GO:0060447

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Name bud outgrowth involved in lung branching
Categary Process
Go Slim No
Go Link GO:0060447
Unique Molecular Interactions 53
Total Molecular Interactions 71
Total Single Events 435
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for bud outgrowth involved in lung branching. They are ordered first by their pain relevance and then by number of times they were reported for bud outgrowth involved in lung branching. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT352462 Gse1 Positive_regulation of Gene_expression of Tnc 1 0.05 0.75 0.64
2 INT352459 Gse1 Regulation of Gene_expression of Tnc 1 0.05 0 0.6
3 INT161435 OPA1 Positive_regulation of Gene_expression of Tnc 1 0.02 0.21 0.32
4 INT352452 Calca Regulation of Gene_expression of Tnc 1 0.04 0 0.28
5 INT352448 Gse1 Regulation of Tnc 1 0.03 0 0.28
6 INT352458 Dusp1 Regulation of Gene_expression of Tnc 1 0.07 0 0.28
7 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19
8 INT352450 Tnc Regulation of Trib3 1 0.00 0.22 0.13
9 INT270464 Binding of Shh and Smo 1 0.07 1.3 0.08
10 INT290906 Shh Positive_regulation of Egfr 1 0.23 0 0.08
11 INT298349 HES3 Positive_regulation of Shh 1 0.12 0.14 0.07
12 INT303562 Binding of Fgf10 and Fgfr2 1 0.40 0.88 0.07
13 INT290905 Gene_expression of Shh Positive_regulation of Gene_expression of Angpt1 1 0.14 0 0.06
14 INT213563 Binding of Ctnnd2 and Shh 1 0.27 0.09 0.04
15 INT270459 Binding of Shh and Gli1 1 0.02 0.65 0.04
16 INT352014 Shh Positive_regulation of Gene_expression of Pax1 1 0.29 0.07 0.03
17 INT303563 Binding of Fgf10 and Dysf 1 0.00 0.44 0.03
18 INT311655 Shh Positive_regulation of Gene_expression of Fgf8 1 0.31 0.18 0.03
19 INT270462 Shh Positive_regulation of Ccnd1 1 0.10 0.6 0.03
20 INT213559 Binding of Egf and Shh 1 0.17 0.07 0.03
21 INT290910 Pkm2 Negative_regulation of Shh 1 0.07 0.06 0
22 INT205963 GLI1 Positive_regulation of Negative_regulation of SHH 1 0.22 0.58 0
23 INT314850 Shh Regulation of Atoh7 1 0.45 0.22 0
24 INT290908 Regulation of Shh Positive_regulation of Ntn1 1 0.12 0 0
25 INT290911 Gene_expression of Shh Positive_regulation of Pkm2 1 0.07 0 0
26 INT290904 Shh Positive_regulation of Prkcg 1 0.26 0.06 0
27 INT290900 Prkcg Regulation of Shh 1 0.23 0 0
28 INT205960 Binding of PTCH1 and SHH 1 0.21 0.71 0
29 INT290944 Shh Positive_regulation of VEGFA 1 0.04 0.05 0
30 INT270461 Shh Regulation of Gene_expression of Ptch1 1 0.48 0.07 0
31 INT205959 Binding of SHH and SMOX 1 0.12 0.72 0
32 INT270471 Shh Regulation of VEGFA 1 0.39 0.08 0
33 INT290898 Shh Positive_regulation of Nos2 1 0.46 0.05 0
34 INT202675 Fgf10 Positive_regulation of Fgfr2 1 0.45 0.07 0
35 INT270466 Ptch1 Regulation of Gene_expression of Shh 1 0.48 0.07 0
36 INT270460 Shh Positive_regulation of Gene_expression of Angpt1 1 0.04 0.08 0
37 INT270470 Shh Regulation of Gene_expression of VEGFA 1 0.39 0.15 0
38 INT290907 Shh Positive_regulation of Ntn1 1 0.32 0.05 0
39 INT205977 Binding of SHH and Ptch1 1 0.31 0.71 0
40 INT270469 Shh Positive_regulation of VEGFA 1 0.29 0.12 0
41 INT270468 Shh Positive_regulation of Gene_expression of VEGFA 1 0.44 0.08 0
42 INT264737 Hes1 Regulation of Shh 1 0.19 0.13 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for bud outgrowth involved in lung branching. They are ordered first by their pain relevance and then by number of times they were reported in bud outgrowth involved in lung branching. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT32054 Gene_expression of Tnc 14 0.59 9.36 12.22
2 INT4938 Localization of Tnc 5 0.65 1.73 5.64
3 INT79194 Positive_regulation of Tnc 5 0.41 2.25 4.69
4 INT32053 Positive_regulation of Gene_expression of Tnc 5 0.45 3.4 4.13
5 INT4939 Negative_regulation of Tnc 2 0.32 0.79 2.46
6 INT144973 Gene_expression of Shh 9 0.77 4.32 1.96
7 INT161432 Negative_regulation of Gene_expression of Tnc 2 0.38 1.44 1.93
8 INT208561 Gene_expression of Shh 51 0.78 9.57 1.77
9 INT253191 Positive_regulation of Gene_expression of Shh 2 0.66 2.57 1.14
10 INT165530 Positive_regulation of Shh 4 0.69 1.21 1.05
11 INT124873 Positive_regulation of Positive_regulation of Tnc 1 0.35 0.14 0.75
12 INT296583 Gene_expression of Fgf10 3 0.59 2.64 0.57
13 INT296594 Regulation of Fgf10 1 0.15 1.53 0.56
14 INT90353 Regulation of Gene_expression of Tnc 1 0.26 0.22 0.52
15 INT124872 Regulation of Localization of Tnc 1 0.31 0.1 0.52
16 INT206484 Localization of Shh 2 0.75 1.14 0.46
17 INT232798 Positive_regulation of Gene_expression of Shh 7 0.70 1.49 0.44
18 INT208559 Negative_regulation of Gene_expression of Shh 8 0.43 1.58 0.38
19 INT22786 Regulation of Tnc 1 0.23 0.18 0.37
20 INT232795 Positive_regulation of Shh 2 0.70 3.68 0.26
21 INT183062 Gene_expression of SHH 12 0.65 5.28 0.21
22 INT134477 Negative_regulation of SHH 2 0.37 1.13 0.2
23 INT232799 Regulation of Gene_expression of Shh 3 0.27 1.04 0.16
24 INT253177 Negative_regulation of Gene_expression of Shh 2 0.55 0.63 0.16
25 INT253190 Localization of Shh 2 0.77 1.06 0.13
26 INT253183 Negative_regulation of Shh 8 0.55 2.13 0.12
27 INT270442 Transcription of Shh 1 0.53 0.25 0.09
28 INT213515 Binding of Shh 8 0.37 1.92 0.08
29 INT270453 Regulation of Shh 1 0.27 0.83 0.08
30 INT205973 Binding of SHH 3 0.35 1.03 0.07
31 INT256862 Regulation of Shh 1 0.25 0 0.07
32 INT270445 Positive_regulation of Localization of Shh 1 0.44 0.13 0.05
33 INT181793 Positive_regulation of SHH 3 0.67 2.59 0.04
34 INT208560 Negative_regulation of Shh 2 0.59 2.22 0.04
35 INT260760 Positive_regulation of Fgf10 2 0.53 0.43 0.03
36 INT303535 Positive_regulation of Gene_expression of Fgf10 1 0.53 0.34 0.03
37 INT253187 Negative_regulation of Transcription of Shh 1 0.41 0.55 0.03
38 INT253181 Transcription of Shh 1 0.68 0.54 0.03
39 INT290918 Negative_regulation of Positive_regulation of Shh 1 0.41 0.25 0
40 INT230972 Positive_regulation of Gene_expression of SHH 1 0.18 0.07 0
41 INT290929 Binding of Shh 1 0.31 0.1 0
42 INT290927 Regulation of Positive_regulation of Shh 1 0.23 0 0
43 INT270449 Negative_regulation of Positive_regulation of Shh 1 0.43 0.24 0
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