GO:0060555

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Name induction of necroptosis by extracellular signals
Categary Process
Go Slim No
Go Link GO:0060555
Unique Molecular Interactions 1097
Total Molecular Interactions 1504
Total Single Events 16137
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for induction of necroptosis by extracellular signals. They are ordered first by their pain relevance and then by number of times they were reported for induction of necroptosis by extracellular signals. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT139706 Tnf Positive_regulation of Ltp 1 0.03 2.61 4.63
2 INT61359 TNF Positive_regulation of NFKB1 11 0.63 6.66 3.89
3 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22
4 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61
5 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58
6 INT151826 Tnf Positive_regulation of TNF 1 0.04 3.38 2.51
7 INT117532 SETBP1 Positive_regulation of Gene_expression of TNF 1 0.54 0.85 2.44
8 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41
9 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
10 INT139705 Negative_regulation of Tnf Positive_regulation of Ltp 1 0.03 1.19 2.3
11 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19
12 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
13 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
14 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
15 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09
16 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08
17 INT140032 Tnf Positive_regulation of Gene_expression of Ifng 2 0.43 2.23 2
18 INT140026 Il1b Positive_regulation of Gene_expression of Tnf 2 0.49 2.23 2
19 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95
20 INT129212 RYBP Positive_regulation of Tnf 2 0.03 1.9 1.95
21 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91
22 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8
23 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
24 INT137207 Tnf Positive_regulation of Nfkb1 3 0.23 2.69 1.71
25 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7
26 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
27 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
28 INT167202 TNF Regulation of Gene_expression of Ngf 1 0.10 1.47 1.6
29 INT209853 TNF Regulation of Gene_expression of CD36 1 0.61 3.41 1.59
30 INT266767 SFTPA1 Positive_regulation of Gene_expression of TNF 1 0.01 1.69 1.59
31 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55
32 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54
33 INT167201 Gtf3a Regulation of TNF 1 0.01 1.39 1.52
34 INT158775 Regulation of Tnf Regulation of Ephb1 1 0.18 0.09 1.52
35 INT158777 Tnf Regulation of Ephb1 1 0.18 0.09 1.51
36 INT140029 Ifng Positive_regulation of Gene_expression of Tnf 1 0.43 1.69 1.5
37 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46
38 INT72755 Tap1 Negative_regulation of TNF 1 0.43 2.45 1.46
39 INT131156 Binding of RUNX1 and TNF 2 0.03 3.44 1.42
40 INT161513 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Tnf 1 0.33 0.27 1.35
41 INT160588 TNF Positive_regulation of Gene_expression of OPRM1 1 0.20 0.54 1.35
42 INT56087 TNF Regulation of Gene_expression of SERPINE1 1 0.43 1.67 1.33
43 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29
44 INT130333 FUT3 Negative_regulation of Positive_regulation of Tnf 1 0.01 0.36 1.29
45 INT70037 TNF Regulation of IL10 2 0.09 2.11 1.26
46 INT296796 Tbrs1 Positive_regulation of Gene_expression of TNF 1 0.00 1.58 1.26
47 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
48 INT131807 Bpifa2 Positive_regulation of Localization of Tnf 1 0.32 2.09 1.22
49 INT70035 TNF Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
50 INT70032 TNF Regulation of PRF1 1 0.05 1.42 1.21
51 INT70040 TNF Regulation of Negative_regulation of IL10 1 0.09 1.42 1.21
52 INT328743 TNF Positive_regulation of Mapk14 1 0.04 1.4 1.21
53 INT194619 Il15 Positive_regulation of Gene_expression of TNF 1 0.24 2.23 1.2
54 INT133046 TNF Positive_regulation of Positive_regulation of NFKB1 5 0.54 3.23 1.19
55 INT113242 TNF Regulation of Transcription of OPRM1 2 0.45 1.53 1.19
56 INT314196 Ngf Positive_regulation of Tnf 1 0.50 1.98 1.18
57 INT231769 TNF Negative_regulation of Gene_expression of HMOX1 1 0.26 4.75 1.15
58 INT72754 Adamts7 Negative_regulation of TNF 1 0.28 1.64 1.13
59 INT89938 Tlr4 Positive_regulation of Gene_expression of TNF 6 0.25 1.3 1.12
60 INT107264 Binding of TNF and NCR3 1 0.30 1.42 1.1
61 INT139704 Tnf Positive_regulation of Mapk14 1 0.22 0.73 1.1
62 INT107266 Binding of HLA-DRB1 and TNF 1 0.29 1.41 1.1
63 INT267597 IL10 Negative_regulation of Gene_expression of TNF 1 0.03 2.24 1.1
64 INT107267 Binding of HLA-A and TNF 1 0.34 1.41 1.1
65 INT94495 Tnf Positive_regulation of Gene_expression of Il6 1 0.30 1.9 1.09
66 INT151825 Tnf Positive_regulation of Mapk14 1 0.22 1.72 1.09
67 INT94500 Tnf Positive_regulation of Gene_expression of Il1b 1 0.25 1.9 1.09
68 INT139703 Tnf Positive_regulation of Mapk8 1 0.32 0.73 1.08
69 INT152502 Tnf Negative_regulation of Binding of Tnfrsf1a 1 0.37 0.6 1.08
70 INT119108 Binding of LTBR and TNF 2 0.15 1.47 1.07
71 INT114364 Hmgb1 Positive_regulation of Gene_expression of TNF 2 0.05 1.85 1.06
72 INT120312 Ghrh Regulation of Tnf 1 0.26 0.95 1.05
73 INT120314 Ghrh Regulation of Positive_regulation of Tnf 1 0.43 0.95 1.05
74 INT152504 Binding of CR1 and Tnf 1 0.00 0.49 1.04
75 INT133650 Epo Negative_regulation of TNF 1 0.35 2.7 1.04
76 INT156245 NFKB1 Positive_regulation of Regulation of TNF 1 0.45 0.76 1.03
77 INT81545 Tnf Positive_regulation of Gtf3a 2 0.03 1.41 1.02
78 INT91813 Binding of FAS and FASLG 4 0.23 9.89 0.99
79 INT308804 Pld1 Positive_regulation of TNF 1 0.05 2.42 0.99
80 INT274895 Positive_regulation of Cbr2 Negative_regulation of Gene_expression of TNF 1 0.06 1.21 0.99
81 INT129216 Negative_regulation of RYBP Positive_regulation of Tnf 1 0.01 1.24 0.98
82 INT182022 TNF Positive_regulation of Gene_expression of Tnfrsf11b 1 0.06 1.56 0.98
83 INT209852 TNF Negative_regulation of Gene_expression of CD36 1 0.43 0.61 0.98
84 INT154255 Tnf Positive_regulation of IL1B 1 0.54 0.94 0.97
85 INT154254 Tnf Positive_regulation of Il6 1 0.36 0.94 0.97
86 INT114320 TNF Positive_regulation of Gene_expression of Il6 1 0.07 1.73 0.97
87 INT103133 TNF Positive_regulation of Gene_expression of IL8 2 0.48 1.26 0.96
88 INT133652 Epo Negative_regulation of Gene_expression of TNF 1 0.35 2.64 0.96
89 INT171264 TNF Positive_regulation of MMP1 2 0.10 2.05 0.95
90 INT188805 TNF Positive_regulation of Gene_expression of Crp 1 0.15 2.96 0.95
91 INT100018 TNF Positive_regulation of MAPK1 3 0.24 1.56 0.94
92 INT133050 TNF Positive_regulation of Gene_expression of ICAM1 3 0.67 1.91 0.94
93 INT182024 TNF Positive_regulation of Gene_expression of Il6 1 0.05 1.58 0.94
94 INT129211 RYBP Positive_regulation of Gene_expression of Tnf 1 0.01 1.04 0.94
95 INT155259 RUNX1 Negative_regulation of Tnf 1 0.00 1.48 0.93
96 INT165280 Tnf Positive_regulation of Gene_expression of Nos2 1 0.24 1.02 0.91
97 INT254242 TNF Positive_regulation of Gene_expression of DKK1 1 0.14 1.24 0.91
98 INT256646 Tnf Positive_regulation of Positive_regulation of Nfkb1 1 0.22 1.83 0.9
99 INT222988 TNF Positive_regulation of Protein_catabolism of COL1A1 1 0.01 1.66 0.9
100 INT211128 Binding of P4HB and TNF 1 0.09 0.97 0.9
101 INT211129 Negative_regulation of Binding of P4HB and TNF 1 0.10 0.97 0.9
102 INT120147 Tlr4 Positive_regulation of Tnf 3 0.39 2.14 0.89
103 INT80132 Binding of HLA-B and TNF 1 0.04 1.15 0.89
104 INT142278 Slc8a1 Regulation of Tnf 1 0.14 0.07 0.89
105 INT167466 Ccdc80 Negative_regulation of Tnf 1 0.01 0.76 0.88
106 INT134311 Tnf Positive_regulation of Protein_catabolism of Nfkbia 1 0.18 0.57 0.88
107 INT116556 Olr1627 Negative_regulation of Regulation of Tnf 1 0.01 1.52 0.87
108 INT97795 IRF6 Positive_regulation of Localization of TNF 3 0.09 1.57 0.86
109 INT152868 Tnf Regulation of Gene_expression of Trpv1 1 0.27 0.25 0.86
110 INT130769 FASLG Negative_regulation of Binding of FAS 1 0.10 0.66 0.86
111 INT110315 Negative_regulation of ALOX5 Negative_regulation of Gene_expression of TNF 1 0.47 0.74 0.85
112 INT215598 Positive_regulation of P2rx7 Positive_regulation of Localization of TNF 1 0.22 1.44 0.85
113 INT196638 TNF Positive_regulation of F2RL1 2 0.09 1.52 0.84
114 INT146919 Tnf Positive_regulation of Gene_expression of Ccl2 1 0.16 1.44 0.84
115 INT238641 Binding of TNF and Ifx 1 0.07 0.86 0.84
116 INT238642 Binding of TNF and Ada 1 0.03 0.86 0.84
117 INT105435 TNF Positive_regulation of IL6 5 0.25 4.45 0.83
118 INT149626 Il1b Regulation of Gene_expression of Tnf 1 0.41 0.83 0.83
119 INT102201 Tnf Regulation of Il1b 3 0.39 2.57 0.82
120 INT162071 Gene_expression of MC1R Negative_regulation of Gene_expression of TNF 1 0.41 0.34 0.82
121 INT66206 Negative_regulation of TNF Positive_regulation of NFKB1 2 0.53 1.71 0.81
122 INT126555 Binding of Ighg1 and Tnf 1 0.35 2.2 0.8
123 INT147755 Binding of GNRH1 and TNF 1 0.32 2.37 0.79
124 INT110518 Tnf Positive_regulation of Prkce 1 0.26 1.43 0.78
125 INT188531 Binding of TNF and PDXK 1 0.03 1.99 0.78
126 INT102163 Binding of TNF and Mmp9 1 0.12 0.88 0.78
127 INT306259 HDAC9 Negative_regulation of Gene_expression of TNF 1 0.21 0.89 0.78
128 INT102161 Binding of TNF and Mmp2 1 0.10 0.88 0.78
129 INT306258 HDAC4 Negative_regulation of Gene_expression of TNF 1 0.09 0.89 0.78
130 INT130138 TNF Negative_regulation of Gene_expression of S100A10 1 0.06 1.32 0.78
131 INT102162 Binding of TNF and Adam17 1 0.14 0.88 0.78
132 INT296797 Tlr9 Regulation of Positive_regulation of TNF 1 0.03 1.37 0.77
133 INT296798 Gopc Regulation of Positive_regulation of TNF 1 0.01 1.37 0.77
134 INT152869 Tnf Positive_regulation of Gene_expression of Trpv1 1 0.46 0.48 0.77
135 INT209883 TNF Positive_regulation of Gene_expression of TNFRSF11A 1 0.20 1.83 0.77
136 INT194644 Tlr4 Positive_regulation of TNF 6 0.58 2.42 0.76
137 INT149192 TNF Positive_regulation of Gene_expression of VCAM1 3 0.57 1.4 0.76
138 INT26497 TNF Positive_regulation of Gene_expression of MMP2 1 0.44 1.5 0.75
139 INT113472 TNF Positive_regulation of Localization of MMP14 1 0.47 0.45 0.75
140 INT308176 TNF Regulation of Tnfrsf1a 1 0.05 1.19 0.75
141 INT354455 Il11 Negative_regulation of Gene_expression of Tnf 1 0.31 1.21 0.74
142 INT301141 Nsa2 Positive_regulation of TNF 1 0.01 0.6 0.74
143 INT301142 Negative_regulation of Nsa2 Positive_regulation of TNF 1 0.01 0.6 0.74
144 INT4875 TNF Regulation of MME 1 0.51 0.71 0.74
145 INT86657 TNF Regulation of H2-Ab1 1 0.02 0.84 0.74
146 INT190174 TNF Positive_regulation of MMP12 1 0.27 0.08 0.74
147 INT96301 Olr1742 Negative_regulation of Gene_expression of Tnf 1 0.14 0 0.74
148 INT211127 Regulation of Binding of MTX1 and TNF 1 0.22 0.71 0.74
149 INT211130 Binding of MTX1 and TNF 1 0.18 0.7 0.73
150 INT228499 Binding of FAS and Fasl 1 0.15 2.75 0.73
151 INT172147 Binding of IL15 and TNF 2 0.05 1.19 0.72
152 INT150992 Sfpq Negative_regulation of Gene_expression of Tnf 1 0.03 0.69 0.72
153 INT51006 PDYN Positive_regulation of TNF 1 0.11 0.84 0.72
154 INT117535 SND1 Positive_regulation of Gene_expression of TNF 1 0.06 0.29 0.71
155 INT113499 TNF Positive_regulation of Gene_expression of BHLHE23 1 0.25 0.1 0.71
156 INT159963 Tnf Positive_regulation of Localization of Il6 1 0.12 2.32 0.71
157 INT187115 Binding of TIMP1 and TNF 2 0.30 1.07 0.7
158 INT171901 Binding of TNF and Il1 2 0.18 1.07 0.7
159 INT117534 TNF Positive_regulation of Positive_regulation of SND1 1 0.06 0.29 0.7
160 INT117533 TNF Positive_regulation of Positive_regulation of SETBP1 1 0.34 0.29 0.7
161 INT83628 TNF Positive_regulation of Gene_expression of Cd59 1 0.06 1.09 0.7
162 INT172143 IL4 Positive_regulation of Protein_catabolism of TNF 2 0.11 1.7 0.69
163 INT172146 IL10 Positive_regulation of Protein_catabolism of TNF 2 0.15 1.69 0.69
164 INT83625 Tnf Positive_regulation of Gene_expression of Cd59 1 0.15 1.08 0.69
165 INT334395 IL1B Positive_regulation of Tnf 1 0.11 2.83 0.69
166 INT113959 TNF Positive_regulation of Gene_expression of IK 1 0.02 0.66 0.69
167 INT190527 TNF Positive_regulation of Gene_expression of Ros1 1 0.01 1.02 0.68
168 INT119107 Negative_regulation of Binding of LTBR and TNF 1 0.17 1.16 0.68
169 INT203758 Binding of IL6 and TNF 3 0.26 2.03 0.67
170 INT231349 Il10 Negative_regulation of Gene_expression of TNF 2 0.23 1.82 0.67
171 INT119105 Binding of FCGR1A and TNF 1 0.03 1.16 0.67
172 INT119106 Negative_regulation of Binding of FCGR1A and TNF 1 0.03 1.16 0.67
173 INT264338 Binding of IL-17 and Positive_regulation of Localization of TNF 1 0.04 1.71 0.67
174 INT314199 Mapk14 Regulation of Tnf 1 0.26 0.71 0.67
175 INT148139 Phosphorylation of Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.46 0.98 0.66
176 INT137142 Binding of ITIH4 and Positive_regulation of Localization of TNF 1 0.40 0.71 0.66
177 INT148138 Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.64 0.98 0.66
178 INT252293 Binding of TNF and Positive_regulation of Gene_expression of Ccl20 1 0.04 0.54 0.66
179 INT120144 Negative_regulation of Tlr4 Positive_regulation of Tnf 1 0.18 0.91 0.66
180 INT120146 seb Positive_regulation of Gene_expression of Tnf 1 0.40 0.86 0.66
181 INT120145 seb Positive_regulation of Tnf 1 0.40 0.85 0.65
182 INT254230 Ik Negative_regulation of Gene_expression of TNF 1 0.00 1.29 0.65
183 INT132689 Tnf Regulation of Dnajc13 1 0.01 1.27 0.65
184 INT295705 Binding of IK and TNF 1 0.00 0.27 0.64
185 INT292893 TNF Regulation of IL8 2 0.27 1.3 0.63
186 INT165047 Mapk14 Positive_regulation of Gene_expression of Tnf 1 0.73 0.8 0.63
187 INT176476 TNF Positive_regulation of Gene_expression of SELE 1 0.04 0.57 0.63
188 INT220117 Il6 Positive_regulation of TNF 1 0.01 2.45 0.63
189 INT165048 Trib3 Positive_regulation of Gene_expression of Tnf 1 0.08 0.8 0.63
190 INT148137 Tnf Positive_regulation of Positive_regulation of Mapk14 1 0.46 1 0.63
191 INT100030 TNF Positive_regulation of Mapk8 1 0.12 1.57 0.63
192 INT120851 NFKB1 Positive_regulation of Localization of TNF 3 0.04 2.05 0.62
193 INT60328 Il1b Positive_regulation of Tnf 2 0.29 1.84 0.62
194 INT9163 Tnf Regulation of Gene_expression of Glul 1 0.12 1.99 0.62
195 INT230595 Binding of TNF and Tecr 1 0.03 1 0.62
196 INT172048 Binding of TNF and MICA 1 0.29 1.63 0.62
197 INT61826 Tnf Negative_regulation of Il1b 1 0.39 0.89 0.62
198 INT66207 Positive_regulation of TNF Positive_regulation of NFKB1 1 0.42 0.08 0.61
199 INT158362 Tnf Positive_regulation of Steap4 1 0.55 1.6 0.61
200 INT293704 Binding of TNF and DDX41 1 0.00 1.01 0.61

Single Events

The table below shows the top 100 pain related interactions that have been reported for induction of necroptosis by extracellular signals. They are ordered first by their pain relevance and then by number of times they were reported in induction of necroptosis by extracellular signals. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82
2 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98
3 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81
4 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68
5 INT6852 Localization of TNF 883 0.81 705.95 270.84
6 INT6481 Binding of TNF 624 0.48 510.2 214.82
7 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210
8 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58
9 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1
10 INT9660 Regulation of TNF 363 0.62 312.94 139.99
11 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61
12 INT10166 Localization of Tnf 237 0.81 153.95 88.64
13 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99
14 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71
15 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54
16 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85
17 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05
18 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47
19 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18
20 INT66029 Negative_regulation of Tnf 100 0.59 84.28 48.16
21 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33
22 INT5307 Regulation of Tnf 87 0.62 78.71 43.4
23 INT13354 Transcription of TNF 108 0.72 85.81 42.32
24 INT53577 Negative_regulation of Localization of TNF 110 0.59 59.28 35.23
25 INT35406 Localization of Tnf 94 0.81 64.63 31.65
26 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59
27 INT93626 Gene_expression of Fasl 118 0.75 115.24 25.11
28 INT66753 Negative_regulation of Positive_regulation of Tnf 45 0.59 35.28 22.33
29 INT8483 Positive_regulation of Positive_regulation of TNF 73 0.67 60.35 22.03
30 INT53575 Regulation of Gene_expression of Tnf 46 0.62 34.35 20.63
31 INT53574 Regulation of Tnf 45 0.62 40.68 19.71
32 INT66751 Negative_regulation of Localization of Tnf 48 0.59 26 19.36
33 INT66755 Transcription of Tnf 45 0.72 37.1 19.11
34 INT10169 Positive_regulation of Localization of Tnf 44 0.70 27.71 16.75
35 INT19929 Negative_regulation of Positive_regulation of TNF 52 0.59 38.16 16.51
36 INT49986 Transcription of Tnf 25 0.72 18.3 16.22
37 INT12087 Regulation of Localization of TNF 44 0.62 28.71 15.17
38 INT10173 Binding of Tnf 45 0.48 35.6 14.32
39 INT64048 Positive_regulation of Positive_regulation of Tnf 32 0.70 21.24 13.74
40 INT6478 Negative_regulation of Binding of TNF 36 0.58 30.42 13.31
41 INT89404 Regulation of Negative_regulation of TNF 30 0.45 24.47 12.71
42 INT93620 Positive_regulation of Gene_expression of Fasl 51 0.66 59.45 12.04
43 INT51265 Phosphorylation of TNF 32 0.81 25.33 10.75
44 INT60434 Negative_regulation of Positive_regulation of Tnf 20 0.46 10.01 10.64
45 INT80110 Regulation of Positive_regulation of TNF 34 0.44 25.79 9.78
46 INT86851 Gene_expression of Faslg 45 0.75 24.42 9.21
47 INT48860 Regulation of Localization of Tnf 25 0.61 20.68 8.78
48 INT53573 Negative_regulation of Localization of Tnf 19 0.59 11.57 8.54
49 INT86411 Negative_regulation of Negative_regulation of TNF 24 0.42 17.6 7.89
50 INT49490 Positive_regulation of Transcription of TNF 19 0.70 14.76 7.58
51 INT95133 Gene_expression of FASLG 38 0.75 44.09 7.51
52 INT68299 Binding of Tnf 17 0.39 12.55 7.49
53 INT66752 Positive_regulation of Transcription of Tnf 15 0.68 10.86 7.26
54 INT99942 Positive_regulation of Fasl 37 0.68 32.61 6.92
55 INT69985 Positive_regulation of Negative_regulation of TNF 21 0.50 13.26 6.31
56 INT172084 Positive_regulation of Binding of TNF 21 0.50 15.31 6.06
57 INT67060 Negative_regulation of Transcription of TNF 17 0.59 12.94 5.88
58 INT6487 Positive_regulation of Positive_regulation of Tnf 21 0.56 16.06 5.64
59 INT58145 Positive_regulation of Localization of Tnf 20 0.67 13.33 5.44
60 INT88019 Positive_regulation of Gene_expression of Faslg 16 0.67 11.31 5.05
61 INT92054 Positive_regulation of Transcription of Tnf 8 0.50 4.93 5.05
62 INT55698 Regulation of Binding of TNF 13 0.44 8.98 4.74
63 INT66754 Negative_regulation of Transcription of Tnf 11 0.43 8.43 3.93
64 INT23088 Phosphorylation of Tnf 15 0.79 9.85 3.82
65 INT172173 Protein_catabolism of TNF 16 0.96 9.95 3.79
66 INT133768 Regulation of Fasl 10 0.44 10.24 3.32
67 INT65427 Regulation of Positive_regulation of Tnf 7 0.60 3.49 3.22
68 INT188406 Binding of Fasl 19 0.44 24.67 3.17
69 INT95049 Negative_regulation of Regulation of Tnf 4 0.42 1.64 2.84
70 INT75736 Regulation of Localization of Tnf 6 0.62 4.61 2.67
71 INT98607 Regulation of Regulation of TNF 8 0.44 6.95 2.56
72 INT107302 Negative_regulation of Gene_expression of Fasl 7 0.42 8.52 2.54
73 INT95136 Binding of FASLG 6 0.33 8.01 2.41
74 INT137960 Positive_regulation of FASLG 8 0.67 6.5 2.34
75 INT133766 Negative_regulation of Fasl 11 0.56 11.28 2.27
76 INT93395 Transcription of Faslg 6 0.51 5.64 2.26
77 INT66804 Negative_regulation of Negative_regulation of Tnf 4 0.56 2.79 2.26
78 INT114898 Regulation of Transcription of TNF 4 0.35 2.69 2.18
79 INT122649 Positive_regulation of Regulation of Tnf 2 0.49 2.78 1.96
80 INT88016 Negative_regulation of Gene_expression of Faslg 5 0.54 2.18 1.93
81 INT102147 Negative_regulation of Faslg 5 0.19 4.56 1.92
82 INT130775 Regulation of FASLG 4 0.30 5.8 1.82
83 INT77801 Negative_regulation of Binding of Tnf 5 0.42 3.93 1.77
84 INT159957 Positive_regulation of Phosphorylation of Tnf 3 0.49 2.63 1.65
85 INT107299 Transcription of Fasl 6 0.68 5 1.64
86 INT93394 Positive_regulation of Transcription of Faslg 1 0.24 3.57 1.57
87 INT161379 Localization of Fasl 8 0.67 11.05 1.56
88 INT183791 Positive_regulation of Phosphorylation of TNF 6 0.49 4.72 1.56
89 INT137819 Binding of Faslg 3 0.09 1.78 1.51
90 INT61967 Positive_regulation of Negative_regulation of Tnf 3 0.50 2.46 1.49
91 INT88015 Positive_regulation of Faslg 5 0.65 5.73 1.44
92 INT83659 Negative_regulation of Binding of Tnf 3 0.37 1.57 1.42
93 INT135551 Positive_regulation of Gene_expression of FASLG 2 0.67 6.71 1.26
94 INT135803 Regulation of Gene_expression of Fasl 6 0.36 4.35 1.24
95 INT130774 Transcription of FASLG 5 0.67 2.02 1.22
96 INT124317 Regulation of Gene_expression of FASLG 2 0.23 1.54 1.1
97 INT129587 Protein_catabolism of Tnf 2 0.86 1.41 1.08
98 INT188407 Positive_regulation of Binding of Fasl 1 0.48 3.67 1.08
99 INT168276 Negative_regulation of Phosphorylation of Tnf 1 0.19 1.3 1.08
100 INT135027 Regulation of Positive_regulation of Tnf 3 0.38 2.84 1.05
101 INT99941 Negative_regulation of Positive_regulation of Fasl 3 0.44 2.24 0.93
102 INT134307 Negative_regulation of Protein_catabolism of Tnf 1 0.41 0.57 0.88
103 INT115822 Regulation of Transcription of Tnf 3 0.35 1.96 0.87
104 INT130770 Positive_regulation of Transcription of FASLG 1 0.22 0.68 0.87
105 INT134310 Positive_regulation of Protein_catabolism of Tnf 1 0.49 0.57 0.87
106 INT86852 Regulation of Faslg 3 0.42 1.67 0.79
107 INT136690 Regulation of Negative_regulation of Tnf 5 0.45 3.58 0.78
108 INT102199 Regulation of Transcription of Tnf 2 0.45 2.25 0.78
109 INT237158 Negative_regulation of Negative_regulation of Tnf 2 0.13 1.37 0.74
110 INT33317 Negative_regulation of RIPK1 1 0.31 0.05 0.67
111 INT95135 Negative_regulation of Gene_expression of FASLG 4 0.20 2.99 0.64
112 INT354814 Positive_regulation of Localization of Fasl 3 0.29 3.61 0.64
113 INT51263 Regulation of Phosphorylation of TNF 2 0.26 1.06 0.63
114 INT235079 Negative_regulation of Phosphorylation of TNF 2 0.41 1.16 0.6
115 INT188405 Positive_regulation of Positive_regulation of Fasl 4 0.64 3.54 0.48
116 INT141194 Regulation of Negative_regulation of Tnf 3 0.42 1.57 0.47
117 INT161266 Positive_regulation of Ripk1 1 0.49 0.09 0.47
118 INT323752 Negative_regulation of FASLG 2 0.18 2.36 0.43
119 INT138003 Positive_regulation of Negative_regulation of Tnf 2 0.49 2.07 0.43
120 INT72086 Regulation of Regulation of Tnf 1 0.45 0.3 0.4
121 INT88021 Regulation of Gene_expression of Faslg 4 0.60 2.6 0.38
122 INT95132 Negative_regulation of Binding of FASLG 1 0.18 0.63 0.38
123 INT159782 Phosphorylation of Tnf 2 0.79 1.51 0.36
124 INT143535 Protein_catabolism of Tnf 2 0.86 3.43 0.33
125 INT116034 Negative_regulation of Transcription of Tnf 2 0.41 0.17 0.29
126 INT135805 Positive_regulation of Negative_regulation of Fasl 1 0.48 0.24 0.27
127 INT88018 Positive_regulation of Positive_regulation of Faslg 1 0.47 0.75 0.23
128 INT302807 Gene_expression of Ripk1 1 0.04 0.93 0.23
129 INT194643 Positive_regulation of Regulation of TNF 2 0.28 2.4 0.21
130 INT94547 Localization of Faslg 1 0.76 0.71 0.21
131 INT81351 Negative_regulation of Regulation of TNF 1 0.33 0.23 0.21
132 INT355529 Negative_regulation of Transcription of Fasl 1 0.26 1.23 0.2
133 INT159783 Positive_regulation of Phosphorylation of Tnf 1 0.12 0.39 0.19
134 INT240602 Gene_expression of RIPK1 2 0.58 0.69 0.16
135 INT251578 Positive_regulation of Protein_catabolism of TNF 1 0.41 0.26 0.16
136 INT347940 Regulation of Positive_regulation of Fasl 1 0.30 1.95 0.13
137 INT170142 Regulation of Protein_catabolism of Tnf 1 0.44 1.53 0.13
138 INT295324 Regulation of Binding of Tnf 2 0.44 1.11 0.09
139 INT274227 Negative_regulation of Binding of Fasl 2 0.37 1.96 0.08
140 INT250476 Negative_regulation of Transcription of FASLG 1 0.22 0.76 0.06
141 INT354783 Positive_regulation of Regulation of Fasl 1 0.20 1.49 0.05
142 INT251555 Binding of Ripk1 1 0.17 1.16 0.04
143 INT159591 Positive_regulation of Binding of Tnf 1 0.43 0.06 0
144 INT210195 Regulation of Transcription of FASLG 1 0.08 0 0
145 INT292589 Positive_regulation of Localization of RIPK1 1 0.15 0 0
146 INT292578 Positive_regulation of RIPK1 1 0.07 0 0
147 INT351934 Regulation of Binding of Fasl 1 0.36 1.83 0
148 INT299546 Negative_regulation of Gene_expression of RIPK1 1 0.02 0.06 0
149 INT252760 Binding of RIPK1 1 0.19 0.77 0
150 INT292592 Regulation of Localization of RIPK1 1 0.13 0 0
151 INT101130 Protein_catabolism of Fasl 1 0.42 0.29 0
152 INT292593 Localization of RIPK1 1 0.22 0 0
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