GO:0060523

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Name prostate epithelial cord elongation
Categary Process
Go Slim No
Go Link GO:0060523
Unique Molecular Interactions 297
Total Molecular Interactions 376
Total Single Events 3971
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for prostate epithelial cord elongation. They are ordered first by their pain relevance and then by number of times they were reported for prostate epithelial cord elongation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT108810 Esr1 Positive_regulation of Binding of Oprm1 1 0.51 1.79 3.22
2 INT158079 Binding of Esr1 and Gper 1 0.31 0.97 1.35
3 INT222182 Binding of ESR1 and HLA-DRB2 1 0.00 3.1 1.35
4 INT150890 Binding of Esr1 and Esr2 2 0.52 2.06 1.31
5 INT278292 Binding of CRP and ESR1 6 0.09 10.92 0.96
6 INT183176 Binding of FGFR2 and NUDT6 1 0.05 1.07 0.84
7 INT108812 Esr1 Positive_regulation of Positive_regulation of Oprm1 1 0.42 0.38 0.78
8 INT38057 Binding of Crp and Esr1 2 0.04 1.21 0.65
9 INT309158 Binding of Esr1 and Dlat 1 0.04 1.39 0.61
10 INT341594 Binding of ESR1 and HLA-B 1 0.01 0.72 0.57
11 INT150833 Esr1 Positive_regulation of Localization of Prkce 1 0.08 0.29 0.51
12 INT291556 Binding of ESR1 and Sec22b 2 0.00 0.86 0.5
13 INT154014 Binding of Esr1 and Gabrg1 1 0.07 0.07 0.5
14 INT147179 Esr1 Regulation of Gene_expression of Penk 1 0.01 0.68 0.46
15 INT323840 Binding of Esr1 and Il1 1 0.04 0.9 0.42
16 INT261370 Nsdhl Regulation of Esr1 1 0.01 0.75 0.41
17 INT117361 Binding of Esr1 and sea 1 0.02 1.38 0.38
18 INT199974 ESR1 Negative_regulation of Gene_expression of ITGB3BP 1 0.05 0.47 0.38
19 INT197591 Esr1 Regulation of Pgr 1 0.04 0 0.38
20 INT117359 Binding of Esr1 and Wbc1 1 0.00 1.38 0.37
21 INT291555 Binding of ESR1 and Dlat 1 0.01 0.6 0.35
22 INT291554 Binding of ESR1 and St8sia2 1 0.01 0.49 0.33
23 INT128756 Binding of Esr1 and Foxc1 1 0.01 0.43 0.32
24 INT309156 Esr1 Regulation of Gene_expression of Dlat 1 0.05 1.06 0.3
25 INT222301 Binding of ERBB2 and ESR1 5 0.36 5.07 0.29
26 INT158734 Esr1 Regulation of Esrrb 1 0.00 0.28 0.29
27 INT158733 Esr1 Regulation of Plxna3 1 0.03 0.27 0.29
28 INT185092 CRP Positive_regulation of ESR1 1 0.06 2.83 0.28
29 INT199978 ESR1 Regulation of ITGB3BP 1 0.03 0.39 0.28
30 INT71904 Binding of ESR1 and PGR 6 0.34 3.79 0.27
31 INT323152 Binding of DBT and ESR1 2 0.02 1.29 0.27
32 INT346195 AMELX Negative_regulation of ESR1 1 0.02 0.36 0.26
33 INT263587 Pdia3 Negative_regulation of Binding of Esr1 1 0.07 1.86 0.26
34 INT186783 Binding of ESR1 and NRIP1 1 0.31 0.79 0.25
35 INT199970 CYP19A1 Positive_regulation of Gene_expression of ESR1 1 0.06 0.72 0.25
36 INT182346 Binding of Cd3e and Esr1 1 0.06 1.26 0.25
37 INT182349 Binding of Ms4a1 and Esr1 1 0.04 1.26 0.25
38 INT199971 IL6 Positive_regulation of ESR1 1 0.08 0.84 0.24
39 INT309160 Binding of Esr1 and Edc4 1 0.03 0.34 0.24
40 INT63203 INS Positive_regulation of ESR1 1 0.09 0.3 0.23
41 INT63198 POMC Positive_regulation of ESR1 1 0.14 0.3 0.23
42 INT270135 Binding of ESR1 and RALA 1 0.11 0.37 0.22
43 INT63192 PTH Positive_regulation of ESR1 1 0.20 0.29 0.22
44 INT308645 Binding of Esr1 and Itpr3 1 0.00 0 0.2
45 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19
46 INT351086 Negative_regulation of ERBB2 Positive_regulation of Gene_expression of ESR1 1 0.10 0.75 0.19
47 INT351089 FOXO3 Positive_regulation of Gene_expression of ESR1 1 0.04 0.74 0.19
48 INT192219 CASP3 Regulation of ESR1 1 0.03 1.19 0.19
49 INT197618 Binding of Esr1 and Ppt1 1 0.01 0 0.18
50 INT173932 Binding of Esr1 and Il6 1 0.03 0.11 0.18
51 INT19042 ESR1 Positive_regulation of GGT5 1 0.03 0.6 0.17
52 INT19045 ESR1 Positive_regulation of Salpa1 1 0.02 0.6 0.17
53 INT309154 Esr1 Positive_regulation of Gsdmc 1 0.01 0.44 0.15
54 INT309155 Negative_regulation of Esr1 Positive_regulation of Gsdmc 1 0.01 0.45 0.15
55 INT181752 Binding of CPOX and ESR1 1 0.02 0.89 0.14
56 INT291644 Binding of DST and ESR1 1 0.05 0.84 0.14
57 INT297312 Esr1 Positive_regulation of Scap 1 0.00 1.58 0.13
58 INT267973 Binding of CHKB and ESR1 1 0.02 1.67 0.13
59 INT86429 Binding of Hspb1 and Esr1 1 0.19 0.26 0.13
60 INT236588 Binding of Esr1 and Ins1 1 0.05 0.73 0.12
61 INT341827 Binding of ESR1 and TNC 1 0.14 0.63 0.11
62 INT341775 DBT Regulation of Binding of ESR1 1 0.02 0.1 0.11
63 INT252779 Binding of ESR1 and RAF1 1 0.01 2.03 0.11
64 INT220114 Tnfrsf1a Positive_regulation of Esr1 1 0.14 1.14 0.1
65 INT237819 Binding of Esr1 and soc 1 0.04 0 0.1
66 INT279407 Binding of ESR1 and IGKV2-19 1 0.02 0.4 0.1
67 INT125000 Binding of Esr1 and Tas2r108 1 0.04 0.33 0.1
68 INT237812 Esr1 Positive_regulation of Positive_regulation of soc 1 0.05 0.6 0.1
69 INT201747 Itpr3 Positive_regulation of Localization of Esr1 2 0.03 1.19 0.09
70 INT308662 Binding of Esr1 and Fdft1 1 0.00 0.05 0.09
71 INT232559 Map3k1 Positive_regulation of Esr1 1 0.19 0.26 0.09
72 INT261396 Nsdhl Positive_regulation of Transcription of Esr1 1 0.02 2.1 0.09
73 INT341776 ESR1 Positive_regulation of Gene_expression of SLC6A3 1 0.06 0.08 0.09
74 INT232557 Erbb2 Positive_regulation of Esr1 1 0.23 0.26 0.09
75 INT52836 ESR1 Positive_regulation of HSD17B7 1 0.43 0.41 0.09
76 INT270464 Binding of Shh and Smo 1 0.07 1.3 0.08
77 INT192863 Binding of Ddit3 and Esr1 1 0.09 0.67 0.08
78 INT192860 Binding of Calr and Esr1 1 0.06 0.67 0.08
79 INT192865 Binding of Esr1 and Pdia3 1 0.07 0.67 0.08
80 INT192862 Binding of Esr1 and Hspa5 1 0.08 0.68 0.08
81 INT309159 Binding of Cav1 and Positive_regulation of Localization of Esr1 1 0.04 0 0.08
82 INT290906 Shh Positive_regulation of Egfr 1 0.23 0 0.08
83 INT199973 ESR1 Negative_regulation of EEF1B2P2 1 0.01 0.46 0.08
84 INT38188 PGR Positive_regulation of Gene_expression of ESR1 1 0.42 0.22 0.07
85 INT303561 Binding of Fgf7 and Fgfr2 1 0.42 0.88 0.07
86 INT237811 Binding of Esr1 and Stim1 1 0.09 0 0.07
87 INT339108 Binding of ESR1 and JUP 1 0.38 0.62 0.07
88 INT224293 AR Positive_regulation of Protein_catabolism of ESR1 1 0.24 0.4 0.07
89 INT237809 Esr1 Positive_regulation of Localization of Car2 1 0.09 0.66 0.07
90 INT298349 HES3 Positive_regulation of Shh 1 0.12 0.14 0.07
91 INT303560 Binding of Fgfr2 and Fgf22 1 0.41 0.89 0.07
92 INT206855 Binding of ESR1 and PPARA 1 0.03 1.21 0.07
93 INT303562 Binding of Fgf10 and Fgfr2 1 0.40 0.88 0.07
94 INT272388 Esr1 Regulation of Transcription of Trpv6 1 0.03 0.13 0.06
95 INT290905 Gene_expression of Shh Positive_regulation of Gene_expression of Angpt1 1 0.14 0 0.06
96 INT197594 Esr1 Regulation of Esr2 1 0.04 0 0.06
97 INT187845 Binding of ESR1 and Esr2 1 0.01 0.17 0.06
98 INT197592 Esr2 Regulation of Esr1 1 0.04 0 0.06
99 INT142744 Esr1 Regulation of Transcription of Trpv6 1 0.42 0 0.06
100 INT206846 ESR1 Regulation of Gene_expression of PLP1 1 0.06 1.02 0.05
101 INT242974 Mapk8 Negative_regulation of Positive_regulation of Esr1 1 0.01 1.39 0.05
102 INT236591 Binding of Esr1 and Positive_regulation of Tmed4 1 0.04 0.52 0.05
103 INT240726 Binding of Esr1 and Ca2 1 0.02 0.57 0.05
104 INT250855 Binding of Fgfr2 and Fgf8 1 0.12 0.3 0.05
105 INT316248 ESR1 Regulation of Gene_expression of TRPM8 1 0.34 0.17 0.05
106 INT244461 CS Positive_regulation of ESR1 1 0.06 1.15 0.05
107 INT225493 Binding of Esr1 and Pprc1 2 0.01 0.17 0.04
108 INT335702 Esr1 Regulation of Calr 1 0.03 0 0.04
109 INT206848 PLP1 Regulation of Gene_expression of ESR1 1 0.07 0.9 0.04
110 INT206853 ESR1 Positive_regulation of Gene_expression of PCP4 1 0.08 1.39 0.04
111 INT206845 ANXA1 Regulation of Gene_expression of ESR1 1 0.07 0.9 0.04
112 INT201445 ESR1 Regulation of Slc6a3 1 0.02 0.05 0.04
113 INT206851 NR4A1 Regulation of Gene_expression of ESR1 1 0.08 0.9 0.04
114 INT236595 Binding of Esr1 and PELP1 1 0.27 0.17 0.04
115 INT206896 ESR1 Positive_regulation of Gene_expression of Nr1i3 1 0.00 0.36 0.04
116 INT206847 ESR1 Negative_regulation of Gene_expression of PTGER3 1 0.08 1.52 0.04
117 INT197917 Binding of ESR1 and Sh2b2 1 0.01 0 0.04
118 INT335703 Esr1 Regulation of Localization of Calr 1 0.03 0 0.04
119 INT213563 Binding of Ctnnd2 and Shh 1 0.27 0.09 0.04
120 INT270459 Binding of Shh and Gli1 1 0.02 0.65 0.04
121 INT206849 ESR1 Regulation of Gene_expression of ALDH1A1 1 0.11 2.26 0.04
122 INT206852 ESR1 Regulation of Gene_expression of CRABP2 1 0.08 1.52 0.04
123 INT183614 Binding of ESR1 and TMED4 2 0.02 0.13 0.03
124 INT278579 Esr1 Positive_regulation of Negative_regulation of Tac2 1 0.47 0.25 0.03
125 INT352014 Shh Positive_regulation of Gene_expression of Pax1 1 0.29 0.07 0.03
126 INT303558 Binding of Fgfr2 and Dysf 1 0.01 0.44 0.03
127 INT278289 Binding of DBP and ESR1 1 0.03 0.82 0.03
128 INT213902 ESR1 Positive_regulation of EGFR 1 0.48 0.31 0.03
129 INT331960 Positive_regulation of Binding of Esr1 and Tymp 1 0.00 0.15 0.03
130 INT331958 Binding of Esr1 and Tymp 1 0.00 0.15 0.03
131 INT245075 Binding of ESR1 and NR4A1 1 0.01 1.08 0.03
132 INT316773 Esr1 Positive_regulation of Ddit3 1 0.02 0.41 0.03
133 INT311655 Shh Positive_regulation of Gene_expression of Fgf8 1 0.31 0.18 0.03
134 INT270462 Shh Positive_regulation of Ccnd1 1 0.10 0.6 0.03
135 INT213559 Binding of Egf and Shh 1 0.17 0.07 0.03
136 INT278294 Binding of ESR1 and SHBG 1 0.01 0.82 0.03
137 INT221682 Binding of Esr1 and FRTS 1 0.01 0.15 0.03
138 INT213905 ESR1 Positive_regulation of SRC 1 0.14 0.31 0.03
139 INT215872 Atf4 Regulation of Esr1 1 0.30 0.42 0.03
140 INT192914 Binding of ESR1 and GOPC 2 0.02 0.61 0
141 INT260342 Binding of Esr1 and Rcc1 1 0.05 0.99 0
142 INT198111 Binding of Esr1 and Esr2 1 0.05 0 0
143 INT335214 Binding of ESR1 and RARS 1 0.08 0.92 0
144 INT178638 Gh1 Regulation of Gene_expression of ESR1 1 0.01 0.47 0
145 INT206895 Binding of ESR1 and Aldh1a1 1 0.03 0 0
146 INT264663 Binding of ESR1 and PRL 1 0.22 0.18 0
147 INT290910 Pkm2 Negative_regulation of Shh 1 0.07 0.06 0
148 INT98354 TXNRD1 Positive_regulation of Positive_regulation of ESR1 1 0.00 0.05 0
149 INT306500 Clu Regulation of Esr1 1 0.22 0.13 0
150 INT332958 Binding of Esr1 and Ppara 1 0.36 0.21 0
151 INT225559 Binding of Esr1 and Ncoa6 1 0.18 0 0
152 INT205963 GLI1 Positive_regulation of Negative_regulation of SHH 1 0.22 0.58 0
153 INT342281 Binding of INS and Esr1 1 0.08 0.57 0
154 INT206854 ESR1 Regulation of IGF1 1 0.01 0.33 0
155 INT314850 Shh Regulation of Atoh7 1 0.45 0.22 0
156 INT173771 Gh1 Regulation of Transcription of Esr1 1 0.00 0.13 0
157 INT189115 Binding of Esr1 and Tap1 1 0.07 0.05 0
158 INT120549 Binding of ESR1 and Mpo 1 0.26 0.05 0
159 INT199975 ESR1 Positive_regulation of PGR 1 0.05 0.11 0
160 INT290908 Regulation of Shh Positive_regulation of Ntn1 1 0.12 0 0
161 INT197677 Binding of ESR1 and Arg1 1 0.04 0 0
162 INT264662 ESR1 Regulation of Gene_expression of PRL 1 0.43 0.21 0
163 INT197615 Esr1 Regulation of Gene_expression of Pgr 1 0.01 0.21 0
164 INT176289 Pcna Positive_regulation of Phosphorylation of Esr1 1 0.01 0.67 0
165 INT336994 CALR Negative_regulation of ESR1 1 0.04 0 0
166 INT206850 Binding of CRABP2 and ESR1 1 0.06 0 0
167 INT290911 Gene_expression of Shh Positive_regulation of Pkm2 1 0.07 0 0
168 INT245077 Binding of ESR1 and CXCL12 1 0.06 1.42 0
169 INT191062 Esr1 Regulation of Gene_expression of Bcl2 1 0.12 0.73 0
170 INT313596 ESR1 Positive_regulation of Gene_expression of PGR 1 0.05 1 0
171 INT290904 Shh Positive_regulation of Prkcg 1 0.26 0.06 0
172 INT290900 Prkcg Regulation of Shh 1 0.23 0 0
173 INT219421 Binding of ESR1 and MALAT1 1 0.34 0.63 0
174 INT314740 Binding of ESR1 and Brca1 1 0.16 0.69 0
175 INT98353 THRB Negative_regulation of Positive_regulation of ESR1 1 0.00 0.09 0
176 INT191096 Negative_regulation of Binding of Apc and Esr1 1 0.05 1.07 0
177 INT208018 Col4a4 Regulation of Gene_expression of Esr1 1 0.06 0.69 0
178 INT224291 Negative_regulation of ESR1 Positive_regulation of CCND1 1 0.16 0.07 0
179 INT244457 CS Positive_regulation of Gene_expression of ESR1 1 0.07 0.67 0
180 INT192913 Binding of ESR1 and HAMP 1 0.02 0.72 0
181 INT314687 ESR1 Regulation of PGR 1 0.27 0.88 0
182 INT183091 Binding of FGF2 and FGFR2 1 0.03 0.79 0
183 INT197911 Dlst Positive_regulation of Gene_expression of Esr1 1 0.03 0.34 0
184 INT254435 Binding of Esr1 and Best1 1 0.21 0.06 0
185 INT205960 Binding of PTCH1 and SHH 1 0.21 0.71 0
186 INT333928 Binding of CALR and ESR1 1 0.09 0.09 0
187 INT225533 Binding of Emr1 and Esr1 1 0.01 0 0
188 INT333929 Binding of ESR1 and ERLEC1 1 0.01 0.09 0
189 INT223582 Negative_regulation of MTOR Positive_regulation of Phosphorylation of ESR1 1 0.31 0.67 0
190 INT290944 Shh Positive_regulation of VEGFA 1 0.04 0.05 0
191 INT178639 Binding of ESR1 and Igf1 1 0.02 0.39 0
192 INT197908 Dlst Positive_regulation of Esr1 1 0.03 0.34 0
193 INT244450 TMBIM6 Negative_regulation of Gene_expression of ESR1 1 0.04 0.68 0
194 INT270461 Shh Regulation of Gene_expression of Ptch1 1 0.48 0.07 0
195 INT225621 Positive_regulation of Binding of TARBP2 and Esr1 1 0.03 0 0
196 INT225531 R3hcc1 Positive_regulation of Positive_regulation of Esr1 1 0.00 0 0
197 INT197614 Esr1 Regulation of Pgr 1 0.01 0.07 0
198 INT260601 Binding of ESR1 and Ppargc1a 1 0.01 0.48 0
199 INT206844 ESR1 Positive_regulation of Gene_expression of ANXA1 1 0.08 0.1 0
200 INT264661 ESR1 Positive_regulation of PRL 1 0.43 0.68 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for prostate epithelial cord elongation. They are ordered first by their pain relevance and then by number of times they were reported in prostate epithelial cord elongation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34
2 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64
3 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81
4 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69
5 INT37296 Binding of Esr1 117 0.43 62.51 27.33
6 INT20462 Binding of ESR1 210 0.44 102.7 26.34
7 INT823 Negative_regulation of ESR1 144 0.58 63.72 22.52
8 INT4067 Negative_regulation of Esr1 97 0.50 43.45 17.52
9 INT17237 Regulation of Esr1 74 0.43 49.09 17.25
10 INT92354 Localization of ESR1 77 0.75 33.04 15.51
11 INT73916 Gene_expression of Esr1 58 0.77 26.59 15.15
12 INT2038 Localization of Esr1 104 0.79 40.12 13.27
13 INT79545 Positive_regulation of Gene_expression of ESR1 82 0.64 39.42 12.18
14 INT15687 Regulation of ESR1 91 0.60 40.42 7.95
15 INT110987 Transcription of ESR1 45 0.71 24.16 6.72
16 INT22901 Negative_regulation of Gene_expression of Esr1 30 0.42 20.92 6.29
17 INT20280 Positive_regulation of Esr1 32 0.69 18.37 5.69
18 INT43997 Positive_regulation of Gene_expression of Esr1 57 0.51 36.66 5.51
19 INT16621 Negative_regulation of Esr1 20 0.54 8.2 4.84
20 INT133630 Negative_regulation of Gene_expression of ESR1 42 0.52 23.89 4.57
21 INT117205 Transcription of Esr1 23 0.65 9.4 4.14
22 INT218955 Protein_catabolism of ESR1 9 0.92 3.95 3.74
23 INT20461 Binding of Esr1 34 0.48 9.58 3.66
24 INT178631 Phosphorylation of ESR1 21 0.75 9.16 3.36
25 INT73918 Transcription of Esr1 21 0.66 8.74 3.12
26 INT31541 Regulation of Esr1 15 0.54 4.12 2.82
27 INT174727 Positive_regulation of Positive_regulation of ESR1 14 0.44 6.3 2.7
28 INT144973 Gene_expression of Shh 9 0.77 4.32 1.96
29 INT73913 Regulation of Gene_expression of Esr1 2 0.41 2.24 1.92
30 INT218959 Negative_regulation of Protein_catabolism of ESR1 3 0.37 0.97 1.9
31 INT208561 Gene_expression of Shh 51 0.78 9.57 1.77
32 INT96971 Positive_regulation of Gene_expression of Esr1 6 0.46 2.27 1.67
33 INT222089 Positive_regulation of Localization of Esr1 19 0.49 8.73 1.58
34 INT8511 Localization of Esr1 6 0.80 3.27 1.26
35 INT128752 Negative_regulation of Localization of Esr1 11 0.43 4.8 1.23
36 INT824 Negative_regulation of Negative_regulation of ESR1 3 0.42 1.53 1.18
37 INT253191 Positive_regulation of Gene_expression of Shh 2 0.66 2.57 1.14
38 INT76890 Gene_expression of FGFR2 42 0.65 13.91 1.08
39 INT81945 Negative_regulation of Binding of Esr1 3 0.32 0.55 1.06
40 INT165530 Positive_regulation of Shh 4 0.69 1.21 1.05
41 INT71906 Regulation of Gene_expression of ESR1 22 0.41 11.01 0.98
42 INT154468 Negative_regulation of Transcription of ESR1 3 0.29 1.14 0.96
43 INT173747 Regulation of Positive_regulation of Esr1 4 0.37 4.85 0.95
44 INT236576 Positive_regulation of Binding of Esr1 3 0.41 2.39 0.92
45 INT154465 Negative_regulation of Transcription of Esr1 1 0.05 0 0.92
46 INT128755 Protein_catabolism of Esr1 10 0.57 4.61 0.9
47 INT73914 Negative_regulation of Transcription of Esr1 3 0.39 0.75 0.84
48 INT183182 Negative_regulation of FGFR2 2 0.29 1.25 0.84
49 INT174728 Positive_regulation of Transcription of ESR1 10 0.47 3.3 0.83
50 INT125092 Negative_regulation of Binding of ESR1 8 0.42 4.15 0.82
51 INT33818 Positive_regulation of Negative_regulation of Esr1 3 0.40 0.98 0.82
52 INT161778 Regulation of Gene_expression of Esr1 13 0.51 9.46 0.73
53 INT92082 Regulation of Binding of ESR1 5 0.45 2.41 0.73
54 INT239494 Regulation of Localization of Esr1 4 0.19 1.15 0.72
55 INT73917 Regulation of Transcription of Esr1 4 0.25 1.5 0.7
56 INT191177 Regulation of Localization of ESR1 7 0.42 2.04 0.64
57 INT158136 Binding of FGFR2 9 0.26 4.5 0.63
58 INT9836 Negative_regulation of Negative_regulation of Esr1 3 0.29 0.95 0.63
59 INT173748 Phosphorylation of Esr1 11 0.77 5.7 0.55
60 INT173744 Positive_regulation of Positive_regulation of Esr1 10 0.43 7.05 0.52
61 INT190899 Negative_regulation of Phosphorylation of ESR1 3 0.33 1.01 0.49
62 INT146778 Negative_regulation of Fgfr2 1 0.32 0.66 0.48
63 INT240710 Positive_regulation of Regulation of Esr1 1 0.09 1.34 0.47
64 INT206484 Localization of Shh 2 0.75 1.14 0.46
65 INT232798 Positive_regulation of Gene_expression of Shh 7 0.70 1.49 0.44
66 INT202626 Negative_regulation of Fgfr2 2 0.41 2.48 0.42
67 INT174725 Positive_regulation of Localization of ESR1 8 0.47 2.45 0.41
68 INT208559 Negative_regulation of Gene_expression of Shh 8 0.43 1.58 0.38
69 INT268930 Regulation of Regulation of Esr1 2 0.41 0.48 0.38
70 INT178630 Positive_regulation of Negative_regulation of ESR1 2 0.04 0.64 0.35
71 INT236580 Regulation of Binding of Esr1 4 0.39 1.1 0.34
72 INT176586 Positive_regulation of Binding of ESR1 11 0.41 4.64 0.33
73 INT183916 Negative_regulation of Binding of Esr1 1 0.06 0.91 0.32
74 INT192845 Negative_regulation of Positive_regulation of Esr1 2 0.35 1.15 0.31
75 INT73915 Negative_regulation of Negative_regulation of Esr1 1 0.40 0.06 0.31
76 INT153772 Negative_regulation of Localization of ESR1 7 0.54 4.42 0.27
77 INT232795 Positive_regulation of Shh 2 0.70 3.68 0.26
78 INT176080 Gene_expression of Fgfr2 4 0.68 2.34 0.24
79 INT223739 Binding of Fgfr2 3 0.30 0.94 0.22
80 INT183062 Gene_expression of SHH 12 0.65 5.28 0.21
81 INT96972 Positive_regulation of Binding of Esr1 4 0.22 1.35 0.21
82 INT134477 Negative_regulation of SHH 2 0.37 1.13 0.2
83 INT186021 Positive_regulation of Positive_regulation of Esr1 1 0.08 0 0.19
84 INT176571 Negative_regulation of Positive_regulation of ESR1 5 0.47 3.15 0.17
85 INT291955 Positive_regulation of Protein_catabolism of Esr1 1 0.06 0.14 0.17
86 INT232799 Regulation of Gene_expression of Shh 3 0.27 1.04 0.16
87 INT269777 Regulation of Regulation of Esr1 2 0.02 1.17 0.16
88 INT253177 Negative_regulation of Gene_expression of Shh 2 0.55 0.63 0.16
89 INT176461 Protein_catabolism of Esr1 1 0.12 0.37 0.16
90 INT183400 Positive_regulation of Transcription of Esr1 4 0.30 1.06 0.14
91 INT253190 Localization of Shh 2 0.77 1.06 0.13
92 INT99718 Positive_regulation of Gene_expression of FGFR2 9 0.49 4.47 0.12
93 INT253183 Negative_regulation of Shh 8 0.55 2.13 0.12
94 INT162109 Negative_regulation of Gene_expression of Esr1 4 0.16 2.41 0.12
95 INT232556 Positive_regulation of Phosphorylation of Esr1 1 0.20 0.41 0.12
96 INT270442 Transcription of Shh 1 0.53 0.25 0.09
97 INT213515 Binding of Shh 8 0.37 1.92 0.08
98 INT270453 Regulation of Shh 1 0.27 0.83 0.08
99 INT224299 Positive_regulation of Protein_catabolism of ESR1 3 0.64 1.43 0.07
100 INT205973 Binding of SHH 3 0.35 1.03 0.07
101 INT256862 Regulation of Shh 1 0.25 0 0.07
102 INT178868 Regulation of Positive_regulation of ESR1 1 0.42 0.52 0.07
103 INT253882 Positive_regulation of Localization of Esr1 1 0.30 1.21 0.06
104 INT303546 Binding of Fgfr2 1 0.46 0.74 0.06
105 INT270445 Positive_regulation of Localization of Shh 1 0.44 0.13 0.05
106 INT181793 Positive_regulation of SHH 3 0.67 2.59 0.04
107 INT208560 Negative_regulation of Shh 2 0.59 2.22 0.04
108 INT272379 Positive_regulation of Transcription of Esr1 1 0.04 0.13 0.04
109 INT303525 Localization of Fgfr2 1 0.72 0.28 0.03
110 INT253187 Negative_regulation of Transcription of Shh 1 0.41 0.55 0.03
111 INT221677 Negative_regulation of Protein_catabolism of Esr1 1 0.08 0.15 0.03
112 INT303547 Positive_regulation of Negative_regulation of Fgfr2 1 0.48 1.07 0.03
113 INT253181 Transcription of Shh 1 0.68 0.54 0.03
114 INT174726 Regulation of Regulation of ESR1 1 0.41 0.73 0.03
115 INT207729 Regulation of FGFR2 4 0.22 2.35 0
116 INT238985 Positive_regulation of FGFR2 3 0.49 1.19 0
117 INT99716 Transcription of FGFR2 2 0.34 0.22 0
118 INT305351 Positive_regulation of Regulation of FGFR2 2 0.37 0.97 0
119 INT99715 Regulation of Gene_expression of FGFR2 2 0.22 0.19 0
120 INT174724 Regulation of Transcription of ESR1 2 0.18 0.49 0
121 INT303555 Negative_regulation of Gene_expression of FGFR2 2 0.41 0.31 0
122 INT178629 Positive_regulation of Phosphorylation of ESR1 2 0.36 0.93 0
123 INT202623 Negative_regulation of Gene_expression of Fgfr2 1 0.32 0 0
124 INT319036 Gene_expression of Fgfr2 1 0.48 0.08 0
125 INT335681 Regulation of Negative_regulation of Esr1 1 0.03 0 0
126 INT173746 Regulation of Transcription of Esr1 1 0.04 0 0
127 INT290918 Negative_regulation of Positive_regulation of Shh 1 0.41 0.25 0
128 INT223607 Regulation of Phosphorylation of ESR1 1 0.35 0.65 0
129 INT99717 Positive_regulation of Transcription of FGFR2 1 0.10 0.08 0
130 INT183117 Positive_regulation of Binding of FGFR2 1 0.09 0.81 0
131 INT230972 Positive_regulation of Gene_expression of SHH 1 0.18 0.07 0
132 INT290929 Binding of Shh 1 0.31 0.1 0
133 INT290927 Regulation of Positive_regulation of Shh 1 0.23 0 0
134 INT303524 Positive_regulation of Fgfr2 1 0.66 0.22 0
135 INT270449 Negative_regulation of Positive_regulation of Shh 1 0.43 0.24 0
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