GO:0060463

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Name lung lobe morphogenesis
Categary Process
Go Slim No
Go Link GO:0060463
Unique Molecular Interactions 394
Total Molecular Interactions 562
Total Single Events 4364
Pain Genes Associated 14

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for lung lobe morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported for lung lobe morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT142177 Calca Positive_regulation of Gene_expression of Igf1 8 0.78 3.57 5.71
2 INT145826 Calca Positive_regulation of Gene_expression of Igf1 3 0.75 3.05 1.66
3 INT131185 PTH Positive_regulation of Gene_expression of IGF1 3 0.44 3.31 1.31
4 INT131184 PTGER2 Positive_regulation of Gene_expression of IGF1 1 0.63 2.47 1.29
5 INT8416 LIF Regulation of TAC1 1 0.13 0.36 1.04
6 INT8415 LIF Regulation of VIP 1 0.13 0.36 1.04
7 INT106345 Igf1 Regulation of Localization of Acot1 1 0.06 0 1.02
8 INT56743 LIF Positive_regulation of Cck 1 0.08 0.18 1.02
9 INT75486 Binding of Tgfbr1 and Tgfbr2 1 0.10 1.94 1.02
10 INT12141 Igf1 Negative_regulation of Chat 1 0.32 0.63 1
11 INT56742 LIF Positive_regulation of Chat 1 0.02 0.2 0.98
12 INT140653 IGF1 Negative_regulation of Protein_catabolism of PARP1 1 0.32 0.63 0.98
13 INT140652 IGF1 Positive_regulation of Phosphorylation of MAPK1 1 0.26 0.63 0.98
14 INT188196 LIF Regulation of MAPK1 1 0.21 2.26 0.87
15 INT183176 Binding of FGFR2 and NUDT6 1 0.05 1.07 0.84
16 INT98479 Lif Regulation of Gene_expression of Grin1 1 0.04 0.35 0.82
17 INT149597 Lif Regulation of Regulation of Gal 1 0.30 0.69 0.73
18 INT149596 Lif Negative_regulation of Negative_regulation of Gal 1 0.10 0.5 0.7
19 INT28947 GH1 Positive_regulation of Gene_expression of IGF1 4 0.22 3.78 0.69
20 INT34772 GH1 Regulation of IGF1 2 0.32 0.95 0.69
21 INT220148 Binding of IGF1 and IGFBP3 12 0.36 5.56 0.66
22 INT45369 IGF1 Regulation of GH1 1 0.04 1.12 0.65
23 INT82267 Lif Regulation of Gene_expression of Gal 1 0.40 2.76 0.62
24 INT149595 Lif Negative_regulation of Negative_regulation of Trpv1 1 0.34 0.44 0.61
25 INT261828 Igf1 Regulation of Localization of Trpv2 1 0.02 1.04 0.58
26 INT156668 Gh Positive_regulation of Igf1 5 0.22 2.07 0.57
27 INT317639 Igf1 Regulation of Creb1 1 0.23 0.16 0.57
28 INT192291 OR5A1 Positive_regulation of Gene_expression of IGF1 1 0.02 0.93 0.57
29 INT156667 Gh Positive_regulation of Gene_expression of Igf1 6 0.28 0.88 0.56
30 INT150291 Grk1 Positive_regulation of Gene_expression of Igf1 1 0.16 0.98 0.55
31 INT106347 Igf1 Regulation of Chat 1 0.44 0 0.55
32 INT8440 Cntf Regulation of LIF 1 0.33 0.18 0.52
33 INT142882 IGF1 Positive_regulation of Gene_expression of TRPV1 1 0.06 0.57 0.52
34 INT98480 Lif Positive_regulation of Pnoc 1 0.18 0.2 0.49
35 INT108568 Calca Positive_regulation of Igf1 1 0.51 0.08 0.48
36 INT98484 Lif Regulation of Gene_expression of Gal 1 0.04 0.16 0.47
37 INT98482 Lif Positive_regulation of Gene_expression of Pnoc 1 0.16 0.17 0.46
38 INT98481 Lif Regulation of Regulation of Oprl1 1 0.04 0.16 0.45
39 INT264295 Binding of DMD and IGF1 1 0.07 1.38 0.44
40 INT188205 OSM Regulation of LIF 1 0.09 1.12 0.43
41 INT188207 LIF Regulation of IL6 1 0.17 1.12 0.43
42 INT221085 GHRH Positive_regulation of Gene_expression of IGF1 2 0.56 1.47 0.41
43 INT303655 Positive_regulation of Binding of IGF1 and SSTR1 1 0.16 2.19 0.41
44 INT75489 Binding of SGCG and Tgfbr2 1 0.23 0.83 0.41
45 INT75487 Binding of TGFB1 and Tgfbr2 1 0.31 0.83 0.41
46 INT303650 Binding of IGF1 and SSTR1 1 0.12 2.17 0.4
47 INT99304 Igf1 Positive_regulation of Gh1 1 0.44 0.39 0.39
48 INT91719 Binding of BDNF and LIF 1 0.09 1.65 0.38
49 INT182492 IL1B Regulation of Gene_expression of IGF1 1 0.01 0.83 0.38
50 INT78444 Binding of GH1 and IGF1 4 0.16 2.82 0.37
51 INT316545 Binding of IGF1 and SST 1 0.06 0.45 0.37
52 INT272951 Binding of TNF and Igf1 1 0.14 1.48 0.36
53 INT272953 Negative_regulation of Binding of TNF and Igf1 1 0.16 1.48 0.36
54 INT63278 Gpm6a Regulation of Igf1 1 0.01 0 0.36
55 INT272952 Igf1 Positive_regulation of Localization of TNF 1 0.19 1.53 0.35
56 INT277656 Igf1 Positive_regulation of Igfbp3 1 0.01 0.4 0.34
57 INT173947 Il6 Positive_regulation of Gene_expression of IGF1 1 0.05 1.02 0.31
58 INT65268 Igf1 Positive_regulation of Col7a1 1 0.48 0 0.3
59 INT51275 IGF1 Negative_regulation of INS 2 0.35 0.98 0.29
60 INT323653 Binding of Igf1 and Igfbp1 1 0.20 1.14 0.29
61 INT142885 Positive_regulation of IGF1 Positive_regulation of TRPV1 1 0.04 0.24 0.29
62 INT177476 Gnrhr Positive_regulation of Localization of Igf1 1 0.05 1.01 0.28
63 INT177478 Gnrhr Positive_regulation of Localization of IGF1 1 0.04 1.01 0.28
64 INT173949 Binding of IGF1 and Atp6v1e1 1 0.01 0.89 0.28
65 INT142884 IGF1 Positive_regulation of TRPV1 1 0.04 0.24 0.28
66 INT50303 Igf1 Regulation of Localization of Gnrhr 1 0.05 0.09 0.27
67 INT68872 Ghrh Regulation of IGF1 1 0.09 0.18 0.26
68 INT97188 Gh Positive_regulation of Localization of Igf1 1 0.02 0.54 0.25
69 INT7869 Gh Negative_regulation of IGF1 1 0.39 0.47 0.23
70 INT245590 Ghr Positive_regulation of Gene_expression of Igf1 1 0.34 0.61 0.23
71 INT265886 IGF1 Positive_regulation of AKT1 1 0.11 3.06 0.23
72 INT220383 Binding of Igf1 and Cotl1 1 0.03 0.37 0.22
73 INT173946 Igf1 Regulation of Gene_expression of IGF1 1 0.08 0.68 0.21
74 INT173944 IGF1 Regulation of Gene_expression of Igf1 1 0.08 0.68 0.21
75 INT173945 Hrt1 Positive_regulation of Positive_regulation of IGF1 1 0.01 0.32 0.21
76 INT286070 Igf1 Regulation of Regulation of Ins1 1 0.10 1.7 0.2
77 INT106825 Ednra Negative_regulation of Igf1 1 0.07 0.07 0.2
78 INT286071 Igf1 Regulation of Ins1 1 0.10 1.69 0.2
79 INT250537 Ptpn6 Negative_regulation of Igf1 1 0.08 0 0.2
80 INT82268 Lif Regulation of Gene_expression of Iapp 1 0.06 0.9 0.2
81 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19
82 INT220146 Binding of IGF1 and IGFBP1 2 0.10 1.57 0.19
83 INT173943 Binding of IGF1 and Il6 1 0.04 0.11 0.19
84 INT231033 Igf1 Positive_regulation of Sec22b 1 0.06 0 0.17
85 INT175991 Binding of VEGFA and Igf1 1 0.04 0.57 0.17
86 INT220387 Gh1 Regulation of Localization of Igf1 1 0.05 0.3 0.17
87 INT222426 Lif Positive_regulation of Localization of Pomc 1 0.02 0.75 0.17
88 INT265892 IGF1 Positive_regulation of PIK3CG 1 0.18 1.96 0.16
89 INT59952 Gh Positive_regulation of IGF1 1 0.46 0.84 0.16
90 INT269758 Negative_regulation of IGF1 Negative_regulation of Positive_regulation of IGFBP2 1 0.10 2.15 0.16
91 INT73076 IGF1 Positive_regulation of GH1 4 0.45 0.99 0.15
92 INT32211 POMC Positive_regulation of Gene_expression of Lif 1 0.01 0.61 0.15
93 INT334634 Binding of Igf1 and Igf1r 1 0.14 0.45 0.15
94 INT185515 Binding of Igf1 and Csf2 1 0.29 0.4 0.15
95 INT50302 Igf1 Regulation of Gh1 1 0.22 0 0.14
96 INT225778 Igf1 Negative_regulation of Positive_regulation of Ppi-rs 1 0.01 0.82 0.14
97 INT220385 Binding of Igf1 and Gnrhr 1 0.05 0.99 0.14
98 INT220386 Binding of Gh1 and Igf1 1 0.07 0.99 0.14
99 INT65272 Igf1 Positive_regulation of Binding of Col7a1 1 0.42 0 0.14
100 INT45371 IGF1 Regulation of Smc1b 1 0.08 0 0.14
101 INT303600 IGF1 Regulation of Gene_expression of GH1 1 0.39 0.83 0.14
102 INT65269 Igf1 Positive_regulation of Gene_expression of Lox 1 0.15 0 0.14
103 INT298715 Igf1 Positive_regulation of Gene_expression of PDGFA 1 0.00 0.22 0.14
104 INT45370 IGF1 Regulation of Gh1 1 0.13 0 0.14
105 INT68753 IGF1 Regulation of Gene_expression of Gh 2 0.02 0.68 0.13
106 INT253009 Igf1 Regulation of PTTG1 1 0.03 0.44 0.13
107 INT215034 Gh Regulation of Igf1 1 0.13 0.27 0.13
108 INT220147 IGFBP3 Positive_regulation of IGF1 1 0.10 0.53 0.13
109 INT65267 Igf1 Regulation of Gene_expression of Plod3 1 0.07 0 0.13
110 INT65271 Igf1 Positive_regulation of Gene_expression of Plod3 1 0.12 0 0.13
111 INT228453 Igf1 Positive_regulation of Prkca 2 0.12 1.17 0.12
112 INT188197 LIF Positive_regulation of STAT3 1 0.35 0.27 0.12
113 INT228456 Igf1 Positive_regulation of Trpv1 1 0.24 0.97 0.12
114 INT207551 IGF1 Positive_regulation of Gene_expression of GH1 2 0.22 1.18 0.11
115 INT308651 Binding of Igf1 and Ins1 1 0.02 0.22 0.11
116 INT175985 Igf1 Positive_regulation of Gene_expression of Serpina1c 1 0.14 0.55 0.11
117 INT323871 LEP Regulation of Gene_expression of IGF1 1 0.14 1.19 0.11
118 INT50301 Igf1 Positive_regulation of Regulation of Gh1 1 0.24 0 0.11
119 INT222507 Igf1 Positive_regulation of Localization of Edn3 1 0.05 0 0.11
120 INT175987 Igf1 Positive_regulation of Serpina1c 1 0.13 0.54 0.11
121 INT50300 Igf1 Positive_regulation of Gene_expression of Ghrh 1 0.26 0 0.11
122 INT323875 Binding of BMI1 and IGF1 1 0.01 1.2 0.11
123 INT51720 Negative_regulation of Ins1 Negative_regulation of Igf1 1 0.12 0.85 0.11
124 INT173948 Gh Positive_regulation of Gene_expression of IGF1 2 0.36 0.77 0.1
125 INT220149 Binding of IGF1 and IGFALS 2 0.39 0.44 0.1
126 INT267124 IGF1 Negative_regulation of Gene_expression of INS 2 0.14 0.18 0.1
127 INT294440 KLK4 Negative_regulation of LIF 1 0.00 0 0.1
128 INT277657 Igfbp1 Negative_regulation of Negative_regulation of Igf1 1 0.02 0.26 0.1
129 INT161741 Gh1 Positive_regulation of Gene_expression of Igf1 1 0.35 0.55 0.1
130 INT137368 Retn Positive_regulation of Gene_expression of IGF1 1 0.00 0.17 0.1
131 INT25501 Gnrhr Positive_regulation of Igf1 1 0.12 0.09 0.1
132 INT161742 Gnrhr Positive_regulation of Gene_expression of Igf1 1 0.25 0.55 0.1
133 INT190684 Binding of A2M and IGF1 1 0.16 1.54 0.1
134 INT316543 GH1 Regulation of Gene_expression of IGF1 1 0.03 1.32 0.09
135 INT265887 IGF1 Negative_regulation of BCL2 1 0.09 1.02 0.09
136 INT340555 Igf1 Positive_regulation of Mapk1 1 0.24 0.65 0.09
137 INT276141 Binding of Gh and Igf1 2 0.34 0.66 0.08
138 INT213418 Negative_regulation of FOXF1 Negative_regulation of Gene_expression of VCAM1 1 0.29 0.15 0.08
139 INT355019 Lif Positive_regulation of JAK1 1 0.00 0.69 0.08
140 INT49363 Gh Positive_regulation of Igf1 1 0.00 0.49 0.08
141 INT270464 Binding of Shh and Smo 1 0.07 1.3 0.08
142 INT192293 Binding of IGF1 and IL1B 1 0.15 0.08 0.08
143 INT175984 Igf1 Regulation of Localization of Serpina1c 1 0.14 0.54 0.08
144 INT9497 Gh Positive_regulation of Gene_expression of Igf1 1 0.08 0.31 0.08
145 INT290906 Shh Positive_regulation of Egfr 1 0.23 0 0.08
146 INT325058 Igf1 Positive_regulation of Ang 1 0.04 1.4 0.08
147 INT312219 Binding of IGF1 and IGFBP5 1 0.02 0.13 0.08
148 INT299539 Lif Positive_regulation of Phosphorylation of Stat3 1 0.08 0 0.08
149 INT355020 Lif Positive_regulation of SOAT1 1 0.02 0.7 0.08
150 INT213419 Negative_regulation of FOXF1 Negative_regulation of Gene_expression of HGF 1 0.25 0.15 0.08
151 INT355010 Lif Positive_regulation of Il6st 1 0.02 0.69 0.08
152 INT299548 Binding of TGFB1 and Lif 1 0.02 0 0.07
153 INT303561 Binding of Fgf7 and Fgfr2 1 0.42 0.88 0.07
154 INT323872 LEP Positive_regulation of Gene_expression of IGF1 1 0.35 0.77 0.07
155 INT265883 IGF1 Positive_regulation of Transcription of FOXO1 1 0.17 1.14 0.07
156 INT70762 IGF1 Regulation of Gh 1 0.00 0.17 0.07
157 INT265882 IGF1 Positive_regulation of Transcription of AKT1 1 0.08 1.13 0.07
158 INT12987 LIF Regulation of Localization of Prl 1 0.09 0 0.07
159 INT299535 Binding of Egf and Lif 1 0.07 0 0.07
160 INT298349 HES3 Positive_regulation of Shh 1 0.12 0.14 0.07
161 INT315987 Rhd Positive_regulation of Gene_expression of Igf1 1 0.10 0.47 0.07
162 INT303560 Binding of Fgfr2 and Fgf22 1 0.41 0.89 0.07
163 INT303562 Binding of Fgf10 and Fgfr2 1 0.40 0.88 0.07
164 INT142348 Igf1 Positive_regulation of Akt1 2 0.50 1.16 0.06
165 INT51273 IGF1 Positive_regulation of IGFBP2 1 0.37 0.13 0.06
166 INT142346 Igf1 Positive_regulation of Mapk3 1 0.75 0.33 0.06
167 INT290905 Gene_expression of Shh Positive_regulation of Gene_expression of Angpt1 1 0.14 0 0.06
168 INT295130 Igf1 Regulation of Grxcr1 1 0.02 0.64 0.06
169 INT343481 Epo Positive_regulation of Igf1 1 0.15 0.31 0.06
170 INT142345 Negative_regulation of Igf1 Positive_regulation of Akt1 1 0.42 0.33 0.06
171 INT295128 Igf1 Regulation of Transcription of Pou1f1 1 0.16 0.64 0.06
172 INT250538 Igf1 Positive_regulation of Gh 1 0.24 0.05 0.06
173 INT78445 Binding of GHRH and IGF1 1 0.20 0.72 0.06
174 INT51276 IGF1 Negative_regulation of GH1 1 0.10 0.13 0.06
175 INT51274 IGF1 Negative_regulation of IGF2 1 0.28 0.13 0.06
176 INT142347 Negative_regulation of Igf1 Positive_regulation of Mapk3 1 0.46 0.33 0.06
177 INT234619 IGF1 Regulation of IGF1R 1 0.11 0.39 0.05
178 INT336338 Glp2r Positive_regulation of Gene_expression of Igf1 1 0.14 0.24 0.05
179 INT218614 INS Positive_regulation of Binding of IGF1 1 0.39 0.79 0.05
180 INT339779 IGF1 Regulation of GHRH 1 0.08 0.38 0.05
181 INT335023 Fgf21 Positive_regulation of Gene_expression of Igf1 1 0.49 0.65 0.05
182 INT234624 Binding of IGF1 and IGF1R 1 0.09 0.39 0.05
183 INT112282 Ntf3 Regulation of Igf1 1 0.07 0.14 0.05
184 INT206619 Mtpn Positive_regulation of Igf1 1 0.04 0.17 0.05
185 INT234620 Regulation of Binding of IGF1 and IGF1R 1 0.07 0.39 0.05
186 INT250855 Binding of Fgfr2 and Fgf8 1 0.12 0.3 0.05
187 INT112281 Cntf Regulation of Igf1 1 0.22 0.14 0.05
188 INT198358 GH1 Regulation of Igf1 1 0.00 0.09 0.05
189 INT315986 Igf1 Positive_regulation of Pik3c3 1 0.00 0.48 0.05
190 INT184083 Positive_regulation of Gh Positive_regulation of Igf1 1 0.09 0.7 0.04
191 INT184115 Igf1 Positive_regulation of Gene_expression of Socs2 1 0.16 0.62 0.04
192 INT202233 IGFBP1 Regulation of IGF1 1 0.22 0.19 0.04
193 INT206620 Gh1 Positive_regulation of Igf1 1 0.25 0.17 0.04
194 INT268652 Binding of CLDN4 and LIF 1 0.35 0.44 0.04
195 INT213563 Binding of Ctnnd2 and Shh 1 0.27 0.09 0.04
196 INT261388 Nsdhl Regulation of Lif 1 0.08 0.67 0.04
197 INT270459 Binding of Shh and Gli1 1 0.02 0.65 0.04
198 INT202231 Binding of IGF1 and INS 2 0.28 1.38 0.03
199 INT261377 Nsdhl Positive_regulation of Lif 1 0.08 0.6 0.03
200 INT265891 IGF1 Regulation of AKT1 1 0.05 1.24 0.03

Single Events

The table below shows the top 100 pain related interactions that have been reported for lung lobe morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported in lung lobe morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07
2 INT14559 Gene_expression of Igf1 254 0.78 112 34.17
3 INT8915 Gene_expression of Igf1 199 0.78 78.58 32.51
4 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36
5 INT14556 Positive_regulation of Igf1 105 0.69 52.21 24.04
6 INT28951 Negative_regulation of IGF1 133 0.59 75.77 18.9
7 INT28950 Positive_regulation of Gene_expression of IGF1 99 0.69 46.9 16.47
8 INT65263 Positive_regulation of Gene_expression of Igf1 61 0.69 25.69 14.49
9 INT17539 Positive_regulation of Igf1 68 0.69 28.47 13.02
10 INT28952 Negative_regulation of Gene_expression of IGF1 75 0.58 41.11 12.32
11 INT11729 Regulation of IGF1 71 0.61 44.58 9.71
12 INT34777 Localization of IGF1 82 0.80 42.68 8.62
13 INT3803 Negative_regulation of Igf1 45 0.58 15.95 7.98
14 INT142344 Transcription of Igf1 22 0.69 7.55 6.77
15 INT2111 Gene_expression of LIF 34 0.77 16.82 6.76
16 INT14560 Regulation of Igf1 41 0.59 19.59 6.3
17 INT9494 Positive_regulation of Gene_expression of Igf1 34 0.67 17.77 6.26
18 INT9495 Negative_regulation of Gene_expression of Igf1 31 0.59 11.87 6.1
19 INT9321 Transcription of Igf1 25 0.69 10.2 6.08
20 INT8916 Regulation of Igf1 45 0.60 13.06 5.81
21 INT151032 Localization of Igf1 49 0.76 26.32 5.71
22 INT14557 Negative_regulation of Igf1 96 0.59 54.83 4.45
23 INT49360 Localization of Igf1 22 0.76 6.96 4.26
24 INT142174 Regulation of Gene_expression of Igf1 28 0.60 11.86 3.77
25 INT75485 Gene_expression of Tgfbr2 10 0.57 10.98 3.76
26 INT32208 Gene_expression of Lif 23 0.74 6.23 3.7
27 INT82265 Gene_expression of Lif 7 0.50 6.17 3.4
28 INT105537 Regulation of Gene_expression of Igf1 15 0.58 6.97 3.23
29 INT76240 Positive_regulation of Lif 6 0.69 6.04 3.13
30 INT131187 Regulation of Gene_expression of IGF1 18 0.62 11.18 3.05
31 INT16130 Binding of IGF1 67 0.48 27.43 2.95
32 INT139735 Positive_regulation of Transcription of Igf1 4 0.53 1.93 2.49
33 INT66544 Binding of Igf1 23 0.46 8.33 2.44
34 INT33895 Positive_regulation of LIF 9 0.67 2.47 2.34
35 INT144973 Gene_expression of Shh 9 0.77 4.32 1.96
36 INT156666 Positive_regulation of Localization of Igf1 11 0.62 6.94 1.95
37 INT142341 Positive_regulation of Transcription of Igf1 8 0.49 2.44 1.95
38 INT132971 Negative_regulation of Localization of IGF1 5 0.42 3.98 1.94
39 INT44027 Positive_regulation of Lif 7 0.40 2.76 1.9
40 INT208561 Gene_expression of Shh 51 0.78 9.57 1.77
41 INT66709 Transcription of IGF1 13 0.71 5.65 1.64
42 INT253751 Localization of Lif 3 0.73 3.94 1.58
43 INT50437 Regulation of LIF 6 0.44 2.12 1.53
44 INT49361 Regulation of Positive_regulation of Igf1 2 0.45 2.15 1.49
45 INT50436 Negative_regulation of Positive_regulation of LIF 1 0.37 0.33 1.42
46 INT135959 Negative_regulation of Gene_expression of Igf1 37 0.56 21.16 1.41
47 INT34933 Positive_regulation of Gene_expression of LIF 6 0.67 3.41 1.38
48 INT90491 Binding of Igf1 25 0.44 9.75 1.36
49 INT142616 Negative_regulation of Positive_regulation of Igf1 5 0.43 1.56 1.16
50 INT253191 Positive_regulation of Gene_expression of Shh 2 0.66 2.57 1.14
51 INT28949 Negative_regulation of Positive_regulation of IGF1 11 0.42 5.03 1.11
52 INT76890 Gene_expression of FGFR2 42 0.65 13.91 1.08
53 INT72129 Positive_regulation of Positive_regulation of IGF1 11 0.50 4.61 1.05
54 INT165530 Positive_regulation of Shh 4 0.69 1.21 1.05
55 INT169407 Phosphorylation of IGF1 4 0.63 0.83 1.01
56 INT149594 Positive_regulation of Gene_expression of Lif 2 0.47 0.89 1
57 INT102819 Regulation of Lif 8 0.53 2.05 0.87
58 INT98478 Negative_regulation of Lif 3 0.42 1.29 0.84
59 INT183182 Negative_regulation of FGFR2 2 0.29 1.25 0.84
60 INT82262 Regulation of Lif 3 0.31 1.67 0.83
61 INT354449 Positive_regulation of Localization of Lif 1 0.33 1.24 0.83
62 INT202241 Positive_regulation of Negative_regulation of IGF1 5 0.48 1.56 0.82
63 INT224958 Negative_regulation of Transcription of Igf1 5 0.56 1.37 0.81
64 INT68794 Negative_regulation of LIF 6 0.41 1.38 0.7
65 INT2109 Negative_regulation of Gene_expression of LIF 4 0.41 0.89 0.66
66 INT158136 Binding of FGFR2 9 0.26 4.5 0.63
67 INT124211 Protein_catabolism of IGF1 2 1.00 1.29 0.63
68 INT106343 Positive_regulation of Positive_regulation of Igf1 2 0.69 1.45 0.59
69 INT220365 Negative_regulation of Transcription of Igf1 3 0.45 1.28 0.56
70 INT125578 Positive_regulation of Localization of IGF1 6 0.60 7.59 0.53
71 INT49362 Positive_regulation of Localization of Igf1 4 0.65 2.26 0.53
72 INT185513 Phosphorylation of Igf1 3 0.67 0.46 0.5
73 INT146778 Negative_regulation of Fgfr2 1 0.32 0.66 0.48
74 INT216834 Localization of Lif 2 0.34 0.23 0.46
75 INT206484 Localization of Shh 2 0.75 1.14 0.46
76 INT299516 Phosphorylation of Lif 1 0.26 0.56 0.46
77 INT232798 Positive_regulation of Gene_expression of Shh 7 0.70 1.49 0.44
78 INT2110 Localization of LIF 5 0.73 1.59 0.44
79 INT140942 Regulation of Transcription of Igf1 3 0.32 1.37 0.43
80 INT32207 Regulation of Gene_expression of Lif 3 0.19 1.01 0.42
81 INT202626 Negative_regulation of Fgfr2 2 0.41 2.48 0.42
82 INT208559 Negative_regulation of Gene_expression of Shh 8 0.43 1.58 0.38
83 INT120899 Positive_regulation of Gene_expression of Tgfbr2 1 0.29 0.46 0.38
84 INT261774 Positive_regulation of Phosphorylation of Igf1 1 0.08 0.09 0.36
85 INT200198 Regulation of Localization of Igf1 6 0.58 4.51 0.34
86 INT49672 Regulation of Negative_regulation of IGF1 1 0.21 1.07 0.33
87 INT105968 Positive_regulation of Binding of Igf1 2 0.20 0.56 0.32
88 INT169405 Negative_regulation of Phosphorylation of IGF1 1 0.07 0.15 0.32
89 INT299519 Binding of Lif 2 0.21 0.67 0.29
90 INT232795 Positive_regulation of Shh 2 0.70 3.68 0.26
91 INT176080 Gene_expression of Fgfr2 4 0.68 2.34 0.24
92 INT188235 Phosphorylation of LIF 1 0.53 0.48 0.23
93 INT140639 Gene_expression of FOXF1 3 0.52 0.89 0.22
94 INT223739 Binding of Fgfr2 3 0.30 0.94 0.22
95 INT200200 Positive_regulation of Negative_regulation of Igf1 3 0.47 2.33 0.22
96 INT265899 Regulation of Binding of IGF1 2 0.22 0.94 0.22
97 INT183062 Gene_expression of SHH 12 0.65 5.28 0.21
98 INT134477 Negative_regulation of SHH 2 0.37 1.13 0.2
99 INT318610 Positive_regulation of Binding of Lif 1 0.28 0.67 0.19
100 INT173753 Positive_regulation of Negative_regulation of Igf1 1 0.34 0.47 0.19
101 INT172368 Negative_regulation of Binding of IGF1 3 0.42 1.57 0.18
102 INT188224 Regulation of Gene_expression of LIF 1 0.23 0.53 0.18
103 INT231055 Regulation of Localization of Igf1 1 0.15 0 0.17
104 INT188216 Positive_regulation of Regulation of LIF 1 0.39 1.13 0.17
105 INT198357 Negative_regulation of Localization of Igf1 1 0.03 0.51 0.17
106 INT232799 Regulation of Gene_expression of Shh 3 0.27 1.04 0.16
107 INT286068 Positive_regulation of Positive_regulation of Igf1 2 0.40 1.03 0.16
108 INT253177 Negative_regulation of Gene_expression of Shh 2 0.55 0.63 0.16
109 INT338147 Negative_regulation of Gene_expression of Lif 1 0.38 0.29 0.15
110 INT216451 Negative_regulation of Lif 1 0.36 0.77 0.15
111 INT185511 Regulation of Phosphorylation of Igf1 1 0.37 0 0.14
112 INT249096 Regulation of FOXF1 1 0.19 0.28 0.14
113 INT253190 Localization of Shh 2 0.77 1.06 0.13
114 INT175970 Negative_regulation of Phosphorylation of Igf1 2 0.39 2.1 0.13
115 INT285632 Regulation of Binding of Igf1 1 0.37 0.55 0.13
116 INT99718 Positive_regulation of Gene_expression of FGFR2 9 0.49 4.47 0.12
117 INT253183 Negative_regulation of Shh 8 0.55 2.13 0.12
118 INT212553 Negative_regulation of Transcription of IGF1 1 0.39 0.3 0.12
119 INT48615 Positive_regulation of Binding of IGF1 5 0.50 0.54 0.11
120 INT175968 Phosphorylation of Igf1 6 0.74 2.54 0.1
121 INT213448 Localization of FOXF1 1 0.58 0.15 0.1
122 INT270442 Transcription of Shh 1 0.53 0.25 0.09
123 INT213515 Binding of Shh 8 0.37 1.92 0.08
124 INT270453 Regulation of Shh 1 0.27 0.83 0.08
125 INT333440 Protein_catabolism of Lif 1 0.23 0.2 0.08
126 INT213440 Negative_regulation of FOXF1 1 0.33 0.14 0.08
127 INT205973 Binding of SHH 3 0.35 1.03 0.07
128 INT216454 Binding of Lif 2 0.27 0.85 0.07
129 INT318819 Positive_regulation of Transcription of IGF1 1 0.33 1.94 0.07
130 INT175972 Regulation of Phosphorylation of Igf1 1 0.41 0.95 0.07
131 INT256862 Regulation of Shh 1 0.25 0 0.07
132 INT299524 Positive_regulation of Localization of Lif 1 0.21 0 0.06
133 INT303546 Binding of Fgfr2 1 0.46 0.74 0.06
134 INT202238 Regulation of Transcription of IGF1 1 0.38 0 0.06
135 INT286067 Regulation of Regulation of Igf1 2 0.37 0.21 0.05
136 INT270445 Positive_regulation of Localization of Shh 1 0.44 0.13 0.05
137 INT181793 Positive_regulation of SHH 3 0.67 2.59 0.04
138 INT208560 Negative_regulation of Shh 2 0.59 2.22 0.04
139 INT333439 Positive_regulation of Gene_expression of Lif 1 0.18 0.18 0.04
140 INT303525 Localization of Fgfr2 1 0.72 0.28 0.03
141 INT266088 Positive_regulation of Localization of LIF 1 0.34 0.45 0.03
142 INT253187 Negative_regulation of Transcription of Shh 1 0.41 0.55 0.03
143 INT303547 Positive_regulation of Negative_regulation of Fgfr2 1 0.48 1.07 0.03
144 INT253181 Transcription of Shh 1 0.68 0.54 0.03
145 INT66346 Binding of LIF 7 0.47 0.9 0
146 INT207729 Regulation of FGFR2 4 0.22 2.35 0
147 INT238985 Positive_regulation of FGFR2 3 0.49 1.19 0
148 INT176243 Positive_regulation of Binding of Igf1 3 0.07 1.36 0
149 INT294924 Regulation of Localization of IGF1 3 0.39 1.07 0
150 INT185508 Protein_catabolism of Igf1 2 0.84 0 0
151 INT202239 Negative_regulation of Negative_regulation of IGF1 2 0.39 0.53 0
152 INT99716 Transcription of FGFR2 2 0.34 0.22 0
153 INT305351 Positive_regulation of Regulation of FGFR2 2 0.37 0.97 0
154 INT99715 Regulation of Gene_expression of FGFR2 2 0.22 0.19 0
155 INT142343 Negative_regulation of Regulation of Igf1 2 0.41 0.35 0
156 INT303555 Negative_regulation of Gene_expression of FGFR2 2 0.41 0.31 0
157 INT202623 Negative_regulation of Gene_expression of Fgfr2 1 0.32 0 0
158 INT319036 Gene_expression of Fgfr2 1 0.48 0.08 0
159 INT216450 Regulation of Transcription of Igf1 1 0.26 0 0
160 INT159329 Transcription of Lif 1 0.36 0.15 0
161 INT112084 Negative_regulation of Positive_regulation of Igf1 1 0.31 0.11 0
162 INT300189 Negative_regulation of Localization of Lif 1 0.41 0.47 0
163 INT268657 Regulation of Localization of LIF 1 0.38 0.07 0
164 INT310177 Binding of Tgfbr2 1 0.24 0 0
165 INT290918 Negative_regulation of Positive_regulation of Shh 1 0.41 0.25 0
166 INT295565 Positive_regulation of Phosphorylation of Igf1 1 0.19 0.17 0
167 INT274266 Regulation of Positive_regulation of IGF1 1 0.35 0.17 0
168 INT310168 Phosphorylation of Tgfbr2 1 0.41 1.5 0
169 INT264308 Negative_regulation of Regulation of IGF1 1 0.39 0.23 0
170 INT99717 Positive_regulation of Transcription of FGFR2 1 0.10 0.08 0
171 INT183117 Positive_regulation of Binding of FGFR2 1 0.09 0.81 0
172 INT269768 Negative_regulation of Negative_regulation of Igf1 1 0.08 0.96 0
173 INT230972 Positive_regulation of Gene_expression of SHH 1 0.18 0.07 0
174 INT290929 Binding of Shh 1 0.31 0.1 0
175 INT239992 Negative_regulation of Tgfbr2 1 0.06 0 0
176 INT112083 Negative_regulation of Negative_regulation of Igf1 1 0.31 0.22 0
177 INT290927 Regulation of Positive_regulation of Shh 1 0.23 0 0
178 INT303524 Positive_regulation of Fgfr2 1 0.66 0.22 0
179 INT246771 Negative_regulation of Phosphorylation of Igf1 1 0.09 0.37 0
180 INT270449 Negative_regulation of Positive_regulation of Shh 1 0.43 0.24 0
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