT290904 Shh Positive_regulation of Prkcg 1 0.26 0.06 0
75 INT290900 Prkcg Regulation of Shh 1 0.23 0 0
76 INT290944 Shh Positive_regulation of VEGFA 1 0.04 0.05 0
77 INT270461 Shh Regulation of Gene_expression of Ptch1 1 0.48 0.07 0
78 INT196023 Bmp2 Negative_regulation of Gene_expression of Bmp4 1 0.09 0.07 0
79 INT184956 ID1 Negative_regulation of CDKN2A 1 0.42 0.21 0
80 INT274434 Binding of Gata4 and Zfpm2 1 0.12 0.56 0
81 INT196021 Bmp2 Positive_regulation of Gene_expression of Bmp4 1 0.09 0.08 0
82 INT286420 Binding of Fgf13 and Mapk8ip3 1 0.36 0 0
83 INT270471 Shh Regulation of VEGFA 1 0.39 0.08 0
84 INT290898 Shh Positive_regulation of Nos2 1 0.46 0.05 0
85 INT202675 Fgf10 Positive_regulation of Fgfr2 1 0.45 0.07 0
86 INT270466 Ptch1 Regulation of Gene_expression of Shh 1 0.48 0.07 0
87 INT196022 Bmp7 Regulation of Bmp4 1 0.06 0.06 0
88 INT270460 Shh Positive_regulation of Gene_expression of Angpt1 1 0.04 0.08 0
89 INT270470 Shh Regulation of Gene_expression of VEGFA 1 0.39 0.15 0
90 INT311657 Binding of Cbl and Spry2 1 0.10 0.18 0
91 INT290907 Shh Positive_regulation of Ntn1 1 0.32 0.05 0
92 INT270469 Shh Positive_regulation of VEGFA 1 0.29 0.12 0
93 INT270468 Shh Positive_regulation of Gene_expression of VEGFA 1 0.44 0.08 0
94 INT264737 Hes1 Regulation of Shh 1 0.19 0.13 0
95 INT283711 Sox11 Regulation of 4930579C15Rik 1 0.28 0.74 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for lung morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported in lung morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT215353 Gene_expression of Tcf21 16 0.59 9.71 9.49
2 INT250832 Gene_expression of Fgf8 1 0.77 13.36 6.2
3 INT72834 Negative_regulation of Tcf21 10 0.58 5.8 4.84
4 INT75485 Gene_expression of Tgfbr2 10 0.57 10.98 3.76
5 INT22566 Positive_regulation of Tcf21 8 0.65 3.06 3.75
6 INT281367 Regulation of Gene_expression of Tcf21 1 0.09 1.39 2.89
7 INT281369 Negative_regulation of Gene_expression of Tcf21 1 0.08 1.4 2.44
8 INT2844 Positive_regulation of ID1 6 0.70 3.92 2.03
9 INT90004 Gene_expression of TCF21 4 0.65 2.48 2.02
10 INT135744 Positive_regulation of Id1 4 0.49 3.08 2.02
11 INT144973 Gene_expression of Shh 9 0.77 4.32 1.96
12 INT208561 Gene_expression of Shh 51 0.78 9.57 1.77
13 INT120088 Gene_expression of Bmp4 37 0.73 13.89 1.73
14 INT250841 Positive_regulation of Gene_expression of Fgf8 1 0.69 3.8 1.72
15 INT316162 Localization of TCF21 1 0.18 0.28 1.71
16 INT89871 Gene_expression of Gata4 11 0.69 1.05 1.53
17 INT222228 Positive_regulation of Gene_expression of Tcf21 4 0.38 0.84 1.39
18 INT110485 Binding of Tcf21 2 0.36 0.76 1.37
19 INT26658 Localization of ID1 1 0.32 0.18 1.33
20 INT250850 Negative_regulation of Gene_expression of Fgf8 1 0.42 2.79 1.33
21 INT316154 Positive_regulation of TCF21 4 0.17 1.22 1.23
22 INT253191 Positive_regulation of Gene_expression of Shh 2 0.66 2.57 1.14
23 INT250840 Negative_regulation of Fgf8 1 0.43 1.92 1.11
24 INT332771 Phosphorylation of Tcf21 1 0.09 0.21 1.07
25 INT332772 Positive_regulation of Phosphorylation of Tcf21 1 0.06 0.21 1.07
26 INT165530 Positive_regulation of Shh 4 0.69 1.21 1.05
27 INT277461 Positive_regulation of Gene_expression of Fgf8 1 0.24 0.47 1.05
28 INT109069 Transcription of Gata4 4 0.64 0.52 1.01
29 INT109070 Positive_regulation of Transcription of Gata4 1 0.03 0 1.01
30 INT102677 Negative_regulation of TCF21 2 0.41 0.22 0.89
31 INT142122 Regulation of Gene_expression of Bmp4 5 0.43 2.69 0.86
32 INT210247 Positive_regulation of Bmp4 6 0.65 4.36 0.8
33 INT9206 Negative_regulation of ID1 5 0.59 2.41 0.79
34 INT96422 Gene_expression of Bmp4 18 0.69 3.26 0.63
35 INT89867 Negative_regulation of Gene_expression of Gata4 3 0.38 0.17 0.61
36 INT281366 Regulation of Tcf21 1 0.09 0.23 0.59
37 INT296583 Gene_expression of Fgf10 3 0.59 2.64 0.57
38 INT89868 Negative_regulation of Gata4 1 0.38 0 0.57
39 INT296594 Regulation of Fgf10 1 0.15 1.53 0.56
40 INT316161 Negative_regulation of Gene_expression of TCF21 1 0.10 0.11 0.56
41 INT2845 Gene_expression of ID1 6 0.78 3.97 0.53
42 INT135749 Gene_expression of Id1 3 0.58 0.57 0.49
43 INT250845 Protein_catabolism of Fgf8 1 0.98 1.64 0.48
44 INT268007 Gene_expression of Fgf8 8 0.72 1.38 0.47
45 INT206484 Localization of Shh 2 0.75 1.14 0.46
46 INT142124 Binding of Bmp4 1 0.35 0.46 0.45
47 INT222229 Localization of Tcf21 1 0.57 0.45 0.45
48 INT232798 Positive_regulation of Gene_expression of Shh 7 0.70 1.49 0.44
49 INT277465 Regulation of Gene_expression of Fgf8 2 0.25 0.43 0.43
50 INT180688 Transcription of Bmp4 3 0.58 0.35 0.41
51 INT180702 Positive_regulation of Transcription of Bmp4 3 0.42 0.35 0.41
52 INT208559 Negative_regulation of Gene_expression of Shh 8 0.43 1.58 0.38
53 INT120899 Positive_regulation of Gene_expression of Tgfbr2 1 0.29 0.46 0.38
54 INT250826 Transcription of Fgf8 1 0.71 0.71 0.34
55 INT109058 Positive_regulation of Gene_expression of Gata4 2 0.29 0 0.33
56 INT283698 Gene_expression of Sox11 1 0.68 4.6 0.33
57 INT65266 Gene_expression of Plod3 1 0.17 0 0.3
58 INT159213 Gene_expression of BMP4 8 0.74 2.1 0.28
59 INT159212 Positive_regulation of Gene_expression of BMP4 2 0.66 0.91 0.28
60 INT232795 Positive_regulation of Shh 2 0.70 3.68 0.26
61 INT185009 Negative_regulation of BMP4 2 0.56 1.04 0.25
62 INT250836 Binding of Fgf8 3 0.35 0.66 0.24
63 INT142121 Positive_regulation of Gene_expression of Bmp4 3 0.47 7 0.21
64 INT250833 Localization of Fgf8 1 0.74 0.46 0.21
65 INT250842 Negative_regulation of Binding of Fgf8 1 0.43 0.33 0.21
66 INT65264 Positive_regulation of Gene_expression of Plod3 1 0.11 0 0.18
67 INT120085 Negative_regulation of Gene_expression of Bmp4 5 0.55 0.61 0.17
68 INT232799 Regulation of Gene_expression of Shh 3 0.27 1.04 0.16
69 INT118367 Positive_regulation of Gene_expression of ID1 2 0.69 0.25 0.16
70 INT253177 Negative_regulation of Gene_expression of Shh 2 0.55 0.63 0.16
71 INT118370 Regulation of ID1 2 0.45 0.58 0.16
72 INT250835 Positive_regulation of Fgf8 1 0.50 0.42 0.14
73 INT253190 Localization of Shh 2 0.77 1.06 0.13
74 INT253183 Negative_regulation of Shh 8 0.55 2.13 0.12
75 INT153250 Binding of ID1 2 0.25 0.65 0.1
76 INT287912 Localization of BMP4 1 0.18 1.13 0.1
77 INT196033 Negative_regulation of Gene_expression of Bmp4 3 0.21 0.45 0.09
78 INT270442 Transcription of Shh 1 0.53 0.25 0.09
79 INT213515 Binding of Shh 8 0.37 1.92 0.08
80 INT130400 Negative_regulation of Gene_expression of ID1 2 0.59 0.95 0.08
81 INT283695 Binding of Sox11 1 0.32 0.18 0.08
82 INT270453 Regulation of Shh 1 0.27 0.83 0.08
83 INT87714 Positive_regulation of Negative_regulation of ID1 2 0.29 0.87 0.07
84 INT280787 Gene_expression of Mapk8ip3 1 0.01 0.24 0.07
85 INT256862 Regulation of Shh 1 0.25 0 0.07
86 INT210243 Negative_regulation of Bmp4 1 0.55 0.55 0.07
87 INT270445 Positive_regulation of Localization of Shh 1 0.44 0.13 0.05
88 INT283696 Localization of Sox11 1 0.65 0.37 0.05
89 INT196030 Positive_regulation of Bmp4 6 0.62 2.55 0.04
90 INT208560 Negative_regulation of Shh 2 0.59 2.22 0.04
91 INT210238 Positive_regulation of Negative_regulation of Bmp4 1 0.47 0 0.04
92 INT253182 Positive_regulation of Positive_regulation of Bmp4 1 0.45 0.58 0.04
93 INT260760 Positive_regulation of Fgf10 2 0.53 0.43 0.03
94 INT248540 Positive_regulation of Gata4 2 0.23 0.95 0.03
95 INT303535 Positive_regulation of Gene_expression of Fgf10 1 0.53 0.34 0.03
96 INT253187 Negative_regulation of Transcription of Shh 1 0.41 0.55 0.03
97 INT253181 Transcription of Shh 1 0.68 0.54 0.03
98 INT196034 Positive_regulation of Gene_expression of Bmp4 4 0.45 0.63 0
99 INT260779 Negative_regulation of Bmp4 4 0.23 0.94 0
100 INT274404 Binding of Gata4 2 0.16 0.89 0
101 INT203465 Negative_regulation of Id1 2 0.06 0.68 0
102 INT196027 Binding of Bmp4 2 0.13 0.97 0
103 INT142119 Regulation of Bmp4 2 0.58 0.29 0
104 INT283699 Positive_regulation of Sox11 1 0.35 0.62 0
105 INT286395 Negative_regulation of Transcription of Mapk8ip3 1 0.55 0 0
106 INT339667 Localization of Bmp4 1 0.38 0.27 0
107 INT311645 Gene_expression of Spry2 1 0.70 1.81 0
108 INT325497 Negative_regulation of Gene_expression of Id1 1 0.19 0.48 0
109 INT310177 Binding of Tgfbr2 1 0.24 0 0
110 INT260764 Negative_regulation of Spry2 1 0.28 0.1 0
111 INT311634 Positive_regulation of Spry2 1 0.45 0.4 0
112 INT286400 Transcription of Mapk8ip3 1 0.68 0 0
113 INT290918 Negative_regulation of Positive_regulation of Shh 1 0.41 0.25 0
114 INT311633 Localization of Spry2 1 0.68 0.26 0
115 INT311628 Negative_regulation of Gene_expression of Spry2 1 0.39 0.43 0
116 INT286397 Negative_regulation of Mapk8ip3 1 0.41 0.06 0
117 INT250830 Regulation of Protein_catabolism of Fgf8 1 0.45 0.08 0
118 INT311651 Positive_regulation of Fgf8 1 0.46 0.26 0
119 INT310168 Phosphorylation of Tgfbr2 1 0.41 1.5 0
120 INT286391 Positive_regulation of Mapk8ip3 1 0.44 0.06 0
121 INT250846 Positive_regulation of Protein_catabolism of Fgf8 1 0.50 0.07 0
122 INT181811 Localization of Gata4 1 0.54 0.3 0
123 INT290929 Binding of Shh 1 0.31 0.1 0
124 INT311654 Regulation of Spry2 1 0.21 0.75 0
125 INT239992 Negative_regulation of Tgfbr2 1 0.06 0 0
126 INT184991 Negative_regulation of Regulation of ID1 1 0.31 0.27 0
127 INT310162 Gene_expression of Id1 1 0.10 1.45 0
128 INT351554 Negative_regulation of Gene_expression of BMP4 1 0.26 0 0
129 INT290927 Regulation of Positive_regulation of Shh 1 0.23 0 0
130 INT185016 Regulation of Gene_expression of ID1 1 0.44 0.26 0
131 INT270449 Negative_regulation of Positive_regulation of Shh 1 0.43 0.24 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox