GO:0060484

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Name lung-associated mesenchyme development
Categary Process
Go Slim No
Go Link GO:0060484
Unique Molecular Interactions 86
Total Molecular Interactions 110
Total Single Events 778
Pain Genes Associated 12

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for lung-associated mesenchyme development. They are ordered first by their pain relevance and then by number of times they were reported for lung-associated mesenchyme development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT183176 Binding of FGFR2 and NUDT6 1 0.05 1.07 0.84
2 INT146780 Positive_regulation of Fgfr1 Positive_regulation of Mapk14 1 0.34 0.95 0.77
3 INT300609 Binding of Ctnnb1 and Wnt2 1 0.02 0.25 0.37
4 INT124378 Prodh2 Positive_regulation of Ctnnb1 1 0.00 0.59 0.35
5 INT9717 Binding of Egf and Fgfr1 1 0.15 0 0.22
6 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19
7 INT251115 Positive_regulation of Binding of AR and Ctnnb1 1 0.01 1.02 0.13
8 INT251114 Binding of AR and Ctnnb1 1 0.01 1 0.12
9 INT273018 Binding of FGF9 and PDE1A 1 0.18 0.3 0.11
10 INT273020 Binding of FGF9 and PDE11A 1 0.22 0.3 0.11
11 INT270464 Binding of Shh and Smo 1 0.07 1.3 0.08
12 INT290906 Shh Positive_regulation of Egfr 1 0.23 0 0.08
13 INT228501 Binding of AAVS1 and Fgfr1 1 0.01 0.57 0.07
14 INT303561 Binding of Fgf7 and Fgfr2 1 0.42 0.88 0.07
15 INT298349 HES3 Positive_regulation of Shh 1 0.12 0.14 0.07
16 INT303560 Binding of Fgfr2 and Fgf22 1 0.41 0.89 0.07
17 INT303562 Binding of Fgf10 and Fgfr2 1 0.40 0.88 0.07
18 INT290905 Gene_expression of Shh Positive_regulation of Gene_expression of Angpt1 1 0.14 0 0.06
19 INT250855 Binding of Fgfr2 and Fgf8 1 0.12 0.3 0.05
20 INT335017 Fgf23 Positive_regulation of Fgfr1 1 0.23 0.59 0.04
21 INT213563 Binding of Ctnnd2 and Shh 1 0.27 0.09 0.04
22 INT270459 Binding of Shh and Gli1 1 0.02 0.65 0.04
23 INT352014 Shh Positive_regulation of Gene_expression of Pax1 1 0.29 0.07 0.03
24 INT303558 Binding of Fgfr2 and Dysf 1 0.01 0.44 0.03
25 INT311655 Shh Positive_regulation of Gene_expression of Fgf8 1 0.31 0.18 0.03
26 INT270462 Shh Positive_regulation of Ccnd1 1 0.10 0.6 0.03
27 INT213559 Binding of Egf and Shh 1 0.17 0.07 0.03
28 INT205611 Gm6668 Negative_regulation of Fgfr1 1 0.01 1.59 0
29 INT290910 Pkm2 Negative_regulation of Shh 1 0.07 0.06 0
30 INT205963 GLI1 Positive_regulation of Negative_regulation of SHH 1 0.22 0.58 0
31 INT355603 Binding of CTNNA1 and Ctnnb1 1 0.00 1.07 0
32 INT314850 Shh Regulation of Atoh7 1 0.45 0.22 0
33 INT220818 Binding of Ctnnb1 and Myc 1 0.06 0.13 0
34 INT290908 Regulation of Shh Positive_regulation of Ntn1 1 0.12 0 0
35 INT286566 Binding of Ctnnb1 and Cdh6 1 0.00 1 0
36 INT290911 Gene_expression of Shh Positive_regulation of Pkm2 1 0.07 0 0
37 INT286562 Gene_expression of Pkd1 Positive_regulation of Ctnnb1 1 0.02 0.52 0
38 INT290904 Shh Positive_regulation of Prkcg 1 0.26 0.06 0
39 INT290900 Prkcg Regulation of Shh 1 0.23 0 0
40 INT136693 Gtf3a Positive_regulation of Ctnnb1 1 0.05 0 0
41 INT183091 Binding of FGF2 and FGFR2 1 0.03 0.79 0
42 INT320528 HOXA5 Regulation of Gene_expression of KRBA1 1 0.01 0.48 0
43 INT205960 Binding of PTCH1 and SHH 1 0.21 0.71 0
44 INT290944 Shh Positive_regulation of VEGFA 1 0.04 0.05 0
45 INT270461 Shh Regulation of Gene_expression of Ptch1 1 0.48 0.07 0
46 INT205959 Binding of SHH and SMOX 1 0.12 0.72 0
47 INT220821 Binding of MAX and Ctnnb1 1 0.09 0.13 0
48 INT270471 Shh Regulation of VEGFA 1 0.39 0.08 0
49 INT290898 Shh Positive_regulation of Nos2 1 0.46 0.05 0
50 INT286561 Binding of Ctnnb1 and Cdh2 1 0.00 1.06 0
51 INT342558 FGF9 Positive_regulation of MAPK3 1 0.03 1.21 0
52 INT202675 Fgf10 Positive_regulation of Fgfr2 1 0.45 0.07 0
53 INT342555 FGF9 Positive_regulation of MAPK1 1 0.07 1.22 0
54 INT286567 Prkd1 Regulation of Ctnnb1 1 0.01 0.39 0
55 INT270466 Ptch1 Regulation of Gene_expression of Shh 1 0.48 0.07 0
56 INT270460 Shh Positive_regulation of Gene_expression of Angpt1 1 0.04 0.08 0
57 INT270470 Shh Regulation of Gene_expression of VEGFA 1 0.39 0.15 0
58 INT290907 Shh Positive_regulation of Ntn1 1 0.32 0.05 0
59 INT205977 Binding of SHH and Ptch1 1 0.31 0.71 0
60 INT270469 Shh Positive_regulation of VEGFA 1 0.29 0.12 0
61 INT286572 Binding of Ctnnb1 and Pkd1 1 0.02 0.96 0
62 INT270468 Shh Positive_regulation of Gene_expression of VEGFA 1 0.44 0.08 0
63 INT264737 Hes1 Regulation of Shh 1 0.19 0.13 0
64 INT183089 Positive_regulation of Binding of FGF2 and FGFR2 1 0.04 0.4 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for lung-associated mesenchyme development. They are ordered first by their pain relevance and then by number of times they were reported in lung-associated mesenchyme development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT109391 Gene_expression of Fgfr1 7 0.56 1.78 3.67
2 INT119218 Positive_regulation of Fgfr1 4 0.58 1.11 3.05
3 INT101567 Gene_expression of Ctnnb1 7 0.64 10.11 2.89
4 INT81641 Gene_expression of Ctnnb1 23 0.72 14.93 1.97
5 INT144973 Gene_expression of Shh 9 0.77 4.32 1.96
6 INT208561 Gene_expression of Shh 51 0.78 9.57 1.77
7 INT123990 Positive_regulation of Ctnnb1 8 0.43 2.85 1.63
8 INT99391 Localization of Ctnnb1 7 0.80 5.84 1.61
9 INT99389 Negative_regulation of Ctnnb1 8 0.45 3.97 1.21
10 INT253191 Positive_regulation of Gene_expression of Shh 2 0.66 2.57 1.14
11 INT76890 Gene_expression of FGFR2 42 0.65 13.91 1.08
12 INT101570 Positive_regulation of Gene_expression of Ctnnb1 1 0.58 5.7 1.07
13 INT165530 Positive_regulation of Shh 4 0.69 1.21 1.05
14 INT101566 Negative_regulation of Gene_expression of Ctnnb1 1 0.35 2.28 0.88
15 INT183182 Negative_regulation of FGFR2 2 0.29 1.25 0.84
16 INT166537 Localization of Fgfr1 5 0.40 2.69 0.69
17 INT173508 Negative_regulation of Fgfr1 4 0.55 5.08 0.66
18 INT99390 Regulation of Ctnnb1 4 0.62 3.12 0.64
19 INT158136 Binding of FGFR2 9 0.26 4.5 0.63
20 INT146775 Phosphorylation of Fgfr1 1 0.53 0.8 0.62
21 INT150949 Gene_expression of Fgfr1 6 0.63 5.71 0.57
22 INT76960 Negative_regulation of Ctnnb1 5 0.57 3.46 0.53
23 INT146776 Transcription of Fgfr1 1 0.45 0.67 0.49
24 INT146777 Regulation of Transcription of Fgfr1 1 0.23 0.67 0.49
25 INT146778 Negative_regulation of Fgfr2 1 0.32 0.66 0.48
26 INT81645 Positive_regulation of Gene_expression of Ctnnb1 6 0.63 3.78 0.47
27 INT206484 Localization of Shh 2 0.75 1.14 0.46
28 INT232798 Positive_regulation of Gene_expression of Shh 7 0.70 1.49 0.44
29 INT188371 Regulation of Localization of Fgfr1 1 0.10 1.02 0.43
30 INT202626 Negative_regulation of Fgfr2 2 0.41 2.48 0.42
31 INT76958 Positive_regulation of Ctnnb1 14 0.64 5.48 0.41
32 INT95872 Localization of Ctnnb1 7 0.74 2.75 0.4
33 INT208559 Negative_regulation of Gene_expression of Shh 8 0.43 1.58 0.38
34 INT81644 Regulation of Ctnnb1 5 0.41 3.38 0.37
35 INT81643 Regulation of Gene_expression of Ctnnb1 3 0.57 1.5 0.37
36 INT150948 Positive_regulation of Gene_expression of Fgfr1 3 0.15 3.19 0.32
37 INT108324 Negative_regulation of Gene_expression of Ctnnb1 1 0.06 1.43 0.31
38 INT180696 Positive_regulation of Gene_expression of Fgfr1 1 0.32 0.08 0.28
39 INT232795 Positive_regulation of Shh 2 0.70 3.68 0.26
40 INT176080 Gene_expression of Fgfr2 4 0.68 2.34 0.24
41 INT285474 Negative_regulation of Gene_expression of Fgfr1 2 0.40 2.15 0.24
42 INT151719 Negative_regulation of Positive_regulation of Ctnnb1 1 0.23 1.9 0.24
43 INT223739 Binding of Fgfr2 3 0.30 0.94 0.22
44 INT183062 Gene_expression of SHH 12 0.65 5.28 0.21
45 INT254040 Regulation of FGF9 2 0.57 1.04 0.21
46 INT188373 Positive_regulation of Localization of Fgfr1 1 0.19 1.09 0.21
47 INT173515 Negative_regulation of Transcription of Fgfr1 1 0.06 0.92 0.21
48 INT303539 Binding of Fgfr1 3 0.45 0.96 0.2
49 INT134477 Negative_regulation of SHH 2 0.37 1.13 0.2
50 INT173503 Transcription of Fgfr1 1 0.08 0.92 0.2
51 INT139662 Gene_expression of FGF9 7 0.65 2.26 0.17
52 INT99392 Negative_regulation of Localization of Ctnnb1 2 0.59 1.43 0.17
53 INT151721 Negative_regulation of Localization of Ctnnb1 1 0.23 0.96 0.17
54 INT325506 Positive_regulation of Localization of Ctnnb1 1 0.05 0.28 0.17
55 INT232799 Regulation of Gene_expression of Shh 3 0.27 1.04 0.16
56 INT253177 Negative_regulation of Gene_expression of Shh 2 0.55 0.63 0.16
57 INT253190 Localization of Shh 2 0.77 1.06 0.13
58 INT130374 Transcription of Ctnnb1 1 0.19 0 0.13
59 INT99718 Positive_regulation of Gene_expression of FGFR2 9 0.49 4.47 0.12
60 INT253183 Negative_regulation of Shh 8 0.55 2.13 0.12
61 INT188374 Negative_regulation of Fgfr1 1 0.22 0.68 0.1
62 INT270442 Transcription of Shh 1 0.53 0.25 0.09
63 INT213515 Binding of Shh 8 0.37 1.92 0.08
64 INT250851 Binding of Fgfr1 1 0.10 0.19 0.08
65 INT270453 Regulation of Shh 1 0.27 0.83 0.08
66 INT205973 Binding of SHH 3 0.35 1.03 0.07
67 INT256862 Regulation of Shh 1 0.25 0 0.07
68 INT303546 Binding of Fgfr2 1 0.46 0.74 0.06
69 INT188372 Negative_regulation of Localization of Fgfr1 1 0.22 0.66 0.06
70 INT270445 Positive_regulation of Localization of Shh 1 0.44 0.13 0.05
71 INT181793 Positive_regulation of SHH 3 0.67 2.59 0.04
72 INT208560 Negative_regulation of Shh 2 0.59 2.22 0.04
73 INT303538 Positive_regulation of Fgfr1 3 0.65 0.92 0.03
74 INT303544 Positive_regulation of Negative_regulation of Fgfr1 1 0.47 1.07 0.03
75 INT303525 Localization of Fgfr2 1 0.72 0.28 0.03
76 INT253187 Negative_regulation of Transcription of Shh 1 0.41 0.55 0.03
77 INT303547 Positive_regulation of Negative_regulation of Fgfr2 1 0.48 1.07 0.03
78 INT253181 Transcription of Shh 1 0.68 0.54 0.03
79 INT303536 Localization of Fgfr1 1 0.70 0.28 0.03
80 INT207729 Regulation of FGFR2 4 0.22 2.35 0
81 INT238985 Positive_regulation of FGFR2 3 0.49 1.19 0
82 INT99716 Transcription of FGFR2 2 0.34 0.22 0
83 INT305351 Positive_regulation of Regulation of FGFR2 2 0.37 0.97 0
84 INT76959 Binding of Ctnnb1 2 0.34 0.69 0
85 INT99715 Regulation of Gene_expression of FGFR2 2 0.22 0.19 0
86 INT273600 Positive_regulation of FGF9 2 0.15 1.46 0
87 INT298673 Gene_expression of HOXA5 2 0.49 2.33 0
88 INT303555 Negative_regulation of Gene_expression of FGFR2 2 0.41 0.31 0
89 INT342561 Negative_regulation of FGF9 1 0.09 0.78 0
90 INT310246 Positive_regulation of Positive_regulation of Fgfr1 1 0.31 0 0
91 INT202623 Negative_regulation of Gene_expression of Fgfr2 1 0.32 0 0
92 INT319036 Gene_expression of Fgfr2 1 0.48 0.08 0
93 INT230651 Phosphorylation of Ctnnb1 1 0.10 0 0
94 INT230674 Positive_regulation of Phosphorylation of Ctnnb1 1 0.06 0 0
95 INT326137 Protein_catabolism of Ctnnb1 1 0.02 1.08 0
96 INT139665 Transcription of FGF9 1 0.04 0.11 0
97 INT320543 Positive_regulation of Gene_expression of HOXA5 1 0.44 0.57 0
98 INT355576 Negative_regulation of Negative_regulation of Ctnnb1 1 0.02 1.14 0
99 INT220769 Positive_regulation of Positive_regulation of Ctnnb1 1 0.10 0 0
100 INT342565 Localization of FGF9 1 0.16 0.79 0
101 INT290918 Negative_regulation of Positive_regulation of Shh 1 0.41 0.25 0
102 INT99717 Positive_regulation of Transcription of FGFR2 1 0.10 0.08 0
103 INT183117 Positive_regulation of Binding of FGFR2 1 0.09 0.81 0
104 INT180708 Regulation of Fgfr1 1 0.09 0 0
105 INT230972 Positive_regulation of Gene_expression of SHH 1 0.18 0.07 0
106 INT320550 Transcription of HOXA5 1 0.43 0 0
107 INT290929 Binding of Shh 1 0.31 0.1 0
108 INT342569 Positive_regulation of Gene_expression of FGF9 1 0.11 1.05 0
109 INT290927 Regulation of Positive_regulation of Shh 1 0.23 0 0
110 INT303524 Positive_regulation of Fgfr2 1 0.66 0.22 0
111 INT139659 Binding of FGF9 1 0.02 0.13 0
112 INT270449 Negative_regulation of Positive_regulation of Shh 1 0.43 0.24 0
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