GO:0060585

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Name positive regulation of prostaglandin-endoperoxide synthase activity
Categary Process
Go Slim No
Go Link GO:0060585
Unique Molecular Interactions 274
Total Molecular Interactions 389
Total Single Events 2771
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of prostaglandin-endoperoxide synthase activity. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of prostaglandin-endoperoxide synthase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT77807 Edn1 Positive_regulation of Gene_expression of Ptgs2 1 0.33 0.53 2.1
2 INT91607 Binding of EDN1 and POMC 1 0.12 0 1.9
3 INT136034 Edn1 Regulation of Trpv1 2 0.66 0.39 1.58
4 INT95275 Binding of Edn1 and Ece1 1 0.32 2.09 1.3
5 INT95274 Regulation of Binding of Edn1 and Ece1 1 0.39 2.09 1.3
6 INT77806 Edn1 Regulation of Gene_expression of Ptgs2 1 0.29 1.24 1.22
7 INT62596 Binding of Edn1 and Nppa 1 0.27 1.77 1.22
8 INT201067 Binding of Edn1 and Ednra 2 0.18 1.36 1.18
9 INT10238 Binding of EDN1 and Calca 1 0.00 1.07 1.06
10 INT152084 Edn1 Negative_regulation of Positive_regulation of Trpv1 1 0.62 0.48 0.96
11 INT136033 Edn1 Positive_regulation of Trpv1 1 0.50 0.34 0.95
12 INT77859 EDN1 Positive_regulation of MC1R 2 0.64 0.34 0.94
13 INT152083 Binding of Edn1 and Trpv1 1 0.38 0.67 0.83
14 INT153765 Positive_regulation of Edn1 Positive_regulation of Gtf3a 2 0.04 2.26 0.82
15 INT106859 EDN1 Positive_regulation of Transcription of MC1R 1 0.22 0 0.82
16 INT53377 Binding of Edn1 and Edn3 1 0.39 0 0.81
17 INT157918 TRPV1 Regulation of Gene_expression of Edn1 1 0.17 0.55 0.81
18 INT157913 Trpv1 Regulation of Gene_expression of Edn1 1 0.29 0.55 0.81
19 INT157915 Prkca Regulation of Gene_expression of Edn1 1 0.17 0.55 0.81
20 INT219911 Edn1 Regulation of Gene_expression of Trpv1 1 0.23 0.57 0.8
21 INT64117 Binding of Edn1 and Ins1 1 0.06 0.85 0.71
22 INT222493 Edn1 Positive_regulation of Localization of Prl 1 0.10 0 0.71
23 INT63557 Binding of Edn1 and Edn3 1 0.23 0.63 0.7
24 INT324900 VEGFA Positive_regulation of Gene_expression of Edn1 1 0.06 1.61 0.69
25 INT278827 Binding of EDN1 and EDNRB 3 0.17 2.7 0.67
26 INT313702 Binding of Edn1 and Fig4 1 0.16 0 0.65
27 INT313698 Binding of Calca and Edn1 1 0.30 0 0.65
28 INT94020 Binding of EDN2 and INSRR 1 0.03 0 0.65
29 INT182266 EDN1 Positive_regulation of Gene_expression of MMP13 1 0.35 2.03 0.63
30 INT219919 EDNRA Negative_regulation of Edn1 1 0.15 0.36 0.63
31 INT178097 Binding of EDN1 and EDNRA 7 0.21 5.97 0.62
32 INT131642 Edn1 Positive_regulation of Positive_regulation of Insrr 1 0.01 0.44 0.6
33 INT178087 EDN1 Positive_regulation of MMP13 2 0.23 1.58 0.59
34 INT130162 Pomc Positive_regulation of Gene_expression of Edn1 1 0.25 0 0.58
35 INT162789 Binding of TLR2 and NOD2 1 0.37 0.51 0.57
36 INT162790 Binding of TLR4 and NOD2 1 0.36 0.51 0.57
37 INT62597 Binding of Edn1 and Vip 1 0.23 0.79 0.54
38 INT110474 YY1 Positive_regulation of Positive_regulation of EDN1 1 0.56 0.15 0.53
39 INT130160 Pomc Regulation of Edn1 1 0.25 0 0.53
40 INT278825 Positive_regulation of Binding of EDN1 and EDNRB 3 0.16 1.24 0.49
41 INT94015 Binding of EDN1 and INSRR 1 0.04 0 0.49
42 INT94024 Binding of EDN1 and EDN3 1 0.27 0 0.49
43 INT94018 Binding of EDN2 and EDN3 1 0.19 0 0.48
44 INT99571 Edn1 Positive_regulation of Localization of Ednra 1 0.01 0.32 0.47
45 INT110476 EDN1 Positive_regulation of Localization of PRKCZ 1 0.25 0.07 0.46
46 INT50497 Edn1 Positive_regulation of Pla2g1b 1 0.01 0.23 0.45
47 INT110475 EDN1 Regulation of PRKCA 1 0.05 0.07 0.45
48 INT219910 EDN1 Positive_regulation of Positive_regulation of EDNRA 1 0.00 0.3 0.45
49 INT313704 Smn1 Negative_regulation of Gene_expression of Edn1 1 0.32 0 0.42
50 INT153766 Edn1 Positive_regulation of Gtf3a 1 0.04 1.25 0.41
51 INT230724 EDN1 Positive_regulation of EDNRA 3 0.24 4.12 0.39
52 INT99399 Penk Positive_regulation of Edn1 1 0.00 0 0.38
53 INT99400 Gast Positive_regulation of Edn1 1 0.00 0 0.38
54 INT173704 Binding of PCOS1 and Edn1 1 0.01 0.99 0.37
55 INT313701 Calca Negative_regulation of Binding of Edn1 1 0.30 0.14 0.37
56 INT152314 Il18 Regulation of Edn1 1 0.02 0.22 0.36
57 INT201068 Binding of Edn1 and Ednrb 2 0.18 1.23 0.35
58 INT152316 Ifng Regulation of Edn1 1 0.01 0.22 0.35
59 INT203395 Edn1 Positive_regulation of Vegfa 1 0.06 1.59 0.35
60 INT161796 Binding of ECE1 and EDN1 2 0.21 2.23 0.34
61 INT207576 RETN Positive_regulation of Gene_expression of EDN1 1 0.05 0.78 0.33
62 INT143567 Edn1 Regulation of Ptgs2 1 0.26 0.17 0.33
63 INT99842 Edn1 Negative_regulation of Localization of Ren 1 0.24 0.43 0.32
64 INT67266 Edn1 Negative_regulation of Ece1 1 0.19 0.17 0.32
65 INT182262 EDN1 Positive_regulation of Gene_expression of NOS2 1 0.28 0.79 0.31
66 INT71519 Edn1 Positive_regulation of Gene_expression of Adarb1 1 0.02 0.48 0.31
67 INT191505 NLRP3 Positive_regulation of Protein_catabolism of EDN1 1 0.00 1.1 0.28
68 INT54639 Edn3 Negative_regulation of Edn2 1 0.00 0 0.28
69 INT239226 Binding of Edn1 and Ednra 2 0.06 1.59 0.26
70 INT256227 Binding of EDN1 and VEGFA 1 0.18 2.92 0.25
71 INT178095 EDN1 Positive_regulation of MMP3 1 0.04 0.88 0.24
72 INT178076 EDN1 Positive_regulation of MMP2 1 0.04 0.88 0.24
73 INT178085 EDN1 Positive_regulation of MMP7 1 0.06 0.89 0.24
74 INT178141 EDN1 Positive_regulation of Timp1 1 0.30 0.89 0.24
75 INT178075 EDN1 Positive_regulation of PLAU 1 0.06 0.95 0.24
76 INT178104 EDN1 Positive_regulation of Localization of TIMP1 1 0.05 0.83 0.24
77 INT178094 Positive_regulation of EDN1 Positive_regulation of PLAU 1 0.06 0.95 0.24
78 INT178142 EDN1 Positive_regulation of Localization of Timp1 1 0.28 0.89 0.24
79 INT178077 EDN1 Positive_regulation of MMP9 1 0.06 0.88 0.24
80 INT290378 NOD2 Negative_regulation of TLR2 1 0.27 0.83 0.23
81 INT290377 NOD2 Negative_regulation of Positive_regulation of TLR2 1 0.24 0.95 0.23
82 INT182272 EDN1 Regulation of Gene_expression of MMP13 1 0.26 0.87 0.22
83 INT91686 Mb Positive_regulation of Edn1 1 0.03 0.29 0.22
84 INT182265 EDN1 Positive_regulation of NOS2 1 0.24 0.56 0.22
85 INT182263 EDN1 Positive_regulation of MMP1 1 0.15 0.43 0.21
86 INT178074 EDN1 Positive_regulation of Phosphorylation of PXN 1 0.05 0.82 0.2
87 INT274094 EDN1 Positive_regulation of AGT 1 0.16 0.95 0.2
88 INT182258 EDN1 Positive_regulation of Positive_regulation of MMP1 1 0.15 0.47 0.19
89 INT182271 EDN1 Positive_regulation of Localization of MMP13 1 0.27 0.47 0.19
90 INT219915 Edn1 Regulation of Positive_regulation of Trpv1 1 0.33 0 0.18
91 INT140096 Gtf3a Positive_regulation of Gene_expression of Edn1 1 0.02 0.44 0.18
92 INT171386 Edn1 Positive_regulation of Mapk1 1 0.05 0.13 0.18
93 INT60778 Edn1 Positive_regulation of EDNRA 1 0.00 0 0.18
94 INT284450 Edn1 Positive_regulation of Gene_expression of MMP9 1 0.01 0.3 0.18
95 INT140094 Ifng Regulation of Gene_expression of Edn1 1 0.18 0.44 0.18
96 INT178073 EDN1 Positive_regulation of PTK2 1 0.03 1.02 0.17
97 INT203759 Binding of EDN1 and TNF 1 0.16 0.71 0.16
98 INT324899 Edn1 Positive_regulation of Positive_regulation of Mmp9 1 0.10 0.66 0.16
99 INT94022 Positive_regulation of Binding of EDN1 and INSRR 1 0.06 0 0.16
100 INT178079 EDN1 Positive_regulation of Positive_regulation of AKT1 1 0.05 0.91 0.16
101 INT94021 Binding of EDN1 and EDN2 1 0.26 0 0.16
102 INT204791 Binding of Spg7 and Nod2 1 0.03 0.5 0.16
103 INT94013 Positive_regulation of Binding of EDN2 and INSRR 1 0.04 0 0.16
104 INT94014 Positive_regulation of Binding of EDN1 and EDN3 1 0.36 0 0.16
105 INT94023 Positive_regulation of Binding of EDN2 and EDN3 1 0.25 0 0.16
106 INT204789 Binding of Tlr2 and Nod2 1 0.23 0.44 0.16
107 INT324894 Edn1 Positive_regulation of Gene_expression of Mmp3 1 0.07 0.66 0.16
108 INT278828 Positive_regulation of Binding of EDN1 and EDNRA 1 0.06 0.51 0.15
109 INT21509 Agt Regulation of Edn1 1 0.53 0 0.15
110 INT182261 EDN1 Regulation of Gene_expression of MMP1 1 0.17 0.7 0.15
111 INT318305 Binding of NOD2 and NLRP3 1 0.08 1.76 0.15
112 INT50500 Edn1 Positive_regulation of PTGS1 1 0.00 0.07 0.14
113 INT324898 Ece1 Regulation of Gene_expression of Edn1 1 0.17 0.8 0.14
114 INT161799 Positive_regulation of Binding of ECE1 and EDN1 1 0.07 0.68 0.14
115 INT332689 Binding of Edn1 and Ros1 1 0.08 0.71 0.14
116 INT161798 Positive_regulation of Binding of EDN1 and ING1 1 0.06 0.66 0.13
117 INT161800 Binding of EDN1 and ING1 1 0.05 0.65 0.13
118 INT145830 Mdp1 Positive_regulation of Nod2 1 0.34 0.52 0.13
119 INT178083 EDN1 Positive_regulation of Gene_expression of VEGFA 1 0.09 1.8 0.13
120 INT206065 EDN1 Positive_regulation of IL6 1 0.03 0.47 0.12
121 INT178101 EDN1 Negative_regulation of Phosphorylation of BCL2 1 0.03 1 0.12
122 INT77863 EDN1 Positive_regulation of POMC 1 0.50 0.34 0.12
123 INT182273 EDN1 Regulation of Gene_expression of BAD 1 0.11 0.73 0.12
124 INT180445 Edn1 Positive_regulation of Rhoa 1 0.08 0.57 0.11
125 INT182270 EDN1 Positive_regulation of Gene_expression of MMP1 1 0.18 0.55 0.1
126 INT181569 Binding of Edn1 and Mapk8 1 0.09 2.7 0.1
127 INT181570 Binding of Edn1 and Mapk1 1 0.13 2.72 0.1
128 INT6674 Edn1 Positive_regulation of Gene_expression of FOS 1 0.08 0.19 0.1
129 INT139476 Edn1 Positive_regulation of Ednra 1 0.00 1.07 0.1
130 INT10904 Edn1 Regulation of Localization of Nppb 1 0.22 0.54 0.1
131 INT92956 Edn1 Regulation of Positive_regulation of Nos2 1 0.18 0.17 0.09
132 INT332688 Ros1 Positive_regulation of Binding of Edn1 1 0.10 0.57 0.09
133 INT230750 Crp Positive_regulation of Edn1 1 0.10 0.27 0.09
134 INT92957 Edn1 Regulation of Gene_expression of Nos2 1 0.18 0.17 0.09
135 INT242257 Binding of EDN1 and ELF3 1 0.17 0.21 0.08
136 INT181584 Binding of EDNRB and Edn1 1 0.46 0.85 0.08
137 INT181583 Binding of Edn1 and Positive_regulation of NOS1 1 0.02 0.86 0.08
138 INT178100 Gene_expression of EDNRB Positive_regulation of EDN1 1 0.17 1.11 0.08
139 INT113369 Edn1 Regulation of Adarb1 1 0.02 0.14 0.08
140 INT178081 Negative_regulation of EDN1 Positive_regulation of HIF1A 1 0.04 1.18 0.08
141 INT178080 EDN1 Positive_regulation of HIF1A 1 0.05 1.05 0.08
142 INT331626 Edn1 Positive_regulation of Itk 1 0.00 0.57 0.07
143 INT182269 EDN1 Positive_regulation of Localization of MMP1 1 0.17 0.31 0.07
144 INT192908 Edn1 Positive_regulation of Ednra 1 0.21 0.35 0.07
145 INT242258 ELF3 Negative_regulation of EDN1 1 0.15 0.09 0.07
146 INT309941 Edn1 Positive_regulation of Tlr2 1 0.02 1.31 0.07
147 INT172382 AGT Positive_regulation of Localization of EDN1 1 0.03 0.34 0.07
148 INT182268 Negative_regulation of MAPK14 Negative_regulation of Gene_expression of EDN1 1 0.22 0.31 0.07
149 INT192907 Edn1 Positive_regulation of Ednrb 1 0.10 0.35 0.07
150 INT182274 MAPK14 Negative_regulation of Gene_expression of EDN1 1 0.22 0.31 0.07
151 INT191219 Edn1 Positive_regulation of Amigo2 1 0.06 1.26 0.07
152 INT324896 Ece1 Positive_regulation of Negative_regulation of Edn1 1 0.19 0.42 0.07
153 INT172381 AVP Positive_regulation of Localization of EDN1 1 0.01 0.34 0.07
154 INT178096 EDN1 Positive_regulation of Gene_expression of EDNRB 1 0.17 1.01 0.07
155 INT181645 Edn1 Positive_regulation of NOS3 1 0.02 0.21 0.07
156 INT178090 EDN1 Positive_regulation of Phosphorylation of GJA1 1 0.09 0.88 0.06
157 INT191216 Binding of Edn1 and Cotl1 1 0.14 0.63 0.05
158 INT182259 EDN1 Positive_regulation of Gene_expression of TIMP1 1 0.01 0.27 0.05
159 INT180668 Edn1 Positive_regulation of Gene_expression of Col1a1 1 0.02 0 0.05
160 INT182264 EDN1 Positive_regulation of Positive_regulation of MAPK14 1 0.26 0.1 0.05
161 INT180667 Edn1 Regulation of Ecm1 1 0.04 0 0.05
162 INT213263 INS Positive_regulation of EDN1 1 0.12 0.54 0.04
163 INT178091 EDN1 Positive_regulation of Gene_expression of PTGER2 1 0.01 0.74 0.04
164 INT353314 Edn1 Positive_regulation of Kalrn 1 0.03 0.21 0.04
165 INT229371 Positive_regulation of Pparg Negative_regulation of Gene_expression of Edn1 1 0.01 0.92 0.04
166 INT178098 EDN1 Positive_regulation of Transcription of VEGFA 1 0.08 0.76 0.04
167 INT332684 Binding of Edn1 and Lep 1 0.09 1.11 0.04
168 INT306514 EDN1 Positive_regulation of EDNRB 1 0.11 0.98 0.04
169 INT353317 Edn1 Positive_regulation of RHOA 1 0.19 0.16 0.04
170 INT178082 EDN1 Positive_regulation of VEGFA 1 0.08 0.77 0.04
171 INT323623 Binding of Adm and Edn1 1 0.04 0.77 0.03
172 INT239229 Regulation of Binding of Edn1 and Ednra 1 0.01 0.37 0.03
173 INT321407 EDN1 Positive_regulation of Phosphorylation of IRS1 1 0.06 1.07 0.03
174 INT345298 NLRP3 Positive_regulation of Localization of Edn1 1 0.01 0.94 0.03
175 INT256228 EDNRB Positive_regulation of EDN1 1 0.26 0.62 0.03
176 INT239225 Binding of Edn1 and Ednrb 1 0.02 0.36 0.03
177 INT292081 Binding of EDN1 and NCOR2 1 0.00 0.98 0.03
178 INT239228 Regulation of Binding of Edn1 and Ednrb 1 0.02 0.37 0.03
179 INT239224 Positive_regulation of Binding of Edn1 and Ednrb 1 0.02 0.37 0.03
180 INT222259 EIF4E Regulation of Negative_regulation of NOD2 1 0.13 0.1 0
181 INT213030 Hdl1 Regulation of Gene_expression of Edn1 1 0.06 0.88 0
182 INT10901 Edn1 Positive_regulation of Localization of Nppb 1 0.39 0.68 0
183 INT6676 Binding of Edn1 and Regulation of Gene_expression of CREB1 1 0.04 0.15 0
184 INT10909 Edn1 Positive_regulation of Nppb 1 0.39 0.16 0
185 INT186689 Binding of ACHE and Edn1 1 0.28 0 0
186 INT186685 Edn1 Regulation of Gene_expression of Il6 1 0.11 1.1 0
187 INT284143 EDN1 Positive_regulation of CA2 1 0.03 0.37 0
188 INT192910 Edn1 Regulation of Col4a1 1 0.16 0.49 0
189 INT10902 Edn1 Regulation of Avp 1 0.27 0.35 0
190 INT182267 EDN1 Regulation of Gene_expression of NOS2 1 0.36 0 0
191 INT111394 Binding of Edn1 and Pscs 1 0.25 0 0
192 INT191220 Cotl1 Positive_regulation of Edn1 1 0.19 0.69 0
193 INT191218 Edn1 Regulation of Positive_regulation of Prkcg 1 0.14 0.32 0
194 INT280620 Fig4 Regulation of Gene_expression of Edn1 1 0.03 0 0
195 INT356497 CGA Regulation of Edn1 1 0.02 0 0
196 INT6662 Edn1 Positive_regulation of Positive_regulation of Fos 1 0.00 0.17 0
197 INT182257 EDN1 Positive_regulation of Phosphorylation of AKT1 1 0.21 0.05 0
198 INT192911 Edn1 Positive_regulation of Positive_regulation of Col4a1 1 0.24 0.13 0
199 INT10905 Edn1 Regulation of Agt 1 0.11 0.35 0
200 INT230723 ERVW-1 Positive_regulation of Gene_expression of EDN1 1 0.00 1.95 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of prostaglandin-endoperoxide synthase activity. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of prostaglandin-endoperoxide synthase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5781 Gene_expression of Edn1 190 0.78 99.1 46
2 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19
3 INT6364 Gene_expression of Edn1 123 0.78 73.76 28.43
4 INT6726 Positive_regulation of Edn1 118 0.70 65.96 24.07
5 INT15390 Positive_regulation of Edn1 64 0.70 47.36 23.8
6 INT8662 Positive_regulation of EDN1 144 0.70 125.34 19.59
7 INT5048 Binding of Edn1 55 0.47 18.86 19.16
8 INT9191 Localization of EDN1 94 0.81 57.01 14.78
9 INT8904 Positive_regulation of Gene_expression of EDN1 66 0.70 65.4 14.42
10 INT5806 Regulation of Edn1 63 0.62 23.46 13.88
11 INT6365 Localization of Edn1 56 0.81 18.84 13.83
12 INT21979 Negative_regulation of EDN1 52 0.58 24.65 12.55
13 INT10184 Regulation of EDN1 44 0.62 23.78 10.06
14 INT6361 Localization of Edn1 30 0.81 19.09 9.7
15 INT17101 Positive_regulation of Gene_expression of Edn1 24 0.69 24.9 8.86
16 INT12095 Negative_regulation of Edn1 26 0.59 12.01 8.79
17 INT10237 Binding of EDN1 40 0.48 16 8.48
18 INT10899 Positive_regulation of Gene_expression of Edn1 32 0.70 24.88 7.65
19 INT103909 Gene_expression of NOD2 37 0.77 21.9 7.36
20 INT10104 Negative_regulation of Edn1 43 0.59 15.63 7.2
21 INT17803 Regulation of Edn1 14 0.54 4.75 4.71
22 INT75440 Regulation of Binding of Edn1 4 0.38 1.41 4.33
23 INT95272 Regulation of Gene_expression of Edn1 19 0.53 17.85 3.42
24 INT53374 Binding of Edn1 17 0.43 11.66 2.98
25 INT103910 Binding of NOD2 19 0.47 12.24 2.93
26 INT100014 Negative_regulation of Gene_expression of EDN1 17 0.42 7.85 2.71
27 INT55853 Positive_regulation of Positive_regulation of Edn1 11 0.61 6.5 2.21
28 INT49253 Regulation of Gene_expression of EDN1 11 0.61 3.92 2.07
29 INT49259 Regulation of Localization of EDN1 8 0.61 6.29 1.92
30 INT76834 Negative_regulation of Gene_expression of Edn1 4 0.43 1.76 1.88
31 INT117221 Positive_regulation of Gene_expression of NOD2 7 0.65 4.39 1.83
32 INT79815 Positive_regulation of Localization of Edn1 7 0.68 2.07 1.79
33 INT162793 Regulation of NOD2 6 0.45 7.61 1.78
34 INT8661 Positive_regulation of Positive_regulation of EDN1 10 0.66 10.9 1.76
35 INT173700 Negative_regulation of Binding of Edn1 2 0.58 0.41 1.76
36 INT14842 Negative_regulation of Binding of EDN1 4 0.57 0.67 1.66
37 INT181579 Phosphorylation of Edn1 1 0.71 8.59 1.51
38 INT15407 Positive_regulation of Positive_regulation of Edn1 5 0.62 3.69 1.49
39 INT24768 Negative_regulation of Gene_expression of Edn1 10 0.43 2.85 1.48
40 INT65640 Positive_regulation of Localization of Edn1 2 0.42 2.16 1.48
41 INT117219 Positive_regulation of NOD2 9 0.69 4.66 1.31
42 INT204766 Gene_expression of Nod2 4 0.75 4.14 1.3
43 INT17802 Transcription of Edn1 6 0.24 6.31 1.18
44 INT49258 Negative_regulation of Positive_regulation of EDN1 10 0.43 7.24 1.12
45 INT61123 Localization of Edn2 1 0.55 0.27 1.05
46 INT154227 Regulation of Gene_expression of NOD2 3 0.44 3.38 0.99
47 INT69803 Regulation of Localization of Edn1 3 0.62 0.79 0.98
48 INT49255 Protein_catabolism of EDN1 5 0.99 2.66 0.95
49 INT69422 Positive_regulation of Negative_regulation of EDN1 2 0.43 0.96 0.95
50 INT49254 Transcription of EDN1 5 0.69 2.42 0.94
51 INT152081 Phosphorylation of Edn1 1 0.53 0.39 0.9
52 INT61591 Negative_regulation of Localization of EDN1 11 0.59 2.09 0.85
53 INT57433 Positive_regulation of Binding of EDN1 3 0.49 0.62 0.82
54 INT186681 Gene_expression of Edn2 2 0.09 1.01 0.76
55 INT61121 Regulation of Regulation of Edn1 1 0.43 0.2 0.75
56 INT8614 Negative_regulation of Edn2 3 0.06 0.07 0.73
57 INT59970 Positive_regulation of Binding of Edn1 2 0.40 1.11 0.71
58 INT21957 Negative_regulation of Negative_regulation of Edn1 5 0.43 1.34 0.69
59 INT49252 Positive_regulation of Localization of EDN1 17 0.69 6.55 0.66
60 INT100396 Transcription of Edn1 7 0.69 2.48 0.66
61 INT49256 Regulation of Positive_regulation of EDN1 2 0.45 2.5 0.65
62 INT7153 Positive_regulation of Regulation of Edn1 2 0.35 1.97 0.57
63 INT135715 Negative_regulation of Localization of Edn1 5 0.42 1.7 0.56
64 INT63910 Regulation of Positive_regulation of Edn1 2 0.43 0.64 0.54
65 INT131641 Negative_regulation of Negative_regulation of Edn1 1 0.37 0.31 0.52
66 INT181581 Regulation of Positive_regulation of Edn1 4 0.23 3.76 0.51
67 INT8663 Positive_regulation of EDN2 3 0.38 0.65 0.5
68 INT204781 Positive_regulation of Nod2 6 0.45 2.79 0.46
69 INT55372 Regulation of Localization of Edn1 2 0.38 0.64 0.46
70 INT57434 Regulation of Regulation of EDN1 1 0.40 0.47 0.44
71 INT222266 Transcription of NOD2 5 0.68 0.76 0.43
72 INT81433 Negative_regulation of Positive_regulation of Edn1 4 0.39 0.81 0.38
73 INT171764 Localization of NOD2 2 0.74 0.86 0.37
74 INT113368 Regulation of Negative_regulation of Edn1 1 0.45 0.71 0.35
75 INT141013 Regulation of Gene_expression of Edn1 2 0.24 0.55 0.34
76 INT183240 Negative_regulation of NOD2 6 0.43 1.52 0.33
77 INT16368 Protein_catabolism of Edn1 2 0.72 0.18 0.31
78 INT244148 Positive_regulation of Positive_regulation of NOD2 1 0.47 0.68 0.31
79 INT222270 Regulation of Localization of NOD2 1 0.45 0.63 0.28
80 INT346895 Positive_regulation of Gene_expression of Nod2 1 0.33 0.74 0.28
81 INT84038 Protein_catabolism of Edn1 2 0.86 0.69 0.26
82 INT346896 Binding of Nod2 1 0.21 0.72 0.26
83 INT8660 Positive_regulation of Positive_regulation of EDN2 2 0.38 0.23 0.22
84 INT346899 Regulation of Positive_regulation of Nod2 1 0.18 0.75 0.22
85 INT67265 Positive_regulation of Negative_regulation of Edn1 1 0.61 0.05 0.21
86 INT156920 Phosphorylation of EDN1 4 0.61 0.66 0.19
87 INT53372 Positive_regulation of Regulation of Edn1 1 0.50 0 0.19
88 INT100397 Regulation of Transcription of Edn1 1 0.00 0.1 0.19
89 INT26353 Binding of Edn2 1 0.01 0 0.17
90 INT323040 Gene_expression of EDN2 1 0.32 0.13 0.13
91 INT222274 Regulation of Regulation of NOD2 1 0.27 0.45 0.13
92 INT284152 Regulation of Transcription of EDN1 1 0.32 0.44 0.13
93 INT6362 Negative_regulation of Localization of Edn1 3 0.16 1.92 0.12
94 INT15391 Negative_regulation of Positive_regulation of Edn1 2 0.07 0.1 0.1
95 INT170744 Positive_regulation of Transcription of Edn1 2 0.20 1.3 0.1
96 INT323038 Regulation of Positive_regulation of EDN2 1 0.21 0 0.1
97 INT204777 Negative_regulation of Localization of Nod2 1 0.28 0.61 0.09
98 INT49257 Positive_regulation of Transcription of EDN1 2 0.46 1.1 0.08
99 INT126441 Negative_regulation of Transcription of Edn1 1 0.40 0.17 0.08
100 INT204779 Localization of Nod2 1 0.48 0.6 0.08
101 INT204770 Regulation of Nod2 1 0.29 0.66 0.07
102 INT222267 Regulation of Transcription of NOD2 1 0.45 0 0.05
103 INT346893 Negative_regulation of Gene_expression of Nod2 1 0.28 0.13 0.04
104 INT323037 Negative_regulation of EDN2 1 0.20 0.23 0
105 INT284053 Positive_regulation of Positive_regulation of Nod2 1 0.25 0.08 0
106 INT280682 Positive_regulation of Transcription of Edn1 1 0.34 0 0
107 INT49261 Negative_regulation of Protein_catabolism of EDN1 1 0.58 0 0
108 INT323036 Regulation of EDN2 1 0.13 0 0
109 INT323041 Binding of EDN2 1 0.18 0.12 0
110 INT222273 Positive_regulation of Regulation of NOD2 1 0.46 0.09 0
111 INT323039 Regulation of Binding of EDN2 1 0.21 0.12 0
112 INT181578 Negative_regulation of Phosphorylation of Edn1 1 0.37 0.1 0
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