GO:0060438

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Name trachea development
Categary Process
Go Slim No
Go Link GO:0060438
Unique Molecular Interactions 40
Total Molecular Interactions 59
Total Single Events 424
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for trachea development. They are ordered first by their pain relevance and then by number of times they were reported for trachea development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT287894 VEGFA Positive_regulation of Localization of BMP4 1 0.04 2.49 0.2
2 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19
3 INT287887 WNT1 Positive_regulation of Localization of BMP4 1 0.04 1.13 0.1
4 INT213418 Negative_regulation of FOXF1 Negative_regulation of Gene_expression of VCAM1 1 0.29 0.15 0.08
5 INT270464 Binding of Shh and Smo 1 0.07 1.3 0.08
6 INT290906 Shh Positive_regulation of Egfr 1 0.23 0 0.08
7 INT213419 Negative_regulation of FOXF1 Negative_regulation of Gene_expression of HGF 1 0.25 0.15 0.08
8 INT298349 HES3 Positive_regulation of Shh 1 0.12 0.14 0.07
9 INT290905 Gene_expression of Shh Positive_regulation of Gene_expression of Angpt1 1 0.14 0 0.06
10 INT210261 Bmp4 Regulation of Gene_expression of Tff3 1 0.64 0 0.05
11 INT213563 Binding of Ctnnd2 and Shh 1 0.27 0.09 0.04
12 INT270459 Binding of Shh and Gli1 1 0.02 0.65 0.04
13 INT306560 BMP4 Positive_regulation of MAPK1 1 0.09 0.09 0.03
14 INT352014 Shh Positive_regulation of Gene_expression of Pax1 1 0.29 0.07 0.03
15 INT311655 Shh Positive_regulation of Gene_expression of Fgf8 1 0.31 0.18 0.03
16 INT270462 Shh Positive_regulation of Ccnd1 1 0.10 0.6 0.03
17 INT213559 Binding of Egf and Shh 1 0.17 0.07 0.03
18 INT290910 Pkm2 Negative_regulation of Shh 1 0.07 0.06 0
19 INT314850 Shh Regulation of Atoh7 1 0.45 0.22 0
20 INT290908 Regulation of Shh Positive_regulation of Ntn1 1 0.12 0 0
21 INT290911 Gene_expression of Shh Positive_regulation of Pkm2 1 0.07 0 0
22 INT290904 Shh Positive_regulation of Prkcg 1 0.26 0.06 0
23 INT290900 Prkcg Regulation of Shh 1 0.23 0 0
24 INT290944 Shh Positive_regulation of VEGFA 1 0.04 0.05 0
25 INT270461 Shh Regulation of Gene_expression of Ptch1 1 0.48 0.07 0
26 INT196023 Bmp2 Negative_regulation of Gene_expression of Bmp4 1 0.09 0.07 0
27 INT196021 Bmp2 Positive_regulation of Gene_expression of Bmp4 1 0.09 0.08 0
28 INT270471 Shh Regulation of VEGFA 1 0.39 0.08 0
29 INT290898 Shh Positive_regulation of Nos2 1 0.46 0.05 0
30 INT270466 Ptch1 Regulation of Gene_expression of Shh 1 0.48 0.07 0
31 INT196022 Bmp7 Regulation of Bmp4 1 0.06 0.06 0
32 INT270460 Shh Positive_regulation of Gene_expression of Angpt1 1 0.04 0.08 0
33 INT270470 Shh Regulation of Gene_expression of VEGFA 1 0.39 0.15 0
34 INT290907 Shh Positive_regulation of Ntn1 1 0.32 0.05 0
35 INT270469 Shh Positive_regulation of VEGFA 1 0.29 0.12 0
36 INT270468 Shh Positive_regulation of Gene_expression of VEGFA 1 0.44 0.08 0
37 INT264737 Hes1 Regulation of Shh 1 0.19 0.13 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for trachea development. They are ordered first by their pain relevance and then by number of times they were reported in trachea development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT144973 Gene_expression of Shh 9 0.77 4.32 1.96
2 INT208561 Gene_expression of Shh 51 0.78 9.57 1.77
3 INT120088 Gene_expression of Bmp4 37 0.73 13.89 1.73
4 INT253191 Positive_regulation of Gene_expression of Shh 2 0.66 2.57 1.14
5 INT165530 Positive_regulation of Shh 4 0.69 1.21 1.05
6 INT142122 Regulation of Gene_expression of Bmp4 5 0.43 2.69 0.86
7 INT210247 Positive_regulation of Bmp4 6 0.65 4.36 0.8
8 INT96422 Gene_expression of Bmp4 18 0.69 3.26 0.63
9 INT206484 Localization of Shh 2 0.75 1.14 0.46
10 INT142124 Binding of Bmp4 1 0.35 0.46 0.45
11 INT232798 Positive_regulation of Gene_expression of Shh 7 0.70 1.49 0.44
12 INT180688 Transcription of Bmp4 3 0.58 0.35 0.41
13 INT180702 Positive_regulation of Transcription of Bmp4 3 0.42 0.35 0.41
14 INT208559 Negative_regulation of Gene_expression of Shh 8 0.43 1.58 0.38
15 INT159213 Gene_expression of BMP4 8 0.74 2.1 0.28
16 INT159212 Positive_regulation of Gene_expression of BMP4 2 0.66 0.91 0.28
17 INT232795 Positive_regulation of Shh 2 0.70 3.68 0.26
18 INT185009 Negative_regulation of BMP4 2 0.56 1.04 0.25
19 INT140639 Gene_expression of FOXF1 3 0.52 0.89 0.22
20 INT142121 Positive_regulation of Gene_expression of Bmp4 3 0.47 7 0.21
21 INT120085 Negative_regulation of Gene_expression of Bmp4 5 0.55 0.61 0.17
22 INT232799 Regulation of Gene_expression of Shh 3 0.27 1.04 0.16
23 INT253177 Negative_regulation of Gene_expression of Shh 2 0.55 0.63 0.16
24 INT249096 Regulation of FOXF1 1 0.19 0.28 0.14
25 INT253190 Localization of Shh 2 0.77 1.06 0.13
26 INT253183 Negative_regulation of Shh 8 0.55 2.13 0.12
27 INT213448 Localization of FOXF1 1 0.58 0.15 0.1
28 INT287912 Localization of BMP4 1 0.18 1.13 0.1
29 INT196033 Negative_regulation of Gene_expression of Bmp4 3 0.21 0.45 0.09
30 INT270442 Transcription of Shh 1 0.53 0.25 0.09
31 INT213515 Binding of Shh 8 0.37 1.92 0.08
32 INT270453 Regulation of Shh 1 0.27 0.83 0.08
33 INT213440 Negative_regulation of FOXF1 1 0.33 0.14 0.08
34 INT256862 Regulation of Shh 1 0.25 0 0.07
35 INT210243 Negative_regulation of Bmp4 1 0.55 0.55 0.07
36 INT270445 Positive_regulation of Localization of Shh 1 0.44 0.13 0.05
37 INT196030 Positive_regulation of Bmp4 6 0.62 2.55 0.04
38 INT208560 Negative_regulation of Shh 2 0.59 2.22 0.04
39 INT210238 Positive_regulation of Negative_regulation of Bmp4 1 0.47 0 0.04
40 INT253182 Positive_regulation of Positive_regulation of Bmp4 1 0.45 0.58 0.04
41 INT253187 Negative_regulation of Transcription of Shh 1 0.41 0.55 0.03
42 INT253181 Transcription of Shh 1 0.68 0.54 0.03
43 INT196034 Positive_regulation of Gene_expression of Bmp4 4 0.45 0.63 0
44 INT260779 Negative_regulation of Bmp4 4 0.23 0.94 0
45 INT196027 Binding of Bmp4 2 0.13 0.97 0
46 INT142119 Regulation of Bmp4 2 0.58 0.29 0
47 INT339667 Localization of Bmp4 1 0.38 0.27 0
48 INT290918 Negative_regulation of Positive_regulation of Shh 1 0.41 0.25 0
49 INT290929 Binding of Shh 1 0.31 0.1 0
50 INT351554 Negative_regulation of Gene_expression of BMP4 1 0.26 0 0
51 INT290927 Regulation of Positive_regulation of Shh 1 0.23 0 0
52 INT270449 Negative_regulation of Positive_regulation of Shh 1 0.43 0.24 0
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