GO:0060513

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Name prostatic bud formation
Categary Process
Go Slim No
Go Link GO:0060513
Unique Molecular Interactions 65
Total Molecular Interactions 82
Total Single Events 494
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for prostatic bud formation. They are ordered first by their pain relevance and then by number of times they were reported for prostatic bud formation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT104831 Binding of GLI2 and NFKB1 1 0.08 0 0.8
2 INT64067 Tp63 Negative_regulation of Localization of Gh1 1 0.08 0.07 0.76
3 INT64070 Tp63 Regulation of Ghrh 1 0.04 0.06 0.69
4 INT64068 Tp63 Regulation of Fdft1 1 0.00 0.06 0.69
5 INT278105 Negative_regulation of TP63 Negative_regulation of Binding of P2RX7 1 0.00 0 0.51
6 INT116938 Positive_regulation of GLI2 Positive_regulation of MAPK8 1 0.10 0.07 0.41
7 INT116936 Positive_regulation of GLI2 Positive_regulation of JUN 1 0.12 0.07 0.41
8 INT104834 Binding of GLI2 and IGKV2OR2-1 1 0.00 0 0.22
9 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19
10 INT303937 Positive_regulation of Binding of GLI2 and CCL5 1 0.01 0 0.18
11 INT303940 Regulation of Binding of GLI2 and CCL5 1 0.01 0 0.18
12 INT303938 Binding of GLI2 and CCL5 1 0.01 0 0.18
13 INT303939 TRAP Positive_regulation of Protein_catabolism of GLI2 1 0.01 0 0.16
14 INT303941 CCL2 Positive_regulation of Protein_catabolism of GLI2 1 0.01 0 0.16
15 INT104837 IGKV2OR2-1 Negative_regulation of GLI2 1 0.00 0 0.15
16 INT270464 Binding of Shh and Smo 1 0.07 1.3 0.08
17 INT290906 Shh Positive_regulation of Egfr 1 0.23 0 0.08
18 INT298349 HES3 Positive_regulation of Shh 1 0.12 0.14 0.07
19 INT290905 Gene_expression of Shh Positive_regulation of Gene_expression of Angpt1 1 0.14 0 0.06
20 INT343538 TGFB1 Positive_regulation of Gene_expression of GLI2 1 0.08 0.2 0.05
21 INT213563 Binding of Ctnnd2 and Shh 1 0.27 0.09 0.04
22 INT270459 Binding of Shh and Gli1 1 0.02 0.65 0.04
23 INT352014 Shh Positive_regulation of Gene_expression of Pax1 1 0.29 0.07 0.03
24 INT343545 Binding of GLI2 and ROCK1 1 0.07 0.65 0.03
25 INT311655 Shh Positive_regulation of Gene_expression of Fgf8 1 0.31 0.18 0.03
26 INT270462 Shh Positive_regulation of Ccnd1 1 0.10 0.6 0.03
27 INT213559 Binding of Egf and Shh 1 0.17 0.07 0.03
28 INT343544 Negative_regulation of GLI2 Negative_regulation of Gene_expression of PTHLH 1 0.24 0.53 0.03
29 INT348532 TP63 Positive_regulation of CASP3 1 0.04 0.55 0
30 INT292882 Binding of S100A12 and TP63 1 0.06 0.51 0
31 INT290910 Pkm2 Negative_regulation of Shh 1 0.07 0.06 0
32 INT314850 Shh Regulation of Atoh7 1 0.45 0.22 0
33 INT290908 Regulation of Shh Positive_regulation of Ntn1 1 0.12 0 0
34 INT290911 Gene_expression of Shh Positive_regulation of Pkm2 1 0.07 0 0
35 INT290904 Shh Positive_regulation of Prkcg 1 0.26 0.06 0
36 INT290900 Prkcg Regulation of Shh 1 0.23 0 0
37 INT348540 TP63 Positive_regulation of CASP8 1 0.03 0.55 0
38 INT235647 TP63 Regulation of EPHA2 1 0.15 0.97 0
39 INT290944 Shh Positive_regulation of VEGFA 1 0.04 0.05 0
40 INT270461 Shh Regulation of Gene_expression of Ptch1 1 0.48 0.07 0
41 INT207374 Gene_expression of GLI2 Negative_regulation of Gene_expression of Chol1 1 0.04 0 0
42 INT343548 GLI2 Positive_regulation of Gene_expression of PTHLH 1 0.28 0.94 0
43 INT235646 TP63 Regulation of EFNA1 1 0.09 0.97 0
44 INT280546 Binding of KIT and TP63 1 0.01 1.19 0
45 INT270471 Shh Regulation of VEGFA 1 0.39 0.08 0
46 INT139032 Binding of Oprm1 and Tp63 1 0.25 0.05 0
47 INT290898 Shh Positive_regulation of Nos2 1 0.46 0.05 0
48 INT343549 GLI2 Positive_regulation of GYPA 1 0.05 0.95 0
49 INT270466 Ptch1 Regulation of Gene_expression of Shh 1 0.48 0.07 0
50 INT348536 Positive_regulation of TP63 Positive_regulation of Gene_expression of CASP9 1 0.02 0.55 0
51 INT207336 Gene_expression of GLI2 Negative_regulation of Gene_expression of CYP27A1 1 0.00 0 0
52 INT270460 Shh Positive_regulation of Gene_expression of Angpt1 1 0.04 0.08 0
53 INT139033 Positive_regulation of Binding of Oprm1 and Tp63 1 0.32 0.05 0
54 INT270470 Shh Regulation of Gene_expression of VEGFA 1 0.39 0.15 0
55 INT290907 Shh Positive_regulation of Ntn1 1 0.32 0.05 0
56 INT270469 Shh Positive_regulation of VEGFA 1 0.29 0.12 0
57 INT320887 Binding of TP63 and olt 1 0.01 2.15 0
58 INT343539 GLI2 Regulation of PTHLH 1 0.15 0.25 0
59 INT270468 Shh Positive_regulation of Gene_expression of VEGFA 1 0.44 0.08 0
60 INT264737 Hes1 Regulation of Shh 1 0.19 0.13 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for prostatic bud formation. They are ordered first by their pain relevance and then by number of times they were reported in prostatic bud formation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT111476 Gene_expression of TP63 88 0.76 61.08 11.64
2 INT64170 Gene_expression of GLI2 31 0.46 14.96 3.99
3 INT12844 Binding of TP63 15 0.47 10.57 3.38
4 INT144973 Gene_expression of Shh 9 0.77 4.32 1.96
5 INT208561 Gene_expression of Shh 51 0.78 9.57 1.77
6 INT90926 Positive_regulation of GLI2 12 0.45 4.99 1.74
7 INT113985 Positive_regulation of TP63 9 0.50 8.79 1.62
8 INT193823 Positive_regulation of Gene_expression of TP63 7 0.18 7.74 1.57
9 INT104839 Negative_regulation of GLI2 8 0.35 2.7 1.24
10 INT253191 Positive_regulation of Gene_expression of Shh 2 0.66 2.57 1.14
11 INT278117 Negative_regulation of TP63 5 0.32 3.38 1.13
12 INT165530 Positive_regulation of Shh 4 0.69 1.21 1.05
13 INT119674 Localization of GLI2 6 0.52 2.84 0.99
14 INT182322 Negative_regulation of Gene_expression of GLI2 6 0.11 2.37 0.98
15 INT64173 Regulation of Gene_expression of GLI2 4 0.37 2.89 0.88
16 INT289474 Regulation of GLI2 2 0.06 1.08 0.87
17 INT44293 Regulation of TP63 6 0.24 2.88 0.76
18 INT104840 Binding of GLI2 6 0.08 1.89 0.72
19 INT306741 Positive_regulation of Positive_regulation of TP63 2 0.05 1.16 0.49
20 INT278121 Negative_regulation of Negative_regulation of TP63 1 0.03 0 0.48
21 INT206484 Localization of Shh 2 0.75 1.14 0.46
22 INT232798 Positive_regulation of Gene_expression of Shh 7 0.70 1.49 0.44
23 INT208559 Negative_regulation of Gene_expression of Shh 8 0.43 1.58 0.38
24 INT119675 Positive_regulation of Localization of GLI2 1 0.32 0.43 0.3
25 INT234407 Positive_regulation of Binding of GLI2 2 0.05 1.33 0.28
26 INT232795 Positive_regulation of Shh 2 0.70 3.68 0.26
27 INT303943 Protein_catabolism of GLI2 2 0.11 0 0.22
28 INT232799 Regulation of Gene_expression of Shh 3 0.27 1.04 0.16
29 INT182321 Positive_regulation of Gene_expression of GLI2 2 0.28 1.32 0.16
30 INT253177 Negative_regulation of Gene_expression of Shh 2 0.55 0.63 0.16
31 INT139201 Localization of TP63 4 0.32 2.56 0.15
32 INT145147 Negative_regulation of Gene_expression of TP63 4 0.42 2.91 0.15
33 INT256864 Gene_expression of Tp63 1 0.14 0.47 0.14
34 INT253190 Localization of Shh 2 0.77 1.06 0.13
35 INT253183 Negative_regulation of Shh 8 0.55 2.13 0.12
36 INT270442 Transcription of Shh 1 0.53 0.25 0.09
37 INT213515 Binding of Shh 8 0.37 1.92 0.08
38 INT270453 Regulation of Shh 1 0.27 0.83 0.08
39 INT256854 Regulation of Tp63 1 0.06 0.06 0.08
40 INT136890 Protein_catabolism of TP63 2 0.56 1.17 0.07
41 INT256862 Regulation of Shh 1 0.25 0 0.07
42 INT270445 Positive_regulation of Localization of Shh 1 0.44 0.13 0.05
43 INT208560 Negative_regulation of Shh 2 0.59 2.22 0.04
44 INT253187 Negative_regulation of Transcription of Shh 1 0.41 0.55 0.03
45 INT253181 Transcription of Shh 1 0.68 0.54 0.03
46 INT209451 Regulation of Gene_expression of TP63 3 0.16 4.32 0
47 INT207371 Positive_regulation of Transcription of GLI2 1 0.03 0.08 0
48 INT290918 Negative_regulation of Positive_regulation of Shh 1 0.41 0.25 0
49 INT280555 Regulation of Binding of TP63 1 0.12 0.93 0
50 INT307407 Regulation of Localization of GLI2 1 0.01 0.67 0
51 INT207369 Transcription of GLI2 1 0.05 0.08 0
52 INT290929 Binding of Shh 1 0.31 0.1 0
53 INT290927 Regulation of Positive_regulation of Shh 1 0.23 0 0
54 INT201567 Positive_regulation of Protein_catabolism of TP63 1 0.23 1.17 0
55 INT270449 Negative_regulation of Positive_regulation of Shh 1 0.43 0.24 0
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