GO:0060559

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Name positive regulation of calcidiol 1-monooxygenase activity
Categary Process
Go Slim No
Go Link GO:0060559
Unique Molecular Interactions 1750
Total Molecular Interactions 2431
Total Single Events 22102
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of calcidiol 1-monooxygenase activity. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of calcidiol 1-monooxygenase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
2 INT139706 Tnf Positive_regulation of Ltp 1 0.03 2.61 4.63
3 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
4 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
5 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
6 INT61359 TNF Positive_regulation of NFKB1 11 0.63 6.66 3.89
7 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
8 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22
9 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
10 INT150886 Il1a Regulation of Il1b 1 0.02 3.46 2.93
11 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85
12 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61
13 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58
14 INT151826 Tnf Positive_regulation of TNF 1 0.04 3.38 2.51
15 INT117532 SETBP1 Positive_regulation of Gene_expression of TNF 1 0.54 0.85 2.44
16 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41
17 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
18 INT139705 Negative_regulation of Tnf Positive_regulation of Ltp 1 0.03 1.19 2.3
19 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19
20 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19
21 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
22 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
23 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19
24 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
25 INT209924 IL1B Negative_regulation of PPARA 1 0.20 4.38 2.17
26 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09
27 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08
28 INT81295 Ifng Positive_regulation of Gene_expression of Nos2 4 0.39 0.87 2.05
29 INT140032 Tnf Positive_regulation of Gene_expression of Ifng 2 0.43 2.23 2
30 INT140030 Il1b Positive_regulation of Gene_expression of Ifng 2 0.48 2.23 2
31 INT140026 Il1b Positive_regulation of Gene_expression of Tnf 2 0.49 2.23 2
32 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95
33 INT129212 RYBP Positive_regulation of Tnf 2 0.03 1.9 1.95
34 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91
35 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
36 INT81920 Binding of IL1B and NFKB1 1 0.04 1.54 1.85
37 INT50993 Il1b Positive_regulation of Fos 2 0.40 0.43 1.84
38 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8
39 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
40 INT137207 Tnf Positive_regulation of Nfkb1 3 0.23 2.69 1.71
41 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7
42 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
43 INT100274 IL1RN Negative_regulation of IL1B 5 0.53 1.79 1.65
44 INT83093 IL1B Positive_regulation of BDKRB1 1 0.51 0.44 1.65
45 INT61134 IL10 Negative_regulation of Gene_expression of IL1B 3 0.46 2.13 1.63
46 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
47 INT167202 TNF Regulation of Gene_expression of Ngf 1 0.10 1.47 1.6
48 INT209853 TNF Regulation of Gene_expression of CD36 1 0.61 3.41 1.59
49 INT266767 SFTPA1 Positive_regulation of Gene_expression of TNF 1 0.01 1.69 1.59
50 INT74937 IL1B Positive_regulation of CPOX 5 0.18 1.13 1.55
51 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55
52 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54
53 INT91456 IL1B Positive_regulation of Gene_expression of CPOX 6 0.17 3.36 1.53
54 INT167201 Gtf3a Regulation of TNF 1 0.01 1.39 1.52
55 INT158775 Regulation of Tnf Regulation of Ephb1 1 0.18 0.09 1.52
56 INT158777 Tnf Regulation of Ephb1 1 0.18 0.09 1.51
57 INT10276 Il1b Regulation of Gene_expression of Penk 1 0.61 0.85 1.5
58 INT140029 Ifng Positive_regulation of Gene_expression of Tnf 1 0.43 1.69 1.5
59 INT140028 Ifng Positive_regulation of Gene_expression of Il1b 1 0.48 1.69 1.5
60 INT92057 Ifng Positive_regulation of Gene_expression of Ik 1 0.03 0.45 1.49
61 INT150887 Il1b Regulation of Il10 1 0.04 1.74 1.47
62 INT158776 Il1b Regulation of Ephb1 1 0.15 0.09 1.46
63 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46
64 INT72755 Tap1 Negative_regulation of TNF 1 0.43 2.45 1.46
65 INT131156 Binding of RUNX1 and TNF 2 0.03 3.44 1.42
66 INT83626 Ifng Positive_regulation of Gene_expression of Cd59 1 0.33 2.19 1.41
67 INT197111 Binding of IL1B and MCF2 1 0.02 2.12 1.4
68 INT161511 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il1b 1 0.41 0.27 1.36
69 INT161513 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Tnf 1 0.33 0.27 1.35
70 INT160588 TNF Positive_regulation of Gene_expression of OPRM1 1 0.20 0.54 1.35
71 INT160587 IFNG Positive_regulation of Gene_expression of OPRM1 1 0.18 0.54 1.35
72 INT56087 TNF Regulation of Gene_expression of SERPINE1 1 0.43 1.67 1.33
73 INT95093 ITIH4 Positive_regulation of IL1B 1 0.43 1.04 1.32
74 INT95094 Negative_regulation of ITIH4 Positive_regulation of IL1B 1 0.36 1.04 1.32
75 INT121705 IL1B Positive_regulation of Gene_expression of MMP3 3 0.49 1.2 1.3
76 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29
77 INT130333 FUT3 Negative_regulation of Positive_regulation of Tnf 1 0.01 0.36 1.29
78 INT108386 IL1B Positive_regulation of MMP1 3 0.27 1.56 1.28
79 INT121703 IL1B Positive_regulation of Gene_expression of MMP1 3 0.49 1.14 1.27
80 INT34052 POMC Regulation of Gene_expression of IFNG 1 0.11 0 1.27
81 INT70037 TNF Regulation of IL10 2 0.09 2.11 1.26
82 INT296796 Tbrs1 Positive_regulation of Gene_expression of TNF 1 0.00 1.58 1.26
83 INT161507 Tlr4 Positive_regulation of Gene_expression of Il1b 1 0.24 0.19 1.25
84 INT108389 IL1B Positive_regulation of ADAMTS4 1 0.51 1.19 1.24
85 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
86 INT131807 Bpifa2 Positive_regulation of Localization of Tnf 1 0.32 2.09 1.22
87 INT70035 TNF Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
88 INT70039 IL1B Regulation of Negative_regulation of IL10 1 0.07 1.42 1.21
89 INT70032 TNF Regulation of PRF1 1 0.05 1.42 1.21
90 INT70040 TNF Regulation of Negative_regulation of IL10 1 0.09 1.42 1.21
91 INT70038 IL1B Regulation of PRF1 1 0.05 1.42 1.21
92 INT328743 TNF Positive_regulation of Mapk14 1 0.04 1.4 1.21
93 INT70031 IL1B Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
94 INT70030 IL1B Regulation of IL10 1 0.07 1.42 1.21
95 INT194861 Binding of IL1B and IL1R1 2 0.01 1.55 1.2
96 INT209926 IL1B Regulation of PPARA 1 0.21 2.45 1.2
97 INT194619 Il15 Positive_regulation of Gene_expression of TNF 1 0.24 2.23 1.2
98 INT133046 TNF Positive_regulation of Positive_regulation of NFKB1 5 0.54 3.23 1.19
99 INT113242 TNF Regulation of Transcription of OPRM1 2 0.45 1.53 1.19
100 INT314196 Ngf Positive_regulation of Tnf 1 0.50 1.98 1.18
101 INT289465 IRF6 Positive_regulation of IL1B 3 0.05 0.9 1.16
102 INT94502 Il1b Positive_regulation of Gene_expression of Avp 1 0.28 1.97 1.15
103 INT94509 Il1b Positive_regulation of Gene_expression of AVP 1 0.36 1.96 1.15
104 INT231769 TNF Negative_regulation of Gene_expression of HMOX1 1 0.26 4.75 1.15
105 INT66767 Il1b Positive_regulation of Pla2g10 1 0.05 0.47 1.13
106 INT94498 Il1b Positive_regulation of Gene_expression of Crh 1 0.24 1.94 1.13
107 INT141979 Calca Negative_regulation of Gene_expression of Il1b 1 0.40 0.62 1.13
108 INT72754 Adamts7 Negative_regulation of TNF 1 0.28 1.64 1.13
109 INT89938 Tlr4 Positive_regulation of Gene_expression of TNF 6 0.25 1.3 1.12
110 INT66907 Il1b Positive_regulation of Localization of Oxt 2 0.78 0.18 1.12
111 INT167428 Il1b Positive_regulation of Localization of Gpt 1 0.43 1.31 1.11
112 INT107264 Binding of TNF and NCR3 1 0.30 1.42 1.1
113 INT139704 Tnf Positive_regulation of Mapk14 1 0.22 0.73 1.1
114 INT107266 Binding of HLA-DRB1 and TNF 1 0.29 1.41 1.1
115 INT122889 Ifng Positive_regulation of Gene_expression of HLA-E 1 0.02 0.97 1.1
116 INT267597 IL10 Negative_regulation of Gene_expression of TNF 1 0.03 2.24 1.1
117 INT107267 Binding of HLA-A and TNF 1 0.34 1.41 1.1
118 INT57982 Il1b Positive_regulation of Crh 2 0.38 0.98 1.09
119 INT94495 Tnf Positive_regulation of Gene_expression of Il6 1 0.30 1.9 1.09
120 INT107562 Penk Positive_regulation of Localization of Il1b 1 0.20 0.09 1.09
121 INT107561 Mtr Positive_regulation of Localization of Il1b 1 0.04 0.09 1.09
122 INT74939 IL1B Positive_regulation of Gene_expression of HGF 1 0.58 0.72 1.09
123 INT151825 Tnf Positive_regulation of Mapk14 1 0.22 1.72 1.09
124 INT94500 Tnf Positive_regulation of Gene_expression of Il1b 1 0.25 1.9 1.09
125 INT76396 Il10 Negative_regulation of Il1b 2 0.65 1.89 1.08
126 INT107567 Hps4 Positive_regulation of Localization of Il1b 1 0.01 0.09 1.08
127 INT139703 Tnf Positive_regulation of Mapk8 1 0.32 0.73 1.08
128 INT152502 Tnf Negative_regulation of Binding of Tnfrsf1a 1 0.37 0.6 1.08
129 INT119108 Binding of LTBR and TNF 2 0.15 1.47 1.07
130 INT107564 Hps4 Regulation of Localization of Il1b 1 0.01 0.1 1.07
131 INT107560 Penk Regulation of Localization of Il1b 1 0.18 0.1 1.07
132 INT114364 Hmgb1 Positive_regulation of Gene_expression of TNF 2 0.05 1.85 1.06
133 INT57986 Il1b Regulation of Positive_regulation of Il6 2 0.39 0.23 1.05
134 INT120312 Ghrh Regulation of Tnf 1 0.26 0.95 1.05
135 INT120314 Ghrh Regulation of Positive_regulation of Tnf 1 0.43 0.95 1.05
136 INT152504 Binding of CR1 and Tnf 1 0.00 0.49 1.04
137 INT162319 Positive_regulation of F2rl1 Positive_regulation of Il1b 1 0.46 1.6 1.04
138 INT113235 Tacr1 Regulation of Gene_expression of Ifng 1 0.26 1 1.04
139 INT133650 Epo Negative_regulation of TNF 1 0.35 2.7 1.04
140 INT65986 IL1B Positive_regulation of PTGS2 3 0.32 2.05 1.03
141 INT88875 Ifng Positive_regulation of Transcription of Nos2 1 0.02 0.27 1.03
142 INT128297 Il1b Positive_regulation of CRH 1 0.02 0.27 1.03
143 INT156245 NFKB1 Positive_regulation of Regulation of TNF 1 0.45 0.76 1.03
144 INT81545 Tnf Positive_regulation of Gtf3a 2 0.03 1.41 1.02
145 INT88874 Ifng Regulation of Nos2 1 0.01 0.26 1.01
146 INT271875 IL1RN Negative_regulation of Binding of IL1B 1 0.01 1.3 1.01
147 INT88879 Ifng Positive_regulation of Nfkb1 1 0.01 0.26 1.01
148 INT308804 Pld1 Positive_regulation of TNF 1 0.05 2.42 0.99
149 INT102690 IL1B Positive_regulation of ITGAL 1 0.05 0.87 0.99
150 INT274895 Positive_regulation of Cbr2 Negative_regulation of Gene_expression of TNF 1 0.06 1.21 0.99
151 INT103651 IL1B Positive_regulation of Gene_expression of IL8 6 0.78 1.23 0.98
152 INT103796 IL1B Positive_regulation of Gene_expression of SELE 2 0.08 1 0.98
153 INT129216 Negative_regulation of RYBP Positive_regulation of Tnf 1 0.01 1.24 0.98
154 INT182022 TNF Positive_regulation of Gene_expression of Tnfrsf11b 1 0.06 1.56 0.98
155 INT209852 TNF Negative_regulation of Gene_expression of CD36 1 0.43 0.61 0.98
156 INT94493 Avp Positive_regulation of Gene_expression of Ifng 1 0.05 1.73 0.97
157 INT154255 Tnf Positive_regulation of IL1B 1 0.54 0.94 0.97
158 INT154254 Tnf Positive_regulation of Il6 1 0.36 0.94 0.97
159 INT159111 Il1a Regulation of Gene_expression of Il1b 1 0.49 0.38 0.97
160 INT114320 TNF Positive_regulation of Gene_expression of Il6 1 0.07 1.73 0.97
161 INT103133 TNF Positive_regulation of Gene_expression of IL8 2 0.48 1.26 0.96
162 INT240123 MIR885 Negative_regulation of IL1B 1 0.01 1.57 0.96
163 INT133652 Epo Negative_regulation of Gene_expression of TNF 1 0.35 2.64 0.96
164 INT77142 Binding of IFNG and IL4 2 0.03 1.16 0.95
165 INT171264 TNF Positive_regulation of MMP1 2 0.10 2.05 0.95
166 INT188805 TNF Positive_regulation of Gene_expression of Crp 1 0.15 2.96 0.95
167 INT130722 Binding of IL1B and Nfkb1 1 0.28 1.23 0.95
168 INT100018 TNF Positive_regulation of MAPK1 3 0.24 1.56 0.94
169 INT133050 TNF Positive_regulation of Gene_expression of ICAM1 3 0.67 1.91 0.94
170 INT182024 TNF Positive_regulation of Gene_expression of Il6 1 0.05 1.58 0.94
171 INT129211 RYBP Positive_regulation of Gene_expression of Tnf 1 0.01 1.04 0.94
172 INT130725 Binding of IL1B and Il1rn 1 0.01 1.16 0.93
173 INT81919 Binding of HSF1 and IL1B 1 0.42 0.77 0.93
174 INT155259 RUNX1 Negative_regulation of Tnf 1 0.00 1.48 0.93
175 INT94501 Il2 Positive_regulation of Gene_expression of Ifng 1 0.03 1.63 0.92
176 INT85879 Il12a Positive_regulation of Gene_expression of Ifng 1 0.20 0.89 0.92
177 INT165280 Tnf Positive_regulation of Gene_expression of Nos2 1 0.24 1.02 0.91
178 INT254242 TNF Positive_regulation of Gene_expression of DKK1 1 0.14 1.24 0.91
179 INT256646 Tnf Positive_regulation of Positive_regulation of Nfkb1 1 0.22 1.83 0.9
180 INT161655 Gsr Regulation of Gene_expression of Il1b 1 0.20 1.84 0.9
181 INT222988 TNF Positive_regulation of Protein_catabolism of COL1A1 1 0.01 1.66 0.9
182 INT211128 Binding of P4HB and TNF 1 0.09 0.97 0.9
183 INT211129 Negative_regulation of Binding of P4HB and TNF 1 0.10 0.97 0.9
184 INT120147 Tlr4 Positive_regulation of Tnf 3 0.39 2.14 0.89
185 INT80132 Binding of HLA-B and TNF 1 0.04 1.15 0.89
186 INT142278 Slc8a1 Regulation of Tnf 1 0.14 0.07 0.89
187 INT63943 Il1b Positive_regulation of Localization of Calca 2 0.46 0.98 0.88
188 INT167466 Ccdc80 Negative_regulation of Tnf 1 0.01 0.76 0.88
189 INT136349 Il1b Positive_regulation of Positive_regulation of Oprl1 1 0.22 0.27 0.88
190 INT134311 Tnf Positive_regulation of Protein_catabolism of Nfkbia 1 0.18 0.57 0.88
191 INT91272 Ifng Positive_regulation of Localization of Il6 1 0.29 0 0.88
192 INT209928 IL1B Positive_regulation of MAPK14 2 0.15 1.69 0.87
193 INT116556 Olr1627 Negative_regulation of Regulation of Tnf 1 0.01 1.52 0.87
194 INT224585 IL1B Positive_regulation of IL1RN 1 0.02 1.3 0.87
195 INT97795 IRF6 Positive_regulation of Localization of TNF 3 0.09 1.57 0.86
196 INT152868 Tnf Regulation of Gene_expression of Trpv1 1 0.27 0.25 0.86
197 INT110315 Negative_regulation of ALOX5 Negative_regulation of Gene_expression of TNF 1 0.47 0.74 0.85
198 INT215598 Positive_regulation of P2rx7 Positive_regulation of Localization of TNF 1 0.22 1.44 0.85
199 INT196638 TNF Positive_regulation of F2RL1 2 0.09 1.52 0.84
200 INT196632 IL1B Positive_regulation of F2RL1 2 0.05 1.52 0.84

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of calcidiol 1-monooxygenase activity. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of calcidiol 1-monooxygenase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82
2 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98
3 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81
4 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68
5 INT6852 Localization of TNF 883 0.81 705.95 270.84
6 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97
7 INT6481 Binding of TNF 624 0.48 510.2 214.82
8 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210
9 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58
10 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1
11 INT9660 Regulation of TNF 363 0.62 312.94 139.99
12 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61
13 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03
14 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9
15 INT10166 Localization of Tnf 237 0.81 153.95 88.64
16 INT15769 Gene_expression of Il1b 146 0.78 114.51 75.35
17 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57
18 INT10274 Positive_regulation of Il1b 123 0.70 79.76 73.56
19 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99
20 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35
21 INT10359 Gene_expression of Ifng 159 0.78 79.6 72.14
22 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71
23 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54
24 INT6849 Localization of IL1B 229 0.81 112.56 69.63
25 INT7534 Gene_expression of Ifng 193 0.78 111.02 68.6
26 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85
27 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05
28 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47
29 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18
30 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86
31 INT66029 Negative_regulation of Tnf 100 0.59 84.28 48.16
32 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33
33 INT5307 Regulation of Tnf 87 0.62 78.71 43.4
34 INT13354 Transcription of TNF 108 0.72 85.81 42.32
35 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82
36 INT48075 Positive_regulation of Il1b 71 0.67 48.63 40.48
37 INT5973 Regulation of IL1B 109 0.62 66.6 39.88
38 INT53577 Negative_regulation of Localization of TNF 110 0.59 59.28 35.23
39 INT6484 Binding of IL1B 122 0.47 75.84 35.07
40 INT35406 Localization of Tnf 94 0.81 64.63 31.65
41 INT9347 Localization of Il1b 58 0.81 26.13 31.53
42 INT57692 Positive_regulation of Gene_expression of Il1b 50 0.67 43.54 28.29
43 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59
44 INT10273 Positive_regulation of Gene_expression of Il1b 47 0.68 31.15 26.21
45 INT5948 Regulation of Il1b 44 0.60 22.8 25.4
46 INT56224 Negative_regulation of Gene_expression of Ifng 40 0.58 23.34 25.08
47 INT43486 Positive_regulation of Ifng 52 0.69 32.71 24.77
48 INT10349 Negative_regulation of Il1b 48 0.58 25.53 24.24
49 INT8518 Localization of Ifng 53 0.81 36.68 24.13
50 INT51029 Negative_regulation of Il1b 34 0.57 29.34 23.62
51 INT5055 Positive_regulation of IFNG 89 0.69 64.03 23.05
52 INT48081 Localization of Il1b 46 0.80 21.59 22.4
53 INT66753 Negative_regulation of Positive_regulation of Tnf 45 0.59 35.28 22.33
54 INT8483 Positive_regulation of Positive_regulation of TNF 73 0.67 60.35 22.03
55 INT53575 Regulation of Gene_expression of Tnf 46 0.62 34.35 20.63
56 INT9237 Regulation of Gene_expression of IL1B 49 0.62 30.69 20.34
57 INT53574 Regulation of Tnf 45 0.62 40.68 19.71
58 INT25222 Positive_regulation of Gene_expression of Ifng 32 0.50 24.18 19.58
59 INT66751 Negative_regulation of Localization of Tnf 48 0.59 26 19.36
60 INT66755 Transcription of Tnf 45 0.72 37.1 19.11
61 INT19509 Localization of Ifng 55 0.78 28.25 18.67
62 INT35086 Positive_regulation of Gene_expression of Ifng 40 0.69 22.55 18.35
63 INT36054 Transcription of IL1B 53 0.72 32.64 17.31
64 INT24209 Negative_regulation of Ifng 37 0.57 16.52 17.15
65 INT10169 Positive_regulation of Localization of Tnf 44 0.70 27.71 16.75
66 INT19929 Negative_regulation of Positive_regulation of TNF 52 0.59 38.16 16.51
67 INT49986 Transcription of Tnf 25 0.72 18.3 16.22
68 INT25223 Positive_regulation of Gene_expression of IFNG 41 0.67 36.97 15.89
69 INT10360 Positive_regulation of Ifng 33 0.68 21.73 15.19
70 INT12087 Regulation of Localization of TNF 44 0.62 28.71 15.17
71 INT25266 Positive_regulation of Localization of IL1B 38 0.69 15.89 14.35
72 INT10173 Binding of Tnf 45 0.48 35.6 14.32
73 INT64048 Positive_regulation of Positive_regulation of Tnf 32 0.70 21.24 13.74
74 INT29170 Negative_regulation of Gene_expression of Il1b 25 0.59 16.36 13.68
75 INT4931 Localization of IFNG 53 0.78 33.25 13.65
76 INT19191 Negative_regulation of Localization of IL1B 35 0.58 15.19 13.63
77 INT6478 Negative_regulation of Binding of TNF 36 0.58 30.42 13.31
78 INT7532 Negative_regulation of Gene_expression of Ifng 33 0.59 18.56 13.14
79 INT89404 Regulation of Negative_regulation of TNF 30 0.45 24.47 12.71
80 INT58226 Negative_regulation of Gene_expression of Il1b 24 0.57 18.09 12.68
81 INT51028 Regulation of Il1b 28 0.60 21.15 12.47
82 INT5057 Negative_regulation of Gene_expression of IFNG 23 0.58 8.33 12.3
83 INT9160 Negative_regulation of Ifng 31 0.58 16.37 11.84
84 INT19944 Negative_regulation of IFNG 39 0.58 22.35 10.91
85 INT51265 Phosphorylation of TNF 32 0.81 25.33 10.75
86 INT60434 Negative_regulation of Positive_regulation of Tnf 20 0.46 10.01 10.64
87 INT50196 Transcription of Il1b 25 0.69 19.08 10.43
88 INT80110 Regulation of Positive_regulation of TNF 34 0.44 25.79 9.78
89 INT48078 Regulation of Gene_expression of Il1b 15 0.62 14.78 9.53
90 INT48860 Regulation of Localization of Tnf 25 0.61 20.68 8.78
91 INT53573 Negative_regulation of Localization of Tnf 19 0.59 11.57 8.54
92 INT86411 Negative_regulation of Negative_regulation of TNF 24 0.42 17.6 7.89
93 INT66926 Transcription of Il1b 15 0.69 13.16 7.81
94 INT48077 Positive_regulation of Localization of Il1b 17 0.69 8.8 7.68
95 INT50195 Positive_regulation of Positive_regulation of Il1b 12 0.67 7.41 7.64
96 INT49490 Positive_regulation of Transcription of TNF 19 0.70 14.76 7.58
97 INT68299 Binding of Tnf 17 0.39 12.55 7.49
98 INT11378 Negative_regulation of Positive_regulation of IL1B 23 0.59 10.28 7.26
99 INT66752 Positive_regulation of Transcription of Tnf 15 0.68 10.86 7.26
100 INT5326 Regulation of Ifng 12 0.55 4.56 7.19
101 INT36053 Positive_regulation of Positive_regulation of IL1B 22 0.70 11.41 6.84
102 INT48076 Negative_regulation of Localization of Il1b 10 0.59 3.46 6.58
103 INT48954 Positive_regulation of Localization of Il1b 13 0.53 8.16 6.44
104 INT67130 Negative_regulation of Localization of Il1b 7 0.57 1.36 6.42
105 INT69985 Positive_regulation of Negative_regulation of TNF 21 0.50 13.26 6.31
106 INT84716 Negative_regulation of Positive_regulation of Il1b 9 0.57 5.34 6.27
107 INT74154 Transcription of Ifng 14 0.67 10.33 6.21
108 INT172084 Positive_regulation of Binding of TNF 21 0.50 15.31 6.06
109 INT15803 Regulation of IFNG 21 0.44 12.57 5.98
110 INT80750 Binding of Il1b 11 0.47 7.97 5.95
111 INT5186 Regulation of Ifng 11 0.45 8.78 5.9
112 INT67060 Negative_regulation of Transcription of TNF 17 0.59 12.94 5.88
113 INT6487 Positive_regulation of Positive_regulation of Tnf 21 0.56 16.06 5.64
114 INT55578 Regulation of Gene_expression of Il1b 7 0.62 4.74 5.55
115 INT10705 Binding of Il1b 9 0.36 2.8 5.53
116 INT58145 Positive_regulation of Localization of Tnf 20 0.67 13.33 5.44
117 INT50197 Positive_regulation of Transcription of Il1b 11 0.50 8.95 5.41
118 INT92054 Positive_regulation of Transcription of Tnf 8 0.50 4.93 5.05
119 INT62132 Regulation of Gene_expression of Ifng 12 0.62 1.28 4.77
120 INT55698 Regulation of Binding of TNF 13 0.44 8.98 4.74
121 INT16047 Negative_regulation of Positive_regulation of Il1b 11 0.57 5.27 4.66
122 INT48080 Positive_regulation of Positive_regulation of Il1b 5 0.50 4.3 4.19
123 INT19190 Regulation of Localization of IL1B 14 0.50 8.71 4.12
124 INT66754 Negative_regulation of Transcription of Tnf 11 0.43 8.43 3.93
125 INT23088 Phosphorylation of Tnf 15 0.79 9.85 3.82
126 INT172173 Protein_catabolism of TNF 16 0.96 9.95 3.79
127 INT34054 Regulation of Gene_expression of IFNG 8 0.42 3.69 3.76
128 INT87027 Positive_regulation of Localization of IFNG 12 0.67 5.78 3.35
129 INT65427 Regulation of Positive_regulation of Tnf 7 0.60 3.49 3.22
130 INT66922 Positive_regulation of Transcription of Il1b 7 0.49 6.58 3.14
131 INT95049 Negative_regulation of Regulation of Tnf 4 0.42 1.64 2.84
132 INT6479 Negative_regulation of Binding of IL1B 10 0.43 5.1 2.78
133 INT112147 Positive_regulation of Negative_regulation of Il1b 3 0.49 3.42 2.77
134 INT67078 Binding of Ifng 7 0.48 4.84 2.73
135 INT15197 Regulation of Gene_expression of Ifng 8 0.34 2.66 2.69
136 INT10350 Negative_regulation of Regulation of Il1b 3 0.41 0.58 2.69
137 INT75736 Regulation of Localization of Tnf 6 0.62 4.61 2.67
138 INT11379 Positive_regulation of Negative_regulation of IL1B 9 0.49 7.2 2.64
139 INT111145 Negative_regulation of Positive_regulation of Ifng 7 0.41 2.21 2.61
140 INT15144 Protein_catabolism of IL1B 11 0.92 4.67 2.58
141 INT91669 Negative_regulation of Localization of IFNG 5 0.57 4.1 2.58
142 INT98607 Regulation of Regulation of TNF 8 0.44 6.95 2.56
143 INT16964 Binding of IFNG 27 0.48 14.31 2.45
144 INT73980 Transcription of Ifng 12 0.72 5.42 2.4
145 INT70918 Positive_regulation of Localization of Ifng 5 0.45 2.79 2.33
146 INT67437 Negative_regulation of Localization of Ifng 7 0.47 2.23 2.28
147 INT66804 Negative_regulation of Negative_regulation of Tnf 4 0.56 2.79 2.26
148 INT36055 Positive_regulation of Transcription of IL1B 9 0.49 6.24 2.21
149 INT112784 Positive_regulation of Positive_regulation of IFNG 11 0.49 7.84 2.18
150 INT114898 Regulation of Transcription of TNF 4 0.35 2.69 2.18
151 INT73906 Regulation of Transcription of IL1B 5 0.56 3.46 2.1
152 INT140818 Positive_regulation of Positive_regulation of Ifng 2 0.47 4.2 2.06
153 INT55035 Negative_regulation of Negative_regulation of Il1b 4 0.43 1.46 2.02
154 INT168275 Phosphorylation of Il1b 1 0.79 2.39 2.01
155 INT111530 Positive_regulation of Regulation of Ifng 1 0.41 0.32 2.01
156 INT122649 Positive_regulation of Regulation of Tnf 2 0.49 2.78 1.96
157 INT171323 Phosphorylation of IL1B 5 0.57 4.13 1.94
158 INT116033 Negative_regulation of Transcription of Il1b 4 0.42 2.05 1.94
159 INT11136 Positive_regulation of Localization of Ifng 4 0.49 3.13 1.89
160 INT61627 Transcription of IFNG 6 0.69 4.28 1.83
161 INT14246 Regulation of Positive_regulation of IL1B 7 0.44 3.04 1.77
162 INT77801 Negative_regulation of Binding of Tnf 5 0.42 3.93 1.77
163 INT116498 Negative_regulation of Negative_regulation of IL1B 7 0.41 3.08 1.7
164 INT159957 Positive_regulation of Phosphorylation of Tnf 3 0.49 2.63 1.65
165 INT113716 Positive_regulation of Transcription of Ifng 1 0.53 2.56 1.61
166 INT73901 Negative_regulation of Transcription of IL1B 3 0.53 0.46 1.57
167 INT183791 Positive_regulation of Phosphorylation of TNF 6 0.49 4.72 1.56
168 INT61967 Positive_regulation of Negative_regulation of Tnf 3 0.50 2.46 1.49
169 INT83659 Negative_regulation of Binding of Tnf 3 0.37 1.57 1.42
170 INT56228 Positive_regulation of Positive_regulation of Ifng 2 0.43 2.83 1.4
171 INT94744 Regulation of Transcription of Il1b 3 0.44 2.83 1.26
172 INT11137 Negative_regulation of Localization of Ifng 3 0.38 2.45 1.26
173 INT19923 Regulation of Localization of Ifng 3 0.22 1.1 1.25
174 INT109243 Regulation of Positive_regulation of IFNG 1 0.45 1.27 1.23
175 INT173114 Positive_regulation of Binding of IL1B 6 0.49 2.56 1.22
176 INT111536 Positive_regulation of Negative_regulation of Ifng 1 0.41 0.35 1.18
177 INT129587 Protein_catabolism of Tnf 2 0.86 1.41 1.08
178 INT168276 Negative_regulation of Phosphorylation of Tnf 1 0.19 1.3 1.08
179 INT135027 Regulation of Positive_regulation of Tnf 3 0.38 2.84 1.05
180 INT9348 Regulation of Localization of Il1b 2 0.27 0.14 1.04
181 INT122884 Positive_regulation of Transcription of Ifng 1 0.39 1.08 1.03
182 INT25264 Regulation of Negative_regulation of IL1B 3 0.27 1.17 1.02
183 INT50989 Regulation of Positive_regulation of Il1b 2 0.42 0.86 1.02
184 INT346201 Negative_regulation of Phosphorylation of IL1B 1 0.20 1.69 1.01
185 INT168280 Positive_regulation of Phosphorylation of Il1b 1 0.49 1.1 0.93
186 INT134307 Negative_regulation of Protein_catabolism of Tnf 1 0.41 0.57 0.88
187 INT115822 Regulation of Transcription of Tnf 3 0.35 1.96 0.87
188 INT134310 Positive_regulation of Protein_catabolism of Tnf 1 0.49 0.57 0.87
189 INT103303 Negative_regulation of Transcription of Ifng 6 0.43 2.7 0.83
190 INT43488 Regulation of Positive_regulation of Ifng 1 0.42 0.71 0.83
191 INT64635 Binding of Ifng 2 0.36 0.57 0.81
192 INT136690 Regulation of Negative_regulation of Tnf 5 0.45 3.58 0.78
193 INT102199 Regulation of Transcription of Tnf 2 0.45 2.25 0.78
194 INT11138 Regulation of Localization of Ifng 2 0.56 0.8 0.77
195 INT73240 Negative_regulation of Transcription of IFNG 1 0.41 0.92 0.76
196 INT237158 Negative_regulation of Negative_regulation of Tnf 2 0.13 1.37 0.74
197 INT127822 Negative_regulation of Transcription of Il1b 2 0.42 1.2 0.72
198 INT116009 Regulation of Negative_regulation of Ifng 1 0.44 0.09 0.67
199 INT51263 Regulation of Phosphorylation of TNF 2 0.26 1.06 0.63
200 INT61622 Positive_regulation of Transcription of IFNG 1 0.26 0.29 0.63
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