GO:0060539

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Name diaphragm development
Categary Process
Go Slim No
Go Link GO:0060539
Unique Molecular Interactions 48
Total Molecular Interactions 54
Total Single Events 648
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for diaphragm development. They are ordered first by their pain relevance and then by number of times they were reported for diaphragm development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT281373 Tcf21 Regulation of Fig4 1 0.03 0.67 1.2
2 INT281379 Tcf21 Regulation of FSCN1 1 0.01 0.66 1.19
3 INT316128 TCF21 Negative_regulation of Gene_expression of HLA-DRA 1 0.07 0.13 0.99
4 INT222246 Binding of Ccr2 and Tcf21 1 0.29 0.67 0.55
5 INT222249 Positive_regulation of Binding of Ccr2 and Tcf21 1 0.39 0.67 0.55
6 INT281124 Tcf21 Positive_regulation of Binding of Ddc 1 0.04 1.21 0.54
7 INT281129 Tcf21 Positive_regulation of Binding of Cd4 1 0.04 1.21 0.54
8 INT281152 Tcf21 Positive_regulation of Binding of ITIH4 1 0.03 1.21 0.54
9 INT281131 Tcf21 Positive_regulation of Rent1 1 0.00 1.19 0.53
10 INT281374 Tcf21 Positive_regulation of Gene_expression of Sds 1 0.03 0 0.51
11 INT222251 Negative_regulation of Binding of Cxcl10 and Tcf21 1 0.23 0.34 0.32
12 INT222247 Binding of Cxcl10 and Tcf21 1 0.20 0.34 0.32
13 INT281127 Tcf21 Positive_regulation of Gene_expression of Cxcr4 1 0.08 0.42 0.3
14 INT265603 Msc Positive_regulation of Gene_expression of Il6 1 0.16 1.79 0.2
15 INT333652 Binding of Ccr5 and Msc 1 0.10 0.07 0.13
16 INT333653 Binding of Msc and Tg(CAG-EGFP)D4Nagy 1 0.01 0.07 0.13
17 INT304813 Binding of MNX1 and RT1-CE1 1 0.00 0.34 0.1
18 INT239559 MSC Regulation of Gene_expression of BDNF 1 0.05 1 0.09
19 INT265609 Msc Positive_regulation of TAF8 1 0.03 0.7 0.08
20 INT343792 Binding of TCF21 and CORO7 1 0.01 0.51 0.07
21 INT168976 Binding of Wt1 and Calb2 1 0.01 1.39 0.07
22 INT22568 Cyp1a1 Positive_regulation of Tcf21 1 0.04 0 0.06
23 INT315969 Binding of Lipg and Msc 1 0.01 0.14 0.06
24 INT22567 Cyp1a2 Positive_regulation of Tcf21 1 0.04 0 0.06
25 INT181601 Binding of TP53 and WT1 1 0.30 0.9 0.05
26 INT239560 MSC Regulation of Gene_expression of IFN1@ 1 0.11 0.87 0.04
27 INT276583 Binding of Wt1 and IgG 1 0.07 0 0.04
28 INT347163 NOTCH1 Positive_regulation of MSC 1 0.03 0.85 0.03
29 INT265610 Positive_regulation of TAF8 Positive_regulation of Msc 1 0.03 0.89 0
30 INT276586 Binding of Wt1 and Actn1 1 0.34 0.41 0
31 INT278242 MSC Regulation of Gene_expression of Cd36 1 0.08 1.17 0
32 INT181599 Binding of EWSR1 and WT1 1 0.40 0.29 0
33 INT276590 Binding of Wt1 and KTWS 1 0.02 0.3 0
34 INT278229 MSC Positive_regulation of Gene_expression of ALB 1 0.06 0.3 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for diaphragm development. They are ordered first by their pain relevance and then by number of times they were reported in diaphragm development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT215353 Gene_expression of Tcf21 16 0.59 9.71 9.49
2 INT28122 Gene_expression of MSC 111 0.58 26.83 6.57
3 INT72834 Negative_regulation of Tcf21 10 0.58 5.8 4.84
4 INT38066 Binding of MSC 14 0.41 5.28 4.12
5 INT22566 Positive_regulation of Tcf21 8 0.65 3.06 3.75
6 INT9144 Localization of MSC 18 0.56 10.17 3.69
7 INT37715 Positive_regulation of MSC 34 0.48 10.52 2.92
8 INT281367 Regulation of Gene_expression of Tcf21 1 0.09 1.39 2.89
9 INT281369 Negative_regulation of Gene_expression of Tcf21 1 0.08 1.4 2.44
10 INT90004 Gene_expression of TCF21 4 0.65 2.48 2.02
11 INT173641 Regulation of MSC 13 0.39 2.85 1.82
12 INT316162 Localization of TCF21 1 0.18 0.28 1.71
13 INT28123 Positive_regulation of Gene_expression of MSC 17 0.43 4.02 1.54
14 INT254330 Regulation of Msc 10 0.16 7.59 1.46
15 INT222228 Positive_regulation of Gene_expression of Tcf21 4 0.38 0.84 1.39
16 INT110485 Binding of Tcf21 2 0.36 0.76 1.37
17 INT203491 Gene_expression of Msc 40 0.64 36.05 1.35
18 INT38067 Transcription of MSC 1 0.55 0.55 1.25
19 INT316154 Positive_regulation of TCF21 4 0.17 1.22 1.23
20 INT332771 Phosphorylation of Tcf21 1 0.09 0.21 1.07
21 INT332772 Positive_regulation of Phosphorylation of Tcf21 1 0.06 0.21 1.07
22 INT230633 Positive_regulation of MNX1 3 0.30 1.4 0.97
23 INT102677 Negative_regulation of TCF21 2 0.41 0.22 0.89
24 INT173626 Negative_regulation of MSC 9 0.47 3.28 0.87
25 INT181812 Positive_regulation of Msc 20 0.66 13.47 0.86
26 INT305483 Negative_regulation of MNX1 1 0.04 0.73 0.82
27 INT101209 Gene_expression of Wt1 19 0.72 25.77 0.7
28 INT183037 Gene_expression of MNX1 12 0.53 4.27 0.69
29 INT140874 Binding of MNX1 4 0.36 0.85 0.69
30 INT193196 Regulation of MNX1 2 0.19 2.53 0.64
31 INT13724 Positive_regulation of WT1 5 0.69 4.99 0.59
32 INT281366 Regulation of Tcf21 1 0.09 0.23 0.59
33 INT88694 Gene_expression of WT1 17 0.75 21.88 0.56
34 INT316161 Negative_regulation of Gene_expression of TCF21 1 0.10 0.11 0.56
35 INT222229 Localization of Tcf21 1 0.57 0.45 0.45
36 INT265575 Binding of Msc 11 0.30 7.66 0.34
37 INT294134 Regulation of Negative_regulation of MSC 1 0.05 0.51 0.3
38 INT265583 Localization of Msc 7 0.61 6.37 0.25
39 INT114703 Positive_regulation of Wt1 5 0.46 4.25 0.24
40 INT230622 Negative_regulation of Gene_expression of MNX1 3 0.26 0.61 0.22
41 INT154282 Positive_regulation of Gene_expression of WT1 3 0.55 3.41 0.19
42 INT13723 Negative_regulation of Positive_regulation of WT1 1 0.03 1.26 0.17
43 INT319048 Transcription of WT1 2 0.56 1.87 0.16
44 INT101208 Positive_regulation of Gene_expression of Wt1 3 0.47 3.08 0.15
45 INT315967 Negative_regulation of Msc 3 0.35 1.86 0.15
46 INT265584 Positive_regulation of Localization of Msc 2 0.20 1.49 0.15
47 INT279393 Regulation of Gene_expression of MSC 2 0.07 0.36 0.14
48 INT265573 Positive_regulation of Gene_expression of Msc 4 0.41 6.78 0.12
49 INT178195 Localization of Wt1 4 0.69 2.64 0.1
50 INT183057 Positive_regulation of Gene_expression of MNX1 2 0.38 0.75 0.1
51 INT352543 Phosphorylation of MSC 1 0.31 0.59 0.1
52 INT168975 Binding of Wt1 14 0.43 7.37 0.07
53 INT166389 Binding of WT1 7 0.36 8.25 0.07
54 INT265571 Negative_regulation of Gene_expression of Msc 2 0.17 1.46 0.07
55 INT314368 Transcription of Msc 3 0.56 1.97 0.05
56 INT307902 Negative_regulation of Localization of Wt1 1 0.34 0.21 0.05
57 INT278240 Positive_regulation of Binding of MSC 1 0.23 0.1 0.05
58 INT265572 Regulation of Gene_expression of Msc 4 0.37 6.82 0.03
59 INT193195 Localization of MNX1 1 0.59 1.01 0.03
60 INT181604 Localization of WT1 1 0.63 1.41 0.03
61 INT285960 Negative_regulation of WT1 6 0.47 10.02 0
62 INT276530 Negative_regulation of Wt1 5 0.53 2.97 0
63 INT285959 Negative_regulation of Gene_expression of WT1 3 0.46 4.9 0
64 INT265581 Positive_regulation of Positive_regulation of Msc 2 0.19 2.01 0
65 INT276519 Regulation of Wt1 2 0.24 1.7 0
66 INT276550 Transcription of Wt1 2 0.66 1.35 0
67 INT276547 Positive_regulation of Binding of Wt1 1 0.63 0.29 0
68 INT307906 Negative_regulation of Transcription of Wt1 1 0.54 1.3 0
69 INT205437 Regulation of Positive_regulation of MSC 1 0.27 0.12 0
70 INT276551 Positive_regulation of Localization of Wt1 1 0.45 0 0
71 INT315964 Positive_regulation of Transcription of Msc 1 0.41 1.33 0
72 INT276534 Negative_regulation of Binding of Wt1 1 0.38 0 0
73 INT319051 Regulation of Positive_regulation of WT1 1 0.36 1.11 0
74 INT307903 Negative_regulation of Gene_expression of Wt1 1 0.39 1.31 0
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