GO:0060547

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Name negative regulation of necrotic cell death
Categary Process
Go Slim No
Go Link GO:0060547
Unique Molecular Interactions 95
Total Molecular Interactions 137
Total Single Events 1280
Pain Genes Associated 11

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of necrotic cell death. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of necrotic cell death. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT22726 Positive_regulation of Ahr Positive_regulation of Hrtrt1 1 0.22 0.18 0.95
2 INT22725 Ahr Positive_regulation of Hrtrt1 1 0.22 0.18 0.95
3 INT62109 SLC25A4 Negative_regulation of Localization of Gh 1 0.06 0 0.94
4 INT62111 SLC25A4 Negative_regulation of Regulation of Ghrh 1 0.41 0 0.9
5 INT193279 Phax Regulation of Fth1 1 0.01 0.16 0.81
6 INT16048 MAX Positive_regulation of SLC25A4 1 0.50 0 0.71
7 INT303691 KNG1 Positive_regulation of AHR 1 0.03 0.98 0.69
8 INT303689 Regulation of KNG1 Positive_regulation of AHR 1 0.03 0.99 0.69
9 INT193290 CAP1 Regulation of Fth1 1 0.02 0 0.6
10 INT208372 Il13 Positive_regulation of Ahr 1 0.21 1.22 0.59
11 INT147575 Binding of Ahr and Cyp1a1 2 0.15 0.15 0.54
12 INT55445 Positive_regulation of Ahr Regulation of Mme 1 0.23 0 0.53
13 INT147576 Positive_regulation of Ahr Positive_regulation of Gene_expression of Scrg1 1 0.00 0.17 0.52
14 INT162500 AHR Regulation of CYP1A1 3 0.19 0.18 0.51
15 INT162503 AHR Regulation of CYP1A2 3 0.61 0.18 0.5
16 INT162499 Binding of AHR and NEUROD1 3 0.25 0.19 0.49
17 INT115914 AHR Regulation of Gene_expression of PPIG 1 0.25 0.36 0.44
18 INT115916 AHR Regulation of Gene_expression of SLC45A2 1 0.64 0.36 0.44
19 INT115915 AHR Regulation of Gene_expression of CYP2B6 1 0.06 0.36 0.43
20 INT108732 Gene_expression of Gstp1 Positive_regulation of Gene_expression of Mgst1 1 0.44 0.58 0.41
21 INT223829 Binding of GSTM1 and GSTP1 2 0.41 2.78 0.39
22 INT62110 SLC25A4 Negative_regulation of Regulation of Gh 1 0.06 0 0.39
23 INT104932 AHR Positive_regulation of CYP1A1 1 0.43 0.83 0.31
24 INT279959 Tnfrsf1b Negative_regulation of Ahr 1 0.10 0.98 0.24
25 INT179186 Fcer2a Regulation of Positive_regulation of Ahr 1 0.05 1.23 0.23
26 INT223828 Binding of GSTP1 and MAPK8 1 0.06 1.8 0.21
27 INT304104 Il13 Positive_regulation of Positive_regulation of AHR 1 0.14 2.6 0.19
28 INT188921 Binding of Pc and Ahr 1 0.12 0 0.19
29 INT188920 Pc Positive_regulation of Ahr 1 0.14 0 0.18
30 INT134196 Ahr Regulation of Transcription of Cyp1a1 1 0.11 0.14 0.16
31 INT134202 Ahr Regulation of AHR 1 0.18 0.13 0.16
32 INT139538 Binding of CD34 and KIT 2 0.39 2.73 0.14
33 INT153785 AHR Regulation of UGT1A3 1 0.69 0.07 0.14
34 INT36376 Binding of AHR and FUT4 1 0.01 0.9 0.14
35 INT304094 Binding of AHR and SNRNP70 1 0.00 2.64 0.14
36 INT95103 TGFBR2 Positive_regulation of CD34 1 0.11 0.61 0.14
37 INT148594 Binding of BCL2 and CD34 1 0.39 1.17 0.13
38 INT338419 Il13 Regulation of Positive_regulation of Ahr 1 0.04 0.54 0.13
39 INT36373 Binding of AHR and INSL3 1 0.00 0.5 0.12
40 INT277986 Negative_regulation of Epo Positive_regulation of Localization of Cd34 1 0.08 0.77 0.12
41 INT285030 Binding of Bax and Slc25a4 1 0.03 0.84 0.11
42 INT336632 Ecm1 Regulation of Regulation of Ahr 1 0.03 0.61 0.11
43 INT325222 Il13 Regulation of Ahr 1 0.21 0.58 0.11
44 INT227061 Binding of Ahr and Alb 1 0.23 0.08 0.1
45 INT118052 Binding of Pecam1 and Cd34 1 0.22 0.51 0.1
46 INT223827 MAPK8 Positive_regulation of Gene_expression of GSTP1 1 0.12 0.88 0.1
47 INT134201 Positive_regulation of Binding of AHR and Cyp1a1 1 0.21 0.07 0.1
48 INT134200 Binding of AHR and Cyp1a1 1 0.16 0.07 0.1
49 INT299953 Binding of CD34 and FTSJ3 1 0.04 1.07 0.09
50 INT278164 GSTM1 Positive_regulation of Transcription of GSTP1 1 0.57 0.94 0.07
51 INT36372 Binding of AHR and KLF1 1 0.00 0.45 0.07
52 INT302985 HIVEP1 Positive_regulation of Positive_regulation of AHR 1 0.06 0.5 0.06
53 INT209615 Binding of KRT20 and Cd34 1 0.00 1.05 0.06
54 INT209611 Binding of Mme and Cd34 1 0.00 1.05 0.06
55 INT302984 MBP Positive_regulation of AHR 1 0.31 0.3 0.06
56 INT223825 GSTP1 Negative_regulation of MAPK8 1 0.11 1.53 0.06
57 INT118227 Binding of ACTG2 and CD34 1 0.15 1.17 0.06
58 INT209610 Binding of Cd22 and Cd34 1 0.01 1.05 0.06
59 INT222544 Binding of Ucn and Crh 1 0.02 0 0.05
60 INT218009 AHR Positive_regulation of CYP27B1 1 0.16 0.06 0.05
61 INT285388 Ahr Positive_regulation of Gene_expression of Cyp27b1 1 0.01 0.14 0.04
62 INT222417 Ucn Positive_regulation of Localization of Pomc 1 0.01 0 0.04
63 INT218011 AHR Positive_regulation of Transcription of CYP27B1 1 0.16 0 0.04
64 INT285386 Ahr Positive_regulation of Binding of Cyp27b1 1 0.01 0.14 0.04
65 INT197296 Ahr Regulation of Bhlha15 1 0.48 0.47 0.03
66 INT222469 Binding of Ucn and Crhr2 1 0.00 0 0.03
67 INT219423 Binding of AHR and ARNT 4 0.24 0.46 0
68 INT219418 ARNT Positive_regulation of Localization of AHR 1 0.25 0 0
69 INT308314 Binding of CD34 and Pfpl 1 0.03 0.57 0
70 INT340275 NFATC1 Positive_regulation of Binding of Ahr 1 0.10 0.51 0
71 INT219503 Binding of AHR and Ppib 1 0.27 0 0
72 INT219406 AHR Positive_regulation of CBL 1 0.03 0.65 0
73 INT189127 Mch Positive_regulation of Ahr 1 0.18 0.29 0
74 INT249850 Binding of Ptprc and Cd34 1 0.13 0.48 0
75 INT197304 Ahr Regulation of Hes1 1 0.06 0.17 0
76 INT347035 Binding of Kit and Cd34 1 0.02 1.38 0
77 INT197295 Positive_regulation of Binding of Ahr and Cyp1a1 1 0.20 0 0
78 INT290218 Binding of SLC25A4 and FSHMD1A 1 0.22 0.98 0
79 INT219504 AHR Regulation of Gene_expression of Ppib 1 0.21 1.12 0
80 INT186889 Binding of AHR and PC 1 0.05 1.06 0
81 INT353194 ARNTL Regulation of Localization of Ahr 1 0.27 0.32 0
82 INT213744 Binding of Cd34 and Epc1 1 0.12 0 0
83 INT219424 Binding of AHR and TSPO 1 0.01 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of necrotic cell death. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of necrotic cell death. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT24876 Gene_expression of CD34 172 0.78 91.02 12.39
2 INT49325 Gene_expression of Cd34 102 0.78 82.75 8.97
3 INT90603 Positive_regulation of Ahr 103 0.69 58.65 7.73
4 INT14166 Positive_regulation of Ahr 32 0.61 20.78 7.47
5 INT14165 Negative_regulation of Ahr 14 0.51 8.35 4.17
6 INT21681 Positive_regulation of CD34 54 0.66 33.95 4.14
7 INT115921 Positive_regulation of AHR 22 0.49 12.03 3.53
8 INT67379 Positive_regulation of Cd34 38 0.58 26.18 3.28
9 INT147572 Gene_expression of Ahr 73 0.75 38.99 3.15
10 INT47207 Negative_regulation of Ahr 25 0.52 16.11 3.02
11 INT44661 Regulation of Ahr 15 0.45 12.69 2.79
12 INT96876 Gene_expression of AHR 20 0.77 10.43 2.39
13 INT135077 Binding of GSTP1 11 0.48 7.03 1.8
14 INT96877 Transcription of AHR 7 0.62 3.25 1.77
15 INT134197 Regulation of AHR 11 0.44 4.82 1.76
16 INT14167 Negative_regulation of Positive_regulation of Ahr 5 0.51 1.54 1.71
17 INT80162 Localization of Ucn 6 0.80 0.6 1.66
18 INT17094 Negative_regulation of SLC25A4 3 0.41 3.82 1.52
19 INT21682 Binding of CD34 18 0.47 13.19 1.47
20 INT36389 Binding of AHR 18 0.45 7.22 1.46
21 INT90604 Positive_regulation of Positive_regulation of Ahr 8 0.45 3.52 1.45
22 INT54805 Regulation of Ahr 7 0.22 4.14 1.41
23 INT3816 Gene_expression of Ahr 13 0.65 7.51 1.31
24 INT29693 Binding of Ahr 11 0.31 13.27 1.23
25 INT45079 Binding of Ahr 21 0.44 10.07 1
26 INT119168 Negative_regulation of Cd34 8 0.37 4.91 0.96
27 INT126967 Localization of Cd34 9 0.79 3.69 0.87
28 INT96188 Binding of Cd34 11 0.31 10.4 0.82
29 INT80159 Gene_expression of Ucn 3 0.67 0.47 0.82
30 INT55560 Binding of SLC25A4 8 0.36 1.94 0.79
31 INT208367 Regulation of Localization of Ahr 1 0.30 1.6 0.67
32 INT208371 Localization of Ahr 2 0.50 1.9 0.66
33 INT129006 Negative_regulation of Gstp1 1 0.34 1.85 0.65
34 INT172204 Gene_expression of SLC25A4 8 0.70 4.11 0.62
35 INT114942 Negative_regulation of Positive_regulation of Ahr 5 0.55 2.65 0.62
36 INT94713 Regulation of CD34 11 0.45 8.02 0.58
37 INT128472 Negative_regulation of CD34 7 0.42 3.92 0.58
38 INT64096 Negative_regulation of AHR 5 0.37 1.2 0.58
39 INT19047 Localization of SLC25A4 5 0.73 2.73 0.57
40 INT80160 Negative_regulation of Ucn 2 0.58 0.29 0.56
41 INT106022 Negative_regulation of GSTP1 5 0.59 2.12 0.55
42 INT120762 Regulation of GSTP1 2 0.45 3.66 0.54
43 INT147571 Regulation of Binding of Ahr 1 0.26 0.15 0.54
44 INT104935 Localization of AHR 6 0.74 2.54 0.53
45 INT186728 Negative_regulation of Positive_regulation of AHR 1 0.08 1.61 0.52
46 INT80163 Positive_regulation of Gene_expression of Ucn 1 0.50 0.41 0.52
47 INT196003 Regulation of Cd34 4 0.30 3.38 0.5
48 INT95328 Gene_expression of Gstp1 11 0.61 8.59 0.48
49 INT87819 Localization of CD34 21 0.81 7.69 0.47
50 INT119251 Positive_regulation of Gene_expression of CD34 12 0.49 5.2 0.44
51 INT94035 Transcription of Ahr 1 0.53 0.53 0.43
52 INT123831 Regulation of Ucn 2 0.42 0 0.42
53 INT45887 Positive_regulation of SLC25A4 2 0.45 0.9 0.4
54 INT325423 Localization of Gstp1 1 0.06 0.85 0.37
55 INT325425 Positive_regulation of Localization of Gstp1 1 0.04 0.9 0.37
56 INT279958 Regulation of Regulation of Ahr 1 0.29 1.32 0.37
57 INT197286 Positive_regulation of Gene_expression of Ahr 10 0.67 9.78 0.36
58 INT87406 Gene_expression of GSTP1 16 0.77 11.37 0.35
59 INT232153 Regulation of Negative_regulation of Cd34 1 0.05 0.07 0.35
60 INT96871 Regulation of Transcription of AHR 2 0.41 0.46 0.33
61 INT144474 Protein_catabolism of Gstp1 1 0.06 0.57 0.33
62 INT199762 Positive_regulation of Gstp1 2 0.55 2.02 0.32
63 INT115922 Negative_regulation of Binding of AHR 1 0.40 0.12 0.32
64 INT62108 Positive_regulation of Localization of SLC25A4 1 0.49 0 0.31
65 INT153731 Positive_regulation of Gene_expression of Ahr 2 0.32 2 0.28
66 INT122676 Positive_regulation of Ucn 1 0.43 0.92 0.26
67 INT55443 Positive_regulation of Positive_regulation of Ahr 1 0.40 0 0.26
68 INT278169 Regulation of Regulation of GSTP1 1 0.45 1.1 0.25
69 INT232504 Negative_regulation of Gene_expression of CD34 4 0.38 1.89 0.23
70 INT320213 Regulation of SLC25A4 1 0.21 0.22 0.23
71 INT96869 Positive_regulation of Gene_expression of AHR 1 0.45 0.43 0.23
72 INT199771 Localization of Ahr 8 0.70 4.86 0.2
73 INT120761 Positive_regulation of GSTP1 3 0.50 3.4 0.19
74 INT96875 Regulation of Gene_expression of AHR 1 0.25 0.38 0.18
75 INT320212 Regulation of Positive_regulation of SLC25A4 1 0.40 0.13 0.17
76 INT134193 Regulation of Regulation of Ahr 1 0.12 0.14 0.16
77 INT135706 Negative_regulation of Binding of CD34 1 0.40 1.19 0.16
78 INT137457 Positive_regulation of Localization of Cd34 1 0.46 0.55 0.16
79 INT289312 Phosphorylation of Ahr 1 0.03 0.86 0.15
80 INT153787 Positive_regulation of Transcription of AHR 1 0.45 0.08 0.15
81 INT294583 Negative_regulation of Gene_expression of Ahr 2 0.38 1.01 0.14
82 INT134194 Regulation of Gene_expression of Ahr 1 0.12 0.17 0.14
83 INT232508 Regulation of Gene_expression of CD34 4 0.43 2.73 0.13
84 INT278171 Positive_regulation of Transcription of GSTP1 1 0.50 1.86 0.13
85 INT197287 Regulation of Gene_expression of Ahr 5 0.45 1 0.11
86 INT302699 Negative_regulation of Localization of SLC25A4 1 0.38 1.01 0.11
87 INT223834 Localization of GSTP1 2 0.70 1.28 0.1
88 INT285011 Binding of Slc25a4 1 0.04 0.75 0.1
89 INT120767 Negative_regulation of Gene_expression of GSTP1 3 0.42 1.15 0.09
90 INT289311 Negative_regulation of Gene_expression of Ahr 1 0.02 1 0.09
91 INT134198 Positive_regulation of Binding of AHR 1 0.40 0.07 0.09
92 INT157871 Negative_regulation of Gene_expression of Fth1 1 0.11 0.08 0.08
93 INT120771 Negative_regulation of Positive_regulation of GSTP1 1 0.30 0.39 0.08
94 INT339153 Negative_regulation of Localization of AHR 1 0.06 1.09 0.08
95 INT120766 Regulation of Positive_regulation of GSTP1 1 0.32 0.39 0.08
96 INT195858 Transcription of Ahr 2 0.69 1.33 0.07
97 INT195859 Positive_regulation of Transcription of Ahr 2 0.48 0.73 0.07
98 INT199780 Positive_regulation of Localization of Ahr 2 0.45 1.03 0.07
99 INT197288 Regulation of Positive_regulation of Ahr 1 0.59 0.45 0.07
100 INT278173 Transcription of GSTP1 1 0.68 0.93 0.07
101 INT157874 Gene_expression of Fth1 1 0.16 0.07 0.07
102 INT340266 Negative_regulation of Binding of Ahr 1 0.16 1.33 0.06
103 INT308300 Positive_regulation of Localization of CD34 3 0.44 1.82 0.05
104 INT229654 Positive_regulation of Gene_expression of Cd34 2 0.45 1.19 0.05
105 INT294584 Negative_regulation of Negative_regulation of Ahr 1 0.38 0.56 0.04
106 INT221855 Regulation of Positive_regulation of CD34 1 0.31 0.83 0.04
107 INT222594 Binding of Ucn 1 0.06 0 0.03
108 INT203874 Positive_regulation of Gene_expression of GSTP1 3 0.49 1.91 0
109 INT177821 Negative_regulation of Gene_expression of AHR 1 0.30 0.54 0
110 INT305470 Regulation of Gene_expression of GSTP1 1 0.06 0.59 0
111 INT203877 Phosphorylation of GSTP1 1 0.79 0.22 0
112 INT199764 Positive_regulation of Gene_expression of Gstp1 1 0.55 2.21 0
113 INT320552 Transcription of CD34 1 0.67 1.23 0
114 INT203870 Negative_regulation of Binding of GSTP1 1 0.42 0.22 0
115 INT211502 Negative_regulation of Negative_regulation of AHR 1 0.15 0 0
116 INT308295 Positive_regulation of Positive_regulation of CD34 1 0.60 0.44 0
117 INT290241 Positive_regulation of Gene_expression of SLC25A4 1 0.45 1.54 0
118 INT187311 Regulation of Positive_regulation of AHR 1 0.28 0 0
119 INT294258 Phosphorylation of CD34 1 0.69 0.06 0
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