GO:0060612

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Name adipose tissue development
Categary Process
Go Slim No
Go Link GO:0060612
Unique Molecular Interactions 367
Total Molecular Interactions 525
Total Single Events 3465
Pain Genes Associated 21

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for adipose tissue development. They are ordered first by their pain relevance and then by number of times they were reported for adipose tissue development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT83169 Binding of Cck and Lep 7 0.42 1.58 2.78
2 INT278948 LEP Positive_regulation of Gene_expression of PTGER2 1 0.09 4.04 2.69
3 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
4 INT83170 Lep Regulation of Cck 5 0.43 0.68 1.96
5 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
6 INT84886 APC Regulation of PPARD 1 0.51 1.57 1.26
7 INT117311 HP Positive_regulation of Lep 1 0.00 1.78 1.01
8 INT278962 LEP Positive_regulation of CPOX 1 0.05 1.33 1
9 INT83987 Ngf Regulation of Atf2 1 0.52 0.49 1
10 INT278940 LEP Positive_regulation of Gene_expression of IL8 1 0.34 1.68 0.96
11 INT130948 Amt Regulation of Gene_expression of LEP 1 0.00 1.04 0.78
12 INT130949 Amt Regulation of LEP 1 0.00 1.04 0.77
13 INT278958 LEP Positive_regulation of IL1B 1 0.33 1.91 0.74
14 INT214163 Binding of Lep and Nts 1 0.04 0.21 0.74
15 INT89009 Lep Positive_regulation of Cck 2 0.67 0.43 0.69
16 INT278956 LEP Regulation of Gene_expression of IL8 1 0.30 1.11 0.69
17 INT278968 LEP Regulation of Gene_expression of IL6 1 0.29 1.11 0.69
18 INT278951 LEP Regulation of Gene_expression of PTGER2 1 0.07 1.11 0.69
19 INT231533 IL4 Positive_regulation of LRP5 1 0.00 0.87 0.67
20 INT278965 LEP Positive_regulation of Gene_expression of NOS2 2 0.29 2.12 0.66
21 INT110458 Binding of Atf2 and Mapk8 1 0.35 0 0.66
22 INT153797 NUBPL Negative_regulation of PPARD 1 0.02 0.69 0.64
23 INT323773 Binding of Il6 and Lep 1 0.29 3.54 0.6
24 INT349083 Binding of Lep and Rtn1 1 0.09 1.68 0.57
25 INT91339 Binding of Lep and Cck 1 0.28 0.34 0.56
26 INT113162 Lep Positive_regulation of Positive_regulation of Insrr 1 0.03 0 0.55
27 INT253834 Cck Regulation of Lep 1 0.19 0.23 0.55
28 INT204087 IL1B Positive_regulation of Gene_expression of LEP 1 0.09 2.6 0.54
29 INT214160 Binding of Lep and Mc4r 1 0.29 1.31 0.53
30 INT214143 Binding of Lep and Pomc 1 0.27 1.2 0.53
31 INT162890 Negative_regulation of Binding of LEP and Tnf 1 0.03 0.49 0.48
32 INT162889 Binding of LEP and Tnf 1 0.03 0.49 0.48
33 INT132509 Binding of LEP and Cck 1 0.13 0.16 0.45
34 INT80053 Negative_regulation of Binding of ACAT1 and NA 1 0.01 0.25 0.45
35 INT80052 Binding of ACAT1 and NA 1 0.01 0.24 0.44
36 INT283714 Positive_regulation of Binding of Id2 and Homer1 1 0.08 1.34 0.42
37 INT283713 Binding of Id2 and Homer1 1 0.06 1.34 0.42
38 INT323880 Binding of BMI1 and LEP 1 0.02 3.97 0.41
39 INT83171 Cck Regulation of Lep 1 0.30 0.09 0.4
40 INT97395 Lep Positive_regulation of Stat3 1 0.67 0.42 0.4
41 INT143747 Binding of IL6 and LEP 2 0.04 4.05 0.38
42 INT151546 Adcy1 Positive_regulation of Atf2 1 0.36 0.37 0.37
43 INT300488 Binding of CRP and LEP 1 0.46 2.03 0.37
44 INT151549 Regulation of Adcy1 Positive_regulation of Atf2 1 0.33 0.37 0.37
45 INT84887 APC Negative_regulation of Gene_expression of PPARD 1 0.36 0.55 0.37
46 INT151551 Regulation of Camk4 Positive_regulation of Atf2 1 0.34 0.36 0.37
47 INT151547 Camk4 Positive_regulation of Atf2 1 0.38 0.36 0.37
48 INT226785 Angpt2 Positive_regulation of Localization of Lep 1 0.01 1.65 0.36
49 INT278966 MAPK14 Positive_regulation of Gene_expression of LEP 1 0.16 0.62 0.36
50 INT278949 JAK3 Positive_regulation of Gene_expression of LEP 1 0.42 0.63 0.36
51 INT323885 LEP Regulation of Gene_expression of NOS2 1 0.26 1.07 0.35
52 INT213484 Binding of Lep and Pik3c3 1 0.01 0 0.35
53 INT207184 Binding of Adipoq and Lep 1 0.25 2.45 0.33
54 INT323870 LEP Regulation of Gene_expression of MMP13 1 0.21 1.76 0.33
55 INT303993 Lep Positive_regulation of Gene_expression of IL2 1 0.15 0.24 0.33
56 INT110464 Cpe Regulation of Phosphorylation of Atf2 1 0.02 0 0.32
57 INT105873 Ins1 Negative_regulation of Positive_regulation of Lep 1 0.27 0.67 0.31
58 INT278942 LEP Regulation of IL6 1 0.29 0.61 0.31
59 INT278939 LEP Regulation of IL8 1 0.13 0.61 0.31
60 INT213485 Lep Positive_regulation of Localization of Grin2a 1 0.19 0 0.31
61 INT110459 Binding of Atf2 and Jun 1 0.32 0 0.31
62 INT278969 LEP Regulation of PTGER2 1 0.03 0.6 0.31
63 INT105874 Lep Negative_regulation of Positive_regulation of Ins1 1 0.27 0.67 0.31
64 INT226989 Lias Regulation of Gene_expression of Lep 1 0.10 0.91 0.3
65 INT278961 IL6 Regulation of Gene_expression of LEP 1 0.29 0.89 0.3
66 INT303983 Lep Positive_regulation of CXCL10 1 0.06 0.31 0.29
67 INT333886 Binding of Lep and Positive_regulation of Gene_expression of Nos2 1 0.39 0.73 0.29
68 INT303998 Lep Positive_regulation of Localization of IL1RAPL1 1 0.04 0.31 0.29
69 INT333887 Binding of Lep and Positive_regulation of Gene_expression of Il1 1 0.17 0.73 0.29
70 INT303995 Lep Positive_regulation of PSME1 1 0.09 0.32 0.29
71 INT303984 Lep Positive_regulation of Gene_expression of IL8 1 0.06 0.85 0.28
72 INT159201 Binding of Ppard and Ppara 1 0.01 0.68 0.28
73 INT264841 NAMPT Positive_regulation of GRM5 1 0.01 0.72 0.27
74 INT100531 Cck Positive_regulation of Lep 1 0.70 0.15 0.26
75 INT228611 Binding of DNMT3B and LEP 1 0.04 0 0.25
76 INT218732 Lep Regulation of Gene_expression of Trh 1 0.19 0.18 0.25
77 INT169048 Positive_regulation of Binding of Atf2 and Sult4a1 1 0.38 0.11 0.24
78 INT125748 Binding of LEP and Gh 1 0.00 0.52 0.24
79 INT169054 Binding of Atf2 and Sult4a1 1 0.37 0.11 0.24
80 INT306795 Binding of LEP and SFTPD 1 0.08 1.13 0.23
81 INT303988 Lep Positive_regulation of Gene_expression of ISYNA1 1 0.06 0.55 0.23
82 INT323883 BMI1 Regulation of LEP 1 0.02 2.39 0.23
83 INT255942 Elk1 Regulation of Binding of ATF2 1 0.07 0.12 0.22
84 INT255842 CREB1 Regulation of Binding of ATF2 1 0.03 0.12 0.22
85 INT255837 ATF2 Regulation of Binding of CREB1 1 0.03 0.12 0.22
86 INT255941 ATF2 Regulation of Transcription of Elk1 1 0.07 0.12 0.22
87 INT255835 ATF2 Regulation of Transcription of CREB1 1 0.03 0.12 0.22
88 INT102937 Gnrh1 Positive_regulation of Gene_expression of Lep 1 0.50 0 0.22
89 INT255839 CREB1 Regulation of Transcription of ATF2 1 0.03 0.12 0.22
90 INT255937 ATF2 Regulation of Binding of Elk1 1 0.07 0.12 0.22
91 INT255939 Elk1 Regulation of Transcription of ATF2 1 0.07 0.12 0.22
92 INT110653 Lep Regulation of Localization of Cck 1 0.06 0.22 0.22
93 INT269180 LEP Positive_regulation of Localization of TNF 1 0.01 0.99 0.21
94 INT323873 LEP Regulation of Gene_expression of TIMP2 1 0.31 0.63 0.21
95 INT207185 Binding of Bmi1 and Lep 1 0.01 1.7 0.21
96 INT335888 Lrp5 Negative_regulation of Gene_expression of Tph1 1 0.22 0.15 0.21
97 INT222482 Lep Positive_regulation of Localization of Gh1 1 0.02 1.02 0.2
98 INT304001 Lep Negative_regulation of ICAM3 1 0.07 0.35 0.2
99 INT333889 Lep Regulation of Col7a1 1 0.04 0.41 0.2
100 INT303979 Lep Positive_regulation of ITGB2 1 0.11 0.35 0.2
101 INT256576 Lep Regulation of Localization of Ins1 1 0.57 2.08 0.2
102 INT303991 Lep Negative_regulation of SELL 1 0.04 0.35 0.2
103 INT217661 LEP Positive_regulation of INS 2 0.25 1.85 0.19
104 INT327814 Rab8a Regulation of Regulation of Lep 1 0.01 0.15 0.19
105 INT327813 Rab8a Regulation of Lep 1 0.01 0.15 0.19
106 INT303964 Lep Positive_regulation of Icam1 1 0.24 0.35 0.19
107 INT333888 Lep Regulation of Localization of GAG 1 0.68 0.38 0.19
108 INT251665 LRP5 Negative_regulation of Ache 1 0.31 0.39 0.19
109 INT214170 Binding of DST and Lep 1 0.02 0.17 0.18
110 INT266046 Cstb Regulation of Gene_expression of Adrm1 1 0.00 0.7 0.18
111 INT303981 Lep Positive_regulation of Localization of CXCL1 1 0.02 0.34 0.18
112 INT175596 Binding of ACAT1 and HGF 1 0.01 1.58 0.18
113 INT226988 Lias Positive_regulation of Localization of Lep 1 0.08 0.3 0.17
114 INT303967 Lep Positive_regulation of Gene_expression of Icam1 1 0.24 0.58 0.16
115 INT303980 Lep Positive_regulation of Transcription of IL2 1 0.10 0.24 0.16
116 INT217667 LEP Negative_regulation of Localization of INS 1 0.15 1.18 0.14
117 INT217664 LEP Negative_regulation of INS 1 0.15 1.18 0.14
118 INT323877 LEP Positive_regulation of SOAT1 1 0.20 1.26 0.14
119 INT139975 Binding of LEP and Prl 1 0.02 0.49 0.13
120 INT328060 LEP Positive_regulation of FAAH 1 0.06 0.7 0.13
121 INT346714 LEP Regulation of GALP 1 0.06 0.08 0.13
122 INT81179 LEP Regulation of Localization of GH1 1 0.11 0.91 0.12
123 INT214141 Binding of Lep and Lepr 1 0.32 0.82 0.12
124 INT150532 LEP Negative_regulation of Adipoq 1 0.00 1.34 0.12
125 INT283719 Id2 Regulation of Regulation of Hes7 1 0.00 0.31 0.12
126 INT150533 Positive_regulation of LEP Negative_regulation of Adipoq 1 0.00 1.34 0.12
127 INT164746 Binding of LEP and Adipoq 1 0.07 0.69 0.12
128 INT323871 LEP Regulation of Gene_expression of IGF1 1 0.14 1.19 0.11
129 INT270746 INS Regulation of LEP 1 0.07 0.72 0.11
130 INT294742 Lep Positive_regulation of Localization of Icam1 1 0.15 0.48 0.11
131 INT163817 Lep Positive_regulation of Phosphorylation of Akt1 1 0.33 0.31 0.11
132 INT222472 Lep Positive_regulation of Localization of Cartpt 1 0.05 0 0.11
133 INT303989 Lep Positive_regulation of IL12A 1 0.05 0.39 0.11
134 INT283710 Binding of Id2 and Hes7 1 0.01 0.13 0.11
135 INT303966 Lep Regulation of Il1 2 0.09 0.41 0.1
136 INT303990 Binding of Lep and Positive_regulation of Gene_expression of LPL 1 0.03 0.35 0.1
137 INT323879 LEP Regulation of SOAT1 1 0.15 1.15 0.1
138 INT204086 TNF Positive_regulation of Gene_expression of LEP 1 0.48 0.74 0.1
139 INT304000 Lep Negative_regulation of Positive_regulation of CASP8 1 0.04 0.25 0.1
140 INT123864 Lep Positive_regulation of Positive_regulation of Cck 1 0.45 0.1 0.09
141 INT242324 Lep Regulation of Gene_expression of Ucp1 1 0.58 1.47 0.09
142 INT142418 Lep Positive_regulation of Gene_expression of Ghrl 1 0.48 1.66 0.09
143 INT306794 Binding of LEP and COPD 1 0.15 3.94 0.09
144 INT213482 Lep Positive_regulation of Mapk1 1 0.06 0.08 0.09
145 INT300486 LEP Positive_regulation of ROS1 1 0.15 0.91 0.09
146 INT323868 LEP Regulation of Transcription of COL1A2 1 0.10 0.98 0.09
147 INT129624 Bmp7 Positive_regulation of Gene_expression of Id2 1 0.26 0.31 0.08
148 INT129625 Id2 Positive_regulation of Gene_expression of Bmp7 1 0.24 0.31 0.08
149 INT222545 Lep Negative_regulation of Nmb 1 0.04 0.52 0.08
150 INT123866 Lep Negative_regulation of Olfr544 1 0.00 0.09 0.08
151 INT306945 NAMPT Positive_regulation of Positive_regulation of MAPK1 1 0.10 0.33 0.08
152 INT303999 Lep Positive_regulation of Gene_expression of ITGA2 1 0.06 0.29 0.08
153 INT332287 LEP Positive_regulation of Phosphorylation of IRS1 1 0.20 1.48 0.08
154 INT323881 BMI1 Regulation of Gene_expression of LEP 1 0.03 1.09 0.08
155 INT323876 LEP Regulation of COL1A2 1 0.10 0.86 0.08
156 INT268325 Lep Positive_regulation of Ptgs2 1 0.09 0.39 0.08
157 INT272774 Binding of Mc4r and Fto 1 0.30 0.66 0.08
158 INT283721 Binding of Lpin1 and Id2 1 0.38 0.18 0.08
159 INT303970 Lep Positive_regulation of Gene_expression of Itga2 1 0.09 0.29 0.08
160 INT294743 Lep Positive_regulation of Transcription of Il6 1 0.18 0.42 0.07
161 INT129627 Bmp7 Positive_regulation of Id2 1 0.24 0.25 0.07
162 INT294740 Lep Positive_regulation of Transcription of Ccl2 1 0.08 0.42 0.07
163 INT147675 Positive_regulation of Atf2 Positive_regulation of GRP 1 0.04 0 0.07
164 INT323872 LEP Positive_regulation of Gene_expression of IGF1 1 0.35 0.77 0.07
165 INT303997 IL1RL1 Positive_regulation of Lep 1 0.01 0.2 0.07
166 INT286563 Binding of Id2 and P1Ehs1 1 0.00 0.17 0.06
167 INT286591 Binding of PKD1 and Id2 1 0.07 0.17 0.06
168 INT214153 Lep Regulation of Transcription of Nucb2 1 0.35 0.15 0.06
169 INT253377 Lep Negative_regulation of Phosphorylation of Prkaa2 1 0.24 1.24 0.06
170 INT323878 Binding of LEP and MMP13 1 0.17 0.77 0.05
171 INT267152 Binding of LEP and DDX12P 1 0.00 0.69 0.05
172 INT267157 LEP Positive_regulation of ADIPOQ 1 0.10 0.51 0.05
173 INT345965 Binding of Lep and al44 1 0.01 1.43 0.05
174 INT314135 Negative_regulation of Nos2 Positive_regulation of Lep 1 0.52 0.44 0.05
175 INT327821 GPRC6A Regulation of Gene_expression of Lep 1 0.00 0.5 0.05
176 INT327822 INCENP Regulation of Gene_expression of Lep 1 0.00 0.5 0.05
177 INT267153 Binding of LEP and SUGT1 1 0.02 0.69 0.05
178 INT292816 Binding of KCNJ11 and FTO 1 0.46 0.49 0.05
179 INT292815 Binding of CDC123 and FTO 1 0.50 0.48 0.05
180 INT253376 Lep Regulation of Mtor 1 0.17 0.08 0.04
181 INT320440 Binding of Adrm1 and Psmb10 1 0.00 0 0.04
182 INT303986 Lep Positive_regulation of Gene_expression of TNF 1 0.49 0.29 0.04
183 INT332684 Binding of Edn1 and Lep 1 0.09 1.11 0.04
184 INT170328 Gene_expression of Ido1 Positive_regulation of Hmga2 1 0.01 0.13 0.04
185 INT253363 Lep Regulation of Prkaa2 1 0.15 0.08 0.04
186 INT222534 Gnrh1 Positive_regulation of Localization of Lep 1 0.07 0 0.04
187 INT303996 Lep Positive_regulation of Gene_expression of IL12A 1 0.08 0.29 0.04
188 INT303965 Lep Positive_regulation of Gene_expression of Il6 1 0.07 0.29 0.04
189 INT254433 Binding of Lrp5 and Sost 2 0.39 1.51 0.03
190 INT249046 Binding of LEP and ARID1B 1 0.01 1.3 0.03
191 INT231438 LEP Positive_regulation of Negative_regulation of NOS3 1 0.09 0.32 0.03
192 INT253374 Lep Positive_regulation of Phosphorylation of Eif4ebp1 1 0.04 0.16 0.03
193 INT253375 Lep Positive_regulation of Phosphorylation of Rps6kb1 1 0.41 0.16 0.03
194 INT283720 Id2 Negative_regulation of Transcription of Cdkn2b 1 0.18 0.11 0.03
195 INT283722 Id2 Negative_regulation of Transcription of CDKN1A 1 0.45 0.11 0.03
196 INT253414 Lep Negative_regulation of BCL2A1 1 0.16 0 0.03
197 INT283712 Id2 Regulation of Gene_expression of Fos 1 0.43 0 0.03
198 INT231439 LEP Positive_regulation of Negative_regulation of AKT1 1 0.06 0.32 0.03
199 INT167565 Binding of ERG and LRP5 1 0.02 0.94 0.03
200 INT333885 Lep Positive_regulation of Il1 1 0.17 0.05 0.03

Single Events

The table below shows the top 100 pain related interactions that have been reported for adipose tissue development. They are ordered first by their pain relevance and then by number of times they were reported in adipose tissue development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT17881 Gene_expression of LEP 278 0.78 221.61 48.31
2 INT101483 Gene_expression of Lep 159 0.78 104.77 25.12
3 INT76123 Gene_expression of Lep 193 0.78 94.17 22.76
4 INT82434 Positive_regulation of LEP 117 0.70 95.45 20.22
5 INT62681 Negative_regulation of LEP 93 0.59 66.97 15.77
6 INT75908 Regulation of LEP 77 0.60 60.16 15.19
7 INT73641 Regulation of Lep 45 0.62 26.2 12.59
8 INT126743 Positive_regulation of Gene_expression of LEP 61 0.66 50.02 11.17
9 INT82079 Positive_regulation of Lep 79 0.70 40 11.07
10 INT101481 Positive_regulation of Lep 81 0.69 62.59 9.95
11 INT82078 Negative_regulation of Lep 54 0.59 20.47 9.38
12 INT82082 Localization of Lep 63 0.81 26.41 8.56
13 INT75907 Binding of LEP 53 0.46 46.65 8.44
14 INT61114 Gene_expression of Ppard 23 0.75 14.98 6.62
15 INT146594 Negative_regulation of Gene_expression of LEP 25 0.42 18.88 5.71
16 INT88286 Phosphorylation of Atf2 11 0.66 1.93 5.69
17 INT101482 Negative_regulation of Lep 53 0.54 33.59 5.65
18 INT65356 Localization of LEP 46 0.79 41.17 5.43
19 INT91338 Binding of Lep 31 0.48 26.86 5.39
20 INT102935 Regulation of Lep 31 0.60 18.47 5.24
21 INT88282 Positive_regulation of Phosphorylation of Atf2 8 0.44 1.77 4.85
22 INT97391 Binding of Lep 18 0.48 8.97 4.47
23 INT163581 Localization of Lep 27 0.79 18.99 4.08
24 INT119606 Regulation of Gene_expression of LEP 17 0.45 17.96 3.75
25 INT174054 Positive_regulation of Gene_expression of Lep 25 0.69 21.3 3.72
26 INT84891 Gene_expression of PPARD 10 0.78 6.8 3.64
27 INT77251 Positive_regulation of Atf2 8 0.70 2.45 3.62
28 INT212563 Gene_expression of Adrm1 26 0.13 11.46 3.58
29 INT40368 Positive_regulation of LRP5 5 0.49 3.19 3.51
30 INT82077 Positive_regulation of Gene_expression of Lep 32 0.70 17.9 3.5
31 INT102034 Positive_regulation of Ppard 10 0.69 3.97 3.17
32 INT84890 Negative_regulation of PPARD 7 0.59 3.27 3.1
33 INT34977 Gene_expression of Hmga2 11 0.76 12.39 3.07
34 INT112758 Binding of Ppard 7 0.37 3.6 2.87
35 INT306949 Gene_expression of NAMPT 27 0.67 24.47 2.86
36 INT97443 Positive_regulation of Positive_regulation of LEP 13 0.50 11.91 2.65
37 INT88285 Transcription of Atf2 4 0.36 1.56 2.62
38 INT52326 Negative_regulation of Atf2 7 0.45 0.94 2.5
39 INT102033 Negative_regulation of Ppard 5 0.37 4.14 2.48
40 INT221762 Regulation of Gene_expression of Adrm1 4 0.07 4.45 2.42
41 INT103487 Positive_regulation of Positive_regulation of Lep 9 0.67 4.08 2.38
42 INT101516 Positive_regulation of PPARD 8 0.49 4.75 2.19
43 INT82081 Regulation of Gene_expression of Lep 11 0.53 7.78 2.12
44 INT83392 Transcription of Lep 6 0.54 5.07 2.04
45 INT82083 Negative_regulation of Gene_expression of Lep 12 0.56 8.07 1.75
46 INT183276 Negative_regulation of Adrm1 10 0.04 7.25 1.74
47 INT129610 Gene_expression of Id2 7 0.74 17.07 1.69
48 INT95056 Positive_regulation of Gene_expression of Ppard 5 0.52 3.84 1.6
49 INT53343 Positive_regulation of NAMPT 13 0.60 10.94 1.58
50 INT84889 Positive_regulation of Gene_expression of PPARD 4 0.70 2.94 1.49
51 INT110444 Positive_regulation of Atf2 7 0.50 2 1.48
52 INT84888 Binding of PPARD 5 0.48 2.82 1.45
53 INT214115 Regulation of Gene_expression of Lep 9 0.61 7.37 1.44
54 INT132495 Negative_regulation of Gene_expression of Ppard 4 0.44 2.64 1.28
55 INT130207 Phosphorylation of ATF2 5 0.60 1.34 1.25
56 INT167270 Negative_regulation of Gene_expression of Lep 13 0.55 5.48 1.19
57 INT213465 Transcription of Lep 4 0.68 2.11 1.15
58 INT253813 Regulation of Negative_regulation of Lep 2 0.45 1.01 1.12
59 INT82084 Positive_regulation of Localization of Lep 11 0.70 4.65 1.11
60 INT69421 Positive_regulation of ACAT1 5 0.23 1.56 1.08
61 INT107653 Gene_expression of ACAT1 9 0.60 4.74 1.03
62 INT130209 Positive_regulation of Phosphorylation of ATF2 3 0.36 1.15 1.03
63 INT112759 Negative_regulation of Binding of Ppard 2 0.39 2.08 0.99
64 INT83983 Phosphorylation of Atf2 6 0.63 2 0.95
65 INT34978 Negative_regulation of Gene_expression of Hmga2 2 0.42 1.53 0.95
66 INT83984 Positive_regulation of Positive_regulation of Atf2 1 0.44 0.48 0.89
67 INT117308 Negative_regulation of Localization of Lep 3 0.59 2.16 0.86
68 INT69913 Binding of ATF2 6 0.13 0.83 0.84
69 INT333883 Positive_regulation of Positive_regulation of Lep 2 0.46 1.06 0.83
70 INT84892 Negative_regulation of Gene_expression of PPARD 2 0.43 1.85 0.83
71 INT72334 Negative_regulation of LRP5 7 0.35 1.71 0.81
72 INT82080 Regulation of Localization of Lep 2 0.45 1.36 0.76
73 INT156533 Transcription of LEP 9 0.69 4.35 0.74
74 INT40369 Gene_expression of LRP5 8 0.55 5.63 0.74
75 INT306954 Binding of NAMPT 8 0.36 7.98 0.74
76 INT213471 Positive_regulation of Localization of Lep 4 0.48 2.65 0.74
77 INT69922 Positive_regulation of ATF2 3 0.05 1.28 0.74
78 INT306951 Positive_regulation of Gene_expression of NAMPT 1 0.60 6.08 0.72
79 INT231558 Regulation of LRP5 2 0.24 1.02 0.68
80 INT78183 Negative_regulation of Adrm1 8 0.09 3.4 0.65
81 INT212562 Positive_regulation of Adrm1 16 0.10 5.08 0.62
82 INT101484 Regulation of Positive_regulation of Lep 3 0.45 1.68 0.61
83 INT345957 Positive_regulation of Binding of Lep 2 0.38 2.03 0.6
84 INT83391 Negative_regulation of Transcription of Lep 1 0.43 0.34 0.6
85 INT103888 Gene_expression of Atf2 7 0.58 1.69 0.59
86 INT306798 Protein_catabolism of LEP 1 0.65 2.45 0.58
87 INT129615 Positive_regulation of Id2 2 0.66 2.22 0.57
88 INT40367 Positive_regulation of Gene_expression of LRP5 1 0.09 0 0.57
89 INT88290 Positive_regulation of Transcription of Atf2 1 0.31 0.09 0.56
90 INT88291 Regulation of Transcription of Atf2 1 0.18 0.1 0.55
91 INT272772 Gene_expression of Fto 2 0.76 3.76 0.52
92 INT306959 Transcription of NAMPT 2 0.62 1.19 0.52
93 INT105210 Positive_regulation of Adrm1 7 0.06 4.09 0.5
94 INT343800 Negative_regulation of Transcription of NAMPT 1 0.37 0.37 0.5
95 INT142972 Gene_expression of ID2 6 0.54 5.92 0.49
96 INT101515 Negative_regulation of Positive_regulation of PPARD 2 0.35 0.68 0.47
97 INT82819 Negative_regulation of Negative_regulation of LEP 3 0.56 2.22 0.46
98 INT84893 Negative_regulation of Binding of PPARD 1 0.43 0.5 0.46
99 INT69420 Positive_regulation of Positive_regulation of ACAT1 1 0.23 0.17 0.45
100 INT93214 Positive_regulation of Phosphorylation of Atf2 2 0.38 0.99 0.44
101 INT250468 Positive_regulation of Gene_expression of Adrm1 2 0.04 2.26 0.44
102 INT132946 Negative_regulation of Positive_regulation of Ppard 1 0.42 0.09 0.44
103 INT147482 Regulation of Phosphorylation of Atf2 1 0.22 0.56 0.43
104 INT102934 Positive_regulation of Regulation of Lep 2 0.50 0.55 0.42
105 INT69915 Regulation of ATF2 2 0.34 0.81 0.42
106 INT83985 Negative_regulation of Positive_regulation of Atf2 1 0.43 0.26 0.42
107 INT323765 Negative_regulation of Binding of Lep 1 0.37 0.91 0.42
108 INT187726 Positive_regulation of Localization of LEP 5 0.50 5.31 0.41
109 INT246514 Negative_regulation of NAMPT 4 0.51 2.98 0.37
110 INT212565 Regulation of Adrm1 3 0.04 2.41 0.36
111 INT283683 Binding of Id2 5 0.35 0.8 0.35
112 INT306957 Localization of NAMPT 1 0.70 8.78 0.35
113 INT212564 Negative_regulation of Gene_expression of Adrm1 3 0.05 1.7 0.34
114 INT306952 Regulation of NAMPT 4 0.53 8.52 0.33
115 INT255920 Gene_expression of ATF2 3 0.75 1.52 0.33
116 INT303962 Phosphorylation of Lep 2 0.80 5.2 0.31
117 INT213467 Negative_regulation of Localization of Lep 2 0.40 1.11 0.31
118 INT156534 Positive_regulation of Transcription of LEP 1 0.14 0.34 0.3
119 INT144419 Regulation of Ppard 1 0.24 0.91 0.3
120 INT141781 Positive_regulation of Negative_regulation of LEP 1 0.46 0.37 0.29
121 INT196937 Positive_regulation of Hmga2 3 0.68 2.47 0.28
122 INT61115 Localization of Ppard 2 0.66 1.99 0.28
123 INT83986 Localization of Atf2 1 0.81 0.27 0.28
124 INT159198 Positive_regulation of Binding of Ppard 1 0.34 0.68 0.28
125 INT297804 Regulation of Lrp5 6 0.60 2.31 0.27
126 INT254427 Binding of Lrp5 10 0.48 5.43 0.26
127 INT93217 Negative_regulation of Phosphorylation of Atf2 1 0.12 0.08 0.26
128 INT334543 Negative_regulation of Positive_regulation of LRP5 1 0.23 1.81 0.25
129 INT150977 Regulation of Regulation of LEP 3 0.37 2.07 0.23
130 INT173655 Binding of LRP5 10 0.39 3.06 0.22
131 INT129612 Positive_regulation of Gene_expression of Id2 4 0.67 3.61 0.22
132 INT142417 Positive_regulation of Transcription of Lep 2 0.52 2.63 0.22
133 INT255901 Transcription of ATF2 1 0.25 0.12 0.22
134 INT250467 Localization of Adrm1 2 0.06 0.97 0.19
135 INT250469 Positive_regulation of Localization of Adrm1 2 0.04 0.97 0.19
136 INT169047 Positive_regulation of Gene_expression of Atf2 1 0.36 0.31 0.19
137 INT254429 Negative_regulation of Lrp5 4 0.57 1.95 0.18
138 INT186140 Gene_expression of Adrm1 2 0.06 1.01 0.18
139 INT163816 Phosphorylation of Lep 2 0.63 2.2 0.17
140 INT333880 Protein_catabolism of Lep 1 0.65 0.34 0.17
141 INT157134 Regulation of Localization of LEP 1 0.09 0.5 0.16
142 INT333882 Regulation of Binding of Lep 1 0.45 0.07 0.16
143 INT204088 Regulation of Negative_regulation of LEP 1 0.59 1.16 0.16
144 INT300489 Negative_regulation of Binding of LEP 1 0.41 1.12 0.15
145 INT278979 Negative_regulation of Positive_regulation of LEP 2 0.40 0.81 0.14
146 INT187723 Regulation of Positive_regulation of LEP 3 0.42 2.29 0.13
147 INT323898 Regulation of Phosphorylation of LEP 1 0.42 1.25 0.13
148 INT323895 Phosphorylation of LEP 1 0.76 1.23 0.13
149 INT283702 Transcription of Id2 1 0.66 0.64 0.13
150 INT157241 Negative_regulation of Localization of LEP 5 0.56 2.1 0.12
151 INT163815 Negative_regulation of Negative_regulation of Lep 1 0.43 0.32 0.12
152 INT283708 Localization of Id2 2 0.71 0.72 0.11
153 INT142970 Positive_regulation of Gene_expression of ID2 2 0.40 2.39 0.11
154 INT186516 Regulation of PPARD 1 0.15 1.12 0.11
155 INT142968 Negative_regulation of Gene_expression of ID2 1 0.19 0.98 0.11
156 INT226984 Regulation of Transcription of Lep 1 0.27 0.3 0.11
157 INT236140 Negative_regulation of Fto 1 0.03 2.42 0.11
158 INT242263 Regulation of ACAT1 4 0.09 0.66 0.1
159 INT69920 Negative_regulation of Binding of ATF2 1 0.06 0 0.1
160 INT69918 Negative_regulation of ATF2 1 0.06 0 0.1
161 INT212172 Binding of Adrm1 7 0.36 1.38 0.09
162 INT142971 Negative_regulation of Positive_regulation of ID2 1 0.20 0.69 0.09
163 INT306948 Positive_regulation of Localization of NAMPT 1 0.40 0.8 0.09
164 INT142969 Positive_regulation of ID2 1 0.21 0.68 0.09
165 INT170298 Regulation of Gene_expression of Hmga2 1 0.01 0.48 0.08
166 INT129614 Positive_regulation of Positive_regulation of Id2 1 0.48 0.31 0.08
167 INT187729 Positive_regulation of Binding of LEP 1 0.18 0.3 0.08
168 INT272773 Binding of Fto 1 0.41 0.66 0.08
169 INT300138 Positive_regulation of FTO 2 0.36 2.64 0.07
170 INT213475 Negative_regulation of Positive_regulation of Lep 2 0.40 1.79 0.07
171 INT147663 Positive_regulation of Positive_regulation of Atf2 1 0.33 0.99 0.07
172 INT254426 Gene_expression of Lrp5 5 0.67 3.28 0.06
173 INT242264 Binding of ACAT1 3 0.12 1.05 0.06
174 INT170300 Positive_regulation of Gene_expression of Hmga2 2 0.68 4.51 0.06
175 INT170302 Regulation of Hmga2 2 0.44 0.94 0.06
176 INT213466 Negative_regulation of Regulation of Lep 1 0.41 0 0.06
177 INT129613 Regulation of Gene_expression of Id2 1 0.43 0.24 0.06
178 INT306955 Negative_regulation of Gene_expression of NAMPT 1 0.51 0.33 0.06
179 INT223571 Localization of PPARD 1 0.73 0.39 0.06
180 INT215445 Transcription of Adrm1 2 0.08 0.08 0.05
181 INT292953 Gene_expression of Fto 1 0.78 30.08 0.05
182 INT242265 Negative_regulation of Gene_expression of ACAT1 3 0.14 0 0.04
183 INT242172 Protein_catabolism of LRP5 1 0.64 0.06 0.04
184 INT225443 Binding of Atf2 1 0.07 0.27 0.03
185 INT319131 Positive_regulation of Lrp5 1 0.43 0.36 0.03
186 INT76371 Protein_catabolism of Hmga2 1 0.02 0.06 0.03
187 INT313942 Gene_expression of FTO 3 0.62 4.73 0
188 INT277114 Binding of FTO 3 0.34 3.93 0
189 INT297757 Transcription of Lrp5 2 0.68 0.82 0
190 INT39570 Localization of ACAT1 2 0.75 0.44 0
191 INT253406 Negative_regulation of Positive_regulation of Lep 2 0.41 0.74 0
192 INT297820 Regulation of Transcription of Lrp5 2 0.44 0.83 0
193 INT307613 Phosphorylation of LRP5 1 0.08 0.1 0
194 INT208931 Localization of Atf2 1 0.01 0 0
195 INT196931 Phosphorylation of Hmga2 1 0.80 0.4 0
196 INT150408 Regulation of Regulation of Lep 1 0.27 0 0
197 INT305226 Negative_regulation of Phosphorylation of Lep 1 0.42 1.89 0
198 INT173644 Negative_regulation of Gene_expression of LRP5 1 0.15 0.59 0
199 INT305239 Positive_regulation of Phosphorylation of Lep 1 0.43 1.09 0
200 INT292960 Positive_regulation of Transcription of Fto 1 0.50 0.91 0
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